Jonathan G. Hoggatt, Ph.D. - Publications

Affiliations: 
2010 Microbiology & Immunology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Immunology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hoggatt J, Pelus LM. The Factory of Blood Production: Hematopoietic Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 2567: 3-7. PMID 36255691 DOI: 10.1007/978-1-0716-2679-5_1  0.664
2021 Menendez-Gonzalez JB, Hoggatt J. Hematopoietic Stem Cell Mobilization: Current Collection Approaches, Stem Cell Heterogeneity, and a Proposed New Method for Stem Cell Transplant Conditioning. Stem Cell Reviews and Reports. 17: 1939-1953. PMID 34661830 DOI: 10.1007/s12015-021-10272-1  0.493
2020 Patterson AM, Liu L, Sampson CH, Plett PA, Li H, Singh P, Mohammad KS, Hoggatt J, Capitano ML, Orschell CM, Pelus LM. A Single Radioprotective Dose of Prostaglandin E Blocks Irradiation-Induced Apoptotic Signaling and Early Cycling of Hematopoietic Stem Cells. Stem Cell Reports. PMID 32735825 DOI: 10.1016/J.Stemcr.2020.07.004  0.674
2020 Dipersio J, Devine S, Hoggatt J, Scadden D, Howell H, Schmelmer V, Neale J, Boitano T, Cooke M, Morrow D, Raffel G, Savage W, Goncalves K, Falahee P, Davis J. Fri0235 Phase 1 Clinical Study Of Mgta-145 In Combination With Plerixafor Shows Rapid Single-Day Mobilisation And Collection Of Cd34+ Haematopoietic Stem Cells Without G-Csf Annals of the Rheumatic Diseases. 79: 701-702. DOI: 10.1136/Annrheumdis-2020-Eular.3750  0.497
2020 DiPersio JF, Devine SM, Hoggatt J, Scadden D, Howell H, Schmelmer V, Neale J, Boitano AE, Cooke MP, Goncalves KA, Raffel GD, Savage W, Falahee PC, Morrow DM, Davis JC. Phase 1 Clinical Study of Mgta-145 in Combination with Plerixafor Shows Rapid Single-Day Mobilization and Collection of CD34+ HSCs without G-CSF Biology of Blood and Marrow Transplantation. 26: S55. DOI: 10.1016/J.Bbmt.2019.12.129  0.471
2019 Czechowicz A, Palchaudhuri R, Scheck A, Hu Y, Hoggatt J, Saez B, Pang WW, Mansour MK, Tate TA, Chan YY, Walck E, Wernig G, Shizuru JA, Winau F, Scadden DT, et al. Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation. Nature Communications. 10: 617. PMID 30728354 DOI: 10.1038/S41467-018-08201-X  0.493
2019 DiPersio JF, Hoggatt J, Devine S, Biernat L, Howell H, Schmelmer V, Neale JR, Boitano AE, Cooke MP, Goncalves KA, Raffel GD, Falahee PC, Morrow DM, Davis JC. Rapid and Robust Mobilization of CD34+ HSCs without G-CSF Following Administration of Mgta-145 Alone or in Combination with Plerixafor Blood. 134: 1961-1961. DOI: 10.1182/Blood-2019-127523  0.461
2018 Falahee P, Goncalves KA, Hyzy SL, Proctor JL, Hoggatt J, Morrow D, Cooke MP. The Combination of Groβt and AMD3100 Leads to Rapid and Robust Mobilization of Hematopoietic Stem Cells in Nonhuman Primates Biology of Blood and Marrow Transplantation. 24. DOI: 10.1016/J.Bbmt.2017.12.574  0.526
2017 Hoggatt J, Singh P, Tate TA, Chou BK, Datari SR, Fukuda S, Liu L, Kharchenko PV, Schajnovitz A, Baryawno N, Mercier FE, Boyer J, Gardner J, Morrow DM, Scadden DT, et al. Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell. Cell. PMID 29224778 DOI: 10.1016/J.Cell.2017.11.003  0.73
2017 Singh P, Hoggatt J, Kamocka MM, Mohammad KS, Saunders MR, Li H, Speth J, Carlesso N, Guise TA, Pelus LM. Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells. The Journal of Clinical Investigation. PMID 29130940 DOI: 10.1172/Jci94687  0.782
2016 Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, et al. Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators. Cell Stem Cell. PMID 27524439 DOI: 10.1016/J.Stem.2016.07.004  0.534
2016 Hoggatt J. Gene Therapy for "Bubble Boy" Disease. Cell. 166: 263. PMID 27419862 DOI: 10.1016/J.Cell.2016.06.049  0.32
2016 Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nature Biotechnology. PMID 27272386 DOI: 10.1038/Nbt.3584  0.56
2016 Hoggatt J, Kfoury Y, Scadden DT. Hematopoietic Stem Cell Niche in Health and Disease. Annual Review of Pathology. 11: 555-81. PMID 27193455 DOI: 10.1146/Annurev-Pathol-012615-044414  0.545
2016 Czechowicz A, Palchaudhuri R, Scheck A, Hoggatt J, Saez B, Scadden DT, Rossi DJ. Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins Blood. 128: 493-493. DOI: 10.1182/Blood.V128.22.493.493  0.498
2015 Hoggatt J, Hoggatt AF, Tate TA, Fortman J, Pelus LM. Bleeding the Laboratory Mouse: Not All Methods are Equal. Experimental Hematology. PMID 26644183 DOI: 10.1016/J.Exphem.2015.10.008  0.614
2015 Hoggatt J, Tate TA, Pelus LM. Role of lipegfilgrastim in the management of chemotherapy-induced neutropenia. International Journal of Nanomedicine. 10: 2647-52. PMID 25878498 DOI: 10.2147/Ijn.S55796  0.611
2015 Fukuda S, Hoggatt J, Singh P, Abe M, Speth JM, Hu P, Conway EM, Nucifora G, Yamaguchi S, Pelus LM. Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1. Leukemia. 29: 433-40. PMID 24903482 DOI: 10.1038/Leu.2014.183  0.795
2015 Silberstein L, Kharchenko PV, Kfoury YS, Mercier F, Turcotte R, Lin CP, Baryawno N, Severe N, Tate T, Hoggatt J, Scadden DT. Embigin Regulates HSPC Homing and Quiescence and Acts As a Cell Surface Marker for a Niche Factor-Enriched Subset of Osteolineage Cells Blood. 126: 663-663. DOI: 10.1182/Blood.V126.23.663.663  0.595
2015 Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Mansour MK, Scadden DT. Immunotoxin Enables Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplantation Blood. 126: 32-32. DOI: 10.1182/Blood.V126.23.32.32  0.514
2015 Rasmussen HK, Wong F, Tate T, Scadden DT, Hoggatt J. Oncostatin M Enhances Hematopoietic Stem Cell Homing and Engraftment Blood. 126: 31-31. DOI: 10.1182/Blood.V126.23.31.31  0.588
2014 Hoggatt J, Tate TA, Pelus LM. Hematopoietic stem and progenitor cell mobilization in mice. Methods in Molecular Biology (Clifton, N.J.). 1185: 43-64. PMID 25062621 DOI: 10.1007/978-1-4939-1133-2_4  0.723
2014 Speth JM, Hoggatt J, Singh P, Pelus LM. Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment. Blood. 123: 203-7. PMID 24167196 DOI: 10.1182/Blood-2013-07-516336  0.825
2014 Hoggatt J, Pelus LM. New G-CSF agonists for neutropenia therapy. Expert Opinion On Investigational Drugs. 23: 21-35. PMID 24073859 DOI: 10.1517/13543784.2013.838558  0.68
2014 Silberstein L, Kharchenko P, Kfoury Y, Mercier F, Osawa M, Hoggatt J, Tate T, Lin C, Scadden DT. Proximity-Based Single Cell Analysis of the Bone Marrow Niche Identifies Interleukin-18 As a Quiescence Regulator of Early Hematopoietic Progenitors Blood. 124: 773-773. DOI: 10.1182/Blood.V124.21.773.773  0.503
2013 Hoggatt J, Pelus LM. How beneficial is the use of NSAIDs in stem-cell transplantation? Expert Opinion On Pharmacotherapy. 14: 2453-6. PMID 24138174 DOI: 10.1517/14656566.2013.849243  0.723
2013 Hoggatt J, Speth JM, Pelus LM. Concise review: Sowing the seeds of a fruitful harvest: hematopoietic stem cell mobilization. Stem Cells (Dayton, Ohio). 31: 2599-606. PMID 24123398 DOI: 10.1002/Stem.1574  0.805
2013 Hoggatt J, Mohammad KS, Singh P, Pelus LM. Prostaglandin E2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness. Blood. 122: 2997-3000. PMID 24047650 DOI: 10.1182/Blood-2013-07-515288  0.686
2013 Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 122: 3074-81. PMID 23996087 DOI: 10.1182/Blood-2013-05-503177  0.693
2013 Zhao W, Breese E, Bowers A, Hoggatt J, Pelus LM, Broxmeyer HE, Goebl M, Harrington MA. SIMPL enhancement of tumor necrosis factor-α dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function. Plos One. 8: e61123. PMID 23630580 DOI: 10.1371/Journal.Pone.0061123  0.603
2013 Hoggatt J, Mohammad KS, Singh P, Hoggatt AF, Chitteti BR, Speth JM, Hu P, Poteat BA, Stilger KN, Ferraro F, Silberstein L, Wong FK, Farag SS, Czader M, Milne GL, et al. Differential stem- and progenitor-cell trafficking by prostaglandin E2. Nature. 495: 365-9. PMID 23485965 DOI: 10.1038/Nature11929  0.823
2013 Hoggatt J, Singh P, Stilger KN, Plett PA, Sampson CH, Chua HL, Orschell CM, Pelus LM. Recovery from hematopoietic injury by modulating prostaglandin E(2) signaling post-irradiation. Blood Cells, Molecules & Diseases. 50: 147-53. PMID 23206586 DOI: 10.1016/J.Bcmd.2012.11.006  0.682
2013 Speth JM, Capitano ML, Hoggatt J, Pelus LM. Hif1α and Rac1 Are Necessary For Enhanced HSPC Migration and Homing In Response To Prostaglandin E2 Treatment Blood. 122: 889-889. DOI: 10.1182/Blood.V122.21.889.889  0.735
2013 Singh P, Mohammad K, Hoggatt J, Speth JM, Pelus LM. Bone Marrow Sinusoidal Integrity Regulates Hematopoietic Stem and Progenitor Cell Trafficking Blood. 122: 3687-3687. DOI: 10.1182/Blood.V122.21.3687.3687  0.81
2012 Broxmeyer HE, Hoggatt J, O'Leary HA, Mantel C, Chitteti BR, Cooper S, Messina-Graham S, Hangoc G, Farag S, Rohrabaugh SL, Ou X, Speth J, Pelus LM, Srour EF, Campbell TB. Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis. Nature Medicine. 18: 1786-96. PMID 23160239 DOI: 10.1038/Nm.2991  0.796
2012 Hoggatt J, Scadden DT. The stem cell niche: tissue physiology at a single cell level. The Journal of Clinical Investigation. 122: 3029-34. PMID 22945635 DOI: 10.1172/Jci60238  0.449
2012 Hoggatt J, Pelus LM. Hematopoietic stem cell mobilization with agents other than G-CSF. Methods in Molecular Biology (Clifton, N.J.). 904: 49-67. PMID 22890921 DOI: 10.1007/978-1-61779-943-3_4  0.714
2012 Singh P, Hu P, Hoggatt J, Moh A, Pelus LM. Expansion of bone marrow neutrophils following G-CSF administration in mice results in osteolineage cell apoptosis and mobilization of hematopoietic stem and progenitor cells. Leukemia. 26: 2375-83. PMID 22543963 DOI: 10.1038/Leu.2012.117  0.735
2012 Singh P, Hoggatt J, Hu P, Speth JM, Fukuda S, Breyer RM, Pelus LM. Blockade of prostaglandin E2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells. Blood. 119: 1671-82. PMID 22110249 DOI: 10.1182/Blood-2011-03-342428  0.774
2012 Singh P, Hoggatt J, Hu P, Pelus LM. Sinusoidal Endothelial CD26 Cleavage of Neuropeptide Y Regulates Transendothelial Migration and Mobilization of Hematopoietic Stem and Progenitor Cells in Response to G-CSF. Blood. 120: 2347-2347. DOI: 10.1182/Blood.V120.21.2347.2347  0.663
2011 Pelus LM, Hoggatt J. Pleiotropic effects of prostaglandin E2 in hematopoiesis; prostaglandin E2 and other eicosanoids regulate hematopoietic stem and progenitor cell function. Prostaglandins & Other Lipid Mediators. 96: 3-9. PMID 21722751 DOI: 10.1016/J.Prostaglandins.2011.06.004  0.723
2011 Hoggatt J, Pelus LM. Many mechanisms mediating mobilization: an alliterative review. Current Opinion in Hematology. 18: 231-8. PMID 21537168 DOI: 10.1097/Moh.0B013E3283477962  0.717
2011 Pelus LM, Hoggatt J, Singh P. Pulse exposure of haematopoietic grafts to prostaglandin E2 in vitro facilitates engraftment and recovery. Cell Proliferation. 22-9. PMID 21481039 DOI: 10.1111/J.1365-2184.2010.00726.X  0.642
2011 Hoggatt J, Pelus LM. Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment. Stem Cell Research & Therapy. 2: 13. PMID 21418553 DOI: 10.1186/Scrt54  0.735
2011 Speth JM, Hoggatt J, Pelus LM. Enhanced Homing of HSPCs After Treatment with Prostaglandin E2 (PGE2) May Be An Effect of Transcriptional Regulation of CXC Chemokine Receptor 4 (CXCR4) Through Hypoxia Inducible Factor 1α (HIF1α) Blood. 118: 918-918. DOI: 10.1182/Blood.V118.21.918.918  0.817
2011 Hoggatt J, Mohammad KS, Chitteti BR, Singh P, Speth JM, Hu P, Poteat B, Srour E, Guise T, Pelus LM. Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms Blood. 118: 724-724. DOI: 10.1182/Blood.V118.21.724.724  0.815
2010 Hoggatt J, Pelus LM. Eicosanoid regulation of hematopoiesis and hematopoietic stem and progenitor trafficking. Leukemia. 24: 1993-2002. PMID 20882043 DOI: 10.1038/Leu.2010.216  0.752
2010 Hoggatt AF, Hoggatt J, Honerlaw M, Pelus LM. A spoonful of sugar helps the medicine go down: a novel technique to improve oral gavage in mice. Journal of the American Association For Laboratory Animal Science : Jaalas. 49: 329-34. PMID 20587165  0.491
2010 Fukuda S, Singh P, Hoggatt J, Speth J, Abe M, Conway EM, Crispino J, Nucifora G, Yamaguchi S, Pelus LM. Survivin Modulates Gene Expression That Connects through An Extensive Functional Signaling Network and Regulates Proliferation of Hematopoietic Stem Cells through Evi-1 Blood. 116: 87-87. DOI: 10.1182/Blood.V116.21.87.87  0.803
2010 Hoggatt J, Chitteti BR, Krishna V, Farag S, Czader M, Yoder MC, Srour E, Pelus LM. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Alter the Hematopoietic Niche and Treatment In Healthy Volunteers Results In Mobilization of CD34+ Cells, Hematopoietic Colony Forming Cells, and Endothelial Colony Forming Cells Blood. 116: 556-556. DOI: 10.1182/Blood.V116.21.556.556  0.729
2010 Hoggatt J, Plett A, Sampson C, Chua HL, Orschell CM, Pelus LM. Recovery of Hematopoiesis and Increased Survival Following Radiological Injury through Modulation of Prostaglandin E2 (PGE2) Signaling. Blood. 116: 2638-2638. DOI: 10.1182/Blood.V116.21.2638.2638  0.644
2010 Singh, P, Hoggatt J, Speth J, Pelus LM. Prostaglandin E2 Modulates Monocytes and Dendritic Cells Specific Progenitor Cell (MDP) Fate by Regulating M-CSF Receptor and Flt3 Receptor Expression. Blood. 116: 2636-2636. DOI: 10.1182/Blood.V116.21.2636.2636  0.789
2009 Hoggatt J, Singh P, Sampath J, Pelus LM. Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation. Blood. 113: 5444-55. PMID 19324903 DOI: 10.1182/Blood-2009-01-201335  0.731
2009 Hoggatt J, Singh P, Hoggatt A, Speth JM, Pelus LM. Inhibition of Prostaglandin E2 (PGE2) Signaling by Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or EP4 Receptor Antagonism Expands Hematopoietic Stem and Progenitor Cells (HSPC) and Enhances Their Mobilization to Peripheral Blood in Mice and Baboons. Blood. 114: 84-84. DOI: 10.1182/Blood.V114.22.84.84  0.795
2009 Broxmeyer HE, Hoggatt J, Cooper S, Hangoc G, Pelus LM, Campbell TB. CD26/Dipeptidylpeptidase IV Regulates Potency of Selected Hematopoietic Growth Factors through Truncation, and Recovery In Vivo After Cytotoxic Stress. Blood. 114: 3602-3602. DOI: 10.1182/Blood.V114.22.3602.3602  0.668
2009 Singh P, Hoggatt J, Speth JM, Pelus LM. Cyclooxygenase-2 Derived Prostaglandin E2 Is Required for Dendritic Cell Differentiation From Hematopoietic Progenitor Cells. Blood. 114: 1499-1499. DOI: 10.1182/Blood.V114.22.1499.1499  0.783
2008 Hoggatt J, Singh P, Sampath J, Pelus LM. Prostaglandin E2 Enhances Survival, Proliferation, Homing and Engraftment of Mouse Hematopoietic Stem Cells Blood. 112: 74-74. DOI: 10.1182/Blood.V112.11.74.74  0.752
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