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Michael D. Scofield - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Addiction, Nucleus Accumbens, Astrocytes, Nitric Oxide
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Siemsen BM, Denton AR, Parrila-Carrero J, Hooker KN, Carpenter EA, Prescot ME, Brock AG, Westphal AM, Leath MN, McFaddin JA, Jhou TC, McGinty JF, Scofield MD. Heroin Self-Administration and Extinction Increase Prelimbic Cortical Astrocyte-Synapse Proximity and Alter Dendritic Spine Morphometrics That Are Reversed by N-Acetylcysteine. Cells. 12. PMID 37508477 DOI: 10.3390/cells12141812  0.337
2021 Kruyer A, Scofield MD. Astrocytes in Addictive Disorders. Advances in Neurobiology. 26: 231-254. PMID 34888837 DOI: 10.1007/978-3-030-77375-5_10  0.363
2021 Gipson CD, Rawls S, Scofield MD, Siemsen BM, Bondy EO, Maher EE. Interactions of neuroimmune signaling and glutamate plasticity in addiction. Journal of Neuroinflammation. 18: 56. PMID 33612110 DOI: 10.1186/s12974-021-02072-8  0.308
2020 Leyrer-Jackson JM, Holter M, Overby PF, Newbern JM, Scofield MD, Olive MF, Gipson CD. Accumbens cholinergic interneurons mediate cue-induced nicotine seeking and associated glutamatergic plasticity. Eneuro. PMID 33239269 DOI: 10.1523/ENEURO.0276-20.2020  0.33
2020 Garcia-Keller C, Scofield MD, Neuhofer D, Varanasi S, Reeves MT, Hughes B, Anderson E, Richie CT, Mejias-Aponte C, Pickel J, Hope BT, Harvey BK, Cowan CW, Kalivas PW. Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33051346 DOI: 10.1523/JNEUROSCI.2666-19.2020  0.317
2020 Bobadilla AC, Dereschewitz E, Vaccaro L, Heinsbroek JA, Scofield MD, Kalivas PW. Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core. Molecular Psychiatry. PMID 32985600 DOI: 10.1038/s41380-020-00888-z  0.326
2020 Siemsen BM, Landin JD, McFaddin JA, Hooker KN, Chandler LJ, Scofield MD. Chronic intermittent ethanol and lipopolysaccharide exposure differentially alter Iba1-derived microglia morphology in the prelimbic cortex and nucleus accumbens core of male Long-Evans rats. Journal of Neuroscience Research. PMID 32621337 DOI: 10.1002/Jnr.24683  0.311
2020 Healey KL, Kibble S, Hodges S, Reissner KJ, Testen A, Wills TA, Acheson SK, Siemsen BM, McFaddin JA, Scofield MD, Swartzwelder HS. Enduring alterations in hippocampal astrocytesynaptic proximity following adolescent alcohol exposure: reversal by gabapentin. Neural Regeneration Research. 15: 1496-1501. PMID 31997814 DOI: 10.4103/1673-5374.274339  0.364
2020 Siemsen BM, McFaddin JA, Haigh K, Brock AG, Leath MN, Hooker KN, McGonegal LK, Scofield MD. Amperometric measurements of cocaine cue and novel context-evoked glutamate and nitric oxide release in the nucleus accumbens core. Journal of Neurochemistry. e14952. PMID 31901130 DOI: 10.1111/Jnc.14952  0.45
2019 Kruyer A, Scofield MD, Wood D, Reissner KJ, Kalivas PW. Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking. Biological Psychiatry. PMID 31495448 DOI: 10.1016/J.Biopsych.2019.06.026  0.406
2019 Siemsen BM, Reichel CM, Leong KC, Garcia-Keller C, Gipson CD, Spencer SM, McFaddin JA, Hooker KN, Kalivas PW, Scofield MD. Effects of Methamphetamine Self-Administration and Extinction on Astrocyte Structure and Function in the Nucleus Accumbens Core. Neuroscience. PMID 30926546 DOI: 10.1016/J.Neuroscience.2019.03.040  0.472
2018 Siemsen BM, Giannotti G, McFaddin JA, Scofield MD, McGinty JF. Biphasic effect of abstinence duration following cocaine self-administration on spine morphology and plasticity-related proteins in prelimbic cortical neurons projecting to the nucleus accumbens core. Brain Structure & Function. PMID 30498893 DOI: 10.1007/S00429-018-1805-Z  0.415
2018 Mahler SV, Brodnik ZD, Cox BM, Buchta WC, Bentzley BS, Quintanilla J, Cope ZA, Lin EC, Riedy MD, Scofield MD, Messinger J, Ruiz CM, Riegel AC, España RA, Aston-Jones G. Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30446532 DOI: 10.1523/Jneurosci.0537-18.2018  0.397
2018 Spencer S, Neuhofer D, Chioma VC, Garcia-Keller C, Schwartz DJ, Allen N, Scofield MD, Ortiz-Ithier T, Kalivas PW. A Model of Δ-Tetrahydrocannabinol Self-administration and Reinstatement That Alters Synaptic Plasticity in Nucleus Accumbens. Biological Psychiatry. PMID 29861097 DOI: 10.1016/J.Biopsych.2018.04.016  0.407
2017 Scofield MD. Exploring the Role of Astroglial Glutamate Release and Association With Synapses in Neuronal Function and Behavior. Biological Psychiatry. 84: 778-786. PMID 29258653 DOI: 10.1016/J.Biopsych.2017.10.029  0.429
2017 Bobadilla AC, Garcia-Keller C, Heinsbroek JA, Scofield M, Chareunsouk V, Monforton C, Kalivas PW. Accumbens Mechanisms for Cued Sucrose-Seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28726801 DOI: 10.1038/Npp.2017.153  0.498
2017 Scofield MD. Similitude in Methamphetamine-Induced Neuroadaptations Across Susceptibility and Chronic Drug Exposure Paradigms. Biological Psychiatry. 81. PMID 28502394 DOI: 10.1016/J.Biopsych.2017.02.1178  0.335
2017 Smith AC, Scofield MD, Heinsbroek JA, Gipson CD, Neuhofer D, Roberts-Wolfe DJ, Spencer S, Garcia-Keller C, Stankeviciute NM, Smith RJ, Allen NP, Lorang MR, Griffin WC, Boger HA, Kalivas PW. Accumbens nNOS Interneurons Regulate Cocaine Relapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 742-756. PMID 28123012 DOI: 10.1523/Jneurosci.2673-16.2016  0.473
2017 del Franco A, Powell G, Pagni B, Goenaga J, Scofield M, Gipson-Reichardt C. Role of accumbens nicotinic acetylcholine receptors in cue-induced nicotine seeking and synaptic plasticity Drug and Alcohol Dependence. 171: e52. DOI: 10.1016/J.Drugalcdep.2016.08.154  0.359
2017 Kalivas P, Scofield M, Garcia-Keller C, Heinsbroek J, Neuhoffer D. 24. Understanding Tetrapartite Synapses to Understand Relapse to Drug Use Biological Psychiatry. 81: S10-S11. DOI: 10.1016/J.Biopsych.2017.02.035  0.345
2016 Smith AC, Scofield MD, Heinsbroek JA, Gipson CD, Neuhofer D, Roberts-Wolfe DJ, Spencer S, Stankeviciute NM, Smith R, Allen NP, Lorang MR, Griffin WC, Boger HA, Kalivas PW. Accumbens nNOS interneurons regulate cocaine relapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27920147 DOI: 10.1523/JNEUROSCI.2673-16.2016  0.396
2016 Scofield MD, Heinsbroek JA, Gipson CD, Kupchik YM, Spencer S, Smith AC, Roberts-Wolfe D, Kalivas PW. The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis. Pharmacological Reviews. 68: 816-71. PMID 27363441 DOI: 10.1124/Pr.116.012484  0.46
2016 Spencer S, Scofield M, Kalivas PW. The good and bad news about glutamate in drug addiction. Journal of Psychopharmacology (Oxford, England). PMID 27353027 DOI: 10.1177/0269881116655248  0.379
2015 Scofield MD, Li H, Siemsen BM, Healey KL, Tran PK, Woronoff N, Boger HA, Kalivas PW, Reissner KJ. Cocaine Self-Administration and Extinction Leads to Reduced Glial Fibrillary Acidic Protein Expression and Morphometric Features of Astrocytes in the Nucleus Accumbens Core. Biological Psychiatry. PMID 26946381 DOI: 10.1016/J.Biopsych.2015.12.022  0.424
2015 Peters J, Scofield MD, Ghee SM, Heinsbroek JA, Reichel CM. Perirhinal Cortex mGlu5 Receptor Activation Reduces Relapse to Methamphetamine Seeking by Restoring Novelty Salience. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26365953 DOI: 10.1038/Npp.2015.283  0.353
2015 Scofield MD, Trantham-Davidson H, Schwendt M, Leong KC, Peters J, See RE, Reichel CM. Failure to Recognize Novelty after Extended Methamphetamine Self-Administration Results from Loss of Long-Term Depression in the Perirhinal Cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 25865928 DOI: 10.1038/Npp.2015.99  0.345
2015 Scofield MD, Boger HA, Smith RJ, Li H, Haydon PG, Kalivas PW. Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking. Biological Psychiatry. PMID 25861696 DOI: 10.1016/J.Biopsych.2015.02.016  0.47
2015 Smith AC, Scofield MD, Kalivas PW. The tetrapartite synapse: Extracellular matrix remodeling contributes to corticoaccumbens plasticity underlying drug addiction. Brain Research. PMID 25838241 DOI: 10.1016/J.Brainres.2015.03.027  0.373
2015 Farrand AQ, Gregory RA, Scofield MD, Helke KL, Boger HA. Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice. Neurobiology of Aging. 36: 1569-76. PMID 25577412 DOI: 10.1016/J.Neurobiolaging.2014.11.017  0.323
2015 Reissner KJ, Gipson CD, Tran PK, Knackstedt LA, Scofield MD, Kalivas PW. Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement. Addiction Biology. 20: 316-23. PMID 24612076 DOI: 10.1111/Adb.12127  0.457
2015 Gipson CD, Stankeviciute N, Kupchik Y, Scofield M, Kalivas PW. Contributions of glial glutamate transport and NMDA receptors in nicotine relapse Drug and Alcohol Dependence. 146: e122-e123. DOI: 10.1016/J.Drugalcdep.2014.09.251  0.354
2014 Smith AC, Kupchik YM, Scofield MD, Gipson CD, Wiggins A, Thomas CA, Kalivas PW. Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases. Nature Neuroscience. 17: 1655-7. PMID 25326689 DOI: 10.1038/Nn.3846  0.39
2014 Shen HW, Scofield MD, Boger H, Hensley M, Kalivas PW. Synaptic glutamate spillover due to impaired glutamate uptake mediates heroin relapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5649-57. PMID 24741055 DOI: 10.1523/Jneurosci.4564-13.2014  0.455
2014 Scofield MD, Kalivas PW. Astrocytic dysfunction and addiction: consequences of impaired glutamate homeostasis. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 20: 610-22. PMID 24496610 DOI: 10.1177/1073858413520347  0.438
2014 Kupchik YM, Scofield MD, Rice KC, Cheng K, Roques BP, Kalivas PW. Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1057-66. PMID 24431463 DOI: 10.1523/Jneurosci.4336-13.2014  0.378
2014 Stankeviciute NM, Scofield MD, Kalivas PW, Gipson CD. Rapid, transient potentiation of dendritic spines in context-induced relapse to cocaine seeking. Addiction Biology. 19: 972-4. PMID 23648005 DOI: 10.1111/Adb.12064  0.446
2013 Scofield MD, Kalivas PW. Forgiving the sins of the fathers. Nature Neuroscience. 16: 4-5. PMID 23257926 DOI: 10.1038/Nn.3288  0.341
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