Howard J. Edenberg - Publications

Affiliations: 
Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Human Development, Bioinformatics Biology

373 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Green N, Gao H, Chu X, Yuan Q, McGuire P, Lai D, Jiang G, Xuei X, Reiter J, Stevens J, Sutherland G, Goate A, Pang Z, Slesinger P, Hart RP, ... ... Edenberg HJ, et al. Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder. Biorxiv : the Preprint Server For Biology. PMID 39149227 DOI: 10.1101/2024.08.02.606355  0.31
2024 Paul SE, Baranger DAA, Johnson EC, Jackson JJ, Gorelik AJ, Miller AP, Hatoum AS, Thompson WK, Strube M, Dick DM, Kamarajan C, Kramer JR, Plawecki MH, Chan G, Anokhin AP, ... ... Edenberg HJ, et al. Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations. Psychological Medicine. 1-14. PMID 38721768 DOI: 10.1017/S003329172400076X  0.312
2024 Chen AB, Yu X, Thapa KS, Gao H, Reiter JL, Xuei X, Tsai AP, Landreth GE, Lai D, Wang Y, Foroud TM, Tischfield JA, Edenberg HJ, Liu Y. Functional 3'-UTR Variants Identify Regulatory Mechanisms Impacting Alcohol Use Disorder and Related Traits. Biorxiv : the Preprint Server For Biology. PMID 38370821 DOI: 10.1101/2024.01.31.578270  0.398
2023 Icick R, Shadrin A, Holen B, Karadag N, Parker N, O'Connell K, Frei O, Bahrami S, Høegh M, Lagerberg T, Cheng W, Seibert T, Djurovic S, Dale A, Zhou H, ... Edenberg H, et al. Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals. Research Square. PMID 38196616 DOI: 10.21203/rs.3.rs-3755915/v1  0.351
2023 Zhou H, Kember RL, Deak JD, Xu H, Toikumo S, Yuan K, Lind PA, Farajzadeh L, Wang L, Hatoum AS, Johnson J, Lee H, Mallard TT, Xu J, Johnston KJA, ... ... Edenberg HJ, et al. Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. Nature Medicine. PMID 38062264 DOI: 10.1038/s41591-023-02653-5  0.325
2023 Su J, Kuo SI, Aliev F, Rabinowitz JA, Jamil B, Chan G, Edenberg HJ, Francis M, Hesselbrock V, Kamarajan C, Kinreich S, Kramer J, Lai D, McCutcheon V, Meyers J, et al. Alcohol use polygenic risk score, social support, and alcohol use among European American and African American adults. Development and Psychopathology. 1-13. PMID 37781861 DOI: 10.1017/S0954579423001141  0.303
2023 Agrawal A, Brislin SJ, Bucholz KK, Dick D, Hart RP, Johnson EC, Meyers J, Salvatore J, Slesinger P, Almasy L, Foroud T, Goate A, Hesselbrock V, Kramer J, Kuperman S, ... ... Edenberg HJ, et al. The Collaborative Study on the Genetics of Alcoholism: Overview. Genes, Brain, and Behavior. e12864. PMID 37736010 DOI: 10.1111/gbb.12864  0.32
2023 Bountress KE, Cusack SE, Hawn SE, Grotzinger A, Bustamante D, Kirkpatrick RM, Edenberg HJ, Amstadter AB. Genetic associations between alcohol phenotypes and life satisfaction: a genomic structural equation modelling approach. Scientific Reports. 13: 13443. PMID 37596344 DOI: 10.1038/s41598-023-40199-1  0.327
2023 Dick DM, Balcke E, McCutcheon V, Francis M, Kuo S, Salvatore J, Meyers J, Bierut LJ, Schuckit M, Hesselbrock V, Edenberg HJ, Porjesz B, Kuperman S, Kramer J, Bucholz K. The collaborative study on the genetics of alcoholism: Sample and clinical data. Genes, Brain, and Behavior. e12860. PMID 37581339 DOI: 10.1111/gbb.12860  0.312
2023 Gameiro-Ros I, Popova D, Prytkova I, Pang ZP, Liu Y, Dick D, Bucholz KK, Agrawal A, Porjesz B, Goate AM, Xuei X, Kamarajan C, Tischfield JA, Edenberg HJ, Slesinger PA, et al. 5. Collaborative Study on the Genetics of Alcoholism: Functional genomics. Genes, Brain, and Behavior. e12855. PMID 37533187 DOI: 10.1111/gbb.12855  0.395
2023 Johnson EC, Salvatore JE, Lai D, Merikangas AK, Nurnberger JI, Tischfield JA, Xuei X, Kamarajan C, Wetherill L, Rice JP, Kramer JR, Kuperman S, Foroud T, Slesinger PA, Goate AM, ... ... Edenberg HJ, et al. The collaborative study on the genetics of alcoholism: Genetics. Genes, Brain, and Behavior. e12856. PMID 37387240 DOI: 10.1111/gbb.12856  0.303
2023 Saenz de Viteri S, Zhang J, Johnson EC, Barr PB, Edenberg HJ, Hesselbrock VM, Nurnberger JI, Pandey AK, Kamarajan C, Kinreich S, Tischfield JA, Plawecki MH, Kramer JR, Lai D, Kuperman S, et al. Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders. Molecular Psychiatry. PMID 37344610 DOI: 10.1038/s41380-023-02117-9  0.311
2023 Hatoum AS, Colbert SMC, Johnson EC, Huggett SB, Deak JD, Pathak G, Jennings MV, Paul SE, Karcher NR, Hansen I, Baranger DAA, Edwards A, Grotzinger A, Tucker-Drob EM, Kranzler HR, ... ... Edenberg HJ, et al. Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders. Nature Mental Health. 1: 210-223. PMID 37250466 DOI: 10.1038/s44220-023-00034-y  0.309
2023 Li R, Reiter JL, Chen AB, Chen SX, Foroud T, Edenberg HJ, Lai D, Liu Y. RNA alternative splicing impacts the risk for alcohol use disorder. Molecular Psychiatry. PMID 37217680 DOI: 10.1038/s41380-023-02111-1  0.349
2023 Zhou H, Kember RL, Deak JD, Xu H, Toikumo S, Yuan K, Lind PA, Farajzadeh L, Wang L, Hatoum AS, Johnson J, Lee H, Mallard TT, Xu J, Johnston KJA, ... ... Edenberg HJ, et al. Multi-ancestry study of the genetics of problematic alcohol use in >1 million individuals. Medrxiv : the Preprint Server For Health Sciences. PMID 36747741 DOI: 10.1101/2023.01.24.23284960  0.308
2022 Plawecki MH, Boes J, Wetherill L, Kosobud AEK, Stangl BL, Ramchandani VA, Zimmermann US, Nurnberger JI, Schuckit M, Edenberg HJ, Pandey G, Kamarajan C, Porjesz B, Foroud T, O'Connor S. Binge and high-intensity drinking-Associations with intravenous alcohol self-administration and underlying risk factors. Addiction Biology. 27: e13228. PMID 36301209 DOI: 10.1111/adb.13228  0.314
2022 Lai D, Schwantes-An TH, Abreu M, Chan G, Hesselbrock V, Kamarajan C, Liu Y, Meyers JL, Nurnberger JI, Plawecki MH, Wetherill L, Schuckit M, Zhang P, Edenberg HJ, Porjesz B, et al. Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. Translational Psychiatry. 12: 266. PMID 35790736 DOI: 10.1038/s41398-022-02029-2  0.331
2022 Bountress KE, Brick LA, Sheerin C, Grotzinger A, Bustamante D, Hawn SE, Gillespie N, Kirkpatrick RM, Kranzler H, Morey R, Edenberg HJ, Maihofer AX, Disner S, Ashley-Koch A, Peterson R, et al. Alcohol use and alcohol use disorder differ in their genetic relationships with PTSD: A genomic structural equation modelling approach. Drug and Alcohol Dependence. 234: 109430. PMID 35367939 DOI: 10.1016/j.drugalcdep.2022.109430  0.308
2021 Su J, Kuo SI, Aliev F, Chan G, Edenberg HJ, Kamarajan C, McCutcheon VV, Meyers JL, Schuckit M, Tischfield J, Dick DM. The associations between polygenic risk, sensation seeking, social support, and alcohol use in adulthood. Journal of Abnormal Psychology. 130: 525-536. PMID 34472888 DOI: 10.1037/abn0000568  0.327
2021 Kapoor M, Chao MJ, Johnson EC, Novikova G, Lai D, Meyers JL, Schulman J, Nurnberger JI, Porjesz B, Liu Y, Foroud T, Edenberg HJ, Marcora E, Agrawal A, et al. Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases. Nature Communications. 12: 5071. PMID 34417470 DOI: 10.1038/s41467-021-25392-y  0.376
2021 Mallard TT, Savage JE, Johnson EC, Huang Y, Edwards AC, Hottenga JJ, Grotzinger AD, Gustavson DE, Jennings MV, Anokhin A, Dick DM, Edenberg HJ, Kramer JR, Lai D, Meyers JL, et al. Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts. The American Journal of Psychiatry. appiajp202020091390. PMID 33985350 DOI: 10.1176/appi.ajp.2020.20091390  0.339
2020 Thapa KS, Chen AB, Lai D, Xuei X, Wetherill L, Tischfield JA, Liu Y, Edenberg HJ. Identification of Functional Genetic Variants Associated with Alcohol Dependence and Related Phenotypes Using a High-Throughput Assay. Alcoholism, Clinical and Experimental Research. PMID 33119910 DOI: 10.1111/acer.14492  0.364
2020 Lai D, Kapoor M, Wetherill L, Schwandt M, Ramchandani VA, Goldman D, Chao M, Almasy L, Bucholz K, Hart RP, Kamarajan C, Meyers JL, Nurnberger JI, Tischfield J, Edenberg HJ, et al. Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 32652861 DOI: 10.1002/Ajmg.B.32805  0.461
2020 Cho SB, Smith RL, Bucholz K, Chan G, Edenberg HJ, Hesselbrock V, Kramer J, McCutcheon VV, Nurnberger J, Schuckit M, Zang Y, Dick DM, Salvatore JE. Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk. Development and Psychopathology. 1-10. PMID 32611468 DOI: 10.1017/S0954579420000371  0.442
2020 Barr PB, Ksinan A, Su J, Johnson EC, Meyers JL, Wetherill L, Latvala A, Aliev F, Chan G, Kuperman S, Nurnberger J, Kamarajan C, Anokhin A, Agrawal A, Rose RJ, ... Edenberg HJ, et al. Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples. Translational Psychiatry. 10: 196. PMID 32555147 DOI: 10.1038/S41398-020-00865-8  0.436
2020 Zhou H, Sealock JM, Sanchez-Roige S, Clarke TK, Levey DF, Cheng Z, Li B, Polimanti R, Kember RL, Smith RV, Thygesen JH, Morgan MY, Atkinson SR, Thursz MR, Nyegaard M, ... ... Edenberg HJ, et al. Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Nature Neuroscience. PMID 32451486 DOI: 10.1038/S41593-020-0643-5  0.437
2020 Meyers JL, Zhang J, Chorlian DB, Pandey AK, Kamarajan C, Wang JC, Wetherill L, Lai D, Chao M, Chan G, Kinreich S, Kapoor M, Bertelsen S, McClintick J, Bauer L, ... ... Edenberg HJ, et al. A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior. Molecular Psychiatry. PMID 32433515 DOI: 10.1038/S41380-020-0777-6  0.78
2020 Spiegelman D, Lovato LC, Khudyakov P, Wilkens TL, Adebamowo CA, Adebamowo SN, Appel LJ, Beulens JW, Coughlin JW, Dragsted LO, Edenberg HJ, Eriksen JN, Estruch R, Grobbee DE, Gulayin PE, et al. The Moderate Alcohol and Cardiovascular Health Trial (MACH15): Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk. European Journal of Preventive Cardiology. 2047487320912376. PMID 32250171 DOI: 10.1177/2047487320912376  0.342
2020 Barr PB, Salvatore JE, Wetherill L, Anokhin A, Chan G, Edenberg HJ, Kuperman S, Meyers J, Nurnberger J, Porjesz B, Schuckit M, Dick DM. A Family-Based Genome Wide Association Study of Externalizing Behaviors. Behavior Genetics. PMID 32239439 DOI: 10.1007/S10519-020-09999-3  0.42
2020 Sarmah S, Srivastava R, McClintick JN, Janga SC, Edenberg HJ, Marrs JA. Embryonic ethanol exposure alters expression of sox2 and other early transcripts in zebrafish, producing gastrulation defects. Scientific Reports. 10: 3951. PMID 32127575 DOI: 10.1038/S41598-020-59043-X  0.317
2020 Polimanti R, Walters RK, Johnson EC, McClintick JN, Adkins AE, Adkins DE, Bacanu SA, Bierut LJ, Bigdeli TB, Brown S, Bucholz KK, Copeland WE, Costello EJ, Degenhardt L, Farrer LA, ... ... Edenberg HJ, et al. Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium. Molecular Psychiatry. PMID 32099098 DOI: 10.1038/S41380-020-0677-9  0.333
2020 Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hübel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, ... ... Edenberg HJ, et al. Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addiction Biology. e12880. PMID 32064741 DOI: 10.1111/Adb.12880  0.362
2020 Bourdon JL, Tillman R, Francis MW, Dick DM, Stephenson M, Kamarajan C, Edenberg HJ, Kramer J, Kuperman S, Bucholz KK, McCutcheon VV. Characterization of service use for alcohol problems across generations and sex in adults with alcohol use disorder. Alcoholism, Clinical and Experimental Research. PMID 31984526 DOI: 10.1111/Acer.14290  0.36
2020 Pandey G, Seay MJ, Meyers JL, Chorlian DB, Pandey AK, Kamarajan C, Ehrenberg M, Pitti D, Kinreich S, de Viteri SS, Acion L, Anokhin A, Bauer L, Chan G, Edenberg H, et al. Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity. Alcoholism, Clinical and Experimental Research. PMID 31957047 DOI: 10.1111/Acer.14280  0.398
2020 Johnson EC, Sanchez-Roige S, Acion L, Adams MJ, Bucholz KK, Chan G, Chao MJ, Chorlian DB, Dick DM, Edenberg HJ, Foroud T, Hayward C, Heron J, Hesselbrock V, Hickman M, et al. Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples. Psychological Medicine. 1-10. PMID 31955720 DOI: 10.1017/S0033291719004045  0.423
2020 McClintick JN, Thapa K, Liu Y, Xuei X, Edenberg HJ. Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome. Alcohol (Fayetteville, N.Y.). PMID 31923563 DOI: 10.1016/J.Alcohol.2019.12.004  0.317
2019 Wetherill L, Lai D, Johnson EC, Anokhin A, Bauer L, Bucholz KK, Dick DM, Hariri AR, Hesselbrock V, Kamarajan C, Kramer J, Kuperman S, Meyers JL, Nurnberger JI, Schuckit M, ... ... Edenberg HJ, et al. ERRATUM: Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. Genes, Brain, and Behavior. 18: e12608. PMID 31667958 DOI: 10.1111/Gbb.12608  0.38
2019 Salvatore JE, Barr PB, Stephenson M, Aliev F, Kuo SI, Su J, Agrawal A, Almasy L, Bierut L, Bucholz K, Chan G, Edenberg HJ, Johnson EC, McCutcheon VV, Meyers JL, et al. Sibling comparisons elucidate the associations between educational attainment polygenic scores and alcohol, nicotine and cannabis. Addiction (Abingdon, England). PMID 31659820 DOI: 10.1111/Add.14815  0.364
2019 Meyers JL, Salvatore JE, Aliev F, Johnson EC, McCutcheon VV, Su J, Kuo SI, Lai D, Wetherill L, Wang JC, Chan G, Hesselbrock V, Foroud T, Bucholz KK, Edenberg HJ, et al. Psychosocial moderation of polygenic risk for cannabis involvement: the role of trauma exposure and frequency of religious service attendance. Translational Psychiatry. 9: 269. PMID 31636251 DOI: 10.1038/S41398-019-0598-Z  0.348
2019 Meyers JL, Chorlian DB, Johnson EC, Pandey AK, Kamarajan C, Salvatore JE, Aliev F, Subbie-Saenz de Viteri S, Zhang J, Chao M, Kapoor M, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, ... ... Edenberg HJ, et al. Association of Polygenic Liability for Alcohol Dependence and EEG Connectivity in Adolescence and Young Adulthood. Brain Sciences. 9. PMID 31627376 DOI: 10.3390/Brainsci9100280  0.411
2019 Kinreich S, Meyers JL, Maron-Katz A, Kamarajan C, Pandey AK, Chorlian DB, Zhang J, Pandey G, Subbie-Saenz de Viteri S, Pitti D, Anokhin AP, Bauer L, Hesselbrock V, Schuckit MA, Edenberg HJ, et al. Predicting risk for Alcohol Use Disorder using longitudinal data with multimodal biomarkers and family history: a machine learning study. Molecular Psychiatry. PMID 31595034 DOI: 10.1038/S41380-019-0534-X  0.375
2019 Hess JL, Tylee DS, Mattheisen M, Børglum AD, Als TD, Grove J, Werge T, Mortensen PB, Mors O, Nordentoft M, Hougaard DM, Byberg-Grauholm J, Bækvad-Hansen M, ... ... Edenberg HJ, et al. A polygenic resilience score moderates the genetic risk for schizophrenia. Molecular Psychiatry. PMID 31492941 DOI: 10.1038/S41380-019-0463-8  0.303
2019 Rao X, Thapa KS, Chen AB, Lin H, Gao H, Reiter JL, Hargreaves KA, Ipe J, Lai D, Xuei X, Wang Y, Gu H, Kapoor M, Farris SP, Tischfield J, ... ... Edenberg HJ, et al. Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders. Molecular Psychiatry. PMID 31477794 DOI: 10.1038/S41380-019-0508-Z  0.448
2019 Edenberg HJ. How Much Do You Drink on Your Heavy Drinking Day? Biological Psychiatry. 86: 330-332. PMID 31416515 DOI: 10.1016/J.Biopsych.2019.06.019  0.308
2019 Lai D, Wetherill L, Kapoor M, Johnson EC, Schwandt M, Ramchandani VA, Goldman D, Joslyn G, Rao X, Liu Y, Farris S, Mayfield RD, Dick D, Hesselbrock V, Kramer J, ... ... Edenberg HJ, et al. Genome-wide association studies of the self-rating of effects of ethanol (SRE). Addiction Biology. e12800. PMID 31270906 DOI: 10.1111/Adb.12800  0.458
2019 Chan G, Kramer JR, Schuckit MA, Hesselbrock V, Bucholz KK, Edenberg HJ, Acion L, Langbehn D, McCutcheon V, Nurnberger JI, Hesselbrock M, Porjesz B, Bierut L, Marenna BC, Cookman A, et al. A Pilot Follow-Up Study of Older Alcohol Dependent COGA Adults. Alcoholism, Clinical and Experimental Research. PMID 31141183 DOI: 10.1111/Acer.14116  0.359
2019 Wetherill L, Lai D, Johnson EC, Anokhin A, Bauer L, Bucholz KK, Dick DM, Hariri AR, Hesselbrock V, Kamarajan C, Kramer J, Kuperman S, Meyers JL, Nurnberger JI, Schuckit M, ... ... Edenberg HJ, et al. Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. Genes, Brain, and Behavior. e12580. PMID 31099175 DOI: 10.1111/Gbb.12580  0.448
2019 Lai D, Wetherill L, Bertelsen S, Carey CE, Kamarajan C, Kapoor M, Meyers JL, Anokhin AP, Bennett DA, Bucholz KK, Chang KK, De Jager PL, Dick DM, Hesselbrock V, Kramer J, ... ... Edenberg HJ, et al. Genome-wide association studies of alcohol dependence, DSM-IV criterion count, and individual criteria. Genes, Brain, and Behavior. PMID 31090166 DOI: 10.1111/Gbb.12579  0.392
2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, ... ... Edenberg HJ, et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. PMID 31043756 DOI: 10.1038/S41588-019-0397-8  0.357
2019 Johnson EC, St Pierre CL, Meyers J, Aliev F, McCutcheon VV, Lai D, Dick DM, Goate AM, Kramer J, Kuperman S, Nurnberger JI, Schuckit MA, Porjesz B, Edenberg HJ, Bucholz KK, et al. The genetic relationship between alcohol consumption and aspects of problem drinking in an ascertained sample. Alcoholism, Clinical and Experimental Research. PMID 30994927 DOI: 10.1111/Acer.14064  0.43
2019 Polimanti R, Peterson RE, Ong JS, MacGregor S, Edwards AC, Clarke TK, Frank J, Gerring Z, Gillespie NA, Lind PA, Maes HH, Martin NG, Mbarek H, Medland SE, Streit F, ... ... Edenberg HJ, et al. Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium. Psychological Medicine. 1-9. PMID 30929657 DOI: 10.1017/S0033291719000667  0.406
2019 Edenberg HJ, Gelernter J, Agrawal A. Genetics of Alcoholism. Current Psychiatry Reports. 21: 26. PMID 30852706 DOI: 10.1007/S11920-019-1008-1  0.42
2019 Kapoor M, Wang JC, Farris SP, Liu Y, McClintick J, Gupta I, Meyers JL, Bertelsen S, Chao M, Nurnberger J, Tischfield J, Harari O, Zeran L, Hesselbrock V, Bauer L, ... ... Edenberg HJ, et al. Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism. Translational Psychiatry. 9: 89. PMID 30765688 DOI: 10.1038/S41398-019-0384-Y  0.796
2019 Cho SB, Su J, Kuo SI, Bucholz KK, Chan G, Edenberg HJ, McCutcheon VV, Schuckit MA, Kramer JR, Dick DM. Positive and negative reinforcement are differentially associated with alcohol consumption as a function of alcohol dependence. Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors. PMID 30667237 DOI: 10.1037/Adb0000436  0.387
2019 McClintick JN, Tischfield JA, Deng L, Kapoor M, Xuei X, Edenberg HJ. Ethanol Activates Immune Response In Lymphoblastoid Cells. Alcohol (Fayetteville, N.Y.). PMID 30639126 DOI: 10.1016/J.Alcohol.2019.01.001  0.399
2019 Meyers J, Zhang J, Chorlian D, Pandey A, Wang J, Wetherill L, Lai D, Chao M, Kapoor M, Salvatore J, Agrawal A, Edenberg H, Foround T, Goate A, Porjesz B. M97. A Genome Wide Association Study Of Interhemispheric Theta Eeg Coherence: Implications For Neural Connectivity And Alcohol Use Behavior European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.197  0.376
2019 Johnson E, Walters R, Polimanti R, McClintick J, Zhou H, Kapoor M, Hartz S, Bigdeli T, Fanous A, Meyers J, Ripke S, Gelernter J, Edenberg H, Agrawal A. 62 Genome-Wide Cross-Disorder Analyses Of Schizophrenia And Alcohol Use Disorder In More Than 350,000 Individuals Reveal Schizophrenia'S Genetic Overlap With Disordered Drinking But Not Drinks Per Week European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.203  0.759
2019 Polimanti R, Walters R, Johnson E, McClintick J, Edenberg H, Agrawal A, Gelernter J. Polygenic Risk Scores Of Risk-Tolerance And Neuroticism To Distinguish Opioid Dependence From Opioid Exposure European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.023  0.705
2019 Johnson E, Demontis D, Polimanti R, Walters R, McClintick J, Edenberg H, Gelernter J, Børglum A, Agrawal A. Genome-Wide Association Study Of Cannabis Use Disorder In European And African Ancestries European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.022  0.74
2019 Salvatore J, Barr P, Kuo SI, Su J, Almasy L, Brooks A, Bucholz K, Chao M, Edenberg H, Foroud T, Hesselbrock V, Kramer J, Nurnberger J, Kuperman S, Dick D. Sa137Social Genetics Effects On Alcohol Dependence In Marital Dyads European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.08.359  0.415
2019 Walters R, Neale B, Edenberg H, Gelernter J, Agrawal A. GENOME-WIDE META-ANALYSIS OF >14,000 ALCOHOL DEPENDENT INDIVIDUALS HIGHLIGHTS PSYCHIATRIC COMORBIDITIES European Neuropsychopharmacology. 29: S802. DOI: 10.1016/J.Euroneuro.2017.08.039  0.454
2019 Edenberg H, Goate A, Liu Y, Kapoor M, Chan G, Wetherill L, Lai D, McClintick J, Hesselbrock V, Kramer J, Kuperman S, Porjesz B, Tischfield J, Foroud T. Exome Sequencing and Genomic Studies To Better Understand Alcohol Dependence European Neuropsychopharmacology. 29: S731. DOI: 10.1016/J.Euroneuro.2017.06.054  0.796
2018 Budde M, Friedrichs S, Alliey-Rodriguez N, Ament S, Badner JA, Berrettini WH, Bloss CS, Byerley W, Cichon S, Comes AL, Coryell W, Craig DW, Degenhardt F, Edenberg HJ, Foroud T, et al. Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 30503783 DOI: 10.1016/J.Euroneuro.2018.10.005  0.385
2018 Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, ... ... Edenberg HJ, et al. Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience. 21: 1656-1669. PMID 30482948 DOI: 10.1038/S41593-018-0275-1  0.408
2018 Breuer R, Mattheisen M, Frank J, Krumm B, Treutlein J, Kassem L, Strohmaier J, Herms S, Mühleisen TW, Degenhardt F, Cichon S, Nöthen MM, Karypis G, Kelsoe J, Greenwood T, ... ... Edenberg H, et al. Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics. International Journal of Bipolar Disorders. 6: 24. PMID 30415424 DOI: 10.1186/S40345-018-0132-X  0.329
2018 Sanchez-Roige S, Palmer AA, Fontanillas P, Elson SL, Adams MJ, Howard DM, Edenberg HJ, Davies G, Crist RC, Deary IJ, McIntosh AM, Clarke TK. Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. The American Journal of Psychiatry. appiajp201818040369. PMID 30336701 DOI: 10.1176/Appi.Ajp.2018.18040369  0.452
2018 Edenberg HJ, McClintick JN. Alcohol dehydrogenases, aldehyde dehydrogenases and alcohol use disorders: a critical review. Alcoholism, Clinical and Experimental Research. PMID 30320893 DOI: 10.1111/Acer.13904  0.468
2018 Su J, Kuo SI, Bucholz KK, Edenberg HJ, Kramer JR, Schuckit M, Dick DM. Understanding Mechanisms of Genetic Risk for Adolescent Internalizing and Externalizing Problems: The Mediating Role of Parenting and Personality. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 21: 310-321. PMID 30027866 DOI: 10.1017/Thg.2018.36  0.32
2018 Schuckit MA, Smith TL, Danko G, Kramer J, Bucholz KK, McCutcheon V, Chan G, Kuperman S, Hesselbrock V, Dick DM, Hesselbrock M, Porjesz B, Edenberg HJ, Nureberger JI, Gregg M, et al. A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism. Alcoholism, Clinical and Experimental Research. PMID 29975427 DOI: 10.1111/Acer.13810  0.428
2018 Su J, Kuo SI, Aliev F, Guy MC, Derlan CL, Edenberg HJ, Nurnberger JI, Kramer JR, Bucholz KK, Salvatore JE, Dick DM. Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective. Alcoholism, Clinical and Experimental Research. PMID 29969154 DOI: 10.1111/Acer.13827  0.35
2018 Smoller JW, Andreassen OA, Edenberg HJ, Faraone SV, Glatt SJ, Kendler KS. Psychiatric genetics and the structure of psychopathology. Molecular Psychiatry. PMID 29317742 DOI: 10.1038/S41380-017-0010-4  0.305
2018 Polimanti R, Peterson R, Walters R, Ong J, McGregor S, Edwards A, Clarke T, Frank J, Gerring Z, Gillespie N, Lind P, Maes H, Mbarek H, Milaneschi Y, Streit F, ... ... Edenberg H, et al. O36. Genetic Overlap and Causality Among Major Depressive Disorder, Alcohol Dependence, and Alcohol Consumption: Findings From the Psychiatric Genomics Consortium Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.323  0.419
2017 McClintick JN, McBride WJ, Bell RL, Ding ZM, Liu Y, Xuei X, Edenberg HJ. Gene expression changes in the ventral hippocampus and medial prefrontal cortex of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking. Alcohol (Fayetteville, N.Y.). 68: 37-47. PMID 29448234 DOI: 10.1016/J.Alcohol.2017.09.002  0.394
2017 Agrawal A, Chou YL, Carey CE, Baranger DAA, Zhang B, Sherva R, Wetherill L, Kapoor M, Wang JC, Bertelsen S, Anokhin AP, Hesselbrock V, Kramer J, Lynskey MT, Meyers JL, ... ... Edenberg HJ, et al. Genome-wide association study identifies a novel locus for cannabis dependence. Molecular Psychiatry. PMID 29112194 DOI: 10.1038/Mp.2017.200  0.353
2017 Sullivan PF, Agrawal A, Bulik CM, Andreassen OA, Børglum AD, Breen G, Cichon S, Edenberg HJ, Faraone SV, Gelernter J, Mathews CA, Nievergelt CM, Smoller JW, O'Donovan MC. Psychiatric Genomics: An Update and an Agenda. The American Journal of Psychiatry. appiajp201717030283. PMID 28969442 DOI: 10.1176/Appi.Ajp.2017.17030283  0.308
2017 Kuperman S, Chan G, Kramer J, Wetherill L, Acion L, Edenberg HJ, Foroud TM, Nurnberger J, Agrawal A, Anokhin A, Brooks A, Hesselbrock V, Hesselbrock M, Schuckit M, Tischfield J, et al. A GABRA2 polymorphism improves a model for prediction of drinking initiation. Alcohol (Fayetteville, N.Y.). 63: 1-8. PMID 28847377 DOI: 10.1016/J.Alcohol.2017.03.003  0.38
2017 Andersen AM, Pietrzak RH, Kranzler HR, Ma L, Zhou H, Liu X, Kramer J, Kuperman S, Edenberg HJ, Nurnberger JI, Rice JP, Tischfield JA, Goate A, Foroud TM, Meyers JL, et al. Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence. Jama Psychiatry. PMID 28813562 DOI: 10.1001/Jamapsychiatry.2017.2269  0.366
2017 McCutcheon VV, Agrawal A, Kuo SI, Su J, Dick DM, Meyers JL, Edenberg HJ, Nurnberger JI, Kramer JR, Kuperman S, Schuckit MA, Hesselbrock VM, Brooks A, Porjesz B, Bucholz KK. Associations of Parental Alcohol Use Disorders and Parental Separation with Offspring Initiation of Alcohol, Cigarette, and Cannabis Use and Sexual Debut in High-Risk Families. Addiction (Abingdon, England). PMID 28804966 DOI: 10.1111/Add.14003  0.323
2017 Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, ... ... Edenberg HJ, et al. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Translational Psychiatry. 7: e1155. PMID 28632202 DOI: 10.1038/Tp.2017.115  0.377
2017 McCutcheon VV, Schuckit MA, Kramer JR, Chan G, Edenberg HJ, Smith TL, Bender AK, Hesselbrock V, Hesselbrock M, Bucholz KK. Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands. Addiction (Abingdon, England). PMID 28556494 DOI: 10.1111/Add.13890  0.419
2017 Cho SB, Aliev F, Clark SL, Adkins AE, Edenberg HJ, Bucholz KK, Porjesz B, Dick DM. Using Patterns of Genetic Association to Elucidate Shared Genetic Etiologies Across Psychiatric Disorders. Behavior Genetics. PMID 28343281 DOI: 10.1007/S10519-017-9844-4  0.402
2017 Agrawal A, Tillman R, Grucza RA, Nelson EC, McCutcheon VV, Few L, Conner KR, Lynskey MT, Dick DM, Edenberg HJ, Hesselbrock VM, Kramer JR, Kuperman S, Nurnberger JI, Schuckit MA, et al. Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism. Journal of Affective Disorders. 213: 96-104. PMID 28213124 DOI: 10.1016/J.Jad.2016.12.060  0.377
2017 Bucholz KK, McCutcheon VV, Agrawal A, Dick DM, Hesselbrock VM, Kramer JR, Kuperman S, Nurnberger JI, Salvatore JE, Schuckit MA, Bierut LJ, Foroud TM, Chan G, Hesselbrock M, Meyers JL, ... Edenberg HJ, et al. Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study. Alcoholism, Clinical and Experimental Research. PMID 28073157 DOI: 10.1111/Acer.13293  0.369
2017 Meyers JL, Zhang J, Wang JC, Su J, Kuo SI, Kapoor M, Wetherill L, Bertelsen S, Lai D, Salvatore JE, Kamarajan C, Chorlian D, Agrawal A, Almasy L, Bauer L, ... ... Edenberg HJ, et al. An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry. Molecular Psychiatry. PMID 28070124 DOI: 10.1038/Mp.2016.239  0.419
2016 Meyers JL, Zhang J, Manz N, Rangaswamy M, Kamarajan C, Wetherill L, Chorlian DB, Kang SJ, Bauer L, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Tischfield J, Wang JC, ... Edenberg HJ, et al. A Genome Wide Association Study of Fast Beta EEG in Families of European Ancestry. International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology. PMID 28040410 DOI: 10.1016/J.Ijpsycho.2016.12.008  0.314
2016 Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Edenberg HJ, Wetherill L, Schuckit M, Wang JC, Kuperman S, Kramer J, Tischfield JA, Porjesz B. A KCNJ6 gene polymorphism modulates theta oscillations during reward processing. International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology. PMID 27993610 DOI: 10.1016/J.Ijpsycho.2016.12.007  0.382
2016 Chorlian DB, Rangaswamy M, Manz N, Meyers JL, Kang SJ, Kamarajan C, Pandey AK, Wang JC, Wetherill L, Edenberg H, Porjesz B. Genetic correlates of the development of theta event related oscillations in adolescents and young adults. International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology. PMID 27847216 DOI: 10.1016/J.Ijpsycho.2016.11.007  0.303
2016 Breen G, Li Q, Roth BL, O'Donnell P, Didriksen M, Dolmetsch R, O'Reilly PF, Gaspar HA, Manji H, Huebel C, Kelsoe JR, Malhotra D, Bertolino A, Posthuma D, Sklar P, ... ... Edenberg HJ, et al. Translating genome-wide association findings into new therapeutics for psychiatry. Nature Neuroscience. 19: 1392-1396. PMID 27786187 DOI: 10.1038/Nn.4411  0.308
2016 Agrawal A, Edenberg HJ, Gelernter J. Meta-Analyses of Genome-Wide Association Data Hold New Promise for Addiction Genetics. Journal of Studies On Alcohol and Drugs. 77: 676-80. PMID 27588522 DOI: 10.15288/Jsad.2016.77.676  0.327
2016 Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, ... ... Edenberg HJ, et al. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Human Molecular Genetics. PMID 27329760 DOI: 10.1093/Hmg/Ddw181  0.361
2016 McClintick JN, McBride WJ, Bell RL, Ding ZM, Liu Y, Xuei X, Edenberg HJ. Gene Expression Changes in Glutamate and GABA-A Receptors, Neuropeptides, Ion Channels, and Cholesterol Synthesis in the Periaqueductal Gray Following Binge-Like Alcohol Drinking by Adolescent Alcohol-Preferring (P) Rats. Alcoholism, Clinical and Experimental Research. PMID 27061086 DOI: 10.1111/Acer.13056  0.384
2016 Kapoor M, Chou YL, Edenberg HJ, Foroud T, Martin NG, Madden PA, Wang JC, Bertelsen S, Wetherill L, Brooks A, Chan G, Hesselbrock V, Kuperman S, Medland SE, Montgomery G, et al. Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures. Translational Psychiatry. 6: e761. PMID 27003187 DOI: 10.1038/Tp.2016.27  0.424
2016 Bell RL, Hauser SR, McClintick J, Rahman S, Edenberg HJ, Szumlinski KK, McBride WJ. Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. Progress in Molecular Biology and Translational Science. 137: 41-85. PMID 26809998 DOI: 10.1016/Bs.Pmbts.2015.10.018  0.786
2015 Schwantes-An TH, Zhang J, Chen LS, Hartz SM, Culverhouse RC, Chen X, Coon H, Frank J, Kamens HM, Konte B, Kovanen L, Latvala A, Legrand LN, Maher BS, Melroy WE, ... ... Edenberg HJ, et al. Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. Behavior Genetics. PMID 26392368 DOI: 10.1007/S10519-015-9737-3  0.372
2015 Sadler B, Haller G, Edenberg H, Tischfield J, Brooks A, Kramer J, Schuckit M, Nurnberger J, Goate A. Positive Selection on Loci Associated with Drug and Alcohol Dependence. Plos One. 10: e0134393. PMID 26270548 DOI: 10.1371/Journal.Pone.0134393  0.358
2015 Fullerton JM, Koller DL, Edenberg HJ, Foroud T, Liu H, Glowinski AL, McInnis MG, Wilcox HC, Frankland A, Roberts G, Schofield PR, Mitchell PB, Nurnberger JI. Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 617-29. PMID 26178159 DOI: 10.1002/Ajmg.B.32344  0.314
2015 Kosobud AE, Wetherill L, Plawecki MH, Kareken DA, Liang T, Nurnberger JL, Windisch K, Xuei X, Edenberg HJ, Foroud TM, O'Connor SJ. Adaptation of Subjective Responses to Alcohol is Affected by an Interaction of GABRA2 Genotype and Recent Drinking. Alcoholism, Clinical and Experimental Research. 39: 1148-57. PMID 26087834 DOI: 10.1111/Acer.12749  0.43
2015 Long EC, Aliev F, Wang JC, Edenberg HJ, Nurnberger J, Hesselbrock V, Porjesz B, Dick DM. Further Analyses of Genetic Association Between GRM8 and Alcohol Dependence Symptoms Among Young Adults. Journal of Studies On Alcohol and Drugs. 76: 414-8. PMID 25978827 DOI: 10.15288/Jsad.2015.76.414  0.451
2015 Salvatore JE, Edwards AC, McClintick JN, Bigdeli TB, Adkins A, Aliev F, Edenberg HJ, Foroud T, Hesselbrock V, Kramer J, Nurnberger JI, Schuckit M, Tischfield JA, Xuei X, Dick DM. Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior. Translational Psychiatry. 5: e558. PMID 25918995 DOI: 10.1038/Tp.2015.36  0.446
2015 Salvatore JE, Aliev F, Bucholz K, Agrawal A, Hesselbrock V, Hesselbrock M, Bauer L, Kuperman S, Schuckit MA, Kramer J, Edenberg HJ, Foroud TM, Dick DM. Polygenic risk for externalizing disorders: Gene-by-development and gene-by-environment effects in adolescents and young adults. Clinical Psychological Science : a Journal of the Association For Psychological Science. 3: 189-201. PMID 25821660 DOI: 10.1177/2167702614534211  0.304
2015 Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI, Edenberg HJ, et al. Rare variants in neuronal excitability genes influence risk for bipolar disorder. Proceedings of the National Academy of Sciences of the United States of America. 112: 3576-81. PMID 25730879 DOI: 10.1073/Pnas.1424958112  0.363
2015 McClintick JN, McBride WJ, Bell RL, Ding ZM, Liu Y, Xuei X, Edenberg HJ. Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking. Pharmacology, Biochemistry, and Behavior. 129: 87-96. PMID 25542586 DOI: 10.1016/J.Pbb.2014.12.007  0.401
2015 Blednov YA, Benavidez JM, Black M, Ferguson LB, Schoenhard GL, Goate AM, Edenberg HJ, Wetherill L, Hesselbrock V, Foroud T, Harris RA. Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. Alcoholism, Clinical and Experimental Research. 39: 136-45. PMID 25516156 DOI: 10.1111/Acer.12610  0.407
2015 Aliev F, Wetherill L, Bierut L, Bucholz KK, Edenberg H, Foroud T, Dick DM. Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample. Journal of Studies On Alcohol and Drugs. 76: 38-46. PMID 25486392  0.325
2015 Wetherill L, Agrawal A, Kapoor M, Bertelsen S, Bierut LJ, Brooks A, Dick D, Hesselbrock M, Hesselbrock V, Koller DL, Le N, Nurnberger JI, Salvatore JE, Schuckit M, Tischfield JA, ... ... Edenberg HJ, et al. Association of substance dependence phenotypes in the COGA sample. Addiction Biology. 20: 617-27. PMID 24832863 DOI: 10.1111/Adb.12153  0.453
2015 Meyers JL, Shmulewitz D, Wall MM, Keyes KM, Aharonovich E, Spivak B, Weizman A, Frisch A, Edenberg HJ, Gelernter J, Grant BF, Hasin D. Childhood adversity moderates the effect of ADH1B on risk for alcohol-related phenotypes in Jewish Israeli drinkers. Addiction Biology. 20: 205-14. PMID 24164917 DOI: 10.1111/Adb.12102  0.425
2015 Aliev F, Wetherill L, Bierut L, Bucholz KK, Edenberg H, Foroud T, Dick DM. Genes Associated With Alcohol Outcomes Show Enrichment of Effects With Broad Externalizing and Impulsivity Phenotypes in an Independent Sample Journal of Studies On Alcohol and Drugs. 76: 38-46. DOI: 10.15288/Jsad.2015.76.38  0.463
2015 Edenberg HJ. SY25NEW FINDINGS ON THE GENETICS OF ALCOHOL DEPENDENCESY25-1GENOMICS OF ALCOHOLISM – FAMILY STUDIES Alcohol and Alcoholism. 50: i28.1-i28. DOI: 10.1093/Alcalc/Agv076.101  0.466
2014 Edenberg HJ, Foroud T. Genetics of alcoholism. Handbook of Clinical Neurology. 125: 561-71. PMID 25307596 DOI: 10.1016/B978-0-444-62619-6.00032-X  0.482
2014 Olfson E, Edenberg HJ, Nurnberger J, Agrawal A, Bucholz KK, Almasy LA, Chorlian D, Dick DM, Hesselbrock VM, Kramer JR, Kuperman S, Porjesz B, Schuckit MA, Tischfield JA, Wang JC, et al. An ADH1B variant and peer drinking in progression to adolescent drinking milestones: evidence of a gene-by-environment interaction. Alcoholism, Clinical and Experimental Research. 38: 2541-9. PMID 25257461 DOI: 10.1111/Acer.12524  0.414
2014 McClintick JN, Brooks AI, Deng L, Liang L, Wang JC, Kapoor M, Xuei X, Foroud T, Tischfield JA, Edenberg HJ. Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression. Alcohol (Fayetteville, N.Y.). 48: 603-10. PMID 25129674 DOI: 10.1016/J.Alcohol.2014.07.004  0.426
2014 Kilcoyne B, Shmulewitz D, Meyers JL, Aharonovich E, Greenstein E, Frisch A, Weizman A, Spivak B, Edenberg HJ, Gelernter J, Hasin DS. Alcohol consumption mediates the relationship between ADH1B and DSM-IV alcohol use disorder and criteria. Journal of Studies On Alcohol and Drugs. 75: 635-42. PMID 24988262 DOI: 10.15288/Jsad.2014.75.635  0.44
2014 Jairam S, Edenberg HJ. An enhancer-blocking element regulates the cell-specific expression of alcohol dehydrogenase 7. Gene. 547: 239-44. PMID 24971505 DOI: 10.1016/J.Gene.2014.06.047  0.367
2014 Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Almasy L, Bucholz K, Dick DM, Harari O, Xiaoling X, Hesselbrock V, Kramer J, ... ... Edenberg HJ, et al. Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. Drug and Alcohol Dependence. 142: 56-62. PMID 24962325 DOI: 10.1016/J.Drugalcdep.2014.05.023  0.429
2014 McCutcheon VV, Kramer JR, Edenberg HJ, Nurnberger JI, Kuperman S, Schuckit MA, Heath AC, Bucholz KK. Social contexts of remission from DSM-5 alcohol use disorder in a high-risk sample. Alcoholism, Clinical and Experimental Research. 38: 2015-23. PMID 24942361 DOI: 10.1111/Acer.12434  0.352
2014 Peterson RE, Maes HH, Lin P, Kramer JR, Hesselbrock VM, Bauer LO, Nurnberger JI, Edenberg HJ, Dick DM, Webb BT. On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis. Bmc Genomics. 15: 368. PMID 24884913 DOI: 10.1186/1471-2164-15-368  0.303
2014 Alam I, Padgett LR, Ichikawa S, Alkhouli M, Koller DL, Lai D, Peacock M, Xuei X, Foroud T, Edenberg HJ, Econs MJ. SIBLING family genes and bone mineral density: Association and allele-specific expression in humans Bone. 64: 166-172. PMID 24747200 DOI: 10.1016/J.Bone.2014.04.013  0.332
2014 Criado JR, Gizer IR, Edenberg HJ, Ehlers CL. CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 17: 80-8. PMID 24588897 DOI: 10.1017/Thg.2014.11  0.36
2014 Jairam S, Edenberg HJ. Single-nucleotide polymorphisms interact to affect ADH7 transcription. Alcoholism, Clinical and Experimental Research. 38: 921-9. PMID 24512552 DOI: 10.1111/Acer.12340  0.44
2014 McBride WJ, Kimpel MW, McClintick JN, Ding ZM, Edenberg HJ, Liang T, Rodd ZA, Bell RL. Changes in gene expression within the extended amygdala following binge-like alcohol drinking by adolescent alcohol-preferring (P) rats. Pharmacology, Biochemistry, and Behavior. 117: 52-60. PMID 24355552 DOI: 10.1016/J.Pbb.2013.12.009  0.413
2014 Agrawal A, Lynskey MT, Bucholz KK, Kapoor M, Almasy L, Dick DM, Edenberg HJ, Foroud T, Goate A, Hancock DB, Hartz S, Johnson EO, Hesselbrock V, Kramer JR, Kuperman S, et al. DSM-5 cannabis use disorder: a phenotypic and genomic perspective. Drug and Alcohol Dependence. 134: 362-9. PMID 24315570 DOI: 10.1016/J.Drugalcdep.2013.11.008  0.336
2014 Haller G, Kapoor M, Budde J, Xuei X, Edenberg H, Nurnberger J, Kramer J, Brooks A, Tischfield J, Almasy L, Agrawal A, Bucholz K, Rice J, Saccone N, Bierut L, et al. Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence. Human Molecular Genetics. 23: 810-9. PMID 24057674 DOI: 10.1093/Hmg/Ddt463  0.394
2014 Wetherill L, Kapoor M, Agrawal A, Bucholz K, Koller D, Bertelsen SE, Le N, Wang JC, Almasy L, Hesselbrock V, Kramer J, Nurnberger JI, Schuckit M, Tischfield JA, Xuei X, ... ... Edenberg HJ, et al. Family-based association analysis of alcohol dependence criteria and severity. Alcoholism, Clinical and Experimental Research. 38: 354-66. PMID 24015780 DOI: 10.1111/Acer.12251  0.355
2014 Dick DM, Cho SB, Latendresse SJ, Aliev F, Nurnberger JI, Edenberg HJ, Schuckit M, Hesselbrock VM, Porjesz B, Bucholz K, Wang JC, Goate A, Kramer JR, Kuperman S. Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood. Addiction Biology. 19: 1055-64. PMID 23692184 DOI: 10.1111/Adb.12066  0.396
2014 Yan J, Aliev F, Webb BT, Kendler KS, Williamson VS, Edenberg HJ, Agrawal A, Kos MZ, Almasy L, Nurnberger JI, Schuckit MA, Kramer JR, Rice JP, Kuperman S, Goate AM, et al. Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. Addiction Biology. 19: 708-21. PMID 23362995 DOI: 10.1111/Adb.12035  0.411
2014 Edenberg HJ, Foroud T. Complex Genetics of Alcoholism Neurobiology of Alcohol Dependence. 539-550. DOI: 10.1016/B978-0-12-405941-2.00026-2  0.375
2013 Wang JC, Spiegel N, Bertelsen S, Le N, McKenna N, Budde JP, Harari O, Kapoor M, Brooks A, Hancock D, Tischfield J, Foroud T, Bierut LJ, Steinbach JH, Edenberg HJ, et al. Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry. Plos One. 8: e80204. PMID 24303001 DOI: 10.1371/Journal.Pone.0080204  0.367
2013 McBride WJ, Kimpel MW, McClintick JN, Ding ZM, Hyytia P, Colombo G, Liang T, Edenberg HJ, Lumeng L, Bell RL. Gene expression within the extended amygdala of 5 pairs of rat lines selectively bred for high or low ethanol consumption. Alcohol (Fayetteville, N.Y.). 47: 517-29. PMID 24157127 DOI: 10.1016/J.Alcohol.2013.08.004  0.424
2013 Zhou Z, Karlsson C, Liang T, Xiong W, Kimura M, Tapocik JD, Yuan Q, Barbier E, Feng A, Flanigan M, Augier E, Enoch MA, Hodgkinson CA, Shen PH, Lovinger DM, ... Edenberg HJ, et al. Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America. 110: 16963-8. PMID 24082084 DOI: 10.1073/Pnas.1309839110  0.428
2013 McClintick JN, Xuei X, Tischfield JA, Goate A, Foroud T, Wetherill L, Ehringer MA, Edenberg HJ. Stress-response pathways are altered in the hippocampus of chronic alcoholics. Alcohol (Fayetteville, N.Y.). 47: 505-15. PMID 23981442 DOI: 10.1016/J.Alcohol.2013.07.002  0.467
2013 Perry BL, Pescosolido BA, Bucholz K, Edenberg H, Kramer J, Kuperman S, Schuckit MA, Nurnberger JI. Gender-specific gene-environment interaction in alcohol dependence: the impact of daily life events and GABRA2. Behavior Genetics. 43: 402-14. PMID 23974430 DOI: 10.1007/S10519-013-9607-9  0.399
2013 Chorlian DB, Rangaswamy M, Manz N, Wang JC, Dick D, Almasy L, Bauer L, Bucholz K, Foroud T, Hesselbrock V, Kang SJ, Kramer J, Kuperman S, Nurnberger J, Rice J, ... ... Edenberg HJ, et al. Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. Behavior Genetics. 43: 386-401. PMID 23963516 DOI: 10.1007/S10519-013-9604-Z  0.397
2013 Meyers JL, Shmulewitz D, Aharonovich E, Waxman R, Frisch A, Weizman A, Spivak B, Edenberg HJ, Gelernter J, Hasin DS. Alcohol-metabolizing genes and alcohol phenotypes in an Israeli household sample. Alcoholism, Clinical and Experimental Research. 37: 1872-81. PMID 23895337 DOI: 10.1111/Acer.12176  0.423
2013 Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Bucholz K, Dick D, Harari O, Hesselbrock V, Kramer J, Nurnberger JI, Rice J, ... ... Edenberg HJ, et al. A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks. Human Genetics. 132: 1141-51. PMID 23743675 DOI: 10.1007/S00439-013-1318-Z  0.459
2013 McBride WJ, Kimpel MW, McClintick JN, Ding ZM, Hauser SR, Edenberg HJ, Bell RL, Rodd ZA. Changes in gene expression within the ventral tegmental area following repeated excessive binge-like alcohol drinking by alcohol-preferring (P) rats. Alcohol (Fayetteville, N.Y.). 47: 367-80. PMID 23714385 DOI: 10.1016/J.Alcohol.2013.04.002  0.421
2013 Edenberg HJ, Foroud T. Genetics and alcoholism. Nature Reviews. Gastroenterology & Hepatology. 10: 487-94. PMID 23712313 DOI: 10.1038/Nrgastro.2013.86  0.457
2013 Zhang Z, Wang JC, Howells W, Lin P, Agrawal A, Edenberg HJ, Tischfield JA, Schuckit MA, Bierut LJ, Goate A, Rice JP. Dosage transmission disequilibrium test (dTDT) for linkage and association detection. Plos One. 8: e63526. PMID 23691058 DOI: 10.1371/Journal.Pone.0063526  0.368
2013 Kos MZ, Yan J, Dick DM, Agrawal A, Bucholz KK, Rice JP, Johnson EO, Schuckit M, Kuperman S, Kramer J, Goate AM, Tischfield JA, Foroud T, Nurnberger J, Hesselbrock V, ... ... Edenberg HJ, et al. Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. Genes, Brain, and Behavior. 12: 532-42. PMID 23607416 DOI: 10.1111/Gbb.12043  0.45
2013 Dick DM, Aliev F, Latendresse S, Porjesz B, Schuckit M, Rangaswamy M, Hesselbrock V, Edenberg H, Nurnberger J, Agrawal A, Bierut L, Wang J, Bucholz K, Kuperman S, Kramer J. How phenotype and developmental stage affect the genes we find: GABRA2 and impulsivity Twin Research and Human Genetics. 16: 661-669. PMID 23561058 DOI: 10.1017/Thg.2013.20  0.32
2013 Chen C, Cheng L, Grennan K, Pibiri F, Zhang C, Badner JA, Kelsoe JR, Greenwood TA, Nievergelt CM, Barrett TB, McKinney R, Shilling PD, Schork NJ, Smith EN, Bloss CS, ... ... Edenberg HJ, et al. Two gene co-expression modules differentiate psychotics and controls Molecular Psychiatry. 18: 1308-1314. PMID 23147385 DOI: 10.1038/Mp.2012.146  0.355
2013 Wang JC, Foroud T, Hinrichs AL, Le NX, Bertelsen S, Budde JP, Harari O, Koller DL, Wetherill L, Agrawal A, Almasy L, Brooks AI, Bucholz K, Dick D, Hesselbrock V, ... ... Edenberg HJ, et al. A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. Molecular Psychiatry. 18: 1218-24. PMID 23089632 DOI: 10.1038/Mp.2012.143  0.468
2013 Koller DL, Zheng HF, Karasik D, Yerges-Armstrong L, Liu CT, McGuigan F, Kemp JP, Giroux S, Lai D, Edenberg HJ, Peacock M, Czerwinski SA, Choh AC, McMahon G, St Pourcain B, et al. Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 547-58. PMID 23074152 DOI: 10.1002/Jbmr.1796  0.324
2013 Plawecki MH, Wetherill L, Vitvitskiy V, Kosobud A, Zimmermann US, Edenberg HJ, O'Connor S. Voluntary intravenous self-administration of alcohol detects an interaction between GABAergic manipulation and GABRG1 polymorphism genotype: a pilot study. Alcoholism, Clinical and Experimental Research. 37: E152-60. PMID 22817768 DOI: 10.1111/J.1530-0277.2012.01885.X  0.383
2013 Agrawal A, Wetherill L, Bucholz KK, Kramer J, Kuperman S, Lynskey MT, Nurnberger JI, Schuckit M, Tischfield JA, Edenberg HJ, Foroud T, Bierut LJ. Genetic influences on craving for alcohol Addictive Behaviors. 38: 1501-1508. PMID 22481050 DOI: 10.1016/J.Addbeh.2012.03.021  0.413
2013 Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ, Gershon ES, Kelsoe JR, Greenwood TA, Nievergelt CM, Chen C, McKinney R, Shilling PD, Schork NJ, Smith EN, ... ... Edenberg HJ, et al. Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. Molecular Psychiatry. 18: 340-6. PMID 22212596 DOI: 10.1038/Mp.2011.174  0.394
2013 Harari O, Wang J, Bucholz K, Edenberg HJ, Heath A, Martin NG, Pergadia ML, Montgomery G, Schrage A, Bierut LJ, Madden PF, Goate AM. Correction: Pathway Analysis of Smoking Quantity in Multiple GWAS Identifies Cholinergic and Sensory Pathways Plos One. 8. DOI: 10.1371/Annotation/21033005-E120-4364-8024-C6534B4108F6  0.335
2012 Zhao Z, Guo AY, van den Oord EJ, Aliev F, Jia P, Edenberg HJ, Riley BP, Dick DM, Bettinger JC, Davies AG, Grotewiel MS, Schuckit MA, Agrawal A, Kramer J, Nurnberger JI, et al. Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study. Bmc Genomics. 13: S16. PMID 23282140 DOI: 10.1186/1471-2164-13-S8-S16  0.466
2012 Zhou A, Breese MR, Hao Y, Edenberg HJ, Li L, Skaar TC, Liu Y. Alt Event Finder: a tool for extracting alternative splicing events from RNA-seq data. Bmc Genomics. 13: S10. PMID 23281921 DOI: 10.1186/1471-2164-13-S8-S10  0.734
2012 Harari O, Wang JC, Bucholz K, Edenberg HJ, Heath A, Martin NG, Pergadia ML, Montgomery G, Schrage A, Bierut LJ, Madden PF, Goate AM. Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways. Plos One. 7: e50913. PMID 23227220 DOI: 10.1371/Journal.Pone.0050913  0.353
2012 Edenberg HJ. Genes contributing to the development of alcoholism: an overview. Alcohol Research : Current Reviews. 34: 336-8. PMID 23134049  0.377
2012 Nissen S, Liang S, Shehktman T, Kelsoe JR, Greenwood TA, Nievergelt CM, McKinney R, Shilling PD, Smith EN, Schork NJ, Bloss CS, Nurnberger JI, Edenberg HJ, Foroud T, et al. Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 941-50. PMID 23038240 DOI: 10.1002/Ajmg.B.32099  0.358
2012 Meier S, Mattheisen M, Vassos E, Strohmaier J, Treutlein J, Josef F, Breuer R, Degenhardt F, Mühleisen TW, Müller-Myhsok B, Steffens M, Schmael C, McMahon FJ, Nöthen MM, ... ... Edenberg HJ, et al. Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1. Translational Psychiatry. 2: e165. PMID 23010768 DOI: 10.1038/Tp.2012.81  0.343
2012 Lin P, Hartz SM, Wang JC, Agrawal A, Zhang TX, McKenna N, Bucholz K, Brooks AI, Tischfield JA, Edenberg HJ, Hesselbrock VM, Kramer JR, Kuperman S, Schuckit MA, Goate AM, et al. Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. Alcoholism, Clinical and Experimental Research. 36: 1512-8. PMID 22702843 DOI: 10.1111/J.1530-0277.2012.01758.X  0.439
2012 Teng M, Ichikawa S, Padgett LR, Wang Y, Mort M, Cooper DN, Koller DL, Foroud T, Edenberg HJ, Econs MJ, Liu Y. regSNPs: a strategy for prioritizing regulatory single nucleotide substitutions. Bioinformatics (Oxford, England). 28: 1879-86. PMID 22611130 DOI: 10.1093/Bioinformatics/Bts275  0.333
2012 McBride WJ, Kimpel MW, McClintick JN, Ding ZM, Hyytia P, Colombo G, Edenberg HJ, Lumeng L, Bell RL. Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumption. Pharmacology, Biochemistry, and Behavior. 102: 275-85. PMID 22579914 DOI: 10.1016/J.Pbb.2012.04.016  0.426
2012 Kang SJ, Rangaswamy M, Manz N, Wang JC, Wetherill L, Hinrichs T, Almasy L, Brooks A, Chorlian DB, Dick D, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Rice J, ... ... Edenberg HJ, et al. Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. Genes, Brain, and Behavior. 11: 712-9. PMID 22554406 DOI: 10.1111/J.1601-183X.2012.00803.X  0.436
2012 Rice JP, Hartz SM, Agrawal A, Almasy L, Bennett S, Breslau N, Bucholz KK, Doheny KF, Edenberg HJ, Goate AM, Hesselbrock V, Howells WB, Johnson EO, Kramer J, Krueger RF, et al. CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results. Addiction (Abingdon, England). 107: 2019-28. PMID 22524403 DOI: 10.1111/J.1360-0443.2012.03922.X  0.327
2012 Kapoor M, Wang JC, Bertelsen S, Bucholz K, Budde JP, Hinrichs A, Agrawal A, Brooks A, Chorlian D, Dick D, Hesselbrock V, Foroud T, Kramer J, Kuperman S, Manz N, ... ... Edenberg HJ, et al. Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking. Plos One. 7: e33513. PMID 22438940 DOI: 10.1371/Journal.Pone.0033513  0.366
2012 Derringer J, Krueger RF, Dick DM, Aliev F, Grucza RA, Saccone S, Agrawal A, Edenberg HJ, Goate AM, Hesselbrock VM, Kramer JR, Lin P, Neuman RJ, Nurnberger JI, Rice JP, et al. The aggregate effect of dopamine genes on dependence symptoms among cocaine users: cross-validation of a candidate system scoring approach. Behavior Genetics. 42: 626-35. PMID 22358648 DOI: 10.1007/S10519-012-9531-4  0.316
2012 Agrawal A, Freedman ND, Cheng YC, Lin P, Shaffer JR, Sun Q, Taylor K, Yaspan B, Cole JW, Cornelis MC, DeSensi RS, Fitzpatrick A, Heiss G, Kang JH, O'Connell J, ... ... Edenberg HJ, et al. Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges. The American Journal of Clinical Nutrition. 95: 539-47. PMID 22301922 DOI: 10.3945/Ajcn.111.015545  0.442
2012 Pochareddy S, Edenberg HJ. Chronic alcohol exposure alters gene expression in HepG2 cells. Alcoholism, Clinical and Experimental Research. 36: 1021-33. PMID 22150570 DOI: 10.1111/J.1530-0277.2011.01677.X  0.414
2012 Edwards AC, Aliev F, Bierut LJ, Bucholz KK, Edenberg H, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Schuckit MA, Porjesz B, Dick DM. Genome-wide association study of comorbid depressive syndrome and alcohol dependence. Psychiatric Genetics. 22: 31-41. PMID 22064162 DOI: 10.1097/Ypg.0B013E32834Acd07  0.409
2012 Bierut LJ, Goate AM, Breslau N, Johnson EO, Bertelsen S, Fox L, Agrawal A, Bucholz KK, Grucza R, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Porjesz B, Saccone NL, ... ... Edenberg HJ, et al. ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry. Molecular Psychiatry. 17: 445-50. PMID 21968928 DOI: 10.1038/Mp.2011.124  0.439
2012 Badner JA, Koller D, Foroud T, Edenberg H, Nurnberger JI, Zandi PP, Willour VL, McMahon FJ, Potash JB, Hamshere M, Grozeva D, Green E, Kirov G, Jones I, Jones L, et al. Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms. Molecular Psychiatry. 17: 818-26. PMID 21769101 DOI: 10.1038/Mp.2011.89  0.338
2011 Le-Niculescu H, Case NJ, Hulvershorn L, Patel SD, Bowker D, Gupta J, Bell R, Edenberg HJ, Tsuang MT, Kuczenski R, Geyer MA, Rodd ZA, Niculescu AB. Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism. Translational Psychiatry. 1: e4. PMID 22832392 DOI: 10.1038/Tp.2011.1  0.426
2011 Teng M, Wang Y, Wang G, Jung J, Edenberg HJ, Sanford JR, Liu Y. Prioritizing single-nucleotide variations that potentially regulate alternative splicing. Bmc Proceedings. 5: S40. PMID 22373210 DOI: 10.1186/1753-6561-5-S9-S40  0.344
2011 Sklar P, Ripke S, Scott LJ, Andreassen OA, Cichon S, Craddock N, Edenberg HJ, Nurnberger JI, Rietschel M, Blackwood D, Corvin A, Flickinger M, Guan W, Mattingsdal M, McQuillin A, et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 Nature Genetics. 43: 977-985. PMID 21926972 DOI: 10.1038/Ng.943  0.329
2011 Edenberg HJ. Common and rare variants in alcohol dependence. Biological Psychiatry. 70: 498-9. PMID 21864733 DOI: 10.1016/J.Biopsych.2011.07.007  0.486
2011 Smith EN, Koller DL, Panganiban C, Szelinger S, Zhang P, Badner JA, Barrett TB, Berrettini WH, Bloss CS, Byerley W, Coryell W, Edenberg HJ, Foroud T, Gershon ES, Greenwood TA, et al. Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. Plos Genetics. 7: e1002134. PMID 21738484 DOI: 10.1371/Journal.Pgen.1002134  0.383
2011 Agrawal A, Lynskey MT, Hinrichs A, Grucza R, Saccone SF, Krueger R, Neuman R, Howells W, Fisher S, Fox L, Cloninger R, Dick DM, Doheny KF, Edenberg HJ, Goate AM, et al. A genome-wide association study of DSM-IV cannabis dependence. Addiction Biology. 16: 514-8. PMID 21668797 DOI: 10.1111/J.1369-1600.2010.00255.X  0.358
2011 Gizer IR, Edenberg HJ, Gilder DA, Wilhelmsen KC, Ehlers CL. Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a Native American community sample. Alcoholism, Clinical and Experimental Research. 35: 2008-18. PMID 21635275 DOI: 10.1111/J.1530-0277.2011.01552.X  0.438
2011 McCutcheon VV, Agrawal A, Heath AC, Edenberg HJ, Hesselbrock VM, Schuckit MA, Kramer JR, Bucholz KK. Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol. Alcoholism, Clinical and Experimental Research. 35: 1985-93. PMID 21631541 DOI: 10.1111/J.1530-0277.2011.01550.X  0.4
2011 Maher BS, Vladimirov VI, Latendresse SJ, Thiselton DL, McNamee R, Kang M, Bigdeli TB, Chen X, Riley BP, Hettema JM, Chilcoat H, Heidbreder C, Muglia P, Murrelle EL, Dick DM, ... ... Edenberg HJ, et al. The AVPR1A gene and substance use disorders: association, replication, and functional evidence. Biological Psychiatry. 70: 519-27. PMID 21514569 DOI: 10.1016/J.Biopsych.2011.02.023  0.349
2011 Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, ... ... Edenberg HJ, et al. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America. 108: 7119-24. PMID 21471458 DOI: 10.1073/Pnas.1017288108  0.478
2011 Zhou FC, Zhao Q, Liu Y, Goodlett CR, Liang T, McClintick JN, Edenberg HJ, Li L. Alteration of gene expression by alcohol exposure at early neurulation. Bmc Genomics. 12: 124. PMID 21338521 DOI: 10.1186/1471-2164-12-124  0.423
2011 Derringer J, Krueger RF, Manz N, Porjesz B, Almasy L, Bookman E, Edenberg HJ, Kramer JR, Tischfield JA, Bierut LJ. Nonreplication of an association of SGIP1 SNPs with alcohol dependence and resting theta EEG power. Psychiatric Genetics. 21: 265-6. PMID 21317682 DOI: 10.1097/Ypg.0B013E32834371Fd  0.399
2011 Hartz SM, Lin P, Edenberg HJ, Xuei X, Rochberg N, Saccone S, Berrettini W, Nelson E, Nurnberger J, Bierut LJ, Rice JP. Genetic association of bipolar disorder with the β(3) nicotinic receptor subunit gene. Psychiatric Genetics. 21: 77-84. PMID 21191315 DOI: 10.1097/Ypg.0B013E32834135Eb  0.305
2011 Zlojutro M, Manz N, Rangaswamy M, Xuei X, Flury-Wetherill L, Koller D, Bierut LJ, Goate A, Hesselbrock V, Kuperman S, Nurnberger J, Rice JP, Schuckit MA, Foroud T, Edenberg HJ, et al. Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 44-58. PMID 21184583 DOI: 10.1002/Ajmg.B.31136  0.47
2011 Pochareddy S, Edenberg HJ. Variation in the ADH1B proximal promoter affects expression. Chemico-Biological Interactions. 191: 38-41. PMID 21168396 DOI: 10.1016/J.Cbi.2010.12.007  0.424
2011 Dick DM, Aliev F, Krueger RF, Edwards A, Agrawal A, Lynskey M, Lin P, Schuckit M, Hesselbrock V, Nurnberger J, Almasy L, Porjesz B, Edenberg HJ, Bucholz K, Kramer J, et al. Genome-wide association study of conduct disorder symptomatology. Molecular Psychiatry. 16: 800-8. PMID 20585324 DOI: 10.1038/Mp.2010.73  0.315
2011 Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, ... ... Edenberg HJ, et al. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (Proceedings of the National Academy Sciences of the United States of America (2011) 108, 17, (7119-7124)) Proceedings of the National Academy of Sciences of the United States of America. 108: 9316. DOI: 10.1073/Pnas.1106917108  0.445
2010 Foroud T, Edenberg HJ, Crabbe JC. Genetic research: who is at risk for alcoholism. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 33: 64-75. PMID 23579937  0.372
2010 Naguleswaran A, Elias EV, McClintick J, Edenberg HJ, Sullivan WJ. Toxoplasma gondii lysine acetyltransferase GCN5-A functions in the cellular response to alkaline stress and expression of cyst genes. Plos Pathogens. 6: e1001232. PMID 21179246 DOI: 10.1371/Journal.Ppat.1001232  0.74
2010 Derringer J, Krueger RF, Dick DM, Saccone S, Grucza RA, Agrawal A, Lin P, Almasy L, Edenberg HJ, Foroud T, Nurnberger JI, Hesselbrock VM, Kramer JR, Kuperman S, Porjesz B, et al. Predicting sensation seeking from dopamine genes. A candidate-system approach. Psychological Science. 21: 1282-90. PMID 20732903 DOI: 10.1177/0956797610380699  0.336
2010 Laurie CC, Doheny KF, Mirel DB, Pugh EW, Bierut LJ, Bhangale T, Boehm F, Caporaso NE, Cornelis MC, Edenberg HJ, Gabriel SB, Harris EL, Hu FB, Jacobs KB, Kraft P, et al. Quality control and quality assurance in genotypic data for genome-wide association studies. Genetic Epidemiology. 34: 591-602. PMID 20718045 DOI: 10.1002/Gepi.20516  0.329
2010 Kranzler HR, Edenberg HJ. Pharmacogenetics of alcohol and alcohol dependence treatment. Current Pharmaceutical Design. 16: 2141-8. PMID 20482509 DOI: 10.2174/138161210791516387  0.438
2010 Dick DM, Meyers J, Aliev F, Nurnberger J, Kramer J, Kuperman S, Porjesz B, Tischfield J, Edenberg HJ, Foroud T, Schuckit M, Goate A, Hesselbrock V, Bierut L. Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153: 1179-1188. PMID 20468071 DOI: 10.1002/Ajmg.B.31089  0.442
2010 Chen AC, Manz N, Tang Y, Rangaswamy M, Almasy L, Kuperman S, Nurnberger J, O'Connor SJ, Edenberg HJ, Schuckit MA, Tischfield J, Foroud T, Bierut LJ, Rohrbaugh J, Rice JP, et al. Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence. Alcoholism, Clinical and Experimental Research. 34: 988-96. PMID 20374216 DOI: 10.1111/J.1530-0277.2010.01173.X  0.476
2010 Pochareddy S, Edenberg HJ. Identification of a FOXA-dependent enhancer of human alcohol dehydrogenase 4 (ADH4). Gene. 460: 1-7. PMID 20363298 DOI: 10.1016/J.Gene.2010.03.013  0.383
2010 Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, et al. A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. Human Molecular Genetics. 19: 2497-506. PMID 20332099 DOI: 10.1093/Hmg/Ddq112  0.432
2010 Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, ... Edenberg HJ, et al. A genome-wide association study of alcohol dependence. Proceedings of the National Academy of Sciences of the United States of America. 107: 5082-7. PMID 20202923 DOI: 10.1073/Pnas.0911109107  0.457
2010 Edenberg HJ, Koller DL, Xuei X, Wetherill L, McClintick JN, Almasy L, Bierut LJ, Bucholz KK, Goate A, Aliev F, Dick D, Hesselbrock V, Hinrichs A, Kramer J, Kuperman S, et al. Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcoholism, Clinical and Experimental Research. 34: 840-52. PMID 20201924 DOI: 10.1111/J.1530-0277.2010.01156.X  0.492
2010 Alam I, Carr LG, Liang T, Liu Y, Edenberg HJ, Econs MJ, Turner CH. Identification of genes influencing skeletal phenotypes in congenic P/NP rats. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1314-25. PMID 20200994 DOI: 10.1002/Jbmr.8  0.333
2010 Liang T, Kimpel MW, McClintick JN, Skillman AR, McCall K, Edenberg HJ, Carr LG. Candidate genes for alcohol preference identified by expression profiling in alcohol-preferring and -nonpreferring reciprocal congenic rats. Genome Biology. 11: R11. PMID 20128895 DOI: 10.1186/Gb-2010-11-2-R11  0.419
2010 McBride WJ, Kimpel MW, Schultz JA, McClintick JN, Edenberg HJ, Bell RL. Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking. Alcohol (Fayetteville, N.Y.). 44: 171-83. PMID 20116196 DOI: 10.1016/J.Alcohol.2009.12.001  0.398
2010 Kramer JR, Chan G, Hesselbrock VM, Kuperman S, Bucholz KK, Edenberg HJ, Schuckit MA, Nurnberger JI, Foroud T, Dick DM, Bierut LJ, Porjesz B. A principal components analysis of the abbreviated Desires for Alcohol Questionnaire (DAQ). Journal of Studies On Alcohol and Drugs. 71: 150-5. PMID 20105425 DOI: 10.15288/Jsad.2010.71.150  0.389
2010 Alam I, Sun Q, Koller DL, Liu L, Liu Y, Edenberg HJ, Foroud T, Turner CH. Genes influencing spinal bone mineral density in inbred F344, LEW, COP, and DA rats. Functional & Integrative Genomics. 10: 63-72. PMID 19841953 DOI: 10.1007/S10142-009-0147-6  0.306
2010 Xuei X, Flury-Wetherill L, Dick D, Goate A, Tischfield J, Nurnberger J, Schuckit M, Kramer J, Kuperman S, Hesselbrock V, Porjesz B, Foroud T, Edenberg HJ. GABRR1 and GABRR2, encoding the GABA-A receptor subunits ρ1 and ρ2, are associated with alcohol dependence American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153: 418-427. PMID 19536785 DOI: 10.1002/Ajmg.B.30995  0.414
2010 Cavazos-Rehg PA, Spitznagel EL, Bucholz KK, Nurnberger J, Edenberg HJ, Kramer JR, Kuperman S, Hesselbrock V, Bierut LJ. Predictors of sexual debut at age 16 or younger. Archives of Sexual Behavior. 39: 664-73. PMID 18846417 DOI: 10.1007/S10508-008-9397-Y  0.37
2010 Herbert B, Chanoux RA, Liu Y, Baenziger PH, Goswami CP, McClintick JN, Edenberg HJ, Pennington RE, Lipkin SM, Kopelovich L. A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers. Oncotarget. 1: 405-422. DOI: 10.18632/Oncotarget.175  0.302
2009 Edenberg HJ, Liu Y. Laboratory methods for high-throughput genotyping. Cold Spring Harbor Protocols. 2009: pdb.top62. PMID 20150074 DOI: 10.1101/Pdb.Top62  0.338
2009 Bell RL, Kimpel MW, McClintick JN, Strother WN, Carr LG, Liang T, Rodd ZA, Mayfield RD, Edenberg HJ, McBride WJ. Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption. Pharmacology, Biochemistry, and Behavior. 94: 131-47. PMID 19666046 DOI: 10.1016/J.Pbb.2009.07.019  0.404
2009 Kramer JR, Chan G, Kuperman S, Bucholz KK, Edenberg HJ, Schuckit MA, Polgreen LA, Kapp ES, Hesselbrock VM, Nurnberger JI, Bierut LJ. A comparison of diagnoses obtained from in-person and telephone interviews, using the semi-structured assessment for the genetics of alcoholism (SSAGA). Journal of Studies On Alcohol and Drugs. 70: 623-7. PMID 19515304 DOI: 10.15288/Jsad.2009.70.623  0.38
2009 Smith EN, Bloss CS, Badner JA, Barrett T, Belmonte PL, Berrettini W, Byerley W, Coryell W, Craig D, Edenberg HJ, Eskin E, Foroud T, Gershon E, Greenwood TA, Hipolito M, et al. Genome-wide association study of bipolar disorder in European American and African American individuals. Molecular Psychiatry. 14: 755-63. PMID 19488044 DOI: 10.1038/Mp.2009.43  0.329
2009 Alam I, Sun Q, Koller DL, Liu L, Liu Y, Edenberg HJ, Li J, Foroud T, Turner CH. Differentially expressed genes strongly correlated with femur strength in rats. Genomics. 94: 257-62. PMID 19482074 DOI: 10.1016/J.Ygeno.2009.05.008  0.319
2009 Hurley JH, Ballard CJ, Edenberg HJ. Altering the relative abundance of GABA A receptor subunits changes GABA- and ethanol-responses in Xenopus oocytes. Alcoholism, Clinical and Experimental Research. 33: 1089-96. PMID 19382902 DOI: 10.1111/J.1530-0277.2009.00930.X  0.379
2009 Saccone SF, Bierut LJ, Chesler EJ, Kalivas PW, Lerman C, Saccone NL, Uhl GR, Li CY, Philip VM, Edenberg HJ, Sherry ST, Feolo M, Moyzis RK, Rutter JL. Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm. Plos One. 4: e5225. PMID 19381300 DOI: 10.1371/Journal.Pone.0005225  0.381
2009 Schuckit MA, Smith TL, Danko GP, Trim R, Bucholz KK, Edenberg HJ, Hesselbrock V, Kramer JJ, Dick DM. An evaluation of the full level of response to alcohol model of heavy drinking and problems in COGA offspring. Journal of Studies On Alcohol and Drugs. 70: 436-45. PMID 19371495 DOI: 10.15288/Jsad.2009.70.436  0.409
2009 McCutcheon VV, Heath AC, Edenberg HJ, Grucza RA, Hesselbrock VM, Kramer JR, Bierut LJ, Bucholz KK. Alcohol criteria endorsement and psychiatric and drug use disorders among DUI offenders: greater severity among women and multiple offenders. Addictive Behaviors. 34: 432-9. PMID 19167170 DOI: 10.1016/J.Addbeh.2008.12.003  0.42
2009 Sanford JR, Wang X, Mort M, Vanduyn N, Cooper DN, Mooney SD, Edenberg HJ, Liu Y. Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. Genome Research. 19: 381-94. PMID 19116412 DOI: 10.1101/Gr.082503.108  0.308
2009 Zhang D, Cheng L, Qian Y, Alliey-Rodriguez N, Kelsoe JR, Greenwood T, Nievergelt C, Barrett TB, McKinney R, Schork N, Smith EN, Bloss C, Nurnberger J, Edenberg HJ, Foroud T, et al. Singleton deletions throughout the genome increase risk of bipolar disorder. Molecular Psychiatry. 14: 376-80. PMID 19114987 DOI: 10.1038/Mp.2008.144  0.323
2009 Agrawal A, Wetherill L, Dick DM, Xuei X, Hinrichs A, Hesselbrock V, Kramer J, Nurnberger JI, Schuckit M, Bierut LJ, Edenberg HJ, Foroud T. Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150: 736-740. PMID 19016476 DOI: 10.1002/Ajmg.B.30881  0.366
2009 Chen AC, Tang Y, Rangaswamy M, Wang JC, Almasy L, Foroud T, Edenberg HJ, Hesselbrock V, Nurnberger J, Kuperman S, O'Connor SJ, Schuckit MA, Bauer LO, Tischfield J, Rice JP, et al. Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 359-68. PMID 18618593 DOI: 10.1002/Ajmg.B.30818  0.448
2009 Wang JC, Grucza R, Cruchaga C, Hinrichs AL, Bertelsen S, Budde JP, Fox L, Goldstein E, Reyes O, Saccone N, Saccone S, Xuei X, Bucholz K, Kuperman S, Nurnberger J, ... ... Edenberg HJ, et al. Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. Molecular Psychiatry. 14: 501-10. PMID 18414406 DOI: 10.1038/Mp.2008.42  0.46
2009 Le-Niculescu H, Kurian SM, Yehyawi N, Dike C, Patel SD, Edenberg HJ, Tsuang MT, Salomon DR, Nurnberger JI, Niculescu AB. Identifying blood biomarkers for mood disorders using convergent functional genomics. Molecular Psychiatry. 14: 156-74. PMID 18301394 DOI: 10.1038/Mp.2008.11  0.352
2008 Liu L, Foroud T, Xuei X, Berrettini W, Byerley W, Coryell W, El-Mallakh R, Gershon ES, Kelsoe JR, Lawson WB, MacKinnon DF, McInnis M, McMahon FJ, Murphy DL, Rice J, ... ... Edenberg HJ, et al. Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder. Psychiatric Genetics. 18: 267-74. PMID 19018231 DOI: 10.1097/Ypg.0B013E3283060F59  0.33
2008 Taylor MW, Tsukahara T, McClintick JN, Edenberg HJ, Kwo P. Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment Journal of Translational Medicine. 6. PMID 18986530 DOI: 10.1186/1479-5876-6-66  0.32
2008 Wetherill L, Schuckit MA, Hesselbrock V, Xuei X, Liang T, Dick DM, Kramer J, Nurnberger JI, Tischfield JA, Porjesz B, Edenberg HJ, Foroud T. Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence. Alcoholism, Clinical and Experimental Research. 32: 2031-40. PMID 18828811 DOI: 10.1111/J.1530-0277.2008.00790.X  0.436
2008 Kramer JR, Chan G, Dick DM, Kuperman S, Bucholz KK, Edenberg HJ, Polgreen LA, Hesselbrock VM, Schuckit MA, Nurnberger JI, Kapp ES, Porjesz B, Bierut LJ. Multiple-domain predictors of problematic alcohol use in young adulthood. Journal of Studies On Alcohol and Drugs. 69: 649-59. PMID 18781239 DOI: 10.15288/Jsad.2008.69.649  0.396
2008 Alam I, Sun Q, Liu L, Koller DL, Liu Y, Edenberg HJ, Econs MJ, Foroud T, Turner CH. Genomic expression analysis of rat chromosome 4 for skeletal traits at femoral neck. Physiological Genomics. 35: 191-6. PMID 18728226 DOI: 10.1152/Physiolgenomics.90237.2008  0.311
2008 Ross J, Berrettini W, Coryell W, Gershon ES, Badner JA, Kelsoe JR, McInnis MG, McMahon FJ, Murphy DL, Nurnberger JI, Foroud T, Rice JP, Scheftner WB, Zandi P, Edenberg H, et al. Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20. Psychiatric Genetics. 18: 191-8. PMID 18628681 DOI: 10.1097/Ypg.0B013E3283050Aa5  0.331
2008 Zhang H, Rider SD, Henderson JT, Fountain M, Chuang K, Kandachar V, Simons A, Edenberg HJ, Romero-Severson J, Muir WM, Ogas J. The CHD3 remodeler PICKLE promotes trimethylation of histone H3 lysine 27. The Journal of Biological Chemistry. 283: 22637-48. PMID 18539592 DOI: 10.1074/Jbc.M802129200  0.309
2008 Bierut LJ, Stitzel JA, Wang JC, Hinrichs AL, Grucza RA, Xuei X, Saccone NL, Saccone SF, Bertelsen S, Fox L, Horton WJ, Breslau N, Budde J, Cloninger CR, Dick DM, ... ... Edenberg HJ, et al. Variants in nicotinic receptors and risk for nicotine dependence. The American Journal of Psychiatry. 165: 1163-71. PMID 18519524 DOI: 10.1176/Appi.Ajp.2008.07111711  0.303
2008 Grucza RA, Wang JC, Stitzel JA, Hinrichs AL, Saccone SF, Saccone NL, Bucholz KK, Cloninger CR, Neuman RJ, Budde JP, Fox L, Bertelsen S, Kramer J, Hesselbrock V, Tischfield J, ... ... Edenberg HJ, et al. A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. Biological Psychiatry. 64: 922-9. PMID 18519132 DOI: 10.1016/J.Biopsych.2008.04.018  0.3
2008 Ichikawa S, Koller DL, Curry LR, Lai D, Xuei X, Pugh EW, Tsai YY, Doheny KF, Edenberg HJ, Hui SL, Foroud T, Peacock M, Econs MJ. Identification of a linkage disequilibrium block in chromosome 1q associated with BMD in premenopausal white women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 1680-8. PMID 18505370 DOI: 10.1359/Jbmr.080509  0.314
2008 Schuckit MA, Danko GP, Smith TL, Bierut LJ, Bucholz KK, Edenberg HJ, Hesselbrock V, Kramer J, Nurnberger JI, Trim R, Allen R, Kreikebaum S, Hinga B. The prognostic implications of DSM-IV abuse criteria in drinking adolescents. Drug and Alcohol Dependence. 97: 94-104. PMID 18479842 DOI: 10.1016/J.Drugalcdep.2008.03.020  0.387
2008 Ghosh S, Bierut LJ, Porjesz B, Edenberg HJ, Dick D, Goate A, Hesselbrock V, Nurnberger J, Foroud T, Kramer J, Rice J, Begleiter H. A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 147: 1301-1305. PMID 18454434 DOI: 10.1002/Ajmg.B.30735  0.425
2008 Foroud T, Wetherill LF, Kramer J, Tischfield JA, Nurnberger JI, Schuckit MA, Xuei X, Edenberg HJ. The tachykinin receptor 3 is associated with alcohol and cocaine dependence. Alcoholism, Clinical and Experimental Research. 32: 1023-30. PMID 18422838 DOI: 10.1111/J.1530-0277.2008.00663.X  0.436
2008 Rodd ZA, Kimpel MW, Edenberg HJ, Bell RL, Strother WN, McClintick JN, Carr LG, Liang T, McBride WJ. Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. Pharmacology, Biochemistry, and Behavior. 89: 481-98. PMID 18405950 DOI: 10.1016/J.Pbb.2008.01.023  0.317
2008 Wang G, Wang X, Wang Y, Yang JY, Li L, Nephew KP, Edenberg HJ, Zhou FC, Liu Y. Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome. Bmc Genomics. 9: S19. PMID 18366608 DOI: 10.1186/1471-2164-9-S1-S19  0.392
2008 Edenberg HJ, Wang J, Tian H, Pochareddy S, Xuei X, Wetherill L, Goate A, Hinrichs T, Kuperman S, Nurnberger JI, Schuckit M, Tischfield JA, Foroud T. A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence. Human Molecular Genetics. 17: 1783-9. PMID 18319328 DOI: 10.1093/Hmg/Ddn068  0.451
2008 Dick DM, Aliev F, Wang JC, Grucza RA, Schuckit M, Kuperman S, Kramer J, Hinrichs A, Bertelsen S, Budde JP, Hesselbrock V, Porjesz B, Edenberg HJ, Bierut LJ, Goate A. Using dimensional models of externalizing psychopathology to aid in gene identification. Archives of General Psychiatry. 65: 310-8. PMID 18316677 DOI: 10.1001/Archpsyc.65.3.310  0.384
2008 Schuckit MA, Smith TL, Hesselbrock V, Bucholz KK, Bierut L, Edenberg H, Kramer J, Longacre E, Fukukura T, Kalmijn J, Danko GP, Trim R. Clinical implications of tolerance to alcohol in nondependent young drinkers. The American Journal of Drug and Alcohol Abuse. 34: 133-49. PMID 18293230 DOI: 10.1080/00952990701877003  0.411
2008 Le-Niculescu H, McFarland MJ, Ogden CA, Balaraman Y, Patel S, Tan J, Rodd ZA, Paulus M, Geyer MA, Edenberg HJ, Glatt SJ, Faraone SV, Nurnberger JI, Kuczenski R, Tsuang MT, et al. Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 134-66. PMID 18247375 DOI: 10.1002/Ajmg.B.30707  0.426
2008 Dick DM, Aliev F, Wang JC, Saccone S, Hinrichs A, Bertelsen S, Budde J, Saccone N, Foroud T, Nurnberger J, Xuei X, Conneally PM, Schuckit M, Almasy L, Crowe R, ... ... Edenberg HJ, et al. A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9. Biological Psychiatry. 63: 1047-53. PMID 18163977 DOI: 10.1016/J.Biopsych.2007.11.005  0.463
2008 Edenberg HJ, Xuei X, Wetherill LF, Bierut L, Bucholz K, Dick DM, Hesselbrock V, Kuperman S, Porjesz B, Schuckit MA, Tischfield JA, Almasy LA, Nurnberger JI, Foroud T. Association of NFKB1, which encodes a subunit of the transcription factor NF-kappaB, with alcohol dependence. Human Molecular Genetics. 17: 963-70. PMID 18079108 DOI: 10.1093/Hmg/Ddm368  0.473
2008 Labbe A, McClintick J, Martinez M, Beyenne J, Chen L, de Andrade M, Edenberg HJ, Kim Y, Liu KY, Liu Y, Ma J, Peng B, Peng J, Peralta JM, Qin S, et al. Summary of contributions to GAW15 Group 16: processing/normalization of expression traits. Genetic Epidemiology. S132-8. PMID 18046755 DOI: 10.1002/Gepi.20290  0.748
2008 Agrawal A, Hinrichs AL, Dunn G, Bertelsen S, Dick DM, Saccone SF, Saccone NL, Grucza RA, Wang JC, Cloninger CR, Edenberg HJ, Foroud T, Hesselbrock V, Kramer J, Bucholz KK, et al. Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Drug and Alcohol Dependence. 93: 12-20. PMID 17942244 DOI: 10.1016/J.Drugalcdep.2007.08.015  0.411
2008 Travers JB, Edenberg HJ, Zhang Q, Al-Hassani M, Yi Q, Baskaran S, Konger RL. Augmentation of UVB radiation-mediated early gene expression by the epidermal platelet-activating factor receptor. The Journal of Investigative Dermatology. 128: 455-60. PMID 17928889 DOI: 10.1038/Sj.Jid.5701083  0.303
2008 Xuei X, Flury-Wetherill L, Almasy L, Bierut L, Tischfield J, Schuckit M, Nurnberger JI, Foroud T, Edenberg HJ. Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence. Addiction Biology. 13: 80-7. PMID 17910740 DOI: 10.1111/J.1369-1600.2007.00082.X  0.433
2008 Foroud T, Ichikawa S, Koller D, Lai D, Curry L, Xuei X, Edenberg HJ, Hui S, Peacock M, Econs MJ. Association studies of ALOX5 and bone mineral density in healthy adults Osteoporosis International. 19: 637-643. PMID 17909879 DOI: 10.1007/S00198-007-0484-Z  0.313
2007 McClintick JN, Liu Y, Edenberg HJ. Mapping of trans-acting regulatory factors from microarray data. Bmc Proceedings. S155. PMID 18466500 DOI: 10.1186/1753-6561-1-S1-S155  0.33
2007 Humphreys TL, Li L, Li X, Janowicz DM, Fortney KR, Zhao Q, Li W, McClintick J, Katz BP, Wilkes DS, Edenberg HJ, Spinola SM. Dysregulated immune profiles for skin and dendritic cells are associated with increased host susceptibility to Haemophilus ducreyi infection in human volunteers. Infection and Immunity. 75: 5686-97. PMID 17893130 DOI: 10.1128/Iai.00777-07  0.722
2007 Dick DM, Wang JC, Plunkett J, Aliev F, Hinrichs A, Bertelsen S, Budde JP, Goldstein EL, Kaplan D, Edenberg HJ, Nurnberger J, Hesselbrock V, Schuckit M, Kuperman S, Tischfield J, et al. Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1. Alcoholism, Clinical and Experimental Research. 31: 1645-53. PMID 17850642 DOI: 10.1111/J.1530-0277.2007.00470.X  0.465
2007 Foroud T, Wetherill LF, Dick DM, Hesselbrock V, Nurnberger JI, Kramer J, Tischfield J, Schuckit M, Bierut LJ, Xuei X, Edenberg HJ. Lack of association of alcohol dependence and habitual smoking with catechol-O-methyltransferase. Alcoholism, Clinical and Experimental Research. 31: 1773-9. PMID 17850222 DOI: 10.1111/J.1530-0277.2007.00505.X  0.359
2007 Edenberg HJ. The genetics of alcohol metabolism: Role of alcohol dehydrogenase and aldehyde dehydrogenase variants Alcohol Research and Health. 30: 5-13. PMID 17718394  0.338
2007 Dick DM, Agrawal A, Wang JC, Hinrichs A, Bertelsen S, Bucholz KK, Schuckit M, Kramer J, Nurnberger J, Tischfield J, Edenberg HJ, Goate A, Bierut LJ. Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk. Addiction (Abingdon, England). 102: 1131-9. PMID 17567401 DOI: 10.1111/J.1360-0443.2007.01871.X  0.438
2007 Kimpel MW, Strother WN, McClintick JN, Carr LG, Liang T, Edenberg HJ, McBride WJ. Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. Alcohol (Fayetteville, N.Y.). 41: 95-132. PMID 17517326 DOI: 10.1016/J.Alcohol.2007.03.003  0.425
2007 Xuei X, Flury-Wetherill L, Bierut L, Dick D, Nurnberger J, Foroud T, Edenberg HJ. The opioid system in alcohol and drug dependence: Family-based association study American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 144: 877-884. PMID 17503481 DOI: 10.1002/Ajmg.B.30531  0.398
2007 Carr LG, Kimpel MW, Liang T, McClintick JN, McCall K, Morse M, Edenberg HJ. Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. Alcoholism, Clinical and Experimental Research. 31: 1089-98. PMID 17451403 DOI: 10.1111/J.1530-0277.2007.00397.X  0.406
2007 Foroud T, Wetherill LF, Liang T, Dick DM, Hesselbrock V, Kramer J, Nurnberger J, Schuckit M, Carr L, Porjesz B, Xuei X, Edenberg HJ. Association of alcohol craving with alpha-synuclein (SNCA). Alcoholism, Clinical and Experimental Research. 31: 537-45. PMID 17374032 DOI: 10.1111/J.1530-0277.2007.00337.X  0.423
2007 Le-Niculescu H, Balaraman Y, Patel S, Tan J, Sidhu K, Jerome RE, Edenberg HJ, Kuczenski R, Geyer MA, Nurnberger JI, Faraone SV, Tsuang MT, Niculescu AB. Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 129-58. PMID 17266109 DOI: 10.1002/Ajmg.B.30481  0.345
2007 Wang JC, Hinrichs AL, Bertelsen S, Stock H, Budde JP, Dick DM, Bucholz KK, Rice J, Saccone N, Edenberg HJ, Hesselbrock V, Kuperman S, Schuckit MA, Bierut LJ, Goate AM. Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. Alcoholism, Clinical and Experimental Research. 31: 209-15. PMID 17250611 DOI: 10.1111/J.1530-0277.2006.00297.X  0.448
2007 Dick DM, Plunkett J, Hamlin D, Nurnberger J, Kuperman S, Schuckit M, Hesselbrock V, Edenberg H, Bierut L. Association analyses of the serotonin transporter gene with lifetime depression and alcohol dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Psychiatric Genetics. 17: 35-8. PMID 17167343 DOI: 10.1097/Ypg.0B013E328011188B  0.413
2007 Dick DM, Aliev F, Kramer J, Wang JC, Hinrichs A, Bertelsen S, Kuperman S, Schuckit M, Nurnberger J, Edenberg HJ, Porjesz B, Begleiter H, Hesselbrock V, Goate A, Bierut L. Association of CHRM2 with IQ: converging evidence for a gene influencing intelligence. Behavior Genetics. 37: 265-72. PMID 17160701 DOI: 10.1007/S10519-006-9131-2  0.391
2007 Rodd ZA, Bertsch BA, Strother WN, Le-Niculescu H, Balaraman Y, Hayden E, Jerome RE, Lumeng L, Nurnberger JI, Edenberg HJ, McBride WJ, Niculescu AB. Candidate genes, pathways and mechanisms for alcoholism: an expanded convergent functional genomics approach. The Pharmacogenomics Journal. 7: 222-56. PMID 17033615 DOI: 10.1038/Sj.Tpj.6500420  0.454
2006 Edenberg HJ, Foroud T. The genetics of alcoholism: Identifying specific genes through family studies Addiction Biology. 11: 386-396. PMID 16961766 DOI: 10.1111/J.1369-1600.2006.00035.X  0.494
2006 Xuei X, Dick D, Flury-Wetherill L, Tian HJ, Agrawal A, Bierut L, Goate A, Bucholz K, Schuckit M, Nurnberger J, Tischfield J, Kuperman S, Porjesz B, Begleiter H, Foroud T, ... Edenberg HJ, et al. Association of the kappa-opioid system with alcohol dependence. Molecular Psychiatry. 11: 1016-24. PMID 16924269 DOI: 10.1038/Sj.Mp.4001882  0.373
2006 Johnson C, Drgon T, Liu QR, Walther D, Edenberg H, Rice J, Foroud T, Uhl GR. Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 844-53. PMID 16894614 DOI: 10.1002/Ajmg.B.30346  0.474
2006 Dannenberg LO, Edenberg HJ. Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation. Bmc Genomics. 7: 181. PMID 16854234 DOI: 10.1186/1471-2164-7-181  0.775
2006 Jones KA, Porjesz B, Almasy L, Bierut L, Dick D, Goate A, Hinrichs A, Rice JP, Wang JC, Bauer LO, Crowe R, Foroud T, Hesselbrock V, Kuperman S, Nurnberger J, ... ... Edenberg HJ, et al. A cholinergic receptor gene (CHRM2) affects event-related oscillations. Behavior Genetics. 36: 627-39. PMID 16823639 DOI: 10.1007/S10519-006-9075-6  0.303
2006 Dick DM, Plunkett J, Wetherill LF, Xuei X, Goate A, Hesselbrock V, Schuckit M, Crowe R, Edenberg HJ, Foroud T. Association between GABRA1 and drinking behaviors in the Collaborative Study on the Genetics of Alcoholism sample Alcoholism: Clinical and Experimental Research. 30: 1101-1110. PMID 16792556 DOI: 10.1111/J.1530-0277.2006.00136.X  0.454
2006 Dannenberg LO, Chen HJ, Tian H, Edenberg HJ. Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. Alcoholism, Clinical and Experimental Research. 30: 928-37. PMID 16737450 DOI: 10.1111/J.1530-0277.2006.00107.X  0.777
2006 Liu Y, Taylor MW, Edenberg HJ. Model-based identification of cis-acting elements from microarray data Genomics. 88: 452-461. PMID 16716564 DOI: 10.1016/J.Ygeno.2006.04.006  0.329
2006 Agrawal A, Edenberg HJ, Foroud T, Bierut LJ, Dunne G, Hinrichs AL, Nurnberger JI, Crowe R, Kuperman S, Schuckit MA, Begleiter H, Porjesz B, Dick DM. Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample. Behavior Genetics. 36: 640-50. PMID 16622805 DOI: 10.1007/S10519-006-9069-4  0.429
2006 Edenberg HJ, Xuei X, Chen HJ, Tian H, Wetherill LF, Dick DM, Almasy L, Bierut L, Bucholz KK, Goate A, Hesselbrock V, Kuperman S, Nurnberger J, Porjesz B, Rice J, et al. Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Human Molecular Genetics. 15: 1539-49. PMID 16571603 DOI: 10.1093/Hmg/Ddl073  0.472
2006 Dick DM, Agrawal A, Schuckit MA, Bierut L, Hinrichs A, Fox L, Mullaney J, Cloninger CR, Hesselbrock V, Nurnberger JI, Almasy L, Foroud T, Porjesz B, Edenberg H, Begleiter H. Marital status, alcohol dependence, and GABRA2: evidence for gene-environment correlation and interaction. Journal of Studies On Alcohol. 67: 185-94. PMID 16562401 DOI: 10.15288/Jsa.2006.67.185  0.441
2006 Dick DM, Bierut L, Hinrichs A, Fox L, Bucholz KK, Kramer J, Kuperman S, Hesselbrock V, Schuckit M, Almasy L, Tischfield J, Porjesz B, Begleiter H, Nurnberger J, Xuei X, ... Edenberg HJ, et al. The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages. Behavior Genetics. 36: 577-90. PMID 16557364 DOI: 10.1007/S10519-005-9041-8  0.399
2006 Hinrichs AL, Wang JC, Bufe B, Kwon JM, Budde J, Allen R, Bertelsen S, Evans W, Dick D, Rice J, Foroud T, Nurnberger J, Tischfield JA, Kuperman S, Crowe R, ... ... Edenberg HJ, et al. Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. American Journal of Human Genetics. 78: 103-11. PMID 16385453 DOI: 10.1086/499253  0.426
2006 Dick DM, Jones K, Saccone N, Hinrichs A, Wang JC, Goate A, Bierut L, Almasy L, Schuckit M, Hesselbrock V, Tischfield J, Foroud T, Edenberg H, Porjesz B, Begleiter H. Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. Behavior Genetics. 36: 112-26. PMID 16341909 DOI: 10.1007/S10519-005-9001-3  0.442
2006 McClintick JN, Crabb DW, Tian H, Pinaire J, Smith JR, Jerome RE, Edenberg HJ. Global effects of vitamin A deficiency on gene expression in rat liver: evidence for hypoandrogenism Journal of Nutritional Biochemistry. 17: 345-355. PMID 16214324 DOI: 10.1016/J.Jnutbio.2005.08.006  0.303
2005 Bergeson SE, Berman AE, Dodd PR, Edenberg HJ, Hitzemann RJ, Lewohl JM, Lodowski KH, Sommer WH. Expression Profiling in Alcoholism Research. Alcoholism, Clinical and Experimental Research. 29: 1066-1073. PMID 21512613 DOI: 10.1097/01.Alc.0000171043.29384.3E  0.432
2005 Edenberg HJ, Bierut LJ, Boyce P, Cao M, Cawley S, Chiles R, Doheny KF, Hansen M, Hinrichs T, Jones K, Kelleher M, Kennedy GC, Liu G, Marcus G, McBride C, et al. Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14. Bmc Genetics. 6: S2. PMID 16451628 DOI: 10.1186/1471-2156-6-S1-S2  0.456
2005 McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, ... ... Edenberg HJ, et al. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. American Journal of Human Genetics. 77: 582-95. PMID 16175504 DOI: 10.1086/491603  0.335
2005 Dannenberg LO, Chen HJ, Edenberg HJ. GATA-2 and HNF-3beta regulate the human alcohol dehydrogenase 1A (ADH1A) gene. Dna and Cell Biology. 24: 543-52. PMID 16153155 DOI: 10.1089/Dna.2005.24.543  0.772
2005 Edenberg HJ, Kranzler HR. The contribution of genetics to addiction therapy approaches Pharmacology and Therapeutics. 108: 86-93. PMID 16026844 DOI: 10.1016/J.Pharmthera.2005.06.011  0.399
2005 Tian H, Chen HJ, Cross TH, Edenberg HJ. Alternative splicing and promoter use in the human GABRA2 gene. Brain Research. Molecular Brain Research. 137: 174-83. PMID 15950776 DOI: 10.1016/J.Molbrainres.2005.03.001  0.402
2005 Corbett J, Saccone NL, Foroud T, Goate A, Edenberg H, Nurnberger J, Porjesz B, Begleiter H, Reich T, Rice JP. A sex-adjusted and age-adjusted genome screen for nested alcohol dependence diagnoses. Psychiatric Genetics. 15: 25-30. PMID 15722954 DOI: 10.1097/00041444-200503000-00005  0.444
2005 McBride WJ, Kerns RT, Rodd ZA, Strother WN, Edenberg HJ, Hashimoto JG, Wiren KM, Miles MF. Alcohol effects on central nervous system gene expression in genetic animal models. Alcoholism, Clinical and Experimental Research. 29: 167-75. PMID 15714040 DOI: 10.1097/01.Alc.0000153539.40955.42  0.412
2005 Dick DM, Edenberg HJ, Xuei X, Goate A, Hesselbrock V, Schuckit M, Crowe R, Foroud T. No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample American Journal of Medical Genetics - Neuropsychiatric Genetics. 132: 24-28. PMID 15690551 DOI: 10.1002/Ajmg.B.30058  0.461
2005 Edenberg HJ, Strother WN, McClintick JN, Tian H, Stephens M, Jerome RE, Lumeng L, Li TK, McBride WJ. Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. Genes, Brain, and Behavior. 4: 20-30. PMID 15660665 DOI: 10.1111/J.1601-183X.2004.00091.X  0.418
2005 Chen HJ, Tian H, Edenberg HJ. Natural haplotypes in the regulatory sequences affect human alcohol dehydrogenase 1C (ADH1C) gene expression. Human Mutation. 25: 150-5. PMID 15643610 DOI: 10.1002/Humu.20127  0.466
2005 Koller DL, Ichikawa S, Johnson ML, Lai D, Xuei X, Edenberg HJ, Conneally PM, Hui SL, Johnston CC, Peacock M, Foroud T, Econs MJ. Contribution of the LRP5 gene to normal variation in peak BMD in women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 75-80. PMID 15619672 DOI: 10.1359/Jbmr.041019  0.337
2005 Li Y, McClintick J, Zhong L, Edenberg HJ, Yoder MC, Chan RJ. Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood. 105: 635-7. PMID 15358627 DOI: 10.1182/Blood-2004-07-2681  0.731
2005 Bailey-Wilson JE, Almasy L, Edenberg H, Greenberg DA, Hansen MS, Kennedy GC, Thomas D, W. Pugh E, MacCluer JW. Genetic Analysis Workshop 14: Introduction to Workshop Summaries Genetic Epidemiology. 29: S1-S6. DOI: 10.1002/Gepi.20105  0.357
2004 Wang JC, Hinrichs AL, Stock H, Budde J, Allen R, Bertelsen S, Kwon JM, Wu W, Dick DM, Rice J, Jones K, Nurnberger JI, Tischfield J, Porjesz B, Edenberg HJ, et al. Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. Human Molecular Genetics. 13: 1903-11. PMID 15229186 DOI: 10.1093/Hmg/Ddh194  0.443
2004 Hesselbrock V, Dick D, Hesselbrock M, Foroud T, Schuckit M, Edenberg H, Bucholz K, Kramer J, Reich T, Goate A, Bierut L, Rice JP, Nurnberger JI. The search for genetic risk factors associated with suicidal behavior. Alcoholism, Clinical and Experimental Research. 28: 70S-76S. PMID 15166638 DOI: 10.1097/01.Alc.0000127416.92128.B0  0.362
2004 Edenberg HJ, Dick DM, Xuei X, Tian H, Almasy L, Bauer LO, Crowe RR, Goate A, Hesselbrock V, Jones K, Kwon J, Li TK, Nurnberger JI, O'Connor SJ, Reich T, et al. Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. American Journal of Human Genetics. 74: 705-14. PMID 15024690 DOI: 10.1086/383283  0.46
2004 Taylor MW, Grosse WM, Schaley JE, Sanda C, Wu X, Chien SC, Smith F, Wu TG, Stephens M, Ferris MW, McClintick JN, Jerome RE, Edenberg HJ. Global effect of PEG-IFN-alpha and ribavirin on gene expression in PBMC in vitro. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 24: 107-18. PMID 14980075 DOI: 10.1089/107999004322813354  0.308
2004 Dick DM, Edenberg HJ, Xuei X, Goate A, Kuperman S, Schuckit M, Crowe R, Smith TL, Porjesz B, Begleiter H, Foroud T. Association of GABRG3 with alcohol dependence. Alcoholism, Clinical and Experimental Research. 28: 4-9. PMID 14745296 DOI: 10.1097/01.Alc.0000108645.54345.98  0.428
2004 Dick DM, Li TK, Edenberg HJ, Hesselbrock V, Kramer J, Kuperman S, Porjesz B, Bucholz K, Goate A, Nurnberger J, Foroud T. A genome-wide screen for genes influencing conduct disorder. Molecular Psychiatry. 9: 81-6. PMID 14699444 DOI: 10.1038/Sj.Mp.4001368  0.444
2004 Bierut LJ, Rice JP, Goate A, Hinrichs AL, Saccone NL, Foroud T, Edenberg HJ, Cloninger CR, Begleiter H, Conneally PM, Crowe RR, Hesselbrock V, Li TK, Nurnberger JI, Porjesz B, et al. A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. American Journal of Medical Genetics. Part A. 124: 19-27. PMID 14679582 DOI: 10.1002/Ajmg.A.20329  0.388
2004 Edenberg HJ. GENE EXPRESSION IN BRAINS OF ALCOHOL-PREFERRING AND NON-PREFERRING RATS. Alcoholism: Clinical & Experimental Research. 28: 53A. DOI: 10.1097/00000374-200408002-00281  0.385
2003 McInnis MG, Dick DM, Willour VL, Avramopoulos D, MacKinnon DF, Simpson SG, Potash JB, Edenberg HJ, Bowman ES, McMahon FJ, Smiley C, Chellis JL, Huo Y, Diggs T, Meyer ET, et al. Genome-wide scan and conditional analysis in bipolar disorder: evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees. Biological Psychiatry. 54: 1265-73. PMID 14643094 DOI: 10.1016/J.Biopsych.2003.08.001  0.336
2003 Dean Rider S, Henderson JT, Jerome RE, Edenberg HJ, Romero-Severson J, Ogas J. Coordinate repression of regulators of embryonic identity by PICKLE during germination in Arabidopsis. The Plant Journal : For Cell and Molecular Biology. 35: 33-43. PMID 12834400 DOI: 10.1046/J.1365-313X.2003.01783.X  0.349
2003 Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI, Craddock N, DePaulo JR, Baron M, Gershon ES, Ekholm J, Cichon S, Turecki G, Claes S, Kelsoe JR, ... ... Edenberg HJ, et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. American Journal of Human Genetics. 73: 49-62. PMID 12802785 DOI: 10.1086/376547  0.306
2003 Fleet JC, Wang L, Vitek O, Craig BA, Edenberg HJ. Gene expression profiling of Caco-2 BBe cells suggests a role for specific signaling pathways during intestinal differentiation. Physiological Genomics. 13: 57-68. PMID 12644633 DOI: 10.1152/Physiolgenomics.00152.2002  0.341
2003 Ghosh S, Begleiter H, Porjesz B, Chorlian DB, Edenberg HJ, Foroud T, Goate A, Reich T. Linkage mapping of Beta 2 EEG waves via non-parametric regression American Journal of Medical Genetics - Neuropsychiatric Genetics. 118: 66-71. PMID 12627469 DOI: 10.1002/Ajmg.B.10057  0.336
2003 Hoffman PL, Miles M, Edenberg HJ, Sommer W, Tabakoff B, Wehner JM, Lewohl J. Gene expression in brain: a window on ethanol dependence, neuroadaptation, and preference. Alcoholism, Clinical and Experimental Research. 27: 155-68. PMID 12605065 DOI: 10.1097/01.Alc.0000060101.89334.11  0.349
2003 Song J, Koller DL, Foroud T, Carr K, Zhao J, Rice J, Nurnberger JI, Begleiter H, Porjesz B, Smith TL, Schuckit MA, Edenberg HJ. Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 117: 39-45. PMID 12555233 DOI: 10.1002/Ajmg.B.10022  0.449
2003 Breese MR, Stephens MJ, McClintick JN, Grow MW, Edenberg HJ. Labrat LIMS: An extensible framework for developing laboratory information management, analysis, and bioinformatics solutions for microarrays Proceedings of the Acm Symposium On Applied Computing. 103-108.  0.699
2002 Bierut LJ, Saccone NL, Rice JP, Goate A, Foroud T, Edenberg H, Almasy L, Conneally PM, Crowe R, Hesselbrock V, Li TK, Nurnberger J, Porjesz B, Schuckit MA, Tischfield J, et al. Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 26: 208-13. PMID 12875049  0.327
2002 Osier MV, Pakstis AJ, Goldman D, Edenberg HJ, Kidd JR, Kidd KK. A proline-threonine substitution in codon 351 of ADH1C is common in Native Americans. Alcoholism, Clinical and Experimental Research. 26: 1759-63. PMID 12500098 DOI: 10.1111/J.1530-0277.2002.Tb02481.X  0.397
2002 Chen HJ, Carr K, Jerome RE, Edenberg HJ. A retroviral repetitive element confers tissue-specificity to the human alcohol dehydrogenase 1C (ADH1C) gene. Dna and Cell Biology. 21: 793-801. PMID 12489990 DOI: 10.1089/104454902320908441  0.352
2002 Dick DM, Nurnberger J, Edenberg HJ, Goate A, Crowe R, Rice J, Bucholz KK, Kramer J, Schuckit MA, Smith TL, Porjesz B, Begleiter H, Hesselbrock V, Foroud T. Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype. Alcoholism, Clinical and Experimental Research. 26: 1453-60. PMID 12394277 DOI: 10.1111/J.1530-0277.2002.Tb02443.X  0.459
2002 Porjesz B, Begleiter H, Wang K, Almasy L, Chorlian DB, Stimus AT, Kuperman S, O'Connor SJ, Rohrbaugh J, Bauer LO, Edenberg HJ, Goate A, Rice JP, Reich T. Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biological Psychology. 61: 229-48. PMID 12385677 DOI: 10.1016/S0301-0511(02)00060-1  0.427
2002 Carr LG, Foroud T, Stewart T, Castelluccio P, Edenberg HJ, Li TK. Influence of ADH1B polymorphism on alcohol use and its subjective effects in a Jewish population American Journal of Medical Genetics. 112: 138-143. PMID 12244546 DOI: 10.1002/Ajmg.10674  0.399
2002 Dick DM, Foroud T, Edenberg HJ, Miller M, Bowman E, Rau NL, DePaulo JR, McInnis M, Gershon E, McMahon F, Rice JP, Bierut LJ, Reich T, Nurnberger J. Apparent replication of suggestive linkage on chromosome 16 in the NIMH genetics initiative bipolar pedigrees. American Journal of Medical Genetics. 114: 407-12. PMID 11992562 DOI: 10.1002/Ajmg.10380  0.318
2001 Nurnberger JI, Foroud T, Flury L, Su J, Meyer ET, Hu K, Crowe R, Edenberg H, Goate A, Bierut L, Reich T, Schuckit M, Reich W. Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder American Journal of Psychiatry. 158: 718-724. PMID 11329392 DOI: 10.1176/Appi.Ajp.158.5.718  0.383
2001 Schuckit MA, Edenberg HJ, Kalmijn J, Flury L, Smith TL, Reich T, Bierut L, Goate A, Foroud T. A genome-wide search for genes that relate to a low level of response to alcohol. Alcoholism, Clinical and Experimental Research. 25: 323-9. PMID 11290841 DOI: 10.1111/J.1530-0277.2001.Tb02217.X  0.452
2001 Almasy L, Porjesz B, Blangero J, Goate A, Edenberg HJ, Chorlian DB, Kuperman S, O'Connor SJ, Rohrbaugh J, Bauer LO, Foroud T, Rice JP, Reich T, Begleiter H. Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism. American Journal of Human Genetics. 68: 128-135. PMID 11102287 DOI: 10.1086/316936  0.343
2000 McClintick J, Edenberg HJ. Blastreport: A PERL script to facilitate the use of sequence databases for mapping and clustering Biotechniques. 29: 1272-1276. PMID 11126131 DOI: 10.2144/00296Bc03  0.726
2000 Saccone NL, Kwon JM, Corbett J, Goate A, Rochberg N, Edenberg HJ, Foroud T, Li TK, Begleiter H, Reich T, Rice JP. A genome screen of maximum number of drinks as an alcoholism phenotype American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 632-637. PMID 11054770 DOI: 10.1002/1096-8628(20001009)96:5<632::Aid-Ajmg8>3.0.Co;2-#  0.407
2000 Zhi X, Chan EM, Edenberg HJ. Tissue-specific regulatory elements in the human alcohol dehydrogenase 6 gene. Dna and Cell Biology. 19: 487-97. PMID 10975466 DOI: 10.1089/10445490050128412  0.349
2000 Bierut LJ, Rice JP, Edenberg HJ, Goate A, Foroud T, Cloninger CR, Begleiter H, Conneally PM, Crowe RR, Hesselbrock V, Li TK, Nurnberger JI, Porjesz B, Schuckit MA, Reich T. Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking. American Journal of Medical Genetics. 90: 299-302. PMID 10710227 DOI: 10.1002/(Sici)1096-8628(20000214)90:4<299::Aid-Ajmg7>3.0.Co;2-Y  0.344
2000 Edenberg HJ. Regulation of the mammalian alcohol dehydrogenase genes Progress in Nucleic Acid Research and Molecular Biology. 64: 295-341. PMID 10697413 DOI: 10.1016/S0079-6603(00)64008-4  0.44
2000 Foroud T, Castelluccio PF, Koller DL, Edenberg HJ, Miller M, Bowman E, Rau NL, Smiley C, Rice JP, Goate A, Armstrong C, Bierut LJ, Reich T, Detera-Wadleigh SD, Goldin LR, et al. Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees. American Journal of Medical Genetics. 96: 18-23. PMID 10686547 DOI: 10.1002/(Sici)1096-8628(20000207)96:1<18::Aid-Ajmg6>3.0.Co;2-G  0.31
2000 Foroud T, Edenberg HJ, Goate A, Rice J, Flury L, Koller DL, Bierut LJ, Conneally PM, Nurnberger JI, Bucholz KK, Li T, Hesselbrock V, Crowe R, Schuckit M, Porjesz B, et al. Alcoholism Susceptibility Loci: Confirmation Studies in a Replicate Sample and Further Mapping Alcoholism: Clinical and Experimental Research. 24: 933-945. DOI: 10.1111/J.1530-0277.2000.Tb04634.X  0.406
1999 Begleiter H, Reich T, Nurnberger J, Li TK, Conneally PM, Edenberg H, Crowe R, Kuperman S, Schuckit M, Bloom F, Hesselbrock V, Porjesz B, Cloninger CR, Rice J, Goate A. Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism. Genetic Epidemiology. 17: S25-30. PMID 10597407 DOI: 10.1002/Gepi.1370170705  0.433
1999 Saccone NL, Rice JP, Rochberg N, Goate A, Reich T, Shears S, Wu W, Nurnberger JI, Foroud T, Edenberg HJ, Li TK. Genome screen for platelet monoamine oxidase (MAO) activity. American Journal of Medical Genetics. 88: 517-21. PMID 10490709 DOI: 10.1002/(Sici)1096-8628(19991015)88:5<517::Aid-Ajmg15>3.0.Co;2-B  0.327
1999 Williams JT, Begleiter H, Porjesz B, Edenberg HJ, Foroud T, Reich T, Goate A, Van Eerdewegh P, Almasy L, Blangero J. Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials. American Journal of Human Genetics. 65: 1148-60. PMID 10486334 DOI: 10.1086/302571  0.432
1999 Edenberg HJ, Jerome RE, Li M. Polymorphism of the human alcohol dehydrogenase 4 (ADH4) promoter affects gene expression Pharmacogenetics. 9: 25-30. PMID 10208639 DOI: 10.1097/00008571-199902000-00004  0.445
1999 Osier M, Pakstis AJ, Kidd JR, Lee JF, Yin SJ, Ko HC, Edenberg HJ, Lu RB, Kidd KK. Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism. American Journal of Human Genetics. 64: 1147-57. PMID 10090900 DOI: 10.1086/302317  0.443
1998 Edenberg HJ. Genetics of alcoholism [6] Science. 282: 1269. PMID 9867631 DOI: 10.1126/Science.282.5392.1265I  0.479
1998 Goate AM, Edenberg HJ. The genetics of alcoholism. Current Opinion in Genetics & Development. 8: 282-6. PMID 9691005 DOI: 10.1016/S0959-437X(98)80082-8  0.458
1998 Cloninger CR, Van Eerdewegh P, Goate A, Edenberg HJ, Blangero J, Hesselbrock V, Reich T, Nurnberger J, Schuckit M, Porjesz B, Crowe R, Rice JP, Foroud T, Przybeck TR, Almasy L, et al. Anxiety proneness linked to epistatic loci in genome scan of human personality traits. American Journal of Medical Genetics. 81: 313-7. PMID 9674977 DOI: 10.1002/(Sici)1096-8628(19980710)81:4<313::Aid-Ajmg7>3.0.Co;2-U  0.338
1998 Begleiter H, Porjesz B, Reich T, Edenberg HJ, Goate A, Blangero J, Almasy L, Foroud T, Van Eerdewegh P, Polich J, Rohrbaugh J, Kuperman S, Bauer LO, O'Connor SJ, Chorlian DB, et al. Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalography and Clinical Neurophysiology. 108: 244-50. PMID 9607513 DOI: 10.1016/S0168-5597(98)00002-1  0.337
1998 Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eerdewegh P, Foroud T, Hesselbrock V, Schuckit MA, Bucholz K, Porjesz B, Li TK, Conneally PM, Nurnberger JI, Tischfield JA, et al. Genome-wide search for genes affecting the risk for alcohol dependence. American Journal of Medical Genetics. 81: 207-15. PMID 9603606 DOI: 10.1002/(Sici)1096-8628(19980508)81:3<207::Aid-Ajmg1>3.0.Co;2-T  0.457
1998 Li M, Edenberg HJ. Function of cis-acting elements in human alcohol dehydrogenase 4 (ADH4) promoter and role of C/EBP proteins in gene expression. Dna and Cell Biology. 17: 387-97. PMID 9570155 DOI: 10.1089/Dna.1998.17.387  0.331
1998 Porjesz B, Begleiter H, Reich T, Eerdewegh P, Edenberg HJ, Foroud T, Goate A, Litke A, Chorlian DB, Stirnus A, Rice J, Blangero J, Almasy L, Sorbell J, Bauer LO, et al. Amplitude of Visual P3 Event-Related Potential as a Phenotypic Marker for a Predisposition to Alcoholism: Preliminary Results from the COGA Project Alcoholism: Clinical and Experimental Research. 22: 1317-1323. DOI: 10.1111/J.1530-0277.1998.Tb03914.X  0.342
1998 Carr LG, Foroud T, Bice P, Gobbett T, Ivashina J, Edenberg H, Lumeng L, Li T. A Quantitative Trait Locus for Alcohol Consumption in Selectively Bred Rat Lines Alcoholism: Clinical and Experimental Research. 22: 884-887. DOI: 10.1111/J.1530-0277.1998.Tb03883.X  0.425
1998 Edenberg HJ, Reynolds J, Koller DL, Begleiter H, Bucholz KK, Conneally PM, Crowe R, Goate A, Hesselbrock V, Li T, Numberger JI, Porjesz B, Reich T, Rice JP, Schuckit M, et al. A Family-Based Analysis of Whether the Functional Promoter Alleles of the Serotonin Transporter Gene HTT Affect the Risk for Alcohol Dependence Alcoholism: Clinical and Experimental Research. 22: 1080-1085. DOI: 10.1111/J.1530-0277.1998.Tb03704.X  0.451
1998 Edenberg HJ, Foroud T, Koller DL, Goate A, Rice J, Eerdewegh P, Reich T, Cloninger CR, Nurnberger JI, Kowalczuk M, Wu B, Li T, Conneally PM, Tischfield JA, Wu W, et al. A Family-Based Analysis of the Association of the Dopamine D2 Receptor (DRD2) with Alcoholism Alcoholism: Clinical and Experimental Research. 22: 505-512. DOI: 10.1111/J.1530-0277.1998.Tb03680.X  0.456
1998 Foroud T, Bucholz KK, Edenberg HJ, Goate A, Neuman RJ, Porjesz B, Koller DL, Ric J, Reich T, Bierut LJ, Cloninger CR, Nurnberger JI, Li T, Conneally PM, Tischfield JA, et al. Linkage of an Alcoholism-Related Severity Phenotype to Chromosome 16 Alcoholism: Clinical and Experimental Research. 22: 2035-2042. DOI: 10.1097/00000374-199812000-00020  0.444
1998 Nurnberger J, Hesselbrock V, Crowe R, Porjesz B, Cloninger R, Schuckit M, O'Connor S, Bucholz K, Edenberg H, Goate A, Tischfield J, Foroud T, Rice J, Conneally P, Li T, et al. 241. The Collaborative Study of the genetics of alcoholism: Initial results and future goals Biological Psychiatry. 43: S71-S72. DOI: 10.1016/S0006-3223(98)90689-8  0.413
1997 Stine OC, McMahon FJ, Chen L, Xu J, Meyers DA, MacKinnon DF, Simpson S, McInnis MG, Rice JP, Goate A, Reich T, Edenberg HJ, Foroud T, Nurnberger JI, Detera-Wadleigh SD, et al. Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X. American Journal of Medical Genetics. 74: 263-9. PMID 9184308 DOI: 10.1002/(Sici)1096-8628(19970531)74:3<263::Aid-Ajmg5>3.0.Co;2-R  0.313
1997 Rice JP, Goate A, Williams JT, Bierut L, Dorr D, Wu W, Shears S, Gopalakrishnan G, Edenberg HJ, Foroud T, Nurnberger J, Gershon ES, Detera-Wadleigh SD, Goldin LR, Guroff JJ, et al. Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12. American Journal of Medical Genetics. 74: 247-53. PMID 9184306 DOI: 10.1002/(Sici)1096-8628(19970531)74:3<247::Aid-Ajmg3>3.0.Co;2-N  0.346
1997 Edenberg HJ, Foroud T, Conneally PM, Sorbel JJ, Carr K, Crose C, Willig C, Zhao J, Miller M, Bowman E, Mayeda A, Rau NL, Smiley C, Rice JP, Goate A, et al. Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 3, 5, 15, 16, 17, and 22. American Journal of Medical Genetics. 74: 238-46. PMID 9184305 DOI: 10.1002/(Sici)1096-8628(19970531)74:3<238::Aid-Ajmg2>3.0.Co;2-M  0.324
1997 Nurnberger JI, DePaulo JR, Gershon ES, Reich T, Blehar MC, Edenberg HJ, Foroud T, Miller M, Bowman E, Mayeda A, Rau NL, Smiley C, Conneally PM, McMahon F, Meyers D, et al. Genomic survey of bipolar illness in the NIMH genetics initiative pedigrees: A preliminary report American Journal of Medical Genetics - Neuropsychiatric Genetics. 74: 227-237. PMID 9184304 DOI: 10.1002/(Sici)1096-8628(19970531)74:3<227::Aid-Ajmg1>3.0.Co;2-N  0.323
1997 Chun KT, Edenberg HJ, Kelley MR, Goebl MG. Rapid amplification of uncharacterized transposon-tagged DNA sequences from genomic DNA Yeast. 13: 233-240. PMID 9090052 DOI: 10.1002/(Sici)1097-0061(19970315)13:3<233::Aid-Yea88>3.0.Co;2-E  0.314
1997 Edenberg HJ, Brown CJ, Hur MW, Kotagiri S, Li M, Zhang L, Zhi X. Regulation of the seven human alcohol dehydrogenase genes Advances in Experimental Medicine and Biology. 414: 339-345. PMID 9059638 DOI: 10.1007/978-1-4615-5871-2_39  0.385
1997 Shen Y, Fan J, Edenberg HJ, Li T, Cui Y, Wang Y, Tian C, Zhou C, Zhou R, Wang J, Zhao Z, Xia G. Polymorphism of ADH and ALDH Genes among Four Ethnic Groups in China and Effects upon the Risk for Alcoholism Alcoholism: Clinical and Experimental Research. 21: 1272-1277. DOI: 10.1111/J.1530-0277.1997.Tb04448.X  0.394
1996 Crabb DW, Edenberg HJ. Gene regulation of alcohol metabolizing enzymes Alcoholism: Clinical and Experimental Research. 20. PMID 8947247 DOI: 10.1111/J.1530-0277.1996.Tb01758.X  0.394
1996 Brown CJ, Zhang LU, Edenberg HJ. Gene expression in a young multigene family: Tissue-specific differences in the expression of the human alcohol dehydrogenase genes ADH1, ADH2, and ADH3 Dna and Cell Biology. 15: 187-196. PMID 8634148 DOI: 10.1089/Dna.1996.15.187  0.361
1995 Kedishvili NY, Bosron WF, Stone CL, Hurley TD, Peggs CF, Thomasson HR, Popov KM, Carr LG, Edenberg HJ, Li TK. Expression and kinetic characterization of recombinant human stomach alcohol dehydrogenase: Active-site amino acid sequence explains substrate specificity compared with liver isozymes Journal of Biological Chemistry. 270: 3625-3630. PMID 7876099 DOI: 10.1074/Jbc.270.8.3625  0.376
1995 Yu M, Edenberg HJ. Structure and Function of a Long Alternating Purine-Pyrimidine Sequence in the Mouse Alcohol Dehydrogenase Adh-1 Gene Archives of Biochemistry and Biophysics. 316: 407-412. PMID 7840644 DOI: 10.1006/Abbi.1995.1054  0.387
1995 Hur MW, Edenberg HJ. Cell-specific function of cis-acting elements in the regulation of human alcohol dehydrogenase 5 gene expression and effect of the 5′-nontranslated region Journal of Biological Chemistry. 270: 9002-9009. PMID 7721811 DOI: 10.1074/Jbc.270.15.9002  0.368
1995 Kedishvili NY, Bosron WF, Stone CL, Peggs CF, Thomasson HR, Popov KM, Carr LG, Hurley TD, Edenberg HJ, Li TK. Cloning and expression of a human stomach alcohol dehydrogenase isozyme Advances in Experimental Medicine and Biology. 372: 341-347. PMID 7484396 DOI: 10.1007/978-1-4615-1965-2_41  0.322
1995 Hur MW, Edenberg H. Erratum: Cell-specific function of cis-acting elements in the regulation of human alcohol dehydrogenase 5 gene expression and effect of the 5'- nontranslated region (Journal of Biological Chemistry (1995) 270 (9002- 9009)) Journal of Biological Chemistry. 270. DOI: 10.1074/Jbc.270.52.31414  0.413
1994 Brown CJ, Zhang L, Edenberg HJ. Tissue-specific differences in the expression of the human ADH2 alcohol dehydrogenase gene and in binding of factors to cis-acting elements in its promoter Dna and Cell Biology. 13: 235-247. PMID 8172654 DOI: 10.1089/Dna.1994.13.235  0.351
1994 Yu M, Jerome RE, Edenberg HJ. A negative regulatory element upstream from the mouse Adh-1 gene can down-regulate a heterologous promoter Gene. 141: 249-254. PMID 8163197 DOI: 10.1016/0378-1119(94)90580-0  0.348
1994 Thomasson HR, Crabb DW, Edenberg HJ, Li TK, Hwu HG, Chen CC, Yeh EK, Yin SJ. Low frequency of the ADH2*2 allele among Atayal natives of Taiwan with alcohol use disorders Alcoholism: Clinical and Experimental Research. 18: 640-643. PMID 7943668 DOI: 10.1111/J.1530-0277.1994.Tb00923.X  0.43
1993 Thomasson HR, Crabb DW, Edenberg HJ, Li TK. Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism Behavior Genetics. 23: 131-136. PMID 8512527 DOI: 10.1007/Bf01067417  0.417
1993 Edenberg HJ, Brown CJ, Zhang L. Regulation of the human alcohol dehydrogenase genes ADH1, ADH2 and ADH3: Differences in cis-acting sequences at CTF/NF-I sites Advances in Experimental Medicine and Biology. 328: 561-570. PMID 8493936 DOI: 10.1007/978-1-4615-2904-0_59  0.367
1992 Hur MW, Ho WH, Brown CJ, Goldman D, Edenberg HJ. Molecular cloning of mouse alcohol dehydrogenase-b2 cDNA: Nucleotide sequences of the class III ADH genes evolve slowly even for silent substitutions Mitochondrial Dna. 3: 167-175. PMID 1472709 DOI: 10.3109/10425179209034012  0.305
1992 Brown CJ, Baltz KA, Edenberg HJ. Expression of the human ADH2 gene: an unusual Sp1-binding site in the promoter of a gene expressed at high levels in liver Gene. 121: 313-320. PMID 1446829 DOI: 10.1016/0378-1119(92)90136-D  0.313
1992 Hur MW, Edenberg HJ. Cloning and characterization of the ADH5 gene encoding human alcohol dehydrogenase 5, formaldehyde dehydrogenase Gene. 121: 305-311. PMID 1446828 DOI: 10.1016/0378-1119(92)90135-C  0.413
1992 Edenberg HJ, Brown CJ. Regulation of human alcohol dehydrogenase genes Pharmacogenetics. 2: 185-196. PMID 1339084 DOI: 10.1097/00008571-199210000-00001  0.417
1991 Hurley TD, Ehrig T, Edenberg HJ, Bosron WF. Characterization of human alcohol dehydrogenases containing substitutions at amino acids 47 and 51 Advances in Experimental Medicine and Biology. 284: 271-275. PMID 2053482 DOI: 10.1007/978-1-4684-5901-2_29  0.314
1991 Edenberg HJ, Brown CJ, Carr LG, Ho WH, Hur MW. Alcohol dehydrogenase gene expression and cloning of the mouse χ-like ADH Advances in Experimental Medicine and Biology. 284: 253-262. PMID 2053480 DOI: 10.1007/978-1-4684-5901-2_27  0.423
1991 Thomasson HR, Edenberg HJ, Crabb DW, Mai XL, Jerome RE, Li TK, Wang SP, Lin YT, Lu RB, Yin SJ. Alcohol and aldehyde dehydrogenase genotypes and alcoholism in chinese men American Journal of Human Genetics. 48: 677-681. PMID 2014795  0.314
1991 Ehrig T, Hurley TD, Edenberg HJ, Bosron WF. General Base Catalysis in a Glutamine for Histidine Mutant at Position 51 of Human Liver Alcohol Dehydrogenase Biochemistry. 30: 1062-1068. PMID 1989677 DOI: 10.1021/Bi00218A026  0.341
1991 Day CP, Bashir R, James OFW, Bassendine MF, Crabb DW, Thomasson HR, Li TK, Edenberg HJ. Investigation of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol-related end-organ damage Hepatology. 14: 798-801. PMID 1937384 DOI: 10.1002/Hep.1840140509  0.404
1991 Harrington MA, Edenberg HJ, Saxman S, Pedigo LM, Daube R, Broxmeyer HE. Cloning and characterization of the murine promoter for the colony-stimulating factor-1-encoding gene Gene. 102: 165-170. PMID 1874443 DOI: 10.1016/0378-1119(91)90074-L  0.317
1991 Edenberg HJ. Expression of the human alcohol dehydrogenase genes Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 1: 79-83. PMID 1845597  0.35
1989 Carr LG, Ke Z, Edenberg HJ. Protein-DNA interactions in the 5′ region of the mouse alcohol dehydrogenase gene Adh-1 Gene. 78: 277-285. PMID 2777084 DOI: 10.1016/0378-1119(89)90230-8  0.371
1989 Carr LG, Xu Y, Ho WH, Edenberg HJ. Nucleotide sequence of the ADH23 gene encoding the human alcohol dehydrogenase β3 subunit Alcoholism: Clinical and Experimental Research. 13: 594-596. PMID 2679216 DOI: 10.1111/J.1530-0277.1989.Tb00383.X  0.359
1989 Crabb DW, Stein PM, Dipple KM, Hittle JB, Sidhu R, Qulali M, Zhang K, Edenberg HJ. Structure and expression of the rat class I alcohol dehydrogenase gene Genomics. 5: 906-914. PMID 2591969 DOI: 10.1016/0888-7543(89)90133-X  0.413
1989 Crabb DW, Edenberg HJ, Bosron WF, Li TK. Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH22 allele is dominant Journal of Clinical Investigation. 83: 314-316. PMID 2562960 DOI: 10.1172/Jci113875  0.399
1988 Xu Y, Carr LG, Bosron WF, Li TK, Edenberg HJ. Genotyping of human alcohol dehydrogenases at the ADH2 and ADH3 loci following DNA sequence amplification Genomics. 2: 209-214. PMID 3397059 DOI: 10.1016/0888-7543(88)90004-3  0.415
1987 Zhang K, Bosron WF, Edenberg HJ. Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity Gene. 57: 27-36. PMID 3428612 DOI: 10.1016/0378-1119(87)90173-9  0.334
1986 Crabb DW, Edenberg HJ. Complete amino acid sequence of rat liver alcohol dehydrogenase deduced from the cDNA sequence Gene. 48: 287-291. PMID 2881847 DOI: 10.1016/0378-1119(86)90087-9  0.322
1985 Edenberg HJ, Zhang K, Fong K, Bosron WF, Li TK. Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 82: 2262-2266. PMID 3157987 DOI: 10.1073/Pnas.82.8.2262  0.317
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