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Ali Al-Hakim - Publications

Affiliations: 
1988-1990 University of Iowa, Iowa City, IA 
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Szajek AY, Chess E, Johansen K, Gratzl G, Gray E, Keire D, Linhardt RJ, Liu J, Morris T, Mulloy B, Nasr M, Shriver Z, Torralba P, Viskov C, Williams R, ... ... Al-Hakim A, et al. The US regulatory and pharmacopeia response to the global heparin contamination crisis. Nature Biotechnology. 34: 625-630. PMID 27281424 DOI: 10.1038/Nbt.3606  0.481
2013 Ye H, Toby TK, Sommers CD, Ghasriani H, Trehy ML, Ye W, Kolinski RE, Buhse LF, Al-Hakim A, Keire DA. Characterization of currently marketed heparin products: key tests for LMWH quality assurance. Journal of Pharmaceutical and Biomedical Analysis. 85: 99-107. PMID 23917037 DOI: 10.1016/J.Jpba.2013.06.033  0.368
2013 Keire DA, Buhse LF, al-Hakim A. Characterization of currently marketed heparin products: composition analysis by 2D-NMR Analytical Methods. 5: 2984-2994. DOI: 10.1039/C3Ay40226F  0.35
2012 Wang B, Buhse LF, Al-Hakim A, Boyne Ii MT, Keire DA. Characterization of currently marketed heparin products: analysis of heparin digests by RPIP-UHPLC-QTOF-MS. Journal of Pharmaceutical and Biomedical Analysis. 67: 42-50. PMID 22633605 DOI: 10.1016/J.Jpba.2012.04.033  0.363
2011 Sommers CD, Ye H, Kolinski RE, Nasr M, Buhse LF, Al-Hakim A, Keire DA. Characterization of currently marketed heparin products: analysis of molecular weight and heparinase-I digest patterns. Analytical and Bioanalytical Chemistry. 401: 2445-54. PMID 21901459 DOI: 10.1007/S00216-011-5362-Z  0.329
2011 Zang Q, Keire DA, Buhse LF, Wood RD, Mital DP, Haque S, Srinivasan S, Moore CM, Nasr M, Al-Hakim A, Trehy ML, Welsh WJ. Identification of heparin samples that contain impurities or contaminants by chemometric pattern recognition analysis of proton NMR spectral data. Analytical and Bioanalytical Chemistry. 401: 939-55. PMID 21678118 DOI: 10.1007/S00216-011-5155-4  0.337
2011 Zang Q, Keire DA, Wood RD, Buhse LF, Moore CM, Nasr M, Al-Hakim A, Trehy ML, Welsh WJ. Combining (1)H NMR spectroscopy and chemometrics to identify heparin samples that may possess dermatan sulfate (DS) impurities or oversulfated chondroitin sulfate (OSCS) contaminants. Journal of Pharmaceutical and Biomedical Analysis. 54: 1020-9. PMID 21215547 DOI: 10.1016/J.Jpba.2010.12.008  0.378
2011 Zang Q, Keire DA, Wood RD, Buhse LF, Moore CM, Nasr M, Al-Hakim A, Trehy ML, Welsh WJ. Class modeling analysis of heparin 1H NMR spectral data using the soft independent modeling of class analogy and unequal class modeling techniques. Analytical Chemistry. 83: 1030-9. PMID 21192734 DOI: 10.1021/Ac102832T  0.302
2011 Zang Q, Keire DA, Wood RD, Buhse LF, Moore CM, Nasr M, Al-Hakim A, Trehy ML, Welsh WJ. Determination of galactosamine impurities in heparin samples by multivariate regression analysis of their (1)H NMR spectra. Analytical and Bioanalytical Chemistry. 399: 635-49. PMID 20953772 DOI: 10.1007/S00216-010-4268-5  0.358
2011 Keire DA, Ye H, Trehy ML, Ye W, Kolinski RE, Westenberger BJ, Buhse LF, Nasr M, Al-Hakim A. Characterization of currently marketed heparin products: key tests for quality assurance. Analytical and Bioanalytical Chemistry. 399: 581-91. PMID 20680615 DOI: 10.1007/S00216-010-4023-Y  0.346
2010 Brustkern AM, Buhse LF, Nasr M, Al-Hakim A, Keire DA. Characterization of currently marketed heparin products: reversed-phase ion-pairing liquid chromatography mass spectrometry of heparin digests. Analytical Chemistry. 82: 9865-70. PMID 21069966 DOI: 10.1021/Ac102301J  0.307
2008 Guerrini M, Beccati D, Shriver Z, Naggi A, Viswanathan K, Bisio A, Capila I, Lansing JC, Guglieri S, Fraser B, Al-Hakim A, Gunay NS, Zhang Z, Robinson L, Buhse L, et al. Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events. Nature Biotechnology. 26: 669-75. PMID 18437154 DOI: 10.1038/Nbt1407  0.584
2008 Kishimoto TK, Viswanathan K, Ganguly T, Elankumaran S, Smith S, Pelzer K, Lansing JC, Sriranganathan N, Zhao G, Galcheva-Gargova Z, Al-Hakim A, Bailey GS, Fraser B, Roy S, Rogers-Cotrone T, et al. Contaminated heparin associated with adverse clinical events and activation of the contact system. The New England Journal of Medicine. 358: 2457-67. PMID 18434646 DOI: 10.1056/Nejmoa0803200  0.447
1994 Pervin A, al-Hakim A, Linhardt RJ. Separation of glycosaminoglycan-derived oligosaccharides by capillary electrophoresis using reverse polarity. Analytical Biochemistry. 221: 182-8. PMID 7985791 DOI: 10.1006/Abio.1994.1395  0.668
1992 Edens RE, al-Hakim A, Weiler JM, Rethwisch DG, Fareed J, Linhardt RJ. Gradient polyacrylamide gel electrophoresis for determination of molecular weights of heparin preparations and low-molecular-weight heparin derivatives. Journal of Pharmaceutical Sciences. 81: 823-7. PMID 1328601 DOI: 10.1002/Jps.2600810821  0.676
1991 Lee KB, al-Hakim A, Loganathan D, Linhardt RJ. A new method for sequencing linear oligosaccharides on gels using charged, fluorescent conjugates. Carbohydrate Research. 214: 155-68. PMID 1954629 DOI: 10.1016/S0008-6215(00)90538-X  0.629
1991 Linhardt RJ, al-Hakim A, Liu JA, Hoppensteadt D, Mascellani G, Bianchini P, Fareed J. Structural features of dermatan sulfates and their relationship to anticoagulant and antithrombotic activities. Biochemical Pharmacology. 42: 1609-19. PMID 1930287 DOI: 10.1016/0006-2952(91)90431-4  0.529
1991 al-Hakim A, Linhardt RJ. Capillary electrophoresis for the analysis of chondroitin sulfate- and dermatan sulfate-derived disaccharides. Analytical Biochemistry. 195: 68-73. PMID 1909508 DOI: 10.1016/0003-2697(91)90296-6  0.516
1990 Linhardt RJ, Loganathan D, al-Hakim A, Wang HM, Walenga JM, Hoppensteadt D, Fareed J. Oligosaccharide mapping of low molecular weight heparins: structure and activity differences. Journal of Medicinal Chemistry. 33: 1639-45. PMID 2160537 DOI: 10.1021/Jm00168A017  0.652
1990 al-Hakim A, Linhardt RJ. Isolation and recovery of acidic oligosaccharides from polyacrylamide gels by semi-dry electrotransfer. Electrophoresis. 11: 23-8. PMID 1690641 DOI: 10.1002/Elps.1150110106  0.407
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