| Year |
Citation |
Score |
| 2008 |
Chowdhury UK, Aposhian HV. Protein expression in the livers and urinary bladders of hamsters exposed to sodium arsenite. Annals of the New York Academy of Sciences. 1140: 325-34. PMID 18991932 DOI: 10.1196/Annals.1454.019 |
0.337 |
|
| 2006 |
Chowdhury UK, Zakharyan RA, Hernandez A, Avram MD, Kopplin MJ, Aposhian HV. Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration. Toxicology and Applied Pharmacology. 216: 446-57. PMID 16930657 DOI: 10.1016/J.Taap.2006.06.014 |
0.385 |
|
| 2006 |
Aposhian HV, Aposhian MM. Arsenic toxicology: five questions. Chemical Research in Toxicology. 19: 1-15. PMID 16411650 DOI: 10.1021/Tx050106D |
0.312 |
|
| 2005 |
Zakharyan RA, Tsaprailis G, Chowdhury UK, Hernandez A, Aposhian HV. Interactions of sodium selenite, glutathione, arsenic species, and omega class human glutathione transferase. Chemical Research in Toxicology. 18: 1287-95. PMID 16097802 DOI: 10.1021/Tx0500530 |
0.377 |
|
| 2004 |
Aposhian HV, Zakharyan RA, Avram MD, Sampayo-Reyes A, Wollenberg ML. A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species. Toxicology and Applied Pharmacology. 198: 327-35. PMID 15276412 DOI: 10.1016/J.Taap.2003.10.027 |
0.463 |
|
| 2003 |
Marnell LL, Garcia-Vargas GG, Chowdhury UK, Zakharyan RA, Walsh B, Avram MD, Kopplin MJ, Cebrián ME, Silbergeld EK, Aposhian HV. Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles. Chemical Research in Toxicology. 16: 1507-13. PMID 14680363 DOI: 10.1021/Tx034149A |
0.392 |
|
| 2003 |
Carter DE, Aposhian HV, Gandolfi AJ. The metabolism of inorganic arsenic oxides, gallium arsenide, and arsine: a toxicochemical review. Toxicology and Applied Pharmacology. 193: 309-34. PMID 14678742 DOI: 10.1016/J.Taap.2003.07.009 |
0.326 |
|
| 2003 |
Aposhian HV, Zakharyan RA, Avram MD, Kopplin MJ, Wollenberg ML. Oxidation and detoxification of trivalent arsenic species. Toxicology and Applied Pharmacology. 193: 1-8. PMID 14613711 DOI: 10.1016/S0041-008X(03)00324-7 |
0.333 |
|
| 2003 |
Loffredo CA, Aposhian HV, Cebrian ME, Yamauchi H, Silbergeld EK. Variability in human metabolism of arsenic. Environmental Research. 92: 85-91. PMID 12854687 DOI: 10.1016/S0013-9351(02)00081-6 |
0.405 |
|
| 2002 |
Gong Z, Jiang G, Cullen WR, Aposhian HV, Le XC. Determination of arsenic metabolic complex excreted in human urine after administration of sodium 2,3-dimercapto-1-propane sulfonate. Chemical Research in Toxicology. 15: 1318-23. PMID 12387631 DOI: 10.1021/Tx020058M |
0.41 |
|
| 2002 |
Radabaugh TR, Sampayo-Reyes A, Zakharyan RA, Aposhian HV. Arsenate reductase II. Purine nucleoside phosphorylase in the presence of dihydrolipoic acid is a route for reduction of arsenate to arsenite in mammalian systems. Chemical Research in Toxicology. 15: 692-8. PMID 12018991 DOI: 10.1021/Tx0101853 |
0.396 |
|
| 2001 |
Wildfang E, Radabaugh TR, Aposhian HV. Enzymatic methylation of arsenic compounds. IX. Liver arsenite methyltransferase and arsenate reductase activities in primates. Toxicology. 168: 213-221. PMID 11684318 DOI: 10.1016/S0300-483X(01)00481-4 |
0.763 |
|
| 2001 |
Zakharyan RA, Sampayo-Reyes A, Healy SM, Tsaprailis G, Board PG, Liebler DC, Aposhian HV. Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily. Chemical Research in Toxicology. 14: 1051-7. PMID 11511179 DOI: 10.1021/Tx010052H |
0.735 |
|
| 2001 |
Petrick JS, Jagadish B, Mash EA, Aposhian HV. Monomethylarsonous acid (MMA(III)) and arsenite: LD(50) in hamsters and in vitro inhibition of pyruvate dehydrogenase. Chemical Research in Toxicology. 14: 651-6. PMID 11409934 |
0.335 |
|
| 2000 |
Le XC, Ma M, Cullen WR, Aposhian HV, Lu X, Zheng B. Determination of monomethylarsonous acid, a key arsenic methylation intermediate, in human urine. Environmental Health Perspectives. 108: 1015-8. PMID 11102289 DOI: 10.1289/Ehp.001081015 |
0.334 |
|
| 2000 |
Sampayo-Reyes A, Zakharyan RA, Healy SM, Aposhian HV. Monomethylarsonic acid reductase and monomethylarsonous acid in hamster tissue. Chemical Research in Toxicology. 13: 1181-6. PMID 11087441 DOI: 10.1021/Tx000154S |
0.767 |
|
| 2000 |
Le XC, Lu X, Ma M, Cullen WR, Aposhian HV, Zheng B. Speciation of key arsenic metabolic intermediates in human urine. Analytical Chemistry. 72: 5172-7. PMID 11080860 DOI: 10.1021/Ac000527U |
0.31 |
|
| 2000 |
Aposhian HV, Gurzau ES, Le XC, Gurzau A, Healy SM, Lu X, Ma M, Yip L, Zakharyan RA, Maiorino RM, Dart RC, Tircus MG, Gonzalez-Ramirez D, Morgan DL, Avram D, et al. Occurrence of monomethylarsonous acid in urine of humans exposed to inorganic arsenic. Chemical Research in Toxicology. 13: 693-7. PMID 10956055 DOI: 10.1021/Tx000114O |
0.751 |
|
| 2000 |
Aposhian HV, Zheng B, Aposhian MM, Le XC, Cebrian ME, Cullen W, Zakharyan RA, Ma M, Dart RC, Cheng Z, Andrewes P, Yip L, O'Malley GF, Maiorino RM, Van Voorhies W, et al. DMPS-arsenic challenge test. II. Modulation of arsenic species, including monomethylarsonous acid (MMA(III)), excreted in human urine. Toxicology and Applied Pharmacology. 165: 74-83. PMID 10814555 DOI: 10.1006/Taap.2000.8922 |
0.753 |
|
| 2000 |
Radabaugh TR, Aposhian HV. Enzymatic reduction of arsenic compounds in mammalian systems: reduction of arsenate to arsenite by human liver arsenate reductase. Chemical Research in Toxicology. 13: 26-30. PMID 10649963 DOI: 10.1021/tx990115k |
0.343 |
|
| 2000 |
Gailer J, George GN, Pickering IJ, Prince RC, Ringwald SC, Pemberton JE, Glass RS, Younis HS, DeYoung DW, Aposhian HV. A metabolic link between arsenite and selenite: The seleno-bis(S- glutathionyl) arsinium ion Journal of the American Chemical Society. 122: 4637-4639. DOI: 10.1021/Ja993064M |
0.323 |
|
| 1999 |
Zakharyan RA, Aposhian HV. Enzymatic reduction of arsenic compounds in mammalian systems: the rate-limiting enzyme of rabbit liver arsenic biotransformation is MMA(V) reductase. Chemical Research in Toxicology. 12: 1278-83. PMID 10604879 DOI: 10.1021/Tx9901231 |
0.378 |
|
| 1999 |
Zakharyan RA, Ayala-Fierro F, Cullen WR, Carter DM, Aposhian HV. Enzymatic methylation of arsenic compounds. VII. Monomethylarsonous acid (MMAIII) is the substrate for MMA methyltransferase of rabbit liver and human hepatocytes. Toxicology and Applied Pharmacology. 158: 9-15. PMID 10387927 DOI: 10.1006/taap.1999.8687 |
0.385 |
|
| 1999 |
Healy SM, Wildfang E, Zakharyan RA, Aposhian HV. Diversity of inorganic arsenite biotransformation. Biological Trace Element Research. 68: 249-66. PMID 10328340 DOI: 10.1007/BF02783907 |
0.721 |
|
| 1999 |
Zakharyan RA, Aposhian HV. Arsenite methylation by methylvitamin B12 and glutathione does not require an enzyme. Toxicology and Applied Pharmacology. 154: 287-91. PMID 9931288 DOI: 10.1006/Taap.1998.8587 |
0.478 |
|
| 1998 |
Wildfang E, Zakharyan RA, Aposhian HV. Enzymatic methylation of arsenic compounds. VI. Characterization of hamster liver arsenite and methylarsonic acid methyltransferase activities in vitro. Toxicology and Applied Pharmacology. 152: 366-75. PMID 9853005 DOI: 10.1006/Taap.1998.8409 |
0.766 |
|
| 1998 |
Healy SM, Casarez EA, Ayala-Fierro F, Aposhian H. Enzymatic methylation of arsenic compounds. V. Arsenite methyltransferase activity in tissues of mice. Toxicology and Applied Pharmacology. 148: 65-70. PMID 9465265 DOI: 10.1006/Taap.1997.8306 |
0.746 |
|
| 1997 |
Healy SM, Zakharyan RA, Aposhian HV. Enzymatic methylation of arsenic compounds: IV. In vitro and in vivo deficiency of the methylation of arsenite and monomethylarsonic acid in the guinea pig. Mutation Research. 386: 229-39. PMID 9219561 DOI: 10.1016/S1383-5742(97)00014-8 |
0.745 |
|
| 1997 |
Aposhian HV. Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity. Annual Review of Pharmacology and Toxicology. 37: 397-419. PMID 9131259 DOI: 10.1146/Annurev.Pharmtox.37.1.397 |
0.464 |
|
| 1997 |
Keith RL, Setiarahardjo I, Fernando Q, Aposhian HV, Gandolfi AJ. Utilization of renal slices to evaluate the efficacy of chelating agents for removing mercury from the kidney. Toxicology. 116: 67-75. PMID 9020508 DOI: 10.1016/S0300-483X(96)03531-7 |
0.48 |
|
| 1996 |
Zakharyan RA, Wildfang E, Aposhian HV. Enzymatic Methylation of Arsenic Compounds Toxicology and Applied Pharmacology. 140: 77-84. PMID 8813004 |
0.418 |
|
| 1996 |
Zakharyan RA, Wildfang E, Aposhian HV. Enzymatic methylation of arsenic compounds. III. The marmoset and tamarin, but not the rhesus, monkeys are deficient in methyltransferases that methylate inorganic arsenic. Toxicology and Applied Pharmacology. 140: 77-84. PMID 8806872 DOI: 10.1006/Taap.1996.0199 |
0.774 |
|
| 1995 |
Zakharyan R, Wu Y, Bogdan GM, Aposhian HV. Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver. Chemical Research in Toxicology. 8: 1029-38. PMID 8605285 |
0.345 |
|
| 1995 |
Aposhian HV, Maiorino RM, Gonzalez-Ramirez D, Zuniga-Charles M, Xu Z, Hurlbut KM, Junco-Munoz P, Dart RC, Aposhian MM. Mobilization of heavy metals by newer, therapeutically useful chelating agents. Toxicology. 97: 23-38. PMID 7716789 DOI: 10.1016/0300-483X(95)02965-B |
0.392 |
|
| 1995 |
Ingersoll RT, Montgomery EB, Aposhian HV. Central nervous system toxicity of manganese. I. Inhibition of spontaneous motor activity in rats after intrathecal administration of manganese chloride. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 27: 106-13. PMID 7589920 DOI: 10.1006/Faat.1995.1113 |
0.308 |
|
| 1994 |
Bogdan GM, Sampayo-Reyes A, Aposhian HV. Arsenic binding proteins of mammalian systems: I. Isolation of three arsenite-binding proteins of rabbit liver. Toxicology. 93: 175-93. PMID 7974513 DOI: 10.1016/0300-483X(94)90077-9 |
0.329 |
|
| 1993 |
Aposhian HV, Levine DJ, Rivera M, Fernando Q. Determination and metabolism of dithiol chelating agents: the zinc chelate of the dimethyl ester of meso-2,3-dimercaptosuccinic acid increase biliary excretion of cadmium and platinum. Chemical Research in Toxicology. 6: 208-14. PMID 8386560 |
0.541 |
|
| 1992 |
Aposhian HV, Maiorino RM, Rivera M, Bruce DC, Dart RC, Hurlbut KM, Levine DJ, Zheng W, Fernando Q, Carter D. Human studies with the chelating agents, DMPS and DMSA. Journal of Toxicology. Clinical Toxicology. 30: 505-28. PMID 1331491 DOI: 10.3109/15563659209017938 |
0.696 |
|
| 1991 |
Rivera M, Bruck MA, Aposhian HV, Fernando Q. The dimethyl ester of meso-2,3-dimercaptosuccinic acid and its interactions with Cd2+ and rabbit liver metallothionein I. Chemical Research in Toxicology. 4: 572-80. PMID 1665353 |
0.498 |
|
| 1991 |
Rivera M, Levine DJ, Aposhian HV, Fernando Q. Synthesis and properties of the monomethyl ester of meso-dimercaptosuccinic acid and its chelates of lead (II), cadmium(II), and mercury(II). Chemical Research in Toxicology. 4: 107-14. PMID 1655086 DOI: 10.1021/Tx00019A015 |
0.678 |
|
| 1990 |
Zheng W, Maiorino RM, Brendel K, Aposhian HV. Determination and metabolism of dithiol chelating agents. VII. Biliary excretion of dithiols and their interactions with cadmium and metallothionein. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 14: 598-607. PMID 2160390 DOI: 10.1016/0272-0590(90)90264-K |
0.352 |
|
| 1989 |
Rivera M, Aposhian HV, Fernando Q. Lead chelates of meso- and racemic-dimercaptosuccinic acid. Journal of Inorganic Biochemistry. 37: 283-93. PMID 2560792 DOI: 10.1016/0162-0134(89)85003-2 |
0.496 |
|
| 1989 |
Rivera M, Zheng W, Aposhian HV, Fernando Q. Determination and metabolism of dithiol chelating agents. VIII. Metal complexes of meso-dimercaptosuccinic acid. Toxicology and Applied Pharmacology. 100: 96-106. PMID 2548305 DOI: 10.1016/0041-008X(89)90094-X |
0.64 |
|
| 1989 |
Aposhian HV, Maiorino RM, Dart RC, Perry DF. Urinary excretion of meso-2,3-dimercaptosuccinic acid in human subjects. Clinical Pharmacology and Therapeutics. 45: 520-6. PMID 2541962 DOI: 10.1038/Clpt.1989.67 |
0.369 |
|
| 1989 |
Maiorino RM, Aposhian HV. Determination and metabolism of dithiol chelating agents. IV. Urinary excretion of meso-2,3-dimercaptosuccinic acid and mercaptosuccinic acid in rabbits given meso-2,3-dimercaptosuccinic acid. Biochemical Pharmacology. 38: 1147-54. PMID 2539817 DOI: 10.1016/0006-2952(89)90261-X |
0.388 |
|
| 1989 |
Maiorino RM, Bruce DC, Aposhian HV. Determination and metabolism of dithiol chelating agents. VI. Isolation and identification of the mixed disulfides of meso-2,3-dimercaptosuccinic acid with L-cysteine in human urine. Toxicology and Applied Pharmacology. 97: 338-49. PMID 2538007 DOI: 10.1016/0041-008X(89)90338-4 |
0.349 |
|
| 1989 |
Aposhian HV, Aposhian MM. Newer Developments in Arsenic Toxicity Journal of the American College of Toxicology. 8: 1297-1305. DOI: 10.3109/10915818909009121 |
0.363 |
|
| 1987 |
Maiorino RM, Barry TJ, Aposhian HV. Determination and metabolism of dithiol-chelating agents: electrolytic and chemical reduction of oxidized dithiols in urine. Analytical Biochemistry. 160: 217-26. PMID 3032019 DOI: 10.1016/0003-2697(87)90633-6 |
0.34 |
|
| 1986 |
Maiorino RM, Weber GL, Aposhian HV. Fluorometric determination of 2,3-dimercaptopropane-1-sulfonic acid and other dithiols by precolumn derivatization with bromobimane and column liquid chromatography. Journal of Chromatography. 374: 297-310. PMID 3958088 DOI: 10.1016/S0378-4347(00)83285-5 |
0.307 |
|
| 1985 |
Maiorino RM, Aposhian HV. Dimercaptan metal-binding agents influence the biotransformation of arsenite in the rabbit. Toxicology and Applied Pharmacology. 77: 240-50. PMID 2983455 DOI: 10.1016/0041-008X(85)90323-0 |
0.436 |
|
| 1984 |
Stine ER, Hsu CA, Hoover TD, Aposhian HV, Carter DE. N-(2,3-dimercaptopropyl)phthalamidic acid: protection, in vivo and in vitro, against arsenic intoxication. Toxicology and Applied Pharmacology. 75: 329-36. PMID 6474464 DOI: 10.1016/0041-008X(84)90215-1 |
0.364 |
|
| 1984 |
Aposhian HV, Carter DE, Hoover TD, Hsu CA, Maiorino RM, Stine E. DMSA, DMPS, and DMPA--as arsenic antidotes. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: S58-70. PMID 6327446 DOI: 10.1016/0272-0590(84)90138-6 |
0.382 |
|
| 1983 |
Aposhian HV, Hsu CA, Hoover TD. DL- and meso-dimercaptosuccinic acid: in vitro and in vivo studies with sodium arsenite. Toxicology and Applied Pharmacology. 69: 206-13. PMID 6306868 DOI: 10.1016/0041-008X(83)90301-0 |
0.417 |
|
| 1982 |
Aposhian HV. Biological chelation: 2,3-dimercapto-propanesulfonic acid and meso-dimercaptosuccinic acid. Advances in Enzyme Regulation. 20: 301-19. PMID 6287818 DOI: 10.1016/0065-2571(82)90022-X |
0.385 |
|
| 1980 |
Tadlock CH, Aposhian HV. Protection of mice against the lethal effects of sodium arsenite by 2,3 dimercapto-1-propane-sulfonic acid and dimercaptosuccinic acid. Biochemical and Biophysical Research Communications. 94: 501-7. PMID 6249288 DOI: 10.1016/0006-291X(80)91259-0 |
0.369 |
|
| 1964 |
RICHARDSON CC, SCHILDKRAUT CL, APOSHIAN HV, KORNBERG A. ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI. The Journal of Biological Chemistry. 239: 222-32. PMID 14114848 |
0.562 |
|
| 1962 |
APOSHIAN HV, KORNBERG A. Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: a new enzyme The Journal of Biological Chemistry. 237: 519-525. PMID 13861902 |
0.436 |
|
| 1960 |
LAMBOOY JP, APOSHIAN HV. The biological activity of 6-ethyl-9-(1'-D-ribityl)-isoalloxazine The Journal of Nutrition. 71: 182-187. PMID 14413632 |
0.589 |
|
| 1955 |
Aposhian HV, Lambooy JP. The in vivo Synthesis of Diethylriboflavin Phosphate1,2 Journal of the American Chemical Society. 77: 6368-6368. DOI: 10.1021/Ja01628A086 |
0.604 |
|
| 1952 |
LAMBOOY JP, APOSHIAN HV. The biological activity of diethyl riboflavin The Journal of Nutrition. 47: 539-559. PMID 14955709 |
0.61 |
|
| 1951 |
Aposhian HV, Lambooy JP. Retardation of Growth of Walker Rat Carcinoma 256 by Administration of Diethyl Riboflavin Proceedings of the Society For Experimental Biology and Medicine. 78: 197-199. PMID 14891965 DOI: 10.3181/00379727-78-19019 |
0.571 |
|
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