Ryan A. Langlois, Ph.D. - Publications

Affiliations: 
2010 Immunology University of Iowa, Iowa City, IA 
Area:
Cell Biology, Microbiology Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Phan T, Ye Q, Stach C, Lin YC, Cao H, Bowen A, Langlois RA, Hu WS. Synthetic Cell Lines for Inducible Packaging of Influenza A Virus. Acs Synthetic Biology. PMID 38259154 DOI: 10.1021/acssynbio.3c00526  0.391
2023 King CR, Liu Y, Amato KA, Schaack GA, Mickelson C, Sanders AE, Hu T, Gupta S, Langlois RA, Smith JA, Mehle A. Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection. Cell Host & Microbe. PMID 37652009 DOI: 10.1016/j.chom.2023.08.001  0.305
2023 Jaeger AS, Crooks CM, Weiler AM, Bliss MI, Rybarczyk S, Richardson A, Einwalter M, Peterson E, Capuano S, Barkhymer A, Becker JT, Greene JT, Freedman TS, Langlois RA, Friedrich TC, et al. Primary infection with Zika virus provides one-way heterologous protection against Spondweni virus infection in rhesus macaques. Science Advances. 9: eadg3444. PMID 37390207 DOI: 10.1126/sciadv.adg3444  0.719
2023 Cable J, Sun J, Cheon IS, Vaughan AE, Castro IA, Stein SR, López CB, Gostic KM, Openshaw PJM, Ellebedy AH, Wack A, Hutchinson E, Thomas MM, Langlois RA, Lingwood D, et al. Respiratory viruses: New frontiers-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 36722473 DOI: 10.1111/nyas.14958  0.311
2022 Kenney AD, Aron SL, Gilbert C, Kumar N, Chen P, Eddy A, Zhang L, Zani A, Vargas-Maldonado N, Speaks S, Kawahara J, Denz PJ, Dorn L, Accornero F, Ma J, ... ... Langlois RA, et al. Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis. Science Advances. 8: eabm5371. PMID 35544568 DOI: 10.1126/sciadv.abm5371  0.352
2022 Roach SN, Fiege JK, Shepherd FK, Wiggen TD, Hunter RC, Langlois RA. Respiratory Influenza Virus Infection Causes Dynamic Tuft Cell and Innate Lymphoid Cell Changes in the Small Intestine. Journal of Virology. 96: e0035222. PMID 35446142 DOI: 10.1128/jvi.00352-22  0.427
2022 Shen SS, Nanda H, Aliferis C, Langlois RA. Characterization of influenza A virus induced transposons reveals a subgroup of transposons likely possessing the regulatory role as eRNAs. Scientific Reports. 12: 2188. PMID 35140280 DOI: 10.1038/s41598-022-06196-6  0.34
2021 Randolph HE, Fiege JK, Thielen BK, Mickelson CK, Shiratori M, Barroso-Batista J, Langlois RA, Barreiro LB. Genetic ancestry effects on the response to viral infection are pervasive but cell type specific. Science (New York, N.Y.). 374: 1127-1133. PMID 34822289 DOI: 10.1126/science.abg0928  0.376
2021 Matchett WE, Joag V, Stolley JM, Shepherd FK, Quarnstrom CF, Mickelson CK, Wijeyesinghe S, Soerens AG, Becker S, Thiede JM, Weyu E, O'Flanagan S, Walter JA, Vu MN, Menachery VD, ... ... Langlois RA, et al. Nucleocapsid vaccine elicits spike-independent SARS-CoV-2 protective immunity. Biorxiv : the Preprint Server For Biology. PMID 33948591 DOI: 10.1101/2021.04.26.441518  0.309
2021 Krueger PD, Goldberg MF, Hong SW, Osum KC, Langlois RA, Kotov DI, Dileepan T, Jenkins MK. Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells. Immunity. PMID 33773107 DOI: 10.1016/j.immuni.2021.03.006  0.499
2021 Fiege JK, Thiede JM, Nanda HA, Matchett WE, Moore PJ, Montanari NR, Thielen BK, Daniel J, Stanley E, Hunter RC, Menachery VD, Shen SS, Bold TD, Langlois RA. Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium. Plos Pathogens. 17: e1009292. PMID 33507952 DOI: 10.1371/journal.ppat.1009292  0.457
2021 Joag V, Wijeyesinghe S, Stolley JM, Quarnstrom CF, Dileepan T, Soerens AG, Sangala JA, O'Flanagan SD, Gavil NV, Hong SW, Bhela S, Gangadhara S, Weyu E, Matchett WE, Thiede J, ... ... Langlois RA, et al. Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 33441437 DOI: 10.4049/jimmunol.2001400  0.533
2020 Fiege JK, Thiede JM, Nanda H, Matchett WE, Moore PJ, Montanari NR, Thielen BK, Daniel J, Stanley E, Hunter RC, Menachery VD, Shen SS, Bold TD, Langlois RA. Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium. Biorxiv : the Preprint Server For Biology. PMID 33106802 DOI: 10.1101/2020.10.19.343954  0.457
2020 Fay EJ, Aron SL, Macchietto MG, Markman MW, Esser-Nobis K, Gale M, Shen S, Langlois RA. Cell type- and replication stage-specific influenza virus responses in vivo. Plos Pathogens. 16: e1008760. PMID 32790753 DOI: 10.1371/Journal.Ppat.1008760  0.55
2020 Cosma GL, Lobby JL, Fay EJ, Siciliano NA, Langlois RA, Eisenlohr LC. Kinetically distinct processing pathways diversify the CD8 T cell response to a single viral epitope. Proceedings of the National Academy of Sciences of the United States of America. PMID 32719124 DOI: 10.1073/Pnas.2004372117  0.489
2020 Stolley JM, Johnston TS, Soerens AG, Beura LK, Rosato PC, Joag V, Wijeyesinghe SP, Langlois RA, Osum KC, Mitchell JS, Masopust D. Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection. The Journal of Experimental Medicine. 217. PMID 32568362 DOI: 10.1084/Jem.20192197  0.596
2020 Macchietto MG, Langlois RA, Shen SS. Virus-induced transposable element expression up-regulation in human and mouse host cells. Life Science Alliance. 3. PMID 31964680 DOI: 10.26508/lsa.201900536  0.435
2020 Meyerholz DK, Fiege JE, Block KE, Pierson M, Pape KA, Jenkins MK, Hamilton SE, Masopust D, Langlois RA. Dirty Mice Have Altered Influenza A Virus Clearance And Lesions Compared To SPF Mice: A Proposed Model For Study Of Vaccine Response In Humans The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04770  0.397
2019 Fiege JK, Stone IA, Dumm RE, Waring BM, Fife BT, Agudo J, Brown BD, Heaton NS, Langlois RA. Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance. Plos Pathogens. 15: e1008077. PMID 31557273 DOI: 10.1371/Journal.Ppat.1008077  0.633
2019 Hemann EA, Green R, Turnbull JB, Langlois RA, Savan R, Gale M. Interferon-λ modulates dendritic cells to facilitate T cell immunity during infection with influenza A virus. Nature Immunology. PMID 31235953 DOI: 10.1038/S41590-019-0408-Z  0.769
2019 Fiege JK, Stone IA, Fay EJ, Markman MW, Wijeyesinghe S, Macchietto MG, Shen S, Masopust D, Langlois RA. The Impact of TCR Signal Strength on Resident Memory T Cell Formation during Influenza Virus Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 31235552 DOI: 10.4049/Jimmunol.1900093  0.543
2019 Hornick EE, Dagvadorj J, Zacharias ZR, Miller AM, Langlois RA, Chen P, Legge KL, Bishop GA, Sutterwala FS, Cassel SL. Dendritic cell NLRC4 regulates influenza A virus-specific CD4 T cell responses through FasL expression. The Journal of Clinical Investigation. 130. PMID 31038471 DOI: 10.1172/Jci124937  0.787
2019 Kotov DI, Mitchell JS, Pengo T, Ruedl C, Way SS, Langlois RA, Fife BT, Jenkins MK. TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2. Journal of Immunology (Baltimore, Md. : 1950). PMID 30858199 DOI: 10.4049/Jimmunol.1801609  0.454
2019 Dumm RE, Fiege JK, Waring BM, Kuo CT, Langlois RA, Heaton NS. Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function. Nature Communications. 10: 779. PMID 30770807 DOI: 10.1038/S41467-019-08617-Z  0.563
2019 Thielen BK, Christensen J, K. Strain A, Shen S, Langlois R. 408. Single-cell Sequencing Identifies Variability in Host Response Among Different Genera of Influenza Viruses Open Forum Infectious Diseases. 6: S207-S207. DOI: 10.1093/Ofid/Ofz360.481  0.566
2018 Fay EJ, Aron SL, Stone IA, Waring BM, Plemper RK, Langlois RA. Engineered small molecule control of influenza A virus replication. Journal of Virology. PMID 30282710 DOI: 10.1128/Jvi.01677-18  0.373
2018 Fay EJ, Langlois RA. MicroRNA-Attenuated Virus Vaccines. Non-Coding Rna. 4. PMID 30279330 DOI: 10.3390/Ncrna4040025  0.33
2018 Sjaastad LE, Fay EJ, Fiege JK, Macchietto MG, Stone IA, Markman MW, Shen S, Langlois RA. Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 30181264 DOI: 10.1073/Pnas.1807516115  0.553
2018 Schmidt ME, Knudson CJ, Hartwig SM, Pewe LL, Meyerholz DK, Langlois RA, Harty JT, Varga SM. Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection. Plos Pathogens. 14: e1006810. PMID 29293660 DOI: 10.1371/Journal.Ppat.1006810  0.654
2017 Waring BM, Sjaastad LE, Fiege JK, Fay EJ, Reyes I, Moriarity B, Langlois RA. microRNA-based attenuation of influenza virus across susceptible hosts. Journal of Virology. PMID 29093096 DOI: 10.1128/Jvi.01741-17  0.418
2016 Hamilton JR, Sachs D, Lim JK, Langlois RA, Palese P, Heaton NS. Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27001854 DOI: 10.1073/Pnas.1522376113  0.582
2015 Hemann EA, Sjaastad LE, Langlois RA, Legge KL. Plasmacytoid Dendritic Cells Require Direct Infection To Sustain the Pulmonary Influenza A Virus-Specific CD8 T Cell Response. Journal of Virology. 90: 2830-7. PMID 26719269 DOI: 10.1128/Jvi.02546-15  0.772
2015 Fiege JK, Langlois RA. Investigating influenza A virus infection: tools to track infection and limit tropism. Journal of Virology. 89: 6167-70. PMID 25855737 DOI: 10.1128/Jvi.00462-15  0.474
2014 Heaton NS, Langlois RA, Sachs D, Lim JK, Palese P, tenOever BR. Long-term survival of influenza virus infected club cells drives immunopathology. The Journal of Experimental Medicine. 211: 1707-14. PMID 25135297 DOI: 10.1084/Jem.20140488  0.563
2014 Backes S, Langlois RA, Schmid S, Varble A, Shim JV, Sachs D, tenOever BR. The Mammalian response to virus infection is independent of small RNA silencing. Cell Reports. 8: 114-25. PMID 24953656 DOI: 10.1016/J.Celrep.2014.05.038  0.476
2013 Langlois RA, Albrecht RA, Kimble B, Sutton T, Shapiro JS, Finch C, Angel M, Chua MA, Gonzalez-Reiche AS, Xu K, Perez D, García-Sastre A, tenOever BR. MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies. Nature Biotechnology. 31: 844-7. PMID 23934176 DOI: 10.1038/Nbt.2666  0.42
2013 Chua MA, Schmid S, Perez JT, Langlois RA, Tenoever BR. Influenza A virus utilizes suboptimal splicing to coordinate the timing of infection. Cell Reports. 3: 23-9. PMID 23333274 DOI: 10.1016/J.Celrep.2012.12.010  0.449
2012 Pica N, Langlois RA, Krammer F, Margine I, Palese P. NS1-truncated live attenuated virus vaccine provides robust protection to aged mice from viral challenge. Journal of Virology. 86: 10293-301. PMID 22787224 DOI: 10.1128/Jvi.01131-12  0.4
2012 Langlois RA, Varble A, Chua MA, García-Sastre A, tenOever BR. Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses. Proceedings of the National Academy of Sciences of the United States of America. 109: 12117-22. PMID 22778433 DOI: 10.1073/Pnas.1206039109  0.625
2012 Pham AM, Langlois RA, TenOever BR. Replication in cells of hematopoietic origin is necessary for Dengue virus dissemination. Plos Pathogens. 8: e1002465. PMID 22241991 DOI: 10.1371/Journal.Ppat.1002465  0.503
2011 Brincks EL, Gurung P, Langlois RA, Hemann EA, Legge KL, Griffith TS. The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL. Journal of Immunology (Baltimore, Md. : 1950). 187: 4581-8. PMID 21940678 DOI: 10.4049/Jimmunol.1002241  0.772
2010 Pham NL, Pewe LL, Fleenor CJ, Langlois RA, Legge KL, Badovinac VP, Harty JT. Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly. Proceedings of the National Academy of Sciences of the United States of America. 107: 12198-203. PMID 20616089 DOI: 10.1073/Pnas.1004661107  0.744
2010 Langlois RA, Meyerholz DK, Coleman RA, Cook RT, Waldschmidt TJ, Legge KL. Oseltamivir treatment prevents the increased influenza virus disease severity and lethality occurring in chronic ethanol consuming mice. Alcoholism, Clinical and Experimental Research. 34: 1425-31. PMID 20497135 DOI: 10.1111/J.1530-0277.2010.01226.X  0.701
2010 Langlois RA, Legge KL. Plasmacytoid dendritic cells enhance mortality during lethal influenza infections by eliminating virus-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 4440-6. PMID 20220091 DOI: 10.4049/Jimmunol.0902984  0.774
2007 Langlois RA, Legge KL. Respiratory dendritic cells: mediators of tolerance and immunity. Immunologic Research. 39: 128-45. PMID 17917061 DOI: 10.1007/S12026-007-0077-0  0.668
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