Year |
Citation |
Score |
2024 |
Dewenter M, Seitz T, Steinbrecher JH, Westenbrink BD, Ling H, Lehnart SE, Wehrens XHT, Backs J, Brown JH, Maier LS, Neef S. Ca2+/calmodulin-dependent kinase IIδC-induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak. Esc Heart Failure. PMID 38616546 DOI: 10.1002/ehf2.14772 |
0.311 |
|
2023 |
Grosch M, Schraft L, Chan A, Küchenhoff L, Rapti K, Ferreira AM, Kornienko J, Li S, Radke MH, Krämer C, Clauder-Münster S, Perlas E, Backs J, Gotthardt M, Dieterich C, et al. Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy. Nature Communications. 14: 3714. PMID 37349314 DOI: 10.1038/s41467-023-39352-1 |
0.303 |
|
2021 |
Werhahn SM, Kreusser JS, Hagenmüller M, Beckendorf J, Diemert N, Hoffmann S, Schultz JH, Backs J, Dewenter M. Adaptive versus maladaptive cardiac remodelling in response to sustained β-adrenergic stimulation in a new 'ISO on/off model'. Plos One. 16: e0248933. PMID 34138844 DOI: 10.1371/journal.pone.0248933 |
0.333 |
|
2021 |
Duran J, Nickel L, Estrada M, Backs J, van den Hoogenhof MMG. CaMKIIδ Splice Variants in the Healthy and Diseased Heart. Frontiers in Cell and Developmental Biology. 9: 644630. PMID 33777949 DOI: 10.3389/fcell.2021.644630 |
0.308 |
|
2021 |
Mustroph J, Sag CM, Bähr F, Schmidtmann AL, Gupta SN, Dietz A, Islam MT, Lücht CM, Beuthner BE, Pabel S, Baier MJ, El-Armouche A, Sossalla S, Anderson ME, Möllmann J, ... ... Backs J, et al. Loss of CASK Accelerates Heart Failure Development. Circulation Research. PMID 33593074 DOI: 10.1161/CIRCRESAHA.120.318170 |
0.359 |
|
2020 |
Schader T, Löwe O, Reschke C, Malacarne P, Hahner F, Müller N, Gajos-Draus A, Backs J, Schröder K. Oxidation of HDAC4 by Nox4-derived HO maintains tube formation by endothelial cells. Redox Biology. 36: 101669. PMID 32818796 DOI: 10.1016/J.Redox.2020.101669 |
0.314 |
|
2020 |
Lennermann D, Backs J, Hoogenhof MMGvd. New Insights in RBM20 Cardiomyopathy. Current Heart Failure Reports. 17: 234-246. PMID 32789749 DOI: 10.1007/S11897-020-00475-X |
0.361 |
|
2020 |
Jakobi T, Siede D, Eschenbach J, Heumüller AW, Busch M, Nietsch R, Meder B, Most P, Dimmeler S, Backs J, Katus HA, Dieterich C. Deep Characterization of Circular RNAs from Human Cardiovascular Cell Models and Cardiac Tissue. Cells. 9. PMID 32635460 DOI: 10.3390/Cells9071616 |
0.365 |
|
2020 |
He T, Huang J, Chen L, Han G, Stanmore D, Krebs-Haupenthal J, Avkiran M, Hagenmüller M, Backs J. Cyclic AMP represses pathological MEF2 activation by myocyte-specific hypo-phosphorylation of HDAC5. Journal of Molecular and Cellular Cardiology. PMID 32485181 DOI: 10.1016/J.Yjmcc.2020.05.018 |
0.436 |
|
2020 |
Zacchigna S, Paldino A, Falcão-Pires I, Daskalopoulos EP, Dal Ferro M, Vodret S, Lesizza P, Cannatà A, Miranda-Silva D, Lourenço AP, Pinamonti B, Sinagra G, Weinberger F, Eschenhagen T, Carrier L, ... ... Backs J, et al. Toward standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function. Cardiovascular Research. PMID 32365197 DOI: 10.1093/Cvr/Cvaa110 |
0.335 |
|
2020 |
Schäfer M, Oeing CU, Rohm M, Baysal-Temel E, Lehmann LH, Bauer R, Volz HC, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt MN, Eschenhagen T, ... ... Backs J, et al. 'Corrigendum to "Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia" [Molecular Metabolism 5 (2) (2015) 67-78]'. Molecular Metabolism. 35: 100970. PMID 32244184 DOI: 10.1016/J.Molmet.2020.02.013 |
0.327 |
|
2020 |
Kuhn TC, Knobel J, Burkert-Rettenmaier S, Li X, Meyer IS, Jungmann A, Sicklinger F, Backs J, Lasitschka F, Müller OJ, Katus HA, Krijgsveld J, Leuschner F. Secretome Analysis of Cardiomyocytes Identifies PCSK6 as a Novel Player in Cardiac Remodeling After Myocardial Infarction. Circulation. PMID 32100557 DOI: 10.1161/Circulationaha.119.044914 |
0.406 |
|
2020 |
Keramida K, Backs J, Bossone E, Citro R, Dawson D, Omerovic E, Parodi G, Schneider B, Ghadri JR, Van Laake LW, Lyon AR. Takotsubo syndrome in Heart Failure and World Congress on Acute Heart Failure 2019: highlights from the experts. Esc Heart Failure. PMID 31994355 DOI: 10.1002/Ehf2.12603 |
0.322 |
|
2019 |
Jebessa ZH, Shanmukha Kumar D, Dewenter M, Lehmann LH, Xu C, Schreiter F, Siede D, Gong XM, Worst BC, Federico G, Sauer SW, Fischer T, Wechselberger L, Müller OJ, Sossalla S, ... ... Backs J, et al. The lipid droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4. Nature Metabolism. 1: 1157-1167. PMID 31742248 DOI: 10.1038/s42255-019-0138-4 |
0.318 |
|
2019 |
Saadatmand AR, Sramek V, Weber S, Finke D, Dewenter M, Sticht C, Gretz N, Wüstemann T, Hagenmueller M, Kuenzel SR, Meyer-Roxlau S, Kramer M, Sossalla S, Lehmann LH, Kämmerer S, ... Backs J, et al. CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation. Proceedings of the National Academy of Sciences of the United States of America. 116: 22282-22287. PMID 31619570 DOI: 10.1073/Pnas.1816521116 |
0.425 |
|
2019 |
Doroudgar S, Hofmann C, Boileau E, Malone B, Riechert E, Gorska AA, Jakobi T, Sandmann C, Juergensen L, Kmietczyk V, Malovrh E, Burghaus J, Rettel M, Stein F, Younesi FS, ... ... Backs J, et al. Monitoring Cell Type-Specific Gene Expression Using Ribosome Profiling In Vivo During Cardiac Hemodynamic Stress. Circulation Research. PMID 31284834 DOI: 10.1161/Circresaha.119.314817 |
0.339 |
|
2019 |
Kronlage M, Dewenter M, Grosso J, Fleming T, Oehl UY, Lehmann LH, Falcão-Pires I, Leite-Moreira AF, Volk N, Gröne HJ, Müller OJ, Sickmann A, Katus HA, Backs J. O-GlcNAcylation of Histone Deacetylase 4 Protects the Diabetic Heart from Failure. Circulation. PMID 31195810 DOI: 10.1161/Circulationaha.117.031942 |
0.372 |
|
2019 |
Seferović PM, Polovina M, Bauersachs J, Arad M, Gal TB, Lund LH, Felix SB, Arbustini E, Caforio ALP, Farmakis D, Filippatos GS, Gialafos E, Kanjuh V, Krljanac G, Limongelli G, ... ... Backs J, et al. Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure. PMID 30989768 DOI: 10.1002/Ejhf.1461 |
0.361 |
|
2019 |
Triposkiadis F, Butler J, Abboud FM, Armstrong PW, Adamopoulos S, Atherton JJ, Backs J, Bauersachs J, Burkhoff D, Bonow RO, Chopra VK, de Boer RA, de Windt L, Hamdani N, Hasenfuss G, et al. The continuous heart failure spectrum: moving beyond an ejection fraction classification. European Heart Journal. PMID 30957868 DOI: 10.1093/Eurheartj/Ehz158 |
0.318 |
|
2019 |
Nickel AG, Kohlhaas M, Bertero E, Wilhelm D, Wagner M, Sequeira V, Kreusser MM, Dewenter M, Kappl R, Hoth M, Dudek J, Backs J, Maack C. CaMKII Does not Control Mitochondrial Ca Uptake in Cardiac Myocytes. The Journal of Physiology. PMID 30770570 DOI: 10.1113/Jp276766 |
0.365 |
|
2019 |
Schell R, Alban F, Haslinger C, Theis P, Katus HA, Backs J. Abstract 803: Sepsis-induced Acute Heart Failure is Driven by MEF2D-dependent Transcription Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.803 |
0.368 |
|
2018 |
Müller OJ, Heckmann MB, Ding L, Rapti K, Rangrez AY, Gerken T, Christiansen N, Rennefahrt UEE, Witt H, Maldonado SG, Ternes P, Schwab DM, Ruf T, Hille S, Remes A, ... ... Backs J, et al. Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure. Cardiovascular Research. PMID 30418544 DOI: 10.1093/Cvr/Cvy274 |
0.372 |
|
2018 |
Veltkamp R, Uhlmann S, Marinescu M, Sticht C, Finke D, Gretz N, Gröne HJ, Katus HA, Backs J, Lehmann LH. Experimental ischaemic stroke induces transient cardiac atrophy and dysfunction. Journal of Cachexia, Sarcopenia and Muscle. PMID 30378296 DOI: 10.1002/Jcsm.12335 |
0.357 |
|
2018 |
Maack C, Lehrke M, Backs J, Heinzel FR, Hulot JS, Marx N, Paulus WJ, Rossignol P, Taegtmeyer H, Bauersachs J, Bayes-Genis A, Brutsaert D, Bugger H, Clarke K, Cosentino F, et al. Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology. European Heart Journal. PMID 30295797 DOI: 10.1093/Eurheartj/Ehy596 |
0.314 |
|
2018 |
Tóth AD, Schell R, Lévay M, Vettel C, Theis P, Haslinger C, Alban F, Werhahn S, Frischbier L, Krebs-Haupenthal J, Thomas D, Gröne HJ, Avkiran M, Katus HA, Wieland T, ... Backs J, et al. Inflammation leads through PGE/EP signaling to HDAC5/MEF2-dependent transcription in cardiac myocytes. Embo Molecular Medicine. PMID 29907596 DOI: 10.15252/Emmm.201708536 |
0.441 |
|
2018 |
Beckendorf J, van den Hoogenhof MMG, Backs J. Physiological and unappreciated roles of CaMKII in the heart. Basic Research in Cardiology. 113: 29. PMID 29905892 DOI: 10.1007/S00395-018-0688-8 |
0.43 |
|
2018 |
van den Hoogenhof MMG, Beqqali A, Amin AS, van der Made I, Aufiero S, Khan MAF, Schumacher CA, Jansweijer JA, van Spaendonck-Zwarts KY, Remme CA, Backs J, Verkerk AO, Baartscheer A, Pinto YM, Creemers EE. RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling. Circulation. PMID 29650543 DOI: 10.1161/Circulationaha.117.031947 |
0.355 |
|
2018 |
Gomis-Coloma C, Velasco-Aviles S, Gomez-Sanchez JA, Casillas-Bajo A, Backs J, Cabedo H. Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells. The Journal of Cell Biology. PMID 29472387 DOI: 10.1083/Jcb.201611150 |
0.336 |
|
2018 |
Joos JP, Saadatmand AR, Schnabel C, Viktorinová I, Brand T, Kramer M, Nattel S, Dobrev D, Tomancak P, Backs J, Kleinbongard P, Heusch G, Lorenz K, Koch E, Weber S, et al. Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila. Scientific Reports. 8: 2940. PMID 29440697 DOI: 10.1038/S41598-018-21372-3 |
0.43 |
|
2018 |
Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, ... ... Backs J, et al. Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart. Circulation. PMID 29353241 DOI: 10.1161/Circulationaha.117.029733 |
0.362 |
|
2018 |
Gi WT, Haas J, Lai A, Sedaghat-Hamedani F, Kayvanpour E, Amr A, Frese K, Backs J, Keller A, Posch A, Katus H, Meder B. 4924DNA methylation regulates cardiac alternative splicing in DCM European Heart Journal. 39. DOI: 10.1093/Eurheartj/Ehy566.4924 |
0.338 |
|
2018 |
Mueller OJ, Heckmann MH, Ding L, Rapti K, Rangrez AY, Rennefahrt UEE, Ruf T, Jungmann A, Weis T, Kreusser J, Backs J, Frey N, Katus HA. P3760Comprehensive fingerprints of plasma, heart, liver, and muscle tissue disclose systemic metabolic alterations in cardiac hypertrophy and heart failure European Heart Journal. 39. DOI: 10.1093/Eurheartj/Ehy563.P3760 |
0.386 |
|
2017 |
Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, ... ... Backs J, et al. A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway. Nature Medicine. PMID 29227474 DOI: 10.1038/Nm.4452 |
0.477 |
|
2017 |
Sawall S, Franke D, Kirchherr A, Beckendorf J, Kuntz J, Maier J, Kraupner A, Backs J, Briel A, Kachelrieß M. In Vivo Quantification of Myocardial Infarction in Mice Using Micro-CT and a Novel Blood Pool Agent. Contrast Media & Molecular Imaging. 2017: 2617047. PMID 29114173 DOI: 10.1155/2017/2617047 |
0.316 |
|
2017 |
Dewenter M, von der Lieth A, Katus HA, Backs J. Calcium Signaling and Transcriptional Regulation in Cardiomyocytes. Circulation Research. 121: 1000-1020. PMID 28963192 DOI: 10.1161/Circresaha.117.310355 |
0.367 |
|
2017 |
Meder B, Haas J, Sedaghat-Hamedani F, Kayvanpour E, Frese K, Lai A, Nietsch R, Scheiner C, Mester S, Martins Bordalo D, Amr A, Dietrich C, Pils D, Siede D, Hund H, ... ... Backs J, et al. Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and A Novel Class of Biomarkers for Heart Failure. Circulation. PMID 28838933 DOI: 10.1161/Circulationaha.117.027355 |
0.405 |
|
2017 |
Schlegel P, Reinkober J, Meinhardt E, Tscheschner H, Gao E, Schumacher SM, Yuan A, Backs J, Most P, Wieland T, Koch WJ, Katus HA, Raake PW. G protein-coupled receptor kinase 2 promotes cardiac hypertrophy. Plos One. 12: e0182110. PMID 28759639 DOI: 10.1371/Journal.Pone.0182110 |
0.488 |
|
2017 |
Siede D, Rapti K, Gorska AA, Katus HA, Altmüller J, Boeckel JN, Meder B, Maack C, Völkers M, Müller OJ, Backs J, Dieterich C. Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease. Journal of Molecular and Cellular Cardiology. 109: 48-56. PMID 28676412 DOI: 10.1016/J.Yjmcc.2017.06.015 |
0.339 |
|
2017 |
Dewenter M, Neef S, Vettel C, Lämmle S, Beushausen C, Zelarayan LC, Katz S, von der Lieth A, Meyer-Roxlau S, Weber S, Wieland T, Sossalla S, Backs J, Brown JH, Maier LS, et al. Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure. Circulation. Heart Failure. 10: e003840. PMID 28487342 DOI: 10.1161/Circheartfailure.117.003840 |
0.352 |
|
2017 |
Neef S, Heijman J, Otte K, Dewenter M, Saadatmand AR, Meyer-Roxlau S, Antos CL, Backs J, Dobrev D, Wagner M, Maier LS, El-Armouche A. Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 28451724 DOI: 10.1007/S00210-017-1376-1 |
0.437 |
|
2017 |
Seyler C, Scherer D, Köpple C, Kulzer M, Korkmaz S, Xynogalos P, Thomas D, Kaya Z, Scholz E, Backs J, Karle C, Katus HA, Zitron E. Role of plasma membrane-associated AKAPs for the regulation of cardiac IK1 current by protein kinase A. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 28331977 DOI: 10.1007/S00210-017-1344-9 |
0.366 |
|
2016 |
Abu-Taha IH, Heijman J, Hippe HJ, Wolf NM, El-Armouche A, Nikolaev VO, Schäfer M, Würtz C, Neef S, Voigt N, Baczkó I, Varró A, Müller M, Meder B, Katus HA, ... ... Backs J, et al. Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure. Circulation. PMID 27927712 DOI: 10.1161/Circulationaha.116.022852 |
0.403 |
|
2016 |
Kreusser MM, Lehmann LH, Wolf N, Keranov S, Jungmann A, Gröne HJ, Müller OJ, Katus HA, Backs J. Inducible cardiomyocyte-specific deletion of CaM kinase II protects from pressure overload-induced heart failure. Basic Research in Cardiology. 111: 65. PMID 27683174 DOI: 10.1007/S00395-016-0581-2 |
0.465 |
|
2016 |
Scherer D, Seyler C, Xynogalos P, Scholz EP, Thomas D, Backs J, Andrassy M, Völkers M, Karle CA, Katus HA, Zitron E. Inhibition of Cardiac Kir Current (IK1) by Protein Kinase C Critically Depends on PKCβ and Kir2.2. Plos One. 11: e0156181. PMID 27214373 DOI: 10.1371/Journal.Pone.0156181 |
0.386 |
|
2016 |
Schäfer M, Oeing CU, Rohm M, Baysal-Temel E, Lehmann LH, Bauer R, Volz HC, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt MN, Eschenhagen T, ... ... Backs J, et al. Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia. Molecular Metabolism. 5: 67-78. PMID 26909315 DOI: 10.1016/J.Molmet.2015.11.004 |
0.304 |
|
2015 |
Spaich S, Zelniker T, Endres P, Stiepak J, Uhlmann L, Bekeredjian R, Chorianopoulos E, Giannitsis E, Backs J, Katus HA, Preusch MR. Fibroblast growth factor 23 (FGF-23) is an early predictor of mortality in patients with cardiac arrest. Resuscitation. PMID 26655587 DOI: 10.1016/J.Resuscitation.2015.11.012 |
0.329 |
|
2015 |
Saddouk FZ, Sun LY, Liu YF, Jiang M, Singer DV, Backs J, Van Riper D, Ginnan R, Schwarz JJ, Singer HA. Ca2+/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26567004 DOI: 10.1096/Fj.15-279158 |
0.671 |
|
2015 |
Mollova MY, Katus HA, Backs J. Regulation of CaMKII signaling in cardiovascular disease. Frontiers in Pharmacology. 6: 178. PMID 26379551 DOI: 10.3389/Fphar.2015.00178 |
0.478 |
|
2015 |
Spaich S, Katus HA, Backs J. Ongoing controversies surrounding cardiac remodeling: is it black and white-or rather fifty shades of gray? Frontiers in Physiology. 6: 202. PMID 26257654 DOI: 10.3389/Fphys.2015.00202 |
0.444 |
|
2015 |
Spinelli AM, Liu Y, Sun LY, González-Cobos JC, Backs J, Trebak M, Singer HA. Smooth muscle CaMKIIδ promotes allergen-induced airway hyperresponsiveness and inflammation. Pflugers Archiv : European Journal of Physiology. PMID 26089028 DOI: 10.1007/S00424-015-1713-5 |
0.375 |
|
2015 |
Zhang M, Hagenmueller M, Riffel JH, Kreusser MM, Bernhold E, Fan J, Katus HA, Backs J, Hardt SE. Calcium/calmodulin-dependent protein kinase II couples Wnt signaling with histone deacetylase 4 and mediates dishevelled-induced cardiomyopathy. Hypertension. 65: 335-44. PMID 25489064 DOI: 10.1161/Hypertensionaha.114.04467 |
0.476 |
|
2014 |
Fredman G, Ozcan L, Spolitu S, Hellmann J, Spite M, Backs J, Tabas I. Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway. Proceedings of the National Academy of Sciences of the United States of America. 111: 14530-5. PMID 25246560 DOI: 10.1073/Pnas.1410851111 |
0.343 |
|
2014 |
Lehmann LH, Rostosky JS, Buss SJ, Kreusser MM, Krebs J, Mier W, Enseleit F, Spiger K, Hardt SE, Wieland T, Haass M, Lüscher TF, Schneider MD, Parlato R, Gröne HJ, ... ... Backs J, et al. Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling. Proceedings of the National Academy of Sciences of the United States of America. 111: 13499-504. PMID 25197047 DOI: 10.1073/Pnas.1409026111 |
0.399 |
|
2014 |
Weinreuter M, Kreusser MM, Beckendorf J, Schreiter FC, Leuschner F, Lehmann LH, Hofmann KP, Rostosky JS, Diemert N, Xu C, Volz HC, Jungmann A, Nickel A, Sticht C, Gretz N, ... ... Backs J, et al. CaM Kinase II mediates maladaptive post-infarct remodeling and pro-inflammatory chemoattractant signaling but not acute myocardial ischemia/reperfusion injury. Embo Molecular Medicine. 6: 1231-45. PMID 25193973 DOI: 10.15252/Emmm.201403848 |
0.357 |
|
2014 |
Kreusser MM, Lehmann LH, Riffel JH, Haass M, Maser-Gluth C, Backs J, Katus HA, Buss SJ. Aldosterone augments Na+-induced reduction of cardiac norepinephrine reuptake. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1169-77. PMID 25128164 DOI: 10.1152/Ajpheart.00193.2014 |
0.359 |
|
2014 |
Kreusser MM, Lehmann LH, Keranov S, Hoting MO, Oehl U, Kohlhaas M, Reil JC, Neumann K, Schneider MD, Hill JA, Dobrev D, Maack C, Maier LS, Gröne HJ, Katus HA, ... ... Backs J, et al. Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy. Circulation. 130: 1262-73. PMID 25124496 DOI: 10.1161/Circulationaha.114.006185 |
0.57 |
|
2014 |
Werfel S, Jungmann A, Lehmann L, Ksienzyk J, Bekeredjian R, Kaya Z, Leuchs B, Nordheim A, Backs J, Engelhardt S, Katus HA, Müller OJ. Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase. Cardiovascular Research. 104: 15-23. PMID 25082846 DOI: 10.1093/Cvr/Cvu174 |
0.391 |
|
2014 |
Dybkova N, Wagner S, Backs J, Hund TJ, Mohler PJ, Sowa T, Nikolaev VO, Maier LS. Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa. Cardiovascular Research. 103: 168-77. PMID 24812278 DOI: 10.1093/Cvr/Cvu120 |
0.379 |
|
2014 |
Kreusser MM, Backs J. Integrated mechanisms of CaMKII-dependent ventricular remodeling. Frontiers in Pharmacology. 5: 36. PMID 24659967 DOI: 10.3389/Fphar.2014.00036 |
0.497 |
|
2014 |
Lehmann LH, Stanmore DA, Backs J. The role of endothelin-1 in the sympathetic nervous system in the heart. Life Sciences. 118: 165-72. PMID 24632477 DOI: 10.1016/J.Lfs.2014.03.005 |
0.357 |
|
2014 |
Lehmann LH, Worst BC, Stanmore DA, Backs J. Histone deacetylase signaling in cardioprotection. Cellular and Molecular Life Sciences : Cmls. 71: 1673-90. PMID 24310814 DOI: 10.1007/S00018-013-1516-9 |
0.408 |
|
2014 |
Seyler C, Scherer D, Koepple C, Kulzer M, Korkmaz S, Thomas D, Kaya Z, Backs J, Katus H, Zitron E. P107Role of plasma membrane-associated AKAPs 15/18 and 79 for the regulation of cardiac IK1 current by protein kinase A Cardiovascular Research. 103: S18.3-S18. DOI: 10.1093/Cvr/Cvu082.48 |
0.374 |
|
2013 |
Ozcan L, Cristina de Souza J, Harari AA, Backs J, Olson EN, Tabas I. Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling. Cell Metabolism. 18: 803-15. PMID 24268736 DOI: 10.1016/J.Cmet.2013.10.011 |
0.435 |
|
2013 |
Scott JA, Klutho PJ, El Accaoui R, Nguyen E, Venema AN, Xie L, Jiang S, Dibbern M, Scroggins S, Prasad AM, Luczak ED, Davis MK, Li W, Guan X, Backs J, et al. The multifunctional Ca²⁺/calmodulin-dependent kinase IIδ (CaMKIIδ) regulates arteriogenesis in a mouse model of flow-mediated remodeling. Plos One. 8: e71550. PMID 23951185 DOI: 10.1371/Journal.Pone.0071550 |
0.327 |
|
2013 |
Neef S, Sag CM, Daut M, Bäumer H, Grefe C, El-Armouche A, DeSantiago J, Pereira L, Bers DM, Backs J, Maier LS. While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice. Journal of Molecular and Cellular Cardiology. 59: 107-16. PMID 23473775 DOI: 10.1016/J.Yjmcc.2013.02.014 |
0.399 |
|
2013 |
Hohl M, Wagner M, Reil JC, Müller SA, Tauchnitz M, Zimmer AM, Lehmann LH, Thiel G, Böhm M, Backs J, Maack C. HDAC4 controls histone methylation in response to elevated cardiac load. The Journal of Clinical Investigation. 123: 1359-70. PMID 23434587 DOI: 10.1172/Jci61084 |
0.419 |
|
2013 |
Haas J, Frese KS, Park YJ, Keller A, Vogel B, Lindroth AM, Weichenhan D, Franke J, Fischer S, Bauer A, Marquart S, Sedaghat-Hamedani F, Kayvanpour E, Köhler D, Wolf NM, ... ... Backs J, et al. Alterations in cardiac DNA methylation in human dilated cardiomyopathy. Embo Molecular Medicine. 5: 413-29. PMID 23341106 DOI: 10.1002/Emmm.201201553 |
0.381 |
|
2013 |
Hamdani N, Krysiak J, Kreusser MM, Neef S, Dos Remedios CG, Maier LS, Krüger M, Backs J, Linke WA. Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation. Circulation Research. 112: 664-74. PMID 23283722 DOI: 10.1161/Circresaha.111.300105 |
0.438 |
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2013 |
Reinkober J, Tscheschner H, Schlegel P, Wieland T, Backs J, Koch W, Katus H, Most P, Raake P. G-protein coupled receptor kinase 2 (GRK-2), a new regulator in the pathological cardiac hypertrophy by interacting NFAT signaling European Heart Journal. 34: 39-39. DOI: 10.1093/Eurheartj/Eht307.39 |
0.364 |
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2013 |
Hamdani N, Krysiak J, Kreusser MM, Neef S, Remedios Cd, Maier LS, Backs J, Krüger M, Linke WA. Crucial Role for Ca2+/Calmodulin-Dependent Protein Kinase-II Delta in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.129 |
0.456 |
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2012 |
Spaich S, Will RD, Just S, Spaich S, Kuhn C, Frank D, Berger IM, Wiemann S, Korn B, Koegl M, Backs J, Katus HA, Rottbauer W, Frey N. F-box and leucine-rich repeat protein 22 is a cardiac-enriched F-box protein that regulates sarcomeric protein turnover and is essential for maintenance of contractile function in vivo. Circulation Research. 111: 1504-16. PMID 22972877 DOI: 10.1161/Circresaha.112.271007 |
0.405 |
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2012 |
Scott JA, Xie L, Li H, Li W, He JB, Sanders PN, Carter AB, Backs J, Anderson ME, Grumbach IM. The multifunctional Ca2+/calmodulin-dependent kinase II regulates vascular smooth muscle migration through matrix metalloproteinase 9. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1953-64. PMID 22427508 DOI: 10.1152/Ajpheart.00978.2011 |
0.346 |
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2012 |
Kuhn C, Frank D, Dierck F, Oehl U, Krebs J, Will R, Lehmann LH, Backs J, Katus HA, Frey N. Cardiac remodeling is not modulated by overexpression of muscle LIM protein (MLP). Basic Research in Cardiology. 107: 262. PMID 22421737 DOI: 10.1007/S00395-012-0262-8 |
0.466 |
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2011 |
Backs J, Worst BC, Lehmann LH, Patrick DM, Jebessa Z, Kreusser MM, Sun Q, Chen L, Heft C, Katus HA, Olson EN. Selective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4. The Journal of Cell Biology. 195: 403-15. PMID 22042619 DOI: 10.1083/Jcb.201105063 |
0.544 |
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2011 |
Sag CM, Köhler AC, Anderson ME, Backs J, Maier LS. CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes. Journal of Molecular and Cellular Cardiology. 51: 749-59. PMID 21819992 DOI: 10.1016/J.Yjmcc.2011.07.016 |
0.338 |
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2011 |
Just S, Berger IM, Meder B, Backs J, Keller A, Marquart S, Frese K, Patzel E, Rauch GJ, Katus HA, Rottbauer W. Protein kinase D2 controls cardiac valve formation in zebrafish by regulating histone deacetylase 5 activity. Circulation. 124: 324-34. PMID 21730303 DOI: 10.1161/Circulationaha.110.003301 |
0.419 |
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2011 |
Berry JM, Le V, Rotter D, Battiprolu PK, Grinsfelder B, Tannous P, Burchfield JS, Czubryt M, Backs J, Olson EN, Rothermel BA, Hill JA. Reversibility of adverse, calcineurin-dependent cardiac remodeling. Circulation Research. 109: 407-17. PMID 21700928 DOI: 10.1161/Circresaha.110.228452 |
0.571 |
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2011 |
Wagner S, Ruff HM, Weber SL, Bellmann S, Sowa T, Schulte T, Anderson ME, Grandi E, Bers DM, Backs J, Belardinelli L, Maier LS. Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload. Circulation Research. 108: 555-65. PMID 21252154 DOI: 10.1161/Circresaha.110.221911 |
0.326 |
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2011 |
Li W, Li H, Sanders PN, Mohler PJ, Backs J, Olson EN, Anderson ME, Grumbach IM. The multifunctional Ca2+/calmodulin-dependent kinase II delta (CaMKIIdelta) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21. The Journal of Biological Chemistry. 286: 7990-9. PMID 21193397 DOI: 10.1074/Jbc.M110.163006 |
0.518 |
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2011 |
Toischer K, Rokita AG, Unsöld B, Sossalla S, Becker A, Seidler T, Grebe C, Preuß L, Gupta SN, Schmidt K, Lehnart SE, Schäfer K, Maier LS, Hasenfuss G, Zhu W, ... ... Backs J, et al. Response to letter regarding article, "differential Cardiac Remodeling in Preload Versus Afterload" Circulation. 123: e421. DOI: 10.1161/Circulationaha.110.017566 |
0.321 |
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2010 |
Moresi V, Williams AH, Meadows E, Flynn JM, Potthoff MJ, McAnally J, Shelton JM, Backs J, Klein WH, Richardson JA, Bassel-Duby R, Olson EN. Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases. Cell. 143: 35-45. PMID 20887891 DOI: 10.1016/J.Cell.2010.09.004 |
0.663 |
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2010 |
Toischer K, Rokita AG, Unsöld B, Zhu W, Kararigas G, Sossalla S, Reuter SP, Becker A, Teucher N, Seidler T, Grebe C, Preuss L, Gupta SN, Schmidt K, Lehnart SE, ... ... Backs J, et al. Differential cardiac remodeling in preload versus afterload. Circulation. 122: 993-1003. PMID 20733099 DOI: 10.1161/Circulationaha.110.943431 |
0.349 |
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2010 |
Kristen AV, Schuhmacher B, Strych K, Lossnitzer D, Friederich HC, Hilbel T, Haass M, Katus HA, Schneider A, Streitberger KM, Backs J. Acupuncture improves exercise tolerance of patients with heart failure: a placebo-controlled pilot study. Heart (British Cardiac Society). 96: 1396-400. PMID 20554511 DOI: 10.1136/Hrt.2009.187930 |
0.359 |
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2010 |
Xu L, Lai D, Cheng J, Lim HJ, Keskanokwong T, Backs J, Olson EN, Wang Y. Alterations of L-type calcium current and cardiac function in CaMKII{delta} knockout mice. Circulation Research. 107: 398-407. PMID 20538682 DOI: 10.1161/Circresaha.110.222562 |
0.504 |
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2010 |
Backs J, Stein P, Backs T, Duncan FE, Grueter CE, McAnally J, Qi X, Schultz RM, Olson EN. The γ isoform of CaM kinase II controls mouse egg activation by regulating cell cycle resumption Proceedings of the National Academy of Sciences of the United States of America. 107: 81-86. PMID 19966304 DOI: 10.1073/Pnas.0912658106 |
0.487 |
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2009 |
Sag CM, Wadsack DP, Khabbazzadeh S, Abesser M, Grefe C, Neumann K, Opiela MK, Backs J, Olson EN, Brown JH, Neef S, Maier SK, Maier LS. Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure. Circulation. Heart Failure. 2: 664-75. PMID 19919992 DOI: 10.1161/Circheartfailure.109.865279 |
0.543 |
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2009 |
Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, Tabas I. Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. The Journal of Clinical Investigation. 119: 2925-41. PMID 19741297 DOI: 10.1172/Jci38857 |
0.445 |
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2009 |
Backs J, Backs T, Neef S, Kreusser MM, Lehmann LH, Patrick DM, Grueter CE, Qi X, Richardson JA, Hill JA, Katus HA, Bassel-Duby R, Maier LS, Olson EN. The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proceedings of the National Academy of Sciences of the United States of America. 106: 2342-7. PMID 19179290 DOI: 10.1073/Pnas.0813013106 |
0.595 |
|
2009 |
Stein P, Backs T, Backs J, Duncan FE, McAnally J, Qi X, Schultz RM, Olson EN. Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Gamma Is the Main Integrator of Calcium Signaling at Fertilization in the Mouse. Biology of Reproduction. 81: 132-132. DOI: 10.1093/Biolreprod/81.S1.132 |
0.452 |
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2008 |
Backs J, Backs T, Bezprozvannaya S, McKinsey TA, Olson EN. Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4. Molecular and Cellular Biology. 28: 3437-45. PMID 18332106 DOI: 10.1128/Mcb.01611-07 |
0.514 |
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2008 |
Kreusser MM, Buss SJ, Krebs J, Kinscherf R, Metz J, Katus HA, Haass M, Backs J. Differential expression of cardiac neurotrophic factors and sympathetic nerve ending abnormalities within the failing heart. Journal of Molecular and Cellular Cardiology. 44: 380-7. PMID 18037433 DOI: 10.1016/J.Yjmcc.2007.10.019 |
0.367 |
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2007 |
Zhang T, Kohlhaas M, Backs J, Mishra S, Phillips W, Dybkova N, Chang S, Ling H, Bers DM, Maier LS, Olson EN, Brown JH. CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses. The Journal of Biological Chemistry. 282: 35078-87. PMID 17923476 DOI: 10.1074/Jbc.M707083200 |
0.566 |
|
2007 |
Potthoff MJ, Wu H, Arnold MA, Shelton JM, Backs J, McAnally J, Richardson JA, Bassel-Duby R, Olson EN. Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. The Journal of Clinical Investigation. 117: 2459-67. PMID 17786239 DOI: 10.1172/Jci31960 |
0.687 |
|
2006 |
Olson EN, Backs J, McKinsey TA. Control of cardiac hypertrophy and heart failure by histone acetylation/deacetylation. Novartis Foundation Symposium. 274: 3-12; discussion 13-. PMID 17019803 DOI: 10.1002/0470029331.Ch2 |
0.586 |
|
2006 |
Kristen AV, Kreusser MM, Lehmann L, Kinscherf R, Katus HA, Haass M, Backs J. Preserved norepinephrine reuptake but reduced sympathetic nerve endings in hypertrophic volume-overloaded rat hearts. Journal of Cardiac Failure. 12: 577-83. PMID 16952792 DOI: 10.1016/J.Cardfail.2006.05.006 |
0.399 |
|
2006 |
Backs J, Song K, Bezprozvannaya S, Chang S, Olson EN. CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. The Journal of Clinical Investigation. 116: 1853-64. PMID 16767219 DOI: 10.1172/Jci27438 |
0.54 |
|
2006 |
Song K, Backs J, McAnally J, Qi X, Gerard RD, Richardson JA, Hill JA, Bassel-Duby R, Olson EN. The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. Cell. 125: 453-66. PMID 16678093 DOI: 10.1016/J.Cell.2006.02.048 |
0.564 |
|
2006 |
Buss SJ, Backs J, Kreusser MM, Hardt SE, Maser-Gluth C, Katus HA, Haass M. Spironolactone preserves cardiac norepinephrine reuptake in salt-sensitive Dahl rats. Endocrinology. 147: 2526-34. PMID 16439456 DOI: 10.1210/En.2005-1167 |
0.41 |
|
2006 |
Backs J, Olson EN. Control of cardiac growth by histone acetylation/deacetylation. Circulation Research. 98: 15-24. PMID 16397154 DOI: 10.1161/01.Res.0000197782.21444.8F |
0.514 |
|
2006 |
Kreusser MM, Haass M, Buss SJ, Hardt SE, Gerber SH, Kinscherf R, Katus HA, Backs J. Injection of nerve growth factor into stellate ganglia improves norepinephrine reuptake into failing hearts. Hypertension. 47: 209-15. PMID 16380518 DOI: 10.1161/01.Hyp.0000200157.25792.26 |
0.387 |
|
2005 |
Backs J, Bresch E, Lutz M, Kristen AV, Haass M. Endothelin-1 inhibits the neuronal norepinephrine transporter in hearts of male rats. Cardiovascular Research. 67: 283-90. PMID 16005303 DOI: 10.1016/J.Cardiores.2005.03.018 |
0.379 |
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2003 |
Zugck C, Lossnitzer D, Backs J, Kristen A, Kinscherf R, Haass M. Increased cardiac norepinephrine release in spontaneously hypertensive rats: role of presynaptic alpha-2A adrenoceptors. Journal of Hypertension. 21: 1363-9. PMID 12817185 DOI: 10.1097/00004872-200307000-00026 |
0.335 |
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2001 |
Backs J, Haunstetter A, Gerber SH, Metz J, Borst MM, Strasser RH, Kübler W, Haass M. The neuronal norepinephrine transporter in experimental heart failure: evidence for a posttranscriptional downregulation. Journal of Molecular and Cellular Cardiology. 33: 461-72. PMID 11181015 DOI: 10.1006/Jmcc.2000.1319 |
0.394 |
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