Jason X. Yuan - Publications

Affiliations: 
Biomedical Sciences University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Medicine and Surgery

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Tang H, Gupta A, Morrisroe SA, Bao C, Schwantes-An TH, Gupta G, Liang S, Sun Y, Chu A, Luo A, Ramamoorthi Elangovan V, Sangam S, Shi Y, Naidu SR, Jheng JR, ... ... Yuan JX, et al. Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension. Circulation. PMID 38695173 DOI: 10.1161/CIRCULATIONAHA.123.065304  0.338
2024 Alotaibi M, Harvey LD, Nichols WC, Pauciulo MW, Hemnes A, Long T, Watrous JD, Begzati A, Tuomilehto J, Havulinna AS, Niiranen TJ, Jousilahti P, Salomaa V, Bertero T, Kim NH, ... ... Yuan JX, et al. Pulmonary primary oxysterol and bile acid synthesis as a predictor of outcomes in pulmonary arterial hypertension. Biorxiv : the Preprint Server For Biology. PMID 38328113 DOI: 10.1101/2024.01.20.576474  0.323
2023 Yang K, Liu S, Yan H, Lu W, Shan X, Chen H, Bao C, Feng H, Liao J, Liang S, Xu L, Tang H, Yuan JX, Zhong N, Wang J. SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular calcium homeostasis and impairs pulmonary vascular endothelial cells. Signal Transduction and Targeted Therapy. 8: 276. PMID 37452066 DOI: 10.1038/s41392-023-01556-8  0.351
2023 Ayon RJ, Yuan JX. Revisiting the Role of KCNA5 in Pulmonary Arterial Hypertension. American Journal of Respiratory Cell and Molecular Biology. PMID 37201951 DOI: 10.1165/rcmb.2023-0119ED  0.352
2022 Zhu J, Yang L, Jia Y, Balistrieri A, Fraidenburg DR, Wang J, Tang H, Yuan JX. Pathogenic Mechanisms of Pulmonary Arterial Hypertension: Homeostasis Imbalance of Endothelium-Derived Relaxing and Contracting Factors. Jacc. Asia. 2: 787-802. PMID 36713766 DOI: 10.1016/j.jacasi.2022.09.010  0.364
2022 Balistrieri A, Makino A, Yuan JX. Pathophysiology and Pathogenic Mechanisms of Pulmonary Hypertension: Role of Membrane Receptors, Ion Channels and Ca Signaling. Physiological Reviews. PMID 36422993 DOI: 10.1152/physrev.00030.2021  0.408
2022 Alotaibi M, Shao J, Pauciulo MW, Nichols WC, Hemnes AR, Malhotra A, Kim NH, Yuan JX, Fernandes T, Kerr KM, Alshawabkeh L, Desai AA, Bujor AM, Lafyatis R, Watrous JD, et al. Metabolomic Profiles Differentiate Scleroderma-PAH from Idiopathic PAH and Correspond with Worsened Functional Capacity. Chest. PMID 36087794 DOI: 10.1016/j.chest.2022.08.2230  0.33
2022 Chen J, Miao J, Zhou D, Liao J, Wang Z, Lin Z, Zhang C, Luo X, Li Y, Li X, Liu S, Xing Y, Zhang Z, Zhao M, Parmisano S, ... ... Yuan JX, et al. Upregulation of mechanosensitive channel Piezo1 involved in high shear stress-induced pulmonary hypertension. Thrombosis Research. 218: 52-63. PMID 35988445 DOI: 10.1016/j.thromres.2022.08.006  0.411
2022 Zhao T, Parmisano S, Soroureddin Z, Zhao M, Yung L, Thistlethwaite PA, Makino A, Yuan JX. Mechanosensitive cation currents through TRPC6 and Piezo1 channels in human pulmonary arterial endothelial cells. American Journal of Physiology. Cell Physiology. 323: C959-C973. PMID 35968892 DOI: 10.1152/ajpcell.00313.2022  0.453
2022 Jain PP, Hosokawa S, Babicheva A, Zhao T, Chen J, Thistlethwaite PA, Makino A, Yuan JX. In Vivo and Ex Vivo Experimental Approach for Studying Functional Role of Notch in Pulmonary Vascular Disease. Methods in Molecular Biology (Clifton, N.J.). 2472: 209-220. PMID 35674903 DOI: 10.1007/978-1-0716-2201-8_17  0.367
2022 Zhang Y, Hernandez M, Gower J, Winicki N, Morataya X, Alvarez S, Yuan JX, Shyy J, Thistlethwaite PA. JAGGED-NOTCH3 signaling in vascular remodeling in pulmonary arterial hypertension. Science Translational Medicine. 14: eabl5471. PMID 35507674 DOI: 10.1126/scitranslmed.abl5471  0.418
2022 Chen J, Rodriguez M, Miao J, Liao J, Jain PP, Zhao M, Zhao T, Babicheva A, Wang Z, Parmisano S, Powers R, Matti M, Paquin C, Soroureddin Z, Shyy JY, ... ... Yuan JX, et al. Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 35318857 DOI: 10.1152/ajplung.00447.2021  0.45
2022 Breen E, Yuan JX. Targeting ATP-sensitive K Channels to Treat Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology. PMID 35238728 DOI: 10.1165/rcmb.2021-0549ED  0.488
2021 Stobdan T, Jain PP, Xiong M, Bafna V, Yuan JX, Haddad GG. Heterozygous Tropomodulin 3 mice have improved lung vascularization after chronic hypoxia. Human Molecular Genetics. PMID 34718575 DOI: 10.1093/hmg/ddab291  0.328
2021 Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, ... ... Yuan JX, et al. TRPC6, a Therapeutic Target for Pulmonary Hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 34704831 DOI: 10.1152/ajplung.00159.2021  0.475
2021 Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, ... ... Yuan JX, et al. Endothelial Upregulation of Mechanosensitive Channel Piezo1 in Pulmonary Hypertension. American Journal of Physiology. Cell Physiology. PMID 34669509 DOI: 10.1152/ajpcell.00147.2021  0.505
2021 Rodriguez M, Chen J, Jain PP, Babicheva A, Xiong M, Li J, Lai N, Zhao T, Hernandez M, Balistrieri A, Parmisano S, Simonson T, Breen E, Valdez-Jasso D, Thistlethwaite PA, ... ... Yuan JX, et al. Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells. Frontiers in Physiology. 12: 714785. PMID 34408668 DOI: 10.3389/fphys.2021.714785  0.442
2021 Liao J, Lu W, Chen Y, Duan X, Zhang C, Luo X, Lin Z, Chen J, Liu S, Yan H, Chen Y, Feng H, Zhou D, Chen X, Zhang Z, ... ... Yuan JX, et al. Upregulation of Piezo1 (Piezo Type Mechanosensitive Ion Channel Component 1) Enhances the Intracellular Free Calcium in Pulmonary Arterial Smooth Muscle Cells From Idiopathic Pulmonary Arterial Hypertension Patients. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12016. PMID 33813851 DOI: 10.1161/HYPERTENSIONAHA.120.16629  0.344
2021 Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, ... ... Yuan JX, et al. Halofuginone, a Promising Drug for Treatment of Pulmonary Hypertension. British Journal of Pharmacology. PMID 33694155 DOI: 10.1111/bph.15442  0.31
2021 Babicheva A, Makino A, Yuan JX. mTOR Signaling in Pulmonary Vascular Disease: Pathogenic Role and Therapeutic Target. International Journal of Molecular Sciences. 22. PMID 33670032 DOI: 10.3390/ijms22042144  0.37
2020 Romanoski CE, Qi X, Sangam S, Vanderpool RR, Stearman RS, Conklin A, Gonzalez-Garay M, Rischard F, Ayon RJ, Wang J, Simonson T, Babicheva A, Shi Y, Tang H, Makino A, ... ... Yuan JX, et al. Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes. Pulmonary Circulation. 10: 2045894020968531. PMID 33343881 DOI: 10.1177/2045894020968531  0.325
2020 Si R, Zhang Q, Cabrera JTO, Zheng Q, Tsuji-Hosokawa A, Watanabe M, Hosokawa S, Xiong M, Jain PP, Ashton AW, Yuan JX, Wang J, Makino A. Chronic Hypoxia Decreases Endothelial Connexin 40, Attenuates Endothelium-Dependent Hyperpolarization-Mediated Relaxation in Small Distal Pulmonary Arteries, and Leads to Pulmonary Hypertension. Journal of the American Heart Association. e018327. PMID 33307937 DOI: 10.1161/JAHA.120.018327  0.359
2020 Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, ... ... Yuan JX, et al. Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension. Pulmonary Circulation. 10: 2045894020948470. PMID 33294172 DOI: 10.1177/2045894020948470  0.337
2020 Jain PP, Hosokawa S, Xiong M, Babicheva A, Zhao T, Rodriguez M, Rahimi S, Pourhashemi K, Balistrieri F, Lai N, Malhotra A, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, ... Yuan JX, et al. Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung. Pulmonary Circulation. 10: 2045894020956592. PMID 33282184 DOI: 10.1177/2045894020956592  0.402
2020 Shen H, Zhang J, Wang C, Jain PP, Xiong M, Shi X, Lei Y, Chen S, Yin Q, Thistlethwaite PA, Wang J, Gong K, Yuan ZY, Yuan JX, Shyy JY. MDM2-Mediated Ubiquitination of ACE2 Contributes to the Development of Pulmonary Arterial Hypertension. Circulation. PMID 32755395 DOI: 10.1161/Circulationaha.120.048191  0.332
2020 Gassmann M, Cowburn A, Gu H, Li J, Rodriguez M, Babicheva A, Jain PP, Xiong M, Gassmann NN, Yuan JX, Wilkins MR, Zhao L. Hypoxia-induced pulmonary hypertension - utilising experiments of nature. British Journal of Pharmacology. PMID 32464698 DOI: 10.1111/Bph.15144  0.329
2020 Song S, Babicheva A, Zhao T, Ayon RJ, Rodriguez M, Rahimi S, Balistrieri F, Harrington A, Shyy JY, Thistlethwaite PA, Makino A, Yuan JX. Notch Enhances Ca Entry by Activating Calcium-sensing Receptors and Inhibiting Voltage-gated K Channels. American Journal of Physiology. Cell Physiology. PMID 32186932 DOI: 10.1152/Ajpcell.00487.2019  0.356
2020 Sun X, Sun BL, Babicheva A, Vanderpool R, Oita RC, Casanova N, Tang H, Gupta A, Lynn H, Gupta G, Rischard F, Sammani S, Kempf CL, Moreno-Vinasco L, Ahmed M, ... ... Yuan JX, et al. Direct eNAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling: Transcriptional Regulation by SOX and HIF2α. American Journal of Respiratory Cell and Molecular Biology. PMID 32142369 DOI: 10.1165/Rcmb.2019-0164Oc  0.362
2020 Badagliacca R, Rischard F, Papa S, Kubba S, Vanderpool R, Yuan JX, Garcia JGN, Airhart S, Poscia R, Pezzuto B, Manzi G, Miotti C, Luongo F, Scoccia G, Sciomer S, et al. Clinical implications of idiopathic pulmonary arterial hypertension phenotypes defined by cluster analysis. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. PMID 32061507 DOI: 10.1016/J.Healun.2019.12.012  0.35
2020 Goncharova EA, Simon MA, Yuan JX. mTORC1 in Pulmonary Arterial Hypertension: At the Crossroads Between Vasoconstriction and Vascular Remodeling? American Journal of Respiratory and Critical Care Medicine. PMID 31968178 DOI: 10.1164/rccm.202001-0087ED  0.348
2020 Karnes JH, Wiener HW, Schwantes-An TH, Natarajan B, Sweatt AJ, Chaturvedi A, Arora A, Batai K, Nair V, Steiner HE, Giles JB, Yu J, Hosseini M, Pauciulo MW, Lutz KA, ... ... Yuan JX, et al. Genetic Admixture and Survival in Diverse Populations with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 31916850 DOI: 10.1164/Rccm.201907-1447Oc  0.314
2020 Rahimi S, Babicheva A, Rodriguez M, Jain P, Rahimi S, Yuan JX. Upregulation of G protein‐couple receptor 68 (GPCR68) in pulmonary artery smooth muscle cells from animals and humans with pulmonary hypertension The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.09754  0.364
2020 Babicheva A, Jain P, Zhao T, Xiong M, Lai N, Makino A, Yuan JX. Decreased MicroRNA‐153 Promotes Endothelial‐to‐Mesenchymal Transition in Idiopathic Pulmonary Arterial Hypertension The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.07429  0.333
2019 Babicheva A, Ayon RJ, Zhao T, Ek Vitorin JF, Pohl NM, Yamamura A, Yamamura H, Quinton BA, Ba M, Wu L, Ravellette KS, Rahimi S, Balistrieri F, Harrington A, Vanderpool RR, ... ... Yuan JX, et al. MicroRNA-mediated Downregulation of K Channels in Pulmonary Arterial Hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31553627 DOI: 10.1152/Ajplung.00010.2019  0.343
2019 Babicheva A, Zhao T, Yuan JX. KCNK3 Channel: A New Player in the Field of Pulmonary Vascular Disease. Circulation Research. 125: 696-698. PMID 31513487 DOI: 10.1161/CIRCRESAHA.119.315758  0.377
2019 Babicheva A, Yuan JX. Endothelial Notch1 in Pulmonary Hypertension. Circulation Research. 124: 176-179. PMID 30653427 DOI: 10.1161/CIRCRESAHA.118.314496  0.315
2019 Rafikov R, Nair V, Sinari S, Babu H, Sullivan JC, Yuan JX, Desai AA, Rafikova O. GENDER DIFFERENCE IN DAMAGE MEDIATED SIGNALING CONTRIBUTES TO PULMONARY ARTERIAL HYPERTENSION. Antioxidants & Redox Signaling. PMID 30652485 DOI: 10.1089/ars.2018.7664  0.348
2019 Firth AL, Remillard CV, Platoshyn O, Fantozzi I, Ko EA, Yuan JX. Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels. Pulmonary Circulation. 1: 48-71. PMID 21927714 DOI: 10.4103/2045-8932.78103  0.437
2019 Babicheva A, Makino A, Yuan JX. MicroRNA‐181b Regulates Ca 2+ Influx by Targeting TRPC6 in PASMC from Patients with Idiopathic Pulmonary Arterial Hypertension The Faseb Journal. 33. DOI: 10.1096/fasebj.2019.33.1_supplement.lb499  0.335
2018 Tang H, Wu K, Wang J, Vinjamuri S, Gu Y, Song S, Wang Z, Zhang Q, Balistrieri A, Ayon RJ, Rischard F, Vanderpool R, Chen J, Zhou G, Desai AA, ... ... Yuan JX, et al. Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. Jacc. Basic to Translational Science. 3: 744-762. PMID 30623134 DOI: 10.1016/J.Jacbts.2018.08.009  0.358
2018 Wang Z, Yang K, Zheng Q, Zhang C, Tang H, Babicheva A, Jiang Q, Li M, Chen Y, Carr SG, Wu K, Zhang Q, Balistrieri A, Wang C, Song S, ... ... Yuan JX, et al. Divergent Changes of p53 in Pulmonary Arterial Endothelial and Smooth Muscle Cells Involved in the Development of Pulmonary Hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30358436 DOI: 10.1152/Ajplung.00538.2017  0.372
2018 Miao R, Wan J, Liu J, Yuan JX, Wang J, Xie W, Zhai Z, Wang C. Bone Marrow-Derived Endothelial Progenitor Cells Contribute to Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats via Inhibition of Store-Operated Ca Channels. Biomed Research International. 2018: 4892349. PMID 30320134 DOI: 10.1155/2018/4892349  0.405
2018 Dai J, Zhou Q, Tang H, Chen T, Li J, Raychaudhuri P, Yuan JX, Zhou G. Smooth muscle cell-specific FoxM1 controls hypoxia-induced pulmonary hypertension. Cellular Signalling. PMID 30092353 DOI: 10.1016/J.Cellsig.2018.08.003  0.38
2018 Whitaker ME, Nair V, Sinari S, Dherange P, Natarajan B, Trutter L, Brittain EL, Hemnes AR, Austin E, Patel K, Black SM, Garcia JGN, Yuan JX, Vanderpool R, Rischard F, et al. Diabetes Mellitus Associates with Increased Right Ventricular Afterload and Remodeling in Pulmonary Arterial Hypertension. The American Journal of Medicine. PMID 29421689 DOI: 10.1016/J.Amjmed.2017.12.046  0.355
2018 Song S, Carr SG, McDermott KM, Rodriguez M, Babicheva A, Balistrieri A, Ayon RJ, Wang J, Makino A, Yuan JX. STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension. Hypertension (Dallas, Tex. : 1979). PMID 29358461 DOI: 10.1161/Hypertensionaha.117.10503  0.336
2018 He X, Song S, Ayon RJ, Balisterieri A, Black SM, Makino A, Wier WG, Zang WJ, Yuan JX. Hypoxia Selectively Upregulates Cation Channels and Increases Cytosolic [Ca2+] in Pulmonary, but not Coronary, Arterial Smooth Muscle Cells. American Journal of Physiology. Cell Physiology. PMID 29351410 DOI: 10.1152/Ajpcell.00272.2017  0.331
2018 Zemskov E, Sun X, Kangath A, Lu Q, Yuan J, Black S. Cyclic stretch-induced eNOS translocation to the mitochondrion induces mitochondrial dysfunction and oxidative stress in pulmonary artery endothelial cells Free Radical Biology and Medicine. 128: S45. DOI: 10.1016/J.Freeradbiomed.2018.10.073  0.342
2017 Ranchoux B, Harvey LD, Ayon RJ, Babicheva A, Bonnet S, Chan SY, Yuan J, Perez VAJ. EXPRESS: Endothelial Dysfunction in Pulmonary Arterial Hypertension: An Evolving Landscape (2017 Grover Conference Series). Pulmonary Circulation. 2045893217752912. PMID 29283043 DOI: 10.1177/2045893217752912  0.327
2017 Wu K, Zhang Q, Wu X, Lu W, Tang H, Liang Z, Gu Y, Song S, Ayon RJ, Wang Z, McDermott KM, Balistrieri A, Wang C, Black SM, Garcia JGN, ... ... Yuan JX, et al. Chloroquine is a Potent Pulmonary Vasodilator that Attenuates Hypoxia-induced Pulmonary Hypertension. British Journal of Pharmacology. PMID 28849593 DOI: 10.1111/Bph.13990  0.377
2017 Chen J, Sysol JR, Singla S, Zhao S, Yamamura A, Valdez-Jasso D, Abbasi T, Shioura KM, Sahni S, Reddy V, Sridhar A, Gao H, Torres J, Camp SM, Tang H, ... ... Yuan JX, et al. Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and is a Therapeutic Target in Pulmonary Arterial Hypertension. Circulation. PMID 28202489 DOI: 10.1161/Circulationaha.116.024557  0.416
2016 Pullamsetti SS, Perros F, Chelladurai P, Yuan J, Stenmark K. Transcription factors, transcriptional coregulators, and epigenetic modulation in the control of pulmonary vascular cell phenotype: therapeutic implications for pulmonary hypertension (2015 Grover Conference series). Pulmonary Circulation. 6: 448-464. PMID 28090287 DOI: 10.1086/688908  0.365
2016 Song S, Ayon RJ, Yamamura A, Yamamura H, Dash S, Babicheva A, Tang H, Sun X, Cordery AG, Khalpey ZI, Black SM, Desai AA, Rischard F, McDermott KM, Garcia JG, ... ... Yuan JX, et al. Capsaicin-induced Ca2+ Signaling is Enhanced via Upregulated TRPV1 Channels in Pulmonary Artery Smooth Muscle Cells from Patients with Idiopathic PAH. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00357.2016. PMID 27979859 DOI: 10.1152/Ajplung.00357.2016  0.321
2016 Smith KA, Ayon RJ, Tang H, Makino A, Yuan JX. Calcium-Sensing Receptor Regulates Cytosolic [Ca (2+) ] and Plays a Major Role in the Development of Pulmonary Hypertension. Frontiers in Physiology. 7: 517. PMID 27867361 DOI: 10.3389/Fphys.2016.00517  0.348
2016 Boehme J, Sun X, Tormos K, Gong W, Kellner M, Datar S, Johnson Kameny R, Yuan JX, Raff GW, Fineman JR, Black SM, Maltepe E. Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00040.2016. PMID 27591215 DOI: 10.1152/ajpheart.00040.2016  0.374
2016 Song S, Ayon RJ, Yuan JX. Ryanodine Receptor-2, a Necessity for Gating Store-Operated Ca2+ Channels. Cardiovascular Research. PMID 27229459 DOI: 10.1093/Cvr/Cvw108  0.331
2016 Jiang Q, Lu W, Yang K, Hadadi C, Fu X, Chen Y, Yun X, Zhang J, Li M, Xu L, Tang H, Yuan JX, Wang J, Sun D. Sodium Tanshinone IIA Sulfonate Inhibits Hypoxia-induced Enhancement of SOCE in Pulmonary Arterial Smooth Muscle Cells via the PKG-PPARγ-TRPC Signaling Axis. American Journal of Physiology. Cell Physiology. ajpcell.00252.2015. PMID 27194472 DOI: 10.1152/ajpcell.00252.2015  0.399
2016 Tang H, Yamamura A, Yamamura H, Song S, Fraidenburg DR, Chen J, Gu Y, Pohl NM, Zhou T, Jiménez-Pérez L, Ayon RJ, Desai AA, Goltzman D, Rischard F, Khalpey ZI, ... ... Yuan JX, et al. Pathogenic Role of Calcium-sensing Receptors in the Development and Progression of Pulmonary Hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00050.2016. PMID 26968768 DOI: 10.1152/Ajplung.00050.2016  0.351
2016 Chen J, Sysol J, Shioura K, Singla S, Yamamura H, Yamamura A, Reddy V, Torres J, Sridhar A, Tang H, Yuan J, Garcia J, Machado R. ID: 72: INHIBITION OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) ATTENUATES EXPERIMENTAL PULMONARY HYPERTENSION Journal of Investigative Medicine. 64: 912.2-913. DOI: 10.1136/Jim-2016-000120.4  0.455
2015 Smith KA, Yuan JX, Schumacker PT. MicroRNAs and PARP: co-conspirators with ROS in pulmonary hypertension. Focus on "miR-223 reverses experimental pulmonary arterial hypertension". American Journal of Physiology. Cell Physiology. 309: C361-2. PMID 26201953 DOI: 10.1152/Ajpcell.00209.2015  0.341
2015 Lathen C, Zhang Y, Chow J, Singh M, Lin G, Nigam V, Ashraf YA, Yuan JX, Robbins IM, Thistlethwaite PA. Response to Letter Regarding Article, "The ERG-APLNR Axis Controls Pulmonary Venule Endothelial Proliferation in Pulmonary Veno-Occlusive Disease". Circulation. 132: e17. PMID 26169652 DOI: 10.1161/Circulationaha.114.014783  0.418
2015 Yuan JX, Morrell NW, Westcott A, Butrous G. The rise and rise of Pulmonary Circulation. Pulmonary Circulation. 5: 1-2. PMID 25992266 DOI: 10.1086/680857  0.321
2015 Tang H, Ayon RJ, Yuan JX. New insights into the pathology of pulmonary hypertension: implication of the miR-210/ISCU1/2/Fe-S axis. Embo Molecular Medicine. 7: 689-91. PMID 25851536 DOI: 10.15252/Emmm.201505160  0.346
2015 Fernandez RA, Wan J, Song S, Smith KA, Gu Y, Tauseef M, Tang H, Makino A, Mehta D, Yuan JX. Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype. American Journal of Physiology. Cell Physiology. 308: C581-93. PMID 25673771 DOI: 10.1152/ajpcell.00202.2014  0.393
2015 Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, ... ... Yuan JX, et al. Notch Activation of Ca(2+) Signaling Mediates Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology. PMID 25569851 DOI: 10.1165/Rcmb.2014-0235Oc  0.417
2015 Tang H, Chen J, Fraidenburg DR, Song S, Sysol JR, Drennan AR, Offermanns S, Ye RD, Bonini MG, Minshall RD, Garcia JG, Machado RF, Makino A, Yuan JX. Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L208-20. PMID 25416384 DOI: 10.1152/Ajplung.00242.2014  0.396
2015 Rafikova O, Sun X, Louise Meadows M, Desai AA, Yuan JX, Black SM, Rafkov R. Complex I Dysfunction Dictates Glycolytic Switch in Pulmonary Hypertensive Smooth Muscle Cells Free Radical Biology and Medicine. 87: S140. DOI: 10.1016/j.freeradbiomed.2015.10.363  0.332
2014 Chen J, Tang H, Sysol JR, Moreno-Vinasco L, Shioura KM, Chen T, Gorshkova I, Wang L, Huang LS, Usatyuk PV, Sammani S, Zhou G, Raj JU, Garcia JG, Berdyshev E, ... Yuan JX, et al. The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 190: 1032-43. PMID 25180446 DOI: 10.1164/Rccm.201401-0121Oc  0.317
2014 Wan J, Yuan JX, Miao R, Zhai Z, Zhang M, Yang Y, Wang J, Wang C. [Effects of gender on severity and pulmonary artery vascular reactivity in chronic hypoxic pulmonary hypertension in mice]. Zhonghua Yi Xue Za Zhi. 94: 1692-5. PMID 25151896 DOI: 10.3760/Cma.J.Issn.0376-2491.2014.22.004  0.33
2014 Lathen C, Zhang Y, Chow J, Singh M, Lin G, Nigam V, Ashraf YA, Yuan JX, Robbins IM, Thistlethwaite PA. ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease. Circulation. 130: 1179-91. PMID 25062690 DOI: 10.1161/Circulationaha.113.007822  0.445
2014 Yuan JX, Morrell NW, Holt C, Butrous G. The voice of pulmonary circulation. Pulmonary Circulation. 4: 1. PMID 25006415 DOI: 10.1086/675922  0.311
2014 Song S, Yamamura A, Yamamura H, Ayon RJ, Smith KA, Tang H, Makino A, Yuan JX. Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension. American Journal of Physiology. Cell Physiology. 307: C373-83. PMID 24920677 DOI: 10.1152/Ajpcell.00115.2014  0.364
2014 Zimnicka AM, Tang H, Guo Q, Kuhr FK, Oh MJ, Wan J, Chen J, Smith KA, Fraidenburg DR, Choudhury MS, Levitan I, Machado RF, Kaplan JH, Yuan JX. Upregulated copper transporters in hypoxia-induced pulmonary hypertension. Plos One. 9: e90544. PMID 24614111 DOI: 10.1371/Journal.Pone.0090544  0.334
2014 Yamamura H, Yamamura A, Ko EA, Pohl NM, Smith KA, Zeifman A, Powell FL, Thistlethwaite PA, Yuan JX. Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells. American Journal of Physiology. Cell Physiology. 306: C871-8. PMID 24573085 DOI: 10.1152/Ajpcell.00221.2013  0.351
2014 Smith KA, Yuan JX. Hypoxia-inducible factor-1α in pulmonary arterial smooth muscle cells and hypoxia-induced pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 189: 245-6. PMID 24484328 DOI: 10.1164/rccm.201312-2148ED  0.392
2014 Pohl NM, Fernandez RA, Smith KA, Yuan JX. Deacetylation of MicroRNA-124 in fibroblasts: role in pulmonary hypertension. Circulation Research. 114: 5-8. PMID 24385500 DOI: 10.1161/CIRCRESAHA.113.302838  0.325
2014 Yamamura A, Yamamura H, Yuan JX. [Enhanced Ca2+-sensing receptor function in pulmonary hypertension]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 133: 1351-9. PMID 24292183 DOI: 10.1248/yakushi.13-00228-3  0.381
2014 Guo Q, Huang JA, Yamamura A, Yamamura H, Zimnicka AM, Fernandez R, Yuan JX. Inhibition of the Ca(2+)-sensing receptor rescues pulmonary hypertension in rats and mice. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 37: 116-24. PMID 24089267 DOI: 10.1038/hr.2013.129  0.333
2013 Ogawa A, Firth AL, Ariyasu S, Yamadori I, Matsubara H, Song S, Fraidenburg DR, Yuan JX. Thrombin-mediated activation of Akt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension. Physiological Reports. 1: e00190. PMID 24744867 DOI: 10.1002/phy2.190  0.408
2013 Ayon RJ, Fernandez RA, Yuan JX. Mutant hERG channel traffic jam. Focus on "Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum". American Journal of Physiology. Cell Physiology. 305: C916-8. PMID 23986200 DOI: 10.1152/Ajpcell.00256.2013  0.418
2013 Fraidenburg D, Yuan J. Current and future therapeutic targets for pulmonary arterial hypertension. High Altitude Medicine & Biology. 14: 134-143. PMID 23795733 DOI: 10.1089/Ham.2013.1007  0.411
2013 Makino A, Firth AL, Yuan JX. Endothelial and smooth muscle cell ion channels in pulmonary vasoconstriction and vascular remodeling. Comprehensive Physiology. 1: 1555-602. PMID 23733654 DOI: 10.1002/cphy.c100023  0.466
2013 Wan J, Yamamura A, Zimnicka AM, Voiriot G, Smith KA, Tang H, Ayon RJ, Choudhury MS, Ko EA, Wang J, Wang C, Makino A, Yuan JX. Chronic hypoxia selectively enhances L- and T-type voltage-dependent Ca2+ channel activity in pulmonary artery by upregulating Cav1.2 and Cav3.2. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L154-64. PMID 23686856 DOI: 10.1152/Ajplung.00313.2012  0.428
2013 Ibe JC, Zhou Q, Chen T, Tang H, Yuan JX, Raj JU, Zhou G. Adenosine monophosphate-activated protein kinase is required for pulmonary artery smooth muscle cell survival and the development of hypoxic pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 49: 609-18. PMID 23668615 DOI: 10.1165/Rcmb.2012-0446Oc  0.316
2013 Fraidenburg DR, Yuan JX. Hungry for more: autophagy in the pathogenesis of pulmonary arterial hypertension. Circulation Research. 112: 1091-3. PMID 23580770 DOI: 10.1161/CIRCRESAHA.113.301247  0.358
2013 Ko EA, Wan J, Yamamura A, Zimnicka AM, Yamamura H, Yoo HY, Tang H, Smith KA, Sundivakkam PC, Zeifman A, Ayon RJ, Makino A, Yuan JX. Functional characterization of voltage-dependent Ca(2+) channels in mouse pulmonary arterial smooth muscle cells: divergent effect of ROS. American Journal of Physiology. Cell Physiology. 304: C1042-52. PMID 23426966 DOI: 10.1152/Ajpcell.00304.2012  0.432
2013 Yamamura A, Yamamura H, Guo Q, Zimnicka AM, Wan J, Ko EA, Smith KA, Pohl NM, Song S, Zeifman A, Makino A, Yuan JX. Dihydropyridine Ca(2+) channel blockers increase cytosolic [Ca(2+)] by activating Ca(2+)-sensing receptors in pulmonary arterial smooth muscle cells. Circulation Research. 112: 640-50. PMID 23300272 DOI: 10.1161/CIRCRESAHA.113.300897  0.402
2012 Fernandez RA, Sundivakkam P, Smith KA, Zeifman AS, Drennan AR, Yuan JX. Pathogenic role of store-operated and receptor-operated ca(2+) channels in pulmonary arterial hypertension. Journal of Signal Transduction. 2012: 951497. PMID 23056939 DOI: 10.1155/2012/951497  0.392
2012 Lang IM, Pesavento R, Bonderman D, Yuan JX. Risk factors and basic mechanisms of chronic thromboembolic pulmonary hypertension: a current understanding. The European Respiratory Journal. 41: 462-8. PMID 22700839 DOI: 10.1183/09031936.00049312  0.336
2012 Firth AL, Yuan JX. Identification of functional progenitor cells in the pulmonary vasculature. Pulmonary Circulation. 2: 84-100. PMID 22558524 DOI: 10.4103/2045-8932.94841  0.315
2012 Makino A, Wang H, Scott BT, Yuan JX, Dillmann WH. Thyroid hormone receptor-α and vascular function. American Journal of Physiology. Cell Physiology. 302: C1346-52. PMID 22322976 DOI: 10.1152/ajpcell.00292.2011  0.324
2012 Kuhr FK, Smith KA, Song MY, Levitan I, Yuan JX. New mechanisms of pulmonary arterial hypertension: role of Ca²⁺ signaling. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1546-62. PMID 22245772 DOI: 10.1152/Ajpheart.00944.2011  0.415
2012 Ogawa A, Firth AL, Smith KA, Maliakal MV, Yuan JX. PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells. American Journal of Physiology. Cell Physiology. 302: C405-11. PMID 22031597 DOI: 10.1152/ajpcell.00337.2011  0.336
2011 Yao W, Mu W, Zeifman A, Lofti M, Remillard CV, Makino A, Perkins DL, Garcia JG, Yuan JX, Zhang W. Fenfluramine-induced gene dysregulation in human pulmonary artery smooth muscle and endothelial cells. Pulmonary Circulation. 1: 405-18. PMID 22140631 DOI: 10.4103/2045-8932.87310  0.377
2011 Kuang T, Wang J, Zeifman A, Pang B, Huang X, Burg ED, Yuan JX, Wang C. Combination use of sildenafil and simvastatin increases BMPR-II signal transduction in rats with monocrotaline-mediated pulmonary hypertension. Pulmonary Circulation. 1: 111-4. PMID 22034597 DOI: 10.4103/2045-8932.78102  0.732
2011 Song MY, Makino A, Yuan JX. STIM2 Contributes to Enhanced Store-operated Ca Entry in Pulmonary Artery Smooth Muscle Cells from Patients with Idiopathic Pulmonary Arterial Hypertension. Pulmonary Circulation. 1: 84-94. PMID 21709766 DOI: 10.4103/2045-8932.78106  0.372
2011 Song MY, Makino A, Yuan JX. Role of reactive oxygen species and redox in regulating the function of transient receptor potential channels. Antioxidants & Redox Signaling. 15: 1549-65. PMID 21126186 DOI: 10.1089/Ars.2010.3648  0.358
2010 Firth AL, Mandel J, Yuan JX. Idiopathic pulmonary arterial hypertension. Disease Models & Mechanisms. 3: 268-73. PMID 20427556 DOI: 10.1242/dmm.003616  0.314
2010 Song MY, Yuan JX. Introduction to TRP channels: structure, function, and regulation. Advances in Experimental Medicine and Biology. 661: 99-108. PMID 20204725 DOI: 10.1007/978-1-60761-500-2_6  0.435
2010 Kuang T, Wang J, Pang B, Huang X, Burg ED, Yuan JX, Wang C. Combination of sildenafil and simvastatin ameliorates monocrotaline-induced pulmonary hypertension in rats. Pulmonary Pharmacology & Therapeutics. 23: 456-64. PMID 20188205 DOI: 10.1016/J.Pupt.2010.02.003  0.75
2010 Firth AL, Yao W, Remillard CV, Ogawa A, Yuan JX. Upregulation of Oct-4 isoforms in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L548-57. PMID 20139178 DOI: 10.1152/ajplung.00314.2009  0.389
2010 Burg ED, Platoshyn O, Tsigelny IF, Lozano-Ruiz B, Rana BK, Yuan JX. Tetramerization domain mutations in KCNA5 affect channel kinetics and cause abnormal trafficking patterns. American Journal of Physiology. Cell Physiology. 298: C496-509. PMID 20018952 DOI: 10.1152/Ajpcell.00464.2009  0.776
2010 Ko EA, Park WS, Firth AL, Kim N, Yuan JX, Han J. Pathophysiology of voltage-gated K+ channels in vascular smooth muscle cells: modulation by protein kinases. Progress in Biophysics and Molecular Biology. 103: 95-101. PMID 19835907 DOI: 10.1016/j.pbiomolbio.2009.10.001  0.518
2009 Li X, Zhang X, Leathers R, Makino A, Huang C, Parsa P, Macias J, Yuan JX, Jamieson SW, Thistlethwaite PA. Notch3 signaling promotes the development of pulmonary arterial hypertension. Nature Medicine. 15: 1289-97. PMID 19855400 DOI: 10.1038/nm.2021  0.407
2009 Firth AL, Platoshyn O, Brevnova EE, Burg ED, Powell F, Haddad GH, Yuan JX. Hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells. Annals of the New York Academy of Sciences. 1177: 101-11. PMID 19845612 DOI: 10.1111/J.1749-6632.2009.05040.X  0.8
2009 Ogawa A, Firth AL, Yao W, Madani MM, Kerr KM, Auger WR, Jamieson SW, Thistlethwaite PA, Yuan JX. Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L666-76. PMID 19633069 DOI: 10.1152/ajplung.90548.2008  0.373
2009 Morrell NW, Adnot S, Archer SL, Dupuis J, Jones PL, MacLean MR, McMurtry IF, Stenmark KR, Thistlethwaite PA, Weissmann N, Yuan JX, Weir EK. Cellular and molecular basis of pulmonary arterial hypertension. Journal of the American College of Cardiology. 54: S20-31. PMID 19555855 DOI: 10.1016/J.Jacc.2009.04.018  0.467
2009 Hassoun PM, Mouthon L, Barberà JA, Eddahibi S, Flores SC, Grimminger F, Jones PL, Maitland ML, Michelakis ED, Morrell NW, Newman JH, Rabinovitch M, Schermuly R, Stenmark KR, Voelkel NF, ... Yuan JX, et al. Inflammation, growth factors, and pulmonary vascular remodeling. Journal of the American College of Cardiology. 54: S10-9. PMID 19555853 DOI: 10.1016/J.Jacc.2009.04.006  0.313
2008 Ogawa A, Firth AL, Yao W, Rubin LJ, Yuan JX. Prednisolone inhibits PDGF-induced nuclear translocation of NF-kappaB in human pulmonary artery smooth muscle cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L648-57. PMID 18708631 DOI: 10.1152/ajplung.90245.2008  0.32
2008 Xu M, Remillard CV, Sachs BD, Makino A, Platoshyn O, Yao W, Dillmann WH, Akassoglou K, Yuan JX. p75 neurotrophin receptor regulates agonist-induced pulmonary vasoconstriction. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1529-38. PMID 18689502 DOI: 10.1152/Ajpheart.00115.2008  0.338
2008 Burg ED, Remillard CV, Yuan JX. Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: pharmacotherapeutic implications. British Journal of Pharmacology. 153: S99-S111. PMID 18084317 DOI: 10.1038/Sj.Bjp.0707635  0.802
2008 Xu M, Platoshyn O, Makino A, Dillmann WH, Akassoglou K, Remillard CV, Yuan JX. Characterization of agonist-induced vasoconstriction in mouse pulmonary artery. American Journal of Physiology. Heart and Circulatory Physiology. 294: H220-8. PMID 17982012 DOI: 10.1152/Ajpheart.00968.2007  0.308
2008 Remillard CV, Yuan JX. Characterization of Hemodynamics in Patients with Idiopathic and Thromboembolic Pulmonary Hypertension Clinical Medicine. Circulatory, Respiratory and Pulmonary Medicine. 2: CCRPM.S696. DOI: 10.4137/CCRPM.S696  0.311
2007 Wu W, Platoshyn O, Firth AL, Yuan JX. Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L952-9. PMID 17693484 DOI: 10.1152/ajplung.00203.2007  0.328
2007 Ko EA, Burg ED, Platoshyn O, Msefya J, Firth AL, Yuan JX. Functional characterization of voltage-gated K+ channels in mouse pulmonary artery smooth muscle cells. American Journal of Physiology. Cell Physiology. 293: C928-37. PMID 17581857 DOI: 10.1152/Ajpcell.00101.2007  0.779
2007 Platoshyn O, Yu Y, Ko EA, Remillard CV, Yuan JX. Heterogeneity of hypoxia-mediated decrease in I(K(V)) and increase in [Ca2+](cyt) in pulmonary artery smooth muscle cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L402-16. PMID 17526598 DOI: 10.1152/ajplung.00391.2006  0.428
2007 Firth AL, Remillard CV, Yuan JX. TRP channels in hypertension. Biochimica Et Biophysica Acta. 1772: 895-906. PMID 17399958 DOI: 10.1016/j.bbadis.2007.02.009  0.489
2007 Remillard CV, Tigno DD, Platoshyn O, Burg ED, Brevnova EE, Conger D, Nicholson A, Rana BK, Channick RN, Rubin LJ, O'connor DT, Yuan JX. Function of Kv1.5 channels and genetic variations of KCNA5 in patients with idiopathic pulmonary arterial hypertension. American Journal of Physiology. Cell Physiology. 292: C1837-53. PMID 17267549 DOI: 10.1152/Ajpcell.00405.2006  0.774
2007 Zhang S, Dong H, Rubin LJ, Yuan JX. Upregulation of Na+/Ca2+ exchanger contributes to the enhanced Ca2+ entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. American Journal of Physiology. Cell Physiology. 292: C2297-305. PMID 17192285 DOI: 10.1152/Ajpcell.00383.2006  0.367
2007 Sacks RS, Remillard CV, Agange N, Auger WR, Thistlethwaite PA, Yuan JX. Molecular biology of chronic thromboembolic pulmonary hypertension. Seminars in Thoracic and Cardiovascular Surgery. 18: 265-76. PMID 17185190 DOI: 10.1053/j.semtcvs.2006.09.004  0.359
2007 Murray F, Patel HH, Suda RY, Zhang S, Thistlethwaite PA, Yuan JX, Insel PA. Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L294-303. PMID 16980375 DOI: 10.1152/Ajplung.00190.2006  0.407
2006 Schach C, Xu M, Platoshyn O, Keller SH, Yuan JX. Thiol oxidation causes pulmonary vasodilation by activating K+ channels and inhibiting store-operated Ca2+ channels. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L685-98. PMID 17098807 DOI: 10.1152/ajplung.00276.2006  0.458
2006 Remillard CV, Yuan JX. TRP channels, CCE, and the pulmonary vascular smooth muscle. Microcirculation (New York, N.Y. : 1994). 13: 671-92. PMID 17085427 DOI: 10.1080/10739680600930313  0.494
2006 Fantozzi I, Platoshyn O, Wong AH, Zhang S, Remillard CV, Furtado MR, Petrauskene OV, Yuan JX. Bone morphogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pulmonary artery smooth muscle cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L993-1004. PMID 16815889 DOI: 10.1152/ajplung.00191.2005  0.541
2006 Burg ED, Remillard CV, Yuan JX. K+ channels in apoptosis. The Journal of Membrane Biology. 209: 3-20. PMID 16685597 DOI: 10.1007/S00232-005-0838-4  0.762
2006 Murray F, Insel PA, Yuan JX. Role of O(2)-sensitive K(+) and Ca(2+) channels in the regulation of the pulmonary circulation: potential role of caveolae and implications for high altitude pulmonary edema. Respiratory Physiology & Neurobiology. 151: 192-208. PMID 16364695 DOI: 10.1016/j.resp.2005.10.003  0.519
2006 Platoshyn O, Brevnova EE, Burg ED, Yu Y, Remillard CV, Yuan JX. Acute hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells. American Journal of Physiology. Cell Physiology. 290: C907-16. PMID 16236819 DOI: 10.1152/Ajpcell.00028.2005  0.8
2005 Fantozzi I, Huang W, Zhang J, Zhang S, Platoshyn O, Remillard CV, Thistlethwaite PA, Yuan JX. Divergent effects of BMP-2 on gene expression in pulmonary artery smooth muscle cells from normal subjects and patients with idiopathic pulmonary arterial hypertension. Experimental Lung Research. 31: 783-806. PMID 16368652 DOI: 10.1080/01902140500461026  0.308
2005 Remillard CV, Yuan JX. High altitude pulmonary hypertension: role of K+ and Ca2+ channels. High Altitude Medicine & Biology. 6: 133-46. PMID 16060848 DOI: 10.1089/ham.2005.6.133  0.488
2005 Platoshyn O, Remillard CV, Fantozzi I, Sison T, Yuan JX. Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells. Pflugers Archiv : European Journal of Physiology. 451: 380-387. PMID 16052353 DOI: 10.1007/s00424-005-1478-3  0.421
2005 Remillard CV, Yuan JX. ClC-3: more than just a volume-sensitive Cl- channel. British Journal of Pharmacology. 145: 1-2. PMID 15723095 DOI: 10.1038/sj.bjp.0706136  0.525
2005 Yuan JX, Rubin LJ. Pathogenesis of pulmonary arterial hypertension: the need for multiple hits. Circulation. 111: 534-8. PMID 15699271 DOI: 10.1161/01.CIR.0000156326.48823.55  0.346
2005 Mauban JR, Remillard CV, Yuan JX. Hypoxic pulmonary vasoconstriction: role of ion channels. Journal of Applied Physiology (Bethesda, Md. : 1985). 98: 415-20. PMID 15591311 DOI: 10.1152/japplphysiol.00732.2004  0.406
2004 Yu Y, Fantozzi I, Remillard CV, Landsberg JW, Kunichika N, Platoshyn O, Tigno DD, Thistlethwaite PA, Rubin LJ, Yuan JX. Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Proceedings of the National Academy of Sciences of the United States of America. 101: 13861-6. PMID 15358862 DOI: 10.1073/pnas.0405908101  0.441
2004 Kunichika N, Landsberg JW, Yu Y, Kunichika H, Thistlethwaite PA, Rubin LJ, Yuan JX. Bosentan inhibits transient receptor potential channel expression in pulmonary vascular myocytes. American Journal of Respiratory and Critical Care Medicine. 170: 1101-7. PMID 15317671 DOI: 10.1164/rccm.200312-1668OC  0.445
2004 Mandegar M, Fung YC, Huang W, Remillard CV, Rubin LJ, Yuan JX. Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension. Microvascular Research. 68: 75-103. PMID 15313118 DOI: 10.1016/j.mvr.2004.06.001  0.379
2004 Mandegar M, Thistlethwaite PA, Yuan JX. Molecular biology of primary pulmonary hypertension. Cardiology Clinics. 22: 417-29, vi. PMID 15302361 DOI: 10.1016/j.ccl.2004.04.005  0.343
2004 Zhang S, Remillard CV, Fantozzi I, Yuan JX. ATP-induced mitogenesis is mediated by cyclic AMP response element-binding protein-enhanced TRPC4 expression and activity in human pulmonary artery smooth muscle cells. American Journal of Physiology. Cell Physiology. 287: C1192-201. PMID 15229105 DOI: 10.1152/ajpcell.00158.2004  0.335
2004 Brevnova EE, Platoshyn O, Zhang S, Yuan JX. Overexpression of human KCNA5 increases IK V and enhances apoptosis. American Journal of Physiology. Cell Physiology. 287: C715-22. PMID 15140747 DOI: 10.1152/ajpcell.00050.2004  0.538
2004 Platoshyn O, Remillard CV, Fantozzi I, Mandegar M, Sison TT, Zhang S, Burg E, Yuan JX. Diversity of voltage-dependent K+ channels in human pulmonary artery smooth muscle cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L226-38. PMID 15047570 DOI: 10.1152/Ajplung.00438.2003  0.783
2004 Remillard CV, Yuan JX. Activation of K+ channels: an essential pathway in programmed cell death. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L49-67. PMID 14656699 DOI: 10.1152/ajplung.00041.2003  0.378
2003 Fantozzi I, Zhang S, Platoshyn O, Remillard CV, Cowling RT, Yuan JX. Hypoxia increases AP-1 binding activity by enhancing capacitative Ca2+ entry in human pulmonary artery endothelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1233-45. PMID 12909593 DOI: 10.1152/ajplung.00445.2002  0.326
2003 Zhang S, Fantozzi I, Tigno DD, Yi ES, Platoshyn O, Thistlethwaite PA, Kriett JM, Yung G, Rubin LJ, Yuan JX. Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L740-54. PMID 12740218 DOI: 10.1152/ajplung.00284.2002  0.385
2002 Mandegar M, Remillard CV, Yuan JX. Ion channels in pulmonary arterial hypertension. Progress in Cardiovascular Diseases. 45: 81-114. PMID 12411972 DOI: 10.1053/pcad.2002.127491  0.531
2002 Mandegar M, Yuan JX. Role of K+ channels in pulmonary hypertension. Vascular Pharmacology. 38: 25-33. PMID 12378819  0.58
2002 Platoshyn O, Zhang S, McDaniel SS, Yuan JX. Cytochrome c activates K+ channels before inducing apoptosis. American Journal of Physiology. Cell Physiology. 283: C1298-305. PMID 12225992 DOI: 10.1152/ajpcell.00592.2001  0.38
2002 Sweeney M, Yu Y, Platoshyn O, Zhang S, McDaniel SS, Yuan JX. Inhibition of endogenous TRP1 decreases capacitative Ca2+ entry and attenuates pulmonary artery smooth muscle cell proliferation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L144-55. PMID 12060571 DOI: 10.1152/ajplung.00412.2001  0.347
2002 Rao JN, Platoshyn O, Li L, Guo X, Golovina VA, Yuan JX, Wang JY. Activation of K(+) channels and increased migration of differentiated intestinal epithelial cells after wounding. American Journal of Physiology. Cell Physiology. 282: C885-98. PMID 11880277 DOI: 10.1152/ajpcell.00361.2001  0.354
2002 Krick S, Platoshyn O, Sweeney M, McDaniel SS, Zhang S, Rubin LJ, Yuan JX. Nitric oxide induces apoptosis by activating K+ channels in pulmonary vascular smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology. 282: H184-93. PMID 11748062 DOI: 10.1152/ajpheart.2002.282.1.H184  0.473
2001 Krick S, Platoshyn O, Sweeney M, Kim H, Yuan JX. Activation of K+ channels induces apoptosis in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 280: C970-9. PMID 11245614 DOI: 10.1152/AJPCELL.2001.280.4.C970  0.475
2001 Jaladanki RN, Li L, Platoshyn O, Golovina VA, Yuan JX, Wang J. Involvement of K+ channel expression and Ca2+ in migration of differentiated intestinal epithelial cells after wounding Gastroenterology. 120: A146. DOI: 10.1016/S0016-5085(08)80721-4  0.461
2000 Seiden JE, Platoshyn O, Bakst AE, McDaniel SS, Yuan JX. High K(+)-induced membrane depolarization attenuates endothelium-dependent pulmonary vasodilation. American Journal of Physiology-Lung Cellular and Molecular Physiology. 278. PMID 10666109 DOI: 10.1152/Ajplung.2000.278.2.L261  0.526
2000 Jaladanki RN, Li L, Strauch ED, Golovina VA, Yuan JX, Wang J. K+ channels regulate polyamine-dependent intestinal epithelial cell migration through Ca2+-rhoa signaling pathway Gastroenterology. 118: A675. DOI: 10.1016/S0016-5085(00)84838-6  0.483
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