Peter John Myler, PhD - Publications

Affiliations: 
2020- Pediatrics University of Washington, Seattle, Seattle, WA 
Area:
Molecular parasitology, genomics, bioinformatics
Website:
https://www.seattlechildrens.org/directory/peter-j-myler/

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Year Citation  Score
2021 Jensen BC, Phan IQ, McDonald JR, Sur A, Gillespie MA, Ranish JA, Parsons M, Myler PJ. Chromatin-Associated Protein Complexes Link DNA Base J and Transcription Termination in . Msphere. 6. PMID 33627513 DOI: 10.1128/mSphere.01204-20  0.322
2020 Goldman-Pinkovich A, Kannan S, Nitzan-Koren R, Puri M, Pawar H, Bar-Avraham Y, McDonald J, Sur A, Zhang WW, Matlashewski G, Madhubala R, Michaeli S, Myler PJ, Zilberstein D. Sensing Host Arginine Is Essential for Parasites' Intracellular Development. Mbio. 11. PMID 33051367 DOI: 10.1128/mBio.02023-20  0.59
2019 Ruy PC, Monteiro Teles NM, Miserani Magalhães RD, Freitas de Castro F, Dias L, Aquino Defina TP, Rosas de Vasconcelos EJ, Myler PJ, Kaysel Cruz A. Comparative transcriptomics in Leishmania braziliensis: disclosing differential gene expression of coding and putative noncoding RNAs across developmental stages. Rna Biology. PMID 30689499 DOI: 10.1080/15476286.2019.1574161  0.314
2017 Terrão MC, Rosas de Vasconcelos EJ, Defina TA, Myler PJ, Cruz AK. Disclosing 3' UTR cis-elements and putative partners involved in gene expression regulation in Leishmania spp. Plos One. 12: e0183401. PMID 28859096 DOI: 10.1371/journal.pone.0183401  0.331
2016 Parsons M, Myler PJ. Illuminating Parasite Protein Production by Ribosome Profiling. Trends in Parasitology. PMID 27061497 DOI: 10.1016/J.Pt.2016.03.005  0.304
2016 Goldman-Pinkovich A, Balno C, Strasser R, Zeituni-Molad M, Bendelak K, Rentsch D, Ephros M, Wiese M, Jardim A, Myler PJ, Zilberstein D. An Arginine Deprivation Response Pathway Is Induced in Leishmania during Macrophage Invasion. Plos Pathogens. 12: e1005494. PMID 27043018 DOI: 10.1371/journal.ppat.1005494  0.602
2016 Goldman-Pinkovich A, Balno C, Strasser R, Zeituni-Molad M, Bendelak K, Rentsch D, Ephros M, Wiese M, Jardim A, Myler PJ, Zilberstein D. An Arginine Deprivation Response Pathway Is Induced in Leishmania during Macrophage Invasion Plos Pathogens. 12. DOI: 10.1371/journal.ppat.1005494  0.601
2015 Schlisselberg D, Mazarib E, Inbar E, Rentsch D, Myler PJ, Zilberstein D. Size does matter: 18 amino acids at the N-terminal tip of an amino acid transporter in Leishmania determine substrate specificity. Scientific Reports. 5: 16289. PMID 26549185 DOI: 10.1038/srep16289  0.575
2015 Parsons M, Ramasamy G, Vasconcelos EJ, Jensen BC, Myler PJ. Advancing Trypanosoma brucei genome annotation through ribosome profiling and spliced leader mapping. Molecular and Biochemical Parasitology. 202: 1-10. PMID 26393539 DOI: 10.1016/J.Molbiopara.2015.09.002  0.336
2015 Phan IQ, Davies DR, Moretti NS, Shanmugam D, Cestari I, Anupama A, Fairman JW, Edwards TE, Stuart K, Schenkman S, Myler PJ. Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures. Acta Crystallographica. Section F, Structural Biology Communications. 71: 615-21. PMID 25961325 DOI: 10.1107/S2053230X15004185  0.461
2015 Genest PA, Baugh L, Taipale A, Zhao W, Jan S, van Luenen HG, Korlach J, Clark T, Luong K, Boitano M, Turner S, Myler PJ, Borst P. Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing. Nucleic Acids Research. 43: 2102-15. PMID 25662217 DOI: 10.1093/Nar/Gkv095  0.452
2015 Carnes J, Anupama A, Balmer O, Jackson A, Lewis M, Brown R, Cestari I, Desquesnes M, Gendrin C, Hertz-Fowler C, Imamura H, Ivens A, Ko?ený L, Lai DH, MacLeod A, ... ... Myler P, et al. Genome and phylogenetic analyses of trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty. Plos Neglected Tropical Diseases. 9: e3404. PMID 25568942 DOI: 10.1371/Journal.Pntd.0003404  0.455
2015 Schlisselberg D, Mazarib E, Inbar E, Rentsch D, Myler PJ, Zilberstein D. Size does matter: 18 amino acids at the N-terminal tip of an amino acid transporter in Leishmania determine substrate specificity Scientific Reports. 5. DOI: 10.1038/srep16289  0.575
2014 Sekar A, Merritt C, Baugh L, Stuart K, Myler PJ. Tb927.10.6900 encodes the glucosyltransferase involved in synthesis of base J in Trypanosoma brucei. Molecular and Biochemical Parasitology. 196: 9-11. PMID 25064607 DOI: 10.1016/J.Molbiopara.2014.07.005  0.49
2014 Tsigankov P, Gherardini PF, Helmer-Citterich M, Späth GF, Myler PJ, Zilberstein D. Regulation dynamics of Leishmania differentiation: deconvoluting signals and identifying phosphorylation trends. Molecular & Cellular Proteomics : McP. 13: 1787-99. PMID 24741111 DOI: 10.1074/Mcp.M114.037705  0.585
2012 van Luenen HG, Farris C, Jan S, Genest PA, Tripathi P, Velds A, Kerkhoven RM, Nieuwland M, Haydock A, Ramasamy G, Vainio S, Heidebrecht T, Perrakis A, Pagie L, van Steensel B, ... Myler PJ, et al. Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania. Cell. 150: 909-21. PMID 22939620 DOI: 10.1016/J.Cell.2012.07.030  0.439
2011 Parsons M, Myler PJ, Berriman M, Roos DS, Stuart KD. Identity crisis? The need for systematic gene IDs. Trends in Parasitology. 27: 183-4. PMID 21474380 DOI: 10.1016/J.Pt.2011.02.007  0.559
2011 Lahav T, Sivam D, Volpin H, Ronen M, Tsigankov P, Green A, Holland N, Kuzyk M, Borchers C, Zilberstein D, Myler PJ. Multiple levels of gene regulation mediate differentiation of the intracellular pathogen Leishmania Faseb Journal. 25: 515-525. PMID 20952481 DOI: 10.1096/Fj.10-157529  0.642
2009 Jensen BC, Sivam D, Kifer CT, Myler PJ, Parsons M. Widespread variation in transcript abundance within and across developmental stages of Trypanosoma brucei. Bmc Genomics. 10: 482. PMID 19840382 DOI: 10.1186/1471-2164-10-482  0.323
2009 Padilla-Mejía NE, Florencio-Martínez LE, Figueroa-Angulo EE, Manning-Cela RG, Hernández-Rivas R, Myler PJ, Martínez-Calvillo S. Gene organization and sequence analyses of transfer RNA genes in Trypanosomatid parasites. Bmc Genomics. 10: 232. PMID 19450263 DOI: 10.1186/1471-2164-10-232  0.362
2009 Panigrahi AK, Ogata Y, Zíková A, Anupama A, Dalley RA, Acestor N, Myler PJ, Stuart KD. A comprehensive analysis of Trypanosoma brucei mitochondrial proteome. Proteomics. 9: 434-50. PMID 19105172 DOI: 10.1002/pmic.200800477  0.494
2008 Fan E, Baker D, Fields S, Gelb MH, Buckner FS, Van Voorhis WC, Phizicky E, Dumont M, Mehlin C, Grayhack E, Sullivan M, Verlinde C, Detitta G, Meldrum DR, Merritt EA, ... ... Myler PJ, et al. Structural genomics of pathogenic protozoa: an overview. Methods in Molecular Biology (Clifton, N.J.). 426: 497-513. PMID 18542886 DOI: 10.1007/978-1-60327-058-8_33  0.654
2008 Rosenzweig D, Smith D, Myler PJ, Olafson RW, Zilberstein D. Post-translational modification of cellular proteins during Leishmania donovani differentiation. Proteomics. 8: 1843-50. PMID 18398879 DOI: 10.1002/Pmic.200701043  0.613
2008 Zíková A, Panigrahi AK, Dalley RA, Acestor N, Anupama A, Ogata Y, Myler PJ, Stuart K. Trypanosoma brucei mitochondrial ribosomes: affinity purification and component identification by mass spectrometry. Molecular & Cellular Proteomics : McP. 7: 1286-96. PMID 18364347 DOI: 10.1074/mcp.M700490-MCP200  0.444
2008 Panigrahi AK, Zíková A, Dalley RA, Acestor N, Ogata Y, Anupama A, Myler PJ, Stuart KD. Mitochondrial complexes in Trypanosoma brucei: a novel complex and a unique oxidoreductase complex. Molecular & Cellular Proteomics : McP. 7: 534-45. PMID 18073385 DOI: 10.1074/mcp.M700430-MCP200  0.447
2007 Saxena A, Lahav T, Holland N, Aggarwal G, Anupama A, Huang Y, Volpin H, Myler PJ, Zilberstein D. Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation. Molecular and Biochemical Parasitology. 152: 53-65. PMID 17204342 DOI: 10.1016/j.molbiopara.2006.11.011  0.663
2006 Arakaki T, Le Trong I, Phizicky E, Quartley E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Worthey E, Myler PJ, Kim D, Baker D, Hol WG, Merritt EA. Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 175-9. PMID 16511295 DOI: 10.1107/S1744309106005902  0.318
2006 Dobson DE, Scholtes LD, Myler PJ, Turco SJ, Beverley SM. Genomic organization and expression of the expanded SCG/L/R gene family of Leishmania major: internal clusters and telomeric localization of SCGs mediating species-specific LPG modifications. Molecular and Biochemical Parasitology. 146: 231-41. PMID 16464509 DOI: 10.1016/J.Molbiopara.2005.12.012  0.314
2005 Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G, Berriman M, Sisk E, Rajandream MA, Adlem E, Aert R, Anupama A, Apostolou Z, Attipoe P, Bason N, Bauser C, ... ... Myler PJ, et al. The genome of the kinetoplastid parasite, Leishmania major. Science (New York, N.Y.). 309: 436-42. PMID 16020728 DOI: 10.1126/Science.1112680  0.605
2005 El-Sayed NM, Myler PJ, Bartholomeu DC, Nilsson D, Aggarwal G, Tran AN, Ghedin E, Worthey EA, Delcher AL, Blandin G, Westenberger SJ, Caler E, Cerqueira GC, Branche C, Haas B, et al. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science (New York, N.Y.). 309: 409-15. PMID 16020725 DOI: 10.1126/Science.1112631  0.571
2005 El-Sayed NM, Myler PJ, Blandin G, Berriman M, Crabtree J, Aggarwal G, Caler E, Renauld H, Worthey EA, Hertz-Fowler C, Ghedin E, Peacock C, Bartholomeu DC, Haas BJ, Tran AN, et al. Comparative genomics of trypanosomatid parasitic protozoa. Science (New York, N.Y.). 309: 404-9. PMID 16020724 DOI: 10.1126/Science.1112181  0.578
2005 Martínez-Calvillo S, Stuart K, Myler PJ. Ploidy changes associated with disruption of two adjacent genes on Leishmania major chromosome 1. International Journal For Parasitology. 35: 419-29. PMID 15777918 DOI: 10.1016/J.Ijpara.2004.12.014  0.598
2005 Kim D, Chiurillo MA, El-Sayed N, Jones K, Santos MR, Porcile PE, Andersson B, Myler P, da Silveira JF, Ramírez JL. Telomere and subtelomere of Trypanosoma cruzi chromosomes are enriched in (pseudo)genes of retrotransposon hot spot and trans-sialidase-like gene families: the origins of T. cruzi telomeres. Gene. 346: 153-61. PMID 15716016 DOI: 10.1016/J.Gene.2004.10.014  0.315
2004 Sahin A, Lemercier G, Tetaud E, Espiau B, Myler P, Stuart K, Bakalara N, Merlin G. Trypanosomatid flagellum biogenesis: ARL-3A is involved in several species. Experimental Parasitology. 108: 126-33. PMID 15582509 DOI: 10.1016/J.Exppara.2004.07.010  0.464
2004 Zhou S, Kile A, Kvikstad E, Bechner M, Severin J, Forrest D, Runnheim R, Churas C, Anantharaman TS, Myler P, Vogt C, Ivens A, Stuart K, Schwartz DC. Shotgun optical mapping of the entire Leishmania major Friedlin genome. Molecular and Biochemical Parasitology. 138: 97-106. PMID 15500921 DOI: 10.1016/J.Molbiopara.2004.08.002  0.482
2004 Martínez-Calvillo S, Nguyen D, Stuart K, Myler PJ. Transcription initiation and termination on Leishmania major chromosome 3. Eukaryotic Cell. 3: 506-17. PMID 15075279 DOI: 10.1128/Ec.3.2.506-517.2004  0.553
2004 Monnerat S, Martinez-Calvillo S, Worthey E, Myler PJ, Stuart KD, Fasel N. Genomic organization and gene expression in a chromosomal region of Leishmania major. Molecular and Biochemical Parasitology. 134: 233-43. PMID 15003843 DOI: 10.1016/j.molbiopara.2003.12.004  0.597
2004 Ghedin E, Bringaud F, Peterson J, Myler P, Berriman M, Ivens A, Andersson B, Bontempi E, Eisen J, Angiuoli S, Wanless D, Von Arx A, Murphy L, Lennard N, Salzberg S, et al. Gene synteny and evolution of genome architecture in trypanosomatids. Molecular and Biochemical Parasitology. 134: 183-91. PMID 15003838 DOI: 10.1016/J.Molbiopara.2003.11.012  0.558
2003 Belli SI, Monnerat S, Schaff C, Masina S, Noll T, Myler PJ, Stuart K, Fasel N. Sense and antisense transcripts in the histone H1 (HIS-1) locus of Leishmania major. International Journal For Parasitology. 33: 965-75. PMID 12906880 DOI: 10.1016/S0020-7519(03)00126-7  0.584
2003 Worthey EA, Martinez-Calvillo S, Schnaufer A, Aggarwal G, Cawthra J, Fazelinia G, Fong C, Fu G, Hassebrock M, Hixson G, Ivens AC, Kiser P, Marsolini F, Rickel E, Rickell E, ... ... Myler PJ, et al. Leishmania major chromosome 3 contains two long convergent polycistronic gene clusters separated by a tRNA gene. Nucleic Acids Research. 31: 4201-10. PMID 12853638 DOI: 10.1093/Nar/Gkg469  0.582
2003 Saxena A, Worthey EA, Yan S, Leland A, Stuart KD, Myler PJ. Evaluation of differential gene expression in Leishmania major Friedlin procyclics and metacyclics using DNA microarray analysis. Molecular and Biochemical Parasitology. 129: 103-14. PMID 12798511 DOI: 10.1016/S0166-6851(03)00100-2  0.679
2003 Martínez-Calvillo S, Yan S, Nguyen D, Fox M, Stuart K, Myler PJ. Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region. Molecular Cell. 11: 1291-9. PMID 12769852 DOI: 10.1016/S1097-2765(03)00143-6  0.665
2003 Villa H, Otero Marcos AR, Reguera RM, Balaña-Fouce R, García-Estrada C, Pérez-Pertejo Y, Tekwani BL, Myler PJ, Stuart KD, Bjornsti MA, Ordóñez D. A novel active DNA topoisomerase I in Leishmania donovani. The Journal of Biological Chemistry. 278: 3521-6. PMID 12444094 DOI: 10.1074/Jbc.M203991200  0.485
2002 Dole VS, Myler PJ, Stuart KD, Madhubala R. Expression of biopterin transporter (BT1) protein in Leishmania. Fems Microbiology Letters. 208: 89-91. PMID 11934499 DOI: 10.1111/J.1574-6968.2002.TB11065.X  0.482
2002 Yan S, Martinez-Calvillo S, Schnaufer A, Sunkin S, Myler PJ, Stuart K. A low-background inducible promoter system in Leishmania donovani. Molecular and Biochemical Parasitology. 119: 217-23. PMID 11814573 DOI: 10.1016/S0166-6851(01)00418-2  0.647
2001 Myler PJ, Beverley SM, Cruz AK, Dobson DE, Ivens AC, McDonagh PD, Madhubala R, Martinez-Calvillo S, Ruiz JC, Saxena A, Sisk E, Sunkin SM, Worthey E, Yan S, Stuart KD. The Leishmania genome project: new insights into gene organization and function. Medical Microbiology and Immunology. 190: 9-12. PMID 11770120 DOI: 10.1007/S004300100070  0.698
2001 Jasmer DP, Roth J, Myler PJ. Cathepsin B-like cysteine proteases and Caenorhabditis elegans homologues dominate gene products expressed in adult Haemonchus contortus intestine Molecular and Biochemical Parasitology. 116: 159-169. PMID 11522349 DOI: 10.1016/S0166-6851(01)00312-7  0.343
2001 Martínez-Calvillo S, Sunkin SM, Yan S, Fox M, Stuart K, Myler PJ. Genomic organization and functional characterization of the Leishmania major Friedlin ribosomal RNA gene locus. Molecular and Biochemical Parasitology. 116: 147-57. PMID 11522348 DOI: 10.1016/S0166-6851(01)00310-3  0.679
2001 Sunkin SM, McDonagh P, Cunningham ML, Beverley SM, Stuart K, Myler PJ. Conservation of the LD1 region in Leishmania includes DNA implicated in LD1 amplification Molecular and Biochemical Parasitology. 113: 315-321. PMID 11295186 DOI: 10.1016/S0166-6851(01)00215-8  0.408
2001 Yan S, Myler PJ, Stuart K. Tetracycline regulated gene expression in Leishmania donovani. Molecular and Biochemical Parasitology. 112: 61-9. PMID 11166387 DOI: 10.1016/S0166-6851(00)00345-5  0.658
2000 Myler PJ, Sisk E, McDonagh PD, Martinez-Calvillo S, Schnaufer A, Sunkin SM, Yan S, Madhubala R, Ivens A, Stuart K. Genomic organization and gene function in Leishmania. Biochemical Society Transactions. 28: 527-31. PMID 11044368 DOI: 10.1042/Bst0280527  0.694
2000 Jiang DW, Ingersoll R, Myler PJ, Englund PT. Trypanosoma brucei: four tandemly linked genes for fatty acyl-CoA synthetases. Experimental Parasitology. 96: 16-22. PMID 11038316 DOI: 10.1006/Expr.2000.4547  0.32
2000 Myler PJ, Stuart KD. Recent developments from the Leishmania genome project Current Opinion in Microbiology. 3: 412-416. PMID 10972503 DOI: 10.1016/S1369-5274(00)00113-2  0.343
2000 Sunkin SM, Kiser P, Myler PJ, Stuart K. The size difference between leishmania major friedlin chromosome one homologues is localized to sub-telomeric repeats at one chromosomal end. Molecular and Biochemical Parasitology. 109: 1-15. PMID 10924752 DOI: 10.1016/S0166-6851(00)00215-2  0.486
2000 McDonagh PD, Myler PJ, Stuart K. The unusual gene organization of Leishmania major chromosome 1 may reflect novel transcription processes Nucleic Acids Research. 28: 2800-2803. PMID 10908338 DOI: 10.1093/Nar/28.14.2800  0.573
2000 Chiurillo MA, Beck AE, Devos T, Myler PJ, Stuart K, Ramirez JL. Cloning and characterization of Leishmania donovani telomeres Experimental Parasitology. 94: 248-258. PMID 10831393 DOI: 10.1006/Expr.2000.4499  0.509
1999 Ghosh A, Madhubala R, Myler PJ, Stuart KD. Leishmania donovani: Characterization and expression of ORFF, a gene amplified from the LDI locus Experimental Parasitology. 93: 225-230. PMID 10600448 DOI: 10.1006/expr.1999.4453  0.323
1999 Lemley C, Yan S, Dole VS, Madhubala R, Cunningham ML, Beverley SM, Myler PJ, Stuart KD. The Leishmania donovani LD1 locus gene ORFG encodes a biopterin transporter (BT1) Molecular and Biochemical Parasitology. 104: 93-105. PMID 10589984 DOI: 10.1016/S0166-6851(99)00132-2  0.676
1999 Jardim A, Bergeson SE, Shih S, Carter N, Lucas RW, Merlin G, Myler PJ, Stuart K, Ullman B. Xanthine phosphoribosyltransferase from Leishmania donovani. Molecular cloning, biochemical characterization, and genetic analysis. The Journal of Biological Chemistry. 274: 34403-10. PMID 10567419 DOI: 10.1074/Jbc.274.48.34403  0.551
1999 Yan S, Lodes MJ, Fox M, Myler PJ, Stuart K. Characterization of the Leishmania donovani ribosomal RNA promoter. Molecular and Biochemical Parasitology. 103: 197-210. PMID 10551363 DOI: 10.1016/S0166-6851(99)00126-7  0.681
1999 Myler PJ, Audleman L, deVos T, Hixson G, Kiser P, Lemley C, Magness C, Rickel E, Sisk E, Sunkin S, Swartzell S, Westlake T, Bastien P, Fu G, Ivens A, et al. Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes. Proceedings of the National Academy of Sciences of the United States of America. 96: 2902-6. PMID 10077609 DOI: 10.1073/Pnas.96.6.2902  0.594
1995 Lodes MJ, Merlin G, DeVos T, Ghosh A, Madhubala R, Myler PJ, Stuart K. Increased expression of LD1 genes transcribed by RNA polymerase I in Leishmania donovani as a result of duplication into the rRNA gene locus Molecular and Cellular Biology. 15: 6845-6853. PMID 8524251 DOI: 10.1128/Mcb.15.12.6845  0.572
1995 Riley GR, Myler PJ, Stuart K. Quantitation of RNA editing substrates, products and potential intermediates: Implications for developmental regulation Nucleic Acids Research. 23: 708-712. PMID 7534910 DOI: 10.1093/Nar/23.4.708  0.47
1995 Bastian LS, Lodes MJ, Myler PJ, Stuart K. Long‐Range Restriction Mapping of Megabase‐Sized Chromosomes that May Be Homologs in Trypanosoma brucei Journal of Eukaryotic Microbiology. 42: 278-282. PMID 7496386 DOI: 10.1111/J.1550-7408.1995.Tb01580.X  0.46
1994 Corell RA, Myler P, Stuart K. Trypanosoma brucei mitochondrial CR4 gene encodes an extensively edited mRNA with completely edited sequence only in bloodstream forms Molecular and Biochemical Parasitology. 64: 65-74. PMID 8078524 DOI: 10.1016/0166-6851(94)90135-X  0.538
1994 Myler PJ, Venkataraman GM, Lodes MJ, Stuart KD. A frequently amplified region in Leishmania contains a gene conserved in prokaryotes and eukaryotes Gene. 148: 187-193. PMID 7958944 DOI: 10.1016/0378-1119(94)90688-2  0.336
1994 Read LK, Wilson KD, Myler PJ, Stuart K. Editing of Trypanosoma brucei maxicircle CR5 mRNA generates variable carboxy terminal predicted protein sequences. Nucleic Acids Research. 22: 1489-95. PMID 7514788 DOI: 10.1093/Nar/22.8.1489  0.527
1993 Corell RA, Feagin JE, Riley GR, Strickland T, Guderian JA, Myler PJ, Stuart K. Trypanosoma brucei minicircles encode multiple guide RNAs which can direct editing of extensively overlapping sequences. Nucleic Acids Research. 21: 4313-20. PMID 8414987 DOI: 10.1093/Nar/21.18.4313  0.496
1993 Lodes MJ, Smiley BL, Stadnyk AW, Bennett JL, Myler PJ, Stuart K. Expression of a retroposon-like sequence upstream of the putative Trypanosoma brucei variant surface glycoprotein gene expression site promoter. Molecular and Cellular Biology. 13: 7036-7044. PMID 8413293 DOI: 10.1128/Mcb.13.11.7036  0.502
1993 Souza AE, Shu HH, Read LK, Myler PJ, Stuart KD. Extensive editing of CR2 maxicircle transcripts of Trypanosoma brucei predicts a protein with homology to a subunit of NADH dehydrogenase. Molecular and Cellular Biology. 13: 6832-40. PMID 8413276 DOI: 10.1128/MCB.13.11.6832  0.349
1993 Myler PJ, Glick D, Feagin JE, Morales TH, Stuart KD. Structural organization of the maxicircle variable region of Trypanosoma brucei: Identification of potential replication origins and topoisomerase II binding sites Nucleic Acids Research. 21: 687-694. PMID 8382804 DOI: 10.1093/nar/21.3.687  0.318
1992 Guilbride L, Myler PJ, Stuart K. Distribution and sequence divergence of LRV1 viruses among different Leishmania species Molecular and Biochemical Parasitology. 54: 101-104. PMID 1518522 DOI: 10.1016/0166-6851(92)90099-6  0.443
1992 Tripp CA, Wisdom WA, Myler PJ, Stuart KD. A multicopy, extrachromosomal DNA in Leishmania infantum contains two inverted repeats of the 27.5-kilobase LD1 sequence and encodes numerous transcripts Molecular and Biochemical Parasitology. 55: 39-50. PMID 1435875 DOI: 10.1016/0166-6851(92)90125-4  0.3
1992 Souza AE, Myler PJ, Stuart K. Maxicircle CR1 transcripts of Trypanosoma brucei are edited and developmentally regulated and encode a putative iron-sulfur protein homologous to an NADH dehydrogenase subunit. Molecular and Cellular Biology. 12: 2100-7. PMID 1373807 DOI: 10.1128/Mcb.12.5.2100  0.546
1991 Bhat GJ, Myler PJ, Stuart K. The two ATPase 6 mRNAs of Leishmania tarentolae differ at their 3′ ends Molecular and Biochemical Parasitology. 48: 139-149. PMID 1837067 DOI: 10.1016/0166-6851(91)90110-R  0.495
1991 Tripp CA, Myler PJ, Stuart K. A DNA sequence (LD1) which occurs in several genomic organizations in Leishmania Molecular and Biochemical Parasitology. 47: 151-160. PMID 1682806 DOI: 10.1016/0166-6851(91)90174-5  0.523
1990 Buening GM, Barbet A, Myler P, Mahan S, Nene V, McGuire TC. Characterization of a repetitive DNA probe for Babesia bigemina. Veterinary Parasitology. 36: 11-20. PMID 2382379 DOI: 10.1016/0304-4017(90)90089-T  0.52
1990 Smiley BL, Stadnyk AW, Myler PJ, Stuart K. The trypanosome leucine repeat gene in the variant surface glycoprotein expression site encodes a putative metal-binding domain and a region resembling protein-binding domains of yeast, Drosophila, and mammalian proteins. Molecular and Cellular Biology. 10: 6436-6444. PMID 2247064 DOI: 10.1128/Mcb.10.12.6436  0.493
1990 Smiley BL, Aline RF, Myler PJ, Stuart K. A retroposon in the 5' flank of a Trypanosoma brucei VSG gene lacks insertional terminal repeats Molecular and Biochemical Parasitology. 42: 143-151. PMID 2172817 DOI: 10.1016/0166-6851(90)90122-3  0.558
1989 Barbet AF, Myler PJ, Williams RO, McGuire TC. Shared surface epitopes among trypanosomes of the same serodeme expressing different variable surface glycoprotein genes Molecular and Biochemical Parasitology. 32: 191-199. PMID 2467204 DOI: 10.1016/0166-6851(89)90070-4  0.587
1988 Myler PJ, Aline RF, Scholler JK, Stuart KD. Multiple events associated with antigenic switching in Trypanosoma brucei Molecular and Biochemical Parasitology. 29: 227-241. PMID 2842674 DOI: 10.1016/0166-6851(88)90078-3  0.309
1987 Barbet AF, Palmer GH, Myler PJ, McGuire TC. Characterization of an immunoprotective protein complex of Anaplasma marginale by cloning and expression of the gene coding for polypeptide Am105L Infection and Immunity. 55: 2428-2435. PMID 2443451 DOI: 10.1128/Iai.55.10.2428-2435.1987  0.611
1985 Aline R, Macdonald G, Brown E, Allison J, Myler P, Rothwell V, Stuart K. (TAA)n within sequences flanking several intrachromosomal variant surface glycoprotein genes in Trypanosoma brucei Nucleic Acids Research. 13: 3161-3177. PMID 2987874 DOI: 10.1093/Nar/13.9.3161  0.562
1984 Myler P, Nelson RG, Agabian N, Stuart K. Two mechanisms of expression of a predominant variant antigen gene of Trypanosoma brucei. Nature. 309: 282-4. PMID 6325951 DOI: 10.1038/309282A0  0.554
1984 Saul A, Myler P, Schofield L, Kidson C. A high molecular weight antigen in Plasmodium falciparum recognized by inhibitory monoclonal antibodies. Parasite Immunology. 6: 39-50. PMID 6199717 DOI: 10.1111/j.1365-3024.1984.tb00780.x  0.536
Low-probability matches (unlikely to be authored by this person)
2013 Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D, Staker BL, Phan I, ... ... Myler PJ, et al. Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One. 8: e53851. PMID 23382856 DOI: 10.1371/Journal.Pone.0053851  0.297
2014 Jensen BC, Ramasamy G, Vasconcelos EJ, Ingolia NT, Myler PJ, Parsons M. Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei. Bmc Genomics. 15: 911. PMID 25331479 DOI: 10.1186/1471-2164-15-911  0.297
2005 Laurentino EC, Ruiz JC, Fazelinia G, Myler PJ, Degrave W, Alves-Ferreira M, Ribeiro JM, Cruz AK. A survey of Leishmania braziliensis genome by shotgun sequencing. Molecular and Biochemical Parasitology. 137: 81-6. PMID 15279954 DOI: 10.1016/J.MOLBIOPARA.2004.05.001  0.296
2015 Gillespie JJ, Phan IQ, Scheib H, Subramanian S, Edwards TE, Lehman SS, Piitulainen H, Sayeedur Rahman M, Rennoll-Bankert KE, Staker BL, Taira S, Stacy R, Myler PJ, Azad AF, Pulliainen AT. Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. Mbio. 6. PMID 26646013 DOI: 10.1128/Mbio.01867-15  0.296
2007 Kraemer SM, Kyes SA, Aggarwal G, Springer AL, Nelson SO, Christodoulou Z, Smith LM, Wang W, Levin E, Newbold CI, Myler PJ, Smith JD. Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates. Bmc Genomics. 8: 45. PMID 17286864 DOI: 10.1186/1471-2164-8-45  0.294
1989 Scholler JK, Myler PJ, Stuart KD. A novel telomeric gene conversion in Trypanosoma brucei Molecular and Biochemical Parasitology. 35: 11-19. PMID 2761571 DOI: 10.1016/0166-6851(89)90137-0  0.291
2009 Thomas S, Green A, Sturm NR, Campbell DA, Myler PJ. Histone acetylations mark origins of polycistronic transcription in Leishmania major. Bmc Genomics. 10: 152. PMID 19356248 DOI: 10.1186/1471-2164-10-152  0.284
2002 Buckner FS, Eastman RT, Nepomuceno-Silva JL, Speelmon EC, Myler PJ, Van Voorhis WC, Yokoyama K. Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major. Molecular and Biochemical Parasitology. 122: 181-8. PMID 12106872 DOI: 10.1016/S0166-6851(02)00099-3  0.281
2003 Aggarwal G, Worthey EA, McDonagh PD, Myler PJ. Importing statistical measures into Artemis enhances gene identification in the Leishmania genome project. Bmc Bioinformatics. 4: 23. PMID 12793912 DOI: 10.1186/1471-2105-4-23  0.279
2005 Worthey EA, Myler PJ. Protozoan genomes: gene identification and annotation. International Journal For Parasitology. 35: 495-512. PMID 15826642 DOI: 10.1016/J.IJPARA.2005.02.008  0.278
2016 Buchko GW, Clifton MC, Wallace EG, Atkins KA, Myler PJ. Backbone chemical shift assignments and secondary structure analysis of the U1 protein from the Bas-Congo virus. Biomolecular Nmr Assignments. PMID 27981424 DOI: 10.1007/S12104-016-9719-2  0.277
1994 Myler PJ, Lodes MJ, Merlin G, deVos T, Stuart KD. An amplified DNA element in Leishmania encodes potential integral membrane and nucleotide-binding proteins Molecular and Biochemical Parasitology. 66: 11-20. PMID 7984172 DOI: 10.1016/0166-6851(94)90031-0  0.272
2021 Morea EGO, Vasconcelos EJR, Alves CS, Giorgio S, Myler PJ, Langoni H, Azzalin CM, Cano MIN. Exploring TERRA during Leishmania major developmental cycle and continuous in vitro passages. International Journal of Biological Macromolecules. 174: 573-586. PMID 33548324 DOI: 10.1016/j.ijbiomac.2021.01.192  0.27
2007 Souza RT, Santos MR, Lima FM, El-Sayed NM, Myler PJ, Ruiz JC, da Silveira JF. New Trypanosoma cruzi repeated element that shows site specificity for insertion. Eukaryotic Cell. 6: 1228-38. PMID 17526721 DOI: 10.1128/Ec.00036-07  0.27
1988 Myler PJ, Aline RF, Scholler JK, Stuart KD. Changes in telomere length associated with antigenic variation in Trypanosoma brucei Molecular and Biochemical Parasitology. 29: 243-250. PMID 2842675 DOI: 10.1016/0166-6851(88)90079-5  0.269
1984 Myler PJ, Allison J, Agabian N, Stuart K. Antigenic variation in African trypanosomes by gene replacement or activation of alternate telomeres. Cell. 39: 203-11. PMID 6091912  0.268
2011 Phan I, Subramanian S, Olsen C, Edwards TE, Guo W, Zhang Y, Van Voorhis WC, Stewart LJ, Myler PJ. Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1123-8. PMID 21904061 DOI: 10.1107/S174430911102690X  0.266
1993 Souza AE, Myler PJ, Stuart KD. The alkane-inducible Candida maltosa ALI1 gene product is an NADH:ubiquinone oxidoreductase subunit homologue. Gene. 137: 349-50. PMID 8299970 DOI: 10.1016/0378-1119(93)90034-Z  0.265
2020 Ianiri G, Coelho MA, Ruchti F, Sparber F, McMahon TJ, Fu C, Bolejack M, Donovan O, Smutney H, Myler P, Dietrich F, Fox D, LeibundGut-Landmann S, Heitman J. HGT in the human and skin commensal : A bacterially derived flavohemoglobin is required for NO resistance and host interaction. Proceedings of the National Academy of Sciences of the United States of America. PMID 32576698 DOI: 10.1073/Pnas.2003473117  0.265
1994 Aline Jnr RF, Myler PJ, Gobright E, Stuart KD. Early expression of a Trypanosoma brucei VSG gene duplicated from an incomplete basic copy Journal of Eukaryotic Microbiology. 41: 71-78. PMID 8124269 DOI: 10.1111/j.1550-7408.1994.tb05937.x  0.264
1989 Aline RF, Myler PJ, Stuart KD. Trypanosoma brucei: Frequent loss of a telomeric variant surface glycoprotein gene Experimental Parasitology. 68: 8-16. PMID 2917631 DOI: 10.1016/0014-4894(89)90003-9  0.261
2006 Mehlin C, Boni E, Buckner FS, Engel L, Feist T, Gelb MH, Haji L, Kim D, Liu C, Mueller N, Myler PJ, Reddy JT, Sampson JN, Subramanian E, Van Voorhis WC, et al. Heterologous expression of proteins from Plasmodium falciparum: results from 1000 genes. Molecular and Biochemical Parasitology. 148: 144-60. PMID 16644028 DOI: 10.1016/J.Molbiopara.2006.03.011  0.26
2011 Edwards TE, Bryan CM, Leibly DJ, Dieterich SH, Abendroth J, Sankaran B, Sivam D, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structures of a putative ζ-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1038-43. PMID 21904047 DOI: 10.1107/S1744309111009493  0.256
2016 Gillespie JJ, Phan IQ, Driscoll TP, Guillotte ML, Lehman SS, Rennoll-Bankert KE, Subramanian S, Beier-Sexton M, Myler PJ, Rahman MS, Azad AF. The Rickettsia type IV secretion system: unrealized complexity mired by gene family expansion. Pathogens and Disease. PMID 27307105 DOI: 10.1093/Femspd/Ftw058  0.254
1993 Myler PJ. Molecular variation in trypanosomes. Acta Tropica. 53: 205-25. PMID 8100671 DOI: 10.1016/0001-706X(93)90030-F  0.251
2011 Subramanian S, Abendroth J, Phan IQ, Olsen C, Staker BL, Napuli A, Van Voorhis WC, Stacy R, Myler PJ. Structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Rickettsia prowazekii at 2.25 Å resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1118-22. PMID 21904060 DOI: 10.1107/S1744309111030673  0.251
2016 Antwi EB, Haanstra JR, Ramasamy G, Jensen B, Droll D, Rojas F, Minia I, Terrao M, Mercé C, Matthews K, Myler PJ, Parsons M, Clayton C. Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression. Bmc Genomics. 17: 306. PMID 27118143 DOI: 10.1186/S12864-016-2624-3  0.249
2017 Haft DH, Pierce PG, Mayclin SJ, Sullivan A, Gardberg AS, Abendroth J, Begley DW, Phan IQ, Staker BL, Myler PJ, Marathias VM, Lorimer DD, Edwards TE. Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Scientific Reports. 7: 41074. PMID 28120876 DOI: 10.1038/Srep41074  0.249
2014 Linford AS, Jiang NM, Edwards TE, Sherman NE, Van Voorhis WC, Stewart LJ, Myler PJ, Staker BL, Petri WA. Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Molecular and Biochemical Parasitology. 193: 33-44. PMID 24548880 DOI: 10.1016/J.Molbiopara.2014.01.003  0.245
2007 Sukumaran B, Jain M, Myler PJ, Stuart KD, Madhubala R. Creation of Tetracycline Regulatable Knockouts of ORFF Gene from the LD1 Locus of Leishmania donovani American Journal of Biochemistry and Biotechnology. 3: 207-215. DOI: 10.3844/AJBBSP.2007.207.215  0.241
2011 Begley DW, Davies DR, Hartley RC, Edwards TE, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Fragment screening of infectious disease targets in a structural genomics environment. Methods in Enzymology. 493: 533-56. PMID 21371605 DOI: 10.1016/B978-0-12-381274-2.00021-2  0.239
2011 Buchko GW, Edwards TE, Abendroth J, Arakaki TL, Law L, Napuli AJ, Hewitt SN, Van Voorhis WC, Stewart LJ, Staker BL, Myler PJ. Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1078-83. PMID 21904053 DOI: 10.1107/S1744309111011559  0.235
2017 Cuypers B, Domagalska MA, Meysman P, Muylder G, Vanaerschot M, Imamura H, Dumetz F, Verdonckt TW, Myler PJ, Ramasamy G, Laukens K, Dujardin JC. Multiplexed Spliced-Leader Sequencing: A high-throughput, selective method for RNA-seq in Trypanosomatids. Scientific Reports. 7: 3725. PMID 28623350 DOI: 10.1038/S41598-017-03987-0  0.235
2015 Buchko GW, Abendroth J, Clifton MC, Robinson H, Zhang Y, Hewitt SN, Staker BL, Edwards TE, Van Voorhis WC, Myler PJ. Structure of a CutA1 divalent-cation tolerance protein from Cryptosporidium parvum, the protozoal parasite responsible for cryptosporidiosis. Acta Crystallographica. Section F, Structural Biology Communications. 71: 522-30. PMID 25945704 DOI: 10.1107/S2053230X14028210  0.234
2005 Caruthers J, Zucker F, Worthey E, Myler PJ, Buckner F, Van Voorhuis W, Mehlin C, Boni E, Feist T, Luft J, Gulde S, Lauricella A, Kaluzhniy O, Anderson L, Le Trong I, et al. Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily. Protein Science : a Publication of the Protein Society. 14: 2887-94. PMID 16199669 DOI: 10.1110/Ps.051783005  0.233
1989 Myler PJ. Nucleotide and deduced amino acid sequence of the gp195 (MSA-1) gene from Plasmodium falciparum Palo Alto PLF-3/B11. Nucleic Acids Research. 17: 5401. PMID 2668887 DOI: 10.1093/NAR/17.13.5401  0.232
2018 Alcolea PJ, Alonso A, Baugh L, Paisie C, Ramasamy G, Sekar A, Sur A, Jiménez M, Molina R, Larraga V, Myler PJ. RNA-seq analysis reveals differences in transcript abundance between cultured and sand fly-derived Leishmania infantum promastigotes. Parasitology International. PMID 29609036 DOI: 10.1016/j.parint.2018.03.008  0.231
2011 Leeper T, Zhang S, Van Voorhis WC, Myler PJ, Varani G. Comparative analysis of glutaredoxin domains from bacterial opportunistic pathogens. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1141-7. PMID 21904064 DOI: 10.1107/S1744309111012346  0.23
1992 Stuart KD, Weeks R, Guilbride L, Myler PJ. Molecular organization of Leishmania RNA virus 1 Proceedings of the National Academy of Sciences of the United States of America. 89: 8596-8600. PMID 1382295 DOI: 10.1073/PNAS.89.18.8596  0.227
2010 Aslett M, Aurrecoechea C, Berriman M, Brestelli J, Brunk BP, Carrington M, Depledge DP, Fischer S, Gajria B, Gao X, Gardner MJ, Gingle A, Grant G, Harb OS, Heiges M, ... ... Myler PJ, et al. TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Research. 38: D457-62. PMID 19843604 DOI: 10.1093/Nar/Gkp851  0.223
2021 Ghafoori SM, Robles AM, Arada AM, Shirmast P, Dranow DM, Mayclin SJ, Lorimer DD, Myler PJ, Edwards TE, Kuhn ML, Forwood JK. Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1. Scientific Reports. 11: 9453. PMID 33947893 DOI: 10.1038/s41598-021-88672-z  0.223
2020 Santos JC, Vieira ML, Abendroth J, Lin T, Staker BL, Myler PJ, Nascimento ALTO. Structural analysis of CACHE domain of the McpA chemoreceptor from Leptospira interrogans. Biochemical and Biophysical Research Communications. PMID 33097187 DOI: 10.1016/j.bbrc.2020.10.013  0.223
2017 Moen SO, Edwards TE, Dranow DM, Clifton MC, Sankaran B, Van Voorhis WC, Sharma A, Manoil C, Staker BL, Myler PJ, Lorimer DD. Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Scientific Reports. 7: 223. PMID 28303005 DOI: 10.1038/S41598-017-00367-6  0.221
2012 Edwards TE, Liao R, Phan I, Myler PJ, Grundner C. Mycobacterium thermoresistibile as a source of thermostable orthologs of Mycobacterium tuberculosis proteins. Protein Science : a Publication of the Protein Society. 21: 1093-6. PMID 22544630 DOI: 10.1002/Pro.2084  0.219
2019 Filosa JN, Berry CT, Ruthel G, Beverley SM, Warren WC, Tomlinson C, Myler PJ, Dudkin EA, Povelones ML, Povelones M. Dramatic changes in gene expression in different forms of Crithidia fasciculata reveal potential mechanisms for insect-specific adhesion in kinetoplastid parasites. Plos Neglected Tropical Diseases. 13: e0007570. PMID 31356610 DOI: 10.1371/Journal.Pntd.0007570  0.217
2005 Padmanabhan PK, Mukherjee A, Singh S, Chattopadhyaya S, Gowri VS, Myler PJ, Srinivasan N, Madhubala R. Glyoxalase I from Leishmania donovani: a potential target for anti-parasite drug. Biochemical and Biophysical Research Communications. 337: 1237-48. PMID 16236261 DOI: 10.1016/J.Bbrc.2005.09.179  0.217
2014 Zhang WW, Ramasamy G, McCall LI, Haydock A, Ranasinghe S, Abeygunasekara P, Sirimanna G, Wickremasinghe R, Myler P, Matlashewski G. Genetic analysis of Leishmania donovani tropism using a naturally attenuated cutaneous strain. Plos Pathogens. 10: e1004244. PMID 24992200 DOI: 10.1371/journal.ppat.1004244  0.216
2014 Abendroth J, Ollodart A, Andrews ES, Myler PJ, Staker BL, Edwards TE, Arcus VL, Grundner C. Mycobacterium tuberculosis Rv2179c protein establishes a new exoribonuclease family with broad phylogenetic distribution. The Journal of Biological Chemistry. 289: 2139-47. PMID 24311791 DOI: 10.1074/Jbc.M113.525683  0.216
2018 Asojo OA, Dranow DM, Serbzhinskiy D, Subramanian S, Staker B, Edwards TE, Myler PJ. Crystal structure of chorismate mutase from Burkholderia thailandensis. Acta Crystallographica. Section F, Structural Biology Communications. 74: 294-299. PMID 29717997 DOI: 10.1107/S2053230X1800506X  0.215
2018 Asojo OA, Subramanian S, Abendroth J, Exley I, Lorimer DD, Edwards TE, Myler PJ. Crystal structure of chorismate mutase from Burkholderia phymatum. Acta Crystallographica. Section F, Structural Biology Communications. 74: 187-192. PMID 29633965 DOI: 10.1107/S2053230X18002868  0.214
2019 Buchko GW, Abendroth J, Robinson JI, Phan I, Myler PJ, Edwards TE. Structural diversity in the Mycobacteria DUF3349 superfamily. Protein Science : a Publication of the Protein Society. PMID 31658388 DOI: 10.1002/Pro.3758  0.213
2018 Dumais M, Davies DR, Lin T, Staker BL, Myler PJ, Van Voorhis WC. Structure and analysis of nucleoside diphosphate kinase from Borrelia burgdorferi prepared in a transition-state complex with ADP and vanadate moieties. Acta Crystallographica. Section F, Structural Biology Communications. 74: 373-384. PMID 29870023 DOI: 10.1107/S2053230X18007392  0.212
2019 Alcolea PJ, Alonso A, Molina R, Jiménez M, Myler PJ, Larraga V. Functional genomics in sand fly-derived Leishmania promastigotes. Plos Neglected Tropical Diseases. 13: e0007288. PMID 31071080 DOI: 10.1371/journal.pntd.0007288  0.211
2011 Buchko GW, Hewitt SN, Napuli AJ, Van Voorhis WC, Myler PJ. Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis, the etiological agent responsible for brucellosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1129-36. PMID 21904062 DOI: 10.1107/S1744309111006336  0.21
2011 Guild K, Zhang Y, Stacy R, Mundt E, Benbow S, Green A, Myler PJ. Wheat germ cell-free expression system as a pathway to improve protein yield and solubility for the SSGCID pipeline. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1027-31. PMID 21904045 DOI: 10.1107/S1744309111032143  0.209
2018 Abendroth J, Sankaran B, Myler PJ, Lorimer DD, Edwards TE. Ab initio structure solution of a proteolytic fragment using ARCIMBOLDO. Acta Crystallographica. Section F, Structural Biology Communications. 74: 530-535. PMID 30198884 DOI: 10.1107/S2053230X18010063  0.208
2019 Budzak J, Kerry LE, Aristodemou A, Hall BS, Witmer K, Kushwaha M, Davies C, Povelones ML, McDonald JR, Sur A, Myler PJ, Rudenko G. Dynamic colocalization of 2 simultaneously active expression sites within a single expression-site body in . Proceedings of the National Academy of Sciences of the United States of America. PMID 31358644 DOI: 10.1073/pnas.1905552116  0.206
2014 Vasconcelos EJ, Nunes VS, da Silva MS, Segatto M, Myler PJ, Cano MI. The putative Leishmania telomerase RNA (LeishTER) undergoes trans-splicing and contains a conserved template sequence. Plos One. 9: e112061. PMID 25391020 DOI: 10.1371/journal.pone.0112061  0.204
2012 Logan-Klumpler FJ, De Silva N, Boehme U, Rogers MB, Velarde G, McQuillan JA, Carver T, Aslett M, Olsen C, Subramanian S, Phan I, Farris C, Mitra S, Ramasamy G, Wang H, ... ... Myler PJ, et al. GeneDB--an annotation database for pathogens. Nucleic Acids Research. 40: D98-108. PMID 22116062 DOI: 10.1093/Nar/Gkr1032  0.203
2015 Edwards TE, Baugh L, Bullen J, Baydo RO, Witte P, Thompkins K, Phan IQ, Abendroth J, Clifton MC, Sankaran B, Van Voorhis WC, Myler PJ, Staker BL, Grundner C, Lorimer DD. Crystal structures of Mycobacterial MeaB and MMAA-like GTPases. Journal of Structural and Functional Genomics. 16: 91-9. PMID 25832174 DOI: 10.1007/S10969-015-9197-2  0.2
2007 Martínez-Calvillo S, Saxena A, Green A, Leland A, Myler PJ. Characterization of the RNA polymerase II and III complexes in Leishmania major. International Journal For Parasitology. 37: 491-502. PMID 17275824 DOI: 10.1016/j.ijpara.2006.11.019  0.2
2015 Buchko GW, Yee A, Semesi A, Myler PJ, Arrowsmith CH, Hui R. Solution-state NMR structure of the putative morphogene protein BolA (PFE0790c) from Plasmodium falciparum. Acta Crystallographica. Section F, Structural Biology Communications. 71: 514-21. PMID 25945703 DOI: 10.1107/S2053230X1402799X  0.198
2008 Myler PJ. Searching the Tritryp genomes for drug targets. Advances in Experimental Medicine and Biology. 625: 133-40. PMID 18365664 DOI: 10.1007/978-0-387-77570-8_11  0.196
1993 Tripp CA, Myler PJ, Stuart KD. Nucleotide sequence of a minicircle from Leishmania infantum Molecular and Biochemical Parasitology. 62: 319-320. PMID 8139625 DOI: 10.1016/0166-6851(93)90122-E  0.196
2013 Anderson BA, Wong IL, Baugh L, Ramasamy G, Myler PJ, Beverley SM. Kinetoplastid-specific histone variant functions are conserved in Leishmania major. Molecular and Biochemical Parasitology. 191: 53-7. PMID 24080031 DOI: 10.1016/J.Molbiopara.2013.09.005  0.195
2011 Ferrell M, Abendroth J, Zhang Y, Sankaran B, Edwards TE, Staker BL, Van Voorhis WC, Stewart LJ, Myler PJ. Structure of aldose reductase from Giardia lamblia. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1113-7. PMID 21904059 DOI: 10.1107/S1744309111030879  0.194
2011 Yates SP, Edwards TE, Bryan CM, Stein AJ, Van Voorhis WC, Myler PJ, Stewart LJ, Zheng J, Jia Z. Structural basis of the substrate specificity of bifunctional isocitrate dehydrogenase kinase/phosphatase. Biochemistry. 50: 8103-6. PMID 21870819 DOI: 10.1021/Bi200809P  0.194
2011 Abendroth J, Gardberg AS, Robinson JI, Christensen JS, Staker BL, Myler PJ, Stewart LJ, Edwards TE. SAD phasing using iodide ions in a high-throughput structural genomics environment. Journal of Structural and Functional Genomics. 12: 83-95. PMID 21359836 DOI: 10.1007/S10969-011-9101-7  0.194
2000 Dole VS, Raj VS, Ghosh A, Madhubala R, Myler PJ, Stuart KD. Immunization with recombinant LD1 antigens protects against experimental leishmaniasis. Vaccine. 19: 423-30. PMID 11027804 DOI: 10.1016/S0264-410X(00)00207-3  0.193
2017 Buchko GW, Echols N, Flynn EM, Ng H, Stephenson S, Kim HB, Myler PJ, Terwilliger TC, Alber T, Kim CY. Structural and biophysical characterization of the Mycobacterium tuberculosis protein Rv0577, a protein associated with neutral red staining of virulent tuberculosis strains and homolog of the Streptomyces coelicolor protein KbpA. Biochemistry. PMID 28692281 DOI: 10.1021/Acs.Biochem.7B00511  0.193
2015 Serbzhinskiy DA, Clifton MC, Sankaran B, Staker BL, Edwards TE, Myler PJ. Structure of an ADP-ribosylation factor, ARF1, from Entamoeba histolytica bound to Mg(2+)-GDP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 594-9. PMID 25945714 DOI: 10.1107/S2053230X15004677  0.192
2015 Edwards TE, Gardberg AS, Phan IQ, Zhang Y, Staker BL, Myler PJ, Lorimer DD. Structure of uridine diphosphate N-acetylglucosamine pyrophosphorylase from Entamoeba histolytica. Acta Crystallographica. Section F, Structural Biology Communications. 71: 560-5. PMID 25945709 DOI: 10.1107/S2053230X1500179X  0.19
1993 Myler PJ, Tripp CA, Thomas L, Venkataraman GM, Merlin G, Stuart KD. The LD1 amplified element from Leishmania infantum encodes a homolog of ribosomal protein L37 Molecular and Biochemical Parasitology. 62: 147-151. PMID 8114820 DOI: 10.1016/0166-6851(93)90192-Z  0.19
2010 Edwards TE, Phan I, Abendroth J, Dieterich SH, Masoudi A, Guo W, Hewitt SN, Kelley A, Leibly D, Brittnacher MJ, Staker BL, Miller SI, Van Voorhis WC, Myler PJ, Stewart LJ. Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. Plos One. 5. PMID 20862217 DOI: 10.1371/Journal.Pone.0012803  0.189
2013 Buchko GW, Abendroth J, Robinson H, Zhang Y, Hewitt SN, Edwards TE, Van Voorhis WC, Myler PJ. Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia. Journal of Structural and Functional Genomics. 14: 47-57. PMID 23709284 DOI: 10.1007/S10969-013-9155-9  0.189
2011 Begley DW, Hartley RC, Davies DR, Edwards TE, Leonard JT, Abendroth J, Burris CA, Bhandari J, Myler PJ, Staker BL, Stewart LJ. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. Journal of Structural and Functional Genomics. 12: 63-76. PMID 21359640 DOI: 10.1007/S10969-011-9102-6  0.188
2011 Stacy R, Begley DW, Phan I, Staker BL, Van Voorhis WC, Varani G, Buchko GW, Stewart LJ, Myler PJ. Structural genomics of infectious disease drug targets: the SSGCID. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 979-84. PMID 21904037 DOI: 10.1107/S1744309111029204  0.188
2016 Dubey R, Staker BL, Foe IT, Bogyo M, Myler PJ, Ngô HM, Gubbels MJ. Membrane skeletal association and post-translational allosteric regulation of Toxoplasma gondii GAPDH1. Molecular Microbiology. PMID 27859784 DOI: 10.1111/Mmi.13577  0.187
1998 Allen TE, Heidmann S, Reed R, Myler PJ, Göringer HU, Stuart KD. Association of guide RNA binding protein gBP21 with active RNA editing complexes in Trypanosoma brucei. Molecular and Cellular Biology. 18: 6014-22. PMID 9742118 DOI: 10.1128/Mcb.18.10.6014  0.186
2011 Jaffe EK, Shanmugam D, Gardberg A, Dieterich S, Sankaran B, Stewart LJ, Myler PJ, Roos DS. Crystal structure of Toxoplasma gondii porphobilinogen synthase: insights on octameric structure and porphobilinogen formation. The Journal of Biological Chemistry. 286: 15298-307. PMID 21383008 DOI: 10.1074/jbc.M111.226225  0.184
2019 Myler PJ, McDonald JA, Alcolea PJ, Sur A. Quantitative RNA Analysis Using RNA-Seq. Methods in Molecular Biology (Clifton, N.J.). 1971: 95-108. PMID 30980299 DOI: 10.1007/978-1-4939-9210-2_4  0.184
2014 Martin JL, Yates PA, Soysa R, Alfaro JF, Yang F, Burnum-Johnson KE, Petyuk VA, Weitz KK, Camp DG, Smith RD, Wilmarth PA, David LL, Ramasamy G, Myler PJ, Carter NS. Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovani. Plos Pathogens. 10: e1003938. PMID 24586154 DOI: 10.1371/Journal.Ppat.1003938  0.182
2006 Robien MA, Bosch J, Buckner FS, Van Voorhis WC, Worthey EA, Myler P, Mehlin C, Boni EE, Kalyuzhniy O, Anderson L, Lauricella A, Gulde S, Luft JR, DeTitta G, Caruthers JM, et al. Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site. Proteins. 62: 570-7. PMID 16345073 DOI: 10.1002/Prot.20801  0.181
2016 Naqvi KF, Staker BL, Dobson RC, Serbzhinskiy D, Sankaran B, Myler PJ, Hudson AO. Cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the human pathogenic bacterium Bartonella henselae strain Houston-1 at 2.1 Å resolution. Acta Crystallographica. Section F, Structural Biology Communications. 72: 2-9. PMID 26750477 DOI: 10.1107/S2053230X15023213  0.181
2015 Abendroth J, Choi R, Wall A, Clifton MC, Lukacs CM, Staker BL, Van Voorhis W, Myler P, Lorimer DD, Edwards TE. Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallographica. Section F, Structural Biology Communications. 71: 566-71. PMID 25945710 DOI: 10.1107/S2053230X15001831  0.181
2016 Cala AR, Nadeau MT, Abendroth J, Staker BL, Reers AR, Weatherhead AW, Dobson RC, Myler PJ, Hudson AO. The crystal structure of dihydrodipicolinate reductase from the human-pathogenic bacterium Bartonella henselae strain Houston-1 at 2.3 Å resolution. Acta Crystallographica. Section F, Structural Biology Communications. 72: 885-891. PMID 27917836 DOI: 10.1107/S2053230X16018525  0.179
2017 Abendroth J, Frando A, Phan IQ, Staker BL, Myler PJ, Edwards TE, Grundner C. Mycobacterium tuberculosis Rv3651 is a triple sensor-domain protein. Protein Science : a Publication of the Protein Society. PMID 29119630 DOI: 10.1002/Pro.3343  0.179
2015 Haydock A, Terrao M, Sekar A, Ramasamy G, Baugh L, Myler PJ. RNA-seq approaches for determining mRNA abundance in Leishmania Methods in Molecular Biology. 1201: 207-219. PMID 25388116 DOI: 10.1007/978-1-4939-1438-8_12  0.179
2006 Caruthers J, Bosch J, Buckner F, Van Voorhis W, Myler P, Worthey E, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Kalyuzhniy O, Anderson L, Zucker F, Soltis M, et al. Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum. Proteins. 62: 338-42. PMID 16304640 DOI: 10.1002/prot.20764  0.179
2021 Tillery L, Barrett K, Goldstein J, Lassner JW, Osterhout B, Tran NL, Xu L, Young RM, Craig J, Chun I, Dranow DM, Abendroth J, Delker SL, Davies DR, Mayclin SJ, ... ... Myler PJ, et al. Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba. Plos One. 16: e0241738. PMID 33760815 DOI: 10.1371/journal.pone.0241738  0.177
2011 Bauman A, Higdon R, Rapson S, Loiue B, Hogan J, Stacy R, Napuli A, Guo W, van Voorhis W, Roach J, Lu V, Landorf E, Stewart E, Kolker N, Collart F, ... Myler P, et al. Design and initial characterization of the SC-200 proteomics standard mixture. Omics : a Journal of Integrative Biology. 15: 73-82. PMID 21250827 DOI: 10.1089/Omi.2010.0118  0.175
2019 Barrett K, Michaels S, Navaluna E, Siddaramaiah L, Wood G, Phan I, Zhang Z, Staker B, Subramanian S, Totten P, Soge O, Myler P, Suchland R, Barrett L, Voorhis WV, et al. P316 Structure-based drug design for neisseria gonorrhoeae, chlamydia trachomatis, and mycoplasma genitalium Sexually Transmitted Infections. 95. DOI: 10.1136/Sextrans-2019-Sti.427  0.175
2015 Lorimer DD, Choi R, Abramov A, Nakazawa Hewitt S, Gardberg AS, Van Voorhis WC, Staker BL, Myler PJ, Edwards TE. Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 572-6. PMID 25945711 DOI: 10.1107/S2053230X1500237X  0.17
2021 Rodarte JV, Abendroth J, Edwards TE, Lorimer DD, Staker BL, Zhang S, Myler PJ, McLaughlin KJ. Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis. Acta Crystallographica. Section F, Structural Biology Communications. 77: 54-60. PMID 33620038 DOI: 10.1107/S2053230X21001497  0.17
2014 Phan IQ, Stacy R, Myler PJ. Selecting targets from eukaryotic parasites for structural genomics and drug discovery. Methods in Molecular Biology (Clifton, N.J.). 1140: 53-9. PMID 24590708 DOI: 10.1007/978-1-4939-0354-2_4  0.168
2011 Begley DW, Edwards TE, Raymond AC, Smith ER, Hartley RC, Abendroth J, Sankaran B, Lorimer DD, Myler PJ, Staker BL, Stewart LJ. Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1070-7. PMID 21904052 DOI: 10.1107/S1744309111029009  0.167
2015 Clifton MC, Bruhn JF, Atkins K, Webb TL, Baydo RO, Raymond A, Lorimer DD, Edwards TE, Myler PJ, Saphire EO. High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus. The Journal of Infectious Diseases. 212: S167-71. PMID 25957961 DOI: 10.1093/Infdis/Jiv090  0.166
2014 Moreno MA, Abramov A, Abendroth J, Alonso A, Zhang S, Alcolea PJ, Edwards T, Lorimer D, Myler PJ, Larraga V. Structure of tyrosine aminotransferase from Leishmania infantum. Acta Crystallographica. Section F, Structural Biology Communications. 70: 583-7. PMID 24817714 DOI: 10.1107/S2053230X14007845  0.166
2015 Baugh L, Phan I, Begley DW, Clifton MC, Armour B, Dranow DM, Taylor BM, Muruthi MM, Abendroth J, Fairman JW, Fox D, Dieterich SH, Staker BL, Gardberg AS, Choi R, ... ... Myler PJ, et al. Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinburgh, Scotland). 95: 142-8. PMID 25613812 DOI: 10.1016/J.Tube.2014.12.003  0.166
2011 Zhang Y, Edwards TE, Begley DW, Abramov A, Thompkins KB, Ferrell M, Guo WJ, Phan I, Olsen C, Napuli A, Sankaran B, Stacy R, Van Voorhis WC, Stewart LJ, Myler PJ. Structure of nitrilotriacetate monooxygenase component B from Mycobacterium thermoresistibile. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1100-5. PMID 21904057 DOI: 10.1107/S1744309111012541  0.165
1996 Corell RA, Read LK, Riley GR, Nellissery JK, Allen TE, Kable ML, Wachal MD, Seiwert SD, Myler PJ, Stuart KD. Complexes from Trypanosoma brucei that exhibit deletion editing and other editing-associated properties. Molecular and Cellular Biology. 16: 1410-8. PMID 8657114 DOI: 10.1128/MCB.16.4.1410  0.165
2014 Begley DW, Fox D, Jenner D, Juli C, Pierce PG, Abendroth J, Muruthi M, Safford K, Anderson V, Atkins K, Barnes SR, Moen SO, Raymond AC, Stacy R, Myler PJ, et al. A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrobial Agents and Chemotherapy. 58: 1458-67. PMID 24366729 DOI: 10.1128/Aac.01875-13  0.164
2011 Begley DW, Davies DR, Hartley RC, Hewitt SN, Rychel AL, Myler PJ, Van Voorhis WC, Staker BL, Stewart LJ. Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1060-9. PMID 21904051 DOI: 10.1107/S1744309111014436  0.164
2007 Jain M, Dole VS, Myler PJ, Stuart KD, Madhubala R. Role of Biopterin Transporter (BT1) Gene on Growth and Infectivity of Leishmania American Journal of Biochemistry and Biotechnology. 3: 199-206. DOI: 10.3844/AJBBSP.2007.199.206  0.162
2011 Edwards TE, Leibly DJ, Bhandari J, Statnekov JB, Phan I, Dieterich SH, Abendroth J, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1032-7. PMID 21904046 DOI: 10.1107/S1744309111004349  0.162
2021 Phan IQ, Subramanian S, Kim D, Murphy M, Pettie D, Carter L, Anishchenko I, Barrett LK, Craig J, Tillery L, Shek R, Harrington WE, Koelle DM, Wald A, Veesler D, ... ... Myler PJ, et al. In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19. Scientific Reports. 11: 4290. PMID 33619344 DOI: 10.1038/s41598-021-83730-y  0.162
2019 Schlott AC, Mayclin S, Reers AR, Coburn-Flynn O, Bell AS, Green J, Knuepfer E, Charter D, Bonnert R, Campo B, Burrows J, Lyons-Abbott S, Staker BL, Chung CW, Myler PJ, et al. Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors. Cell Chemical Biology. PMID 31080074 DOI: 10.1016/J.Chembiol.2019.03.015  0.161
2014 Clifton MC, Kirchdoerfer RN, Atkins K, Abendroth J, Raymond A, Grice R, Barnes S, Moen S, Lorimer D, Edwards TE, Myler PJ, Saphire EO. Structure of the Reston ebolavirus VP30 C-terminal domain. Acta Crystallographica. Section F, Structural Biology Communications. 70: 457-60. PMID 24699737 DOI: 10.1107/S2053230X14003811  0.158
2012 Cadag E, Tarczy-Hornoch P, Myler PJ. Learning virulent proteins from integrated query networks. Bmc Bioinformatics. 13: 321. PMID 23198735 DOI: 10.1186/1471-2105-13-321  0.154
2010 Buchko GW, Robinson H, Abendroth J, Staker BL, Myler PJ. Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): profound asymmetry in the crystal structure of the 'open' state. Biochemical and Biophysical Research Communications. 394: 1012-7. PMID 20331978 DOI: 10.1016/J.Bbrc.2010.03.112  0.153
2009 Myler PJ, Stacy R, Stewart L, Staker BL, Van Voorhis WC, Varani G, Buchko GW. The Seattle Structural Genomics Center for Infectious Disease (SSGCID). Infectious Disorders Drug Targets. 9: 493-506. PMID 19594426 DOI: 10.2174/187152609789105687  0.152
2009 Van Voorhis WC, Hol WG, Myler PJ, Stewart LJ. The role of medical structural genomics in discovering new drugs for infectious diseases. Plos Computational Biology. 5: e1000530. PMID 19855826 DOI: 10.1371/journal.pcbi.1000530  0.152
2003 Zhang WW, Mendez S, Ghosh A, Myler P, Ivens A, Clos J, Sacks DL, Matlashewski G. Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection. The Journal of Biological Chemistry. 278: 35508-15. PMID 12829719 DOI: 10.1074/Jbc.M305030200  0.152
2011 Clifton MC, Abendroth J, Edwards TE, Leibly DJ, Gillespie AK, Ferrell M, Dieterich SH, Exley I, Staker BL, Myler PJ, Van Voorhis WC, Stewart LJ. Structure of the cystathionine γ-synthase MetB from Mycobacterium ulcerans. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1154-8. PMID 21904066 DOI: 10.1107/S1744309111029575  0.151
2010 Gerdts CJ, Stahl GL, Napuli A, Staker B, Abendroth J, Edwards TE, Myler P, Van Voorhis W, Nollert P, Stewart LJ. Nanovolume optimization of protein crystal growth using the microcapillary protein crystallization system. Journal of Applied Crystallography. 43: 1078-1083. PMID 22477778 DOI: 10.1107/S0021889810027378  0.149
2014 Moen SO, Abendroth J, Fairman JW, Baydo RO, Bullen J, Kirkwood JL, Barnes SR, Raymond AC, Begley DW, Henkel G, McCormack K, Tam VC, Phan I, Staker BL, Stacy R, ... Myler PJ, et al. Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1. Scientific Reports. 4: 5944. PMID 25089892 DOI: 10.1038/Srep05944  0.149
2010 Buchko GW, Phan I, Myler PJ, Terwilliger TC, Kim CY. Inaugural structure from the DUF3349 superfamily of proteins, Mycobacterium tuberculosis Rv0543c. Archives of Biochemistry and Biophysics. 506: 150-6. PMID 21144816 DOI: 10.1016/j.abb.2010.12.001  0.148
2011 Nguyen TN, Abendroth J, Leibly DJ, Le KP, Guo W, Kelley A, Stewart L, Myler PJ, Van Voorhis WC. Structure of triosephosphate isomerase from Cryptosporidium parvum. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1095-9. PMID 21904056 DOI: 10.1107/S1744309111019178  0.146
2015 Stacy R, Anderson WF, Myler PJ. Structural Genomics Support for Infectious Disease Drug Design. Acs Infectious Diseases. 1: 127-129. PMID 25984568 DOI: 10.1021/id500048p  0.145
2015 Staker BL, Buchko GW, Myler PJ. Recent contributions of structure-based drug design to the development of antibacterial compounds. Current Opinion in Microbiology. 27: 133-8. PMID 26458180 DOI: 10.1016/j.mib.2015.09.003  0.143
2011 Abendroth J, Sankaran B, Edwards TE, Gardberg AS, Dieterich S, Bhandari J, Napuli AJ, Van Voorhis WC, Staker BL, Myler PJ, Stewart LJ. BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1106-12. PMID 21904058 DOI: 10.1107/S1744309111010220  0.142
2015 Lambertz U, Oviedo Ovando ME, Vasconcelos EJ, Unrau PJ, Myler PJ, Reiner NE. Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging. Bmc Genomics. 16: 151. PMID 25764986 DOI: 10.1186/S12864-015-1260-7  0.142
2016 Helgren TR, Chen C, Wangtrakuldee P, Edwards TE, Staker BL, Abendroth J, Sankaran B, Housley NA, Myler PJ, Audia JP, Horn JR, Hagen TJ. Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents. Bioorganic & Medicinal Chemistry. PMID 28089350 DOI: 10.1016/J.Bmc.2016.11.013  0.14
1987 Myler P, Coppel R. Workshop 1F: Protozoan antigens and genes International Journal For Parasitology. 17: 1006. DOI: 10.1016/0020-7519(87)90199-8  0.14
2006 Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, DeTitta G, Luft JR, Lauricella A, Gulde S, Anderson LA, Kalyuzhniy O, et al. Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. Journal of Medicinal Chemistry. 49: 5939-46. PMID 17004709 DOI: 10.1021/Jm060429M  0.137
2011 Buchko GW, Kim CY, Terwilliger TC, Myler PJ. Solution structure of Rv2377c-founding member of the MbtH-like protein family. Tuberculosis (Edinburgh, Scotland). 90: 245-51. PMID 20434955 DOI: 10.1016/j.tube.2010.04.002  0.135
1984 Myler P, Saul A, Kidson C. The synthesis and fate of stage-specific proteins in Plasmodium falciparum cultures. Molecular and Biochemical Parasitology. 9: 37-45. PMID 6366545 DOI: 10.1016/0166-6851(83)90055-5  0.135
2019 Harupa A, de Las Heras L, Colmenarejo G, Lyons-Abbott S, Reers A, Caballero Hernandez I, Chung CW, Charter D, Myler PJ, Fernandez-Menendez RM, Calderon F, Palomo S, Rodriguez B, Berlanga M, Herreros-Avilés E, et al. Identification of selective inhibitors of Plasmodium N-myristoyltransferase by high-throughput screening. Journal of Medicinal Chemistry. PMID 31850752 DOI: 10.1021/Acs.Jmedchem.9B01343  0.134
2015 Moen SO, Fairman JW, Barnes SR, Sullivan A, Nakazawa-Hewitt S, Van Voorhis WC, Staker BL, Lorimer DD, Myler PJ, Edwards TE. Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 609-14. PMID 25945716 DOI: 10.1107/S2053230X15006883  0.134
2019 Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, ... ... Myler PJ, et al. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30894487 DOI: 10.1073/Pnas.1814685116  0.13
2014 Moreno MA, Alonso A, Alcolea PJ, Abramov A, de Lacoba MG, Abendroth J, Zhang S, Edwards T, Lorimer D, Myler PJ, Larraga V. Tyrosine aminotransferase from Leishmania infantum: A new drug target candidate. International Journal For Parasitology. Drugs and Drug Resistance. 4: 347-54. PMID 25516846 DOI: 10.1016/J.Ijpddr.2014.06.001  0.128
1982 Myler P, Chiu S, Upcroft J, Castelino D, Kidson C. Immunoprecipitation of biosynthetically labelled, stage-specific proteins from cultured Plasmodium falciparum using inhibitory human sera. The Australian Journal of Experimental Biology and Medical Science. 60: 91-6. PMID 7046718 DOI: 10.1038/ICB.1982.7  0.127
2020 Xie Y, Feng Y, Di Capua A, Mak T, Buchko GW, Myler PJ, Liu M, Quinn RJ. A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466. Marine Drugs. 18. PMID 32150903 DOI: 10.3390/md18030149  0.126
1991 Bhat GJ, Lodes MJ, Myler PJ, Stuart KD. A simple method for cloning blunt ended DNA fragments Nucleic Acids Research. 19: 398. DOI: 10.1093/nar/19.2.398  0.125
2018 Buchko GW, Hewitt SN, Van Voorhis WC, Myler PJ. Solution NMR structures of oxidized and reduced Ehrlichia chaffeensis thioredoxin: NMR-invisible structure owing to backbone dynamics. Acta Crystallographica. Section F, Structural Biology Communications. 74: 46-56. PMID 29372907 DOI: 10.1107/S2053230X1701799X  0.124
2020 Shaheen S, Barrett KF, Subramanian S, Arnold SLM, Laureanti JA, Myler PJ, Van Voorhis WC, Buchko GW. Solution structure for an Encephalitozoon cuniculi adrenodoxin-like protein in the oxidized state. Protein Science : a Publication of the Protein Society. PMID 31912584 DOI: 10.1002/pro.3818  0.124
2011 Buchko GW, Hewitt SN, Napuli AJ, Van Voorhis WC, Myler PJ. Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1148-53. PMID 21904065 DOI: 10.1107/S1744309111008189  0.123
2019 Patterson EI, Nanson JD, Abendroth J, Bryan C, Sankaran B, Myler PJ, Forwood JK. Structural Characterisation of β-Ketoacyl ACP Synthase I Bound to Platencin and Fragment Screening Molecules at Two Substrate Binding Sites. Proteins. PMID 31237717 DOI: 10.1002/prot.25765  0.122
2011 Davies DR, Staker BL, Abendroth JA, Edwards TE, Hartley R, Leonard J, Kim H, Rychel AL, Hewitt SN, Myler PJ, Stewart LJ. An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1044-50. PMID 21904048 DOI: 10.1107/S1744309111030405  0.119
1992 Read LK, Myler PJ, Stuart K. Extensive editing of both processed and preprocessed maxicircle CR6 transcripts in Trypanosoma brucei. Journal of Biological Chemistry. 267: 1123-1128. DOI: 10.1016/s0021-9258(18)48405-0  0.114
2021 Buchko GW, Zhou M, Craig JK, Van Voorhis WC, Myler PJ. Backbone chemical shift assignments for the SARS-CoV-2 non-structural protein Nsp9: intermediate (ms - μs) dynamics in the C-terminal helix at the dimer interface. Biomolecular Nmr Assignments. PMID 33392924 DOI: 10.1007/s12104-020-09992-1  0.111
1992 Weeks R, Aline RF, Myler PJ, Stuart K. LRV1 viral particles in Leishmania guyanensis contain double-stranded or single-stranded RNA. Journal of Virology. 66: 1389-93. PMID 1738198 DOI: 10.1128/JVI.66.3.1389-1393.1992  0.11
1999 Raj VS, Ghosh A, Dole VS, Madhubala R, Myler PJ, Stuart KD. Serodiagnosis of leishmaniasis with recombinant ORFF antigen. The American Journal of Tropical Medicine and Hygiene. 61: 482-7. PMID 10497995 DOI: 10.4269/AJTMH.1999.61.482  0.109
2020 Barrett KF, Dranow DM, Phan I, Michaels SA, Shaheen S, Navaluna ED, Craig JK, Tillery LM, Choi R, Edwards TE, Conrady DG, Abendroth J, Horanyi PS, Lorimer DD, Van Voorhis WC, ... ... Myler P, et al. Structures of glyceraldehyde 3-phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis. Protein Science : a Publication of the Protein Society. PMID 31930578 DOI: 10.1002/Pro.3824  0.103
2018 Helgren TR, Seven ES, Chen C, Edwards TE, Staker BL, Abendroth J, Myler PJ, Horn JR, Hagen TJ. The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications. Bioorganic & Medicinal Chemistry Letters. PMID 29551481 DOI: 10.1016/J.Bmcl.2018.03.002  0.103
2009 Buchko GW, Hewitt SN, Napuli AJ, Van Voorhis WC, Myler PJ. Backbone and side chain (1)H, (13)C, and (15)N NMR assignments for the organic hydroperoxide resistance protein (Ohr) from Burkholderia pseudomallei. Biomolecular Nmr Assignments. 3: 163-6. PMID 19888681 DOI: 10.1007/s12104-009-9165-5  0.102
2013 Zhang Z, Jakkaraju S, Blain J, Gogol K, Zhao L, Hartley RC, Karlsson CA, Staker BL, Edwards TE, Stewart LJ, Myler PJ, Clare M, Begley DW, Horn JR, Hagen TJ. Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Bioorganic & Medicinal Chemistry Letters. 23: 6860-3. PMID 24157367 DOI: 10.1016/J.Bmcl.2013.09.101  0.102
2010 Yamada S, Hatta M, Staker BL, Watanabe S, Imai M, Shinya K, Sakai-Tagawa Y, Ito M, Ozawa M, Watanabe T, Sakabe S, Li C, Kim JH, Myler PJ, Phan I, et al. Biological and structural characterization of a host-adapting amino acid in influenza virus. Plos Pathogens. 6: e1001034. PMID 20700447 DOI: 10.1371/Journal.Ppat.1001034  0.099
2016 Nakazawa Hewitt S, Dranow DM, Horst BG, Abendroth JA, Forte B, Hallyburton I, Jansen C, Baragana B, Choi R, Rivas KL, Hulverson MA, Dumais M, Edwards TE, Lorimer DD, Fairlamb AH, ... ... Myler PJ, et al. Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. Acs Infectious Diseases. PMID 27798837 DOI: 10.1021/Acsinfecdis.6B00078  0.099
2020 Elnaas AR, Grice D, Han J, Feng Y, Capua AD, Mak T, Laureanti JA, Buchko GW, Myler PJ, Cook G, Quinn RJ, Liu M. Discovery of a Natural Product That Binds to the Protein Rv1466 Using Native Mass Spectrometry. Molecules (Basel, Switzerland). 25. PMID 32455540 DOI: 10.3390/molecules25102384  0.097
2010 Abendroth J, McCormick MS, Edwards TE, Staker B, Loewen R, Gifford M, Rifkin J, Mayer C, Guo W, Zhang Y, Myler P, Kelley A, Analau E, Hewitt SN, Napuli AJ, et al. X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source. Journal of Structural and Functional Genomics. 11: 91-100. PMID 20364333 DOI: 10.1007/S10969-010-9087-6  0.096
2011 Edwards TE, Abramov AB, Smith ER, Baydo RO, Leonard JT, Leibly DJ, Thompkins KB, Clifton MC, Gardberg AS, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. Bmc Structural Biology. 11: 39. PMID 21995815 DOI: 10.1186/1472-6807-11-39  0.091
2015 Buchko GW, Edwards TE, Hewitt SN, Phan IQ, Van Voorhis WC, Miller SI, Myler PJ. Backbone chemical shift assignments for the sensor domain of the Burkholderia pseudomallei histidine kinase RisS: "missing" resonances at the dimer interface. Biomolecular Nmr Assignments. PMID 25957069 DOI: 10.1007/S12104-015-9614-2  0.09
2018 Buchko GW, Pulavarti SVSRK, Ovchinnikov V, Shaw EA, Rettie SA, Myler PJ, Karplus M, Szyperski T, Baker D, Bahl CD. Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides. Protein Science : a Publication of the Protein Society. PMID 30152054 DOI: 10.1002/Pro.3453  0.088
2012 Myler PJ, Stacy R. A new drug for an old bug. Chemistry & Biology. 19: 1499-500. PMID 23261593 DOI: 10.1016/j.chembiol.2012.12.003  0.086
2013 Mittra B, Cortez M, Haydock A, Ramasamy G, Myler PJ, Andrews NW. Iron uptake controls the generation of Leishmania infective forms through regulation of ROS levels. The Journal of Experimental Medicine. 210: 401-16. PMID 23382545 DOI: 10.1084/jem.20121368  0.079
1983 Schofield L, Saul A, Myler P, Kidson C. Antigenic differences among isolates of Plasmodium falciparum demonstrated by monoclonal antibodies. Infection and Immunity. 38: 893-7. PMID 6185427 DOI: 10.1128/IAI.38.3.893-897.1982  0.069
2013 Buchko GW, Hewitt SN, Van Voorhis WC, Myler PJ. Solution structure of a putative FKBP-type peptidyl-propyl cis-trans isomerase from Giardia lamblia. Journal of Biomolecular Nmr. 57: 369-74. PMID 24293257 DOI: 10.1007/s10858-013-9797-8  0.067
1985 Myler PJ, Allen AL, Agabian N, Stuart K. Antigenic variation in clones of Trypanosoma brucei grown in immune-deficient mice. Infection and Immunity. 47: 684-90. PMID 2579027  0.067
1982 Myler P, Saul A, Mangan T, Kidson C. An automated assay of merozoite invasion of erythrocytes using highly synchronized Plasmodium falciparum cultures. The Australian Journal of Experimental Biology and Medical Science. 60: 83-9. PMID 7046717 DOI: 10.1038/ICB.1982.6  0.064
2011 Buchko GW, Kim H, Myler PJ, Terwilliger TC, Kim CY. Chemical shift assignments for Rv0577, a putative glyoxylase associated with virulence from Mycobacterium tuberculosis. Biomolecular Nmr Assignments. 6: 43-6. PMID 21761124 DOI: 10.1007/s12104-011-9322-5  0.059
2015 Goshu GM, Ghose D, Bain JM, Pierce PG, Begley DW, Hewitt SN, Udell HS, Myler PJ, Meganathan R, Hagen TJ. Synthesis and biological evaluation of pyrazolopyrimidines as potential antibacterial agents. Bioorganic & Medicinal Chemistry Letters. PMID 26584881 DOI: 10.1016/J.Bmcl.2015.10.096  0.053
2013 Wangtrakuldee P, Byrd MS, Campos CG, Henderson MW, Zhang Z, Clare M, Masoudi A, Myler PJ, Horn JR, Cotter PA, Hagen TJ. Discovery of Inhibitors of Burkholderia pseudomallei Methionine Aminopeptidase with Antibacterial Activity. Acs Medicinal Chemistry Letters. 4. PMID 24376907 DOI: 10.1021/Ml400034M  0.05
1982 Saul A, Myler P, Mangan T, Kidson C. Plasmodium falciparum: automated assay of erythrocyte invasion using flow cytofluorometry. Experimental Parasitology. 54: 64-71. PMID 6807707 DOI: 10.1016/0014-4894(82)90111-4  0.049
2021 Riboldi GP, Zigweid R, Myler PJ, Mayclin SJ, Couñago RM, Staker BL. Identification of P218 as a potent inhibitor of Mycobacterium ulcerans DHFR Rsc Medicinal Chemistry. 12: 103-109. DOI: 10.1039/d0md00303d  0.025
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