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Zucai Suo - Publications

Affiliations: 
Chemistry and Biochemistry Ohio State University, Columbus, Columbus, OH 
Area:
enzymes involved in DNA/RNA replication, Hepatitis C replication, drug design
Website:
http://chemistry.osu.edu/faculty/suo
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109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chu WT, Suo Z, Wang J. Three-metal ion mechanism of cross-linked and uncross-linked DNA polymerase β: A theoretical study. The Journal of Chemical Physics. 160. PMID 38619457 DOI: 10.1063/5.0200109  0.336
2024 Zhao W, Hussen AS, Freudenthal BD, Suo Z, Zhao L. Mitochondrial transcription factor A (TFAM) has 5'-deoxyribose phosphate lyase activity in vitro. Dna Repair. 137: 103666. PMID 38492429 DOI: 10.1016/j.dnarep.2024.103666  0.464
2022 Kumar A, Reed AJ, Zahurancik WJ, Daskalova SM, Hecht SM, Suo Z. Interlocking activities of DNA polymerase β in the base excision repair pathway. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118940119. PMID 35238634 DOI: 10.1073/pnas.2118940119  0.829
2021 Chu X, Suo Z, Wang J. Investigating the Conformational Dynamics of a Y-Family DNA Polymerase during Its Folding and Binding to DNA and a Nucleotide. Jacs Au. 2: 341-356. PMID 35252985 DOI: 10.1021/jacsau.1c00368  0.529
2021 Raper AT, Maxwell BA, Suo Z. Dynamic processing of a common oxidative DNA lesion by the first two enzymes of the base excision repair pathway. Journal of Molecular Biology. 166811. PMID 33450252 DOI: 10.1016/j.jmb.2021.166811  0.46
2020 Zahurancik WJ, Suo Z. Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ε holoenzyme. The Journal of Biological Chemistry. 295: 17251-17264. PMID 33453973 DOI: 10.1074/jbc.RA120.013903  0.836
2020 Chu X, Suo Z, Wang J. Investigating the trade-off between folding and function in a multidomain Y-family DNA polymerase. Elife. 9. PMID 33079059 DOI: 10.7554/eLife.60434  0.505
2020 Zahurancik WJ, Suo Z. Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase epsilon holoenzyme. The Journal of Biological Chemistry. PMID 33051204 DOI: 10.1074/jbc.RA120.013903  0.834
2020 Galati MA, Hodel KP, Gams MS, Sudhaman S, Bridge T, Zahurancik WJ, Ungerleider NA, Park VS, Ercan AB, Joksimovic L, Siddiqui I, Siddaway R, Edwards M, de Borja R, Elshaer D, ... ... Suo Z, et al. Cancers from novel Pole mutant mouse models provide insights into polymerase-mediated hypermutagenesis and immune checkpoint blockade. Cancer Research. PMID 32938641 DOI: 10.1158/0008-5472.Can-20-0624  0.723
2020 Hodel KP, Sun MJS, Ungerleider N, Park VS, Williams LG, Bauer DL, Immethun VE, Wang J, Suo Z, Lu H, McLachlan JB, Pursell ZF. POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status. Molecular Cell. PMID 32497495 DOI: 10.1016/J.Molcel.2020.05.012  0.357
2020 Chu WT, Suo Z, Wang J. Binding-Induced Conformational Changes Involved in Sliding Clamp PCNA and DNA Polymerase DPO4. Iscience. 23: 101117. PMID 32422591 DOI: 10.1016/J.Isci.2020.101117  0.598
2020 Chu X, Suo Z, Wang J. Confinement and Crowding Effects on Folding of a Multi-domain Y-family DNA Polymerase. Journal of Chemical Theory and Computation. PMID 31972079 DOI: 10.1021/Acs.Jctc.9B01146  0.394
2019 Phi KK, Smith MC, Tokarsky EJ, Suo Z. Kinetic Investigation of Translesion Synthesis across a 3-Nitrobenzanthrone-Derived DNA Lesion Catalyzed by Human DNA Polymerase Kappa. Chemical Research in Toxicology. PMID 31286773 DOI: 10.1021/Acs.Chemrestox.9B00219  0.588
2018 Raper AT, Reed AJ, Suo Z. Kinetic Mechanism of DNA Polymerases: Contributions of Conformational Dynamics and a Third Divalent Metal Ion. Chemical Reviews. PMID 29863852 DOI: 10.1021/Acs.Chemrev.7B00685  0.597
2018 Gadkari VV, Harvey SR, Raper AT, Chu WT, Wang J, Wysocki VH, Suo Z. Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling. Nucleic Acids Research. PMID 29529283 DOI: 10.1093/Nar/Gky125  0.793
2018 Stephenson AA, Raper AT, Suo Z. Bidirectional Degradation of DNA Cleavage Products Catalyzed by CRISPR/Cas9. Journal of the American Chemical Society. PMID 29461055 DOI: 10.1021/Jacs.7B13050  0.587
2018 Raper AT, Stephenson AA, Suo Z. Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9. Journal of the American Chemical Society. PMID 29442507 DOI: 10.1021/Jacs.7B13047  0.584
2018 Kimsey IJ, Szymanski ES, Zahurancik WJ, Shakya A, Xue Y, Chu CC, Sathyamoorthy B, Suo Z, Al-Hashimi HM. Dynamic basis for dG•dT misincorporation via tautomerization and ionization. Nature. 554: 195-201. PMID 29420478 DOI: 10.1038/Nature25487  0.743
2017 Campbell BB, Light N, Fabrizio D, Zatzman M, Fuligni F, de Borja R, Davidson S, Edwards M, Elvin JA, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Wimmer K, Kratz CP, et al. Comprehensive Analysis of Hypermutation in Human Cancer. Cell. PMID 29056344 DOI: 10.1016/J.Cell.2017.09.048  0.746
2017 Reed AJ, Suo Z. Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. Journal of the American Chemical Society. PMID 28682600 DOI: 10.1021/Jacs.7B05048  0.566
2017 Wu J, Wang P, Li L, Williams NL, Ji D, Zahurancik WJ, You C, Wang J, Suo Z, Wang Y. Replication studies of carboxymethylated DNA lesions in human cells. Nucleic Acids Research. PMID 28531304 DOI: 10.1093/Nar/Gkx442  0.82
2017 Prakasha Gowda AS, Krzeminski J, Amin S, Suo Z, Spratt TE. Mutagenic Replication of N(2)-deoxyguanosine benzo[a]pyrene adducts by Escherichia coli DNA polymerase I and Sulfolobus solfataricus DNA polymerase IV. Chemical Research in Toxicology. PMID 28402640 DOI: 10.1021/Acs.Chemrestox.6B00466  0.517
2017 Vyas R, Reed AJ, Raper AT, Zahurancik WJ, Wallenmeyer PC, Suo Z. Structural basis for the D-stereoselectivity of human DNA polymerase β. Nucleic Acids Research. PMID 28402499 DOI: 10.1093/Nar/Gkx252  0.828
2017 Stephenson AA, Taggart DJ, Suo Z. Non-catalytic, N-terminal Domains of DNA Polymerase Lambda Affect Its Cellular Localization and DNA Damage Response. Chemical Research in Toxicology. PMID 28380295 DOI: 10.1021/Acs.Chemrestox.7B00067  0.591
2017 Raper AT, Reed AJ, Gadkari VV, Suo Z. Advances in Structural and Single-Molecule Methods for Investigating DNA Lesion Bypass and Repair Polymerases. Chemical Research in Toxicology. 30: 260-269. PMID 28092942 DOI: 10.1021/Acs.Chemrestox.6B00342  0.851
2017 Gowda P, Suo Z, Spratt TE. Honokiol inhibits DNA polymerases β and λ and increases bleomycin sensitivity of human cancer cells. Chemical Research in Toxicology. PMID 28067485 DOI: 10.1021/Acs.Chemrestox.6B00451  0.579
2016 Tokarsky EJ, Wallenmeyer PC, Phi KK, Suo Z. Significant impact of divalent metal ions on the fidelity, sugar selectivity, and drug incorporation efficiency of human PrimPol. Dna Repair. PMID 27989484 DOI: 10.1016/J.Dnarep.2016.11.003  0.517
2016 Reed AJ, Suo Z, Vyas R, Raper AT. Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase. Journal of the American Chemical Society. PMID 27959534 DOI: 10.1021/Jacs.6B11258  0.597
2016 Lee E, Fowler JD, Suo Z, Wu Z. Backbone assignment of the binary complex of the full length Sulfolobus solfataricus DNA polymerase IV and DNA. Biomolecular Nmr Assignments. PMID 27738883 DOI: 10.1007/S12104-016-9717-4  0.632
2016 Raper AT, Suo Z. Investigation of Intradomain Motions of a Y-Family DNA Polymerase during Substrate Binding and Catalysis. Biochemistry. PMID 27685341 DOI: 10.1021/Acs.Biochem.6B00878  0.64
2016 Tokarsky EJ, Gadkari VV, Zahurancik WJ, Malik CK, Basu AK, Suo Z. Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases. Dna Repair. PMID 27612622 DOI: 10.1016/J.Dnarep.2016.08.002  0.82
2016 Patra A, Politica DA, Chatterjee A, Tokarsky EJ, Suo Z, Basu A, Stone MP, Egli M. Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase. Chembiochem : a European Journal of Chemical Biology. PMID 27556902 DOI: 10.1002/Cbic.201600420  0.575
2016 Raper AT, Gadkari VV, Maxwell BA, Suo Z. Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase. Biochemistry. PMID 27002236 DOI: 10.1021/Acs.Biochem.6B00166  0.861
2015 Vyas R, Efthimiopoulos G, Tokarsky EJ, Malik CK, Basu AK, Suo Z. Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase. Journal of the American Chemical Society. 137: 12131-42. PMID 26327169 DOI: 10.1021/Jacs.5B08027  0.64
2015 Vyas R, Reed AJ, Tokarsky EJ, Suo Z. Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography. Journal of the American Chemical Society. 137: 5225-30. PMID 25825995 DOI: 10.1021/Jacs.5B02109  0.523
2015 Dunn MR, Larsen AC, Zahurancik WJ, Fahmi NE, Meyers M, Suo Z, Chaput JC. DNA polymerase-mediated synthesis of unbiased threose nucleic acid (TNA) polymers requires 7-deazaguanine to suppress G:G mispairing during TNA transcription. Journal of the American Chemical Society. 137: 4014-7. PMID 25785966 DOI: 10.1021/Ja511481N  0.834
2015 Zahurancik WJ, Baranovskiy AG, Tahirov TH, Suo Z. Comparison of the kinetic parameters of the truncated catalytic subunit and holoenzyme of human DNA polymerase ɛ. Dna Repair. 29: 16-22. PMID 25684708 DOI: 10.1016/J.Dnarep.2015.01.008  0.852
2015 Suo Z, Chen L, Pei D, Jin X, Zhang H. A new nuclear DNA marker from ubiquitin ligase gene region for genetic diversity detection of walnut germplasm resources Biotechnology Reports. 5: 40-45. DOI: 10.1016/j.btre.2014.11.003  0.521
2014 Zahurancik WJ, Klein SJ, Suo Z. Significant contribution of the 3'→5' exonuclease activity to the high fidelity of nucleotide incorporation catalyzed by human DNA polymerase ϵ. Nucleic Acids Research. 42: 13853-60. PMID 25414327 DOI: 10.1093/Nar/Gku1184  0.838
2014 Chu X, Liu F, Maxwell BA, Wang Y, Suo Z, Wang H, Han W, Wang J. Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA. Plos Computational Biology. 10: e1003804. PMID 25188490 DOI: 10.1371/Journal.Pcbi.1003804  0.597
2014 Taggart DJ, Dayeh DM, Fredrickson SW, Suo Z. N-terminal domains of human DNA polymerase lambda promote primer realignment during translesion DNA synthesis. Dna Repair. 22: 41-52. PMID 25108835 DOI: 10.1016/J.Dnarep.2014.07.008  0.486
2014 Gaur V, Vyas R, Fowler JD, Efthimiopoulos G, Feng JY, Suo Z. Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase. Nucleic Acids Research. 42: 9984-95. PMID 25104018 DOI: 10.1093/Nar/Gku709  0.511
2014 Gadkari VV, Tokarsky EJ, Malik CK, Basu AK, Suo Z. Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase. Dna Repair. 21: 65-77. PMID 25048879 DOI: 10.1016/J.Dnarep.2014.06.003  0.849
2014 Vyas R, Zahurancik WJ, Suo Z. Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase λ. Proceedings of the National Academy of Sciences of the United States of America. 111: E3033-42. PMID 25015085 DOI: 10.1073/Pnas.1401286111  0.792
2014 Xu C, Maxwell BA, Suo Z. Conformational dynamics of Thermus aquaticus DNA polymerase I during catalysis. Journal of Molecular Biology. 426: 2901-17. PMID 24931550 DOI: 10.1016/J.Jmb.2014.06.003  0.619
2014 Taggart DJ, Fredrickson SW, Gadkari VV, Suo Z. Mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine bypass catalyzed by human Y-family DNA polymerases. Chemical Research in Toxicology. 27: 931-40. PMID 24779885 DOI: 10.1021/Tx500088E  0.84
2014 Maxwell BA, Suo Z. Recent insight into the kinetic mechanisms and conformational dynamics of Y-Family DNA polymerases. Biochemistry. 53: 2804-14. PMID 24716482 DOI: 10.1021/Bi5000405  0.65
2014 Maxwell BA, Xu C, Suo Z. Conformational dynamics of a Y-family DNA polymerase during substrate binding and catalysis as revealed by interdomain Förster resonance energy transfer. Biochemistry. 53: 1768-78. PMID 24568554 DOI: 10.1021/Bi5000146  0.592
2013 Qin Y, Yang Y, Zhang L, Fowler JD, Qiu W, Wang L, Suo Z, Zhong D. Direct probing of solvent accessibility and mobility at the binding interface of polymerase (Dpo4)-DNA complex. The Journal of Physical Chemistry. A. 117: 13926-34. PMID 24308461 DOI: 10.1021/Jp410051W  0.474
2013 Zahurancik WJ, Klein SJ, Suo Z. Kinetic mechanism of DNA polymerization catalyzed by human DNA polymerase ε. Biochemistry. 52: 7041-9. PMID 24020356 DOI: 10.1021/Bi400803V  0.854
2013 Espinoza-Herrera SJ, Gaur V, Suo Z, Carey PR. Following DNA chain extension and protein conformational changes in crystals of a Y-family DNA polymerase via Raman crystallography. Biochemistry. 52: 4881-90. PMID 23855392 DOI: 10.1021/Bi400524H  0.511
2013 Taggart DJ, Camerlengo TL, Harrison JK, Sherrer SM, Kshetry AK, Taylor JS, Huang K, Suo Z. A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis. Nucleic Acids Research. 41: e96. PMID 23470999 DOI: 10.1093/Nar/Gkt141  0.602
2013 Maxwell BA, Suo Z. Single-molecule investigation of substrate binding kinetics and protein conformational dynamics of a B-family replicative DNA polymerase. The Journal of Biological Chemistry. 288: 11590-600. PMID 23463511 DOI: 10.1074/Jbc.M113.459982  0.624
2012 Göksenin AY, Zahurancik W, LeCompte KG, Taggart DJ, Suo Z, Pursell ZF. Human DNA polymerase ε is able to efficiently extend from multiple consecutive ribonucleotides. The Journal of Biological Chemistry. 287: 42675-84. PMID 23093410 DOI: 10.1074/Jbc.M112.422733  0.819
2012 Sherrer SM, Taggart DJ, Pack LR, Malik CK, Basu AK, Suo Z. Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases. Mutation Research. 737: 25-33. PMID 22917544 DOI: 10.1016/J.Mrfmmm.2012.08.002  0.589
2012 Wang Y, Chu X, Suo Z, Wang E, Wang J. Multidomain protein solves the folding problem by multifunnel combined landscape: theoretical investigation of a Y-family DNA polymerase. Journal of the American Chemical Society. 134: 13755-64. PMID 22827444 DOI: 10.1021/Ja3045663  0.398
2012 Sherrer SM, Maxwell BA, Pack LR, Fiala KA, Fowler JD, Zhang J, Suo Z. Identification of an unfolding intermediate for a DNA lesion bypass polymerase. Chemical Research in Toxicology. 25: 1531-40. PMID 22667759 DOI: 10.1021/Tx3002115  0.794
2012 Gowda AS, Krishnegowda G, Suo Z, Amin S, Spratt TE. Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases. Chemical Research in Toxicology. 25: 1195-202. PMID 22533615 DOI: 10.1021/Tx200483G  0.499
2012 Maxwell BA, Suo Z. Kinetic basis for the differing response to an oxidative lesion by a replicative and a lesion bypass DNA polymerase from Sulfolobus solfataricus. Biochemistry. 51: 3485-96. PMID 22471521 DOI: 10.1021/Bi300246R  0.623
2012 Maxwell BA, Xu C, Suo Z. DNA lesion alters global conformational dynamics of Y-family DNA polymerase during catalysis. The Journal of Biological Chemistry. 287: 13040-7. PMID 22362779 DOI: 10.1074/jbc.M112.345835  0.585
2012 Sherrer SM, Sanman LE, Xia CX, Bolin ER, Malik CK, Efthimiopoulos G, Basu AK, Suo Z. Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases. Chemical Research in Toxicology. 25: 730-40. PMID 22324639 DOI: 10.1021/Tx200531Y  0.619
2012 Song Q, Sherrer SM, Suo Z, Taylor JS. Preparation of site-specific T=mCG cis-syn cyclobutane dimer-containing template and its error-free bypass by yeast and human polymerase η. The Journal of Biological Chemistry. 287: 8021-8. PMID 22262850 DOI: 10.1074/Jbc.M111.333591  0.332
2012 Brown JA, Pack LR, Fowler JD, Suo Z. Presteady state kinetic investigation of the incorporation of anti-hepatitis B nucleotide analogues catalyzed by noncanonical human DNA polymerases. Chemical Research in Toxicology. 25: 225-33. PMID 22132702 DOI: 10.1021/Tx200458S  0.731
2011 Ma D, Fowler JD, Suo Z. Backbone assignment of the little finger domain of a Y-family DNA polymerase. Biomolecular Nmr Assignments. 5: 195-8. PMID 21337030 DOI: 10.1007/S12104-011-9298-1  0.538
2011 Kirouac KN, Suo Z, Ling H. Structural mechanism of ribonucleotide discrimination by a Y-family DNA polymerase. Journal of Molecular Biology. 407: 382-90. PMID 21295588 DOI: 10.1016/J.Jmb.2011.01.037  0.572
2011 Brown JA, Suo Z. Unlocking the sugar "steric gate" of DNA polymerases. Biochemistry. 50: 1135-42. PMID 21226515 DOI: 10.1021/Bi101915Z  0.75
2011 Brown JA, Pack LR, Fowler JD, Suo Z. Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases. Antimicrobial Agents and Chemotherapy. 55: 276-83. PMID 21078938 DOI: 10.1128/Aac.01229-10  0.729
2011 Brown JA, Pack LR, Sanman LE, Suo Z. Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis. Dna Repair. 10: 24-33. PMID 20961817 DOI: 10.1016/J.Dnarep.2010.09.005  0.75
2011 Sherrer SM, Fiala KA, Fowler JD, Newmister SA, Pryor JM, Suo Z. Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases. Nucleic Acids Research. 39: 609-22. PMID 20846959 DOI: 10.1093/Nar/Gkq719  0.793
2010 Sherrer SM, Beyer DC, Xia CX, Fowler JD, Suo Z. Kinetic basis of sugar selection by a Y-family DNA polymerase from Sulfolobus solfataricus P2. Biochemistry. 49: 10179-86. PMID 20973506 DOI: 10.1021/Bi101465N  0.652
2010 Brown JA, Pack LR, Sherrer SM, Kshetry AK, Newmister SA, Fowler JD, Taylor JS, Suo Z. Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ. Journal of Molecular Biology. 403: 505-15. PMID 20851705 DOI: 10.1016/J.Jmb.2010.09.014  0.727
2010 Brown JA, Zhang L, Sherrer SM, Taylor JS, Burgers PM, Suo Z. Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Journal of Nucleic Acids. 2010. PMID 20798853 DOI: 10.4061/2010/871939  0.748
2010 Ma D, Fowler JD, Yuan C, Suo Z. Backbone assignment of the catalytic core of a Y-family DNA polymerase. Biomolecular Nmr Assignments. 4: 207-9. PMID 20582735 DOI: 10.1007/S12104-010-9244-7  0.62
2010 Brown JA, Fowler JD, Suo Z. Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase. Biochemistry. 49: 5504-10. PMID 20518555 DOI: 10.1021/Bi100433X  0.717
2010 Wong JH, Brown JA, Suo Z, Blum P, Nohmi T, Ling H. Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. The Embo Journal. 29: 2059-69. PMID 20512114 DOI: 10.1038/Emboj.2010.101  0.703
2010 Brown JA, Fiala KA, Fowler JD, Sherrer SM, Newmister SA, Duym WW, Suo Z. A novel mechanism of sugar selection utilized by a human X-family DNA polymerase. Journal of Molecular Biology. 395: 282-90. PMID 19900463 DOI: 10.1016/J.Jmb.2009.11.003  0.846
2009 Xu C, Maxwell BA, Brown JA, Zhang L, Suo Z. Global conformational dynamics of a Y-family DNA polymerase during catalysis. Plos Biology. 7: e1000225. PMID 19859523 DOI: 10.1371/Journal.Pbio.1000225  0.753
2009 Fowler JD, Brown JA, Kvaratskhelia M, Suo Z. Probing conformational changes of human DNA polymerase lambda using mass spectrometry-based protein footprinting. Journal of Molecular Biology. 390: 368-79. PMID 19467241 DOI: 10.1016/J.Jmb.2009.05.037  0.731
2009 Brown JA, Suo Z. Elucidating the kinetic mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase B1. Biochemistry. 48: 7502-11. PMID 19456143 DOI: 10.1021/Bi9005336  0.729
2009 Zhang L, Brown JA, Newmister SA, Suo Z. Polymerization fidelity of a replicative DNA polymerase from the hyperthermophilic archaeon Sulfolobus solfataricus P2. Biochemistry. 48: 7492-501. PMID 19456141 DOI: 10.1021/Bi900532W  0.685
2009 Sherrer SM, Brown JA, Pack LR, Jasti VP, Fowler JD, Basu AK, Suo Z. Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase. The Journal of Biological Chemistry. 284: 6379-88. PMID 19124465 DOI: 10.1074/Jbc.M808161200  0.731
2008 DeCarlo L, Gowda AS, Suo Z, Spratt TE. Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV. Biochemistry. 47: 8157-64. PMID 18616289 DOI: 10.1021/Bi800820M  0.542
2008 Brown JA, Newmister SA, Fiala KA, Suo Z. Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase. Nucleic Acids Research. 36: 3867-78. PMID 18499711 DOI: 10.1093/Nar/Gkn309  0.857
2008 Wong JH, Fiala KA, Suo Z, Ling H. Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4. Journal of Molecular Biology. 379: 317-30. PMID 18448122 DOI: 10.1016/J.Jmb.2008.03.038  0.832
2008 Fowler JD, Brown JA, Johnson KA, Suo Z. Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase. The Journal of Biological Chemistry. 283: 15339-48. PMID 18378680 DOI: 10.1074/Jbc.M800310200  0.777
2008 Fiala KA, Sherrer SM, Brown JA, Suo Z. Mechanistic consequences of temperature on DNA polymerization catalyzed by a Y-family DNA polymerase. Nucleic Acids Research. 36: 1990-2001. PMID 18276639 DOI: 10.1093/Nar/Gkn004  0.798
2007 Brown JA, Duym WW, Fowler JD, Suo Z. Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta. Journal of Molecular Biology. 367: 1258-69. PMID 17321545 DOI: 10.1016/J.Jmb.2007.01.069  0.74
2007 Fiala KA, Suo Z. Sloppy bypass of an abasic lesion catalyzed by a Y-family DNA polymerase. The Journal of Biological Chemistry. 282: 8199-206. PMID 17234630 DOI: 10.1074/Jbc.M610719200  0.791
2007 Fiala KA, Hypes CD, Suo Z. Mechanism of abasic lesion bypass catalyzed by a Y-family DNA polymerase. The Journal of Biological Chemistry. 282: 8188-98. PMID 17210571 DOI: 10.1074/Jbc.M610718200  0.821
2007 Fiala KA, Brown JA, Ling H, Kshetry AK, Zhang J, Taylor JS, Yang W, Suo Z. Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. Journal of Molecular Biology. 365: 590-602. PMID 17095011 DOI: 10.1016/J.Jmb.2006.10.008  0.855
2006 Duym WW, Fiala KA, Bhatt N, Suo Z. Kinetic effect of a downstream strand and its 5'-terminal moieties on single nucleotide gap-filling synthesis catalyzed by human DNA polymerase lambda. The Journal of Biological Chemistry. 281: 35649-55. PMID 17005572 DOI: 10.1074/Jbc.M607479200  0.841
2006 Fiala KA, Duym WW, Zhang J, Suo Z. Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain. The Journal of Biological Chemistry. 281: 19038-44. PMID 16675458 DOI: 10.1074/Jbc.M601178200  0.831
2005 Suo Z. Thioesterase portability and peptidyl carrier protein swapping in yersiniabactin synthetase from Yersinia pestis. Biochemistry. 44: 4926-38. PMID 15779920 DOI: 10.1021/Bi047538S  0.32
2004 Roettger MP, Fiala KA, Sompalli S, Dong Y, Suo Z. Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu. Biochemistry. 43: 13827-38. PMID 15504045 DOI: 10.1021/Bi048782M  0.811
2004 Fiala KA, Abdel-Gawad W, Suo Z. Pre-steady-state kinetic studies of the fidelity and mechanism of polymerization catalyzed by truncated human DNA polymerase lambda. Biochemistry. 43: 6751-62. PMID 15157109 DOI: 10.1021/Bi049975C  0.844
2004 Fiala KA, Suo Z. Mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase IV. Biochemistry. 43: 2116-25. PMID 14967051 DOI: 10.1021/Bi035746Z  0.84
2004 Fiala KA, Suo Z. Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. Biochemistry. 43: 2106-15. PMID 14967050 DOI: 10.1021/Bi0357457  0.843
2001 Johnson AA, Ray AS, Hanes J, Suo Z, Colacino JM, Anderson KS, Johnson KA. Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase. The Journal of Biological Chemistry. 276: 40847-57. PMID 11526116 DOI: 10.1074/Jbc.M106743200  0.786
2001 Suo Z, Tseng CC, Walsh CT. Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase. Proceedings of the National Academy of Sciences of the United States of America. 98: 99-104. PMID 11134531 DOI: 10.1073/Pnas.98.1.99  0.626
2000 Suo Z, Chen H, Walsh CT. Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing. Proceedings of the National Academy of Sciences of the United States of America. 97: 14188-93. PMID 11106385 DOI: 10.1073/Pnas.260495697  0.486
2000 Keating TA, Suo Z, Ehmann DE, Walsh CT. Selectivity of the yersiniabactin synthetase adenylation domain in the two-step process of amino acid activation and transfer to a holo-carrier protein domain. Biochemistry. 39: 2297-306. PMID 10694396 DOI: 10.1021/Bi992341Z  0.714
1999 Suo Z, Walsh CT, Miller DA. Tandem heterocyclization activity of the multidomain 230 kDa HMWP2 subunit of yersinia pestis yersiniabactin synthetase: interaction of the 1-1382 and 1383-2035 fragments Biochemistry. 38: 17000. PMID 10606536  0.561
1999 Suo Z, Walsh CT, Miller DA. Tandem heterocyclization activity of the multidomain 230 kDa HMWP2 subunit of Yersinia pestis yersiniabactin synthetase: interaction of the 1-1382 and 1383-2035 fragments. Biochemistry. 38: 14023-35. PMID 10529249 DOI: 10.1021/Bi991574N  0.627
1999 Suo Z, Lippard SJ, Johnson KA. Single d(GpG)/cis-diammineplatinum(II) adduct-induced inhibition of DNA polymerization. Biochemistry. 38: 715-26. PMID 9888812 DOI: 10.1021/Bi981854N  0.723
1998 Suo Z, Johnson KA. DNA secondary structure effects on DNA synthesis catalyzed by HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 273: 27259-67. PMID 9765249 DOI: 10.1074/Jbc.273.42.27259  0.652
1998 Suo Z, Johnson KA. Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor, (R)-9-(2-Phosphonylmethoxypropyl)adenine. The Journal of Biological Chemistry. 273: 27250-8. PMID 9765248 DOI: 10.1074/Jbc.273.42.27250  0.695
1997 Suo Z, Johnson KA. RNA secondary structure switching during DNA synthesis catalyzed by HIV-1 reverse transcriptase. Biochemistry. 36: 14778-85. PMID 9398198 DOI: 10.1021/Bi971963M  0.533
1997 Suo Z, Johnson KA. Effect of RNA secondary structure on RNA cleavage catalyzed by HIV-1 reverse transcriptase. Biochemistry. 36: 12468-76. PMID 9376351 DOI: 10.1021/Bi971218+  0.554
1997 Suo Z, Johnson KA. Effect of RNA secondary structure on the kinetics of DNA synthesis catalyzed by HIV-1 reverse transcriptase. Biochemistry. 36: 12459-67. PMID 9376350 DOI: 10.1021/Bi971217H  0.62
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