| Year |
Citation |
Score |
| 2023 |
McCann JJ, Fleenor DE, Chen J, Lai CH, Bass TE, Kastan MB. Participation of ATM, SMG1, and DDX5 in a DNA Damage-induced Alternative Splicing Pathway. Radiation Research. PMID 36921295 DOI: 10.1667/RADE-22-00219.1 |
0.366 |
|
| 2022 |
Bass TE, Fleenor DE, Burrell PE, Kastan MB. ATM Regulation of the Cohesin Complex is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double Strand Breaks. Molecular Cancer Research : McR. PMID 36469004 DOI: 10.1158/1541-7786.MCR-22-0399 |
0.346 |
|
| 2021 |
Chen J, Zhang D, Qin X, Owzar K, McCann JJ, Kastan MB. DNA-Damage-Induced Alternative Splicing of p53. Cancers. 13. PMID 33445417 DOI: 10.3390/cancers13020251 |
0.412 |
|
| 2017 |
Chen J, Kastan MB. A novel DNA damage-induced alternative splicing pathway that regulates p53 and cellular senescence markers. Oncoscience. 4: 122-123. PMID 29142900 DOI: 10.18632/oncoscience.367 |
0.389 |
|
| 2017 |
Liu X, Li F, Huang Q, Zhang Z, Zhou L, Deng Y, Zhou M, Fleenor DE, Wang H, Kastan MB, Li CY. Self-inflicted DNA double-strand breaks sustain tumorigenicity and stemness of cancer cells. Cell Research. PMID 28337983 DOI: 10.1038/Cr.2017.41 |
0.33 |
|
| 2017 |
Chen J, Crutchley J, Zhang D, Owzar K, Kastan MB. Identification of a DNA Damage-induced Alternative Splicing Pathway that Regulates p53 and Cellular Senescence Markers. Cancer Discovery. PMID 28288992 DOI: 10.1158/2159-8290.Cd-16-0908 |
0.41 |
|
| 2017 |
Kastan MB. Commentary on "Participation of p53 Protein in the Cellular Response to DNA Damage". Cancer Research. 76: 3663-5. PMID 27371738 DOI: 10.1158/0008-5472.CAN-16-1560 |
0.331 |
|
| 2015 |
Bakkenist CJ, Kastan MB. Chromatin perturbations during the DNA damage response in higher eukaryotes. Dna Repair. 36: 8-12. PMID 26391293 DOI: 10.1016/J.Dnarep.2015.09.002 |
0.341 |
|
| 2015 |
Goldstein M, Kastan MB. Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding. Cancer Research. 75: 2699-707. PMID 25939603 DOI: 10.1158/0008-5472.CAN-15-0400 |
0.335 |
|
| 2014 |
Henriksson S, Rassoolzadeh H, Hedström E, Coucoravas C, Julner A, Goldstein M, Imreh G, Zhivotovsky B, Kastan MB, Helleday T, Farnebo M. The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair. Genes & Development. 28: 2726-38. PMID 25512560 DOI: 10.1101/gad.246546.114 |
0.335 |
|
| 2014 |
Wang Q, Goldstein M, Alexander P, Wakeman TP, Sun T, Feng J, Lou Z, Kastan MB, Wang XF. Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks. The Embo Journal. 33: 862-77. PMID 24534091 DOI: 10.1002/Embj.201386064 |
0.327 |
|
| 2014 |
Guo K, Shelat AA, Guy RK, Kastan MB. Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors. Journal of Biomolecular Screening. 19: 538-46. PMID 24464432 DOI: 10.1177/1087057113520325 |
0.31 |
|
| 2010 |
Chen J, Kastan MB. 5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage. Genes & Development. 24: 2146-56. PMID 20837656 DOI: 10.1101/gad.1968910 |
0.344 |
|
| 2010 |
Derheimer FA, Kastan MB. Multiple roles of ATM in monitoring and maintaining DNA integrity. Febs Letters. 584: 3675-81. PMID 20580718 DOI: 10.1016/j.febslet.2010.05.031 |
0.322 |
|
| 2010 |
Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proceedings of the National Academy of Sciences of the United States of America. 107: 4153-8. PMID 20160076 DOI: 10.1073/Pnas.0913860107 |
0.311 |
|
| 2010 |
Chen J, Kastan M. Abstract 4: 5' - 3' UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage Cancer Research. 70: 4-4. DOI: 10.1158/1538-7445.Am10-4 |
0.404 |
|
| 2008 |
Rainey MD, Charlton ME, Stanton RV, Kastan MB. Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation Cancer Research. 68: 7466-7474. PMID 18794134 DOI: 10.1158/0008-5472.CAN-08-0763 |
0.32 |
|
| 2008 |
Chandhasin C, Ducu RI, Berkovich E, Kastan MB, Marriott SJ. Human T-cell leukemia virus type 1 tax attenuates the ATM-mediated cellular DNA damage response. Journal of Virology. 82: 6952-61. PMID 18434398 DOI: 10.1128/JVI.02331-07 |
0.334 |
|
| 2008 |
Kastan MB. DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award Lecture. Molecular Cancer Research : McR. 6: 517-24. PMID 18403632 DOI: 10.1158/1541-7786.MCR-08-0020 |
0.377 |
|
| 2008 |
Tang X, Hui ZG, Cui XL, Garg R, Kastan MB, Xu B. A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage. Molecular and Cellular Biology. 28: 2559-66. PMID 18250156 DOI: 10.1128/MCB.01711-07 |
0.331 |
|
| 2007 |
Loehberg CR, Thompson T, Kastan MB, Maclean KH, Edwards DG, Kittrell FS, Medina D, Conneely OM, O'Malley BW. Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. Cancer Research. 67: 12026-33. PMID 18089834 DOI: 10.1158/0008-5472.Can-07-3058 |
0.322 |
|
| 2007 |
Kastan MB. Our cells get stressed too! Implications for human disease. Blood Cells, Molecules & Diseases. 39: 148-50. PMID 17537652 DOI: 10.1016/j.bcmd.2007.04.002 |
0.36 |
|
| 2007 |
Berkovich E, Monnat RJ, Kastan MB. Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. Nature Cell Biology. 9: 683-90. PMID 17486112 DOI: 10.1038/Ncb1599 |
0.303 |
|
| 2006 |
Bekker-Jensen S, Lukas C, Kitagawa R, Melander F, Kastan MB, Bartek J, Lukas J. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. The Journal of Cell Biology. 173: 195-206. PMID 16618811 DOI: 10.1083/Jcb.200510130 |
0.326 |
|
| 2005 |
Morales M, Theunissen JW, Kim CF, Kitagawa R, Kastan MB, Petrini JH. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. Genes & Development. 19: 3043-54. PMID 16357220 DOI: 10.1101/Gad.1373705 |
0.308 |
|
| 2005 |
Takagi M, Absalon MJ, McLure KG, Kastan MB. Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. Cell. 123: 49-63. PMID 16213212 DOI: 10.1016/j.cell.2005.07.034 |
0.385 |
|
| 2005 |
Bartkova J, Bakkenist CJ, Rajpert-De Meyts E, Skakkebaek NE, Sehested M, Lukas J, Kastan MB, Bartek J. ATM activation in normal human tissues and testicular cancer. Cell Cycle (Georgetown, Tex.). 4: 838-45. PMID 15846060 DOI: 10.4161/Cc.4.6.1742 |
0.319 |
|
| 2005 |
Kastan M, Kitagawa R, Bakkenist C. DNA damage response pathways in cancer causation and treatment Breast Cancer Research. 7: 1-2. DOI: 10.1186/Bcr1049 |
0.444 |
|
| 2004 |
Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature. 432: 316-23. PMID 15549093 DOI: 10.1038/nature03097 |
0.331 |
|
| 2004 |
McLure KG, Takagi M, Kastan MB. NAD+ modulates p53 DNA binding specificity and function. Molecular and Cellular Biology. 24: 9958-67. PMID 15509798 DOI: 10.1128/MCB.24.22.9958-9967.2004 |
0.357 |
|
| 2004 |
Karlseder J, Hoke K, Mirzoeva OK, Bakkenist C, Kastan MB, Petrini JH, de Lange T. The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response. Plos Biology. 2: E240. PMID 15314656 DOI: 10.1371/Journal.Pbio.0020240 |
0.366 |
|
| 2004 |
Bakkenist CJ, Kastan MB. Phosphatases join kinases in DNA-damage response pathways. Trends in Cell Biology. 14: 339-41. PMID 15246426 DOI: 10.1016/J.Tcb.2004.05.001 |
0.317 |
|
| 2004 |
Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB. Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes & Development. 18: 1423-38. PMID 15175241 DOI: 10.1101/Gad.1200304 |
0.361 |
|
| 2004 |
Horejsí Z, Falck J, Bakkenist CJ, Kastan MB, Lukas J, Bartek J. Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation. Oncogene. 23: 3122-7. PMID 15048089 DOI: 10.1038/Sj.Onc.1207447 |
0.301 |
|
| 2003 |
Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature. 421: 499-506. PMID 12556884 DOI: 10.1038/Nature01368 |
0.333 |
|
| 2002 |
Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, Mathew CG, Kastan MB, Weaver DT, D'Andrea AD. Interaction of FANCD2 and NBS1 in the DNA damage response. Nature Cell Biology. 4: 913-20. PMID 12447395 DOI: 10.1038/Ncb879 |
0.323 |
|
| 2002 |
Kim ST, Xu B, Kastan MB. Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes & Development. 16: 560-70. PMID 11877376 DOI: 10.1101/gad.970602 |
0.304 |
|
| 2001 |
Thomas C, Ely G, James CD, Jenkins R, Kastan M, Jedlicka A, Burger P, Wharen R. Glioblastoma-related gene mutations and over-expression of functional epidermal growth factor receptors in SKMG-3 glioma cells Acta Neuropathologica. 101: 605-615. PMID 11515790 DOI: 10.1007/S004010000332 |
0.322 |
|
| 2001 |
Koumenis C, Alarcon R, Hammond E, Sutphin P, Hoffman W, Murphy M, Derr J, Taya Y, Lowe SW, Kastan M, Giaccia A. Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. Molecular and Cellular Biology. 21: 1297-310. PMID 11158315 DOI: 10.1128/Mcb.21.4.1297-1310.2001 |
0.428 |
|
| 1996 |
Gerson SL, Phillips W, Kastan M, Dumenco LL, Donovan C. Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU. Blood. 88: 1649-55. PMID 8781420 DOI: 10.1182/Blood.V88.5.1649.Bloodjournal8851649 |
0.305 |
|
| 1994 |
Smith ML, Chen IT, Zhan Q, Bae I, Chen CY, Gilmer TM, Kastan MB, O'Connor PM, Fornace AJ. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science (New York, N.Y.). 266: 1376-80. PMID 7973727 DOI: 10.1126/Science.7973727 |
0.451 |
|
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