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Paul Wentworth - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Biochemistry, Immunology
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Cygan NK, Scheinost JC, Butters TD, Wentworth P. Adduction of cholesterol 5,6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope. Biochemistry. 50: 2092-100. PMID 21314187 DOI: 10.1021/Bi200109Q  0.312
2008 Wentworth P, Witter DP. Antibody-catalyzed water-oxidation pathway Pure and Applied Chemistry. 80: 1849-1858. DOI: 10.1351/Pac200880081849  0.357
2007 Xu Y, Hixon MS, Yamamoto N, McAllister LA, Wentworth AD, Wentworth P, Janda KD. Antibody-catalyzed anaerobic destruction of methamphetamine. Proceedings of the National Academy of Sciences of the United States of America. 104: 3681-6. PMID 17360412 DOI: 10.1073/Pnas.0611094104  0.365
2006 Zhu X, Wentworth P, Kyle RA, Lerner RA, Wilson IA. Cofactor-containing antibodies: crystal structure of the original yellow antibody. Proceedings of the National Academy of Sciences of the United States of America. 103: 3581-5. PMID 16537445 DOI: 10.1073/Pnas.0600251103  0.361
2006 Nieva J, Kerwin L, Wentworth AD, Lerner RA, Wentworth P. Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway. Immunology Letters. 103: 33-8. PMID 16386801 DOI: 10.1016/J.Imlet.2005.11.020  0.355
2004 Nieva J, Wentworth P. The antibody-catalyzed water oxidation pathway--a new chemical arm to immune defense? Trends in Biochemical Sciences. 29: 274-8. PMID 15130564 DOI: 10.1016/J.Tibs.2004.03.009  0.347
2004 Zhu X, Wentworth P, Wentworth AD, Eschenmoser A, Lerner RA, Wilson IA. Probing the antibody-catalyzed water-oxidation pathway at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 101: 2247-52. PMID 14982995 DOI: 10.1073/Pnas.0307311101  0.355
2004 Muranova TA, Ruzheinikov SN, Higginbottom A, Clipson JA, Blackburn GM, Wentworth P, Datta A, Rice DW, Partridge LJ. Crystallization of a carbamatase catalytic antibody Fab fragment and its complex with a transition-state analogue. Acta Crystallographica. Section D, Biological Crystallography. 60: 172-4. PMID 14684920 DOI: 10.1107/S0907444903026350  0.322
2003 Ahn JM, Wentworth P, Janda KD. Soluble polymer-supported convergent parallel library synthesis. Chemical Communications (Cambridge, England). 480-1. PMID 12638959 DOI: 10.1039/B210696E  0.314
2003 Babior BM, Takeuchi C, Ruedi J, Gutierrez A, Wentworth P. Investigating antibody-catalyzed ozone generation by human neutrophils. Proceedings of the National Academy of Sciences of the United States of America. 100: 3031-4. PMID 12601145 DOI: 10.1073/Pnas.0530251100  0.323
2003 Wentworth P, Wentworth AD, Zhu X, Wilson IA, Janda KD, Eschenmoser A, Lerner RA. Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens. Proceedings of the National Academy of Sciences of the United States of America. 100: 1490-3. PMID 12576548 DOI: 10.1073/Pnas.0437831100  0.373
2002 Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschenmoser A, Lerner RA. Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science (New York, N.Y.). 298: 2195-9. PMID 12434011 DOI: 10.1126/Science.1077642  0.37
2002 Wentworth P. Tech.Sight. Antibody design by man and nature. Science (New York, N.Y.). 296: 2247-9. PMID 12077422 DOI: 10.1126/Science.296.5576.2247  0.379
2002 Delgado M, Lee KJ, Altobell L, Spanka C, Wentworth P, Janda KD. A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity. Journal of the American Chemical Society. 124: 4946-7. PMID 11982344 DOI: 10.1021/Ja025715B  0.339
2002 Wentworth P, Janda KD. Catalytic antibodies: structure and function. Cell Biochemistry and Biophysics. 35: 63-87. PMID 11898856 DOI: 10.1385/Cbb:35:1:63  0.352
2002 Nicholas KM, Wentworth P, Harwig CW, Wentworth AD, Shafton A, Janda KD. A cofactor approach to copper-dependent catalytic antibodies. Proceedings of the National Academy of Sciences of the United States of America. 99: 2648-53. PMID 11880619 DOI: 10.1073/Pnas.052001099  0.308
2001 Wentworth P, Jones LH, Wentworth AD, Zhu X, Larsen NA, Wilson IA, Xu X, Goddard WA, Janda KD, Eschenmoser A, Lerner RA. Antibody catalysis of the oxidation of water. Science (New York, N.Y.). 293: 1806-11. PMID 11546867 DOI: 10.1126/Science.1062722  0.342
2001 Jones LH, Harwig CW, Wentworth P, Simeonov A, Wentworth AD, Py S, Ashley JA, Lerner RA, Janda KD. Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: implications for an alternative enediyne therapeutic mechanism. Journal of the American Chemical Society. 123: 3607-8. PMID 11472138 DOI: 10.1021/Ja005864Z  0.35
2001 López-Pelegrín JA, Wentworth P, Sieber F, Metz WA, Janda KD. Soluble polymer-supported chemoenzymatic synthesis of the C(21)-C(27) fragment of the bryostatins. The Journal of Organic Chemistry. 65: 8527-31. PMID 11112572 DOI: 10.1021/Jo005539U  0.314
2000 Tremblay MR, Wentworth P, Lee GE, Janda KD. Parallel solid-phase synthesis and structural characterization of a library of highly substituted chiral 1,3-oxazolidines. Journal of Combinatorial Chemistry. 2: 698-709. PMID 11126298 DOI: 10.1021/Cc0000500  0.301
2000 Wentworth AD, Jones LH, Wentworth P, Janda KD, Lerner RA. Antibodies have the intrinsic capacity to destroy antigens. Proceedings of the National Academy of Sciences of the United States of America. 97: 10930-5. PMID 11005865 DOI: 10.1073/Pnas.97.20.10930  0.35
2000 Sieber F, Wentworth P, Janda K. Exploiting Poly(ethylene glycol) as a Matrix for Liquid-Phase Organic Synthesis Molecules. 5: 1018-1032. DOI: 10.3390/50801018  0.331
1999 Wentworth P. Recent developments and applications of liquid-phase strategies in organic synthesis. Trends in Biotechnology. 17: 448-452. PMID 10511703 DOI: 10.1016/S0167-7799(99)01374-8  0.304
1999 Wentworth P, Janda KD. Antibody catalysis of phosphodiester hydrolysis a survey of hapten strategies Phosphorus Sulfur and Silicon and the Related Elements. 144: 247-250. DOI: 10.1080/10426509908039543  0.347
1999 Sieber F, Wentworth P, Toker JD, Wentworth AD, Metz WA, Reed NN, Janda KD. Development and application of a poly(ethylene glycol)-supported triarylphosphine reagent: Expanding the sphere of liquid-phase organic synthesis Journal of Organic Chemistry. 64: 5188-5192. DOI: 10.1021/Jo9903712  0.325
1999 Brümmer O, Wentworth P, Weiner DP, Janda KD. Phosphorodithioates: synthesis and evaluation of new haptens for the generation of antibody acyl transferases Tetrahedron Letters. 40: 7307-7310. DOI: 10.1016/S0040-4039(99)01501-4  0.339
1998 Wentworth P, Liu Y, Wentworth AD, Fan P, Foley MJ, Janda KD. A bait and switch hapten strategy generates catalytic antibodies for phosphodiester hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 95: 5971-5. PMID 9600901 DOI: 10.1073/Pnas.95.11.5971  0.364
1998 Gao C, Lavey BJ, Lo CL, Datta A, Wentworth P, Janda KD. Direct Selection for Catalysis from Combinatorial Antibody Libraries Using a Boronic Acid Probe:  Primary Amide Bond Hydrolysis Journal of the American Chemical Society. 120: 2211-2217. DOI: 10.1021/Ja9720220  0.349
1997 Wentworth P, Datta A, Smith S, Marshall A, Partridge LJ, Blackburn GM. Antibody Catalysis of BAc2 Aryl Carbamate Ester Hydrolysis:  A Highly Disfavored Chemical Process.  J.Am.Chem.Soc.1997,119, 2315−2316 Journal of the American Chemical Society. 119: 5275-5275. DOI: 10.1021/Ja975404E  0.342
1997 Lo CL, Wentworth P, Jung KW, Yoon J, Ashley JA, Janda KD. Reactive Immunization Strategy Generates Antibodies with High Catalytic Proficiencies Journal of the American Chemical Society. 119: 10251-10252. DOI: 10.1021/Ja971442M  0.334
1997 Wentworth P, Datta A, Smith S, Marshall A, Partridge LJ, Blackburn GM. Antibody Catalysis of BAc2 Aryl Carbamate Ester Hydrolysis:  A Highly Disfavored Chemical Process Journal of the American Chemical Society. 119: 2315-2316. DOI: 10.1021/Ja961625T  0.359
1996 Wentworth P, Datta A, Blakey D, Boyle T, Partridge LJ, Blackburn GM. Toward antibody-directed "abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing. Proceedings of the National Academy of Sciences of the United States of America. 93: 799-803. PMID 8570638 DOI: 10.1073/Pnas.93.2.799  0.352
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