Benjamin Wolozin - Publications

Affiliations: 
Pharmacology Boston University School of Medicine, Boston, MA 
Area:
Alzheimer's, Parkinson's, ALS, neurodegeneration, microtubule associated protein tau
Website:
http://www.bumc.bu.edu/busm-pm/faculty/faculty-profiles/wolozin/

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jiang L, Roberts R, Wong M, Zhang L, Webber CJ, Libera J, Wang Z, Kilci A, Jenkins M, Ortiz AR, Dorrian L, Sun J, Sun G, Rashad S, Kornbrek C, ... ... Wolozin B, et al. β-amyloid accumulation enhances microtubule associated protein tau pathology in an APP/MAPT mouse model of Alzheimer's disease. Frontiers in Neuroscience. 18: 1372297. PMID 38572146 DOI: 10.3389/fnins.2024.1372297  0.321
2021 Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, Lei S, Song J, Alvarez VE, Hovde S, ... ... Wolozin B, et al. Interaction of tau with HNRNPA2B1 and N-methyladenosine RNA mediates the progression of tauopathy. Molecular Cell. PMID 34453888 DOI: 10.1016/j.molcel.2021.07.038  0.301
2020 Webber CJ, Lei SE, Wolozin B. The pathophysiology of neurodegenerative disease: Disturbing the balance between phase separation and irreversible aggregation. Progress in Molecular Biology and Translational Science. 174: 187-223. PMID 32828466 DOI: 10.1016/Bs.Pmbts.2020.04.021  0.404
2020 Reiss AB, Glass AD, Wisniewski T, Wolozin B, Gomolin IH, Pinkhasov A, De Leon J, Stecker MM. Alzheimer's disease: many failed trials, so where do we go from here? Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 68: 1135-1140. PMID 32699179 DOI: 10.1136/Jim-2020-001297  0.392
2020 LeBlang CJ, Medalla M, Nicoletti NW, Hays EC, Zhao J, Shattuck J, Cruz AL, Wolozin B, Luebke JI. Reduction of the RNA Binding Protein TIA1 Exacerbates Neuroinflammation in Tauopathy. Frontiers in Neuroscience. 14: 285. PMID 32327969 DOI: 10.3389/Fnins.2020.00285  0.396
2020 Pourhaghighi R, Ash PEA, Phanse S, Goebels F, Hu LZM, Chen S, Zhang Y, Wierbowski SD, Boudeau S, Moutaoufik MT, Malty RH, Malolepsza E, Tsafou K, Nathan A, Cromar G, ... ... Wolozin B, et al. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Systems. 10: 333-350.e14. PMID 32325033 DOI: 10.1016/J.Cels.2020.03.003  0.314
2020 Li M, Reisman J, Morris-Eppolito B, Qian SX, Kazis LE, Wolozin B, Goldstein LE, Xia W. Beneficial association of angiotensin-converting enzyme inhibitors and statins on the occurrence of possible Alzheimer's disease after traumatic brain injury. Alzheimer's Research & Therapy. 12: 33. PMID 32220235 DOI: 10.1186/S13195-020-00589-3  0.338
2019 Cruz A, Verma M, Wolozin B. The Pathophysiology of Tau and Stress Granules in Disease. Advances in Experimental Medicine and Biology. 1184: 359-372. PMID 32096049 DOI: 10.1007/978-981-32-9358-8_26  0.376
2019 Apicco DJ, Zhang C, Maziuk B, Jiang L, Ballance HI, Boudeau S, Ung C, Li H, Wolozin B. Dysregulation of RNA Splicing in Tauopathies. Cell Reports. 29: 4377-4388.e4. PMID 31875547 DOI: 10.1016/J.Celrep.2019.11.093  0.371
2019 Wolozin B, Ivanov P. Stress granules and neurodegeneration Nature Reviews Neuroscience. 20: 649-666. PMID 31582840 DOI: 10.1038/S41583-019-0222-5  0.398
2019 Gan Q, Yao H, Na H, Ballance H, Tao Q, Leung L, Tian H, Zhu H, Wolozin B, Qiu WQ. Effects of Amylin Against Amyloid-β-Induced Tauopathy and Synapse Loss in Primary Neurons. Journal of Alzheimer's Disease : Jad. PMID 31306122 DOI: 10.3233/Jad-190161  0.369
2019 Wolozin B. The Evolution of Phase-Separated TDP-43 in Stress. Neuron. 102: 265-267. PMID 30998893 DOI: 10.1016/J.Neuron.2019.03.041  0.305
2019 Sotiropoulos I, Silva J, Rodrigues S, Gomes P, Dioli C, Soares-Cunha C, Takashima A, Wolozin B, Sousa N. Novel Insights Of Tau Rna-Protein Biology In The Precipitating Role Of Chronic Stress On Alzheimer’S Disease Brain Pathology Alzheimers & Dementia. 15: 1643. DOI: 10.1016/J.Jalz.2019.06.4892  0.381
2018 Jiang L, Ash PEA, Maziuk BF, Ballance HI, Boudeau S, Abdullatif AA, Orlando M, Petrucelli L, Ikezu T, Wolozin B. TIA1 regulates the generation and response to toxic tau oligomers. Acta Neuropathologica. PMID 30465259 DOI: 10.1007/S00401-018-1937-5  0.402
2018 Silva JM, Rodrigues S, Sampaio-Marques B, Gomes P, Neves-Carvalho A, Dioli C, Soares-Cunha C, Mazuik BF, Takashima A, Ludovico P, Wolozin B, Sousa N, Sotiropoulos I. Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. Cell Death and Differentiation. PMID 30442948 DOI: 10.1038/S41418-018-0217-1  0.422
2018 Maziuk BF, Apicco DJ, Cruz AL, Jiang L, Ash PEA, da Rocha EL, Zhang C, Yu WH, Leszyk J, Abisambra JF, Li H, Wolozin B. RNA binding proteins co-localize with small tau inclusions in tauopathy. Acta Neuropathologica Communications. 6: 71. PMID 30068389 DOI: 10.1186/S40478-018-0574-5  0.431
2018 Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, ... ... Wolozin B, et al. Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo. Nature Neuroscience. 21: 72-80. PMID 29273772 DOI: 10.1038/S41593-017-0022-Z  0.411
2017 Maziuk B, Ballance HI, Wolozin B. Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders. Frontiers in Molecular Neuroscience. 10: 89. PMID 28420962 DOI: 10.3389/Fnmol.2017.00089  0.431
2017 Zhu H, Xue X, Wang E, Wallack M, Na H, Hooker JM, Kowall N, Tao Q, Stein TD, Wolozin B, Qiu WQ. Amylin receptor ligands reduce the pathological cascade of Alzheimer's disease. Neuropharmacology. PMID 28363773 DOI: 10.1016/J.Neuropharm.2017.03.030  0.389
2017 Wolozin B, Apicco DJ, Zhang C, Ash PEA, Maziuk B, Abdullatif AA, Ballance H, Goldberg LR, Yazdani N, Ung C, Kanaan NM, Ikezu T, Bryant CD, Li H. Tau-Induced Neurodegeneration Is Mediated By Rna Binding Proteins Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.07.157  0.346
2016 Kuwahara T, Inoue K, D'Agati VD, Fujimoto T, Eguchi T, Saha S, Wolozin B, Iwatsubo T, Abeliovich A. LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts. Scientific Reports. 6: 29945. PMID 27424887 DOI: 10.1038/Srep29945  0.35
2016 Ostrowski SM, Johnson K, Siefert M, Shank S, Sironi L, Wolozin B, Landreth GE, Ziady AG. Simvastatin inhibits protein isoprenylation in the brain. Neuroscience. PMID 27180285 DOI: 10.1016/J.Neuroscience.2016.04.053  0.373
2016 Vanderweyde T, Apicco DJ, Youmans-Kidder K, Ash PE, Cook C, Lummertz da Rocha E, Jansen-West K, Frame AA, Citro A, Leszyk JD, Ivanov P, Abisambra JF, Steffen M, Li H, Petrucelli L, ... Wolozin B, et al. Interaction of tau with the RNA-binding Protein TIA1 Regulates tau Pathophysiology and Toxicity. Cell Reports. PMID 27160897 DOI: 10.1016/J.Celrep.2016.04.045  0.409
2016 Meier S, Bell M, Lyons DN, Rodriguez-Rivera J, Ingram A, Fontaine SN, Mechas E, Chen J, Wolozin B, LeVine H, Zhu H, Abisambra JF. Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1001-7. PMID 26791227 DOI: 10.1523/Jneurosci.3029-15.2016  0.418
2016 Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nature Communications. 7: 10332. PMID 26755131 DOI: 10.1038/Ncomms10332  0.328
2016 Ikezu T, Ikezu S, Varnum M, Wolozin B, Butovsky O, Kügler S, Medalla M, Luebke J, Haydar TF. O4-04-01: Microglial Exosomes Propagate Tau Protein from the Entorhinal Cortex to the Hippocampus: An Early Pathophysiology of Alzheimer's Disease Alzheimer's & Dementia. 12: P339-P340. DOI: 10.1016/J.Jalz.2016.06.624  0.375
2016 Sotiropoulos I, Rodrigues S, Silva J, Wolozin B, Sousa N. P4-081: Environmental Stress and Glucocorticoids Trigger an HDAC6-Dependent Induction of Stress Granules and TAU Aggregation: Implications For Alzheimer's Disease Alzheimer's & Dementia. 12: P1044-P1044. DOI: 10.1016/J.Jalz.2016.06.2170  0.368
2015 Wolozin B, Ikezu T. Syk and Yea Shall Find. Ebiomedicine. 2: 1590-1. PMID 26870779 DOI: 10.1016/J.Ebiom.2015.11.012  0.451
2015 Asai H, Ikezu S, Tsunoda S, Medalla M, Luebke J, Haydar T, Wolozin B, Butovsky O, Kügler S, Ikezu T. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nature Neuroscience. 18: 1584-93. PMID 26436904 DOI: 10.1038/Nn.4132  0.412
2015 Saha S, Ash PE, Gowda V, Liu L, Shirihai O, Wolozin B. Mutations in LRRK2 potentiate age-related impairment of autophagic flux. Molecular Neurodegeneration. 10: 26. PMID 26159606 DOI: 10.1186/S13024-015-0022-Y  0.31
2015 Wolozin B, Apicco D. RNA binding proteins and the genesis of neurodegenerative diseases. Advances in Experimental Medicine and Biology. 822: 11-5. PMID 25416971 DOI: 10.1007/978-3-319-08927-0_3  0.386
2015 Vanderweyde T, Youmans-Kidder K, Apicco DJ, Ash PEA, Cook C, Petrucelli L, Wolozin B. Interaction between microtubule-associated protein tau and RNA binding proteins stimulates tau misfolding and stress granule formation Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.417  0.374
2014 Ash PE, Vanderweyde TE, Youmans KL, Apicco DJ, Wolozin B. Pathological stress granules in Alzheimer's disease. Brain Research. 1584: 52-8. PMID 25108040 DOI: 10.1016/J.Brainres.2014.05.052  0.388
2014 Boon JY, Dusonchet J, Trengrove C, Wolozin B. Interaction of LRRK2 with kinase and GTPase signaling cascades. Frontiers in Molecular Neuroscience. 7: 64. PMID 25071441 DOI: 10.3389/Fnmol.2014.00064  0.357
2014 Dusonchet J, Li H, Guillily M, Liu M, Stafa K, Derada Troletti C, Boon JY, Saha S, Glauser L, Mamais A, Citro A, Youmans KL, Liu L, Schneider BL, Aebischer P, ... ... Wolozin B, et al. A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity. Human Molecular Genetics. 23: 4887-905. PMID 24794857 DOI: 10.1093/Hmg/Ddu202  0.345
2014 Liu-Yesucevitz L, Lin AY, Ebata A, Boon JY, Reid W, Xu YF, Kobrin K, Murphy GJ, Petrucelli L, Wolozin B. ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4167-74. PMID 24647938 DOI: 10.1523/Jneurosci.2350-13.2014  0.339
2014 Saha S, Liu-Yesucevitz L, Wolozin B. Regulation of autophagy by LRRK2 in Caenorhabditis elegans. Neuro-Degenerative Diseases. 13: 110-3. PMID 24192129 DOI: 10.1159/000355654  0.337
2014 Boyd JD, Lee-Armandt JP, Feiler MS, Zaarur N, Liu M, Kraemer B, Concannon JB, Ebata A, Wolozin B, Glicksman MA. A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity. Journal of Biomolecular Screening. 19: 44-56. PMID 24019256 DOI: 10.1177/1087057113501553  0.362
2013 Leung A, Nah SK, Reid W, Ebata A, Koch CM, Monti S, Genereux JC, Wiseman RL, Wolozin B, Connors LH, Berk JL, Seldin DC, Mostoslavsky G, Kotton DN, Murphy GJ. Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis. Stem Cell Reports. 1: 451-63. PMID 24286032 DOI: 10.1016/J.Stemcr.2013.10.003  0.343
2013 Vanderweyde T, Youmans K, Liu-Yesucevitz L, Wolozin B. Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review. Gerontology. 59: 524-33. PMID 24008580 DOI: 10.1159/000354170  0.442
2013 Rodriguez-Ortiz CJ, Hoshino H, Cheng D, Liu-Yescevitz L, Blurton-Jones M, Wolozin B, LaFerla FM, Kitazawa M. Neuronal-specific overexpression of a mutant valosin-containing protein associated with IBMPFD promotes aberrant ubiquitin and TDP-43 accumulation and cognitive dysfunction in transgenic mice. The American Journal of Pathology. 183: 504-15. PMID 23747512 DOI: 10.1016/J.Ajpath.2013.04.014  0.376
2013 Wolozin B, Vanderwyede T, Liu-Yesucevitz L, Dedeoglu A, Petrucelli L, Duff K. P4-034: Viewing neurodegeneration beyond the tangle: The role of RNA binding proteins in Alzheimer's disease Alzheimer's & Dementia. 9: P715-P716. DOI: 10.1016/J.Jalz.2013.05.1422  0.389
2012 Wolozin B. Regulated protein aggregation: stress granules and neurodegeneration. Molecular Neurodegeneration. 7: 56. PMID 23164372 DOI: 10.1186/1750-1326-7-56  0.397
2012 Vanderweyde T, Yu H, Varnum M, Liu-Yesucevitz L, Citro A, Ikezu T, Duff K, Wolozin B. Contrasting pathology of the stress granule proteins TIA-1 and G3BP in tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8270-83. PMID 22699908 DOI: 10.1523/Jneurosci.1592-12.2012  0.469
2012 Youmans KL, Wolozin B. TDP-43: a new player on the AD field? Experimental Neurology. 237: 90-5. PMID 22691390 DOI: 10.1016/J.Expneurol.2012.05.018  0.378
2012 Di Domenico F, Sultana R, Ferree A, Smith K, Barone E, Perluigi M, Coccia R, Pierce W, Cai J, Mancuso C, Squillace R, Wiengele M, Dalle-Donne I, Wolozin B, Butterfield DA. Redox proteomics analyses of the influence of co-expression of wild-type or mutated LRRK2 and Tau on C. elegans protein expression and oxidative modification: relevance to Parkinson disease. Antioxidants & Redox Signaling. 17: 1490-506. PMID 22315971 DOI: 10.1089/Ars.2011.4312  0.377
2012 Wolozin B. Statins and therapy of Alzheimer's disease: questions of efficacy versus trial design. Alzheimer's Research & Therapy. 4: 3. PMID 22264400 DOI: 10.1186/Alzrt101  0.371
2012 Ferree A, Guillily M, Li H, Smith K, Takashima A, Squillace R, Weigele M, Collins JJ, Wolozin B. Regulation of physiologic actions of LRRK2: focus on autophagy. Neuro-Degenerative Diseases. 10: 238-41. PMID 22204929 DOI: 10.1159/000332599  0.379
2011 Liu-Yesucevitz L, Bassell GJ, Gitler AD, Hart AC, Klann E, Richter JD, Warren ST, Wolozin B. Local RNA translation at the synapse and in disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16086-93. PMID 22072660 DOI: 10.1523/Jneurosci.4105-11.2011  0.363
2011 Chan D, Citro A, Cordy JM, Shen GC, Wolozin B. Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2). The Journal of Biological Chemistry. 286: 16140-9. PMID 21454543 DOI: 10.1074/Jbc.M111.234005  0.345
2011 Wolozin B, Gabel C, Ferree A, Guillily M, Ebata A. Watching worms whither: modeling neurodegeneration in C. elegans. Progress in Molecular Biology and Translational Science. 100: 499-514. PMID 21377635 DOI: 10.1016/B978-0-12-384878-9.00015-7  0.395
2011 Wolozin B, Vanderwyede T, Liu-Yesucevitz L, McKee A, Duff K. O3-05-02: Stress granules and Alzheimer's disease: Colocalization with tau pathology Alzheimer's & Dementia. 7: S507-S507. DOI: 10.1016/J.Jalz.2011.05.1417  0.374
2010 Liu-Yesucevitz L, Bilgutay A, Zhang YJ, Vanderweyde T, Vanderwyde T, Citro A, Mehta T, Zaarur N, McKee A, Bowser R, Sherman M, Petrucelli L, Wolozin B. Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue. Plos One. 5: e13250. PMID 20948999 DOI: 10.1371/Journal.Pone.0013250  0.396
2010 Hsu CH, Chan D, Wolozin B. LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins. Neuro-Degenerative Diseases. 7: 68-75. PMID 20173330 DOI: 10.1159/000285509  0.339
2010 Kumar A, Greggio E, Beilina A, Kaganovich A, Chan D, Taymans JM, Wolozin B, Cookson MR. The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation. Plos One. 5: e8730. PMID 20090955 DOI: 10.1371/Journal.Pone.0008730  0.327
2010 Carballo-Carbajal I, Weber-Endress S, Rovelli G, Chan D, Wolozin B, Klein CL, Patenge N, Gasser T, Kahle PJ. Leucine-rich repeat kinase 2 induces alpha-synuclein expression via the extracellular signal-regulated kinase pathway. Cellular Signalling. 22: 821-7. PMID 20074637 DOI: 10.1016/J.Cellsig.2010.01.006  0.315
2010 Hsu CH, Chan D, Greggio E, Saha S, Guillily MD, Ferree A, Raghavan K, Shen GC, Segal L, Ryu H, Cookson MR, Wolozin B. MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2. Journal of Neurochemistry. 112: 1593-604. PMID 20067578 DOI: 10.1111/J.1471-4159.2010.06568.X  0.395
2010 Wolozin B. C. elegans models of Alzheimer's disease and Parkinson's disease: Systems biology identifies LRRK2 shared interaction networks Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.517  0.341
2010 Wolozin B, Guillily M, Ferree A, Li H, Pyenson N, Smith K, Saha S, Ebata A, Gabel CV, Collins JJ. C. elegans models of Alzheimer's disease and Parkinson's disease: Systems biology identifies an interaction between tau and LRRK2 Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.232  0.375
2009 Saha S, Guillily MD, Ferree A, Lanceta J, Chan D, Ghosh J, Hsu CH, Segal L, Raghavan K, Matsumoto K, Hisamoto N, Kuwahara T, Iwatsubo T, Moore L, Goldstein L, ... ... Wolozin B, et al. LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9210-8. PMID 19625511 DOI: 10.1523/Jneurosci.2281-09.2009  0.315
2009 Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S. Leptin: a novel therapeutic strategy for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 16: 731-40. PMID 19387109 DOI: 10.3233/Jad-2009-1021  0.389
2008 Zerbinatti CV, Cordy JM, Chen CD, Guillily M, Suon S, Ray WJ, Seabrook GR, Abraham CR, Wolozin B. Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein. Molecular Neurodegeneration. 3: 5. PMID 18348724 DOI: 10.1186/1750-1326-3-5  0.394
2008 Wolozin B, Saha S, Guillily M, Ferree A, Riley M. Investigating convergent actions of genes linked to familial Parkinson's disease. Neuro-Degenerative Diseases. 5: 182-5. PMID 18322385 DOI: 10.1159/000113697  0.308
2008 Wolozin B, Lee A, Lee A, Whitmer R, Kazis L. O1-05-05: Use of angiotensin receptor blockers is associated with a lower incidence and progression of Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.251  0.321
2007 Wolozin B, Wang SW, Li NC, Lee A, Lee TA, Kazis LE. Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease. Bmc Medicine. 5: 20. PMID 17640385 DOI: 10.1186/1741-7015-5-20  0.351
2006 Wolozin B, Bednar MM. Interventions for heart disease and their effects on Alzheimer's disease. Neurological Research. 28: 630-6. PMID 16945215 DOI: 10.1179/016164106X130515  0.369
2006 Wolozin B, Manger J, Bryant R, Cordy J, Green RC, McKee A. Re-assessing the relationship between cholesterol, statins and Alzheimer's disease. Acta Neurologica Scandinavica. Supplementum. 185: 63-70. PMID 16866913 DOI: 10.1111/J.1600-0404.2006.00687.X  0.367
2006 Takashima A, Shimojo M, Wolozin B. The players on the gamma-secretase team. Nature Medicine. 12: 766-7; discussion 76. PMID 16829940 DOI: 10.1038/Nm0706-766  0.31
2006 Cordy JM, Zerbinatti CV, Chen C, Guillily M, Ray WJ, Seabrook GR, Abraham CR, Wolozin B. P4-077: Modulation of amyloid precursor protein-processing by oxysterol-binding protein Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1815  0.333
2005 Lee TA, Wolozin B, Weiss KB, Bednar MM. Assessment of the emergence of Alzheimer's disease following coronary artery bypass graft surgery or percutaneous transluminal coronary angioplasty. Journal of Alzheimer's Disease : Jad. 7: 319-24. PMID 16131734 DOI: 10.3233/Jad-2005-7408  0.307
2005 Poon HF, Frasier M, Shreve N, Calabrese V, Wolozin B, Butterfield DA. Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease. Neurobiology of Disease. 18: 492-8. PMID 15755676 DOI: 10.1016/J.Nbd.2004.12.009  0.333
2005 Frasier M, Walzer M, McCarthy L, Magnuson D, Lee JM, Haas C, Kahle P, Wolozin B. Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein. Experimental Neurology. 192: 274-87. PMID 15755545 DOI: 10.1016/J.Expneurol.2004.07.016  0.367
2005 Snyder H, Mensah K, Hsu C, Hashimoto M, Surgucheva IG, Festoff B, Surguchov A, Masliah E, Matouschek A, Wolozin B. beta-Synuclein reduces proteasomal inhibition by alpha-synuclein but not gamma-synuclein. The Journal of Biological Chemistry. 280: 7562-9. PMID 15591046 DOI: 10.1074/Jbc.M412887200  0.309
2004 Snyder H, Wolozin B. Pathological proteins in Parkinson's disease: focus on the proteasome. Journal of Molecular Neuroscience : Mn. 24: 425-42. PMID 15655264 DOI: 10.1385/Jmn:24:3:425  0.331
2004 Wolozin B. Cholesterol, statins and dementia. Current Opinion in Lipidology. 15: 667-72. PMID 15529026 DOI: 10.1097/00041433-200412000-00007  0.375
2004 Wolozin B, Brown J, Theisler C, Silberman S. The cellular biochemistry of cholesterol and statins: insights into the pathophysiology and therapy of Alzheimer's disease. Cns Drug Reviews. 10: 127-46. PMID 15179443 DOI: 10.1111/J.1527-3458.2004.Tb00009.X  0.368
2004 Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B. Differential expression of cholesterol hydroxylases in Alzheimer's disease. The Journal of Biological Chemistry. 279: 34674-81. PMID 15148325 DOI: 10.1074/Jbc.M402324200  0.4
2004 Petrucelli L, Dickson D, Kehoe K, Taylor J, Snyder H, Grover A, De Lucia M, McGowan E, Lewis J, Prihar G, Kim J, Dillmann WH, Browne SE, Hall A, Voellmy R, ... ... Wolozin B, et al. CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Human Molecular Genetics. 13: 703-14. PMID 14962978 DOI: 10.1093/Hmg/Ddh083  0.406
2004 Wolozin B. Cholesterol and the biology of Alzheimer's disease. Neuron. 41: 7-10. PMID 14715130 DOI: 10.1016/S0896-6273(03)00840-7  0.378
2004 Wolozin B, Brown J, Silberman S, Theisler C, Yager D, Crawley J, Magnuson D, Reiss A, Lee JM, Eckman C. P4-191 Differential expression of cholesterol 24-hydroxylase and cholesterol 27-hydroxylase in Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81749-4  0.32
2004 Wolozin B, Lee TA, Weiss K, Bednar MM. S1-03-06 Reduced incidence of Alzheimer's disease among subjects exposed to general anesthesia in non-cardiac operations: a retrospective analysis Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80021-6  0.31
2003 Choi P, Snyder H, Petrucelli L, Theisler C, Chong M, Zhang Y, Lim K, Chung KK, Kehoe K, D'Adamio L, Lee JM, Cochran E, Bowser R, Dawson TM, Wolozin B. SEPT5_v2 is a parkin-binding protein. Brain Research. Molecular Brain Research. 117: 179-89. PMID 14559152 DOI: 10.1016/S0169-328X(03)00318-8  0.327
2003 Perry G, Castellani RJ, Smith MA, Harris PL, Kubat Z, Ghanbari K, Jones PK, Cordone G, Tabaton M, Wolozin B, Ghanbari H. Oxidative damage in the olfactory system in Alzheimer's disease. Acta Neuropathologica. 106: 552-6. PMID 12955399 DOI: 10.1007/S00401-003-0761-7  0.359
2003 Pappolla MA, Bryant-Thomas TK, Herbert D, Pacheco J, Fabra Garcia M, Manjon M, Girones X, Henry TL, Matsubara E, Zambon D, Wolozin B, Sano M, Cruz-Sanchez FF, Thal LJ, Petanceska SS, et al. Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology. Neurology. 61: 199-205. PMID 12874399 DOI: 10.1212/01.Wnl.0000070182.02537.84  0.356
2003 Snyder H, Mensah K, Theisler C, Lee J, Matouschek A, Wolozin B. Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function. The Journal of Biological Chemistry. 278: 11753-9. PMID 12551928 DOI: 10.1074/Jbc.M208641200  0.317
2003 Wolozin B. Cyp46 (24S-cholesterol hydroxylase): a genetic risk factor for Alzheimer disease. Archives of Neurology. 60: 16-8. PMID 12533083 DOI: 10.1001/Archneur.60.1.16  0.309
2002 Egashira N, Iwasaki K, Ishibashi M, Hatip-Al-Khatib I, Wolozin B, Mishima K, Irie K, Fujiwara M. Hypoxia enhances beta-amyloid-induced apoptosis in rat cultured hippocampal neurons. Japanese Journal of Pharmacology. 90: 321-7. PMID 12501008 DOI: 10.1254/Jjp.90.321  0.329
2002 Petrucelli L, O'Farrell C, Lockhart PJ, Baptista M, Kehoe K, Vink L, Choi P, Wolozin B, Farrer M, Hardy J, Cookson MR. Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons. Neuron. 36: 1007-19. PMID 12495618 DOI: 10.1016/S0896-6273(02)01125-X  0.335
2002 Wolozin B. Cholesterol and Alzheimer's disease. Biochemical Society Transactions. 30: 525-9. PMID 12196129 DOI: 10.1042/Bst0300525  0.347
2002 Ahn BH, Rhim H, Kim SY, Sung YM, Lee MY, Choi JY, Wolozin B, Chang JS, Lee YH, Kwon TK, Chung KC, Yoon SH, Hahn SJ, Kim MS, Jo YH, et al. alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells. The Journal of Biological Chemistry. 277: 12334-42. PMID 11821392 DOI: 10.1074/Jbc.M110414200  0.338
2001 Wolozin B. Peering into proteolysis with presenilins. Journal of Alzheimer's Disease : Jad. 3: 191-193. PMID 12214060 DOI: 10.3233/Jad-2001-3204  0.387
2001 Wolozin B. A fluid connection: cholesterol and Abeta. Proceedings of the National Academy of Sciences of the United States of America. 98: 5371-3. PMID 11344276 DOI: 10.1073/Pnas.101123198  0.369
2000 Wolozin B, Kellman W, Ruosseau P, Celesia GG, Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Archives of Neurology. 57: 1439-43. PMID 11030795 DOI: 10.1001/Archneur.57.10.1439  0.332
2000 Choi P, Ostrerova-Golts N, Sparkman D, Cochran E, Lee JM, Wolozin B. Parkin is metabolized by the ubiquitin/proteosome system. Neuroreport. 11: 2635-8. PMID 10976934 DOI: 10.1097/00001756-200008210-00006  0.308
2000 Wolozin B, Behl C. Mechanisms of neurodegenerative disorders: Part 2: control of cell death. Archives of Neurology. 57: 801-4. PMID 10867776 DOI: 10.1001/Archneur.57.6.801  0.358
2000 Wolozin B, Behl C. Mechanisms of neurodegenerative disorders: Part 1: protein aggregates. Archives of Neurology. 57: 793-6. PMID 10867775 DOI: 10.1001/Archneur.57.6.793  0.345
2000 Palacino JJ, Berechid BE, Alexander P, Eckman C, Younkin S, Nye JS, Wolozin B. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells. The Journal of Biological Chemistry. 275: 215-22. PMID 10617607 DOI: 10.1074/Jbc.275.1.215  0.345
2000 Ostrerova-Golts N, Petrucelli L, Hardy J, Lee JM, Farer M, Wolozin B. The A53T α-Synuclein Mutation Increases Iron-Dependent Aggregation and Toxicity The Journal of Neuroscience. 20: 6048-6054. DOI: 10.1523/Jneurosci.20-16-06048.2000  0.31
2000 Wolozin B. The physiology and pathophysiology of α-synuclein: A protein chaperone that aggregates Neurobiology of Aging. 21: 283. DOI: 10.1016/S0197-4580(00)83224-8  0.314
1999 Sunderland T, Wolozin B, Galasko D, Levy J, Dukoff R, Bahro M, Lasser R, Motter R, Lehtimäki T, Seubert P. Longitudinal stability of CSF tau levels in Alzheimer patients. Biological Psychiatry. 46: 750-5. PMID 10494442 DOI: 10.1016/S0006-3223(99)00143-2  0.343
1999 Ostrerova N, Petrucelli L, Farrer M, Mehta N, Choi P, Hardy J, Wolozin B. α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins The Journal of Neuroscience. 19: 5782-5791. DOI: 10.1523/Jneurosci.19-14-05782.1999  0.35
1998 Wolozin B, Maheshwari S, Jones C, Dukoff R, Wallace W, Racchi M, Nagula S, Shulman NR, Sunderland T, Bush A. Beta-amyloid augments platelet aggregation: reduced activity of familial angiopathy-associated mutants. Molecular Psychiatry. 3: 500-7. PMID 9857975 DOI: 10.1038/Sj.Mp.4000451  0.329
1998 Murayama M, Tanaka S, Palacino J, Murayama O, Honda T, Sun X, Yasutake K, Nihonmatsu N, Wolozin B, Takashima A. Direct association of presenilin-1 with beta-catenin. Febs Letters. 433: 73-7. PMID 9738936 DOI: 10.1016/S0014-5793(98)00886-2  0.316
1998 Takashima A, Murayama M, Murayama O, Kohno T, Honda T, Yasutake K, Nihonmatsu N, Mercken M, Yamaguchi H, Sugihara S, Wolozin B. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau. Proceedings of the National Academy of Sciences of the United States of America. 95: 9637-41. PMID 9689133 DOI: 10.1073/Pnas.95.16.9637  0.361
1998 Wolozin B, Alexander P, Palacino J. Regulation of apoptosis by presenilin 1. Neurobiology of Aging. 19: S23-7. PMID 9562463 DOI: 10.1016/S0197-4580(98)00041-4  0.312
1997 Luo Y, Hawver DB, Iwasaki K, Sunderland T, Roth GS, Wolozin B. Physiological levels of beta-amyloid peptide stimulate protein kinase C in PC12 cells. Brain Research. 769: 287-95. PMID 9374197 DOI: 10.1016/S0006-8993(97)00718-X  0.36
1996 Vito P, Wolozin B, Ganjei JK, Iwasaki K, Lacanà E, D'Adamio L. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. The Journal of Biological Chemistry. 271: 31025-8. PMID 8940094 DOI: 10.1074/Jbc.271.49.31025  0.304
1996 Wolozin B, Iwasaki K, Vito P, Ganjei JK, Lacanà E, Sunderland T, Zhao B, Kusiak JW, Wasco W, D'Adamio L. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science (New York, N.Y.). 274: 1710-3. PMID 8939861 DOI: 10.1126/Science.274.5293.1710  0.403
1996 Luo Y, Sunderland T, Roth GS, Wolozin B. Physiological levels of beta-amyloid peptide promote PC12 cell proliferation. Neuroscience Letters. 217: 125-8. PMID 8916088 DOI: 10.1016/0304-3940(96)13087-1  0.347
1994 Johnson GS, Basaric-Keys J, Ghanbari HA, Lebovics RS, Lesch KP, Merril CR, Sunderland T, Wolozin B. Protein alterations in olfactory neuroblasts from Alzheimer donors. Neurobiology of Aging. 15: 675-80. PMID 7891821 DOI: 10.1016/0197-4580(94)90048-5  0.38
1993 Wolozin B, Lesch P, Lebovics R, Sunderland T. Olfactory neuroblasts from Alzheimer donors: Studies on APP processing and cell regulation Biological Psychiatry. 34: 824-838. PMID 8110910 DOI: 10.1016/0006-3223(93)90051-E  0.387
1992 Wolozin B, Bacic M, Merrill MJ, Lesch KP, Chen C, Lebovics RS, Sunderland T. Differential expression of carboxyl terminal derivatives of amyloid precursor protein among cell lines. Journal of Neuroscience Research. 33: 163-9. PMID 1453480 DOI: 10.1002/Jnr.490330121  0.38
1988 Wolozin B, Scicutella A, Davies P. Reexpression of a developmentally regulated antigen in Down syndrome and Alzheimer disease Proceedings of the National Academy of Sciences of the United States of America. 85: 6202-6206. PMID 2970636 DOI: 10.1073/Pnas.85.16.6202  0.341
1987 Wolozin B, Davies P. Alzheimer-related neuronal protein A68: Specificity and distribution Annals of Neurology. 22: 521-526. PMID 3435070 DOI: 10.1002/Ana.410220412  0.364
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