Howard J Worman, M.D.
Affiliations: | Columbia University College of Physicians and Surgeons, New York, NY, United States |
Area:
Lamins, Inner nuclear membrane proteinsWebsite:
http://asp.cpmc.columbia.edu/facdb/profile_list.asp?uni=hjw14&DepAffil=MedicineGoogle:
"Howard Worman"Children
Sign in to add trainee| Jason C. Choi | grad student | Thomas Jefferson (Microtree) | |
| Qian Ye | grad student | 1992-1996 | Mount Sinai School of Medicine |
| Ji-Yeon Shin | post-doc | Columbia University Medical School (Neurotree) | |
| Antoine Muchir | post-doc | 2003-2011 | Columbia University Medical School |
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Publications
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| Wu W, Jin Q, Östlund C, et al. (2024) mTOR Inhibition Prolongs Survival and Has Beneficial Effects on Heart Function After Onset of Lamin A/C Gene Mutation Cardiomyopathy in Mice. Circulation. Heart Failure. e011110 |
| Hernandez-Ono A, Zhao YP, Murray JW, et al. (2024) Dynamic regulation of hepatic lipid metabolism by torsinA and its activators. Jci Insight |
| Hernandez-Ono A, Zhao YP, Murray JW, et al. (2023) Functional interaction of torsinA and its activators in liver lipid metabolism. Biorxiv : the Preprint Server For Biology |
| Östlund C, Hernandez-Ono A, Turk SJ, et al. (2022) Hepatocytes deficient in nuclear envelope protein lamina-associated polypeptide 1 are an ideal mammalian system to study intranuclear lipid droplets. Journal of Lipid Research. 100277 |
| Wang Y, Shilagardi K, Hsu T, et al. (2022) Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice. Proceedings of the National Academy of Sciences of the United States of America. 119 |
| Shin JY, Worman HJ. (2021) Molecular Pathology of Laminopathies. Annual Review of Pathology |
| Vignier N, Chatzifrangkeskou M, Pinton L, et al. (2021) The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies. Cell Reports. 36: 109601 |
| Kronenberg-Tenga R, Tatli M, Eibauer M, et al. (2021) A lamin A/C variant causing striated muscle disease provides insights into filament organization. Journal of Cell Science |
| Dridi H, Wu W, Reiken SR, et al. (2021) Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation. Human Molecular Genetics |
| Marcelot A, Worman HJ, Zinn-Justin S. (2020) Protein structural and mechanistic basis of progeroid laminopathies. The Febs Journal |