Larisa Poluektova - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Neuroscience Biology, Pathology, Mental Health

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhang C, Su H, Waight E, Poluektova LY, Gorantla S, Gendelman HE, Dash PK. Accelerated Neuroimmune Dysfunction in Aged HIV-1-Infected Humanized Mice. Pharmaceuticals (Basel, Switzerland). 17. PMID 38399364 DOI: 10.3390/ph17020149  0.508
2023 Curley P, Hobson JJ, Liptrott NJ, Makarov E, Al-Khouja A, Tatham L, David CAW, Box H, Neary M, Sharp J, Pertinez H, Meyers D, Flexner C, Freel Meyers CL, Poluektova L, et al. Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations. Pharmaceutics. 15. PMID 37514020 DOI: 10.3390/pharmaceutics15071835  0.324
2023 Zhang C, Zaman LA, Poluektova LY, Gorantla S, Gendelman HE, Dash PK. Humanized Mice for Studies of HIV-1 Persistence and Elimination. Pathogens (Basel, Switzerland). 12. PMID 37513726 DOI: 10.3390/pathogens12070879  0.518
2023 Osna NA, Poluektova LY. Elucidating the role of extracellular vesicles in liver injury induced by HIV. Expert Review of Gastroenterology & Hepatology. PMID 37378531 DOI: 10.1080/17474124.2023.2230867  0.31
2023 Dash PK, Chen C, Kaminski R, Su H, Mancuso P, Sillman B, Zhang C, Liao S, Sravanam S, Liu H, Waight E, Guo L, Mathews S, Sariyer R, Mosley RL, ... Poluektova LY, et al. CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217887120. PMID 37126704 DOI: 10.1073/pnas.2217887120  0.529
2023 New-Aaron M, Koganti SS, Ganesan M, Kanika S, Kumar V, Wang W, Makarov E, Kharbanda KK, Poluektova LY, Osna NA. Hepatocyte-Specific Triggering of Hepatic Stellate Cell Profibrotic Activation by Apoptotic Bodies: The Role of Hepatoma-Derived Growth Factor, HIV, and Ethanol. International Journal of Molecular Sciences. 24. PMID 36982417 DOI: 10.3390/ijms24065346  0.393
2022 New-Aaron M, Dagur RS, Koganti SS, Ganesan M, Wang W, Makarov E, Ogunnaike M, Kharbanda KK, Poluektova LY, Osna NA. Alcohol and HIV-Derived Hepatocyte Apoptotic Bodies Induce Hepatic Stellate Cell Activation. Biology. 11. PMID 36101437 DOI: 10.3390/biology11071059  0.398
2022 Waight E, Zhang C, Mathews S, Kevadiya BD, Lloyd KCK, Gendelman HE, Gorantla S, Poluektova LY, Dash PK. Animal models for studies of HIV-1 brain reservoirs. Journal of Leukocyte Biology. PMID 36044375 DOI: 10.1002/JLB.5VMR0322-161R  0.521
2021 Su H, Sravanam S, Sillman B, Waight E, Makarov E, Mathews S, Poluektova LY, Gorantla S, Gendelman HE, Dash PK. Recovery of Latent HIV-1 from Brain Tissue by Adoptive Cell Transfer in Virally Suppressed Humanized Mice. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 34528173 DOI: 10.1007/s11481-021-10011-w  0.52
2021 Dash PK, Gorantla S, Poluektova L, Hasan M, Waight E, Zhang C, Markovic M, Edagwa B, Machhi J, Olson KE, Wang X, Mosley RL, Kevadiya B, Gendelman HE. Humanized Mice for Infectious and Neurodegenerative disorders. Retrovirology. 18: 13. PMID 34090462 DOI: 10.1186/s12977-021-00557-1  0.321
2021 New-Aaron M, Ganesan M, Dagur RS, Kharbanda KK, Poluektova LY, Osna NA. Pancreatogenic Diabetes: Triggering Effects of Alcohol and HIV. Biology. 10. PMID 33546230 DOI: 10.3390/biology10020108  0.353
2021 Dagur RS, New-Aaron M, Ganesan M, Wang W, Romanova S, Kidambi S, Kharbanda KK, Poluektova LY, Osna NA. Alcohol-and-HIV-Induced Lysosomal Dysfunction Regulates Extracellular Vesicles Secretion and in Liver-Humanized Mice. Biology. 10. PMID 33466299 DOI: 10.3390/biology10010029  0.335
2020 New-Aaron M, Ganesan M, Dagur RS, Kharbanda KK, Poluektova LY, Osna NA. Obeticholic acid attenuates human immunodeficiency virus/alcohol metabolism-induced pro-fibrotic activation in liver cells. World Journal of Hepatology. 12: 965-975. PMID 33312422 DOI: 10.4254/wjh.v12.i11.965  0.397
2020 Dash PK, Alomar FA, Hackfort BT, Su H, Conaway A, Poluektova LY, Gendelman HE, Gorantla S, Bidasee KR. HIV-1-Associated Left Ventricular Cardiac Dysfunction in Humanized Mice. Scientific Reports. 10: 9746. PMID 32546795 DOI: 10.1038/S41598-020-65943-9  0.451
2020 Wang W, Smith N, Makarov E, Sun Y, Gebhart CL, Ganesan M, Osna NA, Gendelman HE, Edagwa BJ, Poluektova LY. A long-acting 3TC ProTide nanoformulation suppresses HBV replication in humanized mice. Nanomedicine : Nanotechnology, Biology, and Medicine. 102185. PMID 32217146 DOI: 10.1016/J.Nano.2020.102185  0.354
2020 Su H, Sravanam S, Gorantla S, Kaminski R, Khalili K, Poluektova L, Gendelman HE, Dash PK. Amplification of Replication Competent HIV-1 by Adoptive Transfer of Human Cells From Infected Humanized Mice. Frontiers in Cellular and Infection Microbiology. 10: 38. PMID 32117811 DOI: 10.3389/Fcimb.2020.00038  0.48
2019 Akkina R, Barber DL, Bility MT, Bissig KD, Burwitz BJ, Eichelberg K, Endsley JJ, Garcia JV, Hafner R, Karakousis PC, Korba BE, Koshy R, Lambros C, Menne S, Nuermberger EL, ... ... Poluektova LY, et al. Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop. Current Hiv Research. PMID 31870268 DOI: 10.2174/1570162X18666191223114019  0.361
2019 Ganesan M, New-Aaron M, Dagur RS, Makarov E, Wang W, Kharbanda KK, Kidambi S, Poluektova LY, Osna NA. Alcohol Metabolism Potentiates HIV-Induced Hepatotoxicity: Contribution to End-Stage Liver Disease. Biomolecules. 9. PMID 31835520 DOI: 10.3390/biom9120851  0.435
2019 Dagur RS, Wang W, Makarov E, Sun Y, Poluektova LY. Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis. Journal of Visualized Experiments : Jove. PMID 31566621 DOI: 10.3791/58645  0.454
2019 Dash PK, Kaminski R, Bella R, Su H, Mathews S, Ahooyi TM, Chen C, Mancuso P, Sariyer R, Ferrante P, Donadoni M, Robinson JA, Sillman B, Lin Z, Hilaire JR, ... ... Poluektova LY, et al. Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice. Nature Communications. 10: 2753. PMID 31266936 DOI: 10.1038/S41467-019-10366-Y  0.489
2019 Zhao R, Li Y, Gorantla S, Poluektova LY, Lin H, Gao F, Wang H, Zhao J, Zheng JC, Huang Y. Small molecule ONC201 inhibits HIV-1 replication in macrophages via FOXO3a and TRAIL. Antiviral Research. PMID 31158413 DOI: 10.1016/J.Antiviral.2019.05.015  0.502
2019 Su H, Cheng Y, Sravanam S, Mathews S, Gorantla S, Poluektova LY, Dash PK, Gendelman HE. Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice. Frontiers in Immunology. 10: 340. PMID 30873181 DOI: 10.3389/Fimmu.2019.00340  0.544
2019 Mathews S, Branch Woods A, Katano I, Makarov E, Thomas MB, Gendelman HE, Poluektova LY, Ito M, Gorantla S. Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice. Molecular Neurodegeneration. 14: 12. PMID 30832693 DOI: 10.1186/S13024-019-0311-Y  0.524
2019 Ganesan M, Poluektova LY, Kharbanda KK, Osna NA. Human immunodeficiency virus and hepatotropic viruses co-morbidities as the inducers of liver injury progression. World Journal of Gastroenterology. 25: 398-410. PMID 30700937 DOI: 10.3748/wjg.v25.i4.398  0.412
2019 Dagur RS, Branch-Woods A, Mathews S, Joshi PS, Quadros RM, Harms DW, Cheng Y, Miles SM, Pirruccello SJ, Gurumurthy CB, Gorantla S, Poluektova LY. Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection. Bmc Immunology. 20: 2. PMID 30616506 DOI: 10.1186/s12865-018-0279-3  0.414
2018 Ganesan M, Poluektova LY, Kharbanda KK, Osna NA. Liver as a target of human immunodeficiency virus infection. World Journal of Gastroenterology. 24: 4728-4737. PMID 30479460 DOI: 10.3748/wjg.v24.i42.4728  0.458
2018 Ganesan M, Dagur RS, Makarov E, Poluektova LI, Kidambi S, Osna NA. Matrix stiffness regulate apoptotic cell death in HIV-HCV co-infected hepatocytes: Importance for liver fibrosis progression. Biochemical and Biophysical Research Communications. PMID 29679566 DOI: 10.1016/j.bbrc.2018.04.142  0.351
2018 Olson KE, Bade AN, Namminga KL, Potash MJ, Mosley RL, Poluektova LY, Volsky DJ, Gendelman HE. Persistent EcoHIV infection induces nigral degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice. Journal of Neurovirology. PMID 29594983 DOI: 10.1007/S13365-018-0629-1  0.471
2018 McMillan JM, Cobb DA, Lin Z, Banoub MG, Dagur RS, Branch Woods AA, Wang W, Makarov E, Kocher T, Joshi PS, Quadros RM, Harms DW, Cohen SM, Gendelman HE, Gurumurthy CB, ... ... Poluektova LY, et al. Antiretroviral drug metabolism in humanized PXR-CAR-CYP3A-NOG mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 29476044 DOI: 10.1124/Jpet.117.247288  0.338
2018 Sillman B, Bade AN, Dash PK, Bhargavan B, Kocher T, Mathews S, Su H, Kanmogne GD, Poluektova LY, Gorantla S, McMillan J, Gautam N, Alnouti Y, Edagwa B, Gendelman HE. Creation of a long-acting nanoformulated dolutegravir. Nature Communications. 9: 443. PMID 29402886 DOI: 10.1038/S41467-018-02885-X  0.42
2018 Dagur RS, Wang W, Cheng Y, Makarov E, Ganesan M, Suemizu H, Gebhart CL, Gorantla S, Osna N, Poluektova LY. Human hepatocytes depletion in the presence of HIV-1 infection in dual reconstituted humanized mice. Biology Open. PMID 29361613 DOI: 10.1242/bio.029785  0.527
2018 Su H, Dash P, Gorantla S, Poluektova L, Gendelman H. P-A8 Establishing tissue reservoirs for the human immunodeficiency virus in humanized mice Journal of Acquired Immune Deficiency Syndromes. 77: 55. DOI: 10.1097/01.Qai.0000532494.94287.Dd  0.362
2017 Li W, Gorantla S, Gendelman HE, Poluektova LY. Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains. Disease Models & Mechanisms. PMID 29084769 DOI: 10.1242/Dmm.031773  0.468
2017 Zhou T, Su H, Dash P, Lin Z, Dyavar Shetty BL, Kocher T, Szlachetka A, Lamberty B, Fox HS, Poluektova L, Gorantla S, McMillan J, Gautam N, Mosley RL, Alnouti Y, et al. Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles. Biomaterials. 151: 53-65. PMID 29059541 DOI: 10.1016/J.Biomaterials.2017.10.023  0.46
2017 Singh VB, Singh MV, Piekna-Przybylska D, Gorantla S, Poluektova LY, Maggirwar SB. Sonic Hedgehog mimetic prevents leukocyte infiltration into the CNS during acute HIV infection. Scientific Reports. 7: 9578. PMID 28852071 DOI: 10.1038/S41598-017-10241-0  0.52
2017 Araínga M, Edagwa B, Mosley RL, Poluektova LY, Gorantla S, Gendelman HE. A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy. Retrovirology. 14: 17. PMID 28279181 DOI: 10.1186/S12977-017-0344-7  0.515
2017 Su H, Dash P, Arainga M, Edagwa B, Mcmillan J, Poluektova L, Gorantla S, Gendelman H. P-D4 Evaluation of Combination Long-Acting Nanoformulated Antiretroviral Therapy in HIV-1 Infected huPBL NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ MICE Journal of Acquired Immune Deficiency Syndromes. 74: 90. DOI: 10.1097/01.Qai.0000513994.51387.74  0.473
2016 Singh VB, Singh MV, Gorantla S, Poluektova LY, Maggirwar SB. Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice. Scientific Reports. 6: 26876. PMID 27241024 DOI: 10.1038/Srep26876  0.494
2016 Araínga M, Su H, Poluektova LY, Gorantla S, Gendelman HE. HIV-1 cellular and tissue replication patterns in infected humanized mice. Scientific Reports. 6: 23513. PMID 26996968 DOI: 10.1038/Srep23513  0.516
2015 Akkina RK, Allam A, Balazs AB, Blankson J, Burnett JC, Casares S, Garcia JV, Hasenkrug K, Kashanchi F, Kitchen S, Klein F, Kumar P, Luster AD, Poluektova LY, Rao M, et al. Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary. Aids Research and Human Retroviruses. PMID 26670361 DOI: 10.1089/Aid.2015.0258  0.445
2015 Zhang G, Guo D, Dash PK, Araínga M, Wiederin JL, Haverland NA, Knibbe-Hollinger J, Martinez-Skinner A, Ciborowski P, Goodfellow VS, Wysocki TA, Wysocki BJ, Poluektova LY, Liu XM, McMillan JM, et al. The Mixed Lineage Kinase-3 Inhibitor URMC-099 Improves Therapeutic Outcomes for Long-Acting Antiretroviral Therapy. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26472049 DOI: 10.1016/J.Nano.2015.09.009  0.413
2015 Bade AN, Gorantla S, Dash PK, Makarov E, Sajja BR, Poluektova LY, Luo J, Gendelman HE, Boska MD, Liu Y. Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice. Molecular Neurobiology. PMID 26063593 DOI: 10.1007/S12035-015-9258-3  0.51
2015 Puligujja P, Araínga M, Dash P, Palandri D, Mosley RL, Gorantla S, Poluektova L, McMillan J, Gendelman HE. Pharmacodynamics of folic acid receptor targeted antiretroviral nanotherapy in HIV-1-infected humanized mice. Antiviral Research. 120: 85-8. PMID 26026666 DOI: 10.1016/J.Antiviral.2015.05.009  0.454
2014 Boska MD, Dash PK, Knibbe J, Epstein AA, Akhter SP, Fields N, High R, Makarov E, Bonasera S, Gelbard HA, Poluektova LY, Gendelman HE, Gorantla S. Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice. Molecular Neurodegeneration. 9: 58. PMID 25523827 DOI: 10.1186/1750-1326-9-58  0.524
2014 Planque SA, Mitsuda Y, Chitsazzadeh V, Gorantla S, Poluektova L, Nishiyama Y, Ochsenbauer C, Morris MK, Sapparapu G, Hanson CV, Massey RJ, Paul S. Deficient synthesis of class-switched, HIV-neutralizing antibodies to the CD4 binding site and correction by electrophilic gp120 immunogen. Aids (London, England). 28: 2201-11. PMID 25022597 DOI: 10.1097/Qad.0000000000000392  0.342
2014 Gerson T, Makarov E, Senanayake TH, Gorantla S, Poluektova LY, Vinogradov SV. Nano-NRTIs demonstrate low neurotoxicity and high antiviral activity against HIV infection in the brain. Nanomedicine : Nanotechnology, Biology, and Medicine. 10: 177-85. PMID 23845925 DOI: 10.1016/j.nano.2013.06.012  0.451
2013 Epstein AA, Narayanasamy P, Dash PK, High R, Bathena SP, Gorantla S, Poluektova LY, Alnouti Y, Gendelman HE, Boska MD. Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 1224-38. PMID 23702663 DOI: 10.1007/S11481-013-9461-9  0.459
2013 Zhang J, Mulvenon A, Makarov E, Wagoner J, Knibbe J, Kim JO, Osna N, Bronich TK, Poluektova LY. Antiviral peptide nanocomplexes as a potential therapeutic modality for HIV/HCV co-infection. Biomaterials. 34: 3846-57. PMID 23403120 DOI: 10.1016/J.Biomaterials.2013.01.026  0.342
2012 Dash PK, Gendelman HE, Roy U, Balkundi S, Alnouti Y, Mosley RL, Gelbard HA, McMillan J, Gorantla S, Poluektova LY. Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice. Aids (London, England). 26: 2135-44. PMID 22824628 DOI: 10.1097/Qad.0B013E328357F5Ad  0.464
2012 Roy U, McMillan J, Alnouti Y, Gautum N, Smith N, Balkundi S, Dash P, Gorantla S, Martinez-Skinner A, Meza J, Kanmogne G, Swindells S, Cohen SM, Mosley RL, Poluektova L, et al. Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1-infected human peripheral blood lymphocyte-reconstituted mice. The Journal of Infectious Diseases. 206: 1577-88. PMID 22811299 DOI: 10.1093/Infdis/Jis395  0.418
2012 Kanmogne GD, Singh S, Roy U, Liu X, McMillan J, Gorantla S, Balkundi S, Smith N, Alnouti Y, Gautam N, Zhou Y, Poluektova L, Kabanov A, Bronich T, Gendelman HE. Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells. International Journal of Nanomedicine. 7: 2373-88. PMID 22661891 DOI: 10.2147/Ijn.S29454  0.372
2012 Gorantla S, Poluektova L, Gendelman HE. Rodent models for HIV-associated neurocognitive disorders. Trends in Neurosciences. 35: 197-208. PMID 22305769 DOI: 10.1016/J.Tins.2011.12.006  0.467
2012 Gorantla S, Gendelman HE, Poluektova LY. Can humanized mice reflect the complex pathobiology of HIV-associated neurocognitive disorders? Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 352-62. PMID 22222956 DOI: 10.1007/S11481-011-9335-Y  0.526
2012 Yannam GR, Gutti T, Poluektova LY. IL-23 in infections, inflammation, autoimmunity and cancer: possible role in HIV-1 and AIDS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 95-112. PMID 21947740 DOI: 10.1007/s11481-011-9315-2  0.388
2011 Dash PK, Gorantla S, Gendelman HE, Knibbe J, Casale GP, Makarov E, Epstein AA, Gelbard HA, Boska MD, Poluektova LY. Loss of neuronal integrity during progressive HIV-1 infection of humanized mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3148-57. PMID 21368026 DOI: 10.1523/Jneurosci.5473-10.2011  0.47
2010 Gorantla S, Makarov E, Finke-Dwyer J, Castanedo A, Holguin A, Gebhart CL, Gendelman HE, Poluektova L. Links between progressive HIV-1 infection of humanized mice and viral neuropathogenesis. The American Journal of Pathology. 177: 2938-49. PMID 21088215 DOI: 10.2353/Ajpath.2010.100536  0.542
2010 Vinogradov SV, Poluektova LY, Makarov E, Gerson T, Senanayake MT. Nano-NRTIs: efficient inhibitors of HIV type-1 in macrophages with a reduced mitochondrial toxicity. Antiviral Chemistry & Chemotherapy. 21: 1-14. PMID 21045256 DOI: 10.3851/IMP1680  0.41
2010 Gorantla S, Makarov E, Roy D, Finke-Dwyer J, Murrin LC, Gendelman HE, Poluektova L. Immunoregulation of a CB2 receptor agonist in a murine model of neuroAIDS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 456-68. PMID 20549374 DOI: 10.1007/S11481-010-9225-8  0.546
2010 Gorantla S, Makarov E, Finke-Dwyer J, Gebhart CL, Domm W, Dewhurst S, Gendelman HE, Poluektova LY. CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 7082-91. PMID 20495069 DOI: 10.4049/Jimmunol.1000438  0.465
2010 Eggert D, Dash PK, Gorantla S, Dou H, Schifitto G, Maggirwar SB, Dewhurst S, Poluektova L, Gelbard HA, Gendelman HE. Neuroprotective activities of CEP-1347 in models of neuroAIDS. Journal of Immunology (Baltimore, Md. : 1950). 184: 746-56. PMID 19966207 DOI: 10.4049/Jimmunol.0902962  0.559
2010 Makarov E, Gerson T, Senanayake T, Poluektova L, Vinogradov S. Efficient Suppression of Human Immunodeficiency Virus in Macrophages by Nano-NRTIs Antiviral Research. 86. DOI: 10.1016/J.Antiviral.2010.02.388  0.389
2009 Eggert D, Dash PK, Serradji N, Dong CZ, Clayette P, Heymans F, Dou H, Gorantla S, Gelbard HA, Poluektova L, Gendelman HE. Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders. Journal of Neuroimmunology. 213: 47-59. PMID 19541372 DOI: 10.1016/J.Jneuroim.2009.06.002  0.399
2008 Gorantla S, Liu J, Wang T, Holguin A, Sneller HM, Dou H, Kipnis J, Poluektova L, Gendelman HE. Modulation of innate immunity by copolymer-1 leads to neuroprotection in murine HIV-1 encephalitis. Glia. 56: 223-32. PMID 18046731 DOI: 10.1002/Glia.20607  0.602
2007 Gorantla S, Liu J, Sneller H, Dou H, Holguin A, Smith L, Ikezu T, Volsky DJ, Poluektova L, Gendelman HE. Copolymer-1 induces adaptive immune anti-inflammatory glial and neuroprotective responses in a murine model of HIV-1 encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 4345-56. PMID 17878329 DOI: 10.4049/Jimmunol.179.7.4345  0.554
2007 Gorantla S, Sneller H, Walters L, Sharp JG, Pirruccello SJ, West JT, Wood C, Dewhurst S, Gendelman HE, Poluektova L. Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice. Journal of Virology. 81: 2700-12. PMID 17182671 DOI: 10.1128/Jvi.02010-06  0.519
2006 Persidsky Y, Poluektova L. Immune privilege and HIV-1 persistence in the CNS. Immunological Reviews. 213: 180-94. PMID 16972904 DOI: 10.1111/J.1600-065X.2006.00440.X  0.529
2006 Dou H, Destache CJ, Morehead JR, Mosley RL, Boska MD, Kingsley J, Gorantla S, Poluektova L, Nelson JA, Chaubal M, Werling J, Kipp J, Rabinow BE, Gendelman HE. Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery. Blood. 108: 2827-35. PMID 16809617 DOI: 10.1182/Blood-2006-03-012534  0.372
2005 Dou H, Ellison B, Bradley J, Kasiyanov A, Poluektova LY, Xiong H, Maggirwar S, Dewhurst S, Gelbard HA, Gendelman HE. Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8375-85. PMID 16162919 DOI: 10.1523/Jneurosci.2164-05.2005  0.352
2005 Poluektova L, Meyer V, Walters L, Paez X, Gendelman HE. Macrophage-induced inflammation affects hippocampal plasticity and neuronal development in a murine model of HIV-1 encephalitis. Glia. 52: 344-53. PMID 16078235 DOI: 10.1002/Glia.20253  0.525
2005 Potula R, Poluektova L, Knipe B, Chrastil J, Heilman D, Dou H, Takikawa O, Munn DH, Gendelman HE, Persidsky Y. Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. Blood. 106: 2382-90. PMID 15961516 DOI: 10.1182/Blood-2005-04-1403  0.583
2005 Gorantla S, Santos K, Meyer V, Dewhurst S, Bowers WJ, Federoff HJ, Gendelman HE, Poluektova L. Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge. Journal of Virology. 79: 2124-32. PMID 15681415 DOI: 10.1128/Jvi.79.4.2124-2132.2005  0.528
2004 Poluektova L, Gorantla S, Faraci J, Birusingh K, Dou H, Gendelman HE. Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: studies in a murine model of viral encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 172: 7610-7. PMID 15187141 DOI: 10.4049/Jimmunol.172.12.7610  0.579
2004 Carlson KA, Limoges J, Pohlman GD, Poluektova LY, Langford D, Masliah E, Ikezu T, Gendelman HE. OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis. Journal of Neuroimmunology. 150: 186-98. PMID 15081264 DOI: 10.1016/J.Jneuroim.2004.01.021  0.468
2004 Boska MD, Mosley RL, Nawab M, Nelson JA, Zelivyanskaya M, Poluektova L, Uberti M, Dou H, Lewis TB, Gendelman HE. Advances in neuroimaging for HIV-1 associated neurological dysfunction: clues to the diagnosis, pathogenesis and therapeutic monitoring. Current Hiv Research. 2: 61-78. PMID 15053341 DOI: 10.2174/1570162043485095  0.474
2004 Nukuna A, Gendelman HE, Limoges J, Rasmussen J, Poluektova L, Ghorpade A, Persidsky Y. Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis. Journal of Neurovirology. 10: 82-90. PMID 14982744 DOI: 10.1080/753312757  0.502
2003 Dou H, Birusingh K, Faraci J, Gorantla S, Poluektova LY, Maggirwar SB, Dewhurst S, Gelbard HA, Gendelman HE. Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9162-70. PMID 14534250 DOI: 10.1523/Jneurosci.23-27-09162.2003  0.477
2002 Poluektova LY, Munn DH, Persidsky Y, Gendelman HE. Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 168: 3941-9. PMID 11937550 DOI: 10.4049/Jimmunol.168.8.3941  0.547
2000 Limoges J, Persidsky Y, Poluektova L, Rasmussen J, Ratanasuwan W, Zelivyanskaya M, McClernon DR, Lanier ER, Gendelman HE. Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice. Neurology. 54: 379-89. PMID 10668699 DOI: 10.1212/Wnl.54.2.379  0.593
1999 Zink WE, Zheng J, Persidsky Y, Poluektova L, Gendelman HE. The neuropathogenesis of HIV-1 infection. Fems Immunology and Medical Microbiology. 26: 233-41. PMID 10575134 DOI: 10.1111/J.1574-695X.1999.Tb01394.X  0.546
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