Year |
Citation |
Score |
2023 |
Boyd AL, Lu J, Hollands CG, Alsostovar L, Murali S, Reid JC, Ye W, Vandersluis S, Johnson P, ElRafie A, Porras DP, Xenocostas D, Leber A, Leber B, Foley R, ... ... Bhatia M, et al. Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia. Cell Reports. Medicine. 101108. PMID 37433297 DOI: 10.1016/j.xcrm.2023.101108 |
0.338 |
|
2023 |
Golubeva D, Porras DP, Doyle M, Reid JC, Tanasijevic B, Boyd AL, Vojnits K, Elrafie A, Qiao A, Bhatia M. Reprogramming of Acute Myeloid Leukemia Patients Cells: Harboring Cancer Mutations Requires Targeting of AML Hierarchy. Stem Cells Translational Medicine. PMID 37226319 DOI: 10.1093/stcltm/szad022 |
0.429 |
|
2022 |
Porras DP, Reid JC, Tanasijevic B, Golubeva D, Boyd AL, Bhatia M. Challenges in Cell Fate Acquisition to Scid-Repopulating Activity from Hemogenic Endothelium of hiPSCs Derived from AML Patients Using Forced Transcription Factor Expression. Cells. 11. PMID 35741044 DOI: 10.3390/cells11121915 |
0.496 |
|
2022 |
Bhatia M, Elrafie A. Biting into a union of oncology and metabolism through leukemic stem cells. Cell Metabolism. 34: 801-802. PMID 35675797 DOI: 10.1016/j.cmet.2022.05.006 |
0.402 |
|
2021 |
Benoit YD, Mitchell RR, Wang W, Orlando L, Boyd AL, Tanasijevic B, Aslostovar L, Shapovalova Z, Doyle M, Bergin CJ, Vojnits K, Casado FL, Di Lu J, Porras DP, García-Rodriguez JL, ... ... Bhatia M, et al. Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics. Cell Chemical Biology. PMID 33979648 DOI: 10.1016/j.chembiol.2021.04.014 |
0.401 |
|
2021 |
Reid JC, Golubeva D, Boyd AL, Hollands CG, Henly C, Orlando L, Leber A, Hébert J, Morabito F, Cutrona G, Agnelli L, Gentile M, Ferrarini M, Neri A, Leber B, ... Bhatia M, et al. Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients. Cell Reports. 34: 108845. PMID 33730576 DOI: 10.1016/j.celrep.2021.108845 |
0.339 |
|
2021 |
Orlando L, Tanasijevic B, Nakanishi M, Reid JC, García-Rodríguez JL, Chauhan KD, Porras DP, Aslostovar L, Lu JD, Shapovalova Z, Mitchell RR, Boyd AL, Bhatia M. Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions. Cell Reports. 34: 108818. PMID 33691101 DOI: 10.1016/j.celrep.2021.108818 |
0.404 |
|
2019 |
Vojnits K, Mahammad S, Collins TJ, Bhatia M. Chemotherapy-Induced Neuropathy and Drug Discovery Platform Using Human Sensory Neurons Converted Directly from Adult Peripheral Blood. Stem Cells Translational Medicine. PMID 31347791 DOI: 10.1002/Sctm.19-0054 |
0.383 |
|
2019 |
Nakanishi M, Mitchell RR, Benoit YD, Orlando L, Reid JC, Shimada K, Davidson KC, Shapovalova Z, Collins TJ, Nagy A, Bhatia M. Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells. Cell. PMID 30982595 DOI: 10.1016/J.Cell.2019.03.013 |
0.581 |
|
2018 |
Boyd AL, Aslostovar L, Reid J, Ye W, Tanasijevic B, Porras DP, Shapovalova Z, Almakadi M, Foley R, Leber B, Xenocostas A, Bhatia M. Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence. Cancer Cell. 34: 483-498.e5. PMID 30205048 DOI: 10.1016/J.Ccell.2018.08.007 |
0.438 |
|
2018 |
Reid JC, Tanasijevic B, Golubeva D, Boyd AL, Porras DP, Collins TJ, Bhatia M. CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure. Stem Cell Reports. 10: 1625-1641. PMID 29742393 DOI: 10.1016/J.Stemcr.2018.04.003 |
0.559 |
|
2017 |
Boyd AL, Reid JC, Salci KR, Aslostovar L, Benoit YD, Shapovalova Z, Nakanishi M, Porras DP, Almakadi M, Campbell CJV, Jackson MF, Ross CA, Foley R, Leber B, Allan DS, ... ... Bhatia M, et al. Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche. Nature Cell Biology. PMID 29035359 DOI: 10.1038/Ncb3625 |
0.481 |
|
2017 |
Lee JH, Salci KR, Reid JC, Orlando L, Tanasijevic B, Shapovalova Z, Bhatia M. Brief Report: Human Acute Myeloid Leukemia Reprograming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations. Stem Cells (Dayton, Ohio). PMID 28758276 DOI: 10.1002/Stem.2655 |
0.516 |
|
2017 |
Benoit YD, Mitchell RR, Risueño RM, Orlando L, Tanasijevic B, Boyd AL, Aslostovar L, Salci KR, Shapovalova Z, Russell J, Eguchi M, Golubeva D, Graham M, Xenocostas A, Trus MR, ... ... Bhatia M, et al. Sam68 Allows Selective Targeting of Human Cancer Stem Cells. Cell Chemical Biology. PMID 28648376 DOI: 10.1016/J.Chembiol.2017.05.026 |
0.486 |
|
2017 |
Lee JH, Laronde S, Collins TJ, Shapovalova Z, Tanasijevic B, McNicol JD, Fiebig-Comyn A, Benoit YD, Lee JB, Mitchell RR, Bhatia M. Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency. Cell Reports. 19: 20-35. PMID 28380358 DOI: 10.1016/J.Celrep.2017.03.036 |
0.533 |
|
2016 |
Guezguez B, Almakadi M, Benoit YD, Shapovalova Z, Rahmig S, Fiebig-Comyn A, Casado FL, Tanasijevic B, Bresolin S, Masetti R, Doble BW, Bhatia M. GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia. Cancer Cell. 29: 61-74. PMID 26766591 DOI: 10.1016/J.Ccell.2015.11.012 |
0.362 |
|
2015 |
Boyd AL, Bhatia M. Playing musical chairs with bone marrow transplantation to eliminate leukemia stem cells. Molecular & Cellular Oncology. 2: e988480. PMID 27308468 DOI: 10.4161/23723556.2014.988480 |
0.492 |
|
2015 |
Singh SK, Venugopal C, Hallett R, Vora P, Manoranjan B, Mahendram S, Qazi M, McFarlane N, Subapanditha M, Nolte S, Singh M, Bakhshinyan D, Garg N, Vijayakumar T, Lach B, ... ... Bhatia M, et al. Pyrvinium targets CD133 in human glioblastoma brain tumor-initiating cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26152745 DOI: 10.1158/1078-0432.Ccr-14-3147 |
0.475 |
|
2015 |
Salci KR, Lee JB, Mitchell RR, Orlando L, Fiebig-Comyn A, Shapovalova Z, Bhatia M. Derivation of human induced pluripotent stem cells through continued exposure of OCT4-induced plastic human fibroblasts to reprogramming media. Stem Cell Research. 15: 240-242. PMID 26141785 DOI: 10.1016/J.Scr.2015.06.005 |
0.504 |
|
2015 |
Salci KR, Lee JB, Mitchell RR, Orlando L, Fiebig-Comyn A, Shapovalova Z, Bhatia M. Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts. Stem Cell Research. 15: 221-230. PMID 26117529 DOI: 10.1016/J.Scr.2015.06.006 |
0.548 |
|
2015 |
Lee JH, Mitchell RR, McNicol JD, Shapovalova Z, Laronde S, Tanasijevic B, Milsom C, Casado F, Fiebig-Comyn A, Collins TJ, Singh KK, Bhatia M. Single Transcription Factor Conversion of Human Blood Fate to NPCs with CNS and PNS Developmental Capacity. Cell Reports. 11: 1367-76. PMID 26004181 DOI: 10.1016/J.Celrep.2015.04.056 |
0.431 |
|
2015 |
Salci KR, Lee JH, Laronde S, Dingwall S, Kushwah R, Fiebig-Comyn A, Leber B, Foley R, Dal Cin A, Bhatia M. Cellular Reprogramming Allows Generation of Autologous Hematopoietic Progenitors From AML Patients That Are Devoid of Patient-Specific Genomic Aberrations. Stem Cells (Dayton, Ohio). 33: 1839-49. PMID 25764124 DOI: 10.1002/Stem.1994 |
0.497 |
|
2015 |
Lee JB, Graham M, Collins TJ, Lee JH, Hong SH, Mcnicol AJ, Shapovalova Z, Bhatia M. Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. Stem Cells (Dayton, Ohio). 33: 1142-52. PMID 25639500 DOI: 10.1002/Stem.1952 |
0.605 |
|
2015 |
McIntyre BA, Kushwah R, Mechael R, Shapovalova Z, Alev C, Bhatia M. Innate immune response of human pluripotent stem cell-derived airway epithelium. Innate Immunity. 21: 504-11. PMID 25261966 DOI: 10.1177/1753425914551074 |
0.47 |
|
2015 |
Venugopal C, Hallett R, Vora P, Manoranjan B, Mahendram S, Qazi M, McFarlane N, Subapanditha M, Nolte S, Singh M, Bakhshinyan D, Garg N, Boleslaw L, John P, Reddy K, ... ... Bhatia M, et al. STEM-23PYRVINIUM TARGETS CD133 IN HUMAN GLIOBLASTOMA BRAIN TUMOR-INITIATING CELLS Neuro-Oncology. 17: v213.1-v213. DOI: 10.1093/Neuonc/Nov234.23 |
0.466 |
|
2014 |
Lee JH, Lee JB, Shapovalova Z, Fiebig-Comyn A, Mitchell RR, Laronde S, Szabo E, Benoit YD, Bhatia M. Somatic transcriptome priming gates lineage-specific differentiation potential of human-induced pluripotent stem cell states. Nature Communications. 5: 5605. PMID 25465724 DOI: 10.1038/Ncomms6605 |
0.565 |
|
2014 |
Kushwah R, Guezguez B, Lee JB, Hopkins CI, Bhatia M. Pleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human. Embo Reports. 15: 1128-38. PMID 25252682 DOI: 10.15252/Embr.201438842 |
0.488 |
|
2014 |
Boyd AL, Campbell CJ, Hopkins CI, Fiebig-Comyn A, Russell J, Ulemek J, Foley R, Leber B, Xenocostas A, Collins TJ, Bhatia M. Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs. The Journal of Experimental Medicine. 211: 1925-35. PMID 25180064 DOI: 10.1084/Jem.20140131 |
0.557 |
|
2014 |
Benoit YD, Guezguez B, Boyd AL, Bhatia M. Molecular pathways: epigenetic modulation of Wnt-glycogen synthase kinase-3 signaling to target human cancer stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5372-8. PMID 25006223 DOI: 10.1158/1078-0432.Ccr-13-2491 |
0.446 |
|
2014 |
Boyd AL, Bhatia M. Bone marrow localization and functional properties of human hematopoietic stem cells. Current Opinion in Hematology. 21: 249-55. PMID 24848771 DOI: 10.1097/Moh.0000000000000055 |
0.538 |
|
2014 |
Guezguez B, Bhatia M. Driving human-mouse avatars to understand the HSC niche. Cell Cycle (Georgetown, Tex.). 13: 1511-2. PMID 24755946 DOI: 10.4161/Cc.28958 |
0.58 |
|
2014 |
Mitchell R, Szabo E, Shapovalova Z, Aslostovar L, Makondo K, Bhatia M. Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors. Stem Cells (Dayton, Ohio). 32: 2178-87. PMID 24740884 DOI: 10.1002/Stem.1721 |
0.553 |
|
2014 |
Mitchell RR, Szabo E, Benoit YD, Case DT, Mechael R, Alamilla J, Lee JH, Fiebig-Comyn A, Gillespie DC, Bhatia M. Activation of neural cell fate programs toward direct conversion of adult human fibroblasts into tri-potent neural progenitors using OCT-4. Stem Cells and Development. 23: 1937-46. PMID 24694094 DOI: 10.1089/Scd.2014.0023 |
0.455 |
|
2014 |
McIntyre BA, Alev C, Mechael R, Salci KR, Lee JB, Fiebig-Comyn A, Guezguez B, Wu Y, Sheng G, Bhatia M. Expansive generation of functional airway epithelium from human embryonic stem cells. Stem Cells Translational Medicine. 3: 7-17. PMID 24300555 DOI: 10.5966/Sctm.2013-0119 |
0.468 |
|
2013 |
Guezguez B, Campbell CJ, Boyd AL, Karanu F, Casado FL, Di Cresce C, Collins TJ, Shapovalova Z, Xenocostas A, Bhatia M. Regional localization within the bone marrow influences the functional capacity of human HSCs. Cell Stem Cell. 13: 175-89. PMID 23910084 DOI: 10.1016/J.Stem.2013.06.015 |
0.428 |
|
2013 |
Schnerch A, Rampalii S, Bhatia M. Histone modification profiling in normal and transformed human embryonic stem cells using micro chromatin immunoprecipitation, scalable to genome-wide microarray analyses. Methods in Molecular Biology (Clifton, N.J.). 1029: 149-61. PMID 23756948 DOI: 10.1007/978-1-62703-478-4_11 |
0.537 |
|
2013 |
Boyd AL, Salci KR, Shapovalova Z, McIntyre BA, Bhatia M. Nonhematopoietic cells represent a more rational target of in vivo hedgehog signaling affecting normal or acute myeloid leukemia progenitors. Experimental Hematology. 41: 858-869.e4. PMID 23747997 DOI: 10.1016/J.Exphem.2013.05.287 |
0.539 |
|
2013 |
Lee JB, Werbowetski-Ogilvie TE, Lee JH, McIntyre BA, Schnerch A, Hong SH, Park IH, Daley GQ, Bernstein ID, Bhatia M. Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells. Blood. 122: 1162-73. PMID 23733337 DOI: 10.1182/Blood-2012-12-471649 |
0.512 |
|
2013 |
Salci KR, McIntyre BA, Bhatia M. Foundational concepts of cell fate conversion to the hematopoietic lineage. Current Opinion in Genetics & Development. 23: 585-90. PMID 23725798 DOI: 10.1016/J.Gde.2013.04.007 |
0.564 |
|
2013 |
McIntyre BA, Ramos-Mejia V, Rampalli S, Mechael R, Lee JH, Alev C, Sheng G, Bhatia M. Gli3-mediated hedgehog inhibition in human pluripotent stem cells initiates and augments developmental programming of adult hematopoiesis. Blood. 121: 1543-52. PMID 23293081 DOI: 10.1182/Blood-2012-09-457747 |
0.5 |
|
2013 |
Schnerch A, Lee JB, Graham M, Guezguez B, Bhatia M. Human embryonic stem cell-derived hematopoietic cells maintain core epigenetic machinery of the polycomb group/Trithorax Group complexes distinctly from functional adult hematopoietic stem cells. Stem Cells and Development. 22: 73-89. PMID 22800282 DOI: 10.1089/Scd.2012.0204 |
0.64 |
|
2013 |
Ji J, Zhong B, Bhatia M. Genetic Approaches in Human Embryonic Stem Cells and their Derivatives. Prospects for Regenerative Medicine Handbook of Stem Cells. 1: 311-325. DOI: 10.1016/B978-0-12-385942-6.00025-1 |
0.46 |
|
2012 |
Oh SW, Lee JB, Kim B, Jeon S, Kim MK, Nam KH, Ha JR, Bhatia M, Oh GT, Kim DY. Peptidomimetic small-molecule compounds promoting cardiogenesis of stem cells. Archives of Pharmacal Research. 35: 1979-88. PMID 23212640 DOI: 10.1007/S12272-012-1115-6 |
0.577 |
|
2012 |
Rampalli S, Bhatia M. Human pluripotency: a difficult state to make smart choices. Cell Cycle (Georgetown, Tex.). 11: 2411-2. PMID 22713241 DOI: 10.4161/Cc.20801 |
0.611 |
|
2012 |
Sachlos E, Risueño RM, Laronde S, Shapovalova Z, Lee JH, Russell J, Malig M, McNicol JD, Fiebig-Comyn A, Graham M, Levadoux-Martin M, Lee JB, Giacomelli AO, Hassell JA, Fischer-Russell D, ... ... Bhatia M, et al. Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell. 149: 1284-97. PMID 22632761 DOI: 10.1016/J.Cell.2012.03.049 |
0.504 |
|
2012 |
Cerdan C, McIntyre BA, Mechael R, Levadoux-Martin M, Yang J, Lee JB, Bhatia M. Activin A promotes hematopoietic fated mesoderm development through upregulation of brachyury in human embryonic stem cells. Stem Cells and Development. 21: 2866-77. PMID 22548442 DOI: 10.1089/Scd.2012.0053 |
0.606 |
|
2012 |
Werbowetski-Ogilvie TE, Morrison LC, Fiebig-Comyn A, Bhatia M. In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation. Stem Cells (Dayton, Ohio). 30: 392-404. PMID 22213600 DOI: 10.1002/Stem.1017 |
0.478 |
|
2012 |
Risueño RM, Sachlos E, Lee JH, Lee JB, Hong SH, Szabo E, Bhatia M. Inability of human induced pluripotent stem cell-hematopoietic derivatives to downregulate microRNAs in vivo reveals a block in xenograft hematopoietic regeneration. Stem Cells (Dayton, Ohio). 30: 131-9. PMID 22131151 DOI: 10.1002/Stem.1684 |
0.599 |
|
2011 |
Hong SH, Rampalli S, Lee JB, McNicol J, Collins T, Draper JS, Bhatia M. Cell fate potential of human pluripotent stem cells is encoded by histone modifications. Cell Stem Cell. 9: 24-36. PMID 21726831 DOI: 10.1016/J.Stem.2011.06.002 |
0.635 |
|
2011 |
Risueño RM, Campbell CJ, Dingwall S, Levadoux-Martin M, Leber B, Xenocostas A, Bhatia M. Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease. Blood. 117: 7112-20. PMID 21562049 DOI: 10.1182/Blood-2011-01-329078 |
0.462 |
|
2011 |
Ellis J, Bhatia M. iPSC technology: platform for drug discovery. Point. Clinical Pharmacology and Therapeutics. 89: 639-41. PMID 21512521 DOI: 10.1038/Clpt.2011.22 |
0.515 |
|
2011 |
Hong SH, Lee JH, Lee JB, Ji J, Bhatia M. ID1 and ID3 represent conserved negative regulators of human embryonic and induced pluripotent stem cell hematopoiesis. Journal of Cell Science. 124: 1445-52. PMID 21486943 DOI: 10.1242/Dev.068304 |
0.62 |
|
2011 |
Hope K, Bhatia M. Clonal interrogation of stem cells. Nature Methods. 8: S36-40. PMID 21451511 DOI: 10.1038/Nmeth.1590 |
0.597 |
|
2011 |
Ji J, Risueño RM, Hong S, Allan D, Rosten P, Humphries K, Bhatia M. Brief report: ectopic expression of NUP98-HOXA10 augments erythroid differentiation of human embryonic stem cells. Stem Cells (Dayton, Ohio). 29: 736-41. PMID 21328509 DOI: 10.1002/Stem.622 |
0.616 |
|
2011 |
Ji J, Zhong B, Bhatia M. Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine Principles of Regenerative Medicine. 179-198. DOI: 10.1016/B978-0-12-381422-7.10009-4 |
0.358 |
|
2010 |
Szabo E, Rampalli S, Risueño RM, Schnerch A, Mitchell R, Fiebig-Comyn A, Levadoux-Martin M, Bhatia M. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature. 468: 521-6. PMID 21057492 DOI: 10.1038/Nature09591 |
0.64 |
|
2010 |
Stewart MH, Bendall SC, Levadoux-Martin M, Bhatia M. Clonal tracking of hESCs reveals differential contribution to functional assays. Nature Methods. 7: 917-22. PMID 20953174 DOI: 10.1038/Nmeth.1519 |
0.784 |
|
2010 |
Bhatia M. Developmental biology. Microenvironment mimicry. Science (New York, N.Y.). 329: 1024-5. PMID 20798306 DOI: 10.1126/Science.1194919 |
0.307 |
|
2010 |
Hong SH, Werbowetski-Ogilvie T, Ramos-Mejia V, Lee JB, Bhatia M. Multiparameter comparisons of embryoid body differentiation toward human stem cell applications. Stem Cell Research. 5: 120-30. PMID 20605758 DOI: 10.1016/J.Scr.2010.04.007 |
0.565 |
|
2010 |
Campbell CJ, Lee JB, Levadoux-Martin M, Wynder T, Xenocostas A, Leber B, Bhatia M. The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity. Blood. 116: 1433-42. PMID 20525924 DOI: 10.1182/Blood-2009-12-258095 |
0.617 |
|
2010 |
Trowbridge JJ, Guezguez B, Moon RT, Bhatia M. Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity. Stem Cells (Dayton, Ohio). 28: 1379-89. PMID 20521329 DOI: 10.1002/Stem.457 |
0.512 |
|
2010 |
Cerdan C, Bhatia M. Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells. The International Journal of Developmental Biology. 54: 955-63. PMID 20336604 DOI: 10.1387/Ijdb.103067Cc |
0.616 |
|
2010 |
Moogk D, Stewart M, Gamble D, Bhatia M, Jervis E. Human ESC colony formation is dependent on interplay between self-renewing hESCs and unique precursors responsible for niche generation. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 321-7. PMID 20217858 DOI: 10.1002/Cyto.A.20878 |
0.802 |
|
2010 |
Schnerch A, Cerdan C, Bhatia M. Distinguishing between mouse and human pluripotent stem cell regulation: the best laid plans of mice and men. Stem Cells (Dayton, Ohio). 28: 419-30. PMID 20054863 DOI: 10.1002/Stem.298 |
0.524 |
|
2010 |
Risueño RM, Szabo E, Dang UM, Levadoux-Martin M, Chung J, Xenocostas A, Leber B, Bhatia M. Differential Dependence On Wnt Signaling Allows Chemical Mediated Eradication of Human Acute Leukemia without Affecting Normal Blood Stem Cells Blood. 116: 3278-3278. DOI: 10.1182/Blood.V116.21.3278.3278 |
0.524 |
|
2009 |
Ji J, Werbowetski-Ogilvie TE, Zhong B, Hong SH, Bhatia M. Pluripotent transcription factors possess distinct roles in normal versus transformed human stem cells. Plos One. 4: e8065. PMID 19956629 DOI: 10.1371/Journal.Pone.0008065 |
0.513 |
|
2009 |
Bhatia M. Mickie Bhatia: Embryonic stem cells come of age. The Journal of Experimental Medicine. 206: 2056-7. PMID 19808261 DOI: 10.1084/jem.20610pi |
0.43 |
|
2009 |
Hotta A, Cheung AY, Farra N, Vijayaragavan K, Séguin CA, Draper JS, Pasceri P, Maksakova IA, Mager DL, Rossant J, Bhatia M, Ellis J. Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency. Nature Methods. 6: 370-6. PMID 19404254 DOI: 10.1038/Nmeth.1325 |
0.586 |
|
2009 |
Vijayaragavan K, Szabo E, Bossé M, Ramos-Mejia V, Moon RT, Bhatia M. Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells. Cell Stem Cell. 4: 248-62. PMID 19265664 DOI: 10.1016/J.Stem.2008.12.011 |
0.571 |
|
2009 |
Werbowetski-Ogilvie TE, Bossé M, Stewart M, Schnerch A, Ramos-Mejia V, Rouleau A, Wynder T, Smith MJ, Dingwall S, Carter T, Williams C, Harris C, Dolling J, Wynder C, Boreham D, ... Bhatia M, et al. Characterization of human embryonic stem cells with features of neoplastic progression. Nature Biotechnology. 27: 91-7. PMID 19122652 DOI: 10.1038/Nbt.1516 |
0.8 |
|
2009 |
Bendall SC, Hughes C, Campbell JL, Stewart MH, Pittock P, Liu S, Bonneil E, Thibault P, Bhatia M, Lajoie GA. An enhanced mass spectrometry approach reveals human embryonic stem cell growth factors in culture. Molecular & Cellular Proteomics : McP. 8: 421-32. PMID 18936058 DOI: 10.1074/Mcp.M800190-Mcp200 |
0.72 |
|
2008 |
Ji J, Vijayaragavan K, Bosse M, Menendez P, Weisel K, Bhatia M. OP9 stroma augments survival of hematopoietic precursors and progenitors during hematopoietic differentiation from human embryonic stem cells. Stem Cells (Dayton, Ohio). 26: 2485-95. PMID 18669904 DOI: 10.1634/Stemcells.2008-0642 |
0.642 |
|
2008 |
Guezguez B, Bhatia M. Transplantation of human hematopoietic repopulating cells: mechanisms of regeneration and differentiation using human-mouse xenografts. Current Opinion in Organ Transplantation. 13: 44-52. PMID 18660706 DOI: 10.1097/Mot.0B013E3282F42486 |
0.466 |
|
2008 |
Werbowetski-Ogilvie TE, Bhatia M. Pluripotent human stem cell lines: what we can learn about cancer initiation. Trends in Molecular Medicine. 14: 323-32. PMID 18635398 DOI: 10.1016/J.Molmed.2008.06.005 |
0.511 |
|
2008 |
Dey BK, Stalker L, Schnerch A, Bhatia M, Taylor-Papidimitriou J, Wynder C. The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation. Molecular and Cellular Biology. 28: 5312-27. PMID 18591252 DOI: 10.1128/Mcb.00128-08 |
0.525 |
|
2008 |
Campbell C, Risueno RM, Salati S, Guezguez B, Bhatia M. Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects. Current Opinion in Hematology. 15: 319-25. PMID 18536569 DOI: 10.1097/Moh.0B013E328303B9Df |
0.586 |
|
2008 |
Stewart MH, Bendall SC, Bhatia M. Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency. Journal of Molecular Medicine (Berlin, Germany). 86: 875-86. PMID 18521556 DOI: 10.1007/S00109-008-0356-9 |
0.822 |
|
2008 |
Bendall SC, Hughes C, Stewart MH, Doble B, Bhatia M, Lajoie GA. Prevention of amino acid conversion in SILAC experiments with embryonic stem cells. Molecular & Cellular Proteomics : McP. 7: 1587-97. PMID 18487603 DOI: 10.1074/Mcp.M800113-Mcp200 |
0.756 |
|
2008 |
Bendall SC, Stewart MH, Bhatia M. Human embryonic stem cells: lessons from stem cell niches in vivo. Regenerative Medicine. 3: 365-76. PMID 18462059 DOI: 10.2217/17460751.3.3.365 |
0.823 |
|
2007 |
Cerdan C, Hong SH, Bhatia M. Formation and hematopoietic differentiation of human embryoid bodies by suspension and hanging drop cultures. Current Protocols in Stem Cell Biology. Unit 1D.2. PMID 18770624 DOI: 10.1002/9780470151808.Sc01D02S3 |
0.581 |
|
2007 |
Bhatia M. Hematopoietic development from human embryonic stem cells. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 11-6. PMID 18024603 DOI: 10.1182/Asheducation-2007.1.11 |
0.608 |
|
2007 |
Bendall SC, Stewart MH, Menendez P, George D, Vijayaragavan K, Werbowetski-Ogilvie T, Ramos-Mejia V, Rouleau A, Yang J, Bossé M, Lajoie G, Bhatia M. IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature. 448: 1015-21. PMID 17625568 DOI: 10.1038/Nature06027 |
0.817 |
|
2007 |
Vijayaragavan K, Bhatia M. Early cardiac development: a Wnt beat away. Proceedings of the National Academy of Sciences of the United States of America. 104: 9549-50. PMID 17537915 DOI: 10.1073/Pnas.0703731104 |
0.357 |
|
2007 |
Sullivan KE, Reddy AB, Dietzmann K, Suriano AR, Kocieda VP, Stewart M, Bhatia M. Epigenetic regulation of tumor necrosis factor alpha. Molecular and Cellular Biology. 27: 5147-60. PMID 17515611 DOI: 10.1128/Mcb.02429-06 |
0.721 |
|
2007 |
Bhatia M. Hematopoiesis from human embryonic stem cells. Annals of the New York Academy of Sciences. 1106: 219-22. PMID 17332088 DOI: 10.1196/Annals.1392.007 |
0.612 |
|
2007 |
Stewart M, Bhatia M. A not-so-rough guide to genes and cloning Nature Cell Biology. 9: 1336-1336. DOI: 10.1038/Ncb1207-1336 |
0.666 |
|
2006 |
Cerdan C, Bendall SC, Wang L, Stewart M, Werbowetski T, Bhatia M. Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells. Nature Medicine. 12: 1113-4; author reply. PMID 17024197 DOI: 10.1038/Nm1006-1113 |
0.801 |
|
2006 |
Stewart MH, Bossé M, Chadwick K, Menendez P, Bendall SC, Bhatia M. Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment. Nature Methods. 3: 807-15. PMID 16990813 DOI: 10.1038/Nmeth939 |
0.806 |
|
2006 |
Trowbridge JJ, Moon RT, Bhatia M. Hematopoietic stem cell biology: too much of a Wnt thing. Nature Immunology. 7: 1021-3. PMID 16985497 DOI: 10.1038/Ni1006-1021 |
0.573 |
|
2006 |
Trowbridge JJ, Scott MP, Bhatia M. Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration. Proceedings of the National Academy of Sciences of the United States of America. 103: 14134-9. PMID 16968775 DOI: 10.1073/Pnas.0604568103 |
0.546 |
|
2006 |
Cerdan C, Bhatia M. [Human embryonic stem cell and haematopoiesis: comparison with the mouse]. MéDecine Sciences : M/S. 22: 705-7. PMID 16962042 DOI: 10.1051/Medsci/20062289705 |
0.611 |
|
2006 |
Menendez P, Wang L, Cerdan C, Bhatia M. Retroviral transduction of hematopoietic progenitors derived from human embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 331: 201-20. PMID 16881519 DOI: 10.1385/1-59745-046-4:201 |
0.64 |
|
2006 |
Wang L, Cerdan C, Menendez P, Bhatia M. Derivation and characterization of hematopoietic cells from human embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 331: 179-200. PMID 16881518 DOI: 10.1385/1-59745-046-4:179 |
0.613 |
|
2006 |
Trowbridge JJ, Xenocostas A, Moon RT, Bhatia M. Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nature Medicine. 12: 89-98. PMID 16341242 DOI: 10.1038/Nm1339 |
0.511 |
|
2006 |
Trowbridge J, Xenocostas A, Moon R, Bhatia M. Glycogen synthase kinase-3 is an in vivo regulator of human hemopoietic stem cells Biology of Blood and Marrow Transplantation. 12: 106. DOI: 10.1016/J.Bbmt.2005.11.327 |
0.537 |
|
2005 |
Menendez P, Bueno C, Wang L, Bhatia M. Human embryonic stem cells: potential tool for achieving immunotolerance? Stem Cell Reviews. 1: 151-8. PMID 17142850 DOI: 10.1385/Scr:1:2:151 |
0.568 |
|
2005 |
Martin MA, Bhatia M. Analysis of the human fetal liver hematopoietic microenvironment. Stem Cells and Development. 14: 493-504. PMID 16305335 DOI: 10.1089/Scd.2005.14.493 |
0.521 |
|
2005 |
Levac K, Menendez P, Bhatia M. Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/beta2m(-/-) mice. Experimental Hematology. 33: 1417-26. PMID 16263425 DOI: 10.1016/J.Exphem.2005.07.007 |
0.38 |
|
2005 |
Rosu-Myles M, Stewart E, Trowbridge J, Ito CY, Zandstra P, Bhatia M. A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis. Journal of Cell Science. 118: 4343-52. PMID 16144866 DOI: 10.1242/Jcs.02555 |
0.724 |
|
2005 |
Wang L, Menendez P, Cerdan C, Bhatia M. Hematopoietic development from human embryonic stem cell lines. Experimental Hematology. 33: 987-96. PMID 16140146 DOI: 10.1016/J.Exphem.2005.06.002 |
0.632 |
|
2005 |
Menendez P, Wang L, Bhatia M. Genetic manipulation of human embryonic stem cells: a system to study early human development and potential therapeutic applications. Current Gene Therapy. 5: 375-85. PMID 16101512 DOI: 10.2174/1566523054546198 |
0.528 |
|
2005 |
Bhatia M. Derivation of the hematopoietic stem cell compartment from human embryonic stem cell lines. Annals of the New York Academy of Sciences. 1044: 24-8. PMID 15958694 DOI: 10.1196/Annals.1349.004 |
0.597 |
|
2005 |
Allan DS, Gallacher L, Keeney M, Bhatia M, Chin-Yee I, Xenocostas A. Undetectable leukemic blasts and absence of NOD/SCID leukemia-initiating cells in cord blood from a case of maternal AML. Bone Marrow Transplantation. 36: 269-70. PMID 15937500 DOI: 10.1038/Sj.Bmt.1705035 |
0.339 |
|
2005 |
Wang L, Menendez P, Shojaei F, Li L, Mazurier F, Dick JE, Cerdan C, Levac K, Bhatia M. Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. The Journal of Experimental Medicine. 201: 1603-14. PMID 15883170 DOI: 10.1084/Jem.20041888 |
0.623 |
|
2005 |
Shojaei F, Trowbridge J, Gallacher L, Yuefei L, Goodale D, Karanu F, Levac K, Bhatia M. Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior. Developmental Cell. 8: 651-63. PMID 15866157 DOI: 10.1016/J.Devcel.2005.03.004 |
0.602 |
|
2005 |
Wang L, Li L, Menendez P, Cerdan C, Bhatia M. Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. Blood. 105: 4598-603. PMID 15718421 DOI: 10.1182/Blood-2004-10-4065 |
0.564 |
|
2005 |
Allan DS, Jay KE, Bhatia M. Hematopoietic capacity of adult human skeletal muscle is negligible. Bone Marrow Transplantation. 35: 663-6. PMID 15711572 DOI: 10.1038/Sj.Bmt.1704866 |
0.338 |
|
2005 |
Levac K, Karanu F, Bhatia M. Identification of growth factor conditions that reduce ex vivo cord blood progenitor expansion but do not alter human repopulating cell function in vivo. Haematologica. 90: 166-72. PMID 15710567 |
0.45 |
|
2005 |
Chadwick K, Shojaei F, Gallacher L, Bhatia M. Smad7 alters cell fate decisions of human hematopoietic repopulating cells. Blood. 105: 1905-15. PMID 15498852 DOI: 10.1182/Blood-2004-03-0881 |
0.526 |
|
2005 |
Bhatia M. Challenging the role of Notch in HSC biology Blood. 105: 2248-2248. DOI: 10.1182/Blood-2005-01-0008 |
0.444 |
|
2004 |
Menendez P, Wang L, Chadwick K, Li L, Bhatia M. Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45(neg)PFV hemogenic precursors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 1109-20. PMID 15564142 DOI: 10.1016/J.Ymthe.2004.08.016 |
0.57 |
|
2004 |
Jay KE, Rouleau A, Underhill TM, Bhatia M. Identification of a novel population of human cord blood cells with hema-topoietic and chondrocytic potential. Cell Research. 14: 268-82. PMID 15353124 DOI: 10.1038/Sj.Cr.7290228 |
0.473 |
|
2004 |
Wang L, Li L, Shojaei F, Levac K, Cerdan C, Menendez P, Martin T, Rouleau A, Bhatia M. Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity. 21: 31-41. PMID 15345218 DOI: 10.1016/J.Immuni.2004.06.006 |
0.549 |
|
2004 |
Li L, Baroja ML, Majumdar A, Chadwick K, Rouleau A, Gallacher L, Ferber I, Lebkowski J, Martin T, Madrenas J, Bhatia M. Human embryonic stem cells possess immune-privileged properties. Stem Cells (Dayton, Ohio). 22: 448-56. PMID 15277692 DOI: 10.1634/Stemcells.22-4-448 |
0.487 |
|
2004 |
Cerdan C, Rouleau A, Bhatia M. VEGF-A165 augments erythropoietic development from human embryonic stem cells. Blood. 103: 2504-12. PMID 14656883 DOI: 10.1182/Blood-2003-07-2563 |
0.463 |
|
2004 |
Shojaei F, Gallacher L, Bhatia M. Differential gene expression of human stem progenitor cells derived from early stages of in utero human hematopoiesis. Blood. 103: 2530-40. PMID 14656878 DOI: 10.1182/Blood-2003-09-3209 |
0.526 |
|
2003 |
Hess DA, Karanu FN, Levac K, Gallacher L, Bhatia M. Coculture and transplant of purified CD34(+)Lin(-) and CD34(-)Lin(-) cells reveals functional interaction between repopulating hematopoietic stem cells. Leukemia. 17: 1613-25. PMID 12886251 DOI: 10.1038/Sj.Leu.2403028 |
0.46 |
|
2003 |
Karanu FN, Yuefei L, Gallacher L, Sakano S, Bhatia M. Differential response of primitive human CD34- and CD34+ hematopoietic cells to the Notch ligand Jagged-1. Leukemia. 17: 1366-74. PMID 12835726 DOI: 10.1038/Sj.Leu.2402973 |
0.389 |
|
2003 |
Hess D, Li L, Martin M, Sakano S, Hill D, Strutt B, Thyssen S, Gray DA, Bhatia M. Bone marrow-derived stem cells initiate pancreatic regeneration. Nature Biotechnology. 21: 763-70. PMID 12819790 DOI: 10.1038/Nbt841 |
0.466 |
|
2003 |
Rosu-Myles M, Bhatia M. SDF-1 enhances the expansion and maintenance of highly purified human hematopoietic progenitors. The Hematology Journal : the Official Journal of the European Haematology Association / Eha. 4: 137-45. PMID 12750733 DOI: 10.1038/Sj.Thj.6200233 |
0.762 |
|
2003 |
Bhatia M. The ultimate source of human hematopoietic stem cells: thinking outside the marrow. Cloning and Stem Cells. 5: 89-97. PMID 12713705 DOI: 10.1089/153623003321512201 |
0.626 |
|
2003 |
Chadwick K, Wang L, Li L, Menendez P, Murdoch B, Rouleau A, Bhatia M. Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood. 102: 906-15. PMID 12702499 DOI: 10.1182/Blood-2003-03-0832 |
0.63 |
|
2003 |
Murdoch B, Chadwick K, Martin M, Shojaei F, Shah KV, Gallacher L, Moon RT, Bhatia M. Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 3422-7. PMID 12626754 DOI: 10.1073/Pnas.0130233100 |
0.525 |
|
2002 |
Chin-Yee I, Keeney M, Stewart A, Belch A, Bence-Buckler I, Couban S, Howson-Jan K, Rubinger M, Stewart D, Sutherland R, Paragamian V, Bhatia M, Foley R. Optimising parameters for peripheral blood leukapheresis after r-metHuG-CSF (filgrastim) and r-metHuSCF (ancestim) in patients with multiple myeloma: a temporal analysis of CD34(+) absolute counts and subsets. Bone Marrow Transplantation. 30: 851-860. PMID 12476276 DOI: 10.1038/Sj.Bmt.1703765 |
0.398 |
|
2002 |
Jay KE, Gallacher L, Bhatia M. Emergence of muscle and neural hematopoiesis in humans. Blood. 100: 3193-202. PMID 12384417 DOI: 10.1182/Blood-2002-02-0502 |
0.46 |
|
2002 |
Hess DA, Levac KD, Karanu FN, Rosu-Myles M, White MJ, Gallacher L, Murdoch B, Keeney M, Ottowski P, Foley R, Chin-Yee I, Bhatia M. Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor. Blood. 100: 869-78. PMID 12130497 DOI: 10.1182/Blood.V100.3.869 |
0.724 |
|
2002 |
Allan DS, Keeney M, Howson-Jan K, Popma J, Weir K, Bhatia M, Sutherland DR, Chin-Yee IH. Number of viable CD34(+) cells reinfused predicts engraftment in autologous hematopoietic stem cell transplantation. Bone Marrow Transplantation. 29: 967-972. PMID 12098064 DOI: 10.1038/Sj.Bmt.1703575 |
0.491 |
|
2002 |
Wilpshaar J, Bhatia M, Kanhai HH, Breese R, Heilman DK, Johnson CS, Falkenburg JH, Srour EF. Engraftment potential of human fetal hematopoietic cells in NOD/SCID mice is not restricted to mitotically quiescent cells. Blood. 100: 120-7. PMID 12070016 DOI: 10.1182/Blood.V100.1.120 |
0.544 |
|
2002 |
Murdoch B, Gallacher L, Chadwick K, Fellows F, Bhatia M. Human embryonic-derived hematopoietic repopulating cells require distinct factors to sustain in vivo repopulating function. Experimental Hematology. 30: 598-605. PMID 12063027 DOI: 10.1016/S0301-472X(02)00793-2 |
0.611 |
|
2002 |
Murdoch B, Gallacher L, Chadwick K, Bhatia M. Characterization of retroviral gene transfer into highly purified human CD34(-) cells with primitive hematopoietic capacity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 635-43. PMID 11991755 DOI: 10.1006/Mthe.2002.0583 |
0.403 |
|
2001 |
Bhatia M. AC133 expression in human stem cells. Leukemia. 15: 1685-8. PMID 11681407 DOI: 10.1038/Sj.Leu.2402255 |
0.613 |
|
2001 |
Murdoch B, Gallacher L, Awaraji C, Hess DA, Keeney M, Jay K, Chadwick K, Fowley SR, Howson-Jan K, Chin Yee I, Wu D, Srour ED, Fellows F, Bhatia M. Circulating hematopoietic stem cells serve as novel targets for in utero gene therapy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1628-30. PMID 11427508 DOI: 10.1096/Fj.00-0654Fje |
0.579 |
|
2001 |
Karanu FN, Murdoch B, Miyabayashi T, Ohno M, Koremoto M, Gallacher L, Wu D, Itoh A, Sakano S, Bhatia M. Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells Blood. 97: 1960-1967. PMID 11264159 DOI: 10.1182/Blood.V97.7.1960 |
0.551 |
|
2001 |
Bhardwaj G, Murdoch B, Wu D, Baker DP, Williams KP, Chadwick K, Ling LE, Karanu FN, Bhatia M. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation Nature Immunology. 2: 172-180. PMID 11175816 DOI: 10.1038/84282 |
0.585 |
|
2000 |
Rosu-Myles M, Gallacher L, Murdoch B, Hess DA, Keeney M, Kelvin D, Dale L, Ferguson SS, Wu D, Fellows F, Bhatia M. The human hematopoietic stem cell compartment is heterogeneous for CXCR4 expression. Proceedings of the National Academy of Sciences of the United States of America. 97: 14626-31. PMID 11121064 DOI: 10.1073/Pnas.97.26.14626 |
0.792 |
|
2000 |
Karanu FN, Murdoch B, Gallacher L, Wu DM, Koremoto M, Sakano S, Bhatia M. The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells. The Journal of Experimental Medicine. 192: 1365-72. PMID 11067884 DOI: 10.1084/Jem.192.9.1365 |
0.633 |
|
2000 |
Rosu-Myles M, Khandaker M, Wu DM, Keeney M, Foley SR, Howson-Jan K, Chin Yee I, Fellows F, Kelvin D, Bhatia M. Characterization of chemokine receptors expressed in primitive blood cells during human hematopoietic ontogeny Stem Cells. 18: 374-381. PMID 11007922 DOI: 10.1634/Stemcells.18-5-374 |
0.753 |
|
2000 |
Gao JX, Zhang J, Awaraji C, Bhatia M, Jevnikar A, Singh B, Bell D, Delovitch TL. Preferential proliferation and differentiation of double-positive thymocytes into CD8(+) single-positive thymocytes in a novel cell culture medium. Cellular Immunology. 202: 41-53. PMID 10873305 DOI: 10.1006/Cimm.2000.1656 |
0.44 |
|
2000 |
Gallacher L, Murdoch B, Wu D, Karanu F, Fellows F, Bhatia M. Identification of novel circulating human embryonic blood stem cells Blood. 96: 1740-1747. DOI: 10.1182/Blood.V96.5.1740.H8001740_1740_1747 |
0.612 |
|
2000 |
Gallacher L, Murdoch B, Wu DM, Karanu FN, Keeney M, Bhatia M. Isolation and characterization of human CD34−Lin− and CD34+Lin− hematopoietic stem cells using cell surface markers AC133 and CD7 Blood. 95: 2813-2820. DOI: 10.1182/Blood.V95.9.2813.009K20_2813_2820 |
0.579 |
|
1999 |
Bhatia M, Bonnet D, Wu D, Murdoch B, Wrana J, Gallacher L, Dick JE. Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. The Journal of Experimental Medicine. 189: 1139-48. PMID 10190905 DOI: 10.1084/Jem.189.7.1139 |
0.627 |
|
1999 |
Bonnet D, Bhatia M, Wang JC, Kapp U, Dick JE. Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice. Bone Marrow Transplantation. 23: 203-9. PMID 10084250 DOI: 10.1038/Sj.Bmt.1701564 |
0.478 |
|
1998 |
Bhatia M, Bonnet D, Murdoch B, Gan OI, Dick JE. A newly discovered class of human hematopoietic cells with SCID-repopulating activity. Nature Medicine. 4: 1038-45. PMID 9734397 DOI: 10.1038/2023 |
0.55 |
|
1998 |
Kapp U, Bhatia M, Bonnet D, Murdoch B, Dick JE. Treatment of Non-Obese Diabetic (NOD)/Severe-Combined Immunodeficient Mice (SCID) With flt3 Ligand and Interleukin-7 Impairs the B-Lineage Commitment of Repopulating Cells After Transplantation of Human Hematopoietic Cells Blood. 92: 2024-2031. DOI: 10.1182/blood.v92.6.2024.418k12_2024_2031 |
0.417 |
|
1998 |
Kapp U, Bhatia M, Bonnet D, Murdoch B, Dick JE. Treatment of Non-Obese Diabetic (NOD)/Severe-Combined Immunodeficient Mice (SCID) With flt3 Ligand and Interleukin-7 Impairs the B-Lineage Commitment of Repopulating Cells After Transplantation of Human Hematopoietic Cells Blood. 92: 2024-2031. DOI: 10.1182/Blood.V92.6.2024 |
0.511 |
|
1997 |
Dick JE, Bhatia M, Gan O, Kapp U, Wang JC. Assay of human stem cells by repopulation of NOD/SCID mice. Stem Cells (Dayton, Ohio). 199-203; discussion . PMID 9368342 DOI: 10.1002/Stem.5530150826 |
0.599 |
|
1997 |
Bhatia M, Bonnet D, Kapp U, Wang JC, Murdoch B, Dick JE. Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture. The Journal of Experimental Medicine. 186: 619-24. PMID 9254660 DOI: 10.1084/Jem.186.4.619 |
0.504 |
|
1997 |
Bhatia M, Wang JC, Kapp U, Bonnet D, Dick JE. Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 5320-5. PMID 9144235 DOI: 10.1073/Pnas.94.10.5320 |
0.543 |
|
1996 |
Larochelle A, Vormoor J, Hanenberg H, Wang JCY, Bhatia M, Lapidot T, Moritz T, Murdoch B, Xiao XL, Kato I, Williams DA, Dick JE. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy Nature Medicine. 2: 1329-1337. PMID 8946831 DOI: 10.1038/Nm1296-1329 |
0.513 |
|
1996 |
Bhatia M, Kirkland JB, Meckling-Gill KA. 1,25-dihydroxyvitamin D3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades. Experimental Cell Research. 222: 61-9. PMID 8549674 DOI: 10.1006/Excr.1996.0008 |
0.368 |
|
1995 |
Bhatia M, Kirkland JB, Meckling-Gill KA. Modulation of poly(ADP-ribose) polymerase during neutrophilic and monocytic differentiation of promyelocytic (NB4) and myelocytic (HL-60) leukaemia cells. The Biochemical Journal. 131-7. PMID 7755555 DOI: 10.1042/Bj3080131 |
0.501 |
|
1995 |
Bhatia M, Kirkland JB, Meckling-Gill KA. Monocytic differentiation of acute promyelocytic leukemia cells in response to 1,25-dihydroxyvitamin D3 is independent of nuclear receptor binding. The Journal of Biological Chemistry. 270: 15962-5. PMID 7608152 DOI: 10.1074/Jbc.270.27.15962 |
0.341 |
|
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