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Ralph Brinster - Publications

Affiliations: 
Animal Biology University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, United States 
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153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Brinster RL. The lactate dehydrogenase in preimplantation mouse embryos of quackenbush and swiss mice. Febs Letters. 17: 41-44. PMID 11945992 DOI: 10.1016/0014-5793(71)80559-8  0.341
2011 Wu X, Goodyear SM, Tobias JW, Avarbock MR, Brinster RL. Spermatogonial stem cell self-renewal requires ETV5-mediated downstream activation of Brachyury in mice. Biology of Reproduction. 85: 1114-23. PMID 21816850 DOI: 10.1095/Biolreprod.111.091793  0.356
2009 Wu X, Schmidt JA, Avarbock MR, Tobias JW, Carlson CA, Kolon TF, Ginsberg JP, Brinster RL. Prepubertal human spermatogonia and mouse gonocytes share conserved gene expression of germline stem cell regulatory molecules. Proceedings of the National Academy of Sciences of the United States of America. 106: 21672-7. PMID 20018717 DOI: 10.1073/pnas.0912432106  0.384
2001 Nagano M, Brinster CJ, Orwig KE, Ryu BY, Avarbock MR, Brinster RL. Transgenic mice produced by retroviral transduction of male germ-line stem cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 13090-5. PMID 11606778 DOI: 10.1073/pnas.231473498  0.349
2000 Nagano M, Shinohara T, Avarbock MR, Brinster RL. Retrovirus-mediated gene delivery into male germ line stem cells. Febs Letters. 475: 7-10. PMID 10854847 DOI: 10.1016/S0014-5793(00)01606-9  0.305
1998 Quaife CJ, Kelly EJ, Masters BA, Brinster RL, Palmiter RD. Ectopic expression of metallothionein-III causes pancreatic acinar cell necrosis in transgenic mice. Toxicology and Applied Pharmacology. 148: 148-57. PMID 9465274 DOI: 10.1006/Taap.1997.8321  0.57
1997 Kelly EJ, Sandgren EP, Brinster RL, Palmiter RD. A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. Proceedings of the National Academy of Sciences of the United States of America. 94: 10045-50. PMID 9294160 DOI: 10.1073/Pnas.94.19.10045  0.563
1995 Rhim JA, Sandgren EP, Palmiter RD, Brinster RL. Complete reconstitution of mouse liver with xenogeneic hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 92: 4942-6. PMID 7761429 DOI: 10.1073/PNAS.92.11.4942  0.51
1995 Rhim JA, Connor W, Dixon GH, Harendza CJ, Evenson DP, Palmiter RD, Brinster RL. Expression of an avian protamine in transgenic mice disrupts chromatin structure in spermatozoa. Biology of Reproduction. 52: 20-32. PMID 7711180 DOI: 10.1095/Biolreprod52.1.20  0.595
1995 Erickson JC, Masters BA, Kelly EJ, Brinster RL, Palmiter RD. Expression of human metallothionein-III in transgenic mice. Neurochemistry International. 27: 35-41. PMID 7655346 DOI: 10.1016/0197-0186(94)00166-R  0.507
1994 Masters BA, Kelly EJ, Quaife CJ, Brinster RL, Palmiter RD. Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proceedings of the National Academy of Sciences of the United States of America. 91: 584-8. PMID 8290567 DOI: 10.1073/Pnas.91.2.584  0.585
1994 Rhim JA, Sandgren EP, Degen JL, Palmiter RD, Brinster RL. Replacement of diseased mouse liver by hepatic cell transplantation. Science (New York, N.Y.). 263: 1149-52. PMID 8108734 DOI: 10.1126/Science.8108734  0.42
1994 Quaife CJ, Hoyle GW, Froelick GJ, Findley SD, Baetge EE, Behringer RR, Hammang JP, Brinster RL, Palmiter RD. Visualization and ablation of phenylethanolamine N-methyltransferase producing cells in transgenic mice. Transgenic Research. 3: 388-400. PMID 8000434 DOI: 10.1007/Bf01976770  0.712
1994 Bamber BA, Masters BA, Hoyle GW, Brinster RL, Palmiter RD. Leukemia inhibitory factor induces neurotransmitter switching in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 7839-43. PMID 7914698 DOI: 10.1073/pnas.91.17.7839  0.477
1994 Masters B, Quaife C, Erickson J, Kelly E, Froelick G, Zambrowicz B, Brinster R, Palmiter R. Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles The Journal of Neuroscience. 14: 5844-5857. DOI: 10.1523/Jneurosci.14-10-05844.1994  0.463
1994 Messing A, Behringer R, Wrabetz L, Hammang J, Lemke G, Palmiter R, Brinster R. Hypomyelinating peripheral neuropathies and schwannomas in transgenic mice expressing SV40 T-antigen The Journal of Neuroscience. 14: 3533-3539. DOI: 10.1523/Jneurosci.14-06-03533.1994  0.682
1994 Hoyle G, Mercer E, Palmiter R, Brinster R. Cell-specific expression from the human dopamine beta-hydroxylase promoter in transgenic mice is controlled via a combination of positive and negative regulatory elements The Journal of Neuroscience. 14: 2455-2463. DOI: 10.1523/JNEUROSCI.14-05-02455.1994  0.538
1993 Sandgren EP, Luetteke NC, Qiu TH, Palmiter RD, Brinster RL, Lee DC. Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver. Molecular and Cellular Biology. 13: 320-30. PMID 8417334 DOI: 10.1128/MCB.13.1.320  0.456
1993 Zambrowicz BP, Harendza CJ, Zimmermann JW, Brinster RL, Palmiter RD. Analysis of the mouse protamine 1 promoter in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 5071-5. PMID 8389466 DOI: 10.1073/Pnas.90.11.5071  0.604
1993 Carson MJ, Behringer RR, Brinster RL, McMorris FA. Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron. 10: 729-40. PMID 8386530 DOI: 10.1016/0896-6273(93)90173-O  0.472
1993 Cullen JM, Sandgren EP, Brinster RL, Maronpot RR. Histologic characterization of hepatic carcinogenesis in transgenic mice expressing SV40 T-antigens. Veterinary Pathology. 30: 111-8. PMID 8385835 DOI: 10.1177/030098589303000203  0.33
1993 Palmiter RD, Sandgren EP, Koeller DM, Brinster RL. Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice. Molecular and Cellular Biology. 13: 5266-75. PMID 8355681 DOI: 10.1128/MCB.13.9.5266  0.602
1993 Hoyle GW, Mercer EH, Palmiter RD, Brinster RL. Expression of NGF in sympathetic neurons leads to excessive axon outgrowth from ganglia but decreased terminal innervation within tissues. Neuron. 10: 1019-34. PMID 8318227 DOI: 10.1016/0896-6273(93)90051-R  0.439
1993 Theisen M, Behringer RR, Cadd GG, Brinster RL, McKnight GS. A C/EBP-binding site in the transferrin promoter is essential for expression in the liver but not the brain of transgenic mice. Molecular and Cellular Biology. 13: 7666-76. PMID 8246983 DOI: 10.1128/MCB.13.12.7666  0.509
1993 Storb U, Engler P, Klotz E, Weng A, Haasch D, Pinkert C, Doglio L, Glymour M, Brinster R. Rearrangement and expression of immunoglobulin genes in transgenic mice. Current Topics in Microbiology and Immunology. 182: 137-41. PMID 1490348 DOI: 10.1007/978-3-642-77633-5_16  0.495
1992 Cadd GG, Hoyle GW, Quaife CJ, Marck B, Matsumoto AM, Brinster RL, Palmiter RD. Alteration of neurotransmitter phenotype in noradrenergic neurons of transgenic mice. Molecular Endocrinology (Baltimore, Md.). 6: 1951-60. PMID 1480181 DOI: 10.1210/Mend.6.11.1480181  0.543
1992 Sandgren EP, Palmiter RD, Heckel JL, Brinster RL, Degen JL. DNA rearrangement causes hepatocarcinogenesis in albumin-plasminogen activator transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 89: 11523-7. PMID 1454842 DOI: 10.1073/Pnas.89.23.11523  0.542
1992 Gibson CW, Lally E, Herold RC, Decker S, Brinster RL, Sandgren EP. Odontogenic tumors in mice carrying albumin-myc and albumin-rats transgenes. Calcified Tissue International. 51: 162-7. PMID 1422956 DOI: 10.1007/BF00298506  0.317
1992 Gardner DG, Camargo MJF, Behringer RR, Brinster RL, Baxter JD, Atlas SA, Laragh JH, Deschepper CF. Atrial natriuretic peptide synthesis in atrial tumors of transgenic mice American Journal of Physiology - Endocrinology and Metabolism. 262. PMID 1373564 DOI: 10.1152/Ajpendo.1992.262.4.E524  0.49
1992 Lo D, Freedman J, Hesse S, Palmiter RD, Brinster RL, Sherman LA. Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells. European Journal of Immunology. 22: 1013-22. PMID 1348026 DOI: 10.1002/eji.1830220421  0.511
1992 Peschon JJ, Behringer RR, Cate RL, Harwood KA, Idzerda RL, Brinster RL, Palmiter RD. Directed expression of an oncogene to Sertoli cells in transgenic mice using mullerian inhibiting substance regulatory sequences. Molecular Endocrinology (Baltimore, Md.). 6: 1403-11. PMID 1331774 DOI: 10.1210/Mend.6.9.1331774  0.679
1991 Maronpot RR, Palmiter RD, Brinster RL, Sandgren EP. Pulmonary carcinogenesis in transgenic mice. Experimental Lung Research. 17: 305-20. PMID 2050033 DOI: 10.3109/01902149109064420  0.489
1991 Engler P, Haasch D, Pinkert CA, Doglio L, Glymour M, Brinster R, Storb U. A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci. Cell. 65: 939-47. PMID 2044153 DOI: 10.1016/0092-8674(91)90546-B  0.358
1991 Lo D, Pursel V, Linton PJ, Sandgren E, Behringer R, Rexroad C, Palmiter RD, Brinster RL. Expression of mouse IgA by transgenic mice, pigs and sheep. European Journal of Immunology. 21: 1001-6. PMID 2019284 DOI: 10.1002/Eji.1830210421  0.688
1991 Caterina JJ, Ryan TM, Pawlik KM, Palmiter RD, Brinster RL, Behringer RR, Townes TM. Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 88: 1626-30. PMID 2000371 DOI: 10.1073/Pnas.88.5.1626  0.666
1991 Palmiter RD, Sandgren EP, Avarbock MR, Allen DD, Brinster RL. Heterologous introns can enhance expression of transgenes in mice. Proceedings of the National Academy of Sciences of the United States of America. 88: 478-82. PMID 1988947 DOI: 10.1073/PNAS.88.2.478  0.604
1991 Sandgren EP, Quaife CJ, Paulovich AG, Palmiter RD, Brinster RL. Pancreatic tumor pathogenesis reflects the causative genetic lesion. Proceedings of the National Academy of Sciences of the United States of America. 88: 93-7. PMID 1986386 DOI: 10.1073/PNAS.88.1.93  0.484
1991 Guthrie HD, Pursel VG, Miller KF, Bolt DJ, Palmiter RD, Brinster RL. Effect of bovine growth hormone gene expression, sex and age on plasma gonadotropins, estrone and testosterone in prepuberal pigs. Domestic Animal Endocrinology. 8: 423-9. PMID 1748001 DOI: 10.1016/0739-7240(91)90010-H  0.502
1991 Kapur RP, Hoyle GW, Mercer EH, Brinster RL, Palmiter RD. Some neuronal cell populations express human dopamine beta-hydroxylase-lacZ transgenes transiently during embryonic development. Neuron. 7: 717-27. PMID 1742022 DOI: 10.1016/0896-6273(91)90275-5  0.566
1991 Mercer EH, Hoyle GW, Kapur RP, Brinster RL, Palmiter RD. The dopamine beta-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice. Neuron. 7: 703-16. PMID 1742021 DOI: 10.1016/0896-6273(91)90274-4  0.538
1991 Rexroad CE, Mayo K, Bolt DJ, Elsasser TH, Miller KF, Behringer RR, Palmiter RD, Brinster RL. Transferrin- and albumin-directed expression of growth-related peptides in transgenic sheep. Journal of Animal Science. 69: 2995-3004. PMID 1715850 DOI: 10.2527/1991.6972995X  0.556
1990 Burkly LC, Lo D, Brinster RL, Flavell RA. I-E transgenic mice: a model system to dissect the regulation and function of MHC class II genes in vivo. Immunologic Research. 9: 34-46. PMID 2406351 DOI: 10.1007/Bf02918477  0.337
1990 Behringer RR, Lewin TM, Quaife CJ, Palmiter RD, Brinster RL, D'Ercole AJ. Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice. Endocrinology. 127: 1033-40. PMID 2387246 DOI: 10.1210/Endo-127-3-1033  0.645
1990 Hammang JP, Baetge EE, Behringer RR, Brinster RL, Palmiter RD, Messing A. Immortalized retinal neurons derived from SV40 T-antigen-induced tumors in transgenic mice. Neuron. 4: 775-82. PMID 2344410 DOI: 10.1016/0896-6273(90)90204-S  0.616
1990 Lo D, Burkly LC, Flavell RA, Palmiter RD, Brinster RL. Antigen presentation in MHC class II transgenic mice: stimulation versus tolerization. Immunological Reviews. 117: 121-34. PMID 2258189 DOI: 10.1111/J.1600-065X.1990.Tb00570.X  0.473
1990 Ryan TM, Townes TM, Reilly MP, Asakura T, Palmiter RD, Brinster RL, Behringer RR. Human sickle hemoglobin in transgenic mice. Science (New York, N.Y.). 247: 566-8. PMID 2154033 DOI: 10.1126/Science.2154033  0.669
1990 Denis KA, Witte ON, Brinster RL, Provost S, Storb U. Delay of Early B-Lymphocyte Development By Gamma 2b Immunoglobulin Transgene: Effect on Differentiation- Specific Molecules Developmental Immunology. 1: 105-112. PMID 1967016 DOI: 10.1155/1990/71584  0.395
1990 Braun RE, Lo D, Pinkert CA, Widera G, Flavell RA, Palmiter RD, Brinster RL. Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells. Biology of Reproduction. 43: 684-93. PMID 1963095 DOI: 10.1095/Biolreprod43.4.684  0.623
1990 Heckel JL, Sandgren EP, Degen JL, Palmiter RD, Brinster RL. Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator. Cell. 62: 447-56. PMID 1696178 DOI: 10.1016/0092-8674(90)90010-C  0.583
1990 Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC. Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell. 61: 1121-35. PMID 1693546 DOI: 10.1016/0092-8674(90)90075-P  0.488
1990 Behringer RR, Ryan TM, Palmiter RD, Brinster RL, Townes TM. Human gamma- to beta-globin gene switching in transgenic mice. Genes & Development. 4: 380-9. PMID 1692558 DOI: 10.1101/Gad.4.3.380  0.652
1990 Moriyama T, Guilhot S, Klopchin K, Moss B, Pinkert CA, Palmiter RD, Brinster RL, Kanagawa O, Chisari FV. Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science (New York, N.Y.). 248: 361-4. PMID 1691527 DOI: 10.1126/Science.1691527  0.457
1990 BEHRINGER RR, RYAN TM, REILLY MP, ASAKURA T, PALMITER RD, BRINSTER RL, TOWNES TM. A Transgenic Mouse Model for Human Sickle Cell Disease Proceedings of the Japanese Association of Animal Models For Human Diseases. 6: 6-12. DOI: 10.1538/Expanim1985.6.6  0.588
1989 Markmann J, Lo D, Naji A, Palmiter RD, Brinster RL, Heber-Katz E. Antigen presenting function of class II MHC expressing pancreatic beta cells. Nature. 336: 476-9. PMID 3143077 DOI: 10.1038/336476A0  0.458
1989 Miller KF, Bolt DJ, Pursel VG, Hammer RE, Pinkert CA, Palmiter RD, Brinster RL. Expression of human or bovine growth hormone gene with a mouse metallothionein-1 promoter in transgenic swine alters the secretion of porcine growth hormone and insulin-like growth factor-I Journal of Endocrinology. 120: 481-488. PMID 2926315 DOI: 10.1677/Joe.0.1200481  0.552
1989 Ryan TM, Behringer RR, Townes TM, Palmiter RD, Brinster RL. High-level erythroid expression of human α-globin genes in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 86: 37-41. PMID 2911581 DOI: 10.1073/Pnas.86.1.37  0.652
1989 Braun RE, Behringer RR, Peschon JJ, Brinster RL, Palmiter RD. Genetically haploid spermatids are phenotypically diploid. Nature. 337: 373-6. PMID 2911388 DOI: 10.1038/337373A0  0.634
1989 Brinster RL, Sandgren EP, Behringer RR, Palmiter RD. No simple solution for making transgenic mice. Cell. 59: 239-41. PMID 2805065 DOI: 10.1016/0092-8674(89)90282-1  0.594
1989 Peschon JJ, Behringer RR, Palmiter RD, Brinster RL. Expression of mouse protamine 1 genes in transgenic mice. Annals of the New York Academy of Sciences. 564: 186-97. PMID 2774416 DOI: 10.1111/J.1749-6632.1989.Tb25897.X  0.703
1989 Behringer RR, Ryan TM, Reilly MP, Asakura T, Palmiter RD, Brinster RL, Townes TM. Synthesis of functional human hemoglobin in transgenic mice. Science (New York, N.Y.). 245: 971-3. PMID 2772649 DOI: 10.1126/Science.2772649  0.664
1989 Braun RE, Peschon JJ, Behringer RR, Brinster RL, Palmiter RD. Protamine 3'-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice. Genes & Development. 3: 793-802. PMID 2744463 DOI: 10.1101/Gad.3.6.793  0.664
1989 Ryan TM, Behringer RR, Martin NC, Townes TM, Palmiter RD, Brinster RL. A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice Genes &Amp; Development. 3: 314-323. PMID 2721958 DOI: 10.1101/gad.3.3.314  0.629
1989 Quaife CJ, Mathews LS, Pinkert CA, Hammer RE, Brinster RL, Palmiter RD. Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice. Endocrinology. 124: 40-8. PMID 2642417 DOI: 10.1210/Endo-124-1-40  0.504
1989 Idzerda RL, Behringer RR, Theisen M, Huggenvik JI, McKnight GS, Brinster RL. Expression from the transferrin gene promoter in transgenic mice Molecular and Cellular Biology. 9: 5154-5162. PMID 2601714 DOI: 10.1128/Mcb.9.11.5154  0.632
1989 Wolgemuth DJ, Behringer RR, Mostoller MP, Brinster RL, Palmiter RD. Transgenic mice overexpressing the mouse homoeobox-containing gene Hox-1.4 exhibit abnormal gut development. Nature. 337: 464-7. PMID 2563568 DOI: 10.1038/337464A0  0.706
1989 Lo D, Burkly LC, Flavell RA, Palmiter RD, Brinster RL. Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells. The Journal of Experimental Medicine. 170: 87-104. PMID 2526197 DOI: 10.1084/Jem.170.1.87  0.548
1989 Rexroad CE, Hammer RE, Bolt DJ, Mayo KE, Frohman LA, Palmitter RD, Brinster RL. Production of transgenic sheep with growth-regulating genes Molecular Reproduction and Development. 1: 164-169. PMID 2516725 DOI: 10.1002/Mrd.1080010304  0.382
1989 Brinster RL, Braun RE, Lo D, Avarbock MR, Oram F, Palmiter RD. Targeted correction of a major histocompatibility class II E alpha gene by DNA microinjected into mouse eggs. Proceedings of the National Academy of Sciences of the United States of America. 86: 7087-91. PMID 2506546 DOI: 10.1073/Pnas.86.18.7087  0.496
1989 Brar AK, Brinster RL, Frohman LA. Immunohistochemical analysis of human growth hormone-releasing hormone gene expression in transgenic mice. Endocrinology. 125: 801-9. PMID 2502376 DOI: 10.1210/ENDO-125-2-801  0.406
1989 Pursel VG, Pinkert CA, Miller KF, Bolt DJ, Campbell RG, Palmiter RD, Brinster RL, Hammer RE. Genetic engineering of livestock. Science (New York, N.Y.). 244: 1281-8. PMID 2499927 DOI: 10.1126/Science.2499927  0.489
1989 Hagman J, Lo D, Doglio LT, Hackett J, Rudin CM, Haasch D, Brinster R, Storb U. Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene. The Journal of Experimental Medicine. 169: 1911-29. PMID 2499652 DOI: 10.1084/Jem.169.6.1911  0.494
1989 Messing A, Behrinqer RR, Hammang JP, Lemke G, Brinster RL, Palmiter RD. SCHWANN-CEIL-SPECIFIC GENE EXPRESSION IN TRANSGENIC MICE Journal of Neuropathology and Experimental Neurology. 48: 347. DOI: 10.1097/00005072-198905000-00144  0.639
1988 Brinster RL, Allen JM, Behringer RR, Gelinas RE, Palmiter RD. Introns increase transcriptional efficiency in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 85: 836-40. PMID 3422466 DOI: 10.1073/Pnas.85.3.836  0.701
1988 Mathews LS, Hammer RE, Brinster RL, Palmiter RD. Expression of insulin-like growth factor I in transgenic mice with elevated levels of growth hormone is correlated with growth. Endocrinology. 123: 433-7. PMID 3383777 DOI: 10.1210/endo-123-1-433  0.534
1988 Behringer RR, Mathews LS, Palmiter RD, Brinster RL. Dwarf mice produced by genetic ablation of growth hormone-expressing cells. Genes & Development. 2: 453-61. PMID 3286373 DOI: 10.1101/Gad.2.4.453  0.709
1988 Paul D, Höhne M, Pinkert C, Piasecki A, Ummelmann E, Brinster RL. Immortalized differentiated hepatocyte lines derived from transgenic mice harboring SV40 T-antigen genes. Experimental Cell Research. 175: 354-62. PMID 3282899 DOI: 10.1016/0014-4827(88)90199-1  0.421
1988 Marrack P, Lo D, Brinster R, Palmiter R, Burkly L, Flavell RH, Kappler J. The effect of thymus environment on T cell development and tolerance. Cell. 53: 627-34. PMID 3259471 DOI: 10.1016/0092-8674(88)90578-8  0.489
1988 Mathews LS, Hammer RE, Behringer RR, D'Ercole AJ, Bell GI, Brinster RL, Palmiter RD. Growth enhancement of transgenic mice expressing human insulin-like growth factor I. Endocrinology. 123: 2827-33. PMID 3197646 DOI: 10.1210/endo-123-6-2827  0.643
1988 Manz J, Denis K, Witte O, Brinster R, Storb U. Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains. The Journal of Experimental Medicine. 168: 1363-81. PMID 3139821 DOI: 10.1084/Jem.168.4.1363  0.443
1988 Mayo KE, Hammer RE, Swanson LW, Brinster RL, Rosenfeld MG, Evans RM. Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone-releasing factor gene. Molecular Endocrinology (Baltimore, Md.). 2: 606-12. PMID 3137455 DOI: 10.1210/Mend-2-7-606  0.475
1988 Storb U, Engler P, Manz J, Gollahon K, Denis K, Lo D, Brinster R. Expression of immunoglobulin genes in transgenic mice and transfected cells. Annals of the New York Academy of Sciences. 546: 51-6. PMID 3073699 DOI: 10.1111/J.1749-6632.1988.Tb21618.X  0.455
1988 Lo D, Burkly LC, Widera G, Cowing C, Flavell RA, Palmiter RD, Brinster RL. Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell. 53: 159-68. PMID 2964908 DOI: 10.1016/0092-8674(88)90497-7  0.503
1988 Baetge EE, Behringer RR, Messing A, Brinster RL, Palmiter RD. Transgenic mice express the human phenylethanolamine N-methyltransferase gene in adrenal medulla and retina. Proceedings of the National Academy of Sciences of the United States of America. 85: 3648-52. PMID 2835776 DOI: 10.1073/Pnas.85.10.3648  0.696
1988 Behringer RR, Peschon JJ, Messing A, Gartside CL, Hauschka SD, Palmiter RD, Brinster RL. Heart and bone tumors in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 85: 2648-52. PMID 2833748 DOI: 10.1073/Pnas.85.8.2648  0.643
1987 Ornitz DM, Hammer RE, Davison BL, Brinster RL, Palmiter RD. Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers Molecular and Cellular Biology. 7: 3466-3472. PMID 3683390 DOI: 10.1128/Mcb.7.10.3466  0.59
1987 Pinkert CA, Ornitz DM, Brinster RL, Palmiter RD. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice Genes &Amp; Development. 1: 268-276. PMID 3678824 DOI: 10.1101/Gad.1.3.268  0.59
1987 Hammer RE, Swift GH, Ornitz DM, Quaife CJ, Palmiter RD, Brinster RL, MacDonald RJ. The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice Molecular and Cellular Biology. 7: 2956-2967. PMID 3670302 DOI: 10.1128/Mcb.7.8.2956  0.604
1987 Palmiter RD, Behringer RR, Quaife CJ, Maxwell F, Maxwell IH, Brinster RL. Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell. 50: 435-43. PMID 3649277 DOI: 10.1016/0092-8674(87)90497-1  0.708
1987 MacDonald RJ, Hammer RE, Swift GH, Davis BP, Brinster RL. Transgenic progeny inherit tissue-specific expression of rat elastase I genes. Dna (Mary Ann Liebert, Inc.). 5: 393-401. PMID 3640697 DOI: 10.1089/dna.1986.5.393  0.358
1987 Palmiter RD, Brinster RL. Germ-line transformation of mice. Annual Review of Genetics. 20: 465-99. PMID 3545063 DOI: 10.1146/annurev.ge.20.120186.002341  0.494
1987 Cory S, Harris AW, Langdon WY, Alexander WS, Corcoran LM, Palmiter RD, Pinkert CA, Brinster RL, Adams JM. The myc oncogene and lymphoid neoplasia: from translocations to transgenic mice. Haematology and Blood Transfusion. 31: 248-51. PMID 3502109 DOI: 10.1007/978-3-642-72624-8_51  0.511
1987 Pursel VG, Rexroad CE, Bolt DJ, Miller KF, Wall RJ, Hammer RE, Pinkert CA, Palmiter RD, Brinster RL. Progress on gene transfer in farm animals Veterinary Immunology and Immunopathology. 17: 303-312. PMID 3481144 DOI: 10.1016/0165-2427(87)90149-8  0.575
1987 Behringer RR, Hammer RE, Brinster RL, Palmiter RD, Townes TM. Two 3' sequences direct adult erythroid-specific expression of human β-globulin genes in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 84: 7056-7060. PMID 3478680 DOI: 10.1073/Pnas.84.20.7056  0.641
1987 Chisari FV, Filippi P, Buras J, McLachlan A, Popper H, Pinkert CA, Palmiter RD, Brinster RL. Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 84: 6909-13. PMID 3477814 DOI: 10.1073/Pnas.84.19.6909  0.455
1987 Quaife CJ, Pinkert CA, Ornitz DM, Palmiter RD, Brinster RL. Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice Cell. 48: 1023-1034. PMID 3470144 DOI: 10.1016/0092-8674(87)90710-0  0.535
1987 MacDonald RJ, Swift GH, Hammer RE, Ornitz DM, Davis BP, Brinster RL, Palmiter RD. Chapter 1 Targeted expression of cloned genes in transgenic mice Progress in Brain Research. 71: 3-12. PMID 3295992 DOI: 10.1016/S0079-6123(08)61809-9  0.59
1987 Palmiter RD, Brinster RL. Gene transplants into germ cells. Hospital Practice (Office Ed.). 22: 77-83, 87-8. PMID 3040788 DOI: 10.1080/21548331.1987.11703306  0.454
1987 Peschon JJ, Behringer RR, Brinster RL, Palmiter RD. Spermatid-specific expression of protamine 1 in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 84: 5316-9. PMID 3037541 DOI: 10.1073/pnas.84.15.5316  0.714
1987 MacKay K, Striker LJ, Pinkert CA, Brinster RL, Striker GE. Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40 Kidney International. 32: 827-837. PMID 2828752 DOI: 10.1038/Ki.1987.283  0.332
1987 Ornitz DM, Hammer RE, Messing A, Palmiter RD, Brinster RL. Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. Science (New York, N.Y.). 238: 188-93. PMID 2821617 DOI: 10.1126/Science.2821617  0.525
1987 Pinkert CA, Brinster RL, Palmiter RD, Wong C, Butel JS. Tumorigenesis in transgenic mice by a nuclear transport-defective SV40 large T-antigen gene. Virology. 160: 169-75. PMID 2820126 DOI: 10.1016/0042-6822(87)90057-2  0.512
1987 Goldman MA, Stokes KR, Idzerda RL, McKnight GS, Hammer RE, Brinster RL, Gartler SM. A chicken transferrin gene in transgenic mice escapes X-chromosome inactivation. Science (New York, N.Y.). 236: 593-5. PMID 2437652 DOI: 10.1126/Science.2437652  0.417
1987 Hammer RE, Krumlauf R, Camper SA, Brinster RL, Tilghman SM. Diversity of Alpha-Fetoprotein gene expression in mice is generated by a combination of separate enhancer elements Science. 235: 53-58. PMID 2432657 DOI: 10.1126/Science.2432657  0.391
1987 Messing A, Pinkert CA, Palmiter RD, Brinster RL. DEVELOPMENTAL STUDY OF SV*** GENE EXPRESSION IN TRANSGENIC MICE WITH DISORDERS OF CHOROID PLEXUS, THYMUS AND KIDNEY Journal of Neuropathology and Experimental Neurology. 46: 373. DOI: 10.1097/00005072-198705000-00132  0.588
1986 Hammer RE, Idzerda RL, Brinster RL, McKnight GS. Estrogen regulation of the avian transferrin gene in transgenic mice Molecular and Cellular Biology. 6: 1010-1014. PMID 3785157  0.439
1986 Chisari FV, Filippi P, McLachlan A, Milich DR, Riggs M, Lee S, Palmiter RD, Pinkert CA, Brinster RL. Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice. Journal of Virology. 60: 880-7. PMID 3783819 DOI: 10.1128/Jvi.60.3.880-887.1986  0.431
1986 Wilkie TM, Brinster RL, Palmiter RD. Germline and somatic mosaicism in transgenic mice. Developmental Biology. 118: 9-18. PMID 3770310 DOI: 10.1016/0012-1606(86)90068-0  0.539
1986 MacDonald RJ, Hammer RE, Swift GH, Ornitz DM, Davis BP, Palmiter RD, Brinster RL. Tissue-specific expression of pancreatic genes in transgenic mice Annals of the New York Academy of Sciences. 478: 131-146. PMID 3541749 DOI: 10.1111/J.1749-6632.1986.Tb15527.X  0.612
1986 Adams JM, Harris AW, Langdon WY, Pinkert CA, Brinster RL, Palmiter RD, Corcoran L, Alexander WS, Graham MW, Cory S. c-myc-induced lymphomagenesis in transgenic mice and the role of the Pvt-1 locus in lymphoid neoplasia. Current Topics in Microbiology and Immunology. 132: 1-8. PMID 3491731 DOI: 10.1007/978-3-642-71562-4_1  0.452
1986 Hammer RE, Pursel VG, Rexroad CE, Wall RJ, Bolt DJ, Palmiter RD, Brinster RL. Genetic engineering of mammalian embryos. Journal of Animal Science. 63: 269-78. PMID 3460980 DOI: 10.2527/jas1986.631269x  0.527
1986 Storb U, Ritchie KA, O'Brien R, Arp B, Brinster R. Expression, allelic exclusion and somatic mutation of mouse immunoglobulin kappa genes. Immunological Reviews. 89: 85-102. PMID 3081435 DOI: 10.1111/J.1600-065X.1986.Tb01474.X  0.41
1986 Hammer RE, Brinster RL, Palmiter RD. Use of gene transfer to increase animal growth. Cold Spring Harbor Symposia On Quantitative Biology. 50: 379-87. PMID 3006997 DOI: 10.1101/SQB.1985.050.01.048  0.464
1986 Low MJ, Lechan RM, Hammer RE, Brinster RL, Habener JF, Mandel G, Goodman RH. Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice. Science (New York, N.Y.). 231: 1002-4. PMID 2868526 DOI: 10.1126/Science.2868526  0.486
1986 Storb U, Pinkert C, Arp B, Engler P, Gollahon K, Manz J, Brady W, Brinster RL. Transgenic mice with mu and kappa genes encoding antiphosphorylcholine antibodies. The Journal of Experimental Medicine. 164: 627-41. PMID 2425036 DOI: 10.1084/Jem.164.2.627  0.436
1986 Krumlauf R, Chapman VM, Hammer RE, Brinster R, Tilghman SM. Differential expression of alpha-fetoprotein genes on the inactive X chromosome in extraembryonic and somatic tissues of a transgenic mouse line. Nature. 319: 224-6. PMID 2418359 DOI: 10.1038/319224A0  0.386
1985 Palmiter RD, Hammer RE, Brinster RL. Expression of Growth Hormone Genes in Transgenic Mice. Banbury Report. 20: 123-132. PMID 27358506  0.661
1985 Ritchie KA, Brinster RL, Storb U. Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice. Nature. 312: 517-20. PMID 6438533 DOI: 10.1038/312517A0  0.446
1985 Brinster RL, Palmiter RD. Transgenic mice containing growth hormone fusion genes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 309-12. PMID 6151702 DOI: 10.1098/rstb.1984.0132  0.629
1985 Swanson LW, Simmons DM, Arriza J, Hammer R, Brinster R, Rosenfeld MG, Evans RM. Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes. Nature. 317: 363-6. PMID 4047165 DOI: 10.1038/317363A0  0.58
1985 Storb U, Denis KA, Brinster RL, Witte ON. Pre-B cells in κ-transgenic mice Nature. 316: 356-358. PMID 3927171 DOI: 10.1038/316356A0  0.441
1985 Hammer RE, Brinster RL, Rosenfeld MG, Evans RM, Mayo KE. Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth Nature. 315: 413-416. PMID 3923368 DOI: 10.1038/315413a0  0.387
1985 Adams JM, Harris AW, Pinkert CA, Corcoran LM, Alexander WS, Cory S, Palmiter RD, Brinster RL. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature. 318: 533-8. PMID 3906410 DOI: 10.1038/318533A0  0.537
1985 Brinster RL, Chen HY, Trumbauer ME, Yagle MK, Palmiter RD. Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proceedings of the National Academy of Sciences of the United States of America. 82: 4438-42. PMID 3892534 DOI: 10.1073/pnas.82.13.4438  0.55
1985 Hammer RE, Pursel VG, Rexroad CE, Wall RJ, Bolt DJ, Ebert KM, Palmiter RD, Brinster RL. Production of transgenic rabbits, sheep and pigs by microinjection. Nature. 315: 680-3. PMID 3892305 DOI: 10.1038/315680a0  0.634
1985 Chisari FV, Pinkert CA, Milich DR, Filippi P, McLachlan A, Palmiter RD, Brinster RL. A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. Science (New York, N.Y.). 230: 1157-60. PMID 3865369 DOI: 10.1126/Science.3865369  0.52
1985 Ornitz DM, Palmiter RD, Hammer RE, Brinster RL, Swift GH, MacDonald RJ. Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice Nature. 313: 600-602. PMID 3844051 DOI: 10.1038/313600A0  0.64
1985 Townes TM, Chen HY, Lingrel JB, Palmiter RD, Brinster RL. Expression of human β-globin genes in transgenic mice: effects of a flanking metallothionein-human growth hormone fusion gene Molecular and Cellular Biology. 5: 1977-1983. PMID 3018541 DOI: 10.1128/Mcb.5.8.1977  0.604
1985 Ornitz DM, Palmiter RD, Messing A, Hammer RE, Pinkert CA, Brinster RL. Elastase I promoter directs expression of human growth hormone and SV40 T antigen genes to pancreatic acinar cells in transgenic mice. Cold Spring Harbor Symposia On Quantitative Biology. 50: 399-409. PMID 3006998 DOI: 10.1101/Sqb.1985.050.01.050  0.62
1985 Stout JT, Chen HY, Brennand J, Caskey CT, Brinster RL. Expression of human HPRT in the central nervous system of transgenic mice. Nature. 317: 250-2. PMID 2995815 DOI: 10.1038/317250a0  0.415
1985 Messing A, Chen HY, Palmiter RD, Brinster RL. Peripheral neuropathies, hepatocellular carcinomas and islet cell adenomas in transgenic mice. Nature. 316: 461-3. PMID 2991772 DOI: 10.1038/316461A0  0.613
1985 Palmiter RD, Chen HY, Messing A, Brinster RL. SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice. Nature. 316: 457-60. PMID 2991771 DOI: 10.1038/316457A0  0.566
1985 Palmiter RD, Brinster RL. Transgenic mice. Cell. 41: 343-5. PMID 2985274 DOI: 10.1016/S0092-8674(85)80004-0  0.545
1985 Low MJ, Hammer RE, Goodman RH, Habener JF, Palmiter RD, Brinster RL. Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice. Cell. 41: 211-9. PMID 2859927 DOI: 10.1016/0092-8674(85)90075-3  0.506
1985 Krumlauf R, Hammer RE, Brinster R, Chapman VM, Tilghman SM. Regulated expression of alpha-fetoprotein genes in transgenic mice. Cold Spring Harbor Symposia On Quantitative Biology. 50: 371-8. PMID 2420515 DOI: 10.1101/Sqb.1985.050.01.047  0.507
1985 Krumlauf R, Hammer RE, Tilghman SM, Brinster RL. Developmental regulation of α-fetoprotein genes in transgenic mice Molecular and Cellular Biology. 5: 1639-1648. PMID 2410773 DOI: 10.1128/MCB.5.7.1639  0.452
1985 Pinkert C, Widera G, Cowing C, Heber-Katz E, Palmiter R, Flavell R, Brinster R. Tissue-specific, inducible and functional expression of the E alpha d MHC class II gene in transgenic mice. The Embo Journal. 4: 2225-2230. DOI: 10.1002/J.1460-2075.1985.Tb03918.X  0.575
1985 Townes T, Lingrel J, Chen H, Brinster R, Palmiter R. Erythroid-specific expression of human beta-globin genes in transgenic mice. The Embo Journal. 4: 1715-1723. DOI: 10.1002/J.1460-2075.1985.Tb03841.X  0.579
1984 Swift GH, Hammer RE, MacDonald RJ, Brinster RL. Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice. Cell. 38: 639-46. PMID 6567483 DOI: 10.1016/0092-8674(84)90258-7  0.405
1984 Hammer RE, Palmiter RD, Brinster RL. Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene. Nature. 311: 65-7. PMID 6472463 DOI: 10.1038/311065a0  0.545
1984 Storb U, O'Brien RL, McMullen MD, Gollahon KA, Brinster RL. High expression of cloned immunoglobulin kappa gene in transgenic mice is restricted to B lymphocytes. Nature. 310: 238-41. PMID 6431295 DOI: 10.1038/310238A0  0.457
1984 Brinster RL, Ritchie KA, Hammer RE, O'Brien RL, Arp B, Storb U. Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice. Nature. 306: 332-6. PMID 6417544 DOI: 10.1038/306332A0  0.47
1984 Brinster RL, Chen HY, Messing A, van Dyke T, Levine AJ, Palmiter RD. Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell. 37: 367-79. PMID 6327063 DOI: 10.1016/0092-8674(84)90367-2  0.582
1984 Palmiter RD, Wilkie TM, Chen HY, Brinster RL. Transmission distortion and mosaicism in an unusual transgenic mouse pedigree. Cell. 36: 869-77. PMID 6323025 DOI: 10.1016/0092-8674(84)90036-9  0.542
1984 Durnam DM, Hoffman JS, Quaife CJ, Benditt EP, Chen HY, Brinster RL, Palmiter RD. Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones. Proceedings of the National Academy of Sciences of the United States of America. 81: 1053-6. PMID 6322185 DOI: 10.1073/Pnas.81.4.1053  0.471
1984 Stuart GW, Searle PF, Chen HY, Brinster RL, Palmiter RD. A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene Proceedings of the National Academy of Sciences of the United States of America. 81: 7318-7322. PMID 6095286 DOI: 10.1073/pnas.81.23.7318  0.494
1983 Palmiter RD, Brinster RL, Hammer RE, Trumbauer ME, Rosenfeld MG, Birnberg NC, Evans RM. Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature. 300: 611-5. PMID 6958982 DOI: 10.1038/300611a0  0.583
1983 Palmiter RD, Norstedt G, Gelinas RE, Hammer RE, Brinster RL. Metallothionein-human GH fusion genes stimulate growth of mice. Science (New York, N.Y.). 222: 809-14. PMID 6356363 DOI: 10.1126/science.6356363  0.614
1983 McKnight GS, Hammer RE, Kuenzel EA, Brinster RL. Expression of the chicken transferrin gene in transgenic mice. Cell. 34: 335-41. PMID 6311428 DOI: 10.1016/0092-8674(83)90368-9  0.472
1982 Palmiter RD, Chen HY, Brinster RL. Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring. Cell. 29: 701-10. PMID 7116454 DOI: 10.1016/0092-8674(82)90186-6  0.607
1982 Brinster RL, Chen HY, Warren R, Sarthy A, Palmiter RD. Regulation of metallothionein--thymidine kinase fusion plasmids injected into mouse eggs. Nature. 296: 39-42. PMID 6278311 DOI: 10.1038/296039a0  0.515
1982 Brinster RL, Chen HY, Trumbauer M, Senear AW, Warren R, Palmiter RD. Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell. 27: 223-31. PMID 6276022 DOI: 10.1016/0092-8674(81)90376-7  0.611
1982 Brinster R, Palmiter R. Induction of foreign genes in animals Trends in Biochemical Sciences. 7: 438-440. DOI: 10.1016/S0968-0004(82)80012-1  0.496
1981 Brinster RL, Chen HY, Trumbauer ME. Mouse oocytes transcribe injected Xenopus 5S RNA gene. Science (New York, N.Y.). 211: 396-8. PMID 7194505 DOI: 10.1126/science.7194505  0.304
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