Year |
Citation |
Score |
2015 |
McIntyre NR, Lowe EW, Battistini MR, Leahy JW, Merkler DJ. Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-12. PMID 26024288 DOI: 10.3109/14756366.2015.1046064 |
0.609 |
|
2011 |
McIntyre NR, Franco R, Shelnutt JA, Ferreira GC. Nickel(II) chelatase variants directly evolved from murine ferrochelatase: porphyrin distortion and kinetic mechanism. Biochemistry. 50: 1535-44. PMID 21222436 DOI: 10.1021/Bi101170P |
0.319 |
|
2010 |
McIntyre NR, Lowe EW, Belof JL, Ivkovic M, Shafer J, Space B, Merkler DJ. Evidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunneling. Journal of the American Chemical Society. 132: 16393-402. PMID 21043511 DOI: 10.1021/Ja1019194 |
0.612 |
|
2009 |
McIntyre NR, Lowe EW, Merkler DJ. Imino-oxy acetic acid dealkylation as evidence for an inner-sphere alcohol intermediate in the reaction catalyzed by peptidylglycine alpha-hydroxylating monooxygenase. Journal of the American Chemical Society. 131: 10308-19. PMID 19569683 DOI: 10.1021/Ja902716D |
0.587 |
|
2008 |
Merkler DJ, Asser AS, Baumgart LE, Carballo N, Carpenter SE, Chew GH, Cosner CC, Dusi J, Galloway LC, Lowe AB, Lowe EW, King L, Kendig RD, Kline PC, Malka R, ... ... McIntyre NR, et al. Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM). Bioorganic & Medicinal Chemistry. 16: 10061-74. PMID 18952446 DOI: 10.1016/J.Bmc.2008.10.013 |
0.599 |
|
2006 |
Weiss ST, McIntyre NR, McLaughlin ML, Merkler DJ. The development of molecular clamps as drugs. Drug Discovery Today. 11: 819-24. PMID 16935750 DOI: 10.1016/J.Drudis.2006.07.011 |
0.565 |
|
2006 |
McIntyre NR, Lowe EW, Chew GH, Owen TC, Merkler DJ. Thiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase (PAM). Febs Letters. 580: 521-32. PMID 16405966 DOI: 10.1016/J.Febslet.2005.12.058 |
0.645 |
|
2005 |
Chew GH, Galloway LC, McIntyre NR, Schroder LA, Richards KM, Miller SA, Wright DW, Merkler DJ. Ubiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenase. Febs Letters. 579: 4678-84. PMID 16098968 DOI: 10.1016/J.Febslet.2005.06.089 |
0.623 |
|
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