| Year |
Citation |
Score |
| 2023 |
McDonald B, Chick BY, Hargreaves DC, Kaech SM. Early Chromatin Remodeling Events in Acutely Stimulated CD8 T Cells. The Yale Journal of Biology and Medicine. 96: 467-473. PMID 38161581 DOI: 10.59249/AXGU7370 |
0.516 |
|
| 2023 |
Giles JR, Globig AM, Kaech SM, Wherry EJ. CD8 T cells in the cancer-immunity cycle. Immunity. 56: 2231-2253. PMID 37820583 DOI: 10.1016/j.immuni.2023.09.005 |
0.672 |
|
| 2023 |
Globig AM, Zhao S, Roginsky J, Maltez VI, Guiza J, Avina-Ochoa N, Heeg M, Araujo Hoffmann F, Chaudhary O, Wang J, Senturk G, Chen D, O'Connor C, Pfaff S, Germain RN, ... ... Kaech SM, et al. The β-adrenergic receptor links sympathetic nerves to T cell exhaustion. Nature. PMID 37731001 DOI: 10.1038/s41586-023-06568-6 |
0.578 |
|
| 2023 |
Mittra S, Harding SM, Kaech SM. Memory T Cells in the Immunoprevention of Cancer: A Switch from Therapeutic to Prophylactic Approaches. Journal of Immunology (Baltimore, Md. : 1950). 211: 907-916. PMID 37669503 DOI: 10.4049/jimmunol.2300049 |
0.468 |
|
| 2023 |
Chen D, Varanasi SK, Hara T, Traina K, Sun M, McDonald B, Farsakoglu Y, Clanton J, Xu S, Garcia-Rivera L, Mann TH, Du V, Chung HK, Xu Z, Tripple V, ... ... Kaech SM, et al. CTLA-4 blockade induces CD4 T cell IFNγ-driven microglial phagocytosis and anti-tumor function in glioblastoma. Immunity. PMID 37572655 DOI: 10.1016/j.immuni.2023.07.015 |
0.539 |
|
| 2023 |
Krykbaeva I, Bridges K, Damsky W, Pizzurro GA, Alexander AF, McGeary MK, Park K, Muthusamy V, Eyles J, Luheshi N, Turner N, Weiss SA, Olino K, Kaech SM, Kluger HM, et al. Combinatorial immunotherapy with agonistic CD40 activates dendritic cells to express IL12 and overcomes PD-1 resistance. Cancer Immunology Research. PMID 37478171 DOI: 10.1158/2326-6066.CIR-22-0699 |
0.359 |
|
| 2023 |
McDonald B, Chick BY, Ahmed NS, Burns M, Ma S, Casillas E, Chen D, Mann TH, O'Connor C, Hah N, Hargreaves DC, Kaech SM. Canonical BAF complex activity shapes the enhancer landscape that licenses CD8 T cell effector and memory fates. Immunity. 56: 1303-1319.e5. PMID 37315534 DOI: 10.1016/j.immuni.2023.05.005 |
0.579 |
|
| 2023 |
McGeary MK, Damsky W, Daniels A, Song E, Micevic G, Huet-Calderwood C, Lou HJ, Paradkar S, Kaech S, Calderwood DA, Turk BE, Iwasaki A, Bosenberg MW. -loss induces type-I interferons and immune clearance of melanoma. Biorxiv : the Preprint Server For Biology. PMID 37292991 DOI: 10.1101/2023.05.23.541922 |
0.354 |
|
| 2023 |
Chung HK, Liu C, Casillas E, Chick B, Mcdonald B, Wang J, He P, Sun M, Ma S, Yang Q, Chen D, Hoffmann F, Varanasi SK, Tripple V, Hang Y, ... ... Kaech SM, et al. Multiomics atlas-assisted discovery of transcription factors enables specific cell state programming. Biorxiv : the Preprint Server For Biology. PMID 36711632 DOI: 10.1101/2023.01.03.522354 |
0.463 |
|
| 2022 |
Kasmani MY, Zander R, Chung HK, Chen Y, Khatun A, Damo M, Topchyan P, Johnson KE, Levashova D, Burns R, Lorenz UM, Tarakanova VL, Joshi NS, Kaech SM, Cui W. Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection. The Journal of Experimental Medicine. 220. PMID 36315049 DOI: 10.1084/jem.20220679 |
0.554 |
|
| 2021 |
Zhao S, Peralta RM, Avina-Ochoa N, Delgoffe GM, Kaech SM. Metabolic regulation of T cells in the tumor microenvironment by nutrient availability and diet. Seminars in Immunology. 101485. PMID 34462190 DOI: 10.1016/j.smim.2021.101485 |
0.41 |
|
| 2021 |
Qian Y, Arellano G, Ifergan I, Lin J, Snowden C, Kim T, Thomas JJ, Law C, Guan T, Balabanov RD, Kaech SM, Miller SD, Choi J. ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis. Cell Reports. 36: 109602. PMID 34433042 DOI: 10.1016/j.celrep.2021.109602 |
0.364 |
|
| 2021 |
Mann TH, Kaech SM. Counting on You: How MHC Tetramers Revolutionized the Study of T Cell Memory and CD8 T Cell Exhaustion. Journal of Immunology (Baltimore, Md. : 1950). 207: 1225-1227. PMID 34426517 DOI: 10.4049/jimmunol.2100533 |
0.631 |
|
| 2021 |
Xu S, Chaudhary O, Rodríguez-Morales P, Sun X, Chen D, Zappasodi R, Xu Z, Pinto AFM, Williams A, Schulze I, Farsakoglu Y, Varanasi SK, Low JS, Tang W, Wang H, ... ... Kaech SM, et al. Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8 T cells in tumors. Immunity. PMID 34102100 DOI: 10.1016/j.immuni.2021.05.003 |
0.415 |
|
| 2021 |
Farsakoglu Y, McDonald B, Kaech SM. Motility Matters: How CD8 T-Cell Trafficking Influences Effector and Memory Cell Differentiation. Cold Spring Harbor Perspectives in Biology. PMID 34001529 DOI: 10.1101/cshperspect.a038075 |
0.631 |
|
| 2021 |
Van Acker HH, Ma S, Scolaro T, Kaech SM, Mazzone M. How metabolism bridles cytotoxic CD8 T cells through epigenetic modifications. Trends in Immunology. 42: 401-417. PMID 33867272 DOI: 10.1016/j.it.2021.03.006 |
0.502 |
|
| 2021 |
Chung HK, McDonald B, Kaech SM. The architectural design of CD8+ T cell responses in acute and chronic infection: Parallel structures with divergent fates. The Journal of Experimental Medicine. 218. PMID 33755719 DOI: 10.1084/jem.20201730 |
0.561 |
|
| 2020 |
DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, ... ... Kaech SM, et al. Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. Gastroenterology. PMID 32717220 DOI: 10.1053/J.Gastro.2020.07.037 |
0.354 |
|
| 2020 |
Low JS, Farsakoglu Y, Amezcua Vesely MC, Sefik E, Kelly JB, Harman CCD, Jackson R, Shyer JA, Jiang X, Cauley LS, Flavell RA, Kaech SM. Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses. The Journal of Experimental Medicine. 217. PMID 32525985 DOI: 10.1084/Jem.20192291 |
0.673 |
|
| 2020 |
Crotty S, Blish C, Cadwell K, Chi H, Goldrath A, Green D, Kaech SM, Krummel M, Pepper M, Rothlin CV, Wherry EJ. Reinvigorating NIH Grant Peer Review. Immunity. 52: 1-3. PMID 31940266 DOI: 10.1016/J.Immuni.2019.12.016 |
0.424 |
|
| 2019 |
Varanasi SK, Ma S, Kaech SM. T Cell Metabolism in a State of Flux. Immunity. 51: 783-785. PMID 31747577 DOI: 10.1016/J.Immuni.2019.10.012 |
0.518 |
|
| 2019 |
Harel M, Ortenberg R, Varanasi SK, Mangalhara KC, Mardamshina M, Markovits E, Baruch EN, Tripple V, Arama-Chayoth M, Greenberg E, Shenoy A, Ayasun R, Knafo N, Xu S, Anafi L, ... ... Kaech SM, et al. Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence. Cell. PMID 31495571 DOI: 10.1016/J.Cell.2019.08.012 |
0.333 |
|
| 2019 |
Mann TH, Kaech SM. Tick-TOX, it's time for T cell exhaustion. Nature Immunology. 20: 1092-1094. PMID 31427776 DOI: 10.1038/S41590-019-0478-Y |
0.621 |
|
| 2019 |
Gaffney SG, Perry EB, Chen PM, Greenstein A, Kaech SM, Townsend JP. The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment. Oncotarget. 10: 4532-4545. PMID 31360302 DOI: 10.18632/Oncotarget.27027 |
0.332 |
|
| 2019 |
Myers LM, Tal MC, Torrez Dulgeroff LB, Carmody AB, Messer RJ, Gulati G, Yiu YY, Staron MM, Angel CL, Sinha R, Markovic M, Pham EA, Fram B, Ahmed A, Newman AM, ... ... Kaech SM, et al. A functional subset of CD8 T cells during chronic exhaustion is defined by SIRPα expression. Nature Communications. 10: 794. PMID 30770827 DOI: 10.1038/S41467-019-08637-9 |
0.627 |
|
| 2018 |
Fan MY, Low JS, Tanimine N, Finn KK, Priyadharshini B, Germana SK, Kaech SM, Turka LA. Differential Roles of IL-2 Signaling in Developing versus Mature Tregs. Cell Reports. 25: 1204-1213.e4. PMID 30380412 DOI: 10.1016/J.Celrep.2018.10.002 |
0.402 |
|
| 2018 |
Kaech SM. T-bet in Tfh cells: Now you see me, now you don't. The Journal of Experimental Medicine. PMID 30337467 DOI: 10.1084/Jem.20181878 |
0.546 |
|
| 2018 |
Gettinger SN, Choi J, Mani N, Sanmamed MF, Datar I, Sowell R, Du VY, Kaftan E, Goldberg S, Dong W, Zelterman D, Politi K, Kavathas P, Kaech S, Yu X, et al. A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers. Nature Communications. 9: 3196. PMID 30097571 DOI: 10.1038/S41467-018-05032-8 |
0.494 |
|
| 2018 |
Arojo OA, Ouyang X, Liu D, Meng T, Kaech SM, Pereira JP, Su B. Active mTORC2 Signaling in Naive T Cells Suppresses Bone Marrow Homing by Inhibiting CXCR4 Expression. Journal of Immunology (Baltimore, Md. : 1950). PMID 29934471 DOI: 10.4049/Jimmunol.1800529 |
0.532 |
|
| 2018 |
Pereira FV, Melo ACL, Low JS, de Castro ÍA, Braga TT, Almeida DC, Batista de Lima AGU, Hiyane MI, Correa-Costa M, Andrade-Oliveira V, Origassa CST, Pereira RM, Kaech SM, Rodrigues EG, Câmara NOS. Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response. Oncotarget. 9: 25808-25825. PMID 29899823 DOI: 10.18632/Oncotarget.25380 |
0.488 |
|
| 2018 |
Herndler-Brandstetter D, Ishigame H, Shinnakasu R, Plajer V, Stecher C, Zhao J, Lietzenmayer M, Kroehling L, Takumi A, Kometani K, Inoue T, Kluger Y, Kaech SM, Kurosaki T, Okada T, et al. KLRG1 Effector CD8 T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity. Immunity. 48: 716-729.e8. PMID 29625895 DOI: 10.1016/J.Immuni.2018.03.015 |
0.675 |
|
| 2018 |
Guan T, Dominguez CX, Amezquita RA, Laidlaw BJ, Cheng J, Henao-Mejia J, Williams A, Flavell RA, Lu J, Kaech SM. ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8T cell fates. The Journal of Experimental Medicine. PMID 29449309 DOI: 10.1084/Jem.20171352 |
0.778 |
|
| 2018 |
Weinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J. Correction: STAT4 and T-bet control follicular helper T cell development in viral infections. The Journal of Experimental Medicine. PMID 29440270 DOI: 10.1084/Jem.2017045702062018C |
0.557 |
|
| 2018 |
Perry CJ, Muñoz-Rojas AR, Meeth KM, Kellman LN, Amezquita RA, Thakral D, Du VY, Wang JX, Damsky W, Kuhlmann AL, Sher JW, Bosenberg M, Miller-Jensen K, Kaech SM. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. The Journal of Experimental Medicine. PMID 29436395 DOI: 10.1084/Jem.20171435 |
0.404 |
|
| 2018 |
Low JS, Kaech SM. Trials and Tribble-ations of tissue TRM cells. Nature Immunology. PMID 29348504 DOI: 10.1038/S41590-017-0031-9 |
0.53 |
|
| 2018 |
Weinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J. STAT4 and T-bet control follicular helper T cell development in viral infections. The Journal of Experimental Medicine. 215: 337-355. PMID 29212666 DOI: 10.1084/Jem.20170457 |
0.548 |
|
| 2018 |
Hastings K, Gettinger S, Jungmin C, Truini A, Datar I, Sowell R, Wurtz A, Dong W, Cai G, Melnick MA, Schlessinger J, Goldberg S, Chiang A, Melero I, Agorreta J, ... ... Kaech S, et al. Abstract A09: Impaired HLA Class I antigen processing and presentation as a mechanism of acquired Rrsistance to immune checkpoint inhibitors in lung cancer Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-A09 |
0.309 |
|
| 2017 |
Laidlaw BJ, Lu Y, Amezquita RA, Weinstein JS, Vander Heiden JA, Gupta NT, Kleinstein SH, Kaech SM, Craft J. Interleukin-10 from CD4(+) follicular regulatory T cells promotes the germinal center response. Science Immunology. 2. PMID 29054998 DOI: 10.1126/Sciimmunol.Aan4767 |
0.544 |
|
| 2017 |
Yeon SM, Halim L, Chandele A, Perry CJ, Kim SH, Kim SU, Byun Y, Yuk SH, Kaech SM, Jung YW. IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways. Scientific Reports. 7: 11155. PMID 28894184 DOI: 10.1038/S41598-017-11492-7 |
0.619 |
|
| 2017 |
Shin HM, Kapoor VN, Kim G, Li P, Kim HR, Suresh M, Kaech SM, Wherry EJ, Selin LK, Leonard WJ, Welsh RM, Berg LJ. Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory. Plos Pathogens. 13: e1006544. PMID 28827827 DOI: 10.1371/Journal.Ppat.1006544 |
0.776 |
|
| 2017 |
Roberts NA, Adams BD, McCarthy NI, Tooze RM, Parnell SM, Anderson G, Kaech SM, Horsley V. Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 28701508 DOI: 10.4049/Jimmunol.1600941 |
0.493 |
|
| 2017 |
Buck MD, Sowell RT, Kaech SM, Pearce EL. Metabolic Instruction of Immunity. Cell. 169: 570-586. PMID 28475890 DOI: 10.1016/J.Cell.2017.04.004 |
0.358 |
|
| 2017 |
Ho PC, Kaech SM. Reenergizing T cell anti-tumor immunity by harnessing immunometabolic checkpoints and machineries. Current Opinion in Immunology. 46: 38-44. PMID 28458087 DOI: 10.1016/J.Coi.2017.04.003 |
0.52 |
|
| 2017 |
Gray SM, Amezquita RA, Guan T, Kleinstein SH, Kaech SM. Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8(+) T Cell Terminal Differentiation and Loss of Multipotency. Immunity. PMID 28410989 DOI: 10.1016/J.Immuni.2017.03.012 |
0.642 |
|
| 2017 |
Wang J, Perry CJ, Meeth K, Thakral D, Damsky W, Micevic G, Kaech S, Blenman K, Bosenberg M. UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 Mouse Melanoma Model. Pigment Cell & Melanoma Research. PMID 28379630 DOI: 10.1111/Pcmr.12591 |
0.42 |
|
| 2017 |
Amezquita RA, Kaech SM. Immunology: The chronicles of T-cell exhaustion. Nature. PMID 28225757 DOI: 10.1038/Nature21508 |
0.566 |
|
| 2016 |
Poholek AC, Jankovic D, Villarino AV, Petermann F, Hettinga A, Shouval DS, Snapper SB, Kaech SM, Brooks SR, Vahedi G, Sher A, Kanno Y, O'Shea JJ. IL-10 induces a STAT3-dependent autoregulatory loop in TH2 cells that promotes Blimp-1 restriction of cell expansion via antagonism of STAT5 target genes. Science Immunology. 1. PMID 28713870 DOI: 10.1126/Sciimmunol.Aaf8612 |
0.549 |
|
| 2016 |
Adams NM, O'Sullivan TE, Geary CD, Karo JM, Amezquita RA, Joshi NS, Kaech SM, Sun JC. NK Cell Responses Redefine Immunological Memory. Journal of Immunology (Baltimore, Md. : 1950). 197: 2963-2970. PMID 27824591 DOI: 10.4049/Jimmunol.1600973 |
0.509 |
|
| 2016 |
Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV. ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. The Journal of Clinical Investigation. PMID 27617863 DOI: 10.1172/Jci85329 |
0.524 |
|
| 2016 |
Sowell RT, Kaech SM. Probing the Diversity of T Cell Dysfunction in Cancer. Cell. 166: 1362-4. PMID 27610560 DOI: 10.1016/J.Cell.2016.08.058 |
0.51 |
|
| 2016 |
Kritikou JS, Dahlberg CI, Baptista MA, Wagner AK, Banerjee PP, Gwalani LA, Poli C, Panda SK, Kärre K, Kaech SM, Wermeling F, Andersson J, Orange JS, Brauner H, Westerberg LS. IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo. Scientific Reports. 6: 30636. PMID 27477778 DOI: 10.1038/Srep30636 |
0.451 |
|
| 2016 |
Jung YW, Kim HG, Perry CJ, Kaech SM. CCR7 expression alters memory CD8 T-cell homeostasis by regulating occupancy in IL-7- and IL-15-dependent niches. Proceedings of the National Academy of Sciences of the United States of America. PMID 27385825 DOI: 10.1073/Pnas.1602899113 |
0.665 |
|
| 2016 |
Garyu JW, Uduman M, Stewart A, Rui J, Deng S, Shenson J, Staron MM, Kaech SM, Kleinstein SH, Herold KC. Characterization of diabetogenic CD8+ T cells: immune therapy with metabolic blockade. The Journal of Biological Chemistry. PMID 26994137 DOI: 10.1074/Jbc.M115.713362 |
0.573 |
|
| 2016 |
Xin A, Masson F, Liao Y, Preston S, Guan T, Gloury R, Olshansky M, Lin JX, Li P, Speed TP, Smyth GK, Ernst M, Leonard WJ, Pellegrini M, Kaech SM, et al. A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet. Nature Immunology. PMID 26950239 DOI: 10.1038/Ni.3410 |
0.641 |
|
| 2016 |
Laidlaw BJ, Craft JE, Kaech SM. The multifaceted role of CD4(+) T cells in CD8(+) T cell memory. Nature Reviews. Immunology. 16: 102-11. PMID 26781939 DOI: 10.1038/Nri.2015.10 |
0.714 |
|
| 2016 |
Cui G, Ho P, Amezquita R, Kaech SM. Abstract IA03: Anti-tumor T cells: You are what you eat Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-Ia03 |
0.53 |
|
| 2016 |
Cui G, Kaech S. Abstract B063: Unsaturated fatty acids cause CD8+ T cell exhaustion in melanoma Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B063 |
0.521 |
|
| 2016 |
Ayeni D, Ho P, Perry C, Kaech S, Politi K. Abstract A083: Modulation of the immune system as a strategy to treat EGFR mutant lung adenocarcinoma Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A083 |
0.37 |
|
| 2016 |
Wang J, Meeth K, Perry C, Ventura A, Kaech S, Edelson R, Bosenberg M. 616 UV-induced somatic mutations elicit a functional T cell response and tumor regression in BRAF V600E , CDKN2A -/- , PTEN -/- melanoma model Journal of Investigative Dermatology. 136: S109. DOI: 10.1016/J.Jid.2016.02.656 |
0.402 |
|
| 2015 |
Dominguez CX, Amezquita RA, Guan T, Marshall HD, Joshi NS, Kleinstein SH, Kaech SM. The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection. The Journal of Experimental Medicine. PMID 26503446 DOI: 10.1084/Jem.20150186 |
0.833 |
|
| 2015 |
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J. The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. PMID 26410627 DOI: 10.1016/J.Immuni.2015.08.017 |
0.679 |
|
| 2015 |
Ho PC, Bihuniak JD, Macintyre AN, Staron M, Liu X, Amezquita R, Tsui YC, Cui G, Micevic G, Perales JC, Kleinstein SH, Abel ED, Insogna KL, Feske S, Locasale JW, ... ... Kaech SM, et al. Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses. Cell. PMID 26321681 DOI: 10.1016/J.Cell.2015.08.012 |
0.539 |
|
| 2015 |
Laidlaw BJ, Cui W, Amezquita RA, Gray SM, Guan T, Lu Y, Kobayashi Y, Flavell RA, Kleinstein SH, Craft J, Kaech SM. Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells. Nature Immunology. PMID 26147684 DOI: 10.1038/Ni.3224 |
0.675 |
|
| 2015 |
Cui G, Staron MM, Gray SM, Ho PC, Amezquita RA, Wu J, Kaech SM. IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity. Cell. 161: 750-61. PMID 25957683 DOI: 10.1016/J.Cell.2015.03.021 |
0.645 |
|
| 2015 |
Chen JH, Perry CJ, Tsui YC, Staron MM, Parish IA, Dominguez CX, Rosenberg DW, Kaech SM. Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection. Nature Medicine. 21: 327-34. PMID 25799228 DOI: 10.1038/Nm.3831 |
0.745 |
|
| 2015 |
West AP, Khoury-Hanold W, Staron M, Tal MC, Pineda CM, Lang SM, Bestwick M, Duguay BA, Raimundo N, MacDuff DA, Kaech SM, Smiley JR, Means RE, Iwasaki A, Shadel GS. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 520: 553-7. PMID 25642965 DOI: 10.1038/Nature14156 |
0.303 |
|
| 2015 |
Hu Y, Lee YT, Kaech SM, Garvy B, Cauley LS. Smad4 promotes differentiation of effector and circulating memory CD8 T cells but is dispensable for tissue-resident memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 2407-14. PMID 25637015 DOI: 10.4049/Jimmunol.1402369 |
0.674 |
|
| 2015 |
Marshall HD, Ray JP, Laidlaw BJ, Zhang N, Gawande D, Staron MM, Craft J, Kaech SM. The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa. Elife. 4: e04851. PMID 25569154 DOI: 10.7554/Elife.04851 |
0.577 |
|
| 2015 |
Mohanty S, Joshi SR, Ueda I, Wilson J, Blevins TP, Siconolfi B, Meng H, Devine L, Raddassi K, Tsang S, Belshe RB, Hafler DA, Kaech SM, Kleinstein SH, Trentalange M, et al. Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. The Journal of Infectious Diseases. 211: 1174-84. PMID 25367297 DOI: 10.1093/Infdis/Jiu573 |
0.31 |
|
| 2014 |
Staron MM, Gray SM, Marshall HD, Parish IA, Chen JH, Perry CJ, Cui G, Li MO, Kaech SM. The transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8(+) T cells during chronic infection. Immunity. 41: 802-14. PMID 25464856 DOI: 10.1016/J.Immuni.2014.10.013 |
0.46 |
|
| 2014 |
Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF, ten Brinke A, Willemsen AM, van Kampen AH, Kaech SM, Blander JM, et al. A central role for Notch in effector CD8(+) T cell differentiation. Nature Immunology. 15: 1143-51. PMID 25344724 DOI: 10.1038/Ni.3027 |
0.853 |
|
| 2014 |
Laidlaw BJ, Zhang N, Marshall HD, Staron MM, Guan T, Hu Y, Cauley LS, Craft J, Kaech SM. CD4+ T cell help guides formation of CD103+ lung-resident memory CD8+ T cells during influenza viral infection. Immunity. 41: 633-45. PMID 25308332 DOI: 10.1016/J.Immuni.2014.09.007 |
0.623 |
|
| 2014 |
Shaw PJ, Weidinger C, Vaeth M, Luethy K, Kaech SM, Feske S. CD4⺠and CD8⺠T cell-dependent antiviral immunity requires STIM1 and STIM2. The Journal of Clinical Investigation. 124: 4549-63. PMID 25157823 DOI: 10.1172/Jci76602 |
0.655 |
|
| 2014 |
Gray SM, Kaech SM, Staron MM. The interface between transcriptional and epigenetic control of effector and memory CD8⁺ T-cell differentiation. Immunological Reviews. 261: 157-68. PMID 25123283 DOI: 10.1111/Imr.12205 |
0.596 |
|
| 2014 |
Ho PC, Kaech SM. BRAF-targeted therapy alters the functions of intratumoral CD4(+) T cells to inhibit melanoma progression. Oncoimmunology. 3: e29126. PMID 25083331 DOI: 10.4161/Onci.29126 |
0.589 |
|
| 2014 |
Gate D, Danielpour M, Rodriguez J, Kim GB, Levy R, Bannykh S, Breunig JJ, Kaech SM, Flavell RA, Town T. T-cell TGF-β signaling abrogation restricts medulloblastoma progression. Proceedings of the National Academy of Sciences of the United States of America. 111: E3458-66. PMID 25082897 DOI: 10.1073/Pnas.1412489111 |
0.596 |
|
| 2014 |
Marshall HD, Kaech SM. Regulating the diverse outcomes of interferon's interference. Trends in Immunology. 35: 353-4. PMID 25052591 DOI: 10.1016/J.It.2014.07.002 |
0.567 |
|
| 2014 |
Parish IA, Marshall HD, Staron MM, Lang PA, Brüstle A, Chen JH, Cui W, Tsui YC, Perry C, Laidlaw BJ, Ohashi PS, Weaver CT, Kaech SM. Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1. The Journal of Clinical Investigation. 124: 3455-68. PMID 25003188 DOI: 10.1172/Jci66108 |
0.47 |
|
| 2014 |
Ho PC, Meeth KM, Tsui YC, Srivastava B, Bosenberg MW, Kaech SM. Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ. Cancer Research. 74: 3205-17. PMID 24736544 DOI: 10.1158/0008-5472.Can-13-3461 |
0.43 |
|
| 2014 |
Cui W, Joshi NS, Liu Y, Meng H, Kleinstein SH, Kaech SM. TLR4 ligands lipopolysaccharide and monophosphoryl lipid a differentially regulate effector and memory CD8+ T Cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 192: 4221-32. PMID 24659688 DOI: 10.4049/Jimmunol.1302569 |
0.658 |
|
| 2014 |
Ray JP, Marshall HD, Laidlaw BJ, Staron MM, Kaech SM, Craft J. Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells. Immunity. 40: 367-77. PMID 24631156 DOI: 10.1016/J.Immuni.2014.02.005 |
0.645 |
|
| 2014 |
Kaech SM. Celebrating diversity in memory T cells. Journal of Immunology (Baltimore, Md. : 1950). 192: 837-9. PMID 24443505 DOI: 10.4049/Jimmunol.1303268 |
0.512 |
|
| 2013 |
Slütter B, Pewe LL, Kaech SM, Harty JT. Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus. Immunity. 39: 939-48. PMID 24238342 DOI: 10.1016/J.Immuni.2013.09.013 |
0.665 |
|
| 2013 |
Shin HM, Kapoor VN, Guan T, Kaech SM, Welsh RM, Berg LJ. Epigenetic modifications induced by Blimp-1 Regulate CD8⺠T cell memory progression during acute virus infection. Immunity. 39: 661-75. PMID 24120360 DOI: 10.1016/J.Immuni.2013.08.032 |
0.626 |
|
| 2013 |
Marshall HD, Kaech SM. Generating CD8 T cell heterogeneity: attack of the clones. Immunity. 39: 203-5. PMID 23973217 DOI: 10.1016/J.Immuni.2013.08.008 |
0.641 |
|
| 2013 |
Zhao Y, Zhao H, Sun Y, Hao J, Qi X, Zhou X, Wu Z, Wang P, Kaech SM, Weaver CT, Flavell RA, Zhao L, Yao Z, Yin Z. IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism. Journal of Leukocyte Biology. 94: 1103-12. PMID 23772040 DOI: 10.1189/Jlb.0213064 |
0.56 |
|
| 2013 |
Henao-Mejia J, Williams A, Goff LA, Staron M, Licona-Limón P, Kaech SM, Nakayama M, Rinn JL, Flavell RA. The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. Immunity. 38: 984-97. PMID 23623381 DOI: 10.1016/J.Immuni.2013.02.021 |
0.327 |
|
| 2013 |
D'Souza AD, Parish IA, Krause DS, Kaech SM, Shadel GS. Reducing mitochondrial ROS improves disease-related pathology in a mouse model of ataxia-telangiectasia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 42-8. PMID 23011031 DOI: 10.1038/Mt.2012.203 |
0.454 |
|
| 2012 |
Kaech SM, Cui W. Transcriptional control of effector and memory CD8+ T cell differentiation. Nature Reviews. Immunology. 12: 749-61. PMID 23080391 DOI: 10.1038/Nri3307 |
0.675 |
|
| 2012 |
Demento SL, Cui W, Criscione JM, Stern E, Tulipan J, Kaech SM, Fahmy TM. Role of sustained antigen release from nanoparticle vaccines in shaping the T cell memory phenotype. Biomaterials. 33: 4957-64. PMID 22484047 DOI: 10.1016/J.Biomaterials.2012.03.041 |
0.429 |
|
| 2012 |
Lang PA, Lang KS, Xu HC, Grusdat M, Parish IA, Recher M, Elford AR, Dhanji S, Shaabani N, Tran CW, Dissanayake D, Rahbar R, Ghazarian M, Brüstle A, Fine J, ... ... Kaech SM, et al. Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity. Proceedings of the National Academy of Sciences of the United States of America. 109: 1210-5. PMID 22167808 DOI: 10.1073/Pnas.1118834109 |
0.574 |
|
| 2011 |
Cui W, Liu Y, Weinstein JS, Craft J, Kaech SM. An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells. Immunity. 35: 792-805. PMID 22118527 DOI: 10.1016/J.Immuni.2011.09.017 |
0.676 |
|
| 2011 |
Marshall HD, Chandele A, Jung YW, Meng H, Poholek AC, Parish IA, Rutishauser R, Cui W, Kleinstein SH, Craft J, Kaech SM. Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection. Immunity. 35: 633-46. PMID 22018471 DOI: 10.1016/J.Immuni.2011.08.016 |
0.856 |
|
| 2011 |
Joshi NS, Cui W, Dominguez CX, Chen JH, Hand TW, Kaech SM. Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 4068-76. PMID 21930973 DOI: 10.4049/Jimmunol.1002145 |
0.874 |
|
| 2011 |
Li N, Matte-Martone C, Zheng H, Cui W, Venkatesan S, Tan HS, McNiff J, Demetris AJ, Roopenian D, Kaech S, Shlomchik WD. Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution. Blood. 118: 5965-76. PMID 21917752 DOI: 10.1182/Blood-2011-07-367011 |
0.555 |
|
| 2011 |
D'Souza AD, Parish IA, McKay SE, Kaech SM, Shadel GS. Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling. The American Journal of Pathology. 178: 2740-51. PMID 21641396 DOI: 10.1016/J.Ajpath.2011.02.022 |
0.669 |
|
| 2011 |
Parish IA, Kaech SM. IL-7 knocks the socs off chronic viral infection. Cell. 144: 467-8. PMID 21335230 DOI: 10.1016/J.Cell.2011.01.038 |
0.339 |
|
| 2010 |
Jung YW, Rutishauser RL, Joshi NS, Haberman AM, Kaech SM. Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection. Journal of Immunology (Baltimore, Md. : 1950). 185: 5315-25. PMID 20921525 DOI: 10.4049/Jimmunol.1001948 |
0.852 |
|
| 2010 |
Jung YW, Kaech SM. Like parent, like child: inheritance of effector CD8+ T cell traits. Immunity. 33: 296-8. PMID 20870171 DOI: 10.1016/J.Immuni.2010.09.005 |
0.542 |
|
| 2010 |
Hand TW, Cui W, Jung YW, Sefik E, Joshi NS, Chandele A, Liu Y, Kaech SM. Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival. Proceedings of the National Academy of Sciences of the United States of America. 107: 16601-6. PMID 20823247 DOI: 10.1073/Pnas.1003457107 |
0.822 |
|
| 2010 |
Demento SL, Bonafé N, Cui W, Kaech SM, Caplan MJ, Fikrig E, Ledizet M, Fahmy TM. TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 185: 2989-97. PMID 20660705 DOI: 10.4049/Jimmunol.1000768 |
0.333 |
|
| 2010 |
Cui W, Kaech SM. Generation of effector CD8+ T cells and their conversion to memory T cells. Immunological Reviews. 236: 151-66. PMID 20636815 DOI: 10.1111/J.1600-065X.2010.00926.X |
0.672 |
|
| 2010 |
Rutishauser RL, Kaech SM. Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation. Immunological Reviews. 235: 219-33. PMID 20536566 DOI: 10.1111/J.0105-2896.2010.00901.X |
0.846 |
|
| 2010 |
Poholek AC, Hansen K, Hernandez SG, Eto D, Chandele A, Weinstein JS, Dong X, Odegard JM, Kaech SM, Dent AL, Crotty S, Craft J. In vivo regulation of Bcl6 and T follicular helper cell development. Journal of Immunology (Baltimore, Md. : 1950). 185: 313-26. PMID 20519643 DOI: 10.4049/Jimmunol.0904023 |
0.558 |
|
| 2010 |
Hinson ER, Joshi NS, Chen JH, Rahner C, Jung YW, Wang X, Kaech SM, Cresswell P. Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection Journal of Immunology. 184: 5723-5731. PMID 20410488 DOI: 10.4049/Jimmunol.0903752 |
0.445 |
|
| 2009 |
Rutishauser RL, Martins GA, Kalachikov S, Chandele A, Parish IA, Meffre E, Jacob J, Calame K, Kaech SM. Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity. 31: 296-308. PMID 19664941 DOI: 10.1016/J.Immuni.2009.05.014 |
0.855 |
|
| 2009 |
Parish IA, Kaech SM. Diversity in CD8(+) T cell differentiation. Current Opinion in Immunology. 21: 291-7. PMID 19497720 DOI: 10.1016/J.Coi.2009.05.008 |
0.663 |
|
| 2009 |
Whitmire JK, Asano MS, Kaech SM, Sarkar S, Hannum LG, Shlomchik MJ, Ahmed R. Requirement of B cells for generating CD4+ T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 182: 1868-76. PMID 19201839 DOI: 10.4049/Jimmunol.0802501 |
0.726 |
|
| 2009 |
Cui W, Joshi NS, Jiang A, Kaech SM. Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation. Vaccine. 27: 2177-87. PMID 19201385 DOI: 10.1016/J.Vaccine.2009.01.088 |
0.667 |
|
| 2009 |
Hand TW, Kaech SM. Intrinsic and extrinsic control of effector T cell survival and memory T cell development. Immunologic Research. 45: 46-61. PMID 18629449 DOI: 10.1007/S12026-008-8027-Z |
0.817 |
|
| 2009 |
Hand TW, Kaech SM. Decreasing the TORC on memory CD8 T‐cell formation Immunology & Cell Biology. 87: 571-573. DOI: 10.1038/Icb.2009.72 |
0.746 |
|
| 2008 |
Rahman AH, Cui W, Larosa DF, Taylor DK, Zhang J, Goldstein DR, Wherry EJ, Kaech SM, Turka LA. MyD88 plays a critical T cell-intrinsic role in supporting CD8 T cell expansion during acute lymphocytic choriomeningitis virus infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 3804-10. PMID 18768833 DOI: 10.4049/Jimmunol.181.6.3804 |
0.753 |
|
| 2008 |
Haining WN, Ebert BL, Subrmanian A, Wherry EJ, Eichbaum Q, Evans JW, Mak R, Rivoli S, Pretz J, Angelosanto J, Smutko JS, Walker BD, Kaech SM, Ahmed R, Nadler LM, et al. Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 1859-68. PMID 18641323 DOI: 10.4049/Jimmunol.181.3.1859 |
0.787 |
|
| 2008 |
Chandele A, Joshi NS, Zhu J, Paul WE, Leonard WJ, Kaech SM. Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1. Journal of Immunology (Baltimore, Md. : 1950). 180: 5309-19. PMID 18390712 DOI: 10.4049/Jimmunol.180.8.5309 |
0.581 |
|
| 2008 |
Joshi NS, Kaech SM. Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation. Journal of Immunology (Baltimore, Md. : 1950). 180: 1309-15. PMID 18209024 DOI: 10.4049/Jimmunol.180.3.1309 |
0.685 |
|
| 2008 |
Kaech S. On Our Way to a Better Understanding of CD8 T Cell Differentiation and Memory T Cell Development. Blood. 112: sci-52-sci-52. DOI: 10.1182/Blood.V112.11.Sci-52.Sci-52 |
0.668 |
|
| 2007 |
Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, Subramaniam S, Blattman JN, Barber DL, Ahmed R. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity. 27: 670-84. PMID 17950003 DOI: 10.1016/J.Immuni.2007.09.006 |
0.852 |
|
| 2007 |
Kaech SM, Wherry EJ. Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. Immunity. 27: 393-405. PMID 17892848 DOI: 10.1016/J.Immuni.2007.08.007 |
0.768 |
|
| 2007 |
D'Souza AD, Parikh N, Kaech SM, Shadel GS. Convergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation. Mitochondrion. 7: 374-85. PMID 17890163 DOI: 10.1016/J.Mito.2007.08.001 |
0.356 |
|
| 2007 |
Joshi NS, Cui W, Chandele A, Lee HK, Urso DR, Hagman J, Gapin L, Kaech SM. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity. 27: 281-95. PMID 17723218 DOI: 10.1016/J.Immuni.2007.07.010 |
0.614 |
|
| 2007 |
Hand TW, Morre M, Kaech SM. Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection. Proceedings of the National Academy of Sciences of the United States of America. 104: 11730-5. PMID 17609371 DOI: 10.1073/Pnas.0705007104 |
0.8 |
|
| 2007 |
Wu H, Yuan M, Kaech SM, Halloran ME. A statistical analysis of memory CD8 T cell differentiation: An application of a hierarchical state space model to a short time course microarray experiment The Annals of Applied Statistics. 1: 442-458. DOI: 10.1214/07-Aoas118 |
0.598 |
|
| 2007 |
Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, Subramaniam S, Blattman JN, Barber DL, Ahmed R. Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection (DOI:10.1016/j.immuni.2007.09.006) Immunity. 27: 824. DOI: 10.1016/J.Immuni.2007.11.006 |
0.825 |
|
| 2006 |
Tesar BM, Walker WE, Unternaehrer J, Joshi NS, Chandele A, Haynes L, Kaech S, Goldstein DR. Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging. Aging Cell. 5: 473-86. PMID 17129212 DOI: 10.1111/J.1474-9726.2006.00245.X |
0.42 |
|
| 2006 |
Haining WN, Ebert B, Subramanian A, Wherry EJ, Evans J, Mak R, Rivoli S, Angelosanto J, Pretz J, Kaech S, Ahmed R, Nadler LM, Golub TR. All Memory Lymphocytes Share a Common Differentiation Program. Blood. 108: 865-865. DOI: 10.1182/Blood.V108.11.865.865 |
0.758 |
|
| 2006 |
Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, et al. Erratum: Corrigendum: Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin Nature Immunology. 7: 113-113. DOI: 10.1038/Ni0106-113 |
0.721 |
|
| 2006 |
Haining WN, Ebert B, Subramanian A, Kaech S, Ahmed R, Nadler L, Wherry EJ, Golub T. Su.66. Memory T-Cells in Mice and Humans Share a Common Molecular Program of Differentiation Regardless of Phenotype, Lineage Or Species Clinical Immunology. 119: S182-S183. DOI: 10.1016/J.Clim.2006.04.493 |
0.704 |
|
| 2006 |
Haining W, Ebert B, Subramanian A, Golub T, Kaech S, Wherry E, Nadler L. Transcriptional mapping of the anti-viral T cell response shows that impaired memory differentiation causes T cell dysfunction Biology of Blood and Marrow Transplantation. 12: 76. DOI: 10.1016/J.Bbmt.2005.11.239 |
0.606 |
|
| 2005 |
Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, et al. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nature Immunology. 6: 1236-44. PMID 16273099 DOI: 10.1038/Ni1268 |
0.814 |
|
| 2005 |
Gao Y, Tao J, Li MO, Zhang D, Chi H, Henegariu O, Kaech SM, Davis RJ, Flavell RA, Yin Z. JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance. Journal of Immunology (Baltimore, Md. : 1950). 175: 5783-9. PMID 16237070 DOI: 10.4049/Jimmunol.175.9.5783 |
0.62 |
|
| 2005 |
Chandele A, Kaech SM. Cutting edge: memory CD8 T cell maturation occurs independently of CD8alphaalpha. Journal of Immunology (Baltimore, Md. : 1950). 175: 5619-23. PMID 16237050 DOI: 10.4049/Jimmunol.175.9.5619 |
0.694 |
|
| 2005 |
Miller JD, Masopust D, Wherry EJ, Kaech S, Silvestri G, Ahmed R. Differentiation of CD8 T cells in response to acute and chronic viral infections: Implications for HIV vaccine development Current Drug Targets - Infectious Disorders. 5: 121-129. PMID 15975018 DOI: 10.2174/1568005054201544 |
0.735 |
|
| 2005 |
Manders PM, Hunter PJ, Telaranta AI, Carr JM, Marshall JL, Carrasco M, Murakami Y, Palmowski MJ, Cerundolo V, Kaech SM, Ahmed R, Fearon DT. BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 102: 7418-25. PMID 15833813 DOI: 10.1073/Pnas.0501585102 |
0.755 |
|
| 2005 |
Paiardini M, Cervasi B, Albrecht H, Muthukumar A, Dunham R, Gordon S, Radziewicz H, Piedimonte G, Magnani M, Montroni M, Kaech SM, Weintrob A, Altman JD, Sodora DL, Feinberg MB, et al. Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals. Journal of Immunology (Baltimore, Md. : 1950). 174: 2900-9. PMID 15728501 DOI: 10.4049/Jimmunol.174.5.2900 |
0.587 |
|
| 2005 |
Haining WN, Ebert B, Subramanian A, Kaech S, Nadler L, Golub T, Wherry EJ. Transcriptional Mapping of T Cell Memory Reveals That Chronic Viral Infection Arrests Memory Differentiation. Blood. 106: 328-328. DOI: 10.1182/Blood.V106.11.328.328 |
0.736 |
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| 2004 |
Wherry EJ, Barber DL, Kaech SM, Blattman JN, Ahmed R. Antigen-independent memory CD8 T cells do not develop during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. 101: 16004-9. PMID 15505208 DOI: 10.1073/Pnas.0407192101 |
0.86 |
|
| 2004 |
Sabbagh L, Kaech SM, Bourbonnière M, Woo M, Cohen LY, Haddad EK, Labrecque N, Ahmed R, Sékaly RP. The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 173: 5425-33. PMID 15494489 DOI: 10.4049/Jimmunol.173.9.5425 |
0.661 |
|
| 2004 |
Latner DR, Kaech SM, Ahmed R. Enhanced expression of cell cycle regulatory genes in virus-specific memory CD8+ T cells. Journal of Virology. 78: 10953-9. PMID 15452215 DOI: 10.1128/Jvi.78.20.10953-10959.2004 |
0.718 |
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| 2004 |
Masopust D, Kaech SM, Wherry EJ, Ahmed R. The role of programming in memory T-cell development. Current Opinion in Immunology. 16: 217-25. PMID 15023416 DOI: 10.1016/J.Coi.2004.02.005 |
0.772 |
|
| 2003 |
Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nature Immunology. 4: 1191-8. PMID 14625547 DOI: 10.1038/Ni1009 |
0.768 |
|
| 2003 |
Wan J, Martinvalet D, Ji X, Lois C, Kaech SM, Von Andrian UH, Lieberman J, Ahmed R, Manjunath N. The Bcl-2 family pro-apoptotic molecule, BNIP3 regulates activation-induced cell death of effector cytotoxic T lymphocytes. Immunology. 110: 10-7. PMID 12941136 DOI: 10.1046/J.1365-2567.2003.01710.X |
0.582 |
|
| 2003 |
Adams AB, Williams MA, Jones TR, Shirasugi N, Durham MM, Kaech SM, Wherry EJ, Onami T, Lanier JG, Kokko KE, Pearson TC, Ahmed R, Larsen CP. Heterologous immunity provides a potent barrier to transplantation tolerance. The Journal of Clinical Investigation. 111: 1887-95. PMID 12813024 DOI: 10.1172/Jci17477 |
0.83 |
|
| 2003 |
Kersh EN, Kaech SM, Onami TM, Moran M, Wherry EJ, Miceli MC, Ahmed R. TCR signal transduction in antigen-specific memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 5455-63. PMID 12759421 DOI: 10.4049/Jimmunol.170.11.5455 |
0.796 |
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| 2003 |
Antia R, Bergstrom CT, Pilyugin SS, Kaech SM, Ahmed R. Models of CD8+ responses: 1. What is the antigen-independent proliferation program. Journal of Theoretical Biology. 221: 585-98. PMID 12713942 DOI: 10.1006/Jtbi.2003.3208 |
0.673 |
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| 2003 |
Blattman JN, Grayson JM, Wherry EJ, Kaech SM, Smith KA, Ahmed R. Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nature Medicine. 9: 540-7. PMID 12692546 DOI: 10.1038/Nm866 |
0.816 |
|
| 2003 |
Kaech SM, Ahmed R. Immunology. CD8 T cells remember with a little help. Science (New York, N.Y.). 300: 263-5. PMID 12690179 DOI: 10.1126/Science.1084511 |
0.753 |
|
| 2003 |
Wherry EJ, Teichgräber V, Becker TC, Masopust D, Kaech SM, Antia R, von Andrian UH, Ahmed R. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nature Immunology. 4: 225-34. PMID 12563257 DOI: 10.1038/Ni889 |
0.831 |
|
| 2003 |
Shen H, Whitmire JK, Fan X, Shedlock DJ, Kaech SM, Ahmed R. A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes. Journal of Immunology (Baltimore, Md. : 1950). 170: 1443-51. PMID 12538706 DOI: 10.4049/Jimmunol.170.3.1443 |
0.744 |
|
| 2003 |
Hathcock KS, Kaech SM, Ahmed R, Hodes RJ. Induction of telomerase activity and maintenance of telomere length in virus-specific effector and memory CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 147-52. PMID 12496394 DOI: 10.4049/Jimmunol.170.1.147 |
0.758 |
|
| 2002 |
Kaech SM, Hemby S, Kersh E, Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation Cell. 111: 837-851. PMID 12526810 DOI: 10.1016/S0092-8674(02)01139-X |
0.767 |
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| 2002 |
Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nature Reviews. Immunology. 2: 251-62. PMID 12001996 DOI: 10.1038/Nri778 |
0.782 |
|
| 2002 |
Blattman JN, Antia R, Sourdive DJ, Wang X, Kaech SM, Murali-Krishna K, Altman JD, Ahmed R. Estimating the precursor frequency of naive antigen-specific CD8 T cells. The Journal of Experimental Medicine. 195: 657-64. PMID 11877489 DOI: 10.1084/Jem.20001021 |
0.816 |
|
| 2001 |
Kaech SM, Ahmed R. Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells. Nature Immunology. 2: 415-22. PMID 11323695 DOI: 10.1038/87720 |
0.746 |
|
| 1996 |
Simske JS, Kaech SM, Harp SA, Kim SK. LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction. Cell. 85: 195-204. PMID 8612272 DOI: 10.1016/S0092-8674(00)81096-X |
0.335 |
|
| 1990 |
Wyss A, Kaech S, Ballmer-Hofer K. Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen. Journal of Virology. 64: 5163-6. PMID 2168992 DOI: 10.1128/Jvi.64.10.5163-5166.1990 |
0.419 |
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