Minkui Luo, Ph.D. - Publications

Affiliations: 
2005 Princeton University, Princeton, NJ 
Area:
Bioorganic and Bioinorganic Chemistry

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chen S, Wiewiora RP, Meng F, Babault N, Ma A, Yu W, Qian K, Hu H, Zou H, Wang J, Fan S, Blum G, Pittella-Silva F, Beauchamp KA, Tempel W, ... ... Luo M, et al. The dynamic conformational landscape of the protein methyltransferase SETD8. Elife. 8. PMID 31081496 DOI: 10.7554/Elife.45403  0.351
2019 Chen S, Kapilashrami K, Senevirathne C, Wang Z, Wang J, Linscott JA, Luo M. Substrate-differentiated Transition States of SET7/9-catalyzed Lysine Methylation. Journal of the American Chemical Society. PMID 31034218 DOI: 10.1021/Jacs.9B02553  0.353
2019 Scheer S, Ackloo S, Medina TS, Schapira M, Li F, Ward JA, Lewis AM, Northrop JP, Richardson PL, Kaniskan HÜ, Shen Y, Liu J, Smil D, McLeod D, Zepeda-Velazquez CA, ... Luo M, et al. A chemical biology toolbox to study protein methyltransferases and epigenetic signaling. Nature Communications. 10: 19. PMID 30604761 DOI: 10.1038/S41467-018-07905-4  0.36
2018 Zhu Y, Wang L, Senevirathne C, Chen S, Silva FP, Luo M. Abstract 353: Using cancer-associated variants to dissect functions of SETD8 Cancer Research. 78: 353-353. DOI: 10.1158/1538-7445.Am2018-353  0.358
2018 Pittella F, Blum G, Zhu Y, Senevirathne C, Luo M. Abstract 352: DNA replication licensing factor MCM5 is a target for SETD8 mediated methylation Cancer Research. 78: 352-352. DOI: 10.1158/1538-7445.Am2018-352  0.353
2016 Linscott JA, Kapilashrami K, Wang Z, Senevirathne C, Bothwell IR, Blum G, Luo M. Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940912 DOI: 10.1073/Pnas.1609032114  0.388
2016 Butler KV, Ma A, Yu W, Li F, Tempel W, Babault N, Pittella-Silva F, Shao J, Wang J, Luo M, Vedadi M, Brown PJ, Arrowsmith CH, Jin J. Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase. Journal of Medicinal Chemistry. PMID 27804297 DOI: 10.1021/Acs.Jmedchem.6B01244  0.333
2016 Wu H, Zheng W, Eram MS, Vhuiyan M, Dong A, Zeng H, He H, Brown P, Frankel A, Vedadi M, Luo M, Min J. Structural basis of arginine asymmetrical dimethylation by PRMT6. The Biochemical Journal. PMID 27480107 DOI: 10.1042/Bcj20160537  0.368
2016 Warrier T, Kapilashrami K, Argyrou A, Ioerger TR, Little D, Murphy KC, Nandakumar M, Park S, Gold B, Mi J, Zhang T, Meiler E, Rees M, Somersan-Karakaya S, Porras-De Francisco E, ... ... Luo M, et al. N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27432954 DOI: 10.1073/Pnas.1606590113  0.314
2016 Su H, Guo H, Tran N, Luo M, Zhao X. High PRMT1 Expression Promotes the Progression of Acute Megakaryocytic Leukemia Via Controlling Metabolic Pathways Blood. 128: 1551-1551. DOI: 10.1182/Blood.V128.22.1551.1551  0.318
2016 Silva FP, Blum G, Senevirathne C, Luo M. Abstract 4521: Substrate profiling for SETD8 reveals novel protein targets involved in DNA replication and DNA damage response Cancer Research. 76: 4521-4521. DOI: 10.1158/1538-7445.Am2016-4521  0.393
2015 Zhang L, Tung NT, Su H, Wang R, Lu Y, Tang H, Aoyagi S, Guo A, Khodadadi-Jamayran A, Zhou D, Qian K, Hricik T, Côté J, Han X, Zhou W, ... ... Luo M, et al. Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing. Elife. 4. PMID 26575292 DOI: 10.7554/Elife.07938  0.314
2015 LaFave LM, Béguelin W, Koche R, Teater M, Spitzer B, Chramiec A, Papalexi E, Keller MD, Hricik T, Konstantinoff K, Micol JB, Durham B, Knutson SK, Campbell JE, Blum G, ... ... Luo M, et al. Loss of BAP1 function leads to EZH2-dependent transformation. Nature Medicine. PMID 26437366 DOI: 10.1038/Nm.3947  0.315
2015 Su H, Tran N, Guo H, Luo M, Zhao X. PRMT1-Mediated Methylation of DUSP4 Determines Megakaryocyte-Erythroid Lineage Choice By Regulating p38 Signaling Blood. 126: 2387-2387. DOI: 10.1182/Blood.V126.23.2387.2387  0.353
2014 Blum G, Ibáñez G, Rao X, Shum D, Radu C, Djaballah H, Rice JC, Luo M. Small-molecule inhibitors of SETD8 with cellular activity. Acs Chemical Biology. 9: 2471-8. PMID 25137013 DOI: 10.1021/Cb500515R  0.336
2014 Wang R, Zheng W, Luo M. A sensitive mass spectrum assay to characterize engineered methionine adenosyltransferases with S-alkyl methionine analogues as substrates. Analytical Biochemistry. 450: 11-9. PMID 24374249 DOI: 10.1016/J.Ab.2013.12.026  0.344
2014 Guo H, Wang R, Zheng W, Chen Y, Blum G, Deng H, Luo M. Profiling substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues. Acs Chemical Biology. 9: 476-84. PMID 24320160 DOI: 10.1021/Cb4008259  0.388
2013 Islam K, Chen Y, Wu H, Bothwell IR, Blum GJ, Zeng H, Dong A, Zheng W, Min J, Deng H, Luo M. Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Proceedings of the National Academy of Sciences of the United States of America. 110: 16778-83. PMID 24082136 DOI: 10.1073/Pnas.1216365110  0.405
2013 Wang R, Luo M. A journey toward Bioorthogonal Profiling of Protein Methylation inside living cells. Current Opinion in Chemical Biology. 17: 729-37. PMID 24035694 DOI: 10.1016/J.Cbpa.2013.08.007  0.367
2013 Blum G, Bothwell IR, Islam K, Luo M. Profiling protein methylation with cofactor analog containing terminal alkyne functionality. Current Protocols in Chemical Biology. 5: 67-88. PMID 23788324 DOI: 10.1002/9780470559277.Ch120241  0.365
2013 Blum G, Islam K, Luo M. Bioorthogonal profiling of protein methylation (BPPM) using an azido analog of S-adenosyl-L-methionine. Current Protocols in Chemical Biology. 5: 45-66. PMID 23667794 DOI: 10.1002/9780470559277.Ch120240  0.365
2013 Wang R, Islam K, Liu Y, Zheng W, Tang H, Lailler N, Blum G, Deng H, Luo M. Profiling genome-wide chromatin methylation with engineered posttranslation apparatus within living cells. Journal of the American Chemical Society. 135: 1048-56. PMID 23244065 DOI: 10.1021/Ja309412S  0.355
2013 Zhao X, Zhang L, Wang R, Trans NT, Su H, Abdel-Wahab O, Hrick T, Levine RL, Deng H, Liu Y, Zheng Y, Luo M. Arginine Methylation Of RBM15 By PRMT1 Controls Alternative Splicing Of Genes Involved In Megakaryocyte Differentiation Blood. 122: 2443-2443. DOI: 10.1182/Blood.V122.21.2443.2443  0.361
2012 Zheng W, Ibáñez G, Wu H, Blum G, Zeng H, Dong A, Li F, Hajian T, Allali-Hassani A, Amaya MF, Siarheyeva A, Yu W, Brown PJ, Schapira M, Vedadi M, ... ... Luo M, et al. Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2. Journal of the American Chemical Society. 134: 18004-14. PMID 23043551 DOI: 10.1021/Ja307060P  0.396
2012 Bothwell IR, Islam K, Chen Y, Zheng W, Blum G, Deng H, Luo M. Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation. Journal of the American Chemical Society. 134: 14905-12. PMID 22917021 DOI: 10.1021/Ja304782R  0.382
2012 Islam K, Bothwell I, Chen Y, Sengelaub C, Wang R, Deng H, Luo M. Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine. Journal of the American Chemical Society. 134: 5909-15. PMID 22404544 DOI: 10.1021/Ja2118333  0.391
2012 Ibanez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, Luo M, Djaballah H. A high throughput scintillation proximity imaging assay for protein methyltransferases. Combinatorial Chemistry & High Throughput Screening. 15: 359-71. PMID 22256970 DOI: 10.2174/138620712800194468  0.358
2012 Luo M. Current chemical biology approaches to interrogate protein methyltransferases. Acs Chemical Biology. 7: 443-63. PMID 22220966 DOI: 10.1021/Cb200519Y  0.357
2011 Wang R, Ibáñez G, Islam K, Zheng W, Blum G, Sengelaub C, Luo M. Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors. Molecular Biosystems. 7: 2970-81. PMID 21866297 DOI: 10.1039/C1Mb05230F  0.369
2011 Wang R, Zheng W, Yu H, Deng H, Luo M. Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues. Journal of the American Chemical Society. 133: 7648-51. PMID 21539310 DOI: 10.1021/Ja2006719  0.376
2011 Islam K, Zheng W, Yu H, Deng H, Luo M. Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling. Acs Chemical Biology. 6: 679-84. PMID 21495674 DOI: 10.1021/Cb2000567  0.319
2010 Ibáñez G, McBean JL, Astudillo YM, Luo M. An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases. Analytical Biochemistry. 401: 203-10. PMID 20227379 DOI: 10.1016/J.Ab.2010.03.010  0.374
2009 Zhang Y, Luo M, Schramm VL. Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases. Journal of the American Chemical Society. 131: 4685-94. PMID 19292447 DOI: 10.1021/Ja808346Y  0.321
2008 Li L, Luo M, Ghanem M, Taylor EA, Schramm VL. Second-sphere amino acids contribute to transition-state structure in bovine purine nucleoside phosphorylase. Biochemistry. 47: 2577-83. PMID 18281958 DOI: 10.1021/Bi7021365  0.315
2008 Luo M, Li L, Schramm VL. Remote mutations alter transition-state structure of human purine nucleoside phosphorylase. Biochemistry. 47: 2565-76. PMID 18281957 DOI: 10.1021/Bi702133X  0.301
2008 Luo M, Schramm VL. Transition state structure of E. coli tRNA-specific adenosine deaminase. Journal of the American Chemical Society. 130: 2649-55. PMID 18251477 DOI: 10.1021/Ja078008X  0.307
2007 Luo M, Singh V, Taylor EA, Schramm VL. Transition-state variation in human, bovine, and Plasmodium falciparum adenosine deaminases. Journal of the American Chemical Society. 129: 8008-17. PMID 17536804 DOI: 10.1021/Ja072122Y  0.31
2006 Luo M, Lin H, Fischbach MA, Liu DR, Walsh CT, Groves JT. Enzymatic tailoring of enterobactin alters membrane partitioning and iron acquisition. Acs Chemical Biology. 1: 29-32. PMID 17163637 DOI: 10.1021/Cb0500034  0.457
2005 Luo M, Fadeev EA, Groves JT. Mycobactin-mediated iron acquisition within macrophages. Nature Chemical Biology. 1: 149-53. PMID 16408019 DOI: 10.1038/Nchembio717  0.449
2005 Fadeev EA, Luo M, Groves JT. Synthesis and structural modeling of the amphiphilic siderophore rhizobactin-1021 and its analogs. Bioorganic & Medicinal Chemistry Letters. 15: 3771-4. PMID 15990296 DOI: 10.1016/J.Bmcl.2005.05.114  0.472
2005 Luo M, Fadeev EA, Groves JT. Membrane dynamics of the amphiphilic siderophore, acinetoferrin. Journal of the American Chemical Society. 127: 1726-36. PMID 15701007 DOI: 10.1021/Ja044230F  0.457
2004 Fadeev EA, Luo M, Groves JT. Synthesis, structure, and molecular dynamics of gallium complexes of schizokinen and the amphiphilic siderophore acinetoferrin. Journal of the American Chemical Society. 126: 12065-75. PMID 15382941 DOI: 10.1021/Ja048145J  0.476
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