| Year |
Citation |
Score |
| 2024 |
Yao G, Parris MR, Kuo WC, Pörzgen P, Castillo B, Mason ES, Chinchilla A, Huang J, Suzuki S, Ross R, Akana E, Vander Schuit S, Miller SP, Penner R, Sun HS, ... ... Fleig A, et al. Transient Receptor Potential Melastatin 7 (TRPM7) Ion Channel Inhibitors: Preliminary SAR and Conformational Studies of Xenicane Diterpenoids from the Hawaiian Soft Coral . Journal of Natural Products. PMID 38537009 DOI: 10.1021/acs.jnatprod.3c00942 |
0.613 |
|
| 2023 |
Suzuki S, Wakano C, Monteilh-Zoller MK, Cullen AJ, Fleig A, Penner R. Cannabigerolic Acid (CBGA) Inhibits the TRPM7 Ion Channel Through its Kinase Domain. Function (Oxford, England). 5: zqad069. PMID 38162115 DOI: 10.1093/function/zqad069 |
0.717 |
|
| 2023 |
Khalil A, Shekh-Ahmad T, Kovac S, Wykes RC, Horgen FD, Fleig A, Walker MC. Drugs acting at TRPM7 channels inhibit seizure-like activity. Epilepsia Open. PMID 37328275 DOI: 10.1002/epi4.12773 |
0.34 |
|
| 2023 |
Suzuki S, Fleig A, Penner R. CBGA ameliorates inflammation and fibrosis in nephropathy. Scientific Reports. 13: 6341. PMID 37072467 DOI: 10.1038/s41598-023-33507-2 |
0.549 |
|
| 2022 |
Faouzi M, Wakano C, Monteilh-Zoller MK, Neupane RP, Starkus JG, Neupane JB, Cullen AJ, Johnson BE, Fleig A, Penner R. Acidic Cannabinoids Suppress Proinflammatory Cytokine Release by Blocking Store-operated Calcium Entry. Function (Oxford, England). 3: zqac033. PMID 35910331 DOI: 10.1093/function/zqac033 |
0.642 |
|
| 2022 |
Ji D, Fleig A, Horgen FD, Feng ZP, Sun HS. Modulators of TRPM7 and its potential as a drug target for brain tumours. Cell Calcium. 101: 102521. PMID 34953296 DOI: 10.1016/j.ceca.2021.102521 |
0.311 |
|
| 2021 |
Meng S, Alanazi R, Ji D, Bandura J, Luo ZW, Fleig A, Feng ZP, Sun HS. Role of TRPM7 kinase in cancer. Cell Calcium. 96: 102400. PMID 33784560 DOI: 10.1016/j.ceca.2021.102400 |
0.304 |
|
| 2020 |
Sun HS, Horgen FD, Romo D, Hull KG, Kiledal SA, Fleig A, Feng ZP. Waixenicin A, a marine-derived TRPM7 inhibitor: a promising CNS drug lead. Acta Pharmacologica Sinica. PMID 32994545 DOI: 10.1038/s41401-020-00512-4 |
0.347 |
|
| 2020 |
Turlova E, Wong R, Xu B, Li F, Du L, Habbous S, Horgen FD, Fleig A, Feng ZP, Sun HS. TRPM7 Mediates Neuronal Cell Death Upstream of Calcium/Calmodulin-Dependent Protein Kinase II and Calcineurin Mechanism in Neonatal Hypoxic-Ischemic Brain Injury. Translational Stroke Research. PMID 32430797 DOI: 10.1007/s12975-020-00810-3 |
0.387 |
|
| 2020 |
Ardestani G, Mehregan A, Fleig A, Horgen FD, Carvacho I, Fissore RA. Divalent cation influx and calcium homeostasis in germinal vesicle mouse oocytes. Cell Calcium. 87: 102181. PMID 32097818 DOI: 10.1016/J.Ceca.2020.102181 |
0.561 |
|
| 2020 |
Suzuki S, Penner R, Fleig A. TRPM7 contributes to progressive nephropathy. Scientific Reports. 10: 2333. PMID 32047249 DOI: 10.1038/s41598-020-59355-y |
0.625 |
|
| 2019 |
Gautier M, Trebak M, Fleig A, Vandier C, Ouadid-Ahidouch H. Ca channels in cancer. Cell Calcium. 84: 102083. PMID 31606459 DOI: 10.1016/J.Ceca.2019.102083 |
0.515 |
|
| 2019 |
Gautier M, Trebak M, Fleig A, Vandier C, Ouadid-Ahidouch H. Ca homeostasis and cancer. Cell Calcium. 84: 102084. PMID 31593838 DOI: 10.1016/J.Ceca.2019.102084 |
0.387 |
|
| 2018 |
Huang Y, Leng TD, Inoue K, Yang T, Liu M, Horgen FD, Fleig A, Li J, Xiong ZG. TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis. The Journal of Biological Chemistry. PMID 30076216 DOI: 10.1074/jbc.RA117.001032 |
0.397 |
|
| 2018 |
Suzuki S, Lis A, Schmitz C, Penner R, Fleig A. The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins. Cellular and Molecular Life Sciences : Cmls. PMID 29500477 DOI: 10.1007/s00018-018-2786-z |
0.68 |
|
| 2017 |
Starkus JG, Poerzgen P, Layugan K, Kawabata KG, Goto JI, Suzuki S, Myers G, Kelly M, Penner R, Fleig A, Horgen FD. Scalaradial Is a Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels. Journal of Natural Products. PMID 29019677 DOI: 10.1021/acs.jnatprod.7b00515 |
0.722 |
|
| 2017 |
Huang J, Furuya H, Faouzi M, Zhang Z, Monteilh-Zoller M, Kawabata KG, David Horgen F, Kawamori T, Penner R, Fleig A. Erratum to: Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice. Cell Communication and Signaling : Ccs. 15: 31. PMID 28893271 DOI: 10.1186/s12964-017-0188-8 |
0.542 |
|
| 2017 |
Huang J, Furuya H, Faouzi M, Zhang Z, Monteilh-Zoller M, Kelly Galbraith Kawabata F, Horgen D, Kawamori T, Penner R, Fleig A. Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice. Cell Communication and Signaling : Ccs. 15: 30. PMID 28810912 DOI: 10.1186/s12964-017-0187-9 |
0.66 |
|
| 2017 |
Fleig A, Parekh AB. New insights into Ca(2+) channel function in health and disease. The Journal of Physiology. 595: 2997-2998. PMID 28503825 DOI: 10.1113/JP274289 |
0.481 |
|
| 2017 |
Faouzi M, Kilch T, Horgen FD, Fleig A, Penner R. The TRPM7 channel kinase regulates store-operated calcium entry. The Journal of Physiology. PMID 28130783 DOI: 10.1113/JP274006 |
0.758 |
|
| 2016 |
Jansen C, Sahni J, Suzuki S, Horgen FD, Penner R, Fleig A. The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity. Scientific Reports. 6: 33459. PMID 27628598 DOI: 10.1038/srep33459 |
0.705 |
|
| 2016 |
Sponder G, Mastrototaro L, Kurth K, Merolle L, Zhang Z, Abdulhanan N, Smorodchenko A, Wolf K, Fleig A, Penner R, Iotti S, Aschenbach JR, Vormann J, Kolisek M. Human CNNM2 is not a Mg(2+) transporter per se. Pflugers Archiv : European Journal of Physiology. PMID 27068403 DOI: 10.1007/s00424-016-1816-7 |
0.604 |
|
| 2015 |
Zierler S, Sumoza-Toledo A, Suzuki S, Ó Dúill F, Ryazanova LV, Penner R, Ryazanov AG, Fleig A. TRPM7 kinase activity regulates murine mast cell degranulation. The Journal of Physiology. PMID 26660477 DOI: 10.1113/Jp271564 |
0.716 |
|
| 2014 |
Ryazanova LV, Hu Z, Suzuki S, Chubanov V, Fleig A, Ryazanov AG. Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice. Scientific Reports. 4: 7599. PMID 25534891 DOI: 10.1038/Srep07599 |
0.377 |
|
| 2014 |
Turlova E, Bae CY, Deurloo M, Chen W, Barszczyk A, Horgen FD, Fleig A, Feng ZP, Sun HS. TRPM7 Regulates Axonal Outgrowth and Maturation of Primary Hippocampal Neurons. Molecular Neurobiology. PMID 25502295 DOI: 10.1007/s12035-014-9032-y |
0.401 |
|
| 2014 |
Zhang Z, Faouzi M, Huang J, Geerts D, Yu H, Fleig A, Penner R. N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation. Oncotarget. 5: 7625-34. PMID 25277194 DOI: 10.18632/ONCOTARGET.2283 |
0.726 |
|
| 2014 |
Beck A, Fleig A, Penner R, Peinelt C. Regulation of endogenous and heterologous Ca²⁺ release-activated Ca²⁺ currents by pH. Cell Calcium. 56: 235-43. PMID 25168908 DOI: 10.1016/j.ceca.2014.07.011 |
0.7 |
|
| 2014 |
Zhang Z, Yu H, Huang J, Faouzi M, Schmitz C, Penner R, Fleig A. The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels. The Journal of Biological Chemistry. 289: 5217-27. PMID 24385424 DOI: 10.1074/jbc.M113.512285 |
0.722 |
|
| 2013 |
Visser D, Langeslag M, Kedziora KM, Klarenbeek J, Kamermans A, Horgen FD, Fleig A, van Leeuwen FN, Jalink K. TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells. Cell Calcium. 54: 404-15. PMID 24176224 DOI: 10.1016/j.ceca.2013.09.003 |
0.529 |
|
| 2013 |
Sumoza-Toledo A, Fleig A, Penner R. TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice. Journal of Inflammation (London, England). 10: 19. PMID 23631390 DOI: 10.1186/1476-9255-10-19 |
0.637 |
|
| 2013 |
Yu H, Zhang Z, Lis A, Penner R, Fleig A. TRPM7 is regulated by halides through its kinase domain. Cellular and Molecular Life Sciences : Cmls. 70: 2757-71. PMID 23471296 DOI: 10.1007/s00018-013-1284-6 |
0.719 |
|
| 2011 |
Zierler S, Yao G, Zhang Z, Kuo WC, Pörzgen P, Penner R, Horgen FD, Fleig A. Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels. The Journal of Biological Chemistry. 286: 39328-35. PMID 21926172 DOI: 10.1074/jbc.M111.264341 |
0.744 |
|
| 2011 |
Sumoza-Toledo A, Lange I, Cortado H, Bhagat H, Mori Y, Fleig A, Penner R, Partida-Sánchez S. Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3529-42. PMID 21753080 DOI: 10.1096/fj.10-178483 |
0.711 |
|
| 2010 |
Lis A, Zierler S, Peinelt C, Fleig A, Penner R. A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating. The Journal of General Physiology. 136: 673-86. PMID 21115697 DOI: 10.1085/jgp.201010484 |
0.702 |
|
| 2010 |
Ryazanova LV, Rondon LJ, Zierler S, Hu Z, Galli J, Yamaguchi TP, Mazur A, Fleig A, Ryazanov AG. TRPM7 is essential for Mg(2+) homeostasis in mammals. Nature Communications. 1: 109. PMID 21045827 DOI: 10.1038/Ncomms1108 |
0.394 |
|
| 2010 |
Grupe M, Myers G, Penner R, Fleig A. Activation of store-operated I(CRAC) by hydrogen peroxide. Cell Calcium. 48: 1-9. PMID 20646759 DOI: 10.1016/j.ceca.2010.05.005 |
0.745 |
|
| 2010 |
Castillo B, Pörzgen P, Penner R, Horgen FD, Fleig A. Development and optimization of a high-throughput bioassay for TRPM7 ion channel inhibitors. Journal of Biomolecular Screening. 15: 498-507. PMID 20413646 DOI: 10.1177/1087057110368294 |
0.675 |
|
| 2010 |
Brixel LR, Monteilh-Zoller MK, Ingenbrandt CS, Fleig A, Penner R, Enklaar T, Zabel BU, Prawitt D. TRPM5 regulates glucose-stimulated insulin secretion. PflüGers Archiv : European Journal of Physiology. 460: 69-76. PMID 20393858 DOI: 10.1007/s00424-010-0835-z |
0.621 |
|
| 2010 |
Starkus JG, Fleig A, Penner R. The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification. The Journal of Physiology. 588: 1227-40. PMID 20194125 DOI: 10.1113/jphysiol.2010.187476 |
0.762 |
|
| 2010 |
Goto J, Suzuki AZ, Ozaki S, Matsumoto N, Nakamura T, Ebisui E, Fleig A, Penner R, Mikoshiba K. Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca(2+) entry via STIM proteins. Cell Calcium. 47: 1-10. PMID 19945161 DOI: 10.1016/j.ceca.2009.10.004 |
0.681 |
|
| 2009 |
Lange I, Yamamoto S, Partida-Sanchez S, Mori Y, Fleig A, Penner R. TRPM2 functions as a lysosomal Ca2+-release channel in beta cells. Science Signaling. 2: ra23. PMID 19454650 DOI: 10.1126/scisignal.2000278 |
0.743 |
|
| 2009 |
Peinelt C, Beck A, Monteilh-Zoller MK, Penner R, Fleig A. IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC). Cell Calcium. 45: 326-30. PMID 19157540 DOI: 10.1016/j.ceca.2008.12.001 |
0.679 |
|
| 2008 |
Ren YR, Pan F, Parvez S, Fleig A, Chong CR, Xu J, Dang Y, Zhang J, Jiang H, Penner R, Liu JO. Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes. Plos One. 3: e4009. PMID 19104661 DOI: 10.1371/Journal.Pone.0004009 |
0.682 |
|
| 2008 |
Lange I, Penner R, Fleig A, Beck A. Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils. Cell Calcium. 44: 604-15. PMID 18572241 DOI: 10.1016/j.ceca.2008.05.001 |
0.727 |
|
| 2008 |
Yamamoto S, Shimizu S, Kiyonaka S, Takahashi N, Wajima T, Hara Y, Negoro T, Hiroi T, Kiuchi Y, Okada T, Kaneko S, Lange I, Fleig A, Penner R, Nishi M, et al. TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nature Medicine. 14: 738-47. PMID 18542050 DOI: 10.1038/nm1758 |
0.685 |
|
| 2008 |
Peinelt C, Lis A, Beck A, Fleig A, Penner R. 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. The Journal of Physiology. 586: 3061-73. PMID 18403424 DOI: 10.1113/jphysiol.2008.151365 |
0.756 |
|
| 2008 |
Kolisek M, Launay P, Beck A, Sponder G, Serafini N, Brenkus M, Froschauer EM, Martens H, Fleig A, Schweigel M. SLC41A1 is a novel mammalian Mg2+ carrier. The Journal of Biological Chemistry. 283: 16235-47. PMID 18367447 DOI: 10.1074/jbc.M707276200 |
0.417 |
|
| 2008 |
Beck A, Penner R, Fleig A. Lipopolysaccharide-induced down-regulation of Ca2+ release-activated Ca2+ currents (I CRAC) but not Ca2+-activated TRPM4-like currents (I CAN) in cultured mouse microglial cells. The Journal of Physiology. 586: 427-39. PMID 17991695 DOI: 10.1113/jphysiol.2007.145151 |
0.71 |
|
| 2008 |
Parvez S, Beck A, Peinelt C, Soboloff J, Lis A, Monteilh-Zoller M, Gill DL, Fleig A, Penner R. STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 752-61. PMID 17905723 DOI: 10.1096/Fj.07-9449Com |
0.742 |
|
| 2007 |
Starkus J, Beck A, Fleig A, Penner R. Regulation of TRPM2 by extra- and intracellular calcium. The Journal of General Physiology. 130: 427-40. PMID 17893195 DOI: 10.1085/jgp.200709836 |
0.738 |
|
| 2007 |
Bessac BF, Fleig A. TRPM7 channel is sensitive to osmotic gradients in human kidney cells. The Journal of Physiology. 582: 1073-86. PMID 17510191 DOI: 10.1113/jphysiol.2007.130534 |
0.831 |
|
| 2007 |
Lis A, Peinelt C, Beck A, Parvez S, Monteilh-Zoller M, Fleig A, Penner R. CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties. Current Biology : Cb. 17: 794-800. PMID 17442569 DOI: 10.1016/j.cub.2007.03.065 |
0.755 |
|
| 2007 |
Penner R, Fleig A. The Mg2+ and Mg(2+)-nucleotide-regulated channel-kinase TRPM7. Handbook of Experimental Pharmacology. 313-28. PMID 17217066 DOI: 10.1007/978-3-540-34891-7_19 |
0.722 |
|
| 2007 |
Tani D, Monteilh-Zoller MK, Fleig A, Penner R. Cell cycle-dependent regulation of store-operated I(CRAC) and Mg2+-nucleotide-regulated MagNuM (TRPM7) currents. Cell Calcium. 41: 249-60. PMID 17064762 DOI: 10.1016/j.ceca.2006.07.004 |
0.649 |
|
| 2007 |
Cheng H, Beck A, Launay P, Gross SA, Stokes AJ, Kinet JP, Fleig A, Penner R. TRPM4 controls insulin secretion in pancreatic beta-cells. Cell Calcium. 41: 51-61. PMID 16806463 DOI: 10.1016/J.Ceca.2006.04.032 |
0.7 |
|
| 2006 |
Vig M, Beck A, Billingsley JM, Lis A, Parvez S, Peinelt C, Koomoa DL, Soboloff J, Gill DL, Fleig A, Kinet JP, Penner R. CRACM1 multimers form the ion-selective pore of the CRAC channel. Current Biology : Cb. 16: 2073-9. PMID 16978865 DOI: 10.1016/J.Cub.2006.08.085 |
0.737 |
|
| 2006 |
Peinelt C, Vig M, Koomoa DL, Beck A, Nadler MJ, Koblan-Huberson M, Lis A, Fleig A, Penner R, Kinet JP. Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nature Cell Biology. 8: 771-3. PMID 16733527 DOI: 10.1038/Ncb1435 |
0.663 |
|
| 2006 |
Vig M, Peinelt C, Beck A, Koomoa DL, Rabah D, Koblan-Huberson M, Kraft S, Turner H, Fleig A, Penner R, Kinet JP. CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry. Science (New York, N.Y.). 312: 1220-3. PMID 16645049 DOI: 10.1126/Science.1127883 |
0.722 |
|
| 2006 |
Beck A, Kolisek M, Bagley LA, Fleig A, Penner R. Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 962-4. PMID 16585058 DOI: 10.1096/fj.05-5538fje |
0.745 |
|
| 2006 |
Demeuse P, Penner R, Fleig A. TRPM7 channel is regulated by magnesium nucleotides via its kinase domain. The Journal of General Physiology. 127: 421-34. PMID 16533898 DOI: 10.1085/jgp.200509410 |
0.708 |
|
| 2006 |
Stokes A, Wakano C, Koblan-Huberson M, Adra CN, Fleig A, Turner H. TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD. Cellular Signalling. 18: 1584-94. PMID 16500080 DOI: 10.1016/J.Cellsig.2005.12.009 |
0.371 |
|
| 2006 |
Takezawa R, Cheng H, Beck A, Ishikawa J, Launay P, Kubota H, Kinet JP, Fleig A, Yamada T, Penner R. A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity. Molecular Pharmacology. 69: 1413-20. PMID 16407466 DOI: 10.1124/Mol.105.021154 |
0.75 |
|
| 2005 |
Kolisek M, Beck A, Fleig A, Penner R. Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels. Molecular Cell. 18: 61-9. PMID 15808509 DOI: 10.1016/j.molcel.2005.02.033 |
0.748 |
|
| 2004 |
Launay P, Cheng H, Srivatsan S, Penner R, Fleig A, Kinet JP. TRPM4 regulates calcium oscillations after T cell activation. Science (New York, N.Y.). 306: 1374-7. PMID 15550671 DOI: 10.1126/Science.1098845 |
0.722 |
|
| 2004 |
Fleig A, Penner R. The TRPM ion channel subfamily: molecular, biophysical and functional features. Trends in Pharmacological Sciences. 25: 633-9. PMID 15530641 DOI: 10.1016/j.tips.2004.10.004 |
0.723 |
|
| 2004 |
Penner R, Fleig A. Store-operated calcium entry: a tough nut to CRAC. Science's Stke : Signal Transduction Knowledge Environment. 2004: pe38. PMID 15280580 DOI: 10.1126/stke.2432004pe38 |
0.691 |
|
| 2004 |
Horne G, Maechling C, Fleig A, Hirata M, Penner R, Spiess B, Potter BV. D-6-Deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, a mimic of d-myo-inositol 1,3,4,5-tetrakisphosphate: biological activity and pH-dependent conformational properties. Biochemical and Biophysical Research Communications. 320: 1262-70. PMID 15249226 DOI: 10.1016/J.Bbrc.2004.06.079 |
0.564 |
|
| 2004 |
Fleig A, Penner R. Emerging roles of TRPM channels. Novartis Foundation Symposium. 258: 248-58; discussion 2. PMID 15104187 DOI: 10.1002/0470862580.Ch18 |
0.713 |
|
| 2004 |
Takezawa R, Schmitz C, Demeuse P, Scharenberg AM, Penner R, Fleig A. Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain. Proceedings of the National Academy of Sciences of the United States of America. 101: 6009-14. PMID 15069188 DOI: 10.1073/pnas.0307565101 |
0.684 |
|
| 2004 |
Schmitz C, Perraud AL, Fleig A, Scharenberg AM. Dual-function ion channel/protein kinases: novel components of vertebrate magnesium regulatory mechanisms. Pediatric Research. 55: 734-7. PMID 14764909 DOI: 10.1203/01.PDR.0000117848.37520.A2 |
0.437 |
|
| 2003 |
Prawitt D, Monteilh-Zoller MK, Brixel L, Spangenberg C, Zabel B, Fleig A, Penner R. TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i. Proceedings of the National Academy of Sciences of the United States of America. 100: 15166-71. PMID 14634208 DOI: 10.1073/pnas.2334624100 |
0.758 |
|
| 2003 |
Schmitz C, Perraud AL, Johnson CO, Inabe K, Smith MK, Penner R, Kurosaki T, Fleig A, Scharenberg AM. Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7. Cell. 114: 191-200. PMID 12887921 DOI: 10.1016/S0092-8674(03)00556-7 |
0.691 |
|
| 2003 |
Turner H, Fleig A, Stokes A, Kinet JP, Penner R. Discrimination of intracellular calcium store subcompartments using TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) release channel activity. The Biochemical Journal. 371: 341-50. PMID 12513687 DOI: 10.1042/Bj20021381 |
0.696 |
|
| 2003 |
Monteilh-Zoller MK, Hermosura MC, Nadler MJ, Scharenberg AM, Penner R, Fleig A. TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. The Journal of General Physiology. 121: 49-60. PMID 12508053 DOI: 10.1085/jgp.20028740 |
0.684 |
|
| 2002 |
Launay P, Fleig A, Perraud AL, Scharenberg AM, Penner R, Kinet JP. TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization. Cell. 109: 397-407. PMID 12015988 DOI: 10.1016/S0092-8674(02)00719-5 |
0.756 |
|
| 2002 |
Mori Y, Wakamori M, Miyakawa T, Hermosura M, Hara Y, Nishida M, Hirose K, Mizushima A, Kurosaki M, Mori E, Gotoh K, Okada T, Fleig A, Penner R, Iino M, et al. Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes. The Journal of Experimental Medicine. 195: 673-81. PMID 11901194 DOI: 10.1084/jem.20011758 |
0.71 |
|
| 2002 |
Hermosura MC, Monteilh-Zoller MK, Scharenberg AM, Penner R, Fleig A. Dissociation of the store-operated calcium current I(CRAC) and the Mg-nucleotide-regulated metal ion current MagNuM. The Journal of Physiology. 539: 445-58. PMID 11882677 DOI: 10.1113/jphysiol.2001.013361 |
0.731 |
|
| 2001 |
Voets T, Prenen J, Fleig A, Vennekens R, Watanabe H, Hoenderop JG, Bindels RJ, Droogmans G, Penner R, Nilius B. CaT1 and the calcium release-activated calcium channel manifest distinct pore properties. The Journal of Biological Chemistry. 276: 47767-70. PMID 11687570 DOI: 10.1074/jbc.C100607200 |
0.749 |
|
| 2001 |
Perraud AL, Fleig A, Dunn CA, Bagley LA, Launay P, Schmitz C, Stokes AJ, Zhu Q, Bessman MJ, Penner R, Kinet JP, Scharenberg AM. ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. Nature. 411: 595-9. PMID 11385575 DOI: 10.1038/35079100 |
0.713 |
|
| 2001 |
Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM, Fleig A. LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature. 411: 590-5. PMID 11385574 DOI: 10.1038/35079092 |
0.724 |
|
| 2001 |
Nadler MJS, Hermosura MC, Inabe K, Perraud A, Zhu Q, Stokes AJ, Kurosaki T, Kinet J, Penner R, Scharenberg AM, Fleig A. Erratum: LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability Nature. 412: 660-660. DOI: 10.1038/35088104 |
0.68 |
|
| 2000 |
Hermosura MC, Takeuchi H, Fleig A, Riley AM, Potter BV, Hirata M, Penner R. InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase. Nature. 408: 735-40. PMID 11130077 DOI: 10.1038/35047115 |
0.713 |
|
| 1998 |
Mathes C, Fleig A, Penner R. Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine. The Journal of Biological Chemistry. 273: 25020-30. PMID 9737958 DOI: 10.1074/jbc.273.39.25020 |
0.675 |
|
| 1997 |
Parekh AB, Fleig A, Penner R. The store-operated calcium current I(CRAC): nonlinear activation by InsP3 and dissociation from calcium release. Cell. 89: 973-80. PMID 9200615 DOI: 10.1016/S0092-8674(00)80282-2 |
0.701 |
|
| 1997 |
Ruben PC, Fleig A, Featherstone D, Starkus JG, Rayner MD. Effects of clamp rise-time on rat brain IIA sodium channels in Xenopus oocytes. Journal of Neuroscience Methods. 73: 113-22. PMID 9196281 DOI: 10.1016/S0165-0270(96)02216-9 |
0.807 |
|
| 1997 |
Suda N, Franzius D, Fleig A, Nishimura S, Bödding M, Hoth M, Takeshima H, Penner R. Ca2+-induced Ca2+ release in Chinese hamster ovary (CHO) cells co-expressing dihydropyridine and ryanodine receptors. The Journal of General Physiology. 109: 619-31. PMID 9154908 DOI: 10.1085/jgp.109.5.619 |
0.723 |
|
| 1996 |
Fleig A, Takeshima H, Penner R. Absence of Ca2+ current facilitation in skeletal muscle of transgenic mice lacking the type 1 ryanodine receptor. The Journal of Physiology. 496: 339-45. PMID 8910220 DOI: 10.1113/Jphysiol.1996.Sp021689 |
0.701 |
|
| 1996 |
Fleig A, Penner R. Silent calcium channels generate excessive tail currents and facilitation of calcium currents in rat skeletal myoballs. The Journal of Physiology. 494: 141-53. PMID 8814612 DOI: 10.1113/Jphysiol.1996.Sp021481 |
0.697 |
|
| 1995 |
Fleig A, Penner R. Excessive repolarization-dependent calcium currents induced by strong depolarizations in rat skeletal myoballs. The Journal of Physiology. 489: 41-53. PMID 8583414 DOI: 10.1113/Jphysiol.1995.Sp021028 |
0.718 |
|
| 1994 |
Fleig A, Fitch JM, Goldin AL, Rayner MD, Starkus JG, Ruben PC. Point mutations in IIS4 alter activation and inactivation of rat brain IIA Na channels in Xenopus oocyte macropatches. Pflã¼Gers Archiv : European Journal of Physiology. 427: 406-13. PMID 7971139 DOI: 10.1007/Bf00374254 |
0.739 |
|
| 1994 |
Fleig A, Ruben PC, Rayner MD. Kinetic mode switch of rat brain IIA Na channels in Xenopus oocytes excised macropatches. Pflã¼Gers Archiv : European Journal of Physiology. 427: 399-405. PMID 7971138 DOI: 10.1007/BF00374253 |
0.734 |
|
| 1993 |
Starkus JG, Rayner MD, Fleig A, Ruben PC. Fast and slow inactivation of sodium channels: effects of photodynamic modification by methylene blue. Biophysical Journal. 65: 715-26. PMID 8218899 DOI: 10.1016/S0006-3495(93)81098-1 |
0.715 |
|
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