Year |
Citation |
Score |
2018 |
Deck LM, Hunsaker LA, Vander Jagt TA, Whalen LJ, Royer RE, Vander Jagt DL. Activation of anti-oxidant Nrf2 signaling by enone analogues of curcumin. European Journal of Medicinal Chemistry. 143: 854-865. PMID 29223100 DOI: 10.1016/J.Ejmech.2017.11.048 |
0.447 |
|
2018 |
Deck L, Greenberg J, Whalen L, Vander Jagt D, Royer R. Synthesis of Naphthoic Acids as Potential Anticancer Agents Synlett. 30: 104-108. DOI: 10.1055/S-0037-1611342 |
0.423 |
|
2017 |
Deck LM, Whalen LJ, Hunsaker LA, Royer RE, Vander Jagt DL. Activation of anti-oxidant Nrf2 signaling by substituted trans stilbenes. Bioorganic & Medicinal Chemistry. PMID 28126440 DOI: 10.1016/J.Bmc.2017.01.005 |
0.457 |
|
2014 |
Solberg NO, Chamberlin R, Vigil JR, Deck LM, Heidrich JE, Brown DC, Brady CI, Vander Jagt TA, Garwood M, Bisoffi M, Severns V, Vander Jagt DL, Sillerud LO. Optical and SPION-enhanced MR imaging shows that trans-stilbene inhibitors of NF-κB concomitantly lower Alzheimer's disease plaque formation and microglial activation in AβPP/PS-1 transgenic mouse brain. Journal of Alzheimer's Disease : Jad. 40: 191-212. PMID 24413613 DOI: 10.3233/Jad-131031 |
0.318 |
|
2014 |
Deck LM, Paine RT, Bright ER, Ouizem S, Dickie DA. Syntheses of methylpyridine and methylpyridine N-oxide decorated benzoxazine and naphthoxazine platforms Tetrahedron Letters. 55: 2434-2437. DOI: 10.1016/J.Tetlet.2014.02.129 |
0.3 |
|
2013 |
Deck LM, Greenberg JA, Busby TS, Bright ER, Whalen LJ, Vander Jagt DL, Royer RE. Synthesis of naphthalene and indene precursors to naphthoic and indenoic acids Tetrahedron Letters. 54: 6015-6018. DOI: 10.1016/J.Tetlet.2013.08.067 |
0.402 |
|
2012 |
Deck LM, Mgani Q, Martinez A, Martinic A, Whalen LJ, Vander Jagt DL, Royer RE. Synthesis of benzyl substituted naphthalenes from benzylidene tetralones. Tetrahedron Letters. 53: 373-376. PMID 23794758 DOI: 10.1016/J.Tetlet.2011.11.065 |
0.723 |
|
2012 |
Orlando RA, Gonzales AM, Royer RE, Deck LM, Vander Jagt DL. A chemical analog of curcumin as an improved inhibitor of amyloid Abeta oligomerization. Plos One. 7: e31869. PMID 22442659 DOI: 10.1371/Journal.Pone.0031869 |
0.39 |
|
2010 |
Wei J, Vander Jagt DL, Royer RE, Deck LM. Synthesis of Hemigossypol and its Derivatives. Tetrahedron Letters. 51: 5757-5760. PMID 22837586 DOI: 10.1016/J.Tetlet.2010.08.089 |
0.402 |
|
2010 |
Shah VO, Ferguson JE, Hunsaker LA, Deck LM, Vander Jagt DL. Natural products inhibit LPS-induced activation of pro-inflammatory cytokines in peripheral blood mononuclear cells. Natural Product Research. 24: 1177-88. PMID 20582811 DOI: 10.1080/14786410903112680 |
0.374 |
|
2010 |
Le A, Cooper CR, Gouw AM, Dinavahi R, Maitra A, Deck LM, Royer RE, Vander Jagt DL, Semenza GL, Dang CV. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 2037-42. PMID 20133848 DOI: 10.1073/Pnas.0914433107 |
0.402 |
|
2010 |
Le A, Cooper CR, Gouw A, Maitra A, Dinavahi R, Deck L, Royer R, Jagt DV, Semenza G, Dang CV. Abstract 5453: Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression Cancer Research. 70: 5453-5453. DOI: 10.1158/1538-7445.Am10-5453 |
0.389 |
|
2008 |
Deck LM, Hunsaker LA, Gonzales AM, Orlando RA, Vander Jagt DL. Substituted trans-stilbenes can inhibit or enhance the TPA-induced up-regulation of activator protein-1. Bmc Pharmacology. 8: 19. PMID 19000313 DOI: 10.1186/1471-2210-8-19 |
0.459 |
|
2008 |
Heynekamp JJ, Hunsaker LA, Vander Jagt TA, Royer RE, Deck LM, Vander Jagt DL. Isocoumarin-based inhibitors of pancreatic cholesterol esterase. Bioorganic & Medicinal Chemistry. 16: 5285-94. PMID 18353652 DOI: 10.1016/J.Bmc.2008.03.016 |
0.712 |
|
2007 |
Pailloux S, Binyamin I, Deck LM, Rapko BM, Hay BP, Duesler EN, Paine RT. Oxidation reactivity channels for 2-(pyridin-2-yl)-N,N-diphenylacetamides. The Journal of Organic Chemistry. 72: 9195-202. PMID 17973526 DOI: 10.1021/Jo701408Y |
0.308 |
|
2006 |
Heynekamp JJ, Weber WM, Hunsaker LA, Gonzales AM, Orlando RA, Deck LM, Jagt DL. Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor alpha-induced activation of transcription factor nuclear factor kappaB. Journal of Medicinal Chemistry. 49: 7182-9. PMID 17125270 DOI: 10.1021/Jm060630X |
0.711 |
|
2006 |
Weber WM, Hunsaker LA, Gonzales AM, Heynekamp JJ, Orlando RA, Deck LM, Vander Jagt DL. TPA-induced up-regulation of activator protein-1 can be inhibited or enhanced by analogs of the natural product curcumin. Biochemical Pharmacology. 72: 928-40. PMID 16934760 DOI: 10.1016/J.Bcp.2006.07.007 |
0.713 |
|
2006 |
Heynekamp JJ, Hunsaker LA, Vander Jagt TA, Deck LM, Vander Jagt DL. Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator. Bmc Chemical Biology. 6: 1. PMID 16466576 DOI: 10.1186/1472-6769-6-1 |
0.72 |
|
2006 |
Weber WM, Hunsaker LA, Roybal CN, Bobrovnikova-Marjon EV, Abcouwer SF, Royer RE, Deck LM, Vander Jagt DL. Activation of NFkappaB is inhibited by curcumin and related enones. Bioorganic & Medicinal Chemistry. 14: 2450-61. PMID 16338138 DOI: 10.1016/J.Bmc.2005.11.035 |
0.688 |
|
2005 |
Weber WM, Hunsaker LA, Abcouwer SF, Deck LM, Vander Jagt DL. Anti-oxidant activities of curcumin and related enones. Bioorganic & Medicinal Chemistry. 13: 3811-20. PMID 15863007 DOI: 10.1016/J.Bmc.2005.03.035 |
0.639 |
|
2004 |
Brown WM, Yowell CA, Hoard A, Vander Jagt TA, Hunsaker LA, Deck LM, Royer RE, Piper RC, Dame JB, Makler MT, Vander Jagt DL. Comparative structural analysis and kinetic properties of lactate dehydrogenases from the four species of human malarial parasites. Biochemistry. 43: 6219-29. PMID 15147206 DOI: 10.1021/Bi049892W |
0.325 |
|
2003 |
Brown WM, Metzger LE, Barlow JP, Hunsaker LA, Deck LM, Royer RE, Vander Jagt DL. 17-beta-Hydroxysteroid dehydrogenase type 1: computational design of active site inhibitors targeted to the Rossmann fold. Chemico-Biological Interactions. 143: 481-91. PMID 12604234 DOI: 10.1016/S0009-2797(02)00184-9 |
0.448 |
|
2002 |
Stoddard Hatch M, Brown WM, Deck JA, Hunsaker LA, Deck LM, Vander Jagt DL. Inhibition of yeast lipase (CRL1) and cholesterol esterase (CRL3) by 6-chloro-2-pyrones: comparison with porcine cholesterol esterase. Biochimica Et Biophysica Acta. 1596: 381-91. PMID 12007617 DOI: 10.1016/S0167-4838(01)00304-1 |
0.434 |
|
2001 |
Dando C, Schroeder ER, Hunsaker LA, Deck LM, Royer RE, Zhou X, Parmley SF, Vander Jagt DL. The kinetic properties and sensitivities to inhibitors of lactate dehydrogenases (LDH1 and LDH2) from Toxoplasma gondii: comparisons with pLDH from Plasmodium falciparum. Molecular and Biochemical Parasitology. 118: 23-32. PMID 11704270 DOI: 10.1016/S0166-6851(01)00360-7 |
0.416 |
|
2001 |
Yu Y, Deck JA, Hunsaker LA, Deck LM, Royer RE, Goldberg E, Vander Jagt DL. Selective active site inhibitors of human lactate dehydrogenases A4, B4, and C4. Biochemical Pharmacology. 62: 81-9. PMID 11377399 DOI: 10.1016/S0006-2952(01)00636-0 |
0.408 |
|
2000 |
Vander Jagt DL, Deck LM, Royer RE. Gossypol: prototype of inhibitors targeted to dinucleotide folds. Current Medicinal Chemistry. 7: 479-98. PMID 10702620 DOI: 10.2174/0929867003375119 |
0.498 |
|
1999 |
Deck LM, Baca ML, Salas SL, Hunsaker LA, Vander Jagt DL. 3-Alkyl-6-chloro-2-pyrones: selective inhibitors of pancreatic cholesterol esterase. Journal of Medicinal Chemistry. 42: 4250-6. PMID 10514295 DOI: 10.1021/Jm990309X |
0.434 |
|
1999 |
Deck LM, Chamblee BB, Royer RE, Hunsaker LA, Jagt DLVd. Inhibition of aldose reductase by gossypol and gossypol-related compounds. Advances in Experimental Medicine and Biology. 463: 487-492. PMID 10352723 DOI: 10.1007/978-1-4615-4735-8_61 |
0.308 |
|
1998 |
Deck LM, Royer RE, Chamblee BB, Hernandez VM, Malone RR, Torres JE, Hunsaker LA, Piper RC, Makler MT, Vander Jagt DL. Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum. Journal of Medicinal Chemistry. 41: 3879-87. PMID 9748363 DOI: 10.1021/Jm980334N |
0.352 |
|
1997 |
Gomez MS, Piper RC, Hunsaker LA, Royer RE, Deck LM, Makler MT, Vander Jagt DL. Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum. Molecular and Biochemical Parasitology. 90: 235-46. PMID 9497046 DOI: 10.1016/S0166-6851(97)00140-0 |
0.343 |
|
1997 |
Vander Jagt DL, Hunsaker LA, Vander Jagt TJ, Gomez MS, Gonzales DM, Deck LM, Royer RE. Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes. Biochemical Pharmacology. 53: 1133-40. PMID 9175718 DOI: 10.1016/S0006-2952(97)00090-7 |
0.321 |
|
1995 |
Royer RE, Deck LM, Vander Jagt TJ, Martinez FJ, Mills RG, Young SA, Vander Jagt DL. Synthesis and anti-HIV activity of 1,1'-dideoxygossypol and related compounds. Journal of Medicinal Chemistry. 38: 2427-32. PMID 7608907 DOI: 10.1021/Jm00013A018 |
0.33 |
|
1992 |
Royer RE, Mills RG, Deck LM, Mertz GJ, Vander Jagt DL. Inhibition of human immunodeficiency virus type I replication by derivatives of gossypol. Pharmacological Research. 24: 407-12. PMID 1805194 DOI: 10.1016/1043-6618(91)90045-Y |
0.304 |
|
1991 |
Deck LM, Vander Jagt DL, Royer RE. Gossypol and derivatives: a new class of aldose reductase inhibitors. Journal of Medicinal Chemistry. 34: 3301-5. PMID 1956050 DOI: 10.1021/Jm00115A021 |
0.458 |
|
1990 |
Deck LM, Brazwell EM, Vander Jagt DL, Royer RE. IMPROVED SYNTHESIS OF 1,2-DIMETHOXY-3-ISOPROPYLBENZENE AND GENERAL SYNTHESIS OF 3-SUBSTITUTED-1,2-DIMETHOXYBENZENES Organic Preparations and Procedures International. 22: 495-500. DOI: 10.1080/00304949009356311 |
0.335 |
|
1987 |
Daub GH, Deck LM, Leon AA. SYNTHESIS OF 6,7,12-TRIMETHYLBENZ[a]ANTHRACENE 6,7-, AND 6,12-DIHETHYLBENZ[a]ANTHRACENE Organic Preparations and Procedures International. 19: 269-276. DOI: 10.1080/00304948709356198 |
0.321 |
|
1987 |
ROYER RE, DECK LM, CAMPOS NM, HUNSAKER LA, VANDER JAGT DL. ChemInform Abstract: Biologically Active Derivatives of Gossypol (I): Synthesis and Antimalarial Activities of Peri-Acylated Gossylic Nitriles. Cheminform. 18. DOI: 10.1002/chin.198706329 |
0.349 |
|
1986 |
Royer RE, Deck LM, Campos NM, Hunsaker LA, Vander Jagt DL. Biologically active derivatives of gossypol: synthesis and antimalarial activities of peri-acylated gossylic nitriles. Journal of Medicinal Chemistry. 29: 1799-801. PMID 3528492 DOI: 10.1021/Jm00159A043 |
0.459 |
|
1986 |
Radloff RJ, Deck LM, Royer RE, Vander Jagt DL. Antiviral activities of gossypol and its derivatives against herpes simplex virus type II. Pharmacological Research Communications. 18: 1063-73. PMID 3025895 DOI: 10.1016/0031-6989(86)90023-8 |
0.351 |
|
1984 |
DECK LM, DAUB GH. ChemInform Abstract: SYNTHESIS OF 10-(CHLOROMETHYL)BENZO(A)PYRENE Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198412181 |
0.314 |
|
1983 |
Deck LM, Daub GH. Synthesis of 10-(chloromethyl)benzo[a]pyrene The Journal of Organic Chemistry. 48: 3577-3580. DOI: 10.1021/Jo00168A048 |
0.323 |
|
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