Tillman U. Gerngross - Publications

Affiliations: 
Engineering Dartmouth College, Hanover, NH, United States 
Area:
General Engineering, Biochemistry

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Vásquez M, Krauland E, Walker L, Wittrup D, Gerngross T. Connecting the sequence dots: shedding light on the genesis of antibodies reported to be designed in silico. Mabs. 1-6. PMID 31107637 DOI: 10.1080/19420862.2019.1611172  0.301
2016 Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, ... ... Gerngross TU, et al. Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak. Science (New York, N.Y.). PMID 26912366 DOI: 10.1126/Science.Aad5788  0.309
2015 Rouha H, Badarau A, Visram ZC, Battles MB, Prinz B, Magyarics Z, Nagy G, Mirkina I, Stulik L, Zerbs M, Jägerhofer M, Maierhofer B, Teubenbacher A, Dolezilkova I, Gross K, ... ... Gerngross TU, et al. Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody. Mabs. 7: 243-54. PMID 25523282 DOI: 10.4161/19420862.2014.985132  0.34
2011 Henderson GE, Isett KD, Gerngross TU. Site-specific modification of recombinant proteins: a novel platform for modifying glycoproteins expressed in E. coli. Bioconjugate Chemistry. 22: 903-12. PMID 21395336 DOI: 10.1021/Bc100510G  0.55
2011 Nett JH, Stadheim TA, Li H, Bobrowicz P, Hamilton SR, Davidson RC, Choi BK, Mitchell T, Bobrowicz B, Rittenhour A, Wildt S, Gerngross TU. A combinatorial genetic library approach to target heterologous glycosylation enzymes to the endoplasmic reticulum or the Golgi apparatus of Pichia pastoris. Yeast (Chichester, England). 28: 237-52. PMID 21360735 DOI: 10.1002/Yea.1835  0.394
2009 Gong B, Cukan M, Fisher R, Li H, Stadheim TA, Gerngross T. Characterization of N-linked glycosylation on recombinant glycoproteins produced in Pichia pastoris using ESI-MS and MALDI-TOF. Methods in Molecular Biology (Clifton, N.J.). 534: 213-23. PMID 19277549 DOI: 10.1007/978-1-59745-022-5_16  0.591
2008 Stadheim TA, Li H, Kett W, Burnina IN, Gerngross TU. Use of high-performance anion exchange chromatography with pulsed amperometric detection for O-glycan determination in yeast. Nature Protocols. 3: 1026-31. PMID 18546597 DOI: 10.1038/Nprot.2008.76  0.358
2007 Li H, Miele RG, Mitchell TI, Gerngross TU. N-linked glycan characterization of heterologous proteins. Methods in Molecular Biology (Clifton, N.J.). 389: 139-50. PMID 17951640 DOI: 10.1007/978-1-59745-456-8_10  0.381
2007 Ríos SE, Giaccone EM, Gerngross TU. Rapid screening of chromatography resins for the purification of proteins. Methods in Molecular Biology (Clifton, N.J.). 389: 99-106. PMID 17951637 DOI: 10.1007/978-1-59745-456-8_7  0.348
2007 Hamilton SR, Gerngross TU. Glycosylation engineering in yeast: the advent of fully humanized yeast. Current Opinion in Biotechnology. 18: 387-92. PMID 17951046 DOI: 10.1016/J.Copbio.2007.09.001  0.471
2006 Hamilton SR, Davidson RC, Sethuraman N, Nett JH, Jiang Y, Rios S, Bobrowicz P, Stadheim TA, Li H, Choi BK, Hopkins D, Wischnewski H, Roser J, Mitchell T, Strawbridge RR, ... ... Gerngross TU, et al. Humanization of yeast to produce complex terminally sialylated glycoproteins Science. 313: 1441-1443. PMID 16960007 DOI: 10.1126/Science.1130256  0.462
2006 Li H, Sethuraman N, Stadheim TA, Zha D, Prinz B, Ballew N, Bobrowicz P, Choi BK, Cook WJ, Cukan M, Houston-Cummings NR, Davidson R, Gong B, Hamilton SR, Hoopes JP, ... ... Gerngross TU, et al. Optimization of humanized IgGs in glycoengineered Pichia pastoris Nature Biotechnology. 24: 210-215. PMID 16429149 DOI: 10.1038/Nbt1178  0.518
2006 Reed DC, Barnard GC, Anderson EB, Klein LT, Gerngross TU. Production and purification of self-assembling peptides in Ralstonia eutropha. Protein Expression and Purification. 46: 179-88. PMID 16249097 DOI: 10.1016/J.Pep.2005.08.023  0.411
2005 Gerngross T. Production of complex human glycoproteins in yeast. Advances in Experimental Medicine and Biology. 564: 139. PMID 16400820 DOI: 10.1007/0-387-25515-X_24  0.31
2005 Barnard GC, McCool JD, Wood DW, Gerngross TU. Integrated recombinant protein expression and purification platform based on Ralstonia eutropha. Applied and Environmental Microbiology. 71: 5735-42. PMID 16204482 DOI: 10.1128/Aem.71.10.5735-5742.2005  0.443
2005 Banki MR, Gerngross TU, Wood DW. Novel and economical purification of recombinant proteins: intein-mediated protein purification using in vivo polyhydroxybutyrate (PHB) matrix association. Protein Science : a Publication of the Protein Society. 14: 1387-95. PMID 15883185 DOI: 10.1110/Ps.041296305  0.478
2005 Hamilton SR, Li H, Wischnewski H, Prasad A, Kerley-Hamilton JS, Mitchell T, Walling AJ, Davidson RC, Wildt S, Gerngross TU. Intact {alpha}-1,2-endomannosidase is a typical type II membrane protein. Glycobiology. 15: 615-24. PMID 15677381 DOI: 10.1093/Glycob/Cwi045  0.383
2004 Barnard GC, Henderson GE, Srinivasan S, Gerngross TU. High level recombinant protein expression in Ralstonia eutropha using T7 RNA polymerase based amplification. Protein Expression and Purification. 38: 264-71. PMID 15555942 DOI: 10.1016/J.Pep.2004.09.001  0.693
2004 Gerngross TU. Advances in the production of human therapeutic proteins in yeasts and filamentous fungi. Nature Biotechnology. 22: 1409-14. PMID 15529166 DOI: 10.1038/Nbt1028  0.495
2004 Ballew N, Gerngross T. Production of therapeutic proteins in fungal hosts. Expert Opinion On Biological Therapy. 4: 623-6. PMID 15155153 DOI: 10.1517/14712598.4.5.623  0.353
2004 Gerngross TU. Correction: Corrigendum: Advances in the production of human therapeutic proteins in yeasts and filamentous fungi Nature Biotechnology. 22: 1589-1589. DOI: 10.1038/Nbt1204-1589E  0.332
2003 Nett JH, Gerngross TU. Cloning and disruption of the PpURA5 gene and construction of a set of integration vectors for the stable genetic modification of Pichia pastoris. Yeast (Chichester, England). 20: 1279-90. PMID 14618566 DOI: 10.1002/Yea.1049  0.34
2003 Hamilton SR, Bobrowicz P, Bobrowicz B, Davidson RC, Li H, Mitchell T, Nett JH, Rausch S, Stadheim TA, Wischnewski H, Wildt S, Gerngross TU. Production of complex human glycoproteins in yeast. Science (New York, N.Y.). 301: 1244-6. PMID 12947202 DOI: 10.1126/Science.1088166  0.354
2003 Srinivasan S, Barnard GC, Gerngross TU. Production of recombinant proteins using multiple-copy gene integration in high-cell-density fermentations of Ralstonia eutropha. Biotechnology and Bioengineering. 84: 114-20. PMID 12910550 DOI: 10.1002/Bit.10756  0.619
2003 Choi BK, Bobrowicz P, Davidson RC, Hamilton SR, Kung DH, Li H, Miele RG, Nett JH, Wildt S, Gerngross TU. Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris. Proceedings of the National Academy of Sciences of the United States of America. 100: 5022-7. PMID 12702754 DOI: 10.1073/Pnas.0931263100  0.429
2002 Srinivasan S, Barnard GC, Gerngross TU. A novel high-cell-density protein expression system based on Ralstonia eutropha. Applied and Environmental Microbiology. 68: 5925-32. PMID 12450812 DOI: 10.1128/Aem.68.12.5925-5932.2002  0.61
1999 Boynton ZL, Koon JJ, Brennan EM, Clouart JD, Horowitz DM, Gerngross TU, Huisman GW. Reduction of cell lysate viscosity during processing of poly(3-hydroxyalkanoates) by chromosomal integration of the staphylococcal nuclease gene in Pseudomonas putida. Applied and Environmental Microbiology. 65: 1524-9. PMID 10103246 DOI: 10.1128/Aem.65.4.1524-1529.1999  0.364
1995 Gerngross TU, Martin DP. Enzyme-catalyzed synthesis of poly[(R)-(-)-3-hydroxybutyrate]: formation of macroscopic granules in vitro. Proceedings of the National Academy of Sciences of the United States of America. 92: 6279-83. PMID 7603982 DOI: 10.1073/Pnas.92.14.6279  0.312
1994 Gerngross TU, Snell KD, Peoples OP, Sinskey AJ, Csuhai E, Masamune S, Stubbe J. Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: evidence for a required posttranslational modification for catalytic activity. Biochemistry. 33: 9311-20. PMID 8049232 DOI: 10.1021/Bi00197A035  0.363
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