Anton K. Raap - Publications

Affiliations: 
Cytochemistry and Cytometry Leiden University, Leiden, Netherlands 
Area:
molecular cytogenetics, mitochondrial dysfunction and its consequences on cellular signaling and disease development

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Raap AK, Tanke HJ. COmbined Binary RAtio fluorescence in situ hybridiziation (COBRA-FISH): development and applications. Cytogenetic and Genome Research. 114: 222-6. PMID 16954657 DOI: 10.1159/000094204  0.362
2006 Dijkman R, Tensen CP, Jordanova ES, Knijnenburg J, Hoefnagel JJ, Mulder AA, Rosenberg C, Raap AK, Willemze R, Szuhai K, Vermeer MH. Array-based comparative genomic hybridization analysis reveals recurrent chromosomal alterations and prognostic parameters in primary cutaneous large B-cell lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 296-305. PMID 16330669 DOI: 10.1200/Jco.2005.02.0842  0.397
2005 Vries RG, Bezrookove V, Zuijderduijn LM, Kia SK, Houweling A, Oruetxebarria I, Raap AK, Verrijzer CP. Cancer-associated mutations in chromatin remodeler hSNF5 promote chromosomal instability by compromising the mitotic checkpoint. Genes & Development. 19: 665-70. PMID 15769941 DOI: 10.1101/Gad.335805  0.363
2005 Guikema JE, Fenton JA, de Boer C, Kleiverda K, Brink AA, Raap AK, Estrov Z, Schuuring E, Kluin PM. Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination. Genes, Chromosomes & Cancer. 42: 164-9. PMID 15543623 DOI: 10.1002/Gcc.20132  0.385
2004 Larsson C, Koch J, Nygren A, Janssen G, Raap AK, Landegren U, Nilsson M. In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes. Nature Methods. 1: 227-32. PMID 15782198 DOI: 10.1038/Nmeth723  0.361
2004 Ferber MJ, Eilers P, Schuuring E, Fenton JA, Fleuren GJ, Kenter G, Szuhai K, Smith DI, Raap AK, Brink AA. Positioning of cervical carcinoma and Burkitt lymphoma translocation breakpoints with respect to the human papillomavirus integration cluster in FRA8C at 8q24.13. Cancer Genetics and Cytogenetics. 154: 1-9. PMID 15381365 DOI: 10.1016/J.Cancergencyto.2004.01.028  0.331
2004 Wiegant J, Brouwer K, Bezrookove V, Smits S, Raap AK, Bout A, Tanke HJ. Molecular cytogenetic characterization by combined COBRA-FISH and fiber-FISH: application to PER.C6 cells. Biotechniques. 37: 188, 190, 192 passim. PMID 15335206 DOI: 10.2144/04372Bm02  0.389
2004 Wu Y, de Kievit P, Vahlkamp L, Pijnenburg D, Smit M, Dankers M, Melchers D, Stax M, Boender PJ, Ingham C, Bastiaensen N, de Wijn R, van Alewijk D, van Damme H, Raap AK, et al. Quantitative assessment of a novel flow-through porous microarray for the rapid analysis of gene expression profiles. Nucleic Acids Research. 32: e123. PMID 15333674 DOI: 10.1093/Nar/Gnh118  0.331
2004 Raap AK, van der Burg MJ, Knijnenburg J, Meershoek E, Rosenberg C, Gray JW, Wiegant J, Hodgson JG, Tanke HJ. Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs. Biotechniques. 37: 130-4. PMID 15283211 DOI: 10.2144/04371Dd03  0.373
2004 Bezrookove V, van Zelderen-Bhola SL, Brink A, Szuhai K, Raap AK, Barge R, Beverstock GC, Rosenberg C. A novel t(6;14)(q25-q27;q32) in acute myelocytic leukemia involves the BCL11B gene. Cancer Genetics and Cytogenetics. 149: 72-6. PMID 15104287 DOI: 10.1016/S0165-4608(03)00302-9  0.362
2003 van de Rijke FM, Heetebrij RJ, Talman EG, Tanke HJ, Raap AK. Fluorescence properties, thermal duplex stability, and kinetics of formation of cyanin platinum DNAs. Analytical Biochemistry. 321: 71-8. PMID 12963057 DOI: 10.1016/S0003-2697(03)00430-5  0.404
2003 Bezrookove V, Smits R, Moeslein G, Fodde R, Tanke HJ, Raap AK, Darroudi F. Premature chromosome condensation revisited: a novel chemical approach permits efficient cytogenetic analysis of cancers. Genes, Chromosomes & Cancer. 38: 177-86. PMID 12939745 DOI: 10.1002/Gcc.10268  0.408
2003 Engels H, Ehrbrecht A, Zahn S, Bosse K, Vrolijk H, White S, Kalscheuer V, Hoovers JM, Schwanitz G, Propping P, Tanke HJ, Wiegant J, Raap AK. Comprehensive analysis of human subtelomeres with combined binary ratio labelling fluorescence in situ hybridisation. European Journal of Human Genetics : Ejhg. 11: 643-51. PMID 12939649 DOI: 10.1038/Sj.Ejhg.5201028  0.458
2003 Heetebrij RJ, Talman EG, v Velzen MA, van Gijlswijk RP, Snoeijers SS, Schalk M, Wiegant J, v d Rijke F, Kerkhoven RM, Raap AK, Tanke HJ, Reedijk J, Houthoff HJ. Platinum(II)-based coordination compounds as nucleic acid labeling reagents: synthesis, reactivity, and applications in hybridization assays. Chembiochem : a European Journal of Chemical Biology. 4: 573-83. PMID 12851925 DOI: 10.1002/Cbic.200200498  0.348
2003 Hagedoorn R, Joseph R, Kasanmoentalib S, Eilers P, Killian J, Raap AK. Chemical RNA labeling without 3' end bias using fluorescent cis-platin compounds. Biotechniques. 34: 974-6, 978, 980. PMID 12765024 DOI: 10.2144/03345St03  0.369
2002 Nilsson M, Gullberg M, Dahl F, Szuhai K, Raap AK. Real-time monitoring of rolling-circle amplification using a modified molecular beacon design. Nucleic Acids Research. 30: e66. PMID 12136114 DOI: 10.1093/Nar/Gnf065  0.4
2002 Brink AA, Wiegant JC, Szuhai K, Tanke HJ, Kenter GG, Fleuren GJ, Schuuring E, Raap AK. Simultaneous mapping of human papillomavirus integration sites and molecular karyotyping in short-term cultures of cervical carcinomas by using 49-color combined binary ratio labeling fluorescence in situ hybridization. Cancer Genetics and Cytogenetics. 134: 145-50. PMID 12034529 DOI: 10.1016/S0165-4608(01)00620-3  0.315
2001 Wiegant J, Raap AK. Probe labeling and fluorescence in situ hybridization. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 8.3. PMID 18770741 DOI: 10.1002/0471142956.cy0803s00  0.33
2001 Wiegant J, Raap AK. Basic preparative techniques for fluorescence in situ hybridization. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 8.2. PMID 18770740 DOI: 10.1002/0471142956.cy0802s00  0.313
2001 Molenaar C, Marras SA, Slats JC, Truffert JC, Lemaître M, Raap AK, Dirks RW, Tanke HJ. Linear 2' O-Methyl RNA probes for the visualization of RNA in living cells. Nucleic Acids Research. 29: E89-9. PMID 11522845 DOI: 10.1093/Nar/29.17.E89  0.326
2001 van De Rijke F, Zijlmans H, Li S, Vail T, Raap AK, Niedbala RS, Tanke HJ. Up-converting phosphor reporters for nucleic acid microarrays. Nature Biotechnology. 19: 273-6. PMID 11231563 DOI: 10.1038/85734  0.376
2000 Wiegant J, Bezrookove V, Rosenberg C, Tanke HJ, Raap AK, Zhang H, Bittner M, Trent JM, Meltzer P. Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization. Genome Research. 10: 861-5. PMID 10854417 DOI: 10.1101/Gr.10.6.861  0.456
2000 Bezrookove V, Hansson K, van der Burg M, van der Smagt JJ, Hilhorst-Hofstee Y, Wiegant J, Beverstock GC, Raap AK, Tanke H, Breuning MH, Rosenberg C. Individuals with abnormal phenotype and normal G-banding karyotype: improvement and limitations in the diagnosis by the use of 24-colour FISH. Human Genetics. 106: 392-8. PMID 10830905 DOI: 10.1007/S004390000268  0.352
2000 van de Rijke FM, Florijn RJ, Tanke HJ, Raap AK. DNA fiber-FISH staining mechanism. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 48: 743-5. PMID 10820147 DOI: 10.1177/002215540004800602  0.407
2000 van Gijlswijk RP, van de Corput MP, Bezrookove V, Wiegant J, Tanke HJ, Raap AK. Synthesis and purification of horseradish peroxidase-labeled oligonucleotides for tyramide-based fluorescence in situ hybridization. Histochemistry and Cell Biology. 113: 175-80. PMID 10817671 DOI: 10.1007/S004180050436  0.449
2000 van den Ouweland JM, de Klerk JB, van de Corput MP, Dirks RW, Raap AK, Scholte HR, Huijmans JG, Hart LM, Bruining GJ, Maassen JA. Characterization of a novel mitochondrial DNA deletion in a patient with a variant of the Pearson marrow-pancreas syndrome. European Journal of Human Genetics : Ejhg. 8: 195-203. PMID 10780785 DOI: 10.1038/Sj.Ejhg.5200444  0.37
2000 Szuhai K, Bezrookove V, Wiegant J, Vrolijk J, Dirks RW, Rosenberg C, Raap AK, Tanke HJ. Simultaneous molecular karyotyping and mapping of viral DNA integration sites by 25-color COBRA-FISH. Genes, Chromosomes & Cancer. 28: 92-7. PMID 10738307 DOI: 10.1002/(Sici)1098-2264(200005)28:1<92::Aid-Gcc11>3.0.Co;2-2  0.458
1999 Wiegant JC, van Gijlswijk RP, Heetebrij RJ, Bezrookove V, Raap AK, Tanke HJ. ULS: a versatile method of labeling nucleic acids for FISH based on a monofunctional reaction of cisplatin derivatives with guanine moieties. Cytogenetics and Cell Genetics. 87: 47-52. PMID 10640810  0.331
1999 Cheung VG, Dalrymple HL, Narasimhan S, Watts J, Schuler G, Raap AK, Morley M, Bruzel A. A resource of mapped human bacterial artificial chromosome clones. Genome Research. 9: 989-93. PMID 10523527 DOI: 10.1101/Gr.9.10.989  0.41
1999 Alers JC, Rochat J, Krijtenburg PJ, van Dekken H, Raap AK, Rosenberg C. Universal linkage system: an improved method for labeling archival DNA for comparative genomic hybridization. Genes, Chromosomes & Cancer. 25: 301-5. PMID 10379877 DOI: 10.1002/(Sici)1098-2264(199907)25:3<301::Aid-Gcc13>3.0.Co;2-1  0.409
1999 Tanke HJ, Wiegant J, van Gijlswijk RP, Bezrookove V, Pattenier H, Heetebrij RJ, Talman EG, Raap AK, Vrolijk J. New strategy for multi-colour fluorescence in situ hybridisation: COBRA: COmbined Binary RAtio labelling. European Journal of Human Genetics : Ejhg. 7: 2-11. PMID 10094185 DOI: 10.1038/Sj.Ejhg.5200265  0.424
1998 Rosenberg C, Mostert MC, Schut TB, van de Pol M, van Echten J, de Jong B, Raap AK, Tanke H, Oosterhuis JW, Looijenga LH. Chromosomal constitution of human spermatocytic seminomas: comparative genomic hybridization supported by conventional and interphase cytogenetics. Genes, Chromosomes & Cancer. 23: 286-91. PMID 9824200 DOI: 10.1002/(Sici)1098-2264(199812)23:4<286::Aid-Gcc2>3.0.Co;2-6  0.428
1998 van de Corput MP, Dirks RW, van Gijlswijk RP, van de Rijke FM, Raap AK. Fluorescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification for sensitive DNA and mRNA detection. Histochemistry and Cell Biology. 110: 431-7. PMID 9792422  0.385
1998 van de Corput MP, Dirks RW, van Gijlswijk RP, van Binnendijk E, Hattinger CM, de Paus RA, Landegent JE, Raap AK. Sensitive mRNA detection by fluorescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 46: 1249-59. PMID 9774624 DOI: 10.1177/002215549804601105  0.412
1998 Chaves I, Zomerdijk J, Dirks-Mulder A, Dirks RW, Raap AK, Borst P. Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America. 95: 12328-33. PMID 9770486 DOI: 10.1073/Pnas.95.21.12328  0.32
1998 Vaandrager JW, Schuuring E, Kluin-Nelemans HC, Dyer MJ, Raap AK, Kluin PM. DNA fiber fluorescence in situ hybridization analysis of immunoglobulin class switching in B-cell neoplasia: aberrant CH gene rearrangements in follicle center-cell lymphoma. Blood. 92: 2871-8. PMID 9763572 DOI: 10.1182/Blood.V92.8.2871.420K08_2871_2878  0.345
1998 Rosenberg C, van Gijlswijk RP, Vos CB, Wiegant J, Cornelisse CJ, Tanke HJ, Raap AK. Comparative genomic hybridization with lissamine- and fluorescein-labeled nucleotides. Cytometry. 32: 337-41. PMID 9701403 DOI: 10.1002/(Sici)1097-0320(19980801)32:4<337::Aid-Cyto11>3.0.Co;2-N  0.352
1998 Raap AK. Advances in fluorescence in situ hybridization. Mutation Research. 400: 287-98. PMID 9685683 DOI: 10.1016/S0027-5107(98)00029-3  0.432
1998 de Pauw ES, Verwoerd NP, Duinkerken N, Willemze R, Raap AK, Fibbe WE, Tanke HJ. Assessment of telomere length in hematopoietic interphase cells using in situ hybridization and digital fluorescence microscopy. Cytometry. 32: 163-9. PMID 9667504 DOI: 10.1002/(Sici)1097-0320(19980701)32:3<163::Aid-Cyto1>3.0.Co;2-L  0.467
1998 Van De Corput MPC, Dirks RW, Van Gijlswijk RPM, Van De Rijke FM, Raap AK. Flourescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification for sensitive DNA and mRNA detection Histochemistry and Cell Biology. 110: 431-437. DOI: 10.1007/s004180050304  0.337
1997 van de Corput MP, Dirks RW, Wiegant WW, Wiegant J, Mühlegger K, Raap AK. Oestradiol, a new hapten for detecting nucleic acid sequences by FISH. Histochemistry and Cell Biology. 108: 359-64. PMID 9387928 DOI: 10.1007/s004180050176  0.319
1997 Rosenberg C, Schut TB, Mostert MC, Tanke HJ, Raap AK, Oosterhuis JW, Looijenga LH. Comparative genomic hybridization in hypotriploid/hyperdiploid tumors. Cytometry. 29: 113-21. PMID 9332817 DOI: 10.1002/(Sici)1097-0320(19971001)29:2<113::Aid-Cyto3>3.0.Co;2-E  0.428
1997 Zijlmans JM, Martens UM, Poon SS, Raap AK, Tanke HJ, Ward RK, Lansdorp PM. Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats. Proceedings of the National Academy of Sciences of the United States of America. 94: 7423-8. PMID 9207107 DOI: 10.1073/Pnas.94.14.7423  0.385
1997 Dierlamm J, Rosenberg C, Stul M, Pittaluga S, Wlodarska I, Michaux L, Dehaen M, Verhoef G, Thomas J, de Kelver W, Bakker-Schut T, Cassiman JJ, Raap AK, De Wolf-Peeters C, Van den Berghe H, et al. Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization. Leukemia. 11: 747-58. PMID 9180302 DOI: 10.1038/Sj.Leu.2400635  0.406
1997 van Gijlswijk RP, Zijlmans HJ, Wiegant J, Bobrow MN, Erickson TJ, Adler KE, Tanke HJ, Raap AK. Fluorochrome-labeled tyramides: use in immunocytochemistry and fluorescence in situ hybridization. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 45: 375-82. PMID 9071319 DOI: 10.1177/002215549704500305  0.448
1997 Garcia-Isidoro M, Tabernero MD, Garcia JL, Najera ML, Hernandez JM, Wiegant J, Raap A, San Miguel J, Orfao A. Detection of the Mbcr/abl translocation in chronic myeloid leukemia by fluorescence in situ hybridization: Comparison with conventional cytogenetics and implications for minimal residual disease detection Human Pathology. 28: 154-159. PMID 9023395 DOI: 10.1016/S0046-8177(97)90099-X  0.333
1997 van de Corput MP, van den Ouweland JM, Dirks RW, Hart LM, Bruining GJ, Maassen JA, Raap AK. Detection of mitochondrial DNA deletions in human skin fibroblasts of patients with Pearson's syndrome by two-color fluorescence in situ hybridization. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 45: 55-61. PMID 9010469 DOI: 10.1177/002215549704500108  0.34
1996 Florijn RJ, Bonnet J, Vrolijk H, Raap AK, Tanke HJ. Effect of chromatic errors in microscopy on the visualization of multi-color fluorescence in situ hybridization. Cytometry. 23: 8-14. PMID 14650435 DOI: 10.1002/(Sici)1097-0320(19960101)23:1<8::Aid-Cyto2>3.0.Co;2-I  0.359
1996 Raap AK, Florijn RJ, Blonden LAJ, Wiegant J, Vaandrager JW, Vrolijk H, den Dunnen J, Tanke HJ, van Ommen GJ. Fiber FISH as a DNA Mapping Tool Methods (San Diego, Calif.). 9: 67-73. PMID 9245344 DOI: 10.1006/Meth.1996.0009  0.369
1996 van Gijlswijk RP, Wiegant J, Vervenne R, Lasan R, Tanke HJ, Raap AK. Horseradish peroxidase-labeled oligonucleotides and fluorescent tyramides for rapid detection of chromosome-specific repeat sequences. Cytogenetics and Cell Genetics. 75: 258-62. PMID 9067437  0.361
1996 Mesker WE, Alers JC, Sloos WC, Vrolijk H, Raap AK, Dekken HV, Tanke HJ. Automated assessment of numerical chromosomal aberrations in paraffin embedded prostate tumor cells stained by in situ hybridization. Cytometry. 26: 298-304. PMID 8979030 DOI: 10.1002/(Sici)1097-0320(19961215)26:4<298::Aid-Cyto10>3.0.Co;2-M  0.388
1996 Boerman RH, Anderl K, Herath J, Borell T, Johnson N, Schaeffer-Klein J, Kirchhof A, Raap AK, Scheithauer BW, Jenkins RB. The glial and mesenchymal elements of gliosarcomas share similar genetic alterations. Journal of Neuropathology and Experimental Neurology. 55: 973-81. PMID 8800093 DOI: 10.1097/00005072-199609000-00004  0.409
1996 Lansdorp PM, Verwoerd NP, van de Rijke FM, Dragowska V, Little MT, Dirks RW, Raap AK, Tanke HJ. Heterogeneity in telomere length of human chromosomes. Human Molecular Genetics. 5: 685-91. PMID 8733138 DOI: 10.1093/Hmg/5.5.685  0.445
1996 Vrolijk H, Sloos WC, van de Rijke FM, Mesker WE, Netten H, Young IT, Raap AK, Tanke HJ. Automation of spot counting in interphase cytogenetics using brightfield microscopy. Cytometry. 24: 158-66. PMID 8725665 DOI: 10.1002/(Sici)1097-0320(19960601)24:2<158::Aid-Cyto8>3.0.Co;2-F  0.461
1996 van de Rijke FM, Vrolijk H, Sloos W, Tanke HJ, Raap AK. Sample preparation and in situ hybridization techniques for automated molecular cytogenetic analysis of white blood cells. Cytometry. 24: 151-7. PMID 8725664 DOI: 10.1002/(Sici)1097-0320(19960601)24:2<151::Aid-Cyto7>3.0.Co;2-M  0.403
1996 Vaandrager JW, Schuuring E, Zwikstra E, de Boer CJ, Kleiverda KK, van Krieken JH, Kluin-Nelemans HC, van Ommen GJ, Raap AK, Kluin PM. Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization. Blood. 88: 1177-82. PMID 8695834 DOI: 10.1182/Blood.V88.4.1177.Bloodjournal8841177  0.454
1996 Tabernero D, San Miguel JF, Garcia-Sanz M, Nájera L, García-Isidoro M, Peréz-Simon JA, Gonzalez M, Wiegant J, Raap AK, Orfão A. Incidence of chromosome numerical changes in multiple myeloma: fluorescence in situ hybridization analysis using 15 chromosome-specific probes. The American Journal of Pathology. 149: 153-61. PMID 8686739  0.357
1996 Coignet LJ, Van de Rijke FM, Vrolijk J, Bertheas MF, Raap AK, Tanke HJ. Automated counting of in situ hybridization dots in interphase cells of leukemia samples. Leukemia. 10: 1065-71. PMID 8667644  0.316
1996 Moers MH, Kalle WH, Ruiter AG, Wiegant JC, Raap AK, Greve J, de Grooth BG, van Hulst NF. Fluorescence in situ hybridization on human metaphase chromosomes detected by near-field scanning optical microscopy. Journal of Microscopy. 182: 40-5. PMID 8632445  0.358
1996 Wiegant J, Verwoerd N, Mascheretti S, Bolk M, Tanke HJ, Raap AK. An evaluation of a new series of fluorescent dUTPs for fluorescence in situ hybridization. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 44: 525-9. PMID 8627009  0.349
1996 Vrolijk H, Florijn RJ, Van De Rijke FM, Van Ommen GJB, Den Dunnen JT, Raap AK, Tanke HJ. Microscopy and image analysis of fibre-FISH Bioimaging. 4: 84-92. DOI: 10.1002/1361-6374(199606)4:2<84::Aid-Bio6>3.0.Co;2-8  0.309
1995 Dirks RW, Raap AK. Cell-cycle-dependent gene expression studied by two-colour fluorescent detection of a mRNA and histone mRNA. Histochemistry and Cell Biology. 104: 391-5. PMID 8574889 DOI: 10.1007/Bf01458133  0.319
1995 Tanke HJ, Florijn RJ, Wiegant J, Raap AK, Vrolijk J. CCD microscopy and image analysis of cells and chromosomes stained by fluorescence in situ hybridization. The Histochemical Journal. 27: 4-14. PMID 7713755 DOI: 10.1007/BF00164167  0.395
1995 Florijn RJ, Bonden LA, Vrolijk H, Wiegant J, Vaandrager JW, Baas F, den Dunnen JT, Tanke HJ, van Ommen GJ, Raap AK. High-resolution DNA Fiber-FISH for genomic DNA mapping and colour bar-coding of large genes. Human Molecular Genetics. 4: 831-6. PMID 7633442 DOI: 10.1093/Hmg/4.5.831  0.36
1995 Macville MV, Wiesmeijer KC, Dirks RW, Fransen JA, Raap AK. Saponin pre-treatment in pre-embedding electron microscopic in situ hybridization for detection of specific RNA sequences in cultured cells: a methodological study. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 43: 1005-18. PMID 7560878  0.311
1995 Tanke HJ, Florijn RJ, Vrolijk J, Raap AK. Molecular cytogenetics: unraveling of the genetic composition of individual cells by fluorescence in situ hybridization and digital imaging microscopy. World Journal of Urology. 13: 138-42. PMID 7550383 DOI: 10.1007/BF00184867  0.342
1995 van Ommen GJ, Breuning MH, Raap AK. FISH in genome research and molecular diagnostics. Current Opinion in Genetics & Development. 5: 304-8. PMID 7549423 DOI: 10.1016/0959-437X(95)80043-3  0.438
1994 Tagarro I, Wiegant J, Raap AK, González-Aguilera JJ, Fernández-Peralta AM. Assignment of human satellite 1 DNA as revealed by fluorescent in situ hybridization with oligonucleotides. Human Genetics. 93: 125-8. PMID 8112734 DOI: 10.1007/Bf00210595  0.473
1994 Raap AK, van de Rijke FM, Dirks RW. mRNA in situ hybridization to in vitro cultured cells. Methods in Molecular Biology (Clifton, N.J.). 33: 293-300. PMID 7894583 DOI: 10.1385/0-89603-280-9:293  0.341
1994 Raap AK, Wiegant J. Use of DNA-halo preparations for high-resolution DNA in situ hybridization. Methods in Molecular Biology (Clifton, N.J.). 33: 123-30. PMID 7894574 DOI: 10.1385/0-89603-280-9:123  0.37
1994 Ploem-Zaaijer JJ, Mesker WE, Boland GJ, Sloos WC, van de Rijke FM, Jiwa M, Raap AK. Automated image cytometry for detection of rare, viral antigen-positive cells in peripheral blood. Cytometry. 15: 199-206. PMID 7514521 DOI: 10.1002/Cyto.990150304  0.307
1993 Putman CAJ, De Grooth BG, Wiegant J, Raap AK, Van der Werf, Van Hulst NF, Greve J. Detection of in situ hybridization to human chromosomes Cytometry. 14: 356-361. PMID 8513692 DOI: 10.1002/cyto.990140403  0.365
1993 Kluck PM, Wiegant J, Jansen RP, Bolk MW, Raap AK, Willemze R, Landegent JE. The human interleukin-6 receptor alpha chain gene is localized on chromosome 1 band q21. Human Genetics. 90: 542-4. PMID 8428753 DOI: 10.1007/Bf00217455  0.38
1993 Dirks RW, van de Rijke FM, Fujishita S, van der Ploeg M, Raap AK. Methodologies for specific intron and exon RNA localization in cultured cells by haptenized and fluorochromized probes. Journal of Cell Science. 104: 1187-97. PMID 8391016  0.612
1993 Lewis JP, Tanke HJ, Raap AK, Kibbelaar RE, Kluin PM, Kluin-Nelemans HC. Hairy cell leukemia: an interphase cytogenetic study. Leukemia. 7: 1334-8. PMID 8371584  0.329
1993 Dirks RW, van Dorp AG, van Minnen J, Fransen JA, van der Ploeg M, Raap AK. Ultrastructural evidence for the axonal localization of caudodorsal cell hormone mRNA in the central nervous system of the mollusc Lymnaea stagnalis. Microscopy Research and Technique. 25: 12-8. PMID 8353303 DOI: 10.1002/Jemt.1070250104  0.61
1993 Alkema MJ, Wiegant J, Raap AK, Berns A, Van Lohuizen M. Characterization and chromosomal localization of the human proto-oncogene BMI-1 Human Molecular Genetics. 2: 1597-1603. PMID 8268912 DOI: 10.1093/Hmg/2.10.1597  0.404
1993 Dauwerse JG, Wessels JW, Giles RH, Wiegant J, Van der Reijden BA, Fugazza G, Jumelet EA, Smit E, Baas F, Raap AK, Hagemeijer A, Beverstock GC, Van Ommen GJB, Breuning MH. Cloning the breakpoint cluster region of the inv(16) in acute nonlymphocytic leukemia M4 Eo Human Molecular Genetics. 2: 1527-1534. PMID 8268905 DOI: 10.1093/Hmg/2.10.1527  0.417
1993 Lewis JP, Tanke HJ, Raap AK, Beverstock GC, Kluin-Nelemans HC. Somatic pairing of centromeres and short arms of chromosome 15 in the hematopoietic and lymphoid system. Human Genetics. 92: 577-82. PMID 8262518 DOI: 10.1007/Bf00420942  0.4
1993 Kibbelaar RE, Kok F, Dreef EJ, Kleiverda JK, Cornelisse CJ, Raap AK, Kluin PM. Statistical methods in interphase cytogenetics: An experimental approach Cytometry. 14: 716-724. PMID 8243201  0.309
1992 Smit VT, Wessels JW, Mollevanger P, Dauwerse JG, van Vliet M, Beverstock GC, Breuning MH, Devilee P, Raap AK, Cornelisse CJ. Improved interpretation of complex chromosomal rearrangements by combined GTG banding and in situ suppression hybridization using chromosome-specific libraries and cosmid probes. Genes, Chromosomes & Cancer. 3: 239-48. PMID 1958589 DOI: 10.1002/Gcc.2870030402  0.47
1992 Arnoldus EP, Wolters LB, Voormolen JH, van Duinen SG, Raap AK, van der Ploeg M, Peters AC. Interphase cytogenetics: a new tool for the study of genetic changes in brain tumors. Journal of Neurosurgery. 76: 997-1003. PMID 1588436 DOI: 10.3171/Jns.1992.76.6.0997  0.639
1992 Nederlof PM, Van der Flier S, Vrolijk J, Tanke HJ, Raap AK. Fluorescence ratio measurements of double-labeled probes for multiple in situ hybridization by digital imaging microscopy Cytometry. 13: 839-845. PMID 1459001 DOI: 10.1002/Cyto.990130806  0.406
1992 Nederlof PM, Van der Flier S, Raap AK, Tanke HJ. Quantification of inter- and intra-nuclear variation of fluorescence in situ hybridization signals Cytometry. 13: 831-838. PMID 1459000 DOI: 10.1002/cyto.990130805  0.367
1992 Dirks RW, Van Dorp AG, Van Minnen J, Fransen JA, Van der Ploeg M, Raap AK. Electron microscopic detection of RNA sequences by non-radioactive in situ hybridization in the mollusk Lymnaea stagnalis. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 40: 1647-57. PMID 1431053  0.622
1992 van Gijlswijk RPM, Raap AK, Tanke HJ. Quantification of sensitive non-isotopic filter hybridizations using the peroxidase catalyzed luminol reaction Molecular and Cellular Probes. 6: 223-230. PMID 1406730 DOI: 10.1016/0890-8508(92)90020-X  0.383
1992 Ried T, Lengauer C, Cremer T, Wiegant J, Raap AK, van der Ploeg M, Groitl P, Lipp M. Specific metaphase and interphase detection of the breakpoint region in 8q24 of Burkitt lymphoma cells by triple-color fluorescence in situ hybridization. Genes, Chromosomes & Cancer. 4: 69-74. PMID 1377011 DOI: 10.1002/Gcc.2870040109  0.73
1992 Kibbelaar RE, Mulder JW, van Kamp H, Dreef EJ, Wessels HW, Beverstock GC, Haak HL, Raap AK, Kluin PM. Nonradioactive in situ hybridisation of the translocation t(1;7) in myeloid malignancies. Genes, Chromosomes & Cancer. 4: 128-34. PMID 1373312 DOI: 10.1002/Gcc.2870040205  0.451
1992 Vlieger AM, Medenblik AM, van Gijlswijk RP, Tanke HJ, van der Ploeg M, Gratama JW, Raap AK. Quantitation of polymerase chain reaction products by hybridization-based assays with fluorescent, colorimetric, or chemiluminescent detection. Analytical Biochemistry. 205: 1-7. PMID 1332534 DOI: 10.1016/0003-2697(92)90570-W  0.58
1992 Arnoldus EP, Raap AK, Peters AC, van der Ploeg M. Interphase cytogenetic analysis of gliomas. Clinical Neurology and Neurosurgery. 94: S34-5. PMID 1320511 DOI: 10.1016/0303-8467(92)90015-U  0.645
1992 Boerman RH, Peters AC, Bloem BR, Raap AK, van der Ploeg M. Spread of herpes simplex virus to the cerebrospinal fluid and the meninges in experimental mouse encephalitis. Acta Neuropathologica. 83: 300-7. PMID 1313632 DOI: 10.1007/BF00296793  0.51
1992 Dauwerse JG, Wiegant J, Raap AK, Breuning MH, Van Ommen GJB. Multiple colors by fluorescence in situ hybridization using ratio-labelled DNA probes create a molecular karyotype Human Molecular Genetics. 1: 593-598. PMID 1301168  0.381
1992 Wiegant J, Kalle W, Mullenders L, Brookes S, Hoovers JMN, Dauwerse JG, Van Ommen GJB, Raap AK. High-resolution in situ hybridization using DNA halo preparations Human Molecular Genetics. 1: 587-591. PMID 1301167 DOI: 10.1093/Hmg/1.8.587  0.347
1991 Wiegant J, Galjart NJ, Raap AK, d'Azzo A. The gene encoding human protective protein (PPGB) is on chromosome 20 Genomics. 10: 345-349. PMID 2071143 DOI: 10.1016/0888-7543(91)90318-9  0.443
1991 Wiegant J, Ried T, Nederlof PM, van der Ploeg M, Tanke HJ, Raap AK. In situ hybridization with fluoresceinated DNA. Nucleic Acids Research. 19: 3237-41. PMID 2062640 DOI: 10.1093/Nar/19.12.3237  0.727
1991 Arnoldus EP, Noordermeer IA, Peters AC, Raap AK, Van der Ploeg M. Interphase cytogenetics reveals somatic pairing of chromosome 17 centromeres in normal human brain tissue, but no trisomy 7 or sex-chromosome loss. Cytogenetics and Cell Genetics. 56: 214-6. PMID 2055120  0.612
1991 Kibbelaar RE, van Kamp H, Dreef EJ, Wessels JW, Beverstock GC, Raap AK, Fibbe WE, den Ottolander GJ, Kluin PM. Detection of trisomy 8 in hematological disorders by in situ hybridization. Cytogenetics and Cell Genetics. 56: 132-6. PMID 2055106 DOI: 10.1159/000133069  0.35
1991 Dirks RW, Van Gijlswijk RP, Vooijs MA, Smit AB, Bogerd J, van Minnen J, Raap AK, Van der Ploeg M. 3'-end fluorochromized and haptenized oligonucleotides as in situ hybridization probes for multiple, simultaneous RNA detection. Experimental Cell Research. 194: 310-5. PMID 2026182 DOI: 10.1016/0014-4827(91)90370-A  0.585
1991 Arnoldus EP, Dreef EJ, Noordermeer IA, Verheggen MM, Thierry RF, Peters AC, Cornelisse CJ, Van der Ploeg M, Raap AK. Feasibility of in situ hybridisation with chromosome specific DNA probes on paraffin wax embedded tissue. Journal of Clinical Pathology. 44: 900-4. PMID 1752979  0.626
1991 Raap AK, van de Rijke FM, Dirks RW, Sol CJ, Boom R, van der Ploeg M. Bicolor fluorescence in situ hybridization to intron and exon mRNA sequences. Experimental Cell Research. 197: 319-22. PMID 1720393 DOI: 10.1016/0014-4827(91)90439-2  0.641
1991 Boerman RH, Mitro A, Bloem BR, Arnoldus EP, Raap AK, Peters AC, van der Ploeg M. Detection of herpes simplex virus in the ependyma of experimentally infected mice. Acta Virologica. 35: 450-7. PMID 1688078  0.546
1991 Arnoldus EP, Noordermeer IA, Peters AC, Voormolen JH, Bots GT, Raap AK, van der Ploeg M. Interphase cytogenetics of brain tumors. Genes, Chromosomes & Cancer. 3: 101-7. PMID 1648958 DOI: 10.1002/Gcc.2870030204  0.663
1991 Boerman RH, Arnoldus EP, Peters AC, Bloem BR, Raap AK, van der Ploeg M. Polymerase chain reaction for early detection of HSV-DNA in cerebrospinal fluid: an experimental mouse encephalitis study. Journal of Medical Virology. 33: 83-8. PMID 1646855 DOI: 10.1002/Jmv.1890330204  0.605
1990 Nederlof PM, van der Flier S, Wiegant J, Raap AK, Tanke HJ, Ploem JS, van der Ploeg M. Multiple fluorescence in situ hybridization. Cytometry. 11: 126-31. PMID 2307053 DOI: 10.1002/Cyto.990110115  0.678
1990 Arnoldus EP, Wiegant J, Noordermeer IA, Wessels JW, Beverstock GC, Grosveld GC, van der Ploeg M, Raap AK. Detection of the Philadelphia chromosome in interphase nuclei. Cytogenetics and Cell Genetics. 54: 108-11. PMID 2265553 DOI: 10.1159/000132972  0.625
1990 Banfalvi G, Tanke H, Raap AK, Slats J, van der Ploeg M. Early replication signals in nuclei of Chinese hamster ovary cells. Histochemistry. 94: 435-40. PMID 2228739 DOI: 10.1007/Bf00266452  0.625
1990 van der Ploeg M, Raap AK, van Duijn P. [Hybrid cytochemistry; current possibilities for the detection and localization of nucleic acids in microscopic preparations]. Nederlands Tijdschrift Voor Geneeskunde. 134: 1084-9. PMID 2191226  0.699
1990 Jiwa M, Steenbergen RD, Zwaan FE, Kluin PM, Raap AK, van der Ploeg M. Three sensitive methods for the detection of cytomegalovirus in lung tissue of patients with interstitial pneumonitis. American Journal of Clinical Pathology. 93: 491-4. PMID 2157333  0.558
1990 Dirks RW, van Gijlswijk RP, Tullis RH, Smit AB, van Minnen J, van der Ploeg M, Raap AK. Simultaneous detection of different mRNA sequences coding for neuropeptide hormones by double in situ hybridization using FITC- and biotin-labeled oligonucleotides. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 38: 467-73. PMID 2108203  0.605
1989 Arnoldus EP, Peters AC, Bots GT, Raap AK, van der Ploeg M. Somatic pairing of chromosome 1 centromeres in interphase nuclei of human cerebellum. Human Genetics. 83: 231-4. PMID 2793166 DOI: 10.1007/BF00285162  0.633
1989 Dirks RW, Raap AK, Van Minnen J, Vreugdenhil E, Smit AB, Van der Ploeg M. Detection of mRNA molecules coding for neuropeptide hormones of the pond snail Lymnaea stagnalis by radioactive and non-radioactive in situ hybridization: a model study for mRNA detection. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 37: 7-14. PMID 2642295  0.596
1989 Nederlof PM, van der Flier S, Raap AK, Tanke HJ, van der Ploeg M, Kornips F, Geraedts JP. Detection of chromosome aberrations in interphase tumor nuclei by nonradioactive in situ hybridization. Cancer Genetics and Cytogenetics. 42: 87-98. PMID 2551485 DOI: 10.1016/0165-4608(89)90011-3  0.67
1989 Boerman RH, Arnoldus EP, Raap AK, Bloem BR, Verhey M, van Gemert G, Peters AC, van der Ploeg M. Polymerase chain reaction and viral culture techniques to detect HSV in small volumes of cerebrospinal fluid; an experimental mouse encephalitis study. Journal of Virological Methods. 25: 189-97. PMID 2550503 DOI: 10.1016/0166-0934(89)90032-3  0.562
1989 Jiwa NM, Raap AK, van de Rijke FM, Mulder A, Weening JJ, Zwaan FE, The TH, van der Ploeg M. Detection of cytomegalovirus antigens and DNA in tissues fixed in formaldehyde. Journal of Clinical Pathology. 42: 749-54. PMID 2547847 DOI: 10.1136/jcp.42.7.749  0.556
1989 Jiwa NM, Van Gemert GW, Raap AK, Van de Rijke FM, Mulder A, Lens PF, Salimans MM, Zwaan FE, Van Dorp W, Van der Ploeg M. Rapid detection of human cytomegalovirus DNA in peripheral blood leukocytes of viremic transplant recipients by the polymerase chain reaction. Transplantation. 48: 72-6. PMID 2546301  0.559
1989 Mullink H, Walboomers JMM, Raap AK, Meyer CJLM. Two colour DNA in situ hybridization for the detection of two viral genomes using non-radioactive probes Histochemistry. 91: 195-198. PMID 2542189 DOI: 10.1007/BF00490132  0.326
1989 Boerman RH, Arnoldus EP, Raap AK, Peters AC, ter Schegget J, van der Ploeg M. Diagnosis of progressive multifocal leucoencephalopathy by hybridisation techniques. Journal of Clinical Pathology. 42: 153-61. PMID 2537857  0.607
1989 Salimans MMM, Holsappel S, van de Rijke FM, Jiwa NM, Raap AK, Weiland HT. Rapid detection of human parvovirus B19 DNA by dot-hybridization and the polymerase chain reaction Journal of Virological Methods. 23: 19-28. PMID 2536380 DOI: 10.1016/0166-0934(89)90085-2  0.319
1989 Nederlof PM, Robinson D, Abuknesha R, Wiegant J, Hopman AHN, Tanke HJ, Raap AK. Three-color fluorescence in situ hybridization for the simultaneous detection of multiple nucleic acid sequences Cytometry. 10: 20-27. PMID 2492920 DOI: 10.1002/Cyto.990100105  0.481
1989 Nederlof P, van der Flier S, Raap A, Tanke H, van der Ploeg M, Kornips F, Geraedts J. 5 In situ hybridization for the detection of numerical chromosome aberrations Cancer Genetics and Cytogenetics. 38: 154. DOI: 10.1016/0165-4608(89)90533-5  0.348
1989 Raap AK, Hopman AHN, Van der Ploeg M. Hapten labeling of nucleic acid probes for DNA in situ hybridization Techniques in Immunocytochemistry. 1: 167-197.  0.617
1988 Hopman AH, Ramaekers FC, Raap AK, Beck JL, Devilee P, van der Ploeg M, Vooijs GP. In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors. Histochemistry. 89: 307-16. PMID 3410743 DOI: 10.1007/Bf00500631  0.665
1988 Boerman RH, Peters AC, Verheij M, Raap AK, van Ekdom LT, van Eer A, van der Ploeg M. Immunofluorescence detection of herpes simplex virus type 1 antigen in cerebrospinal fluid cells of experimentally infected mice. Journal of the Neurological Sciences. 87: 245-54. PMID 3210036 DOI: 10.1016/0022-510X(88)90249-3  0.566
1988 Raap AK, Geelen JL, van der Meer JW, van de Rijke FM, van den Boogaart P, van der Ploeg M. Non-radioactive in situ hybridization for the detection of cytomegalovirus infections. Histochemistry. 88: 367-73. PMID 2835337 DOI: 10.1007/BF00570296  0.635
1987 Kolluri R, Devilee P, Raap A, de Koning H, Cornelisse C, Pearson P. 73 Detection of numerical chromosome changes in interphase nuclei using chromosome specific repetitive probes Cancer Genetics and Cytogenetics. 28: 47. DOI: 10.1016/0165-4608(87)90352-9  0.442
1986 Hopman AH, Wiegant J, Raap AK, Landegent JE, van der Ploeg M, van Duijn P. Bi-color detection of two target DNAs by non-radioactive in situ hybridization. Histochemistry. 85: 1-4. PMID 3733470 DOI: 10.1007/BF00508646  0.764
1986 Raap AK, Marijnen JG, Vrolijk J, van der Ploeg M. Denaturation, renaturation, and loss of DNA during in situ hybridization procedures. Cytometry. 7: 235-42. PMID 3709305 DOI: 10.1002/cyto.990070303  0.597
1986 Peters ACB, Boogerd W, Pol J, van Oirschot JT, Raap AK, van der Ploeg M, Boerman RH, Verhey M. Scientific Meeting of the Amsterdamsche Neurologenvereeniging held in Amsterdam, 1st May 1986 Clinical Neurology and Neurosurgery. 88: 317-319.  0.435
1985 van der Ploeg M, van Duijn P, Bauman JG, Landegent JE, Raap AK. Hybridocytochemistry as a tool for the investigation of chromatin organization. Basic and Applied Histochemistry. 29: 181-9. PMID 3904712  0.724
1984 Raap AK, Van Duijn P. Localization mechanisms in enzyme cytochemistry studied with alkaline phosphatase-loaded erythrocyte ghosts. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 32: 815-20. PMID 6747273  0.524
1984 Van Noorden CJF, Vogels IMC, James J, Raap AK, Van Duijn P. Phenazine methosulphate in NAD(P)-dependent dehydrogenase cytochemistry The Histochemical Journal. 16: 799-803. PMID 6432744 DOI: 10.1007/BF01095284  0.486
1984 Landegent JE, Baan RA, Hoeijmakers JH, Raap AK, Van der Ploeg M. Hybridocytochemistry with 2-acetylaminofluorene-modified probes. Cell Biology International Reports. 8: 186. PMID 6327087  0.564
1984 Raap AK, Marijnen JG, van der Ploeg M. Anti-DNA.RNA sera. Specificity tests and application in quantitative in situ hybridization. Histochemistry. 81: 517-20. PMID 6084653 DOI: 10.1007/BF00489529  0.551
1983 Raap AK, Van Duijn P. Studies on the phenazine methosulphate-tetrazolium capture reaction in NAD(P)+-dependent dehydrogenase cytochemistry. II. A novel hypothesis for the mode of action of PMS and a study of the properties of reduced PMS. The Histochemical Journal. 15: 881-93. PMID 6629853 DOI: 10.1007/BF01011827  0.514
1983 Raap AK, Van Hoof GR, Van Duijn P. Studies on the phenazine methosulphate-tetrazolium salt capture reaction in NAD(P)+-dependent dehydrogenase cytochemistry. I. Localization artefacts caused by the escape of reduced co-enzyme during cytochemical reactions for NAD(P)+-dependent dehydrogenases. The Histochemical Journal. 15: 861-79. PMID 6629852 DOI: 10.1007/BF01011826  0.535
1982 Prosperi E, Raap AK, van der Ploeg M. Histochemical model studies of enzyme activity after thermal damage. Histochemistry. 75: 387-97. PMID 7141891 DOI: 10.1007/BF00496741  0.486
1982 van Prooijen-Knegt AC, Raap AK, van der Burg MJ, Vrolijk J, van der Ploeg M. Spreading and staining of human metaphase chromosomes on aminoalkylsilane-treated glass slides. The Histochemical Journal. 14: 333-44. PMID 6178716 DOI: 10.1007/BF01041225  0.592
1981 Raap AK, Van Duijn P. Enzyme-incorporated erythrocyte ghosts: a new model system for quantitative enzyme cytochemistry. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 29: 1418-24. PMID 7320497  0.521
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