John Biggins
Affiliations: | 2003-2009 | Chemistry and Biochemistry | LifeMine Therapeutics |
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Parents
Sign in to add mentor| Jon S. Thorson | grad student | 1997-2004 | Sloan Kettering Institute |
| John T. Koh | post-doc | 2004-2009 | U Delaware |
| Sean F. Brady | post-doc | 2010-2016 | Rockefeller |
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Publications
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| Peek J, Lilic M, Montiel D, et al. (2018) Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nature Communications. 9: 4147 |
| Medema MH, Kottmann R, Yilmaz P, et al. (2015) Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31 |
| Biggins JB, Kang HS, Ternei MA, et al. (2014) The chemical arsenal of Burkholderia pseudomallei is essential for pathogenicity. Journal of the American Chemical Society. 136: 9484-90 |
| Biggins JB, Kang HS, Ternei MA, et al. (2014) The chemical arsenal of burkholderia pseudomallei is essential for pathogenicity Journal of the American Chemical Society. 136: 9484-9490 |
| Biggins JB, Ternei MA, Brady SF. (2012) Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens. Journal of the American Chemical Society. 134: 13192-5 |
| Biggins JB, Gleber CD, Brady SF. (2011) Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis. Organic Letters. 13: 1536-9 |
| Biggins JB, Liu X, Feng Z, et al. (2011) Metabolites from the induced expression of cryptic single operons found in the genome of Burkholderia pseudomallei. Journal of the American Chemical Society. 133: 1638-41 |
| Sauers DJ, Temburni MK, Biggins JB, et al. (2010) Light-activated gene expression directs segregation of co-cultured cells in vitro. Acs Chemical Biology. 5: 313-20 |
| Biggins JB, Hashimoto A, Koh JT. (2007) Photocaged agonist for an analogue-specific form of the vitamin D receptor. Chembiochem : a European Journal of Chemical Biology. 8: 799-803 |
| Biggins JB, Koh JT. (2007) Chemical biology of steroid and nuclear hormone receptors. Current Opinion in Chemical Biology. 11: 99-110 |