Cecilia Canessa - Publications

Affiliations: 
Yale University School of Medicine, New Haven, CT 
Area:
ASIC channels
Website:
http://www.med.yale.edu/cmphysiol/faculty/facultypages/canessa.html

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chen Z, Kuenze G, Meiler J, Canessa CM. An arginine residue in the outer segment of hASIC1a TM1 affects both proton affinity and channel desensitization. The Journal of General Physiology. 153. PMID 33851970 DOI: 10.1085/jgp.202012802  0.306
2019 Wu Y, Chen Z, Canessa C. A Mechanism for Desensitization of all Three Functional Mammalian Acid Sensing Ion Channels Biophysical Journal. 116: 36a. DOI: 10.1016/J.BPJ.2018.11.237  0.416
2014 Li T, Yang Y, Canessa CM. A method for activation of endogenous acid-sensing ion channel 1a (ASIC1a) in the nervous system with high spatial and temporal precision. The Journal of Biological Chemistry. 289: 15441-8. PMID 24727474 DOI: 10.1074/Jbc.M114.550012  0.319
2013 Hernández-Díaz I, Giraldez T, Morales S, Hernandez G, Salido E, Canessa CM, Alvarez de la Rosa D. Heterogeneous nuclear ribonucleoprotein A2/B1 is a tissue-specific aldosterone target gene with prominent induction in the rat distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G122-31. PMID 23139218 DOI: 10.1152/Ajpgi.00130.2012  0.751
2011 Li T, Yang Y, Canessa CM. Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1. Nature Communications. 2: 399. PMID 21772270 DOI: 10.1038/Ncomms1409  0.33
2011 Li T, Yang Y, Canessa C. D433 Does Not Determine Ion Selectivity in ASIC1 Biophysical Journal. 100: 25a. DOI: 10.1016/J.Bpj.2010.12.343  0.401
2010 Li T, Yang Y, Canessa CM. Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation. The Journal of Biological Chemistry. 285: 22706-12. PMID 20479002 DOI: 10.1074/Jbc.M110.134114  0.376
2010 Li T, Yang Y, Canessa CM. Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel. American Journal of Physiology. Cell Physiology. 299: C66-73. PMID 20427715 DOI: 10.1152/Ajpcell.00100.2010  0.347
2008 Arteaga MF, Coric T, Straub C, Canessa CM. A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 4459-64. PMID 18334630 DOI: 10.1073/pnas.0800958105  0.306
2008 Coric T, Passamaneck YJ, Zhang P, Di Gregorio A, Canessa CM. Simple chordates exhibit a proton-independent function of acid-sensing ion channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1914-23. PMID 18211956 DOI: 10.1096/fj.07-100313  0.342
2007 Arteaga MF, Alvarez de la Rosa D, Alvarez JA, Canessa CM. Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1. Molecular Biology of the Cell. 18: 2072-80. PMID 17377066 DOI: 10.1091/mbc.E06-10-0968  0.764
2006 Arteaga MF, Wang L, Ravid T, Hochstrasser M, Canessa CM. An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proceedings of the National Academy of Sciences of the United States of America. 103: 11178-83. PMID 16847254 DOI: 10.1073/Pnas.0604816103  0.317
2006 Zhang P, Sigworth FJ, Canessa CM. Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism. The Journal of General Physiology. 127: 109-17. PMID 16418400 DOI: 10.1085/Jgp.200509396  0.347
2006 Leng Q, Kahle KT, Rinehart J, MacGregor GG, Wilson FH, Canessa CM, Lifton RP, Hebert SC. WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1). The Journal of Physiology. 571: 275-86. PMID 16357011 DOI: 10.1113/Jphysiol.2005.102202  0.449
2006 Alvarez de la Rosa D, Gimenez I, Forbush B, Canessa CM. SGK1 activates Na+-K+-ATPase in amphibian renal epithelial cells. American Journal of Physiology. Cell Physiology. 290: C492-8. PMID 16192298 DOI: 10.1152/ajpcell.00556.2004  0.769
2005 Todorović N, Corić T, Zhang P, Canessa C. Effects of extracellular calcium on fASIC1 currents. Annals of the New York Academy of Sciences. 1048: 331-6. PMID 16154945 DOI: 10.1196/annals.1342.030  0.316
2005 Coric T, Zheng D, Gerstein M, Canessa CM. Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel. The Journal of Physiology. 568: 725-35. PMID 16002453 DOI: 10.1113/Jphysiol.2005.087734  0.367
2005 Arteaga MF, Canessa CM. Functional specificity of Sgk1 and Akt1 on ENaC activity. American Journal of Physiology. Renal Physiology. 289: F90-6. PMID 15951481 DOI: 10.1152/ajprenal.00390.2004  0.399
2005 Zhang YH, Alvarez de la Rosa D, Canessa CM, Hayslett JP. Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells. American Journal of Physiology. Cell Physiology. 288: C141-7. PMID 15355850 DOI: 10.1152/ajpcell.00343.2004  0.774
2004 Alvarez de la Rosa D, Paunescu TG, Els WJ, Helman SI, Canessa CM. Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells. The Journal of General Physiology. 124: 395-407. PMID 15452200 DOI: 10.1085/jgp.200409120  0.801
2004 Mobasheri A, Critchlow K, Clegg PD, Carter SD, Canessa CM. Chronic equine laminitis is characterised by loss of GLUT1, GLUT4 and ENaC positive laminar keratinocytes. Equine Veterinary Journal. 36: 248-54. PMID 15147133  0.317
2004 Coric T, Hernandez N, Alvarez de la Rosa D, Shao D, Wang T, Canessa CM. Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G663-70. PMID 14630642 DOI: 10.1152/ajpgi.00364.2003  0.771
2003 Coric T, Zhang P, Todorovic N, Canessa CM. The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1. The Journal of Biological Chemistry. 278: 45240-7. PMID 12947112 DOI: 10.1074/jbc.M304441200  0.334
2003 Alvarez de la Rosa D, Coric T, Todorovic N, Shao D, Wang T, Canessa CM. Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney. The Journal of Physiology. 551: 455-66. PMID 12816971 DOI: 10.1113/jphysiol.2003.042903  0.793
2003 Alvarez de la Rosa D, Krueger SR, Kolar A, Shao D, Fitzsimonds RM, Canessa CM. Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system. The Journal of Physiology. 546: 77-87. PMID 12509480 DOI: 10.1113/jphysiol.2002.030692  0.743
2003 Alvarez de la Rosa D, Canessa CM. Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells. American Journal of Physiology. Cell Physiology. 284: C404-14. PMID 12388075 DOI: 10.1152/ajpcell.00398.2002  0.765
2002 Zhang P, Canessa CM. Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes. The Journal of General Physiology. 120: 553-66. PMID 12356856 DOI: 10.1085/jgp.20028574  0.417
2002 Alvarez de la Rosa D, Li H, Canessa CM. Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells. The Journal of General Physiology. 119: 427-42. PMID 11981022 DOI: 10.1085/jgp.20028559  0.795
2002 Alvarez de la Rosa D, Zhang P, Shao D, White F, Canessa CM. Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. 99: 2326-31. PMID 11842212 DOI: 10.1073/Pnas.042688199  0.771
2001 Zhang P, Canessa CM. Single-channel properties of recombinant acid-sensitive ion channels formed by the subunits ASIC2 and ASIC3 from dorsal root ganglion neurons expressed in Xenopus oocytes. The Journal of General Physiology. 117: 563-72. PMID 11382806 DOI: 10.1085/jgp.117.6.563  0.379
2000 Gupta SS, Canessa CM. Heterologous expression of a mammalian epithelial sodium channel in yeast. Febs Letters. 481: 77-80. PMID 10984619 DOI: 10.1016/S0014-5793(00)01977-3  0.315
2000 Alvarez de la Rosa D, Canessa CM, Fyfe GK, Zhang P. Structure and regulation of amiloride-sensitive sodium channels. Annual Review of Physiology. 62: 573-94. PMID 10845103 DOI: 10.1146/annurev.physiol.62.1.573  0.775
1999 Alvarez de la Rosa D, Zhang P, Náray-Fejes-Tóth A, Fejes-Tóth G, Canessa CM. The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes. The Journal of Biological Chemistry. 274: 37834-9. PMID 10608847 DOI: 10.1074/jbc.274.53.37834  0.786
1999 Fyfe GK, Zhang P, Canessa CM. The second hydrophobic domain contributes to the kinetic properties of epithelial sodium channels. The Journal of Biological Chemistry. 274: 36415-21. PMID 10593937 DOI: 10.1074/jbc.274.51.36415  0.394
1999 Zhang P, Fyfe GK, Grichtchenko II, Canessa CM. Inhibition of alphabeta epithelial sodium channels by external protons indicates that the second hydrophobic domain contains structural elements for closing the pore. Biophysical Journal. 77: 3043-51. PMID 10585926 DOI: 10.1016/S0006-3495(99)77135-3  0.383
1999 Trujillo E, Alvarez de la Rosa D, Mobasheri A, González T, Canessa CM, Martín-Vasallo P. Sodium transport systems in human chondrocytes. II. Expression of ENaC, Na+/K+/2Cl- cotransporter and Na+/H+ exchangers in healthy and arthritic chondrocytes. Histology and Histopathology. 14: 1023-31. PMID 10506918 DOI: 10.14670/Hh-14.1023  0.763
1999 Náray-Fejes-Tóth A, Canessa C, Cleaveland ES, Aldrich G, Fejes-Tóth G. sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels. The Journal of Biological Chemistry. 274: 16973-8. PMID 10358046 DOI: 10.1074/Jbc.274.24.16973  0.464
1999 Zhang P, Fyfe GK, Grichtchenko II, Canessa CM. Inhibition of αβ epithelial sodium channels by external protons indicates that the second hydrophobic domain contains structural elements for closing the pore Biophysical Journal. 77: 3043-3051.  0.308
1998 Valentijn JA, Fyfe GK, Canessa CM. Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes. The Journal of Biological Chemistry. 273: 30344-51. PMID 9804797 DOI: 10.1074/jbc.273.46.30344  0.47
1998 Fyfe GK, Canessa CM. Subunit composition determines the single channel kinetics of the epithelial sodium channel. The Journal of General Physiology. 112: 423-32. PMID 9758861 DOI: 10.1085/jgp.112.4.423  0.391
1998 Fyfe GK, Quinn A, Canessa CM. Structure and function of the Mec-ENaC family of ion channels. Seminars in Nephrology. 18: 138-51. PMID 9541269  0.38
1998 Shimkets RA, Lifton R, Canessa CM. In vivo phosphorylation of the epithelial sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 95: 3301-5. PMID 9501257 DOI: 10.1073/Pnas.95.6.3301  0.37
1997 Shimkets RA, Lifton RP, Canessa CM. The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis. The Journal of Biological Chemistry. 272: 25537-41. PMID 9325269 DOI: 10.1074/Jbc.272.41.25537  0.425
1997 McNicholas CM, Canessa CM. Diversity of channels generated by different combinations of epithelial sodium channel subunits. The Journal of General Physiology. 109: 681-92. PMID 9222895 DOI: 10.1085/jgp.109.6.681  0.358
1997 Farman N, Talbot CR, Boucher R, Fay M, Canessa C, Rossier B, Bonvalet JP. Noncoordinated expression of alpha-, beta-, and gamma-subunit mRNAs of epithelial Na+ channel along rat respiratory tract. The American Journal of Physiology. 272: C131-41. PMID 9038819 DOI: 10.1152/ajpcell.1997.272.1.C131  0.427
1996 Canessa CM. What is new about the structure of the epithelial Na+ channel? News in Physiological Sciences. 11: 195-201.  0.369
1995 Letz B, Ackermann A, Canessa CM, Rossier BC, Korbmacher C. Amiloride-sensitive sodium channels in confluent M-1 mouse cortical collecting duct cells. The Journal of Membrane Biology. 148: 127-41. PMID 8606362 DOI: 10.1007/BF00207269  0.377
1995 Canessa CM, Horisberger JD, Schild L, Rossier BC. Expression cloning of the epithelial sodium channel. Kidney International. 48: 950-5. PMID 8569104  0.421
1995 Schild L, Canessa CM, Shimkets RA, Gautschi I, Lifton RP, Rossier BC. A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system. Proceedings of the National Academy of Sciences of the United States of America. 92: 5699-703. PMID 7777572 DOI: 10.1073/Pnas.92.12.5699  0.458
1995 Burch LH, Talbot CR, Knowles MR, Canessa CM, Rossier BC, Boucher RC. Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways. The American Journal of Physiology. 269: C511-8. PMID 7653534 DOI: 10.1152/Ajpcell.1995.269.2.C511  0.395
1995 Puoti A, May A, Canessa CM, Horisberger JD, Schild L, Rossier BC. The highly selective low-conductance epithelial Na channel of Xenopus laevis A6 kidney cells. The American Journal of Physiology. 269: C188-97. PMID 7631745  0.464
1995 Antolovic R, Schoner W, Geering K, Canessa C, Rossier BC, Horisberger JD. Labeling of a cysteine in the cardiotonic glycoside binding site by the steroid derivative HDMA. Febs Letters. 368: 169-72. PMID 7615075 DOI: 10.1016/0014-5793(95)00637-O  0.324
1995 Fuller CM, Awayda MS, Arrate MP, Bradford AL, Morris RG, Canessa CM, Rossier BC, Benos DJ. Cloning of a bovine renal epithelial Na+ channel subunit. The American Journal of Physiology. 269: C641-54. PMID 7573394 DOI: 10.1152/Ajpcell.1995.269.3.C641  0.443
1995 Hansson JH, Nelson-Williams C, Suzuki H, Schild L, Shimkets R, Lu Y, Canessa C, Iwasaki T, Rossier B, Lifton RP. Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome. Nature Genetics. 11: 76-82. PMID 7550319 DOI: 10.1038/Ng0995-76  0.471
1995 Stutts MJ, Canessa CM, Olsen JC, Hamrick M, Cohn JA, Rossier BC, Boucher RC. CFTR as a cAMP-dependent regulator of sodium channels. Science (New York, N.Y.). 269: 847-50. PMID 7543698 DOI: 10.1126/Science.7543698  0.519
1994 Canessa CM, Schild L, Buell G, Thorens B, Gautschi I, Horisberger JD, Rossier BC. Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature. 367: 463-7. PMID 8107805 DOI: 10.1038/367463a0  0.475
1994 Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, Gill JR, Ulick S, Milora RV, Findling JW, Canessa CM, Rossier BC, Lifton RP. Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel Cell. 79: 407-414. PMID 7954808 DOI: 10.1016/0092-8674(94)90250-X  0.346
1994 Rotin D, Bar-Sagi D, O'Brodovich H, Merilainen J, Lehto VP, Canessa CM, Rossier BC, Downey GP. An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane. The Embo Journal. 13: 4440-50. PMID 7925286 DOI: 10.1002/J.1460-2075.1994.Tb06766.X  0.398
1994 Canessa CM, Merillat AM, Rossier BC. Membrane topology of the epithelial sodium channel in intact cells. The American Journal of Physiology. 267: C1682-90. PMID 7810611  0.318
1994 Duc C, Farman N, Canessa CM, Bonvalet JP, Rossier BC. Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry. The Journal of Cell Biology. 127: 1907-21. PMID 7806569 DOI: 10.1083/jcb.127.6.1907  0.465
1994 Rossier BC, Canessa CM, Schild L, Horisberger JD. Epithelial sodium channels. Current Opinion in Nephrology and Hypertension. 3: 487-96. PMID 7804746  0.429
1994 Horisberger JD, Puoti A, Canessa C, Rossier BC. The amiloride receptor. The Clinical Investigator. 72: 695-7. PMID 7531520 DOI: 10.1007/BF00212992  0.493
1994 Canessa C, Jaisser F, Horisberger JD, Rossier BC. Structure-function relationship of Na,K-ATPase: The digitalis receptor Current Topics in Membranes. 41: 71-85. DOI: 10.1016/S0070-2161(08)60454-2  0.339
1993 Canessa CM, Horisberger JD, Rossier BC. Epithelial sodium channel related to proteins involved in neurodegeneration. Nature. 361: 467-70. PMID 8381523 DOI: 10.1038/361467a0  0.43
1993 Horisberger JD, Canessa C, Rossier BC. The epithelial sodium channel: Recent developments Cellular Physiology and Biochemistry. 3: 283-294. DOI: 10.1159/000154694  0.579
1992 Canessa CM, Schafer JA. AVP stimulates Na+ transport in primary cultures of rabbit cortical collecting duct cells. The American Journal of Physiology. 262: F454-61. PMID 1558162  0.311
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