| Year |
Citation |
Score |
| 2023 |
Jorch SK, McNally A, Berger P, Wolf J, Kaiser K, Chetrusca Covash A, Robeck S, Pastau I, Fehler O, Jauch-Speer SL, Hermann S, Schäfers M, Van Gorp H, Kanneganti A, Dehoorne J, ... ... Chae JJ, et al. Complex regulation of alarmins S100A8/A9 and secretion via Gasdermin-D pores exacerbates autoinflammation in Familial Mediterranean Fever. The Journal of Allergy and Clinical Immunology. PMID 36822481 DOI: 10.1016/j.jaci.2023.01.037 |
0.381 |
|
| 2022 |
Magnotti F, Chirita D, Dalmon S, Martin A, Bronnec P, Sousa J, Helynck O, Lee W, Kastner DL, Chae JJ, McDermott MF, Belot A, Popoff M, Sève P, Georgin-Lavialle S, et al. Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism. Cell Reports. 41: 111472. PMID 36223753 DOI: 10.1016/j.celrep.2022.111472 |
0.31 |
|
| 2021 |
Stone DL, Ombrello A, Arostegui JI, Schneider C, Dang V, de Jesus A, Girard-Guyonvarc'h C, Gabay C, Lee W, Chae JJ, Aksentijevich I, Goldbach-Mansky RT, Kastner DL, Canna SW. Excess Serum Interleukin-18 Distinguishes Patients with Pathogenic Mutations in PSTPIP1. Arthritis & Rheumatology (Hoboken, N.J.). PMID 34492165 DOI: 10.1002/art.41976 |
0.482 |
|
| 2020 |
Park YH, Remmers EF, Lee W, Ombrello AK, Chung LK, Shilei Z, Stone DL, Ivanov MI, Loeven NA, Barron KS, Hoffmann P, Nehrebecky M, Akkaya-Ulum YZ, Sag E, Balci-Peynircioglu B, ... ... Chae JJ, et al. Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis. Nature Immunology. PMID 32601469 DOI: 10.1038/S41590-020-0705-6 |
0.366 |
|
| 2019 |
Lalaoui N, Boyden SE, Oda H, Wood GM, Stone DL, Chau D, Liu L, Stoffels M, Kratina T, Lawlor KE, Zaal KJM, Hoffmann PM, Etemadi N, Shield-Artin K, Biben C, ... ... Chae JJ, et al. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease. Nature. PMID 31827281 DOI: 10.1038/S41586-019-1828-5 |
0.318 |
|
| 2019 |
Schnappauf O, Chae JJ, Kastner DL, Aksentijevich I. The Pyrin Inflammasome in Health and Disease. Frontiers in Immunology. 10: 1745. PMID 31456795 DOI: 10.3389/fimmu.2019.01745 |
0.326 |
|
| 2017 |
Nakanishi H, Kawashima Y, Kurima K, Chae JJ, Ross AM, Pinto-Patarroyo G, Patel SK, Muskett JA, Ratay JS, Chattaraj P, Park YH, Grevich S, Brewer CC, Hoa M, Kim HJ, et al. NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847925 DOI: 10.1073/Pnas.1702946114 |
0.44 |
|
| 2016 |
Park YH, Wood G, Kastner DL, Chae JJ. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nature Immunology. PMID 27270401 DOI: 10.1038/ni.3457 |
0.465 |
|
| 2016 |
Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, et al. Control of the innate immune response by the mevalonate pathway. Nature Immunology. PMID 27270400 DOI: 10.1038/Ni.3487 |
0.303 |
|
| 2015 |
Aflaki E, Moaven N, Borger DK, Lopez G, Westbroek W, Chae JJ, Marugan J, Patnaik S, Maniwang E, Gonzalez AN, Sidransky E. Lysosomal storage and impaired autophagy lead to inflammasome activation in Gaucher macrophages. Aging Cell. PMID 26486234 DOI: 10.1111/acel.12409 |
0.617 |
|
| 2015 |
Kim ML, Chae JJ, Park YH, De Nardo D, Stirzaker RA, Ko HJ, Tye H, Cengia L, DiRago L, Metcalf D, Roberts AW, Kastner DL, Lew AM, Lyras D, Kile BT, et al. Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β. The Journal of Experimental Medicine. 212: 927-38. PMID 26008898 DOI: 10.1084/Jem.20142384 |
0.712 |
|
| 2015 |
Sokolowska M, Chen LY, Liu Y, Martinez-Anton A, Qi HY, Logun C, Alsaaty S, Park YH, Kastner DL, Chae JJ, Shelhamer JH. Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages. Journal of Immunology (Baltimore, Md. : 1950). 194: 5472-87. PMID 25917098 DOI: 10.4049/jimmunol.1401343 |
0.351 |
|
| 2012 |
Lee GS, Subramanian N, Kim AI, Aksentijevich I, Goldbach-Mansky R, Sacks DB, Germain RN, Kastner DL, Chae JJ. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature. 492: 123-7. PMID 23143333 DOI: 10.1038/Nature11588 |
0.363 |
|
| 2011 |
Chae JJ, Cho Y, Lee G, Cheng J, Liu PP, Feigenbaum L, Katz SI, Kastner DL. Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice Immunity. 34: 755-768. PMID 21600797 DOI: 10.1016/J.Immuni.2011.02.020 |
0.474 |
|
| 2010 |
Simon A, Park H, Maddipati R, Lobito AA, Bulua AC, Jackson AJ, Chae JJ, Ettinger R, de Koning HD, Cruz AC, Kastner DL, Komarow H, Siegel RM. Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome. Proceedings of the National Academy of Sciences of the United States of America. 107: 9801-6. PMID 20457915 DOI: 10.1073/Pnas.0914118107 |
0.313 |
|
| 2006 |
Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL. The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. Proceedings of the National Academy of Sciences of the United States of America. 103: 9982-7. PMID 16785446 DOI: 10.1073/pnas.0602081103 |
0.405 |
|
| 2003 |
Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Molecular Cell. 11: 591-604. PMID 12667444 DOI: 10.1016/S1097-2765(03)00056-X |
0.517 |
|
| 2002 |
Aksentijevich I, Nowak M, Mallah M, Chae JJ, Watford WT, Hofmann SR, Stein L, Russo R, Goldsmith D, Dent P, Rosenberg HF, Austin F, Remmers EF, Balow JE, Rosenzweig S, et al. De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis and Rheumatism. 46: 3340-8. PMID 12483741 DOI: 10.1002/Art.10688 |
0.439 |
|
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