Mikel Valle

Affiliations: 
Natl. Center of Biotechnology (CSIC) 
 CIC bioGUNE, Spain 
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"Mikel Valle"
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Lázaro M, Melero R, Huet C, et al. (2021) 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme. Communications Biology. 4: 684
Fernández-Millán P, Lázaro M, Canslz-Arda Ş, et al. (2015) The hexameric structure of the human mitochondrial replicative helicase Twinkle Nucleic Acids Research. 43: 4284-4295
Melero R, Rajagopalan S, Lázaro M, et al. (2011) Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA. Proceedings of the National Academy of Sciences of the United States of America. 108: 557-62
Scheres SHW, Melero R, Valle M, et al. (2009) Averaging of electron subtomograms and random conical tilt reconstructions through likelihood optimization. Structure (London, England : 1993). 17: 1563-1572
Scheres SH, Valle M, Grob P, et al. (2009) Maximum likelihood refinement of electron microscopy data with normalization errors. Journal of Structural Biology. 166: 234-40
Julián P, Konevega AL, Scheres SH, et al. (2008) Structure of ratcheted ribosomes with tRNAs in hybrid states. Proceedings of the National Academy of Sciences of the United States of America. 105: 16924-7
Tidow H, Melero R, Mylonas E, et al. (2007) Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex. Proceedings of the National Academy of Sciences of the United States of America. 104: 12324-9
Scheres SH, Gao H, Valle M, et al. (2007) Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization. Nature Methods. 4: 27-9
Valle M, Chen XS, Donate LE, et al. (2006) Structural basis for the cooperative assembly of large T antigen on the origin of replication. Journal of Molecular Biology. 357: 1295-305
Scheres SH, Valle M, Carazo JM. (2005) Fast maximum-likelihood refinement of electron microscopy images. Bioinformatics (Oxford, England). 21: ii243-4
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