Year |
Citation |
Score |
2022 |
Sazonovs A, Stevens CR, Venkataraman GR, Yuan K, Avila B, Abreu MT, Ahmad T, Allez M, Ananthakrishnan AN, Atzmon G, Baras A, Barrett JC, Barzilai N, Beaugerie L, Beecham A, ... ... Okou DT, et al. Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility. Nature Genetics. PMID 36038634 DOI: 10.1038/s41588-022-01156-2 |
0.778 |
|
2022 |
Jurickova I, Bonkowski E, Angerman E, Novak E, Huron A, Akers G, Iwasawa K, Braun T, Hadar R, Hooker M, Han S, Cutler DJ, Okou DT, Kugathasan S, Jegga A, et al. Eicosatetraynoic Acid and Butyrate Regulate Human Intestinal Organoid Mitochondrial and Extracellular Matrix Pathways Implicated in Crohn's Disease Strictures. Inflammatory Bowel Diseases. PMID 35259271 DOI: 10.1093/ibd/izac037 |
0.696 |
|
2022 |
Venkateswaran S, Somineni HK, Kilaru V, Katrinli S, Prince J, Okou DT, Hyams JS, Denson LA, Kellermayer R, Gibson G, Cutler DJ, Smith AK, Kugathasan S, Conneely KN. Methylation Quantitative Trait Loci are Largely Consistent across Disease States in Crohn's disease. G3 (Bethesda, Md.). PMID 35172000 DOI: 10.1093/g3journal/jkac041 |
0.787 |
|
2021 |
Somineni HK, Weitzner JH, Venkateswaran S, Dodd A, Prince J, Karikaran A, Sauer CG, Abramowicz S, Zwick ME, Cutler DJ, Okou DT, Chopra P, Kugathasan S. Site- and Taxa-Specific Disease-Associated Oral Microbial Structures Distinguish Inflammatory Bowel Diseases. Inflammatory Bowel Diseases. PMID 34002220 DOI: 10.1093/ibd/izab082 |
0.769 |
|
2021 |
Somineni HK, Nagpal S, Venkateswaran S, Cutler DJ, Okou DT, Haritunians T, Simpson CL, Begum F, Datta LW, Quiros AJ, Seminerio J, Mengesha E, Alexander JS, Baldassano RN, Dudley-Brown S, et al. Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. American Journal of Human Genetics. PMID 33600772 DOI: 10.1016/j.ajhg.2021.02.001 |
0.826 |
|
2021 |
Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, ElAbd H, Rosati E, Hübenthal M, Juzenas S, Abedian S, Vahedi H, Thelma BK, Yang SK, Ye BD, ... ... Okou DT, et al. Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations. Human Molecular Genetics. PMID 33555323 DOI: 10.1093/hmg/ddab017 |
0.656 |
|
2020 |
Shankar S, Bhandari I, Okou DT, Srinivasa G, Athri P. Predicting adverse drug reactions of two-drug combinations using structural and transcriptomic drug representations to train an artificial neural network. Chemical Biology & Drug Design. PMID 33006799 DOI: 10.1111/cbdd.13802 |
0.688 |
|
2019 |
Venkateswaran S, Denson LA, Jurickova I, Dodd A, Zwick ME, Cutler DJ, Kugathasan S, Okou DT. Neutrophil GM-CSF signaling in inflammatory bowel disease patients is influenced by non-coding genetic variants. Scientific Reports. 9: 9168. PMID 31235766 DOI: 10.1038/S41598-019-45701-2 |
0.802 |
|
2019 |
Wright M, Chandrakasan S, Okou DT, Yin H, Jurickova I, Denson LA, Kugathasan S. Early Onset Granulomatous Colitis Associated with a Mutation in NCF4 Resolved with Hematopoietic Stem Cell Transplantation. The Journal of Pediatrics. PMID 31027832 DOI: 10.1016/J.Jpeds.2019.03.042 |
0.612 |
|
2019 |
Somineni HK, Venkateswaran S, Kilaru V, Marigorta UM, Mo A, Okou DT, Kellermayer R, Mondal K, Cobb D, Walters TD, Griffiths A, Noe JD, Crandall WV, Rosh JR, Mack DR, et al. Blood-derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation. Gastroenterology. PMID 30779925 DOI: 10.1053/J.Gastro.2019.01.270 |
0.775 |
|
2019 |
Berauer JP, Mezina AI, Okou DT, Sabo A, Muzny DM, Gibbs RA, Hegde MR, Chopra P, Cutler DJ, Perlmutter DH, Bull LN, Thompson RJ, Loomes KM, Spinner NB, Rajagopalan R, et al. Identification of PKD1L1 Gene Variants in Children with the Biliary Atresia Splenic Malformation Syndrome. Hepatology (Baltimore, Md.). PMID 30664273 DOI: 10.1002/Hep.30515 |
0.567 |
|
2019 |
Somineni HK, Haritunians T, Simpson CL, Cutler DJ, Okou D, Itan Y, Venkateswaran S, Stevens C, Datta LW, Dhere TA, Lazarev M, Consortium EAAI, Zwick ME, Cho JH, Daly MJ, et al. Su1028 – Whole-Genome Sequencing of African Americans Identifies Novel Rare Variants Associated with Inflammatory Bowel Disease Gastroenterology. 156: S-488-S-489. DOI: 10.1016/S0016-5085(19)38082-5 |
0.821 |
|
2018 |
Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Alexander Valencia C, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, et al. Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. PMID 30124884 DOI: 10.1093/Ibd/Izy265 |
0.802 |
|
2018 |
Shaw KA, Cutler DJ, Okou D, Dodd A, Aronow BJ, Haberman Y, Stevens C, Walters TD, Griffiths A, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Kirschner BS, Heyman MB, et al. Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort. Genes and Immunity. PMID 29593342 DOI: 10.1038/S41435-018-0015-2 |
0.836 |
|
2018 |
Venkateswaran S, Prince J, Cutler DJ, Marigorta UM, Okou DT, Prahalad S, Mack D, Boyle B, Walters T, Griffiths A, Sauer CG, LeLeiko N, Keljo D, Markowitz J, Baker SS, et al. Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis. Inflammatory Bowel Diseases. 24: 829-838. PMID 29562276 DOI: 10.1093/Ibd/Izx084 |
0.816 |
|
2018 |
Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Quinn K, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, et al. Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn's Disease. Gastroenterology. PMID 29454792 DOI: 10.1053/J.Gastro.2018.02.016 |
0.801 |
|
2018 |
Somineni HK, Venkateswaran S, Kilaru V, Chopra P, Okou DT, Hyams JS, Denson LA, Cutler DJ, Gibson G, Conneely KN, Smith AK, Kugathasan S. 10 EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIED SHARED METHYLOMIC CONTRIBUTIONS TO SUSCEPTIBILITY AND PROGRESSION IN PEDIATRIC CROHN’S DISEASE Inflammatory Bowel Diseases. 24: S71-S71. DOI: 10.1093/ibd/izy038.017 |
0.744 |
|
2018 |
Somineni HK, Venkateswaran S, Kilaru V, Chopra P, Okou DT, Hyams JS, Denson LA, Cutler DJ, Gibson G, Conneely KN, Smith AK, Kugathasan S. 10 EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIED SHARED METHYLOMIC CONTRIBUTIONS TO SUSCEPTIBILITY AND PROGRESSION IN PEDIATRIC CROHN'S DISEASE Gastroenterology. 154: S101. DOI: 10.1053/J.Gastro.2017.11.238 |
0.792 |
|
2018 |
Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, et al. 27 CLINICAL AND GENOMIC CORRELATES OF NEUTROPHIL GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR SIGNALING IN PEDIATRIC CROHN DISEASE Gastroenterology. 154: S10-S11. DOI: 10.1053/j.gastro.2017.11.051 |
0.781 |
|
2018 |
Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, et al. 27 CLINICAL AND GENOMIC CORRELATES OF NEUTROPHIL GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR SIGNALING IN PEDIATRIC CROHN DISEASE Inflammatory Bowel Diseases. 24: S7-S8. DOI: 10.1053/J.Gastro.2017.11.051 |
0.808 |
|
2018 |
Jurickova I, Karns R, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, Walters TD, Griffiths AM, et al. 378 - Genomic Correlates of Reduced Neutrophil Granulocytemacrophage Colony Stimulating Factor Signaling in Stricturing Pediatric Crohn Disease Gastroenterology. 154: S-89-S-90. DOI: 10.1016/S0016-5085(18)30746-7 |
0.812 |
|
2017 |
Bertha M, Vasantharoopan A, Kumar A, Bruce BB, Prince J, Hofmekler T, Okou D, Chopra P, Wang G, Sauer C, Landers CJ, Hussain SZ, Cross RK, Baldassano RN, Kappelman MD, et al. IBD Serology and Disease Outcomes in African Americans With Crohn's Disease. Inflammatory Bowel Diseases. 24: 209-216. PMID 29272484 DOI: 10.1093/Ibd/Izx021 |
0.633 |
|
2017 |
Okou DT, Brant SR, Simpson CL, Haritunians T, Huang C, McGovern DPB, Kugathasan S. Reply. Gastroenterology. PMID 28482170 DOI: 10.1053/j.gastro.2017.05.006 |
0.531 |
|
2017 |
Denson LA, Jurickova I, Shaw K, Linn A, Dodd A, Okou D, Chalk C, Bonkowski E, Griffiths AM, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Heyman MB, Snapper SB, et al. Low Neutrophil Reactive Oxygen Species Production is Associated with Nicotinamide-Adenine Dinucleotide Phosphate (NADPH) Oxidase Gene Mutations and Refractory Colonic Involvement in Pediatric Crohn Disease Gastroenterology. 152: S955. DOI: 10.1016/S0016-5085(17)33247-X |
0.774 |
|
2017 |
Denson LA, Jurickova I, Shaw K, Linn A, Dodd A, Okou D, Chalk C, Bonkowski E, Griffiths AM, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Heyman MB, Snapper SB, et al. Reduced Neutrophil Granulocyte-Macrophage Colony Stimulating Factor Signaling is Associated with Granulocyte-Macrophage Colony Stimulating Factor Receptor Alpha Chain Gene Mutations and Stricturing Disease Complications in Pediatric Crohn Disease Gastroenterology. 152: S955. DOI: 10.1016/S0016-5085(17)33246-8 |
0.786 |
|
2017 |
Prince J, Venkateswaran S, Cutler DJ, Okou D, Chopra P, Davis S, Baker SS, Strople JA, Hommel KA, Evans JS, Sauer CG, Markowitz J, Rufo PA, Pfefferkorn MD, Ziring D, et al. Greater Contribution of HLA to Risk for Pediatric-Onset Ulcerative Colitis Can be Narrowed to 3 Independent Classic HLA Variants and Corresponding Amino Acid Changes Gastroenterology. 152: S954. DOI: 10.1016/S0016-5085(17)33244-4 |
0.697 |
|
2016 |
Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, et al. Genome-wide Association Study Identifies African-Specific Susceptibility Loci in African Americans with Inflammatory Bowel Disease. Gastroenterology. PMID 27693347 DOI: 10.1053/J.Gastro.2016.09.032 |
0.831 |
|
2015 |
Huang C, Haritunians T, Okou DT, Cutler DJ, Zwick ME, Taylor KD, Datta LW, Maranville JC, Liu Z, Ellis S, Chopra P, Alexander JS, Baldassano RN, Cross RK, Dassopoulos T, et al. Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans. Gastroenterology. PMID 26278503 DOI: 10.1053/J.Gastro.2015.07.065 |
0.813 |
|
2015 |
Cutler DJ, Zwick ME, Okou DT, Prahalad S, Walters T, Guthery SL, Dubinsky M, Baldassano R, Crandall WV, Rosh J, Markowitz J, Stephens M, Kellermayer R, Pfefferkorn M, Heyman MB, et al. Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping. Plos One. 10: e0128074. PMID 26098103 DOI: 10.1371/Journal.Pone.0128074 |
0.812 |
|
2015 |
Brant SR, Huang C, Haritunians T, Okou DT, Cutler DJ, Zwick ME, Datta LW, Taylor KD, Rotter JI, Bridges S, Kimberly RP, Rich SS, McGovern D, Kugathasan S. 387 Immunochip Implicates Multiple Genetic Loci for African American IBD Including HLA-DRB1*1502 for UC, NOD2, PTGER4, IL23R, LZKF3 and STAT5A/STAT3 for CD and Several Regions of Significant Admixture Linkage Disequilibrium Gastroenterology. 148: S-80. DOI: 10.1016/S0016-5085(15)30281-X |
0.798 |
|
2014 |
Okou DT, Kugathasan S. Role of genetics in pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 20: 1878-84. PMID 25118609 DOI: 10.1097/Mib.0000000000000085 |
0.623 |
|
2014 |
Okou DT, Mondal K, Faubion WA, Kobrynski LJ, Denson LA, Mulle JG, Ramachandran D, Xiong Y, Svingen P, Patel V, Bose P, Waters JP, Prahalad S, Cutler DJ, Zwick ME, et al. Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 58: 561-8. PMID 24792626 DOI: 10.1097/Mpg.0000000000000302 |
0.803 |
|
2013 |
Kaalla MJ, Broadaway KA, Rohani-Pichavant M, Conneely KN, Whiting A, Ponder L, Okou DT, Angeles-Han S, Rouster-Stevens K, Brown MR, Vogler LB, Jorde LB, Bohnsack JF, Epstein MP, Prahalad S. Meta-analysis confirms association between TNFA-G238A variant and JIA, and between PTPN22-C1858T variant and oligoarticular, RF-polyarticular and RF-positive polyarticular JIA. Pediatric Rheumatology Online Journal. 11: 40. PMID 24160187 DOI: 10.1186/1546-0096-11-40 |
0.305 |
|
2013 |
Middleton JP, Bhagavathula AP, Gaye B, Alvarez JA, Huang CS, Sauer CG, Tenjarla G, Schoen BT, Kumar A, Prasad M, Okou DT, Ifeadike WC, Dhere TA, Conneely KN, Ziegler TR, et al. Vitamin D status and bone mineral density in African American children with Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 57: 587-93. PMID 23760229 DOI: 10.1097/Mpg.0B013E31829E0B89 |
0.515 |
|
2013 |
Waters J, Dhere V, Benjamin A, Sekar A, Kumar A, Prahalad S, Okou DT, Kugathasan S. A practical and novel method to extract genomic DNA from blood collection kits for plasma protein preservation. Journal of Visualized Experiments : Jove. e4241. PMID 23711730 DOI: 10.3791/4241 |
0.459 |
|
2013 |
Kugathasan S, Okou DT, Mondal K, Benjamin AL, Kumar A, Hussain SZ, Katz J, Cross R, Moulton DE, Cutler DJ, Zwick ME. Su1743 Exome Sequencing Identify Novel Variants in African-Americans With Severe Perianal and Colonic Crohn's Disease Gastroenterology. 144: S-465. DOI: 10.1016/S0016-5085(13)61720-5 |
0.744 |
|
2013 |
Kugathasan S, Dubinsky M, Guthery SL, Okou DT, Bose P, Zwick ME, Cutler DJ, Waters JP, Hyams JS, Baldassano R, Stephens MC, Heyman MB, Griffiths AM, Crandall W, Markowitz J, et al. 976 Early Onset Crohn's Disease Exhibit Distinct Allele Architecture Differences and Reveal New IBD Loci Gastroenterology. 144: S-178. DOI: 10.1016/S0016-5085(13)60634-4 |
0.8 |
|
2012 |
Adeyanju O, Okou DT, Huang C, Kumar A, Sauer C, Galloway C, Prasad M, Waters J, Cutler DJ, Zwick ME, Dhere T, Kugathasan S. Common NOD2 risk variants in African Americans with Crohn's disease are due exclusively to recent Caucasian admixture. Inflammatory Bowel Diseases. 18: 2357-9. PMID 22447396 DOI: 10.1002/Ibd.22944 |
0.783 |
|
2011 |
Adeyanju O, Okou D, Huang C, Sauer C, Prasad M, Waters J, Ifeadike W, Benjamin A, Labaze S, Cutler D, Zwick M, Dhere T, Kugathasan S. Risk of NOD2 in African-American subjects with Crohnʼs disease is exclusively contributed by Caucasian admixture Inflammatory Bowel Diseases. 17: S77-S78. DOI: 10.1097/00054725-201112002-00255 |
0.752 |
|
2011 |
Dhere T, Hofmeckler T, Griglione N, Huang C, Sauer C, Tenjarla G, Schoen B, Ifeadike W, Olejeme H, Prasad M, Kumar A, Okou D, Galloway C, kugathasan S. Crohnʼs disease is 3 fold higher compared with ulcerative colitis among African-Americans; combined pediatric and adult data from the greater Atlanta area Inflammatory Bowel Diseases. 17: S56. DOI: 10.1097/00054725-201112002-00178 |
0.556 |
|
2011 |
Bhagavathula A, Gaye B, Alvarez J, Huang C, Tenjarla G, Sauer C, Schoen B, Prasad M, Waters J, Ifeadike W, Okou D, Ziegler T, Tangprincha V, Kugathasan S. Vitamin D deficiency is found in 2/3 of African American population regardless of underlying IBD or not and the Vitamin D levels are not influenced by disease severity or location in AA population Inflammatory Bowel Diseases. 17: S6. DOI: 10.1097/00054725-201112002-00015 |
0.482 |
|
2009 |
Okou DT, Locke AE, Steinberg KM, Hagen K, Athri P, Shetty AC, Patel V, Zwick ME. Combining microarray-based genomic selection (MGS) with the Illumina Genome Analyzer platform to sequence diploid target regions. Annals of Human Genetics. 73: 502-13. PMID 19573206 DOI: 10.1111/J.1469-1809.2009.00530.X |
0.764 |
|
2009 |
Passalacqua KD, Varadarajan A, Ondov BD, Okou DT, Zwick ME, Bergman NH. Structure and complexity of a bacterial transcriptome. Journal of Bacteriology. 191: 3203-11. PMID 19304856 DOI: 10.1128/Jb.00122-09 |
0.619 |
|
2008 |
Hegde MR, Chin EL, Mulle JG, Okou DT, Warren ST, Zwick ME. Microarray-based mutation detection in the dystrophin gene. Human Mutation. 29: 1091-9. PMID 18663755 DOI: 10.1002/Humu.20831 |
0.609 |
|
2008 |
Steinberg KM, Okou DT, Zwick ME. Applying rapid genome sequencing technologies to characterize pathogen genomes. Analytical Chemistry. 80: 520-8. PMID 18320606 DOI: 10.1021/Ac086027Z |
0.621 |
|
2007 |
Okou DT, Steinberg KM, Middle C, Cutler DJ, Albert TJ, Zwick ME. Microarray-based genomic selection for high-throughput resequencing. Nature Methods. 4: 907-9. PMID 17934469 DOI: 10.1038/Nmeth1109 |
0.7 |
|
2001 |
Chiang CF, Okou DT, Griffin TB, Verret CR, Williams MN. Green fluorescent protein rendered susceptible to proteolysis: positions for protease-sensitive insertions. Archives of Biochemistry and Biophysics. 394: 229-35. PMID 11594737 DOI: 10.1006/Abbi.2001.2537 |
0.599 |
|
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