| Year |
Citation |
Score |
| 2024 |
Ge J, Ngo LP, Kaushal S, Tay IJ, Thadhani E, Kay JE, Mazzucato P, Chow D, Fessler J, Weingeist DM, Sobol RW, Samson LD, Floyd SR, Engelward BP. CometChip enables parallel analysis of multiple DNA repair activities [DNA repair 106 (2021) 103176-103202]. Dna Repair. 138: 103677. PMID 38582050 DOI: 10.1016/j.dnarep.2024.103677 |
0.501 |
|
| 2024 |
Bordin DL, Grooms K, Montaldo NP, Fordyce Martin SL, Sætrom P, Samson LD, Bjørås M, van Loon B. Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory. Dna Repair. 135: 103632. PMID 38280242 DOI: 10.1016/j.dnarep.2024.103632 |
0.458 |
|
| 2023 |
Armijo AL, Thongararm P, Fedeles BI, Yau J, Kay JE, Corrigan JJ, Chancharoen M, Chawanthayatham S, Samson LD, Carrasco SE, Engelward BP, Fox JG, Croy RG, Essigmann JM. Molecular origins of mutational spectra produced by the environmental carcinogen -nitrosodimethylamine and S1 chemotherapeutic agents. Nar Cancer. 5: zcad015. PMID 36992846 DOI: 10.1093/narcan/zcad015 |
0.322 |
|
| 2022 |
Milano L, Charlier CF, Andreguetti R, Cox T, Healing E, Thomé MP, Elliott RM, Samson LD, Masson JY, Lenz G, Henriques JAP, Nohturfft A, Meira LB. A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35197283 DOI: 10.1073/pnas.2111404119 |
0.495 |
|
| 2021 |
Ge J, Ngo LP, Kaushal S, Tay IJ, Thadhani E, Kay JE, Mazzucato P, Chow DN, Fessler JL, Weingeist DM, Sobol RW, Samson LD, Floyd SR, Engelward BP. CometChip enables parallel analysis of multiple DNA repair activities. Dna Repair. 106: 103176. PMID 34365116 DOI: 10.1016/j.dnarep.2021.103176 |
0.536 |
|
| 2021 |
Ngo LP, Kaushal S, Chaim IA, Mazzucato P, Ricciardi C, Samson LD, Nagel ZD, Engelward BP. CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of DNA oxidation damage. Free Radical Biology & Medicine. PMID 34324980 DOI: 10.1016/j.freeradbiomed.2021.07.033 |
0.503 |
|
| 2021 |
Kay JE, Corrigan JJ, Armijo AL, Nazari IS, Kohale IN, Torous DK, Avlasevich SL, Croy RG, Wadduwage DN, Carrasco SE, Dertinger SD, White FM, Essigmann JM, Samson LD, Engelward BP. Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice. Cell Reports. 34: 108864. PMID 33730582 DOI: 10.1016/j.celrep.2021.108864 |
0.477 |
|
| 2019 |
Ngo LP, Owiti NA, Swartz C, Winters J, Su Y, Ge J, Xiong A, Han J, Recio L, Samson LD, Engelward BP. Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates. Nucleic Acids Research. PMID 31822921 DOI: 10.1093/Nar/Gkz1077 |
0.539 |
|
| 2019 |
Montaldo NP, Bordin DL, Brambilla A, Rösinger M, Fordyce Martin SL, Bjørås KØ, Bradamante S, Aas PA, Furrer A, Olsen LC, Kunath N, Otterlei M, Sætrom P, Bjørås M, Samson LD, et al. Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications. 10: 5460. PMID 31784530 DOI: 10.1038/S41467-019-13394-W |
0.507 |
|
| 2019 |
Kay J, Thadhani E, Samson L, Engelward B. Inflammation-induced DNA damage, mutations and cancer. Dna Repair. 102673. PMID 31387777 DOI: 10.1016/J.Dnarep.2019.102673 |
0.572 |
|
| 2019 |
Navasumrit P, Chaisatra K, Promvijit J, Parnlob V, Waraprasit S, Chompoobut C, Binh TT, Hai DN, Bao ND, Hai NK, Kim KW, Samson LD, Graziano JH, Mahidol C, Ruchirawat M. Correction to: Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study. Environmental Health : a Global Access Science Source. 18: 68. PMID 31340827 DOI: 10.1186/S12940-019-0504-4 |
0.416 |
|
| 2019 |
Navasumrit P, Chaisatra K, Promvijit J, Parnlob V, Waraprasit S, Chompoobut C, Binh TT, Hai DN, Bao ND, Hai NK, Kim KW, Samson LD, Graziano JH, Mahidol C, Ruchirawat M. Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study. Environmental Health : a Global Access Science Source. 18: 51. PMID 31174534 DOI: 10.1186/S12940-019-0481-7 |
0.336 |
|
| 2019 |
Nagel ZD, Beharry AA, Mazzucato P, Kitange GJ, Sarkaria JN, Kool ET, Samson LD. Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells. Plos One. 14: e0208341. PMID 30811507 DOI: 10.1371/Journal.Pone.0208341 |
0.479 |
|
| 2019 |
Wilson MR, Jiang Y, Villalta PW, Stornetta A, Boudreau PD, Carrá A, Brennan CA, Chun E, Ngo L, Samson LD, Engelward BP, Garrett WS, Balbo S, Balskus EP. The human gut bacterial genotoxin colibactin alkylates DNA. Science (New York, N.Y.). 363. PMID 30765538 DOI: 10.1126/Science.Aar7785 |
0.552 |
|
| 2019 |
Allocca M, Corrigan JJ, Mazumder A, Fake KR, Samson LD. Inflammation, necrosis, and the kinase RIP3 are key mediators of AAG-dependent alkylation-induced retinal degeneration. Science Signaling. 12. PMID 30755477 DOI: 10.1126/Scisignal.Aau9216 |
0.476 |
|
| 2018 |
Parrish MC, Chaim IA, Nagel ZD, Tannenbaum SR, Samson LD, Engelward BP. Nitric oxide induced S-nitrosation causes base excision repair imbalance. Dna Repair. 68: 25-33. PMID 29929044 DOI: 10.1016/J.Dnarep.2018.04.008 |
0.522 |
|
| 2018 |
Shen J, Ju Z, Zhao W, Wang L, Peng Y, Ge Z, Nagel ZD, Zou J, Wang C, Kapoor P, Ma X, Ma D, Liang J, Song S, Liu J, ... Samson LD, et al. ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade. Nature Medicine. PMID 29736026 DOI: 10.1038/S41591-018-0012-Z |
0.335 |
|
| 2017 |
Chaim IA, Nagel ZD, Jordan JJ, Mazzucato P, Ngo LP, Samson LD. In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities. Proceedings of the National Academy of Sciences of the United States of America. PMID 29122935 DOI: 10.1073/Pnas.1712032114 |
0.61 |
|
| 2017 |
Allocca M, Corrigan JJ, Fake KR, Calvo JA, Samson LD. PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration. Oncotarget. 8: 68707-68720. PMID 28978150 DOI: 10.18632/Oncotarget.19844 |
0.425 |
|
| 2017 |
Margulies CM, Chaim IA, Mazumder A, Criscione J, Samson LD. Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms. Plos One. 12: e0184619. PMID 28886188 DOI: 10.1371/Journal.Pone.0184619 |
0.545 |
|
| 2017 |
Jordan JJ, Chhim S, Margulies CM, Allocca M, Bronson RT, Klungland A, Samson LD, Fu D. ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage. Cell Death & Disease. 8: e2947. PMID 28726787 DOI: 10.1038/Cddis.2017.343 |
0.578 |
|
| 2017 |
Chaim IA, Gardner A, Wu J, Iyama T, Wilson DM, Samson LD. A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine. Nucleic Acids Research. PMID 28115629 DOI: 10.1093/Nar/Gkx015 |
0.486 |
|
| 2016 |
Nagel ZD, Kitange GJ, Gupta SK, Joughin BA, Chaim IA, Mazzucato P, Lauffenburger DA, Sarkaria JN, Samson LD. DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme. Cancer Research. PMID 27793847 DOI: 10.1158/0008-5472.Can-16-1151 |
0.57 |
|
| 2016 |
Wickramaratne SS, Banda D, Ji S, Manlove AH, Malayappan B, Nuñez NN, Samson LD, Campbell C, David SS, Tretyakova NY. Base Excision Repair of N(6)-Deoxyadenosine Adducts of 1,3-Butadiene. Biochemistry. PMID 27552084 DOI: 10.1021/Acs.Biochem.6B00553 |
0.373 |
|
| 2016 |
Calvo JA, Allocca M, Fake KR, Muthupalani S, Corrigan JJ, Bronson RT, Samson LD. Parp1 protects against Aag-dependent alkylation-induced nephrotoxicity in a sex-dependent manner. Oncotarget. PMID 27391435 DOI: 10.18632/Oncotarget.10440 |
0.488 |
|
| 2016 |
Yu AM, Calvo JA, Muthupalani S, Samson LD. The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury. Oncotarget. PMID 27086921 DOI: 10.18632/Oncotarget.8721 |
0.394 |
|
| 2016 |
Beharry AA, Nagel ZD, Samson LD, Kool ET. Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response. Plos One. 11: e0152684. PMID 27035132 DOI: 10.1371/Journal.Pone.0152684 |
0.495 |
|
| 2015 |
Fu D, Samson LD, Hübscher U, van Loon B. The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants. Dna Repair. 35: 13-18. PMID 26408825 DOI: 10.1016/J.Dnarep.2015.09.008 |
0.689 |
|
| 2015 |
McFaline-Figueroa JL, Braun CJ, Stanciu M, Nagel ZD, Mazzucato P, Sangaraju D, Cerniauskas E, Barford K, Vargas A, Chen Y, Tretyakova N, Lees JA, Hemann MT, White FM, Samson LD. Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide. Cancer Research. PMID 26025730 DOI: 10.1158/0008-5472.Can-14-3616 |
0.328 |
|
| 2014 |
Ebrahimkhani MR, Daneshmand A, Mazumder A, Allocca M, Calvo JA, Abolhassani N, Jhun I, Muthupalani S, Ayata C, Samson LD. Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney. Proceedings of the National Academy of Sciences of the United States of America. 111: E4878-86. PMID 25349415 DOI: 10.1073/Pnas.1413582111 |
0.485 |
|
| 2014 |
Kiraly O, Gong G, Roytman MD, Yamada Y, Samson LD, Engelward BP. DNA glycosylase activity and cell proliferation are key factors in modulating homologous recombination in vivo. Carcinogenesis. 35: 2495-502. PMID 25155011 DOI: 10.1093/Carcin/Bgu177 |
0.572 |
|
| 2014 |
Meira LB, Calvo JA, Shah D, Klapacz J, Moroski-Erkul CA, Bronson RT, Samson LD. Repair of endogenous DNA base lesions modulate lifespan in mice. Dna Repair. 21: 78-86. PMID 24994062 DOI: 10.1016/j.dnarep.2014.05.012 |
0.547 |
|
| 2014 |
Nagel ZD, Chaim IA, Samson LD. Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research. Dna Repair. 19: 199-213. PMID 24780560 DOI: 10.1016/J.Dnarep.2014.03.009 |
0.553 |
|
| 2014 |
Nagel ZD, Margulies CM, Chaim IA, McRee SK, Mazzucato P, Ahmad A, Abo RP, Butty VL, Forget AL, Samson LD. Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 111: E1823-32. PMID 24757057 DOI: 10.1073/Pnas.1401182111 |
0.571 |
|
| 2013 |
Svensson JP, Quirós Pesudo L, McRee SK, Adeleye Y, Carmichael P, Samson LD. Genomic phenotyping by barcode sequencing broadly distinguishes between alkylating agents, oxidizing agents, and non-genotoxic agents, and reveals a role for aromatic amino acids in cellular recovery after quinone exposure. Plos One. 8: e73736. PMID 24040048 DOI: 10.1371/Journal.Pone.0073736 |
0.307 |
|
| 2013 |
Mazumder A, Pesudo LQ, McRee S, Bathe M, Samson LD. Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae. Nucleic Acids Research. 41: 9310-24. PMID 23935119 DOI: 10.1093/Nar/Gkt715 |
0.495 |
|
| 2013 |
Fu D, Jordan JJ, Samson LD. Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis. Genes & Development. 27: 1089-100. PMID 23666923 DOI: 10.1101/Gad.215533.113 |
0.59 |
|
| 2013 |
Calvo JA, Moroski-Erkul CA, Lake A, Eichinger LW, Shah D, Jhun I, Limsirichai P, Bronson RT, Christiani DC, Meira LB, Samson LD. Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1. Plos Genetics. 9: e1003413. PMID 23593019 DOI: 10.1371/Journal.Pgen.1003413 |
0.423 |
|
| 2013 |
van Loon B, Samson LD. Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB). Dna Repair. 12: 177-87. PMID 23290262 DOI: 10.1016/J.Dnarep.2012.11.009 |
0.596 |
|
| 2013 |
Mazumder A, Tummler K, Bathe M, Samson LD. Single-cell analysis of ribonucleotide reductase transcriptional and translational response to DNA damage. Molecular and Cellular Biology. 33: 635-42. PMID 23184665 DOI: 10.1128/Mcb.01020-12 |
0.509 |
|
| 2012 |
Noonan EM, Shah D, Yaffe MB, Lauffenburger DA, Samson LD. O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1237-55. PMID 22892544 DOI: 10.1039/C2Ib20091K |
0.491 |
|
| 2012 |
Calvo JA, Meira LB, Lee CY, Moroski-Erkul CA, Abolhassani N, Taghizadeh K, Eichinger LW, Muthupalani S, Nordstrand LM, Klungland A, Samson LD. DNA repair is indispensable for survival after acute inflammation. The Journal of Clinical Investigation. 122: 2680-9. PMID 22684101 DOI: 10.1172/Jci63338 |
0.565 |
|
| 2012 |
Svensson JP, Fry RC, Wang E, Somoza LA, Samson LD. Identification of novel human damage response proteins targeted through yeast orthology. Plos One. 7: e37368. PMID 22615993 DOI: 10.1371/Journal.Pone.0037368 |
0.465 |
|
| 2012 |
Tentner AR, Lee MJ, Ostheimer GJ, Samson LD, Lauffenburger DA, Yaffe MB. Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress. Molecular Systems Biology. 8: 568. PMID 22294094 DOI: 10.1038/Msb.2012.1 |
0.511 |
|
| 2012 |
Fu D, Calvo JA, Samson LD. Balancing repair and tolerance of DNA damage caused by alkylating agents. Nature Reviews. Cancer. 12: 104-20. PMID 22237395 DOI: 10.1038/Nrc3185 |
0.676 |
|
| 2012 |
Setser JW, Lingaraju GM, Davis CA, Samson LD, Drennan CL. Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase. Biochemistry. 51: 382-90. PMID 22148158 DOI: 10.1021/Bi201484K |
0.564 |
|
| 2012 |
Valiathan C, McFaline JL, Samson LD. A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects. Dna Repair. 11: 92-8. PMID 22133811 DOI: 10.1016/J.Dnarep.2011.11.002 |
0.326 |
|
| 2012 |
Fu D, Samson LD. Direct repair of 3,N(4)-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase. Dna Repair. 11: 46-52. PMID 22079122 DOI: 10.1016/J.Dnarep.2011.10.004 |
0.679 |
|
| 2012 |
Samson LD. Abstract IA17: Developing improved methods to measure human DNA repair capacity Cancer Research. 72. DOI: 10.1158/1538-7445.Csb12-Ia17 |
0.596 |
|
| 2011 |
Kisby G, Palmer V, Lasarev M, Fry R, Iordanov M, Magun E, Samson L, Spencer P. Does the Cycad Genotoxin MAM Implicated in Guam ALS-PDC Induce Disease-Relevant Changes in Mouse Brain that Includes Olfaction? Communicative & Integrative Biology. 4: 731-734. PMID 22446540 DOI: 10.4161/Cib.17603 |
0.345 |
|
| 2011 |
Svensson JP, Pesudo LQ, Fry RC, Adeleye YA, Carmichael P, Samson LD. Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. Bmc Systems Biology. 5: 157. PMID 21978764 DOI: 10.1186/1752-0509-5-157 |
0.458 |
|
| 2011 |
Kisby GE, Fry RC, Lasarev MR, Bammler TK, Beyer RP, Churchwell M, Doerge DR, Meira LB, Palmer VS, Ramos-Crawford AL, Ren X, Sullivan RC, Kavanagh TJ, Samson LD, Zarbl H, et al. The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner. Plos One. 6: e20911. PMID 21731631 DOI: 10.1371/Journal.Pone.0020911 |
0.542 |
|
| 2011 |
Lingaraju GM, Davis CA, Setser JW, Samson LD, Drennan CL. Structural basis for the inhibition of human alkyladenine DNA glycosylase (AAG) by 3,N4-ethenocytosine-containing DNA. The Journal of Biological Chemistry. 286: 13205-13. PMID 21349833 DOI: 10.1074/Jbc.M110.192435 |
0.544 |
|
| 2011 |
Villela I, Heidenreich B, Cheema M, di Martino T, Samson LD, Meira LB. Dissecting the mechanism of DNA damage induced photoreceptor cell death Toxicology. 290: 143. DOI: 10.1016/J.Tox.2011.09.073 |
0.543 |
|
| 2010 |
Braithwaite EK, Kedar PS, Stumpo DJ, Bertocci B, Freedman JH, Samson LD, Wilson SH. DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts. Plos One. 5: e12229. PMID 20805875 DOI: 10.1371/Journal.Pone.0012229 |
0.564 |
|
| 2010 |
Wirtz S, Nagel G, Eshkind L, Neurath MF, Samson LD, Kaina B. Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis. Carcinogenesis. 31: 2111-7. PMID 20732909 DOI: 10.1093/Carcin/Bgq174 |
0.553 |
|
| 2010 |
Klapacz J, Lingaraju GM, Guo HH, Shah D, Moar-Shoshani A, Loeb LA, Samson LD. Frameshift Mutagenesis and Microsatellite Instability Induced by Human Alkyladenine DNA Glycosylase Molecular Cell. 37: 843-853. PMID 20347426 DOI: 10.1016/J.Molcel.2010.01.038 |
0.378 |
|
| 2010 |
Fu D, Brophy JA, Chan CT, Atmore KA, Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD. Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival. Molecular and Cellular Biology. 30: 2449-59. PMID 20308323 DOI: 10.1128/Mcb.01604-09 |
0.712 |
|
| 2009 |
Lee CY, Delaney JC, Kartalou M, Lingaraju GM, Maor-Shoshani A, Essigmann JM, Samson LD. Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG). Biochemistry. 48: 1850-61. PMID 19219989 DOI: 10.1021/Bi8018898 |
0.577 |
|
| 2009 |
Kisby GE, Olivas A, Park T, Churchwell M, Doerge D, Samson LD, Gerson SL, Turker MS. DNA repair modulates the vulnerability of the developing brain to alkylating agents. Dna Repair. 8: 400-12. PMID 19162564 DOI: 10.1016/J.Dnarep.2008.12.002 |
0.44 |
|
| 2009 |
Meira LB, Moroski-Erkul CA, Green SL, Calvo JA, Bronson RT, Shah D, Samson LD. Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 888-93. PMID 19139400 DOI: 10.1073/Pnas.0807030106 |
0.447 |
|
| 2009 |
Klapacz J, Meira LB, Luchetti DG, Calvo JA, Bronson RT, Edelmann W, Samson LD. O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 576-81. PMID 19124772 DOI: 10.1073/Pnas.0811991106 |
0.368 |
|
| 2008 |
Bugni JM, Meira LB, Samson LD. Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins. Oncogene. 28: 734-41. PMID 19029948 DOI: 10.1038/onc.2008.426 |
0.348 |
|
| 2008 |
Erlich RL, Fry RC, Begley TJ, Daee DL, Lahue RS, Samson LD. Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae. Plos One. 3: e3717. PMID 19005567 DOI: 10.1371/Journal.Pone.0003717 |
0.409 |
|
| 2008 |
Fry RC, Svensson JP, Valiathan C, Wang E, Hogan BJ, Bhattacharya S, Bugni JM, Whittaker CA, Samson LD. Genomic predictors of interindividual differences in response to DNA damaging agents. Genes & Development. 22: 2621-6. PMID 18805990 DOI: 10.1101/Gad.1688508 |
0.449 |
|
| 2008 |
Chen CY, Guo HH, Shah D, Blank A, Samson LD, Loeb LA. Substrate binding pocket residues of human alkyladenine-DNA glycosylase critical for methylating agent survival Dna Repair. 7: 1731-1745. PMID 18706524 DOI: 10.1016/J.Dnarep.2008.06.019 |
0.499 |
|
| 2008 |
Maor-Shoshani A, Meira LB, Yang X, Samson LD. 3-Methyladenine DNA glycosylase is important for cellular resistance to psoralen interstrand cross-links. Dna Repair. 7: 1399-406. PMID 18571479 DOI: 10.1016/J.Dnarep.2008.04.017 |
0.551 |
|
| 2008 |
Meira LB, Bugni JM, Green SL, Lee CW, Pang B, Borenshtein D, Rickman BH, Rogers AB, Moroski-Erkul CA, McFaline JL, Schauer DB, Dedon PC, Fox JG, Samson LD. DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. The Journal of Clinical Investigation. 118: 2516-25. PMID 18521188 DOI: 10.1172/Jci35073 |
0.529 |
|
| 2008 |
Ringvoll J, Moen MN, Nordstrand LM, Meira LB, Pang B, Bekkelund A, Dedon PC, Bjelland S, Samson LD, Falnes PØ, Klungland A. AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA. Cancer Research. 68: 4142-9. PMID 18519673 DOI: 10.1158/0008-5472.Can-08-0796 |
0.556 |
|
| 2008 |
Nagasubramanian R, Hansen RJ, Delaney SM, Cherian MM, Samson LD, Kogan SC, Dolan ME. Survival and tumorigenesis in O6-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure. Mutagenesis. 23: 341-6. PMID 18477655 DOI: 10.1093/Mutage/Gen018 |
0.335 |
|
| 2008 |
Lingaraju GM, Kartalou M, Meira LB, Samson LD. Substrate specificity and sequence-dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag). Dna Repair. 7: 970-82. PMID 18472311 DOI: 10.1016/J.Dnarep.2008.03.024 |
0.487 |
|
| 2008 |
Dong L, Meira LB, Hazra TK, Samson LD, Cao W. Oxanine DNA glycosylase activities in mammalian systems. Dna Repair. 7: 128-34. PMID 17954039 DOI: 10.1016/J.Dnarep.2007.09.004 |
0.575 |
|
| 2007 |
Rusyn I, Fry RC, Begley TJ, Klapacz J, Svensson JP, Ambrose M, Samson LD. Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates. Plos One. 2: e1252. PMID 18043759 DOI: 10.1371/Journal.Pone.0001252 |
0.581 |
|
| 2007 |
Burgis NE, Samson LD. The protein degradation response of Saccharomyces cerevisiae to classical DNA-damaging agents. Chemical Research in Toxicology. 20: 1843-53. PMID 18020423 DOI: 10.1021/tx700126e |
0.43 |
|
| 2007 |
Longerich S, Meira L, Shah D, Samson LD, Storb U. Alkyladenine DNA glycosylase (Aag) in somatic hypermutation and class switch recombination. Dna Repair. 6: 1764-73. PMID 17681497 DOI: 10.1016/J.Dnarep.2007.06.012 |
0.518 |
|
| 2007 |
Bugni JM, Han J, Tsai MS, Hunter DJ, Samson LD. Genetic association and functional studies of major polymorphic variants of MGMT. Dna Repair. 6: 1116-26. PMID 17569599 DOI: 10.1016/J.Dnarep.2007.03.023 |
0.439 |
|
| 2007 |
Shuga J, Zhang J, Samson LD, Lodish HF, Griffith LG. In vitro erythropoiesis from bone marrow-derived progenitors provides a physiological assay for toxic and mutagenic compounds. Proceedings of the National Academy of Sciences of the United States of America. 104: 8737-42. PMID 17502613 DOI: 10.1073/Pnas.0701829104 |
0.457 |
|
| 2007 |
Hansen RJ, Nagasubramanian R, Delaney SM, Samson LD, Dolan ME. Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice. Carcinogenesis. 28: 1111-6. PMID 17116724 DOI: 10.1093/Carcin/Bgl218 |
0.365 |
|
| 2006 |
Fry RC, DeMott MS, Cosgrove JP, Begley TJ, Samson LD, Dedon PC. The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA. Bmc Genomics. 7: 313. PMID 17163986 DOI: 10.1186/1471-2164-7-313 |
0.559 |
|
| 2006 |
Han J, Tranah GJ, Hankinson SE, Samson LD, Hunter DJ. Polymorphisms in O6-methylguanine DNA methyltransferase and breast cancer risk. Pharmacogenetics and Genomics. 16: 469-74. PMID 16788379 DOI: 10.1097/01.Fpc.0000215065.21718.4C |
0.353 |
|
| 2006 |
Workman CT, Mak HC, McCuine S, Tagne JB, Agarwal M, Ozier O, Begley TJ, Samson LD, Ideker T. A systems approach to mapping DNA damage response pathways. Science (New York, N.Y.). 312: 1054-9. PMID 16709784 DOI: 10.1126/Science.1122088 |
0.485 |
|
| 2006 |
Tranah GJ, Bugni J, Giovannucci E, Ma J, Fuchs C, Hines L, Samson L, Hunter DJ. O6-methylguanine-DNA methyltransferase Leu84Phe and Ile143Val polymorphisms and risk of colorectal cancer in the Nurses' Health Study and Physicians' Health Study (United States). Cancer Causes & Control : Ccc. 17: 721-31. PMID 16633920 DOI: 10.1007/S10552-006-0005-Y |
0.427 |
|
| 2006 |
Benn JA, Hu J, Hogan BJ, Fry RC, Samson LD, Thorsen T. Comparative modeling and analysis of microfluidic and conventional DNA microarrays. Analytical Biochemistry. 348: 284-93. PMID 16307717 DOI: 10.1016/J.Ab.2005.10.033 |
0.368 |
|
| 2005 |
Delaney JC, Smeester L, Wong C, Frick LE, Taghizadeh K, Wishnok JS, Drennan CL, Samson LD, Essigmann JM. AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo. Nature Structural & Molecular Biology. 12: 855-60. PMID 16200073 DOI: 10.1038/Nsmb996 |
0.507 |
|
| 2005 |
Fry RC, Begley TJ, Samson LD. Genome-wide responses to DNA-damaging agents. Annual Review of Microbiology. 59: 357-77. PMID 16153173 DOI: 10.1146/Annurev.Micro.59.031805.133658 |
0.553 |
|
| 2004 |
Said MR, Begley TJ, Oppenheim AV, Lauffenburger DA, Samson LD. Global network analysis of phenotypic effects: protein networks and toxicity modulation in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 101: 18006-11. PMID 15608068 DOI: 10.1073/Pnas.0405996101 |
0.376 |
|
| 2004 |
Begley TJ, Rosenbach AS, Ideker T, Samson LD. Hot spots for modulating toxicity identified by genomic phenotyping and localization mapping. Molecular Cell. 16: 117-25. PMID 15469827 DOI: 10.1016/J.Molcel.2004.09.005 |
0.363 |
|
| 2004 |
Begley TJ, Samson LD. Reversing DNA damage with a directional bias. Nature Structural & Molecular Biology. 11: 688-90. PMID 15280878 DOI: 10.1038/Nsmb0804-688 |
0.569 |
|
| 2004 |
Begley TJ, Samson LD. Network responses to DNA damaging agents. Dna Repair. 3: 1123-32. PMID 15279801 DOI: 10.1016/J.Dnarep.2004.03.013 |
0.451 |
|
| 2004 |
Hitchcock TM, Dong L, Connor EE, Meira LB, Samson LD, Wyatt MD, Cao W. Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase. The Journal of Biological Chemistry. 279: 38177-83. PMID 15247209 DOI: 10.1074/Jbc.M405882200 |
0.553 |
|
| 2004 |
Sandercock LE, Kwok MC, Luchman HA, Mark SC, Giesbrecht JL, Samson LD, Jirik FR. Mutational-reporter transgenes rescued from mice lacking either Mgmt, or both Mgmt and Msh6 suggest that O6-alkylguanine-induced miscoding does not contribute to the spontaneous mutational spectrum. Oncogene. 23: 5931-40. PMID 15208683 DOI: 10.1038/Sj.Onc.1207791 |
0.416 |
|
| 2004 |
Ham AJ, Engelward BP, Koc H, Sangaiah R, Meira LB, Samson LD, Swenberg JA. New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N6-etheno-deoxyadenosine DNA lesions from lung and liver in vivo. Dna Repair. 3: 257-65. PMID 15177041 DOI: 10.1016/J.Dnarep.2003.11.003 |
0.499 |
|
| 2004 |
Kisby GE, Lesselroth H, Olivas A, Samson L, Gold B, Tanaka K, Turker MS. Role of nucleotide- and base-excision repair in genotoxin-induced neuronal cell death. Dna Repair. 3: 617-27. PMID 15135729 DOI: 10.1016/J.Dnarep.2004.02.005 |
0.376 |
|
| 2004 |
Han J, Colditz GA, Samson LD, Hunter DJ. Polymorphisms in DNA double-strand break repair genes and skin cancer risk. Cancer Research. 64: 3009-13. PMID 15126335 DOI: 10.1158/0008-5472.Can-04-0246 |
0.424 |
|
| 2004 |
Hickman MJ, Samson LD. Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine. Molecular Cell. 14: 105-16. PMID 15068807 DOI: 10.1016/S1097-2765(04)00162-5 |
0.738 |
|
| 2003 |
Hofseth LJ, Khan MA, Ambrose M, Nikolayeva O, Xu-Welliver M, Kartalou M, Hussain SP, Roth RB, Zhou X, Mechanic LE, Zurer I, Rotter V, Samson LD, Harris CC. The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. The Journal of Clinical Investigation. 112: 1887-94. PMID 14679184 DOI: 10.1172/Jci19757 |
0.388 |
|
| 2003 |
Sobol RW, Kartalou M, Almeida KH, Joyce DF, Engelward BP, Horton JK, Prasad R, Samson LD, Wilson SH. Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses. The Journal of Biological Chemistry. 278: 39951-9. PMID 12882965 DOI: 10.1074/Jbc.M306592200 |
0.482 |
|
| 2003 |
Samson LD. On the 50th anniversary of solving the structure of DNA. Environmental Health Perspectives. 111: A329-31. PMID 12790141 DOI: 10.1289/Ehp.111-A329 |
0.455 |
|
| 2003 |
Begley TJ, Samson LD. Molecular biology: A fix for RNA. Nature. 421: 795-6. PMID 12594492 DOI: 10.1038/421795A |
0.455 |
|
| 2003 |
Begley TJ, Samson LD. AlkB mystery solved: oxidative demethylation of N1-methyladenine and N3-methylcytosine adducts by a direct reversal mechanism. Trends in Biochemical Sciences. 28: 2-5. PMID 12517444 DOI: 10.1016/S0968-0004(02)00010-5 |
0.587 |
|
| 2002 |
Plosky B, Samson L, Engelward BP, Gold B, Schlaen B, Millas T, Magnotti M, Schor J, Scicchitano DA. Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes. Dna Repair. 1: 683-96. PMID 12509290 DOI: 10.1016/S1568-7864(02)00075-7 |
0.59 |
|
| 2002 |
Begley TJ, Rosenbach AS, Ideker T, Samson LD. Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping Molecular Cancer Research. 1: 103-112. PMID 12496357 |
0.323 |
|
| 2002 |
Sobol RW, Watson DE, Nakamura J, Yakes FM, Hou E, Horton JK, Ladapo J, Van Houten B, Swenberg JA, Tindall KR, Samson LD, Wilson SH. Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 99: 6860-5. PMID 11983862 DOI: 10.1073/Pnas.092662499 |
0.486 |
|
| 2002 |
Roth RB, Samson LD. 3-Methyladenine DNA glycosylase-deficient Aag null mice display unexpected bone marrow alkylation resistance. Cancer Research. 62: 656-60. PMID 11830515 |
0.338 |
|
| 2000 |
Lau AY, Wyatt MD, Glassner BJ, Samson LD, Ellenberger T. Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proceedings of the National Academy of Sciences of the United States of America. 97: 13573-8. PMID 11106395 DOI: 10.1073/pnas.97.25.13573 |
0.481 |
|
| 2000 |
Kartalou M, Samson LD, Essigmann JM. Cisplatin adducts inhibit 1,N(6)-ethenoadenine repair by interacting with the human 3-methyladenine DNA glycosylase. Biochemistry. 39: 8032-8. PMID 10891085 DOI: 10.1021/Bi000417H |
0.593 |
|
| 2000 |
Wyatt MD, Samson LD. Influence of DNA structure on hypoxanthine and 1,N(6)-ethenoadenine removal by murine 3-methyladenine DNA glycosylase. Carcinogenesis. 21: 901-8. PMID 10783310 DOI: 10.1093/CARCIN/21.5.901 |
0.47 |
|
| 2000 |
Roth RB, Samson LD. Gene transfer to suppress bone marrow alkylation sensitivity. Mutation Research. 462: 107-20. PMID 10767622 DOI: 10.1016/S1383-5742(00)00021-1 |
0.364 |
|
| 1999 |
Posnick LM, Samson LD. Imbalanced base excision repair increases spontaneous mutation and alkylation sensitivity in Escherichia coli. Journal of Bacteriology. 181: 6763-71. PMID 10542179 DOI: 10.1128/JB.181.21.6763-6771.1999 |
0.445 |
|
| 1999 |
Posnick LM, Samson LD. Influence of S-adenosylmethionine pool size on spontaneous mutation, dam methylation, and cell growth of Escherichia coli. Journal of Bacteriology. 181: 6756-62. PMID 10542178 DOI: 10.1128/JB.181.21.6756-6762.1999 |
0.366 |
|
| 1999 |
Hickman MJ, Samson LD. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proceedings of the National Academy of Sciences of the United States of America. 96: 10764-9. PMID 10485900 DOI: 10.1073/Pnas.96.19.10764 |
0.747 |
|
| 1999 |
Wyatt MD, Allan JM, Lau AY, Ellenberger TE, Samson LD. 3-methyladenine DNA glycosylases: structure, function, and biological importance. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 21: 668-76. PMID 10440863 DOI: 10.1002/(SICI)1521-1878(199908)21:8<668::AID-BIES6>3.0.CO;2-D |
0.466 |
|
| 1999 |
Glassner BJ, Weeda G, Allan JM, Broekhof JL, Carls NH, Donker I, Engelward BP, Hampson RJ, Hersmus R, Hickman MJ, Roth RB, Warren HB, Wu MM, Hoeijmakers JH, Samson LD. DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents. Mutagenesis. 14: 339-47. PMID 10375003 DOI: 10.1093/Mutage/14.3.339 |
0.714 |
|
| 1999 |
Jelinsky SA, Samson LD. Global response of Saccharomyces cerevisiae to an alkylating agent. Proceedings of the National Academy of Sciences of the United States of America. 96: 1486-91. PMID 9990050 DOI: 10.1073/PNAS.96.4.1486 |
0.367 |
|
| 1998 |
Glassner BJ, Rasmussen LJ, Najarian MT, Posnick LM, Samson LD. Generation of a strong mutator phenotype in yeast by imbalanced base excision repair. Proceedings of the National Academy of Sciences of the United States of America. 95: 9997-10002. PMID 9707589 DOI: 10.1073/Pnas.95.17.9997 |
0.442 |
|
| 1998 |
Glassner BJ, Posnick LM, Samson LD. The influence of DNA glycosylases on spontaneous mutation. Mutation Research. 400: 33-44. PMID 9685578 DOI: 10.1016/S0027-5107(98)00045-1 |
0.366 |
|
| 1998 |
Jacobs H, Fukita Y, van der Horst GT, de Boer J, Weeda G, Essers J, de Wind N, Engelward BP, Samson L, Verbeek S, de Murcia JM, de Murcia G, te Riele H, Rajewsky K. Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice. The Journal of Experimental Medicine. 187: 1735-43. PMID 9607915 DOI: 10.1084/Jem.187.11.1735 |
0.456 |
|
| 1998 |
Engelward BP, Allan JM, Dreslin AJ, Kelly JD, Wu MM, Gold B, Samson LD. A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome Journal of Biological Chemistry. 273: 5412-5418. PMID 9479003 DOI: 10.1074/jbc.273.9.5412 |
0.519 |
|
| 1997 |
Engelward BP, Weeda G, Wyatt MD, Broekhof JLM, De Wit J, Donker I, Allan JM, Gold B, Hoeijmakers JHJ, Samson LD. Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase Proceedings of the National Academy of Sciences of the United States of America. 94: 13087-13092. PMID 9371804 DOI: 10.1073/Pnas.94.24.13087 |
0.586 |
|
| 1997 |
Samson L, Han S, Marquis JC, Rasmussen LJ. Mammalian DNA repair methyltransferases shield O4MeT from nucleotide excision repair. Carcinogenesis. 18: 919-24. PMID 9163676 DOI: 10.1093/CARCIN/18.5.919 |
0.345 |
|
| 1996 |
Rasmussen LJ, Samson L. The Escherichia coli MutS DNA mismatch binding protein specifically binds O(6)-methylguanine DNA lesions. Carcinogenesis. 17: 2085-8. PMID 8824540 DOI: 10.1093/Carcin/17.9.2085 |
0.614 |
|
| 1996 |
Engelward BP, Dreslin A, Christensen J, Huszar D, Kurahara C, Samson L. Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing. The Embo Journal. 15: 945-952. DOI: 10.1002/j.1460-2075.1996.tb00429.x |
0.442 |
|
| 1995 |
Singh KK, Samson L. Replication protein A binds to regulatory elements in yeast DNA repair and DNA metabolism genes Proceedings of the National Academy of Sciences of the United States of America. 92: 4907-4911. PMID 7761422 DOI: 10.1073/Pnas.92.11.4907 |
0.588 |
|
| 1994 |
Mackay WJ, Han S, Samson LD. DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coli. Journal of Bacteriology. 176: 3224-30. PMID 8195077 DOI: 10.1128/JB.176.11.3224-3230.1994 |
0.4 |
|
| 1993 |
Engelward BP, Boosalis MS, Chen BJ, Deng Z, Siciliano MJ, Samson LD. Cloning and characterization of a mouse 3-methyladenine/7-methyl-guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11. Carcinogenesis. 14: 175-81. PMID 8435858 DOI: 10.1093/Carcin/14.2.175 |
0.545 |
|
| 1993 |
Matijasevic Z, Boosalis M, Mackay W, Samson L, Ludlum DB. Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylase. Proceedings of the National Academy of Sciences of the United States of America. 90: 11855-9. PMID 8265637 DOI: 10.1073/Pnas.90.24.11855 |
0.431 |
|
| 1992 |
Xiao W, Samson L. The Saccharomyces cerevisiae MGT1 DNA repair methyltransferease gene: Its promoter and entire coding sequence, regulation and in vivo biological functions Nucleic Acids Research. 20: 3599-3606. PMID 1641326 DOI: 10.1093/nar/20.14.3599 |
0.413 |
|
| 1992 |
Samson L. The suicidal DNA repair methyltransferases of microbes. Molecular Microbiology. 6: 825-31. PMID 1602962 DOI: 10.1111/j.1365-2958.1992.tb01533.x |
0.515 |
|
| 1991 |
Samson L, Derfler B, Boosalis M, Call K. Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16 Proceedings of the National Academy of Sciences of the United States of America. 88: 9127-9131. PMID 1924375 DOI: 10.1073/PNAS.88.20.9127 |
0.45 |
|
| 1991 |
Xiao W, Derfler B, Chen J, Samson L. Primary sequence and biological functions of a Saccharomyces cerevisiae O6-methylguanine/O4-methylthymine DNA repair methyltransferase gene. The Embo Journal. 10: 2179-2186. DOI: 10.1002/j.1460-2075.1991.tb07753.x |
0.326 |
|
| 1989 |
Chen J, Derfler B, Maskati A, Samson L. Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 86: 7961-7965. PMID 2682633 DOI: 10.1073/Pnas.86.20.7961 |
0.562 |
|
| 1987 |
Samson L, Linn S. DNA alkylation repair and the induction of cell death and sister chromatid exchange in human cells. Carcinogenesis. 8: 227-230. PMID 3802405 DOI: 10.1093/Carcin/8.2.227 |
0.5 |
|
| 1977 |
Samson L, Cairns J. A new pathway for DNA repair in Escherichia coli. Nature. 267: 281-3. PMID 325420 DOI: 10.1038/267281A0 |
0.526 |
|
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