| Year |
Citation |
Score |
| 2020 |
Chaplot K, Jarvela TS, Lindberg I. Secreted Chaperones in Neurodegeneration. Frontiers in Aging Neuroscience. 12: 268. PMID 33192447 DOI: 10.3389/Fnagi.2020.00268 |
0.356 |
|
| 2020 |
Shakya M, Yildirim T, Lindberg I. Increased expression and retention of the secretory chaperone proSAAS following cell stress. Cell Stress & Chaperones. PMID 32607937 DOI: 10.1007/S12192-020-01128-7 |
0.332 |
|
| 2020 |
Pedrero-Prieto CM, García-Carpintero S, Frontiñán-Rubio J, Llanos-González E, Aguilera García C, Alcaín FJ, Lindberg I, Durán-Prado M, Peinado JR, Rabanal-Ruiz Y. A comprehensive systematic review of CSF proteins and peptides that define Alzheimer's disease. Clinical Proteomics. 17: 21. PMID 32518535 DOI: 10.1186/S12014-020-09276-9 |
0.32 |
|
| 2020 |
Kono T, Iida H, Jarvela TS, Lee C, Tong X, Arvan P, Lindberg I, Evans-Molina C. 48-OR: Pancreatic ß Cell SERCA2 Deficiency Leads to Impaired Proinsulin Processing and Reduced ER to Golgi Protein Trafficking Diabetes. 69. DOI: 10.2337/Db20-48-Or |
0.379 |
|
| 2020 |
Shakya M, Gahlot S, Arunagiri A, Hassan A, Arvan P, Low MJ, Lindberg I. SUN-669 The G209R Mutant Mouse as a Model for Human PCSK1 Polyendocrinopathy Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.913 |
0.393 |
|
| 2019 |
Jarvela TS, Gahlot S, Shakya M, Bachor T, White A, Low MJ, Lindberg I. Reduced stability and pH-dependent activity of a common obesity-linked PCSK1 polymorphism, N221D. Endocrinology. PMID 31504391 DOI: 10.1210/En.2019-00418 |
0.375 |
|
| 2019 |
Lam van TV, Ivanova T, Hardes K, Heindl MR, Morty RE, Böttcher-Friebertshäuser E, Lindberg I, Than ME, Dahms SO, Steinmetzer T. Design, synthesis and characterization of new macrocyclic inhibitors of the proprotein convertase furin. Chemmedchem. PMID 30680958 DOI: 10.2210/Pdb6Hzd/Pdb |
0.308 |
|
| 2019 |
Iida H, Kono T, Tong X, Lindberg I, Evans-Molina C. 341-LB: Chronic ER Calcium Depletion Resulting from Sarcoendoplasmic Reticulum Ca2+ Atpase 2b (SERCA2b) Deficiency Leads to Impaired Proinsulin Processing in the Pancreatic ß Cell Diabetes. 68. DOI: 10.2337/Db19-341-Lb |
0.349 |
|
| 2018 |
Jarvela TS, Womack T, Georgiou P, Gould TD, Eriksen JL, Lindberg I. 7B2 chaperone knockout in APP model mice results in reduced plaque burden. Scientific Reports. 8: 9813. PMID 29955078 DOI: 10.1038/S41598-018-28031-7 |
0.358 |
|
| 2017 |
Ivanova T, Hardes K, Kallis S, Dahms SO, Than ME, Künzel S, Böttcher-Friebertshäuser E, Lindberg I, Jiao GS, Bartenschlager R, Steinmetzer T. Optimization of substrate-analog furin inhibitors. Chemmedchem. PMID 29059503 DOI: 10.1002/Cmdc.201700596 |
0.342 |
|
| 2017 |
Katorcha E, Makarava N, Lee YJ, Lindberg I, Monteiro MJ, Kovacs GG, Baskakov IV. Cross-seeding of prions by aggregated α-synuclein leads to transmissible spongiform encephalopathy. Plos Pathogens. 13: e1006563. PMID 28797122 DOI: 10.1371/Journal.Ppat.1006563 |
0.327 |
|
| 2017 |
Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T. Elongated and shortened peptidomimetic inhibitors of the proprotein convertase furin. Chemmedchem. PMID 28334511 DOI: 10.1002/Cmdc.201700108 |
0.34 |
|
| 2016 |
Ramos-Molina B, Martin MG, Lindberg I. PCSK1 Variants and Human Obesity. Progress in Molecular Biology and Translational Science. 140: 47-74. PMID 27288825 DOI: 10.1016/Bs.Pmbts.2015.12.001 |
0.356 |
|
| 2016 |
Yamamoto H, Ramos-Molina B, Lick AN, Prideaux M, Albornoz V, Bonewald L, Lindberg I. Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition. Bone. 84: 120-30. PMID 26746780 DOI: 10.1016/J.Bone.2015.12.055 |
0.379 |
|
| 2015 |
Lindberg I, Shorter J, Wiseman RL, Chiti F, Dickey CA, McLean PJ. Chaperones in Neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13853-9. PMID 26468185 DOI: 10.1523/Jneurosci.2600-15.2015 |
0.307 |
|
| 2015 |
Blanco EH, Ramos-Molina B, Lindberg I. Revisiting PC1/3 Mutants: Dominant-Negative Effect of Endoplasmic Reticulum-Retained Mutants. Endocrinology. 156: 3625-37. PMID 26207343 DOI: 10.1210/En.2015-1068 |
0.394 |
|
| 2015 |
Ramos-Molina B, Lick AN, Nasrolahi Shirazi A, Oh D, Tiwari R, El-Sayed NS, Parang K, Lindberg I. Cationic Cell-Penetrating Peptides Are Potent Furin Inhibitors. Plos One. 10: e0130417. PMID 26110264 DOI: 10.1371/Journal.Pone.0130417 |
0.419 |
|
| 2015 |
Ramos-Molina B, Lick AN, Blanco EH, Posada-Salgado JA, Martinez-Mayorga K, Johnson AT, Jiao GS, Lindberg I. Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays. Biochemical Pharmacology. 96: 107-18. PMID 26003844 DOI: 10.1016/J.Bcp.2015.05.008 |
0.34 |
|
| 2015 |
Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T. Novel Furin Inhibitors with Potent Anti-infectious Activity. Chemmedchem. 10: 1218-31. PMID 25974265 DOI: 10.1002/Cmdc.201500103 |
0.339 |
|
| 2015 |
Ramos-Molina B, Lindberg I. Phosphorylation and Alternative Splicing of 7B2 Reduce Prohormone Convertase 2 Activation. Molecular Endocrinology (Baltimore, Md.). 29: 756-64. PMID 25811241 DOI: 10.1210/Me.2014-1394 |
0.383 |
|
| 2015 |
Lindberg I, Pang HW, Stains JP, Clark D, Yang AJ, Bonewald L, Li KZ. FGF23 is endogenously phosphorylated in bone cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 449-54. PMID 25195776 DOI: 10.1002/Jbmr.2354 |
0.316 |
|
| 2014 |
Wilschanski M, Abbasi M, Blanco E, Lindberg I, Yourshaw M, Zangen D, Berger I, Shteyer E, Pappo O, Bar-Oz B, Martín MG, Elpeleg O. A novel familial mutation in the PCSK1 gene that alters the oxyanion hole residue of proprotein convertase 1/3 and impairs its enzymatic activity. Plos One. 9: e108878. PMID 25272002 DOI: 10.1371/Journal.Pone.0108878 |
0.374 |
|
| 2014 |
Blanco EH, Peinado JR, Martín MG, Lindberg I. Biochemical and cell biological properties of the human prohormone convertase 1/3 Ser357Gly mutation: a PC1/3 hypermorph. Endocrinology. 155: 3434-47. PMID 24932808 DOI: 10.1210/En.2013-2151 |
0.486 |
|
| 2014 |
Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, et al. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E2319-28. PMID 24843127 DOI: 10.1073/Pnas.1323066111 |
0.307 |
|
| 2014 |
Prabhu Y, Blanco EH, Liu M, Peinado JR, Wheeler MC, Gekakis N, Arvan P, Lindberg I. Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function. Endocrinology. 155: 2391-401. PMID 24828610 DOI: 10.1210/En.2013-1985 |
0.39 |
|
| 2014 |
Hoshino A, Helwig M, Rezaei S, Berridge C, Eriksen JL, Lindberg I. A novel function for proSAAS as an amyloid anti-aggregant in Alzheimer's disease. Journal of Neurochemistry. 128: 419-30. PMID 24102330 DOI: 10.1111/Jnc.12454 |
0.554 |
|
| 2013 |
Yourshaw M, Solorzano-Vargas RS, Pickett LA, Lindberg I, Wang J, Cortina G, Pawlikowska-Haddal A, Baron H, Venick RS, Nelson SF, MartÃn MG. Exome sequencing finds a novel PCSK1 mutation in a child with generalized malabsorptive diarrhea and diabetes insipidus. Journal of Pediatric Gastroenterology and Nutrition. 57: 759-67. PMID 24280991 DOI: 10.1097/Mpg.0B013E3182A8Ae6C |
0.325 |
|
| 2013 |
Peinado JR, Sami F, Rajpurohit N, Lindberg I. Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS. Febs Letters. 587: 3406-11. PMID 24042052 DOI: 10.1016/J.Febslet.2013.09.006 |
0.396 |
|
| 2013 |
MartÃn MG, Lindberg I, Solorzano-Vargas RS, Wang J, Avitzur Y, Bandsma R, Sokollik C, Lawrence S, Pickett LA, Chen Z, Egritas O, Dalgic B, Albornoz V, de Ridder L, Hulst J, et al. Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathies in a pediatric cohort. Gastroenterology. 145: 138-48. PMID 23562752 DOI: 10.1053/J.Gastro.2013.03.048 |
0.346 |
|
| 2013 |
Yongye AB, Vivoli M, Lindberg I, Appel JR, Houghten RA, Martinez-Mayorga K. Identification of a small molecule that selectively inhibits mouse PC2 over mouse PC1/3: a computational and experimental study. Plos One. 8: e56957. PMID 23451118 DOI: 10.1371/Journal.Pone.0056957 |
0.374 |
|
| 2013 |
Helwig M, Hoshino A, Berridge C, Lee SN, Lorenzen N, Otzen DE, Eriksen JL, Lindberg I. The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins. The Journal of Biological Chemistry. 288: 1114-24. PMID 23172224 DOI: 10.1074/Jbc.M112.417071 |
0.579 |
|
| 2013 |
Yuan B, Feng JQ, Bowman S, Liu Y, Blank RD, Lindberg I, Drezner MK. Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 56-72. PMID 22886699 DOI: 10.1002/Jbmr.1738 |
0.387 |
|
| 2012 |
Dasgupta I, Sanglas L, Enghild JJ, Lindberg I. The neuroendocrine protein 7B2 is intrinsically disordered. Biochemistry. 51: 7456-64. PMID 22947085 DOI: 10.1021/Bi300871K |
0.379 |
|
| 2012 |
Becker GL, Lu Y, Hardes K, Strehlow B, Levesque C, Lindberg I, Sandvig K, Bakowsky U, Day R, Garten W, Steinmetzer T. Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases. The Journal of Biological Chemistry. 287: 21992-2003. PMID 22539349 DOI: 10.1074/Jbc.M111.332643 |
0.377 |
|
| 2012 |
Vivoli M, Caulfield TR, Martínez-Mayorga K, Johnson AT, Jiao GS, Lindberg I. Inhibition of prohormone convertases PC1/3 and PC2 by 2,5-dideoxystreptamine derivatives. Molecular Pharmacology. 81: 440-54. PMID 22169851 DOI: 10.1124/Mol.111.077040 |
0.434 |
|
| 2012 |
Toll L, Khroyan TV, Sonmez K, Ozawa A, Lindberg I, McLaughlin JP, Eans SO, Shahien AA, Kapusta DR. Peptides derived from the prohormone proNPQ/spexin are potent central modulators of cardiovascular and renal function and nociception. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 947-54. PMID 22038051 DOI: 10.1096/Fj.11-192831 |
0.347 |
|
| 2012 |
Declercq J, Zhu J, Lindberg I, Ghassabeh GH, Meulemans S, Vermorken AJM, Ven WJMVd, Muyldermans S, Creemers JWM. Abstract 4627: Generation and characterization of non-competitive furin-inhibiting nanobodies Cancer Research. 72: 4627-4627. DOI: 10.1158/1538-7445.Am2012-4627 |
0.427 |
|
| 2011 |
Helwig M, Lee SN, Hwang JR, Ozawa A, Medrano JF, Lindberg I. Dynamic modulation of prohormone convertase 2 (PC2)-mediated precursor processing by 7B2 protein: preferential effect on glucagon synthesis. The Journal of Biological Chemistry. 286: 42504-13. PMID 22013069 DOI: 10.1074/Jbc.M111.281980 |
0.471 |
|
| 2011 |
Kuester M, Becker GL, Hardes K, Lindberg I, Steinmetzer T, Than ME. Purification of the proprotein convertase furin by affinity chromatography based on PC-specific inhibitors. Biological Chemistry. 392: 973-81. PMID 21875402 DOI: 10.1515/Bc.2011.100 |
0.436 |
|
| 2011 |
Lindberg I, Appel JR. Inhibitor screening of proprotein convertases using positional scanning libraries. Methods in Molecular Biology (Clifton, N.J.). 768: 155-66. PMID 21805241 DOI: 10.1007/978-1-61779-204-5_7 |
0.335 |
|
| 2011 |
Helwig M, Vivoli M, Fricker LD, Lindberg I. Regulation of neuropeptide processing enzymes by catecholamines in endocrine cells. Molecular Pharmacology. 80: 304-13. PMID 21540292 DOI: 10.1124/Mol.111.072090 |
0.457 |
|
| 2011 |
Ozawa A, Lick AN, Lindberg I. Processing of proaugurin is required to suppress proliferation of tumor cell lines. Molecular Endocrinology (Baltimore, Md.). 25: 776-84. PMID 21436262 DOI: 10.1210/Me.2010-0389 |
0.437 |
|
| 2011 |
Hoshino A, Kowalska D, Jean F, Lazure C, Lindberg I. Modulation of PC1/3 activity by self-interaction and substrate binding. Endocrinology. 152: 1402-11. PMID 21303942 DOI: 10.1210/En.2010-1170 |
0.666 |
|
| 2010 |
Izidoro MA, Assis DM, Oliveira V, Santos JA, Juliano MA, Lindberg I, Juliano L. Effects of magnesium ions on recombinant human furin: selective activation of hydrolytic activity upon substrates derived from virus envelope glycoprotein. Biological Chemistry. 391: 1105-12. PMID 20635860 DOI: 10.1515/Bc.2010.114 |
0.307 |
|
| 2010 |
Ozawa A, Peinado JR, Lindberg I. Modulation of prohormone convertase 1/3 properties using site-directed mutagenesis. Endocrinology. 151: 4437-45. PMID 20610561 DOI: 10.1210/En.2010-0296 |
0.455 |
|
| 2010 |
Ozawa A, Lindberg I, Roth B, Kroeze WK. Deorphanization of novel peptides and their receptors. The Aaps Journal. 12: 378-84. PMID 20446073 DOI: 10.1208/S12248-010-9198-9 |
0.373 |
|
| 2010 |
Becker GL, Sielaff F, Than ME, Lindberg I, Routhier S, Day R, Lu Y, Garten W, Steinmetzer T. Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics. Journal of Medicinal Chemistry. 53: 1067-75. PMID 20038105 DOI: 10.1021/Jm9012455 |
0.425 |
|
| 2009 |
Izidoro MA, Gouvea IE, Santos JA, Assis DM, Oliveira V, Judice WA, Juliano MA, Lindberg I, Juliano L. A study of human furin specificity using synthetic peptides derived from natural substrates, and effects of potassium ions. Archives of Biochemistry and Biophysics. 487: 105-14. PMID 19477160 DOI: 10.1016/J.Abb.2009.05.013 |
0.347 |
|
| 2009 |
Ozawa A, Speaker RB, Lindberg I. Enzymatic characterization of a human acyltransferase activity. Plos One. 4: e5426. PMID 19412546 DOI: 10.1371/Journal.Pone.0005426 |
0.426 |
|
| 2009 |
Kowalska D, Liu J, Appel JR, Ozawa A, Nefzi A, Mackin RB, Houghten RA, Lindberg I. Synthetic small-molecule prohormone convertase 2 inhibitors. Molecular Pharmacology. 75: 617-25. PMID 19074544 DOI: 10.1124/Mol.108.051334 |
0.427 |
|
| 2009 |
Kudo H, Liu J, Jansen EJR, Ozawa A, Panula P, Martens GJM, Lindberg I. Identification of proSAAS homologs in lower vertebrates: conservation of hydrophobic helices and convertase-inhibiting sequences. Endocrinology. 150: 1393-1399. PMID 18948394 DOI: 10.1210/En.2008-1301 |
0.396 |
|
| 2008 |
Lee SN, Lindberg I. 7B2 prevents unfolding and aggregation of prohormone convertase 2. Endocrinology. 149: 4116-27. PMID 18467442 DOI: 10.1210/En.2008-0064 |
0.442 |
|
| 2008 |
Hwang JR, Lindberg I. Inactivation of the 7B2 inhibitory CT peptide depends on a functional furin cleavage site. Journal of Neurochemistry. 79: 437-444. PMID 11677272 DOI: 10.1046/J.1471-4159.2001.00594.X |
0.46 |
|
| 2007 |
Ozawa A, Cai Y, Lindberg I. Production of bioactive peptides in an in vitro system. Analytical Biochemistry. 366: 182-9. PMID 17540328 DOI: 10.1016/J.Ab.2007.04.020 |
0.425 |
|
| 2007 |
Lee SN, Peng B, Desjardins R, Pintar JE, Day R, Lindberg I. Strain-specific steroidal control of pituitary function. The Journal of Endocrinology. 192: 515-25. PMID 17332521 DOI: 10.1677/Joe-06-0145 |
0.323 |
|
| 2007 |
Lee SN, Kacprzak MM, Day R, Lindberg I. Processing and trafficking of a prohormone convertase 2 active site mutant. Biochemical and Biophysical Research Communications. 355: 825-9. PMID 17320043 DOI: 10.1016/J.Bbrc.2007.02.034 |
0.417 |
|
| 2007 |
Fugere M, Appel J, Houghten RA, Lindberg I, Day R. Short polybasic peptide sequences are potent inhibitors of PC5/6 and PC7: Use of positional scanning-synthetic peptide combinatorial libraries as a tool for the optimization of inhibitory sequences. Molecular Pharmacology. 71: 323-32. PMID 17012622 DOI: 10.1124/Mol.106.027946 |
0.444 |
|
| 2006 |
Lee SN, Hwang JR, Lindberg I. Neuroendocrine protein 7B2 can be inactivated by phosphorylation within the secretory pathway. The Journal of Biological Chemistry. 281: 3312-20. PMID 16286464 DOI: 10.1074/Jbc.M506635200 |
0.437 |
|
| 2006 |
Shiryaev SA, Ratnikov BI, Chekanov AV, Sikora S, Rozanov DV, Godzik A, Wang J, Smith JW, Huang Z, Lindberg I, Samuel MA, Diamond MS, Strongin AY. Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase. The Biochemical Journal. 393: 503-11. PMID 16229682 DOI: 10.1042/Bj20051374 |
0.408 |
|
| 2005 |
Kacprzak MM, Than ME, Juliano L, Juliano MA, Bode W, Lindberg I. Mutations of the PC2 substrate binding pocket alter enzyme specificity. The Journal of Biological Chemistry. 280: 31850-8. PMID 16002408 DOI: 10.1074/Jbc.M505567200 |
0.399 |
|
| 2005 |
Peinado JR, Laurent V, Lee SN, Peng BW, Pintar JE, Steiner DF, Lindberg I. Strain-dependent influences on the hypothalamo-pituitary-adrenal axis profoundly affect the 7B2 and PC2 null phenotypes. Endocrinology. 146: 3438-44. PMID 15878971 DOI: 10.1210/En.2004-1289 |
0.357 |
|
| 2005 |
Henrich S, Lindberg I, Bode W, Than ME. Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity. Journal of Molecular Biology. 345: 211-27. PMID 15571716 DOI: 10.1016/J.Jmb.2004.10.050 |
0.372 |
|
| 2004 |
Peinado JR, Kacprzak MM, Leppla SH, Lindberg I. Cross-inhibition between furin and lethal factor inhibitors. Biochemical and Biophysical Research Communications. 321: 601-5. PMID 15358148 DOI: 10.1016/J.Bbrc.2004.07.012 |
0.379 |
|
| 2004 |
Lee SN, Prodhomme E, Lindberg I. Prohormone convertase 1 (PC1) processing and sorting: effect of PC1 propeptide and proSAAS. The Journal of Endocrinology. 182: 353-64. PMID 15283695 DOI: 10.1677/Joe.0.1820353 |
0.439 |
|
| 2004 |
Kacprzak MM, Peinado JR, Than ME, Appel J, Henrich S, Lipkind G, Houghten RA, Bode W, Lindberg I. Inhibition of furin by polyarginine-containing peptides: nanomolar inhibition by nona-D-arginine. The Journal of Biological Chemistry. 279: 36788-94. PMID 15197180 DOI: 10.1074/Jbc.M400484200 |
0.405 |
|
| 2004 |
Sarac MS, Peinado JR, Leppla SH, Lindberg I. Protection against anthrax toxemia by hexa-D-arginine in vitro and in vivo. Infection and Immunity. 72: 602-5. PMID 14688144 DOI: 10.1128/Iai.72.1.602-605.2004 |
0.335 |
|
| 2004 |
Laurent V, Jaubert-Miazza L, Desjardins R, Day R, Lindberg I. Biosynthesis of proopiomelanocortin-derived peptides in prohormone convertase 2 and 7B2 null mice. Endocrinology. 145: 519-28. PMID 14576186 DOI: 10.1210/En.2003-0829 |
0.462 |
|
| 2003 |
Peinado JR, Li H, Johanning K, Lindberg I. Cleavage of recombinant proenkephalin and blockade mutants by prohormone convertases 1 and 2: an in vitro specificity study. Journal of Neurochemistry. 87: 868-78. PMID 14622118 DOI: 10.1046/J.1471-4159.2003.02043.X |
0.465 |
|
| 2003 |
Winsky-Sommerer R, Grouselle D, Rougeot C, Laurent V, David JP, Delacourte A, Dournaud P, Seidah NG, Lindberg I, Trottier S, Epelbaum J. The proprotein convertase PC2 is involved in the maturation of prosomatostatin to somatostatin-14 but not in the somatostatin deficit in Alzheimer's disease. Neuroscience. 122: 437-47. PMID 14614908 DOI: 10.1016/S0306-4522(03)00560-8 |
0.396 |
|
| 2003 |
Henrich S, Cameron A, Bourenkov GP, Kiefersauer R, Huber R, Lindberg I, Bode W, Than ME. The crystal structure of the proprotein processing proteinase furin explains its stringent specificity. Nature Structural Biology. 10: 520-6. PMID 12794637 DOI: 10.1038/Nsb941 |
0.349 |
|
| 2003 |
Cornwall GA, Cameron A, Lindberg I, Hardy DM, Cormier N, Hsia N. The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2. Endocrinology. 144: 901-8. PMID 12586766 DOI: 10.1210/En.2002-220997 |
0.413 |
|
| 2003 |
Li QL, Naqvi S, Shen X, Liu YJ, Lindberg I, Friedman TC. Prohormone convertase 2 enzymatic activity and its regulation in neuro-endocrine cells and tissues. Regulatory Peptides. 110: 197-205. PMID 12573800 DOI: 10.1016/S0167-0115(02)00207-0 |
0.455 |
|
| 2002 |
Rehfeld JF, Lindberg I, Friis-Hansen L. Increased synthesis but decreased processing of neuronal proCCK in prohormone convertase 2 and 7B2 knockout animals. Journal of Neurochemistry. 83: 1329-37. PMID 12472887 DOI: 10.1046/J.1471-4159.2002.01244.X |
0.459 |
|
| 2002 |
Sarac MS, Cameron A, Lindberg I. The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. Infection and Immunity. 70: 7136-9. PMID 12438396 DOI: 10.1128/Iai.70.12.7136-7139.2002 |
0.311 |
|
| 2002 |
Laslop A, Becker A, Lindberg I, Fischer-Colbrie R. Proteolytic processing of chromogranins is modified in brains of transgenic mice. Annals of the New York Academy of Sciences. 971: 49-52. PMID 12438088 DOI: 10.1111/J.1749-6632.2002.Tb04432.X |
0.386 |
|
| 2002 |
Zhu X, Zhou A, Dey A, Norrbom C, Carroll R, Zhang C, Laurent V, Lindberg I, Ugleholdt R, Holst JJ, Steiner DF. Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. Proceedings of the National Academy of Sciences of the United States of America. 99: 10293-8. PMID 12145326 DOI: 10.1073/Pnas.162352599 |
0.386 |
|
| 2002 |
Sarac MS, Zieske AW, Lindberg I. The lethal form of Cushing's in 7B2 null mice is caused by multiple metabolic and hormonal abnormalities. Endocrinology. 143: 2324-32. PMID 12021197 DOI: 10.1210/Endo.143.6.8808 |
0.367 |
|
| 2002 |
Sarac MS, Windeatt S, Castro MG, Lindberg I. Intrapituitary adenoviral administration of 7B2 can extend life span and reverse endocrinological deficiencies in 7B2 null mice. Endocrinology. 143: 2314-23. PMID 12021196 DOI: 10.1210/Endo.143.6.8811 |
0.37 |
|
| 2002 |
Laurent V, Kimble A, Peng B, Zhu P, Pintar JE, Steiner DF, Lindberg I. Mortality in 7B2 null mice can be rescued by adrenalectomy: involvement of dopamine in ACTH hypersecretion. Proceedings of the National Academy of Sciences of the United States of America. 99: 3087-92. PMID 11854475 DOI: 10.1073/Pnas.261715099 |
0.409 |
|
| 2002 |
Rehfeld JF, Lindberg I, Friis-Hansen L. Progastrin processing differs in 7B2 and PC2 knockout animals: a role for 7B2 independent of action on PC2. Febs Letters. 510: 89-93. PMID 11755537 DOI: 10.1016/S0014-5793(01)03234-3 |
0.428 |
|
| 2002 |
Fortenberry Y, Hwang JR, Apletalina EV, Lindberg I. Functional characterization of ProSAAS: similarities and differences with 7B2. The Journal of Biological Chemistry. 277: 5175-86. PMID 11719503 DOI: 10.1074/Jbc.M104531200 |
0.522 |
|
| 2002 |
Cameron A, Apletalina EV, Lindberg I. 11 – The Enzymology of PC1 and PC2 The Enzymes. 22: 291-332. DOI: 10.1016/S1874-6047(02)80012-9 |
0.335 |
|
| 2001 |
Zachariah C, Cameron A, Lindberg I, Kao KJ, Beinfeld MC, Edison AS. Structural studies of a neuropeptide precursor protein with an RGD proteolytic site Biochemistry. 40: 8790-8799. PMID 11467939 DOI: 10.1021/Bi010448S |
0.437 |
|
| 2001 |
Sayah M, Fortenberry Y, Cameron A, Lindberg I. Tissue distribution and processing of proSAAS by proprotein convertases Journal of Neurochemistry. 76: 1833-1841. PMID 11259501 DOI: 10.1046/J.1471-4159.2001.00165.X |
0.48 |
|
| 2001 |
Fortenberry Y, Liu J, Lindberg I. The role of the 7B2 CT peptide in the inhibition of prohormone convertase 2 in endocrine cell lines. Journal of Neurochemistry. 73: 994-1003. PMID 10461888 DOI: 10.1046/J.1471-4159.1999.0730994.X |
0.474 |
|
| 2000 |
Muller L, Cameron A, Fortenberry Y, Apletalina EV, Lindberg I. Processing and Sorting of the Prohormone Convertase 2 Propeptide Journal of Biological Chemistry. 275: 39213-39222. PMID 10995742 DOI: 10.1074/Jbc.M003547200 |
0.423 |
|
| 2000 |
Cameron A, Appel J, Houghten RA, Lindberg I. Polyarginines are potent furin inhibitors. The Journal of Biological Chemistry. 275: 36741-9. PMID 10958789 DOI: 10.1074/Jbc.M003848200 |
0.4 |
|
| 2000 |
Cameron A, Fortenberry YM, Lindberg I. The SAAS granin exhibits structural and functional homology to 7B2 and contains a highly potent hexapeptide inhibitor of PC1. Febs Letters. 473: 135-138. PMID 10812060 DOI: 10.1016/S0014-5793(00)01511-8 |
0.478 |
|
| 2000 |
Apletalina EV, Muller L, Lindberg I. Mutations in the Catalytic Domain of Prohormone Convertase 2 Result in Decreased Binding to 7B2 and Loss of Inhibition with 7B2 C-terminal Peptide Journal of Biological Chemistry. 275: 14667-14677. PMID 10799554 DOI: 10.1074/Jbc.275.19.14667 |
0.491 |
|
| 2000 |
Hwang JR, Siekhaus DE, Fuller RS, Taghert PH, Lindberg I. Interaction of Drosophila melanogaster prohormone convertase 2 and 7B2. Insect cell-specific processing and secretion. The Journal of Biological Chemistry. 275: 17886-93. PMID 10749852 DOI: 10.1074/Jbc.M000032200 |
0.466 |
|
| 2000 |
Apletalina EV, Juliano MA, Juliano L, Lindberg I. Structure-function analysis of the 7B2 CT peptide. Biochemical and Biophysical Research Communications. 267: 940-2. PMID 10673395 DOI: 10.1006/Bbrc.1999.2060 |
0.416 |
|
| 1999 |
Muller L, Lindberg I. The cell biology of the prohormone convertases PC1 and PC2. Progress in Nucleic Acid Research and Molecular Biology. 63: 69-108. PMID 10506829 DOI: 10.1016/S0079-6603(08)60720-5 |
0.493 |
|
| 1999 |
Muller L, Zhu P, Juliano MA, Juliano L, Lindberg I. A 36-residue peptide contains all of the information required for 7B2-mediated activation of prohormone convertase 2. The Journal of Biological Chemistry. 274: 21471-7. PMID 10409712 DOI: 10.1074/Jbc.274.30.21471 |
0.457 |
|
| 1999 |
Westphal CH, Muller L, Zhou A, Zhu X, Bonner-Weir S, Schambelan M, Steiner DF, Lindberg I, Leder P. The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease. Cell. 96: 689-700. PMID 10089884 DOI: 10.1016/S0092-8674(00)80579-6 |
0.444 |
|
| 1999 |
Lamango NS, Apletalina E, Liu J, Lindberg I. The Proteolytic Maturation of Prohormone Convertase 2 (PC2) is a pH-Driven Process Archives of Biochemistry and Biophysics. 362: 275-282. PMID 9989936 DOI: 10.1006/Abbi.1998.1033 |
0.459 |
|
| 1998 |
Apletalina E, Appel J, Lamango NS, Houghten RA, Lindberg I. Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library. The Journal of Biological Chemistry. 273: 26589-95. PMID 9756897 DOI: 10.1074/jbc.273.41.26589 |
0.334 |
|
| 1998 |
Lindberg I, Tu B, Muller L, Dickerson IM. Cloning and functional analysis of C. elegans 7B2. Dna and Cell Biology. 17: 727-34. PMID 9726255 DOI: 10.1089/Dna.1998.17.727 |
0.441 |
|
| 1998 |
Johanning K, Juliano MA, Juliano L, Lazure C, Lamango NS, Steiner DF, Lindberg I. Specificity of prohormone convertase 2 on proenkephalin and proenkephalin-related substrates. The Journal of Biological Chemistry. 273: 22672-80. PMID 9712897 DOI: 10.1074/Jbc.273.35.22672 |
0.428 |
|
| 1998 |
Day R, Lazure C, Basak A, Boudreault A, Limperis P, Dong W, Lindberg I. Prodynorphin Processing by Proprotein Convertase 2 CLEAVAGE AT SINGLE BASIC RESIDUES AND ENHANCED PROCESSING IN THE PRESENCE OF CARBOXYPEPTIDASE ACTIVITY Journal of Biological Chemistry. 273: 829-836. PMID 9422738 DOI: 10.1074/Jbc.273.2.829 |
0.483 |
|
| 1997 |
Muller L, Zhu X, Lindberg I. Mechanism of the Facilitation of PC2 Maturation by 7B2: Involvement in ProPC2 Transport and Activation but Not Folding Journal of Cell Biology. 139: 625-638. PMID 9348280 DOI: 10.1083/Jcb.139.3.625 |
0.389 |
|
| 1996 |
Johanning K, Mathis JP, Lindberg I. Processing site blockade results in more efficient conversion of proenkephalin to active opioid peptides. The Journal of Biological Chemistry. 271: 27871-8. PMID 8910386 DOI: 10.1074/Jbc.271.44.27871 |
0.348 |
|
| 1996 |
Zhu X, Lamango NS, Lindberg I. Involvement of a Polyproline Helix-like Structure in the Interaction of 7B2 with Prohormone Convertase 2* Journal of Biological Chemistry. 271: 23582-23587. PMID 8798569 DOI: 10.1074/Jbc.271.38.23582 |
0.433 |
|
| 1996 |
Johanning K, Mathis JP, Lindberg I. Role of PC2 in proenkephalin processing: antisense and overexpression studies. Journal of Neurochemistry. 66: 898-907. PMID 8769847 DOI: 10.1046/J.1471-4159.1996.66030898.X |
0.443 |
|
| 1996 |
Lamango NS, Zhu X, Lindberg I. Purification and Enzymatic Characterization of Recombinant Prohormone Convertase 2: Stabilization of Activity by 21 kDa 7B2 Archives of Biochemistry and Biophysics. 330: 238-250. PMID 8660652 DOI: 10.1006/Abbi.1996.0249 |
0.466 |
|
| 1996 |
Zhu X, Rouille Y, Lamango NS, Steiner DF, Lindberg I. Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: A potential mechanism for its inactivation Proceedings of the National Academy of Sciences of the United States of America. 93: 4919-4924. PMID 8643504 DOI: 10.1073/Pnas.93.10.4919 |
0.428 |
|
| 1995 |
Zhu X, Lindberg I. 7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity. Journal of Cell Biology. 129: 1641-1650. PMID 7790360 DOI: 10.1083/Jcb.129.6.1641 |
0.471 |
|
| 1995 |
Horssen AMV, Wilhelmina HVdH, Bailyes EM, Hutton JC, Martens GJM, Lindberg I. Identification Of The Region Within The Neuroendocrine Polypeptide 7B2 Responsible For The Inhibition Of Prohormone Convertase Pc2 Journal of Biological Chemistry. 270: 14292-14296. PMID 7782286 DOI: 10.1074/Jbc.270.24.14292 |
0.468 |
|
| 1995 |
Rothenberg ME, Eilertson CD, Klein K, Zhou Y, Lindberg I, McDonald JK, Mackin RB, Noe BD. Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro. The Journal of Biological Chemistry. 270: 10136-46. PMID 7730317 DOI: 10.1074/Jbc.270.17.10136 |
0.472 |
|
| 1995 |
Lindberg I, van den Hurk WH, Bui C, Batie CJ. Enzymatic characterization of immunopurified prohormone convertase 2: potent inhibition by a 7B2 peptide fragment. Biochemistry. 34: 5486-93. PMID 7727407 DOI: 10.1021/Bi00016A020 |
0.512 |
|
| 1995 |
Zhou Y, Rovere C, Kitabgi P, Lindberg I. Mutational analysis of PC1 (SPC3) in PC12 cells. 66-kDa PC1 is fully functional. The Journal of Biological Chemistry. 270: 24702-6. PMID 7559585 DOI: 10.1074/Jbc.270.42.24702 |
0.422 |
|
| 1995 |
Lindberg I, Hurk WHvd, Bui C, Batie CJ. Enzymic characterization of immunopurified prohormone convertase 2: Potent inhibition by a 7B2 peptide fragment. [Erratum to document cited in CA122:259381] Biochemistry. 34: 7780-7780. DOI: 10.1021/Bi00023A027 |
0.408 |
|
| 1995 |
Lindberg I, Zhou Y. [5] Overexpression of neuropeptide precursors and processing enzymes Methods in Neurosciences. 23: 94-108. DOI: 10.1016/S1043-9471(06)80116-3 |
0.402 |
|
| 1994 |
Dupuy A, Lindberg I, Zhou Y, Akil H, Lazure C, Chrétien M, Seidah NG, Day R. Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms. Cleavage at a single arginine residue. Febs Letters. 337: 60-5. PMID 8276115 DOI: 10.1016/0014-5793(94)80630-6 |
0.429 |
|
| 1994 |
Lindberg I. Evidence for Cleavage of the PC1/PC3 Pro-Segment in the Endoplasmic Reticulum Molecular and Cellular Neuroscience. 5: 263-268. PMID 8087424 DOI: 10.1006/Mcne.1994.1030 |
0.386 |
|
| 1994 |
Martens GJM, Braks JAM, Eib DW, Zhou Y, Lindberg I. The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2 Proceedings of the National Academy of Sciences of the United States of America. 91: 5784-5787. PMID 8016065 DOI: 10.1073/Pnas.91.13.5784 |
0.47 |
|
| 1994 |
Lindberg I, Ahn SC, Breslin MB. Cellular distributions of the prohormone processing enzymes PC1 and PC2. Molecular and Cellular Neuroscience. 5: 614-622. PMID 7704436 DOI: 10.1006/Mcne.1994.1075 |
0.444 |
|
| 1993 |
Vindrola O, Lindberg I. Release of the prohormone convertase PC1 from AtT-20 cells Neuropeptides. 25: 151-160. PMID 8413860 DOI: 10.1016/0143-4179(93)90096-S |
0.429 |
|
| 1993 |
Hornby PJ, Rosenthal SD, Mathis JP, Vindrola O, Lindberg I. Immunocytochemical localization of the neuropeptide-synthesizing enzyme PC1 in AtT-20 cells. Neuroendocrinology. 58: 555-63. PMID 8115023 DOI: 10.1159/000126590 |
0.326 |
|
| 1992 |
Roberts SF, Irvine JW, Lindberg I. Characterization of proenkephalin-cleaving proteinases in bovine adrenal chromaffin granules using [35S]proenkephalin copolymerized into sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Journal of Neurochemistry. 58: 593-599. PMID 1729404 DOI: 10.1111/J.1471-4159.1992.Tb09760.X |
0.376 |
|
| 1992 |
Lindberg I, Shaw E. Posttranslational processing of proenkephalin in SK-N-MC cells: evidence for phosphorylation. Journal of Neurochemistry. 58: 448-453. PMID 1729392 DOI: 10.1111/J.1471-4159.1992.Tb09742.X |
0.43 |
|
| 1992 |
Lindberg I, Lincoln B, Rhodes CJ. Fluorometric assay of a calcium-dependent, paired-basic processing endopeptidase present in insulinoma granules Biochemical and Biophysical Research Communications. 183: 1-7. PMID 1543479 DOI: 10.1016/0006-291X(92)91599-L |
0.356 |
|
| 1992 |
Vindrola O, Lindberg I. Biosynthesis of the prohormone convertase mPC1 in AtT-20 cells. Molecular Endocrinology. 6: 1088-1094. PMID 1508222 DOI: 10.1210/Mend.6.7.1508222 |
0.398 |
|
| 1992 |
Mathis JP, Lindberg I. Posttranslational processing of proenkephalin in AtT-20 cells: evidence for cleavage at a Lys-Lys site. Endocrinology. 131: 2287-96. PMID 1425427 DOI: 10.1210/Endo.131.5.1425427 |
0.414 |
|
| 1991 |
Irvine JW, Lindberg I. Partial Purification and Characterization of a Putative Prohormone-Processing Enzyme Complex from Bovine Pituitary Endocrinology. 128: 2345-2352. PMID 2019254 DOI: 10.1210/Endo-128-5-2345 |
0.342 |
|
| 1991 |
Lindberg I, Shaw E, Finley J, Leone D, Deininger P. Posttranslational modifications of rat proenkephalin overexpressed in Chinese hamster ovary cells. Endocrinology. 128: 1849-56. PMID 2004604 DOI: 10.1210/Endo-128-4-1849 |
0.339 |
|
| 1991 |
Lindberg I. The new eukaryotic precursor processing proteinases. Molecular Endocrinology. 5: 1361-1365. PMID 1775127 DOI: 10.1210/Mend-5-10-1361 |
0.38 |
|
| 1990 |
Lindberg I, Thomas G. Cleavage of proenkephalin by a chromaffin granule processing enzyme. Endocrinology. 126: 480-487. PMID 2294000 DOI: 10.1210/Endo-126-1-480 |
0.355 |
|
| 1990 |
Irvine JW, Roberts SF, Lindberg I. Electrophoretic analysis of proteinases in sodium dodecyl sulfate-polyacrylamide gels containing copolymerized radiolabeled protein substrates: application to proenkephalin processing enzymes. Analytical Biochemistry. 190: 141-146. PMID 2285141 DOI: 10.1016/0003-2697(90)90147-2 |
0.34 |
|
| 1988 |
Shen F-, Lindberg I. Characterization of enkephalin-immunoreactive peptides generated by peptic digestion of rat plasma proteins. Endocrinology. 122: 2905-2910. PMID 3131127 DOI: 10.1210/Endo-122-6-2905 |
0.334 |
|
| 1987 |
Byrd JC, Naranjo JR, Lindberg I. Proenkephalin gene expression in the PC12 pheochromocytoma cell line: Stimulation by sodium butyrate Endocrinology. 121: 1299-1305. PMID 3653029 DOI: 10.1210/Endo-121-4-1299 |
0.43 |
|
| 1986 |
Lindberg I, White L. Reptilian enkephalins: implications for the evolution of proenkephalin. Archives of Biochemistry and Biophysics. 245: 1-7. PMID 3947092 DOI: 10.1016/0003-9861(86)90183-9 |
0.331 |
|
| 1986 |
Lindberg I, White L. Distribution of immunoreactive peptide B in the rat brain Biochemical and Biophysical Research Communications. 139: 1024-1032. PMID 3767990 DOI: 10.1016/S0006-291X(86)80280-7 |
0.407 |
|
| 1986 |
Wang Y, Lindberg I. Distribution and characterization of the opioid octapeptide met5-enkephalin-arg6-gly7-leu8 in the gastrointestinal tract of the rat. Cell and Tissue Research. 244: 77-85. PMID 3516403 DOI: 10.1007/Bf00218384 |
0.355 |
|
| 1982 |
Lindberg I, Yang HY, Costa E. An enkephalin-generating enzyme in bovine adrenal medulla. Biochemical and Biophysical Research Communications. 106: 186-93. PMID 7049167 DOI: 10.1016/0006-291X(82)92076-9 |
0.366 |
|
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