Year |
Citation |
Score |
2024 |
Olazabal-Herrero A, He B, Kwon Y, Gupta AK, Dutta A, Huang Y, Boddu P, Liang Z, Liang F, Teng Y, Lan L, Chen X, Pei H, Pillai MM, Sung P, ... Kupfer GM, et al. The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export. Cell Reports. 43: 113610. PMID 38165804 DOI: 10.1016/j.celrep.2023.113610 |
0.321 |
|
2020 |
Liang F, Miller AS, Tang C, Maranon D, Williamson EA, Hromas R, Wiese C, Zhao W, Sung P, Kupfer GM. The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair. The Journal of Biological Chemistry. PMID 32350107 DOI: 10.1074/Jbc.Ra120.013714 |
0.444 |
|
2019 |
Liang F, Miller AS, Longerich S, Tang C, Maranon D, Williamson EA, Hromas R, Wiese C, Kupfer GM, Sung P. DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response. Nature Communications. 10: 2849. PMID 31253762 DOI: 10.1038/S41467-019-10408-5 |
0.448 |
|
2019 |
Liang Z, Liang F, Teng Y, Chen X, Liu J, Longerich S, Rao T, Green AM, Collins NB, Xiong Y, Lan L, Sung P, Kupfer GM. Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination. Cell Reports. 26: 564-572.e5. PMID 30650351 DOI: 10.1016/J.Celrep.2018.12.084 |
0.355 |
|
2019 |
Liang F, Miller AS, Tang C, Sung P, Kupfer GM. UAF1 DNA Binding Activity Is Critical for RAD51-Mediated Homologous DNA Pairing Blood. 134: 2497-2497. DOI: 10.1182/Blood-2019-130435 |
0.401 |
|
2018 |
Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, ... ... Kupfer GM, et al. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. PMID 29995861 DOI: 10.1038/S41586-018-0326-5 |
0.342 |
|
2018 |
Liang Z, Teng Y, Liu J, Longerich S, Chen X, Green AM, Collins N, Lan L, Sung P, Kupfer GM. FANCI-FANCD2 Binds RNA, Which Stimulates Its Monoubiquitination Blood. 132: 645-645. DOI: 10.1182/Blood-2018-99-118863 |
0.396 |
|
2017 |
Zhao W, Steinfeld JB, Liang F, Chen X, Maranon DG, Jian Ma C, Kwon Y, Rao T, Wang W, Sheng C, Song X, Deng Y, Jimenez-Sainz J, Lu L, Jensen RB, ... ... Kupfer GM, et al. BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing. Nature. PMID 28976962 DOI: 10.1038/Nature24060 |
0.457 |
|
2016 |
Liang F, Longerich S, Miller AS, Tang C, Buzovetsky O, Xiong Y, Maranon DG, Wiese C, Kupfer GM, Sung P. Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex. Cell Reports. PMID 27239033 DOI: 10.1016/J.Celrep.2016.05.007 |
0.441 |
|
2016 |
Liang F, Longerich S, Tang C, Buzovestsky O, Xiong Y, Maranon D, Wiese C, Miller A, Sung P, Kupfer GM. The Role of UAF1 in the Fanconi Anemia Pathway Regulation of Homologous Recombination-Mediated Genome Maintenance Blood. 128: 1041-1041. DOI: 10.1182/Blood.V128.22.1041.1041 |
0.303 |
|
2015 |
Chen X, Bosques L, Sung P, Kupfer GM. A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damage. Oncogene. PMID 25893307 DOI: 10.1038/Onc.2015.68 |
0.494 |
|
2015 |
Kupfer G. Fanconi Anemia Pathway Suppression of R Loops Is a Mechanism of Maintenance of Genomic Stability Blood. 126: 1216-1216. DOI: 10.1182/Blood.V126.23.1216.1216 |
0.442 |
|
2015 |
Ducas VC, Kupfer GM. Abstract LB-C11: HTLV-1 Tax-induced apoptosis to counteract tumor drug resistance Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Lb-C11 |
0.363 |
|
2014 |
Longerich S, Li J, Xiong Y, Sung P, Kupfer GM. Stress and DNA repair biology of the Fanconi anemia pathway. Blood. 124: 2812-9. PMID 25237197 DOI: 10.1182/Blood-2014-04-526293 |
0.444 |
|
2014 |
Chen X, Wilson JB, McChesney P, Williams SA, Kwon Y, Longerich S, Marriott AS, Sung P, Jones NJ, Kupfer GM. The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization. The Journal of Biological Chemistry. 289: 25774-82. PMID 25070891 DOI: 10.1074/Jbc.M114.552570 |
0.41 |
|
2014 |
Longerich S, Kwon Y, Tsai MS, Hlaing AS, Kupfer GM, Sung P. Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA. Nucleic Acids Research. 42: 5657-70. PMID 24623813 DOI: 10.1093/Nar/Gku198 |
0.438 |
|
2014 |
Semmes OJ, Guo X, Mihaylova VT, Kupfer GM. Activation of CDK4 by Tax chemosensitizes p53-mutant cells to DNA damage Retrovirology. 11. DOI: 10.1186/1742-4690-11-S1-O44 |
0.399 |
|
2014 |
Bosques L, Tang C, Krause D, Weissman SM, Gallagher PG, Weiss MJ, Tamary H, Kupfer GM. Codanin-1 Binds to Key Erythroid Genes and Its Knockdown Coupled with Ectopic Mutant Expression Recapitulates the Congenital Dyserythropoietic Anemia Type I (CDA I) Phenotype Blood. 124: 360-360. DOI: 10.1182/Blood.V124.21.360.360 |
0.411 |
|
2013 |
Kupfer GM. Fanconi anemia: a signal transduction and DNA repair pathway. The Yale Journal of Biology and Medicine. 86: 491-7. PMID 24348213 |
0.319 |
|
2012 |
Lo SM, Choi M, Liu J, Jain D, Boot RG, Kallemeijn WW, Aerts JM, Pashankar F, Kupfer GM, Mane S, Lifton RP, Mistry PK. Phenotype diversity in type 1 Gaucher disease: discovering the genetic basis of Gaucher disease/hematologic malignancy phenotype by individual genome analysis. Blood. 119: 4731-40. PMID 22493294 DOI: 10.1182/Blood-2011-10-386862 |
0.318 |
|
2012 |
Shemer OS, Yao Y, Kupfer GM, Tamary H, Weiss MJ. Modeling Congenital Dyserythropoietic Anemia Type I Through Patient-Derived Induced Pluripotent Stem Cells Blood. 120: 3196-3196. DOI: 10.1182/Blood.V120.21.3196.3196 |
0.321 |
|
2012 |
Kupfer GM, Chen X. Regulation of PCNA Mono-Ubiqutination by FANCD2 and Rad51 in Response to Hydroxyurea. Blood. 120: 2377-2377. DOI: 10.1182/Blood.V120.21.2377.2377 |
0.414 |
|
2011 |
Williams SA, Wilson JB, Clark AP, Mitson-Salazar A, Tomashevski A, Ananth S, Glazer PM, Semmes OJ, Bale AE, Jones NJ, Kupfer GM. Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Human Molecular Genetics. 20: 4395-410. PMID 21865299 DOI: 10.1182/Blood.V116.21.3370.3370 |
0.469 |
|
2011 |
Williams SA, Longerich S, Sung P, Vaziri C, Kupfer GM. The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI. Blood. 117: 5078-87. PMID 21355096 DOI: 10.1182/Blood-2010-10-311761 |
0.454 |
|
2011 |
Green AM, Wilson JB, Jones NJ, Kupfer GM. A Role for Splicing Factors and the Transcriptional Machinery in the Pathophysiology of Fanconi Anemia Blood. 118: 3443-3443. DOI: 10.1182/Blood.V118.21.3443.3443 |
0.474 |
|
2010 |
Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM, Vaziri C. Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. The Journal of Biological Chemistry. 285: 31525-36. PMID 20675655 DOI: 10.1074/Jbc.M110.138206 |
0.473 |
|
2010 |
Zhi G, Chen X, Newcomb W, Brown J, Semmes OJ, Kupfer GM. Purification of FANCD2 sub-complexes. British Journal of Haematology. 150: 88-92. PMID 20456353 DOI: 10.1111/j.1365-2141.2010.08217.x |
0.314 |
|
2010 |
Wilson JB, Blom E, Cunningham R, Xiao Y, Kupfer GM, Jones NJ. Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance. Mutation Research. 689: 12-20. PMID 20450923 DOI: 10.1016/J.Mrfmmm.2010.04.003 |
0.342 |
|
2010 |
Green AM, Collins N, Longerich S, Sung P, Kupfer GM. A Role for Splicing Factors and R-Loop Formation in the Pathophysiology of Fanconi Anemia. Blood. 116: 3371-3371. DOI: 10.1182/Blood.V116.21.3371.3371 |
0.407 |
|
2009 |
Zhi G, Wilson JB, Chen X, Krause DS, Xiao Y, Jones NJ, Kupfer GM. Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction. Cancer Research. 69: 8775-83. PMID 19861535 DOI: 10.1158/0008-5472.Can-09-2312 |
0.428 |
|
2009 |
Noy-Lotan S, Dgany O, Lahmi R, Marcoux N, Krasnov T, Yissachar N, Ginsberg D, Motro B, Resnitzky P, Yaniv I, Kupfer GM, Tamary H. Codanin-1, the protein encoded by the gene mutated in congenital dyserythropoietic anemia type I (CDAN1), is cell cycle-regulated Haematologica. 94: 629-637. PMID 19336738 DOI: 10.3324/Haematol.2008.003327 |
0.405 |
|
2009 |
Collins NB, Wilson JB, Bush T, Thomashevski A, Roberts KJ, Jones NJ, Kupfer GM. ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function. Blood. 113: 2181-90. PMID 19109555 DOI: 10.1182/Blood-2008-05-154294 |
0.409 |
|
2009 |
Williams SA, Wilson JB, Thomashevski A, Jones NJ, Kupfer G. A Role for Mismatch Repair Factors in the FA-BRCA Pathway. Blood. 114: 1095-1095. DOI: 10.1182/Blood.V114.22.1095.1095 |
0.446 |
|
2008 |
Durkin SS, Guo X, Fryrear KA, Mihaylova VT, Gupta SK, Belgnaoui SM, Haoudi A, Kupfer GM, Semmes OJ. HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase. The Journal of Biological Chemistry. 283: 36311-20. PMID 18957425 DOI: 10.1074/Jbc.M804931200 |
0.465 |
|
2008 |
Mihaylova VT, Green AM, Khurgel M, Semmes OJ, Kupfer GM. Human T-cell leukemia virus I tax protein sensitizes p53-mutant cells to DNA damage. Cancer Research. 68: 4843-52. PMID 18559532 DOI: 10.1158/0008-5472.Can-07-5070 |
0.42 |
|
2008 |
Wilson JB, Yamamoto K, Marriott AS, Hussain S, Sung P, Hoatlin ME, Mathew CG, Takata M, Thompson LH, Kupfer GM, Jones NJ. FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3. Oncogene. 27: 3641-52. PMID 18212739 DOI: 10.1038/Sj.Onc.1211034 |
0.434 |
|
2006 |
Machida YJ, Machida Y, Chen Y, Gurtan AM, Kupfer GM, D'Andrea AD, Dutta A. UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Molecular Cell. 23: 589-96. PMID 16916645 DOI: 10.1016/J.Molcel.2006.06.024 |
0.306 |
|
2006 |
Hussain S, Wilson JB, Blom E, Thompson LH, Sung P, Gordon SM, Kupfer GM, Joenje H, Mathew CG, Jones NJ. Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2. Dna Repair. 5: 629-40. PMID 16621732 DOI: 10.1016/J.Dnarep.2006.02.007 |
0.325 |
|
2005 |
Collins N, Kupfer GM. Molecular pathogenesis of Fanconi anemia. International Journal of Hematology. 82: 176-83. PMID 16207587 DOI: 10.1532/IJH97.05108 |
0.301 |
|
2004 |
Mi J, Qiao F, Wilson JB, High AA, Schroeder MJ, Stukenberg PT, Moss A, Shabanowitz J, Hunt DF, Jones NJ, Kupfer GM. FANCG is phosphorylated at serines 383 and 387 during mitosis. Molecular and Cellular Biology. 24: 8576-85. PMID 15367677 DOI: 10.1128/Mcb.24.19.8576-8585.2004 |
0.357 |
|
2004 |
Qiao F, Mi J, Wilson JB, Zhi G, Bucheimer NR, Jones NJ, Kupfer GM. Phosphorylation of fanconi anemia (FA) complementation group G protein, FANCG, at serine 7 is important for function of the FA pathway. The Journal of Biological Chemistry. 279: 46035-45. PMID 15299017 DOI: 10.1074/Jbc.M408323200 |
0.409 |
|
2003 |
Haoudi A, Daniels RC, Wong E, Kupfer G, Semmes OJ. Human T-cell leukemia virus-I tax oncoprotein functionally targets a subnuclear complex involved in cellular DNA damage-response. The Journal of Biological Chemistry. 278: 37736-44. PMID 12842897 DOI: 10.1074/jbc.M301649200 |
0.371 |
|
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