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Ed Reznik, Ph.D. - Publications

Affiliations: 
2013 Biomedical Engineering Boston University, Boston, MA, United States 
Area:
Biomedical Engineering, Applied Mathematics
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64/121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mahmood M, Liu EM, Shergold AL, Tolla E, Tait-Mulder J, Huerta-Uribe A, Shokry E, Young AL, Lilla S, Kim M, Park T, Boscenco S, Manchon JL, Rodríguez-Antona C, Walters RC, ... ... Reznik E, et al. Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature Cancer. PMID 38286828 DOI: 10.1038/s43018-023-00721-w  0.306
2023 Benedetti E, Liu EM, Tang C, Kuo F, Buyukozkan M, Park T, Park J, Correa F, Hakimi AA, Intlekofer AM, Krumsiek J, Reznik E. A multimodal atlas of tumour metabolism reveals the architecture of gene-metabolite covariation. Nature Metabolism. PMID 37337120 DOI: 10.1038/s42255-023-00817-8  0.328
2023 Mahmood M, Liu EM, Shergold AL, Tolla E, Tait-Mulder J, Uribe AH, Shokry E, Young AL, Lilla S, Kim M, Park T, Manchon JL, Rodríguez-Antona C, Walters RC, Springett RJ, ... ... Reznik E, et al. Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade. Biorxiv : the Preprint Server For Biology. PMID 36993533 DOI: 10.1101/2023.03.21.533091  0.304
2022 Kim M, Mahmood M, Reznik E, Gammage PA. Mitochondrial DNA is a major source of driver mutations in cancer. Trends in Cancer. PMID 36041967 DOI: 10.1016/j.trecan.2022.08.001  0.311
2020 Hakimi AA, Attalla K, DiNatale RG, Ostrovnaya I, Flynn J, Blum KA, Ged Y, Hoen D, Kendall SM, Reznik E, Bowman A, Hwee J, Fong CJ, Kuo F, Voss MH, et al. A pan-cancer analysis of PBAF complex mutations and their association with immunotherapy response. Nature Communications. 11: 4168. PMID 32820162 DOI: 10.1038/S41467-020-17965-0  0.359
2020 Silagy AW, Duzgol C, Marcon J, DiNatale RG, Mano R, Blum KA, Reznik E, Voss MH, Motzer RJ, Coleman JA, Russo P, Akin O, Hakimi AA. An evaluation of the role of tumor load in cytoreductive nephrectomy. Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada. PMID 32569570 DOI: 10.5489/Cuaj.6350  0.3
2020 Gorelick AN, Sánchez-Rivera FJ, Cai Y, Bielski CM, Biederstedt E, Jonsson P, Richards AL, Vasan N, Penson AV, Friedman ND, Ho YJ, Baslan T, Bandlamudi C, Scaltriti M, Schultz N, ... ... Reznik E, et al. Phase and context shape the function of composite oncogenic mutations. Nature. PMID 32461694 DOI: 10.1038/S41586-020-2315-8  0.354
2020 Marcon J, DiNatale RG, Sanchez A, Kotecha RR, Gupta S, Kuo F, Makarov V, Sandhu A, Mano R, Silagy AW, Blum KA, Nassau DE, Benfante NE, Ortiz MV, Carlo MI, ... ... Reznik E, et al. Comprehensive genomic analysis of translocation renal cell carcinoma reveals copy number variations as drivers of disease progression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32220885 DOI: 10.1158/1078-0432.Ccr-19-3283  0.364
2020 Vasan N, Razavi P, Johnson JL, Shao H, Wilson T, Schimmoller F, Shah H, Antoine A, Ladewig E, Gorelick A, Lin T, Toska E, Xu G, Kazmi A, Chang MT, ... ... Reznik E, et al. Abstract P3-03-01: Double PIK3CA mutations in cis drive oncogene addiction and enhance sensitivity to PI3K alpha inhibitors in breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-03-01  0.357
2019 DiNatale RG, Gorelick AN, Makarov V, Blum KA, Silagy AW, Freeman B, Chowell D, Marcon J, Mano R, Sanchez A, Attalla K, Weng S, Voss M, Motzer RJ, Russo P, ... ... Reznik E, et al. Putative Drivers of Aggressiveness in TCEB1-mutant Renal Cell Carcinoma: An Emerging Entity with Variable Clinical Course. European Urology Focus. PMID 31813809 DOI: 10.1016/J.Euf.2019.11.013  0.342
2019 DiNatale RG, Xie W, Becerra MF, Silagy AW, Attalla K, Sanchez A, Mano R, Marcon J, Blum KA, Benfante NE, Voss MH, Motzer RJ, Coleman J, Choueiri TK, Reznik E, et al. The Association Between Small Primary Tumor Size and Prognosis in Metastatic Renal Cell Carcinoma: Insights from Two Independent Cohorts of Patients Who Underwent Cytoreductive Nephrectomy. European Urology Oncology. PMID 31735646 DOI: 10.1016/J.Euo.2019.10.002  0.317
2019 Vasan N, Razavi P, Johnson JL, Shao H, Shah H, Antoine A, Ladewig E, Gorelick A, Lin TY, Toska E, Xu G, Kazmi A, Chang MT, Taylor BS, Dickler MN, ... ... Reznik E, et al. Double mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors. Science (New York, N.Y.). 366: 714-723. PMID 31699932 DOI: 10.1126/Science.Aaw9032  0.355
2019 Granlund KL, Tee SS, Vargas HA, Lyashchenko SK, Reznik E, Fine S, Laudone V, Eastham JA, Touijer KA, Reuter VE, Gonen M, Sosa RE, Nicholson D, Guo YW, Chen AP, et al. Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1. Cell Metabolism. PMID 31564440 DOI: 10.1016/J.Cmet.2019.08.024  0.372
2019 DiNatale RG, Sanchez A, Hakimi AA, Reznik E. Metabolomics informs common patterns of molecular dysfunction across histologies of renal cell carcinoma. Urologic Oncology. PMID 31155438 DOI: 10.1016/J.Urolonc.2019.04.028  0.472
2019 Xu J, Reznik E, Lee HJ, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra JG, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka ZP, Casuscelli J, et al. Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma. Elife. 8. PMID 30924768 DOI: 10.7554/Elife.38986  0.545
2019 Xu J, Reznik E, Lee H, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra J, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka Z, Casuscelli J, et al. Author response: Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma Elife. DOI: 10.7554/Elife.38986.025  0.54
2019 Vasan N, Razavi P, Johnson J, Shao H, Shah H, Antoine A, Ladewig E, Gorelick A, Toska E, Xu G, Kazmi A, Chang MT, Taylor BS, Dickler MN, Jhaveri K, ... ... Reznik E, et al. Abstract 3917: DoublePIK3CAmutations incisenhance oncogene activation and sensitivity to PI3K alpha inhibitors in breast cancer Cancer Research. 79: 3917-3917. DOI: 10.1158/1538-7445.Am2019-3917  0.366
2019 Vasan N, Razavi P, Johnson J, Shao H, Reznik E, Smith M, Sebra R, Cantley L, Scaltriti M, Baselga J. Double PIK3CA mutations in cis enhance PI3Kα oncogene activation and sensitivity to PI3Kα inhibitors in breast cancer Annals of Oncology. 30: iii1. DOI: 10.1093/Annonc/Mdz095  0.302
2018 Harding JJ, Lowery MA, Shih AH, Schvartzman JM, Hou S, Famulare C, Patel M, Roshal M, Do RK, Zehir A, You D, Selcuklu SD, Viale A, Tallman MS, Hyman DM, ... Reznik E, et al. Isoform switching as a mechanism of acquired resistance to mutant isocitrate dehydrogenase inhibition. Cancer Discovery. PMID 30355724 DOI: 10.1158/2159-8290.Cd-18-0877  0.308
2018 Ganly I, Makarov V, Deraje S, Dong Y, Reznik E, Seshan V, Nanjangud G, Eng S, Bose P, Kuo F, Morris LGT, Landa I, Carrillo Albornoz PB, Riaz N, Nikiforov YE, et al. Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes. Cancer Cell. 34: 256-270.e5. PMID 30107176 DOI: 10.1016/J.Ccell.2018.07.002  0.377
2018 Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, et al. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports. 23: 3698. PMID 29925010 DOI: 10.1016/J.Celrep.2018.06.032  0.32
2018 Priolo C, Khabibullin D, Reznik E, Filippakis H, Ogórek B, Kavanagh TR, Nijmeh J, Herbert ZT, Asara JM, Kwiatkowski DJ, Wu CL, Henske EP. Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 29891694 DOI: 10.1073/Pnas.1710849115  0.424
2018 Turajlic S, Xu H, Litchfield K, Rowan A, Chambers T, Lopez JI, Nicol D, O'Brien T, Larkin J, Horswell S, Stares M, Au L, Jamal-Hanjani M, Challacombe B, Chandra A, ... ... Reznik E, et al. Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal. Cell. PMID 29656895 DOI: 10.1016/J.Cell.2018.03.057  0.335
2018 Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, et al. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports. 23: 313-326.e5. PMID 29617669 DOI: 10.1016/J.Celrep.2018.03.075  0.457
2018 Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, Han GC, Coleman I, Montgomery B, Pritchard C, Morrissey C, Barbieri CE, Beltran H, et al. The long tail of oncogenic drivers in prostate cancer. Nature Genetics. PMID 29610475 DOI: 10.1038/S41588-018-0078-Z  0.355
2018 Reznik E, Luna A, Aksoy BA, Liu EM, La K, Ostrovnaya I, Creighton CJ, Hakimi AA, Sander C. A Landscape of Metabolic Variation across Tumor Types. Cell Systems. PMID 29396322 DOI: 10.1016/J.Cels.2017.12.014  0.735
2018 Gorelick AN, Reznik E, Cai Y, Bielski C, Bandlamudi C, Penson A, Jonsson P, La K, Scaltriti M, Schultz N, Taylor BS. Abstract 5355: Multiple mutations to the same gene are selected for and cooperate to drive cancer Cancer Research. 78: 5355-5355. DOI: 10.1158/1538-7445.Am2018-5355  0.378
2018 Dong Y, Ganly I, Makarov V, Kuo F, Deraje S, Reznik E, Seshan V, Nanjangud G, Morris L, Riaz N, Sherman E, Ghossein R, Fagin J, Chan T. Abstract 4619: Integrated genomic analysis of Hurthle cell carcinoma reveals TMEM233/PRKAB1 fusion as a novel oncogenic driver Cancer Research. 78: 4619-4619. DOI: 10.1158/1538-7445.Am2018-4619  0.369
2018 Sanchez-Vega F, Chatila WK, Ganesh K, Penson A, Camacho N, Jonsson P, Reznik E, Gao J, Yaeger R, Berger MF, Taylor BS, Schultz N. Abstract 3024: Genomic characterization of organ-specific metastasis from prospective clinical sequencing of 20,000 cancer patients Cancer Research. 78: 3024-3024. DOI: 10.1158/1538-7445.Am2018-3024  0.373
2018 Nassau DE, Sanchez A, Dinatale R, Blum KA, Ghanaat M, Gupta S, Arcila ME, Voss MH, Motzer RJ, Russo P, Coleman J, Reznik E, Reuter V, Hakimi AA. MP28-08 CLINICOPATHOLOGIC AND GENOMIC EVALUATION OF TRANSLOCATION RENAL CELL CARCINOMA Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.908  0.319
2017 Becerra MF, Reznik E, Redzematovic A, Tennenbaum DM, Kashan M, Ghanaat M, Casuscelli J, Manley B, Jonsson P, DiNatale RG, Blum KA, Durack JC, Solomon SB, Arcila ME, Bourque C, et al. Comparative Genomic Profiling of Matched Primary and Metastatic Tumors in Renal Cell Carcinoma. European Urology Focus. PMID 29066084 DOI: 10.1016/J.Euf.2017.09.016  0.345
2017 Casuscelli J, Becerra MF, Manley BJ, Zabor EC, Reznik E, Redzematovic A, Arcila ME, Tennenbaum DM, Ghanaat M, Kashan M, Stief CG, Carlo M, Voss MH, Feldman DR, Motzer RJ, et al. Characterization and Impact of TERT Promoter Region Mutations on Clinical Outcome in Renal Cell Carcinoma. European Urology Focus. PMID 28951115 DOI: 10.1016/J.Euf.2017.09.008  0.351
2017 Reznik E, Christodoulou D, Goldford JE, Briars E, Sauer U, Segrè D, Noor E. Genome-Scale Architecture of Small Molecule Regulatory Networks and the Fundamental Trade-Off between Regulation and Enzymatic Activity. Cell Reports. 20: 2666-2677. PMID 28903046 DOI: 10.1016/J.Celrep.2017.08.066  0.735
2017 Rosenzweig B, Rubinstein ND, Reznik E, Shingarev R, Juluru K, Akin O, Hsieh JJ, Jaimes EA, Russo P, Susztak K, Coleman JA, Hakimi AA. Benign and tumor parenchyma metabolomic profiles affect compensatory renal growth in renal cell carcinoma surgical patients. Plos One. 12: e0180350. PMID 28727768 DOI: 10.1371/Journal.Pone.0180350  0.319
2017 Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, ... ... Reznik E, et al. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Reports. 19: 2878-2880. PMID 28658632 DOI: 10.1016/J.Celrep.2017.06.008  0.502
2017 Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, ... ... Reznik E, et al. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Reports. 18: 2780-2794. PMID 28297679 DOI: 10.1016/J.Celrep.2017.02.033  0.539
2017 Barenholz U, Davidi D, Reznik E, Bar-On Y, Antonovsky N, Noor E, Milo R. Design principles of autocatalytic cycles constrain enzyme kinetics and force low substrate saturation at flux branch points. Elife. 6. PMID 28169831 DOI: 10.7554/Elife.20667  0.386
2017 Reznik E, Wang Q, La K, Schultz N, Sander C. Mitochondrial respiratory gene expression is suppressed in many cancers. Elife. 6. PMID 28099114 DOI: 10.7554/Elife.21592  0.525
2017 Rosenzweig B, Rubinstein ND, Reznik E, Zareba P, Shingarev R, Juluru K, Akin O, Hsieh JJ, Jaimes E, Russo P, Susztak K, Coleman JA, Hakimi AA. MP73-17 BENIGN AND TUMOR PARENCHYMA METABOLOMIC PROFILES AFFECT COMPENSATORY RENAL GROWTH IN RENAL CELL CARCINOMA SURGICAL PATIENTS Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.3362  0.327
2017 Becerra M, Sanchez-Vega F, Reznik E, Manley B, Kashan M, Ghanaat M, Casuscelli J, Redzematovic A, Mendonca S, Arcila M, Coleman J, Russo P, Hsieh J, Hakimi AA. MP39-03 IMPACT OF SOMATIC MUTATIONS ON PATTERNS OF METASTASIS IN CLEAR CELL RENAL CELL CARCINOMA Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1177  0.334
2017 Becerra M, Reznik E, Tennenbaum D, Kashan M, Ghanaat M, Casuscelli J, Manley B, Redzematovic A, Mendonca S, Arcila M, Coleman J, Russo P, Hsieh J, Hakimi AA. MP39-02 COMPARATIVE GENOMIC PROFILING OF MATCHED PRIMARY AND METASTATIC TUMORS IN RENAL CELL CARCINOMA Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1176  0.352
2017 Manley B, Reznik E, Becerra M, Casuscelli J, Tennenbaum D, Ghanaat M, Kashan M, Redzematovic A, Sato Y, Arcila M, Voss M, Feldman D, Russo P, Coleman J, Hsieh J, et al. MP39-01 CHARACTERIZING RECURRENT AND LETHAL SMALL RENAL MASSES IN CLEAR CELL RENAL CELL CARCINOMA USING SOMATIC MUTATIONS Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1175  0.328
2016 Dong Y, Manley BJ, Becerra MF, Redzematovic A, Casuscelli J, Tennenbaum DM, Reznik E, Han S, Benfante N, Chen YB, Arcila ME, Aras O, Voss MH, Feldman DR, Motzer RJ, et al. Tumor Xenografts of Human Clear Cell Renal Cell Carcinoma But Not Corresponding Cell Lines Recapitulate Clinical Response to Sunitinib: Feasibility of Using Biopsy Samples. European Urology Focus. PMID 28753786 DOI: 10.1016/J.Euf.2016.08.005  0.309
2016 Zhao Q, Stettner AI, Reznik E, Paschalidis ICh, Segrè D. Mapping the landscape of metabolic goals of a cell. Genome Biology. 17: 109. PMID 27215445 DOI: 10.1186/S13059-016-0968-2  0.652
2016 Chen F, Zhang Y, Şenbabaoğlu Y, Ciriello G, Yang L, Reznik E, Shuch B, Micevic G, De Velasco G, Shinbrot E, Noble MS, Lu Y, Covington KR, Xi L, Drummond JA, et al. Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. Cell Reports. PMID 26947078 DOI: 10.1016/J.Celrep.2016.02.024  0.543
2016 Reznik E, Miller ML, Şenbabaoğlu Y, Riaz N, Sarungbam J, Tickoo SK, Al-Ahmadie HA, Lee W, Seshan VE, Hakimi AA, Sander C. Mitochondrial DNA copy number variation across human cancers. Elife. 5. PMID 26901439 DOI: 10.7554/Elife.10769  0.547
2016 Hakimi AA, Reznik E, Lee CH, Creighton CJ, Brannon AR, Luna A, Aksoy BA, Liu EM, Shen R, Lee W, Chen Y, Stirdivant SM, Russo P, Chen YB, Tickoo SK, et al. An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma. Cancer Cell. 29: 104-116. PMID 26766592 DOI: 10.1016/J.Ccell.2015.12.004  0.737
2016 Reznik E, Wang Q, La K, Schultz N, Sander C. Author response: Mitochondrial respiratory gene expression is suppressed in many cancers Elife. DOI: 10.7554/Elife.21592.018  0.482
2016 Rosenzweig B, Reznik E, Shingarev R, Zabor EC, Stirdivant S, Sander C, Hsieh JJ, Jaimes EA, Russo P, Hakimi AA, Coleman JA. MP85-20 METABOLOMICS AND POST-NEPHRECTOMY RENAL FUNCTION PREDICTION Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.2286  0.46
2015 Miller ML, Reznik E, Gauthier NP, Aksoy BA, Korkut A, Gao J, Ciriello G, Schultz N, Sander C. Pan-Cancer Analysis of Mutation Hotspots in Protein Domains. Cell Systems. 1: 197-209. PMID 27135912 DOI: 10.1016/J.Cels.2015.08.014  0.735
2015 Gauthier NP, Reznik E, Gao J, Sumer SO, Schultz N, Sander C, Miller ML. MutationAligner: a resource of recurrent mutation hotspots in protein domains in cancer. Nucleic Acids Research. PMID 26590264 DOI: 10.1093/Nar/Gkv1132  0.544
2015 Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, ... ... Reznik E, et al. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. The New England Journal of Medicine. PMID 26536169 DOI: 10.1056/Nejmoa1505917  0.338
2015 Sandhu R, Georgiou T, Reznik E, Zhu L, Kolesov I, Senbabaoglu Y, Tannenbaum A. Graph Curvature for Differentiating Cancer Networks. Scientific Reports. 5: 12323. PMID 26169480 DOI: 10.1038/Srep12323  0.307
2015 Reznik E, Sander C. Extensive decoupling of metabolic genes in cancer. Plos Computational Biology. 11: e1004176. PMID 25961905 DOI: 10.1371/Journal.Pcbi.1004176  0.59
2015 Reznik E, Miller ML, Şenbabaoğlu Y, Riaz N, Sarungbam J, Tickoo SK, Al-Ahmadie HA, Lee W, Seshan VE, Hakimi AA, Sander C. Author response: Mitochondrial DNA copy number variation across human cancers Elife. DOI: 10.7554/Elife.10769.028  0.466
2015 Miller ML, Reznik E, Gauthier NP, Aksoy BA, Korkut A, Gao J, Ciriello G, Schultz N, Sander C. Pan-Cancer Analysis of Mutation Hotspots in Protein Domains Cell Systems. 1: 197-209. DOI: 10.1016/S0959-8049(16)61060-2  0.657
2014 Noor E, Bar-Even A, Flamholz A, Reznik E, Liebermeister W, Milo R. Pathway thermodynamics highlights kinetic obstacles in central metabolism. Plos Computational Biology. 10: e1003483. PMID 24586134 DOI: 10.1371/Journal.Pcbi.1003483  0.372
2013 Reznik E, Mehta P, Segrè D. Flux imbalance analysis and the sensitivity of cellular growth to changes in metabolite pools. Plos Computational Biology. 9: e1003195. PMID 24009492 DOI: 10.1371/Journal.Pcbi.1003195  0.403
2013 Reznik E, Chaudhary O, Segrè D. The average enzyme principle. Febs Letters. 587: 2891-4. PMID 23892076 DOI: 10.1016/J.Febslet.2013.07.032  0.598
2013 Reznik E, Kaper TJ, Segrè D. The dynamics of hybrid metabolic-genetic oscillators. Chaos (Woodbury, N.Y.). 23: 013132. PMID 23556969 DOI: 10.1063/1.4793573  0.641
2013 Reznik E, Watson A, Chaudhary O. The stubborn roots of metabolic cycles. Journal of the Royal Society, Interface / the Royal Society. 10: 20130087. PMID 23554346 DOI: 10.1098/Rsif.2013.0087  0.382
2013 Reznik E, Yohe S, Segrè D. Invariance and optimality in the regulation of an enzyme. Biology Direct. 8: 7. PMID 23522082 DOI: 10.1186/1745-6150-8-7  0.617
2012 Collins SB, Reznik E, Segrè D. Temporal expression-based analysis of metabolism. Plos Computational Biology. 8: e1002781. PMID 23209390 DOI: 10.1371/Journal.Pcbi.1002781  0.751
2010 Reznik E, Segrè D. On the stability of metabolic cycles. Journal of Theoretical Biology. 266: 536-49. PMID 20673772 DOI: 10.1016/J.Jtbi.2010.07.023  0.639
Low-probability matches (unlikely to be authored by this person)
2018 Wang Q, Armenia J, Zhang C, Penson AV, Reznik E, Zhang L, Minet T, Ochoa A, Gross BE, Iacobuzio-Donahue CA, Betel D, Taylor BS, Gao J, Schultz N. Unifying cancer and normal RNA sequencing data from different sources. Scientific Data. 5: 180061. PMID 29664468 DOI: 10.1038/Sdata.2018.61  0.293
2022 Yoo A, Tang C, Zucker M, Fitzgerald K, DiNatale RG, Rappold PM, Weiss K, Freeman B, Lee CH, Schultz N, Motzer R, Russo P, Coleman J, Reuter VE, Chen YB, ... ... Reznik E, et al. Genomic and Metabolic Hallmarks of SDH- and FH-deficient Renal Cell Carcinomas. European Urology Focus. PMID 35288096 DOI: 10.1016/j.euf.2021.12.002  0.292
2019 Mano* R, Di Natale R, Drill E, Sankin A, Winer A, Silagy A, Marcon J, Blum K, Reznik E, Coleman J, Ostrovnaya I, Russo P, Hakimi AA. MP16-16 IDENTIFYING CLEAR CELL RCC CLONALITY THROUGH ULTRA-DEEP SEQUENCING OF POOLED REGIONAL TUMOR DNA Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555352.51923.C5  0.287
2022 Ganly I, Liu EM, Kuo F, Makarov V, Dong Y, Park J, Gong Y, Gorelick AN, Knauf JA, Benedetti E, Tait-Mulder J, Morris LGT, Fagin JA, Intlekofer AM, Krumsiek J, ... ... Reznik E, et al. Mitonuclear genotype remodels the metabolic and microenvironmental landscape of Hürthle cell carcinoma. Science Advances. 8: eabn9699. PMID 35731870 DOI: 10.1126/sciadv.abn9699  0.281
2020 Marcon J, Kuo F, Weiss* K, DiNatale RG, Weng S, Silagy AW, Attalla K, Coleman JA, Russo P, Reznik E, Chan TA, Akin O, Hakimi AA. MP08-12 TRANSCRIPTIONAL PROGRAMS IN CLEAR CELL RENAL CELL CARCINOMAS WITH NECROSIS ON IMAGING The Journal of Urology. 203: e110. DOI: 10.1097/Ju.0000000000000828.012  0.276
2019 Sanchez-Vega F, Fong C, Chatila W, Jonsson P, Penson AV, DiNatale RG, Berger MF, Zehir A, Reznik E, Gao J, Ganesh K, Taylor BS, Schultz N. Abstract 2736: A molecular and histopathologic map of cancer metastasis Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2736  0.275
2022 Tourigny DS, Zucker M, Kim M, Russo P, Coleman J, Lee CH, Carlo MI, Chen YB, Hakimi AA, Kotecha RR, Reznik E. Molecular Characterization of the Tumor Microenvironment in Renal Medullary Carcinoma. Frontiers in Oncology. 12: 910147. PMID 35837094 DOI: 10.3389/fonc.2022.910147  0.272
2017 Barenholz U, Davidi D, Reznik E, Bar-On Y, Antonovsky N, Noor E, Milo R. Author response: Design principles of autocatalytic cycles constrain enzyme kinetics and force low substrate saturation at flux branch points Elife. DOI: 10.7554/Elife.20667.013  0.272
2020 Parsa S, Ortega-Molina A, Ying HY, Jiang M, Teater M, Wang J, Zhao C, Reznik E, Pasion JP, Kuo D, Mohan P, Wang S, Camarillo JM, Thomas PM, Jain N, et al. The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. Nature Cancer. 1: 653-664. PMID 33569544 DOI: 10.1038/s43018-020-0080-0  0.268
2019 Xu B, Reznik E, Tuttle RM, Knauf J, Fagin JA, Katabi N, Dogan S, Aleynick N, Seshan V, Middha S, Enepekides D, Casadei GP, Solaroli E, Tallini G, Ghossein R, et al. Outcome and molecular characteristics of non-invasive encapsulated follicular variant of papillary thyroid carcinoma with oncocytic features. Endocrine. PMID 30689169 DOI: 10.1007/S12020-019-01848-6  0.263
2024 Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, et al. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports. 43: 113063. PMID 38578829 DOI: 10.1016/j.celrep.2023.113063  0.258
2018 Dubard Gault M, Mandelker D, DeLair D, Stewart CR, Kemel Y, Sheehan MR, Siegel B, Kennedy J, Marcell V, Arnold A, Al-Ahmadie H, Modak S, Robson M, Shukla N, Roberts S, ... ... Reznik E, et al. Germline mutations in children and adults with cancer. Cold Spring Harbor Molecular Case Studies. 4. PMID 30068732 DOI: 10.1101/mcs.a002584  0.257
2019 Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, Han GC, Coleman I, Montgomery B, Pritchard C, Morrissey C, Barbieri CE, Beltran H, et al. Publisher Correction: The long tail of oncogenic drivers in prostate cancer. Nature Genetics. PMID 31152158 DOI: 10.1038/S41588-019-0451-6  0.253
2023 Kotecha RR, Doshi SD, Knezevic A, Chaim J, Chen Y, Jacobi R, Zucker M, Reznik E, McHugh D, Shah NJ, Feld E, Aggen DH, Rafelson W, Xiao H, Carlo MI, et al. A Phase 2 Trial of Talazoparib and Avelumab in Genomically Defined Metastatic Kidney Cancer. European Urology Oncology. PMID 37945488 DOI: 10.1016/j.euo.2023.10.017  0.251
2022 Nguyen B, Fong C, Luthra A, Smith SA, DiNatale RG, Nandakumar S, Walch H, Chatila WK, Madupuri R, Kundra R, Bielski CM, Mastrogiacomo B, Donoghue MTA, Boire A, Chandarlapaty S, ... ... Reznik E, et al. Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients. Cell. 185: 563-575.e11. PMID 35120664 DOI: 10.1016/j.cell.2022.01.003  0.25
2023 Tang C, Xie AX, Liu EM, Kuo F, Kim M, DiNatale RG, Golkaram M, Chen YB, Gupta S, Motzer RJ, Russo P, Coleman J, Carlo MI, Voss MH, Kotecha RR, ... ... Reznik E, et al. Immunometabolic coevolution defines unique microenvironmental niches in ccRCC. Cell Metabolism. PMID 37413991 DOI: 10.1016/j.cmet.2023.06.005  0.249
2021 Gorelick AN, Kim M, Chatila WK, La K, Hakimi AA, Berger MF, Taylor BS, Gammage PA, Reznik E. Respiratory complex and tissue lineage drive recurrent mutations in tumour mtDNA. Nature Metabolism. PMID 33833465 DOI: 10.1038/s42255-021-00378-8  0.243
2016 Zhao Q, Stettner A, Reznik E, Segre D, Paschalidis IC. Learning cellular objectives from fluxes by inverse optimization Proceedings of the Ieee Conference On Decision and Control. 2016: 1271-1276. DOI: 10.1109/CDC.2015.7402386  0.232
2022 Freeman BA, Jaro S, Park T, Keene S, Tansey W, Reznik E. MIRTH: Metabolite Imputation via Rank-Transformation and Harmonization. Genome Biology. 23: 184. PMID 36050754 DOI: 10.1186/s13059-022-02738-3  0.223
2021 Reznik E, Jiang H, Hakimi AA. Chemerin Tips the Scales in ccRCC to Evade Ferroptosis. Cancer Discovery. 11: 1879-1880. PMID 34344758 DOI: 10.1158/2159-8290.CD-21-0610  0.217
2020 Hadi K, Yao X, Behr JM, Deshpande A, Xanthopoulakis C, Tian H, Kudman S, Rosiene J, Darmofal M, DeRose J, Mortensen R, Adney EM, Shaiber A, Gajic Z, Sigouros M, ... ... Reznik E, et al. Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs. Cell. 183: 197-210.e32. PMID 33007263 DOI: 10.1016/j.cell.2020.08.006  0.216
2021 DiNatale RG, Mano R, Makarov V, Rusk N, Drill E, Winer A, Sankin A, Yoo A, Freeman BA, Hsieh JJ, Chen YB, Coleman JA, Berger M, Ostrovnaya I, Chan TA, ... ... Reznik E, et al. Resource-efficient pooled sequencing expands translational impact in solid tumors. Kidney Cancer Journal : Official Journal of the Kidney Cancer Association. 19: 18-23. PMID 34316321 DOI: 10.52733/KCJ18n2.a1  0.212
2021 Dong Y, Gong Y, Kuo F, Makarov V, Reznik E, Nanjangud GJ, Aras O, Zhao H, Qu R, Fagin JA, Sherman EJ, Xu B, Ghossein R, Chan TA, Ganly I. Targeting the mTOR Pathway in Hurthle Cell Carcinoma Results in Potent Anti-Tumor Activity. Molecular Cancer Therapeutics. PMID 34789562 DOI: 10.1158/1535-7163.MCT-21-0224  0.203
2017 Manley BJ, Reznik E, Ghanaat M, Kashan M, Becerra MF, Casuscelli J, Tennenbaum D, Redzematovic A, Carlo MI, Sato Y, Arcila M, Voss MH, Feldman DR, Motzer RJ, Russo P, et al. Characterizing recurrent and lethal small renal masses in clear cell renal cell carcinoma using recurrent somatic mutations. Urologic Oncology. PMID 29132830 DOI: 10.1016/J.Urolonc.2017.10.012  0.199
2021 Attalla K, DiNatale RG, Rappold PM, Fong CJ, Sanchez-Vega F, Silagy AW, Weng S, Coleman J, Lee CH, Carlo MI, Durack JC, Solomon SB, Reuter V, Russo P, Chan TA, ... ... Reznik E, et al. Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34261695 DOI: 10.1158/1078-0432.CCR-20-4058  0.198
2022 Golkaram M, Kuo F, Gupta S, Carlo MI, Salmans ML, Vijayaraghavan R, Tang C, Makarov V, Rappold P, Blum KA, Zhao C, Mehio R, Zhang S, Godsey J, Pawlowski T, ... ... Reznik E, et al. Spatiotemporal evolution of the clear cell renal cell carcinoma microenvironment links intra-tumoral heterogeneity to immune escape. Genome Medicine. 14: 143. PMID 36536472 DOI: 10.1186/s13073-022-01146-3  0.196
2022 Rappold PM, Vuong L, Leibold J, Chakiryan NH, Curry M, Kuo F, Sabio E, Jiang H, Nixon BG, Liu M, Berglund AE, Silagy AW, Mascareno A, Golkaram M, Marker M, ... ... Reznik E, et al. A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear Cell Renal Cell Carcinoma. Cancer Discovery. PMID 35758895 DOI: 10.1158/2159-8290.CD-21-0925  0.19
2020 Weng S, DiNatale RG, Silagy A, Mano R, Attalla K, Kashani M, Weiss K, Benfante NE, Winer AG, Coleman JA, Reuter VE, Russo P, Reznik E, Tickoo SK, Hakimi AA. The Clinicopathologic and Molecular Landscape of Clear Cell Papillary Renal Cell Carcinoma: Implications in Diagnosis and Management. European Urology. PMID 33046271 DOI: 10.1016/j.eururo.2020.09.027  0.187
2021 Lee CH, DiNatale RG, Chowell D, Krishna C, Makarov V, Valero C, Vuong L, Lee M, Weiss K, Hoen D, Morris L, Reznik E, Murray S, Kotecha R, Voss MH, et al. High response rate and durability driven by HLA genetic diversity in kidney cancer patients treated with the immunotherapy combination lenvatinib and pembrolizumab. Molecular Cancer Research : McR. PMID 34039647 DOI: 10.1158/1541-7786.MCR-21-0053  0.178
2021 Silagy AW, Attalla K, Dinatale RG, Weiss KL, Weng S, Mano R, Iosepovici S, Marcon J, Reznik E, Kotecha RR, Motzer RJ, Voss MH, Coleman JA, Hakimi AA, Russo P. A qualitative framework of non-selection factors for cytoreductive nephrectomy. World Journal of Urology. PMID 33779820 DOI: 10.1007/s00345-021-03650-4  0.174
2021 Gleeson JP, Nikolovski I, DiNatale RG, Zucker M, Knezevic A, Patil S, Ged Y, Kotecha RR, Shapnik N, Murray S, Russo P, Coleman J, Lee CH, Stadler ZK, Hakimi AA, ... ... Reznik E, et al. Comprehensive Molecular Characterization and Response to Therapy in FH-Deficient Renal Cell Carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33658299 DOI: 10.1158/1078-0432.CCR-20-4367  0.172
2024 Tang C, Castillon VJ, Waters M, Fong C, Park T, Boscenco S, Kim S, Schultz N, Ostrovnaya I, Gusev A, Jee J, Reznik E. Obesity shapes selection for driver mutations in cancer. Medrxiv : the Preprint Server For Health Sciences. PMID 38260500 DOI: 10.1101/2024.01.10.24301114  0.161
2023 Posada Calderon L, Eismann L, Reese SW, Reznik E, Hakimi AA. Advances in Imaging-Based Biomarkers in Renal Cell Carcinoma: A Critical Analysis of the Current Literature. Cancers. 15. PMID 36672304 DOI: 10.3390/cancers15020354  0.155
2022 Lee CH, Voss MH, Carlo MI, Chen YB, Zucker M, Knezevic A, Lefkowitz RA, Shapnik N, Dadoun C, Reznik E, Shah NJ, Owens CN, McHugh DJ, Aggen DH, Laccetti AL, et al. Phase II Trial of Cabozantinib Plus Nivolumab in Patients With Non-Clear-Cell Renal Cell Carcinoma and Genomic Correlates. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2101944. PMID 35298296 DOI: 10.1200/JCO.21.01944  0.142
2023 Kotecha RR, Knezevic A, Arora K, Bandlamudi C, Kuo F, Carlo MI, Fitzgerald KN, Feldman DR, Shah NJ, Reznik E, Hakimi AA, Carrot-Zhang J, Mandelker D, Berger M, Lee CH, et al. Genomic ancestry in kidney cancer: Correlations with clinical and molecular features. Cancer. PMID 37864521 DOI: 10.1002/cncr.35074  0.136
2023 Hoxhaj G, Reznik E. Career pathways, part 11. Nature Metabolism. 5: 716-719. PMID 37142788 DOI: 10.1038/s42255-023-00788-w  0.12
2010 Reznik E, Gendlin G, Storojhakov G, Guschina V, Volinkina V, Baranich I, Tursheva M. VITAMIN D, PARATHYROID HORMONE, CALCITONIN AND DISTURBANCES OF CALCIUM AND PHOSPHORUS METABOLISM IN ARTERIAL HYPERTENSION PATIENTS: PP.30.186 Journal of Hypertension. 28: e505. DOI: 10.1097/01.hjh.0000379724.38534.c8  0.114
2022 Mano R, Hoeh B, DiNatale RG, Sanchez A, Benfante NE, Reznik E, Leitao MM, Shoushtari AN, Goh A, Donat SM, Herr HW, Bochner BH, Dalbagni G, Donahue TF. Urethral Melanoma - Clinical, Pathological and Molecular Characteristics. Bladder Cancer (Amsterdam, Netherlands). 8: 291-301. PMID 36277327 DOI: 10.3233/BLC-211633  0.079
2023 Boscenco S, Reznik E. Mitochondrial DNA comes with nuclear strings attached. Nature. 620: 732-734. PMID 37587274 DOI: 10.1038/d41586-023-01783-7  0.077
2010 Kharchenko UV, Beleneva IA, Karpov VA, Reznik EP. Microbiological activity of fouling communities as indicator of biocorrosion aggressiveness of sea water Protection of Metals and Physical Chemistry of Surfaces. 46: 842-845. DOI: 10.1134/S2070205110070191  0.076
1996 Pankratova EM, Domracheva LI, Reznik EN. Changes in the parameters of algal-Cyanobacterial soil communities under the impact of fertilizers Eurasian Soil Science. 29: 1035-1040.  0.07
1994 McDaniel FD, Anthony JM, Kirchhoff JF, Marble DK, Kim YD, Renfrow SN, Grannan BC, Reznik ER, Vizkelethy G, Matteson S. Impurity determination in electronic materials by accelerator mass spectrometry Nuclear Inst. and Methods in Physics Research, B. 89: 242-249. DOI: 10.1016/0168-583X(94)95181-0  0.044
2015 Quartararo CE, Reznik E, DeCarvalho AC, Mikkelsen T, Stockwell BR. High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma Acs Medicinal Chemistry Letters. 6: 948-952. DOI: 10.1021/acsmedchemlett.5b00128  0.042
2015 Guarrera JV, Henry SD, Samstein B, Reznik E, Musat C, Lukose TI, Ratner LE, Brown RS, Kato T, Emond JC. Hypothermic machine preservation facilitates successful transplantation of "orphan" extended criteria donor livers. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15: 161-9. PMID 25521639 DOI: 10.1111/Ajt.12958  0.035
2003 Reznik EL, Shtejntsajg RM. Improvement in efficiency and application of geotechnologies Tyazheloe Mashinostroenie. 9-13.  0.028
1986 Reznik EP, Kuznetsova LA. Emergence of Thamugadia ivaschkini microfilaria from the stomach into the hemocoel of Sergentomyia arpaklensis sandflies Parazitologiia. 20: 300-306. PMID 3748606  0.027
1998 Pankratova EM, Borodina NV, Reznik EN. Nitrogen fixation by the nonheterocystous cyanobacterium phormidium inundatum Mikrobiologiya. 67: 754-761.  0.027
1985 Reznik EP, Korenberg EI, Murtazaev DM, Amridinov KN. Approaches to the standardization of farms infested with Ornithodoros ticks Meditsinskaya Parazitologiya I Parazitarnye Bolezni. 77-83. PMID 3159960  0.026
1978 Aleksandrova KV, Tamarina NA, Reznik EP. Experience with the laboratory cultivation of the mosquito, Aedes togoi (Culicidae) Parazitologiia. 12: 167-169. PMID 643313  0.025
1975 Fedder ML, Reznik EP. Materials for determination of physiological age and gonotrophic cycle duration in mosquito Anopheles hyrcanus in the south of the Azerbajan SSR (Russian) Meditsinskaya Parazitologiya I Parazitarnye Bolezni. 44: 725-728. PMID 129669  0.022
1983 Reznik EP, Korenberg EI, Kriuchechnikov VN. Current status of foci of tick-borne borreliosis in the southern Turkmen SSR Meditsinskaya Parazitologiya I Parazitarnye Bolezni. 52: 28-30. PMID 6225007  0.02
1971 Fedder ML, Reznik EP, Danilevskiǐ ML, Mantukhov AG, Trotskaia DF. Epidemiologic evaluation of natural populations of Aëdes togoi Theobald in Soviet Primor'e Meditsinskaya Parazitologiya I Parazitarnye Bolezni. 40: 301-307. PMID 4329114  0.02
1983 Reznik EP, Kuznetsova LA. Passage of the microfilaria, Thamugadia ivaschkini, from the intestine into the hemocele of the sand flies of the genus Phlebotomus Parazitologiia. 17: 36-41. PMID 6844031  0.017
1990 Reznik EP. Quantitative experimental assessment of the efficacy of Borrelia persica transmission by Ornithodoros papillipes. I. Forms of borreliemia in guinea pigs Meditsinskaya Parazitologiya I Parazitarnye Bolezni. 17-21. PMID 2215365  0.013
1980 Dzhurinskii BF, Zorina LN, Lysanova GV, Komova MG, Soshchin NP, Tananaev IV, Reznik EM. Luminescence Properties of Double Molybdates and Tungstates of Rare Earth and Alkali Metals Neorganiceskie Materialy. 16: 110-113.  0.012
1982 Reznik EP. Vectors of the filaria Thamugadia ivaschkini (Splendidofilariidae) in the southern Turkmen SSR Parazitologiia. 16: 390-394. PMID 6216450  0.01
1971 Fedder ML, Danilevskiǐ ML, Reznik EP. Discovery of a parasitic fungus of the genus coelomomyces (Phycomycetes, Blastocladiales) in Aedes togoi, Theobald mosquitoes in the Primorsk region Meditsinskaya Parazitologiya I Parazitarnye Bolezni. 40: 201-204. PMID 4254959  0.01
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