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Gentry N. Patrick - Publications

Affiliations: 
Neurobiology University of California, San Diego, La Jolla, CA 
Area:
Ubiquitin Proteasome System, Neurodegenerative Disease
Website:
http://biology.ucsd.edu/faculty/patrick.html

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lawrence JA, Aguilar-Calvo P, Ojeda-Juárez D, Khuu H, Soldau K, Pizzo DP, Wang J, Malik A, Shay TF, Sullivan EE, Aulston B, Song SM, Callender JA, Sanchez H, Geschwind MD, ... ... Patrick GN, et al. Diminished neuronal ESCRT-0 function exacerbates AMPA receptor derangement and accelerates prion-induced neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37019623 DOI: 10.1523/JNEUROSCI.1878-22.2023  0.426
2022 Lordén G, Wozniak JM, Doré K, Dozier LE, Cates-Gatto C, Patrick GN, Gonzalez DJ, Roberts AJ, Tanzi RE, Newton AC. Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model. Nature Communications. 13: 7200. PMID 36418293 DOI: 10.1038/s41467-022-34679-7  0.324
2022 Ojeda-Juarez D, Lawrence J, Soldau K, Pizzo D, Wheeler E, Aguilar-Calvo P, Khuu H, Chen J, Malik A, Funk G, Nam T, Sanchez H, Geschwind MD, Wu C, Yeo GW, ... ... Patrick GN, et al. Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus. Neurobiology of Disease. 105834. PMID 35905927 DOI: 10.1016/j.nbd.2022.105834  0.352
2021 Scudder SL, Gonzales FR, Howell KK, Stein IS, Dozier LE, Anagnostaras SG, Zito K, Patrick GN. Altered phosphorylation of the proteasome subunit Rpt6 has minimal impact on synaptic plasticity and learning. Eneuro. PMID 33658307 DOI: 10.1523/ENEURO.0073-20.2021  0.842
2017 Gonzales FR, Howell KK, Dozier LE, Anagnostaras SG, Patrick GN. Proteasome phosphorylation regulates cocaine-induced sensitization. Molecular and Cellular Neurosciences. PMID 29217409 DOI: 10.1016/J.Mcn.2017.12.001  0.382
2017 Marquez-Lona EM, Torres-Machorro AL, Gonzales FR, Pillus L, Patrick GN. Phosphorylation of the 19S regulatory particle ATPase subunit, Rpt6, modifies susceptibility to proteotoxic stress and protein aggregation. Plos One. 12: e0179893. PMID 28662109 DOI: 10.1371/Journal.Pone.0179893  0.471
2017 Goo MS, Sancho L, Slepak N, Boassa D, Deerinck TJ, Ellisman MH, Bloodgood BL, Patrick GN. Activity-dependent trafficking of lysosomes in dendrites and dendritic spines. The Journal of Cell Biology. PMID 28630145 DOI: 10.1083/Jcb.201704068  0.555
2017 Dwyer CA, Scudder SL, Lin Y, Dozier LE, Phan D, Allen NJ, Patrick GN, Esko JD. Neurodevelopmental Changes in Excitatory Synaptic Structure and Function in the Cerebral Cortex of Sanfilippo Syndrome IIIA Mice. Scientific Reports. 7: 46576. PMID 28418018 DOI: 10.1038/Srep46576  0.786
2016 Cifelli JL, Dozier L, Chung T, Patrick GN, Yang J. Benzothiazole Amphiphiles Promote the Formation of Dendritic Spines in Primary Hippocampal Neurons. The Journal of Biological Chemistry. PMID 27022020 DOI: 10.1074/Jbc.M115.701482  0.476
2016 Rodrigues EM, Scudder SL, Goo MS, Patrick GN. Aβ-Induced Synaptic Alterations Require the E3 Ubiquitin Ligase Nedd4-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1590-5. PMID 26843640 DOI: 10.1523/Jneurosci.2964-15.2016  0.815
2015 Goo MS, Scudder SL, Patrick GN. Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptors. Frontiers in Molecular Neuroscience. 8: 60. PMID 26528125 DOI: 10.3389/Fnmol.2015.00060  0.805
2015 Scudder SL, Patrick GN. Synaptic structure and function are altered by the neddylation inhibitor MLN4924. Molecular and Cellular Neurosciences. 65: 52-7. PMID 25701678 DOI: 10.1016/J.Mcn.2015.02.010  0.841
2014 Scudder SL, Goo MS, Cartier AE, Molteni A, Schwarz LA, Wright R, Patrick GN. Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16637-49. PMID 25505317 DOI: 10.1523/Jneurosci.2452-14.2014  0.83
2012 Hamilton AM, Oh WC, Vega-Ramirez H, Stein IS, Hell JW, Patrick GN, Zito K. Activity-dependent growth of new dendritic spines is regulated by the proteasome. Neuron. 74: 1023-30. PMID 22726833 DOI: 10.1016/J.Neuron.2012.04.031  0.529
2012 Cartier AE, Ubhi K, Spencer B, Vazquez-Roque RA, Kosberg KA, Fourgeaud L, Kanayson P, Patrick C, Rockenstein E, Patrick GN, Masliah E. Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy. Plos One. 7: e34713. PMID 22514658 DOI: 10.1371/Journal.Pone.0034713  0.385
2012 Djakovic SN, Marquez-Lona EM, Jakawich SK, Wright R, Chu C, Sutton MA, Patrick GN. Phosphorylation of Rpt6 regulates synaptic strength in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5126-31. PMID 22496558 DOI: 10.1523/Jneurosci.4427-11.2012  0.761
2012 Schwarz LA, Patrick GN. Ubiquitin-dependent endocytosis, trafficking and turnover of neuronal membrane proteins. Molecular and Cellular Neurosciences. 49: 387-93. PMID 21884797 DOI: 10.1016/j.mcn.2011.08.006  0.654
2010 Schwarz LA, Hall BJ, Patrick GN. Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16718-29. PMID 21148011 DOI: 10.1523/JNEUROSCI.3686-10.2010  0.708
2010 Keil JM, Shen Z, Briggs SP, Patrick GN. Regulation of STIM1 and SOCE by the ubiquitin-proteasome system (UPS). Plos One. 5: e13465. PMID 20976103 DOI: 10.1371/Journal.Pone.0013465  0.793
2010 Jakawich SK, Neely RM, Djakovic SN, Patrick GN, Sutton MA. An essential postsynaptic role for the ubiquitin proteasome system in slow homeostatic synaptic plasticity in cultured hippocampal neurons. Neuroscience. 171: 1016-31. PMID 20888892 DOI: 10.1016/J.Neuroscience.2010.09.061  0.76
2009 Djakovic SN, Schwarz LA, Barylko B, DeMartino GN, Patrick GN. Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 284: 26655-65. PMID 19638347 DOI: 10.1074/jbc.M109.021956  0.834
2009 Cartier AE, Djakovic SN, Salehi A, Wilson SM, Masliah E, Patrick GN. Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7857-68. PMID 19535597 DOI: 10.1523/Jneurosci.1817-09.2009  0.784
2009 Kerjan G, Koizumi H, Han EB, Dubé CM, Djakovic SN, Patrick GN, Baram TZ, Heinemann SF, Gleeson JG. Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures. Proceedings of the National Academy of Sciences of the United States of America. 106: 6766-71. PMID 19342486 DOI: 10.1073/Pnas.0812687106  0.737
2006 Patrick GN. Synapse formation and plasticity: recent insights from the perspective of the ubiquitin proteasome system. Current Opinion in Neurobiology. 16: 90-4. PMID 16427269 DOI: 10.1016/j.conb.2006.01.007  0.589
2004 Smith WB, Bingol B, Patrick GN, Schuman EM. 15 Control of Synaptic Function by Local Protein Synthesis and Degradation Cold Spring Harbor Monograph Archive. 42: 473-507. DOI: 10.1101/087969672.42.473  0.824
2003 Patrick GN, Bingol B, Weld HA, Schuman EM. Ubiquitin-mediated proteasome activity is required for agonist-induced endocytosis of GluRs. Current Biology : Cb. 13: 2073-81. PMID 14653997 DOI: 10.1016/j.cub.2003.10.028  0.835
2001 Patrick GN, Zukerberg L, Nikolic M, de La Monte S, Dikkes P, Tsai LH. reply: Neurobiologyp25 protein in neurodegeneration. Nature. 411: 764-765. PMID 11460109 DOI: 10.1038/35081149  0.466
2001 Patrick GN, Zukerberg L, Nikolic M, De La Monte S, Dikkes P, Tsai LH. P25 protein in neurodegeneration Nature. 411: 763-765. PMID 11459045  0.401
2000 Zukerberg LR, Patrick GN, Nikolic M, Humbert S, Wu CL, Lanier LM, Gertler FB, Vidal M, Van Etten RA, Tsai LH. Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron. 26: 633-46. PMID 10896159 DOI: 10.1016/S0896-6273(00)81200-3  0.546
1999 Patrick GN, Zukerberg L, Nikolic M, de la Monte S, Dikkes P, Tsai LH. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature. 402: 615-22. PMID 10604467 DOI: 10.1038/45159  0.54
1999 Huang D, Patrick G, Moffat J, Tsai LH, Andrews B. Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 14445-50. PMID 10588725 DOI: 10.1073/Pnas.96.25.14445  0.594
1998 Patrick GN, Zhou P, Kwon YT, Howley PM, Tsai LH. p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 273: 24057-64. PMID 9727024 DOI: 10.1074/Jbc.273.37.24057  0.57
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