| Year |
Citation |
Score |
| 2024 |
Moreira PI, Avila J, Galimberti D, Pappolla MA, Plascencia-Villa G, Sorensen AA, Zhu X, Perry G. Therapeutic Trials in Alzheimer's Disease: Where Are We Now? Journal of Alzheimer's Disease : Jad. 101: S1-S2. PMID 39422966 DOI: 10.3233/JAD-249016 |
0.63 |
|
| 2024 |
Correia SC, Perry G, Moreira PI. Fueling Alzheimer's Disease: Where Does Immunometabolism Stand? Journal of Alzheimer's Disease : Jad. 100: S363-S385. PMID 39177607 DOI: 10.3233/JAD-240787 |
0.682 |
|
| 2024 |
Carvalho C, Moreira PI. MitoTempo protects against nε-carboxymethyl lysine-induced mitochondrial dyshomeostasis and neuronal cells injury. Free Radical Biology & Medicine. 220: 192-206. PMID 38734265 DOI: 10.1016/j.freeradbiomed.2024.05.011 |
0.351 |
|
| 2024 |
Cardoso S, Carvalho C, Correia SC, Moreira PI. Protective effects of 2,4-dinitrophenol in okadaic acid-induced cellular model of Alzheimer's disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1870: 167222. PMID 38729530 DOI: 10.1016/j.bbadis.2024.167222 |
0.722 |
|
| 2023 |
Sousa T, Moreira PI, Cardoso S. Current Advances in Mitochondrial Targeted Interventions in Alzheimer's Disease. Biomedicines. 11. PMID 37760774 DOI: 10.3390/biomedicines11092331 |
0.395 |
|
| 2023 |
Carvalho C, Moreira PI. Metabolic defects shared by Alzheimer's disease and diabetes: A focus on mitochondria. Current Opinion in Neurobiology. 79: 102694. PMID 36842275 DOI: 10.1016/j.conb.2023.102694 |
0.368 |
|
| 2022 |
Carvalho C, Correia SC, Seiça R, Moreira PI. WWOX inhibition by Zfra1-31 restores mitochondrial homeostasis and viability of neuronal cells exposed to high glucose. Cellular and Molecular Life Sciences : Cmls. 79: 487. PMID 35984507 DOI: 10.1007/s00018-022-04508-7 |
0.686 |
|
| 2022 |
Correia SC, Alves MG, Oliveira PF, Casadesus G, LaManna J, Perry G, Moreira PI. Hypoxic preconditioning averts sporadic Alzheimer's disease-like phenotype in rats: a focus on mitochondria. Antioxidants & Redox Signaling. PMID 35316086 DOI: 10.1089/ars.2019.8007 |
0.804 |
|
| 2021 |
Correia SC, Moreira PI. Oxygen Sensing and Signaling in Alzheimer's Disease: A Breathtaking Story! Cellular and Molecular Neurobiology. PMID 34510330 DOI: 10.1007/s10571-021-01148-6 |
0.685 |
|
| 2021 |
Fernandes T, Resende R, Silva DF, Marques AP, Santos AE, Cardoso SM, Domingues MR, Moreira PI, Pereira CF. Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer's Disease. Biomedicines. 9. PMID 34440085 DOI: 10.3390/biomedicines9080881 |
0.376 |
|
| 2021 |
Rodrigues-Neves AC, Carecho R, Correia SC, Carvalho C, Campos EJ, Baptista FI, Moreira PI, Ambrósio AF. Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer's Disease. Molecular Neurobiology. PMID 33606195 DOI: 10.1007/s12035-021-02316-x |
0.66 |
|
| 2021 |
Correia SC, Machado NJ, Alves MG, Oliveira PF, Moreira PI. Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33466445 DOI: 10.3390/ijms22010461 |
0.705 |
|
| 2020 |
Quinn PMJ, Moreira PI, Ambrósio AF, Alves CH. PINK1/PARKIN signalling in neurodegeneration and neuroinflammation. Acta Neuropathologica Communications. 8: 189. PMID 33168089 DOI: 10.1186/s40478-020-01062-w |
0.389 |
|
| 2020 |
Cardoso S, Moreira PI. Antidiabetic drugs for Alzheimer's and Parkinson's diseases: Repurposing insulin, metformin, and thiazolidinediones. International Review of Neurobiology. 155: 37-64. PMID 32854858 DOI: 10.1016/bs.irn.2020.02.010 |
0.441 |
|
| 2020 |
Cunnane SC, Trushina E, Morland C, Prigione A, Casadesus G, Andrews ZB, Beal MF, Bergersen LH, Brinton RD, de la Monte S, Eckert A, Harvey J, Jeggo R, Jhamandas JH, Kann O, ... ... Moreira PI, et al. Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nature Reviews. Drug Discovery. PMID 32709961 DOI: 10.1038/S41573-020-0072-X |
0.654 |
|
| 2020 |
Duarte AI, Candeias E, Alves IN, Mena D, Silva DF, Machado NJ, Campos EJ, Santos MS, Oliveira CR, Moreira PI. Liraglutide Protects Against Brain Amyloid-β Accumulation in Female Mice with Early Alzheimer's Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation. International Journal of Molecular Sciences. 21. PMID 32143329 DOI: 10.3390/ijms21051746 |
0.457 |
|
| 2020 |
Resende R, Fernandes T, Pereira AC, De Pascale J, Marques AP, Oliveira P, Morais S, Santos V, Madeira N, Pereira C, Moreira PI. Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do mitochondria-associated membranes (MAMs) play a role? Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165752. PMID 32119897 DOI: 10.1016/J.Bbadis.2020.165752 |
0.35 |
|
| 2020 |
Ferreira H, Martins J, Nunes A, Moreira PI, Castelo-Branco M, Ambrósio AF, Serranho P, Bernardes R. Characterization of the retinal changes of the 3×Tg-AD mouse model of Alzheimer’s disease Health Technology. 10: 875-883. DOI: 10.1007/978-3-030-31635-8_220 |
0.368 |
|
| 2019 |
Coimbra JR, Sobral PJ, Santos AE, Moreira PI, Salvador JA. An overview of glutaminyl cyclase inhibitors for Alzheimer's disease. Future Medicinal Chemistry. 11: 3179-3194. PMID 31838899 DOI: 10.4155/fmc-2019-0163 |
0.443 |
|
| 2019 |
Pinho BR, Duarte AI, Canas PM, Moreira PI, Murphy MP, Oliveira JA. The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice. Free Radical Biology & Medicine. PMID 31751762 DOI: 10.1016/j.freeradbiomed.2019.11.021 |
0.406 |
|
| 2019 |
Chiquita S, Campos EJ, Castelhano J, Ribeiro M, Sereno J, Moreira PI, Castelo-Branco M, Ambrósio AF. Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer's disease: a longitudinal multimodal in vivo study. Alzheimer's Research & Therapy. 11: 90. PMID 31722748 DOI: 10.1186/s13195-019-0542-8 |
0.413 |
|
| 2019 |
Pereira CF, Santos AE, Moreira PI, Pereira AC, Sousa FJ, Cardoso SM, Cruz MT. Is Alzheimer's disease an inflammasomopathy? Ageing Research Reviews. 100966. PMID 31577960 DOI: 10.1016/J.Arr.2019.100966 |
0.503 |
|
| 2019 |
Correia SC, Carvalho C, Cardoso S, Moreira PI. Post-translational modifications in brain health and disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 31102788 DOI: 10.1016/J.Bbadis.2019.05.006 |
0.656 |
|
| 2019 |
Carvalho C, Cardoso SM, Correia SC, Moreira PI. Tortuous Paths of Insulin Signaling and Mitochondria in Alzheimer's Disease. Advances in Experimental Medicine and Biology. 1128: 161-183. PMID 31062330 DOI: 10.1007/978-981-13-3540-2_9 |
0.735 |
|
| 2019 |
Chiquita S, Ribeiro M, Castelhano J, Oliveira F, Sereno J, Batista M, Abrunhosa A, Rodrigues-Neves AC, Carecho R, Baptista F, Gomes C, Moreira PI, Ambrósio AF, Castelo-Branco M. A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss. Human Molecular Genetics. PMID 30816415 DOI: 10.1093/hmg/ddz045 |
0.391 |
|
| 2019 |
Chiquita S, Rodrigues-Neves AC, Baptista FI, Carecho R, Moreira PI, Castelo-Branco M, Ambrósio AF. The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer's Disease: Critical Aspects to Unravel. Molecular Neurobiology. PMID 30612332 DOI: 10.1007/s12035-018-1461-6 |
0.443 |
|
| 2019 |
Rodrigues-Neves AC, Carecho R, Baptista F, Moreira P, Ambrósio A. Can the retina show similar molecular and cellular changes as the brain in an animal model of Alzheimer’s disease? Frontiers in Cellular Neuroscience. 13. DOI: 10.3389/Conf.Fncel.2019.01.00020 |
0.36 |
|
| 2019 |
Bernardes R, Ferreira H, Martins J, Moreira PI, Castelo‐Branco M, Ambrósio AF, Serranho P. Retinal thickness of the triple‐transgenic mice model of Alzheimer\’s disease at the age of one month Acta Ophthalmologica. 97. DOI: 10.1111/J.1755-3768.2019.5467 |
0.334 |
|
| 2018 |
Pinho TS, Correia SC, Perry G, Ambrósio AF, Moreira PI. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30412792 DOI: 10.1016/J.Bbadis.2018.10.037 |
0.751 |
|
| 2018 |
Cardoso S, Moreira PI. Diabesity and brain disturbances: A metabolic perspective. Molecular Aspects of Medicine. PMID 30321556 DOI: 10.1016/j.mam.2018.10.002 |
0.363 |
|
| 2018 |
Carvalho C, Moreira PI. Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events. Frontiers in Physiology. 9: 806. PMID 30018565 DOI: 10.3389/fphys.2018.00806 |
0.501 |
|
| 2018 |
Duarte AI, Sjögren M, Santos MS, Oliveira CR, Moreira PI, Björkqvist M. Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's Disease. Scientific Reports. 8: 8961. PMID 29895889 DOI: 10.1038/s41598-018-27121-w |
0.339 |
|
| 2018 |
Coimbra JRM, Marques DFF, Baptista SJ, Pereira CMF, Moreira PI, Dinis TCP, Santos AE, Salvador JAR. Highlights in BACE1 Inhibitors for Alzheimer's Disease Treatment. Frontiers in Chemistry. 6: 178. PMID 29881722 DOI: 10.3389/fchem.2018.00178 |
0.463 |
|
| 2018 |
Pinho TS, Verde DM, Correia SC, Cardoso SM, Moreira PI. O-GlcNAcylation and neuronal energy status: implications for Alzheimer's disease. Ageing Research Reviews. PMID 29787816 DOI: 10.1016/J.Arr.2018.05.003 |
0.709 |
|
| 2018 |
Perry G, Avila J, Moreira PI, Sorensen AA, Tabaton M. Preface. Journal of Alzheimer's Disease : Jad. PMID 29782320 DOI: 10.3233/JAD-179945 |
0.545 |
|
| 2018 |
Moreira PI. Sweet Mitochondria: A Shortcut to Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 62: 1391-1401. PMID 29562542 DOI: 10.3233/JAD-170931 |
0.487 |
|
| 2018 |
Mendes D, Oliveira MM, Moreira PI, Coutinho J, Nunes FM, Pereira DM, Valentão P, Andrade PB, Videira RA. Beneficial effects of white wine polyphenols-enriched diet on Alzheimer's disease-like pathology. The Journal of Nutritional Biochemistry. 55: 165-177. PMID 29525608 DOI: 10.1016/j.jnutbio.2018.02.001 |
0.443 |
|
| 2018 |
Duarte AI, Santos MS, Oliveira CR, Moreira PI. Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease. Neuropharmacology. PMID 29471055 DOI: 10.1016/j.neuropharm.2018.01.044 |
0.443 |
|
| 2018 |
Marques-Aleixo I, Santos-Alves E, Oliveira PJ, Moreira PI, Magalhães J, Ascensão A. The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy. Biochimica Et Biophysica Acta. PMID 29408395 DOI: 10.1016/j.bbcan.2018.01.002 |
0.331 |
|
| 2018 |
Duarte AI, Sjögren M, Mena D, Alves IN, Santos MS, Oliveira CR, Moreira PI, Björkqvist M. I11 Effects of dual administration of liraglutide and ghrelin on brain mitochondrial metabolism in the r6/2 mouse Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Ehdn.247 |
0.357 |
|
| 2018 |
Pinho BR, Duarte AI, Almeida LM, Canas PM, Moreira PI, Murphy MP, Oliveira JM. I10 Effects of MITOQ on behavioural and biochemical phenotypes of a huntington’s disease mouse model Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Ehdn.246 |
0.336 |
|
| 2017 |
Cardoso S, Seiça R, Moreira PI. Diabesity and Brain Energy Metabolism: The Case of Alzheimer's Disease. Advances in Neurobiology. 19: 117-150. PMID 28933063 DOI: 10.1007/978-3-319-63260-5_5 |
0.405 |
|
| 2017 |
Cardoso S, Seiça RM, Moreira PI. Uncoupling Protein 2 Inhibition Exacerbates Glucose Fluctuation-Mediated Neuronal Effects. Neurotoxicity Research. PMID 28875237 DOI: 10.1007/s12640-017-9805-y |
0.382 |
|
| 2017 |
Candeias E, Sebastião I, Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI, Duarte AI. Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats. Molecular Neurobiology. PMID 28573460 DOI: 10.1007/s12035-017-0622-3 |
0.383 |
|
| 2017 |
Bastos P, Ferreira R, Manadas B, Moreira PI, Vitorino R. Insights into the human brain proteome: Disclosing the biological meaning of protein networks in cerebrospinal fluid. Critical Reviews in Clinical Laboratory Sciences. 1-20. PMID 28393582 DOI: 10.1080/10408363.2017.1299682 |
0.383 |
|
| 2017 |
Cardoso SM, Correia SC, Carvalho C, Moreira PI. Mitochondria in Alzheimer's Disease and Diabetes-Associated Neurodegeneration: License to Heal! Handbook of Experimental Pharmacology. PMID 28251365 DOI: 10.1007/164_2017_3 |
0.726 |
|
| 2017 |
Neves AC, Chiquita S, Carecho R, Campos E, Moreira P, Baptista F, Ambrósio F. Alzheimer's disease: can the retina be a window to the brain? Acta Ophthalmologica. 95. DOI: 10.1111/J.1755-3768.2017.01564 |
0.448 |
|
| 2016 |
Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. Journal of Alzheimer's Disease : Jad. PMID 27802219 DOI: 10.3233/JAD-151208 |
0.54 |
|
| 2016 |
Candeias E, Duarte AI, Sebastião I, Fernandes MA, Plácido AI, Carvalho C, Correia S, Santos RX, Seiça R, Santos MS, Oliveira CR, Moreira PI. Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology. Molecular Neurobiology. PMID 27730513 DOI: 10.1007/S12035-016-0155-1 |
0.798 |
|
| 2016 |
Correia SC, Perry G, Moreira PI. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. Biochimica Et Biophysica Acta. PMID 27460705 DOI: 10.1016/J.Bbadis.2016.07.010 |
0.733 |
|
| 2016 |
Cardoso S, Seiça RM, Moreira PI. Mitochondria as a target for neuroprotection: implications for Alzheimer´s disease. Expert Review of Neurotherapeutics. PMID 27366815 DOI: 10.1080/14737175.2016.1205488 |
0.493 |
|
| 2016 |
Cardoso S, Carvalho C, Correia SC, Seiça RM, Moreira PI. Alzheimeŕs disease: From mitochondrial perturbations to mitochondrial medicine. Brain Pathology (Zurich, Switzerland). PMID 27327899 DOI: 10.1111/Bpa.12402 |
0.73 |
|
| 2016 |
Moreira P. Energy demand and energy supply in Alzheimer's Disease. An Introduction. Brain Pathology (Zurich, Switzerland). PMID 27327396 DOI: 10.1111/bpa.12398 |
0.343 |
|
| 2016 |
Plácido AI, Pereira CM, Correira SC, Carvalho C, Oliveira CR, Moreira PI. Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells. Molecular Neurobiology. PMID 26732598 DOI: 10.1007/s12035-015-9640-1 |
0.459 |
|
| 2016 |
Alves MG, Almeida S, Nunes AR, Sousa M, Moreira PI, Oliveira PF, Silva BM. Polyphenols As Protective Agents Against Neurotoxicity And Neurodegeneration: The Case Of Tea Polyphenols Journal of the International Society of Antioxidants in Nutrition & Health. 3. DOI: 10.18143/Jisanh_V3I4_1422 |
0.313 |
|
| 2015 |
Marques-Aleixo I, Santos-Alves E, Balça MM, Moreira PI, Oliveira PJ, Magalhães J, Ascensão A. Physical exercise mitigates doxorubicin-induced brain cortex and cerebellum mitochondrial alterations and cellular quality control signaling. Mitochondrion. 26: 43-57. PMID 26678157 DOI: 10.1016/j.mito.2015.12.002 |
0.44 |
|
| 2015 |
Candeias EM, Sebastião IC, Cardoso SM, Correia SC, Carvalho CI, Plácido AI, Santos MS, Oliveira CR, Moreira PI, Duarte AI. Gut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutide. World Journal of Diabetes. 6: 807-27. PMID 26131323 DOI: 10.4239/Wjd.V6.I6.807 |
0.682 |
|
| 2015 |
Marques-Aleixo I, Santos-Alves E, Balça MM, Rizo-Roca D, Moreira PI, Oliveira PJ, Magalhães J, Ascensão A. Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers. Neuroscience. 301: 480-95. PMID 26116519 DOI: 10.1016/j.neuroscience.2015.06.027 |
0.419 |
|
| 2015 |
Carvalho C, Correia SC, Cardoso S, Plácido AI, Candeias E, Duarte AI, Moreira PI. The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases. Expert Review of Neurotherapeutics. 15: 867-84. PMID 26092668 DOI: 10.1586/14737175.2015.1058160 |
0.741 |
|
| 2015 |
Carvalho C, Santos MS, Oliveira CR, Moreira PI. Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers. Biochimica Et Biophysica Acta. 1852: 1665-75. PMID 25960150 DOI: 10.1016/j.bbadis.2015.05.001 |
0.443 |
|
| 2015 |
Placido AI, Pereira CM, Duarte AI, Candeias E, Correia SC, Carvalho C, Cardoso S, Oliveira CR, Moreira PI. Modulation of endoplasmic reticulum stress: an opportunity to prevent neurodegeneration? Cns & Neurological Disorders Drug Targets. 14: 518-33. PMID 25921746 DOI: 10.2174/1871527314666150429112353 |
0.703 |
|
| 2015 |
Nunes AR, Alves MG, Tomás GD, Conde VR, Cristóvão AC, Moreira PI, Oliveira PF, Silva BM. Daily consumption of white tea (Camellia sinensis (L.)) improves the cerebral cortex metabolic and oxidative profile in prediabetic Wistar rats. The British Journal of Nutrition. 113: 832-42. PMID 25716141 DOI: 10.1017/S0007114514004395 |
0.322 |
|
| 2015 |
Correia SC, Resende R, Moreira PI, Pereira CM. Alzheimer's disease-related misfolded proteins and dysfunctional organelles on autophagy menu. Dna and Cell Biology. 34: 261-73. PMID 25664381 DOI: 10.1089/dna.2014.2757 |
0.72 |
|
| 2015 |
Monteiro-Cardoso VF, Castro M, Oliveira MM, Moreira PI, Peixoto F, Videira RA. Age-dependent biochemical dysfunction in skeletal muscle of triple-transgenic mouse model of Alzheimer`s disease. Current Alzheimer Research. 12: 100-15. PMID 25654504 DOI: 10.2174/1567205012666150204124852 |
0.398 |
|
| 2015 |
Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 25608860 DOI: 10.1007/S00702-015-1367-7 |
0.809 |
|
| 2015 |
Sena CM, Pereira AM, Carvalho C, Fernandes R, Seiça RM, Oliveira CR, Moreira PI. Type 2 diabetes aggravates Alzheimer's disease-associated vascular alterations of the aorta in mice. Journal of Alzheimer's Disease : Jad. 45: 127-38. PMID 25471187 DOI: 10.3233/JAD-141008 |
0.413 |
|
| 2015 |
Cardoso S, Correia S, Carvalho C, Candeias E, Plácido AI, Duarte AI, Seiça RM, Moreira PI. Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection. Journal of Bioenergetics and Biomembranes. 47: 119-31. PMID 25217852 DOI: 10.1007/S10863-014-9580-X |
0.712 |
|
| 2015 |
Monteiro-Cardoso VF, Oliveira MM, Melo T, Domingues MR, Moreira PI, Ferreiro E, Peixoto F, Videira RA. Cardiolipin profile changes are associated to the early synaptic mitochondrial dysfunction in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 43: 1375-92. PMID 25182746 DOI: 10.3233/JAD-141002 |
0.444 |
|
| 2015 |
Plácido AI, Oliveira CR, Moreira PI, Pereira CM. Enhanced amyloidogenic processing of amyloid precursor protein and cell death under prolonged endoplasmic reticulum stress in brain endothelial cells. Molecular Neurobiology. 51: 571-90. PMID 25128025 DOI: 10.1007/s12035-014-8819-1 |
0.451 |
|
| 2015 |
Fonseca AC, Moreira PI, Oliveira CR, Cardoso SM, Pinton P, Pereira CF. Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells. Molecular Neurobiology. 51: 610-22. PMID 24833600 DOI: 10.1007/S12035-014-8740-7 |
0.466 |
|
| 2015 |
Carvalho C, Correia SC, Cardoso S, Plácido AI, Candeias E, Duarte AI, Moreira PI. The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases Expert Review of Neurotherapeutics. 15: 867-884. DOI: 10.1586/14737175.2015.1058160 |
0.725 |
|
| 2015 |
Silva B, Alves M, Nunes A, Dias T, Moreira P, Oliveira P. White tea (Camellia sinensis) consumption improves heart and brain glycolytic and oxidative profiles in prediabetic rats Planta Medica. 81. DOI: 10.1055/S-0035-1565707 |
0.353 |
|
| 2015 |
Perry G, Perry EA, Moreira PI, Correia SS, Castellani RJ, Wang X, Lee H, Zhu X. P3-029: Oxidative damage is correlated with mitochondrial autophagy Alzheimer's & Dementia. 11: P630-P630. DOI: 10.1016/J.Jalz.2015.06.895 |
0.636 |
|
| 2015 |
Correia SC, Moreira PI, Perry G. Autophagy in alzheimer’s disease: A cleaning service out-of-order? Toxicity and Autophagy in Neurodegenerative Disorders. 123-142. DOI: 10.1007/978-3-319-13939-5_7 |
0.746 |
|
| 2014 |
Nunes AR, Alves MG, Moreira PI, Oliveira PF, Silva BM. Can Tea Consumption be a Safe and Effective Therapy Against Diabetes Mellitus-Induced Neurodegeneration? Current Neuropharmacology. 12: 475-89. PMID 25977676 DOI: 10.2174/1570159X13666141204220539 |
0.442 |
|
| 2014 |
Moreira PI. Metformin in the diabetic brain: friend or foe? Annals of Translational Medicine. 2: 54. PMID 25333029 DOI: 10.3978/j.issn.2305-5839.2014.06.10 |
0.322 |
|
| 2014 |
Carvalho C, Correia SC, Santos MS, Baldeiras I, Oliveira CR, Seica R, Moreira PI. Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes. Current Neurovascular Research. 11: 330-9. PMID 25182811 DOI: 10.2174/1567202611666140903122801 |
0.663 |
|
| 2014 |
Sebastião I, Candeias E, Santos MS, de Oliveira CR, Moreira PI, Duarte AI. Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease - How Anti-Diabetics Could be a Solution for Dementia. Frontiers in Endocrinology. 5: 110. PMID 25071725 DOI: 10.3389/fendo.2014.00110 |
0.721 |
|
| 2014 |
Santos RX, Correia SC, Alves MG, Oliveira PF, Cardoso S, Carvalho C, Seiça R, Santos MS, Moreira PI. Mitochondrial quality control systems sustain brain mitochondrial bioenergetics in early stages of type 2 diabetes. Molecular and Cellular Biochemistry. 394: 13-22. PMID 24833464 DOI: 10.1007/S11010-014-2076-5 |
0.8 |
|
| 2014 |
Plácido AI, Pereira CM, Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Oliveira CR, Moreira PI. The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: implications for Alzheimer's disease. Biochimica Et Biophysica Acta. 1842: 1444-53. PMID 24832819 DOI: 10.1016/J.Bbadis.2014.05.003 |
0.807 |
|
| 2014 |
Cardoso S, Carvalho C, Marinho R, Simões A, Sena CM, Matafome P, Santos MS, Seiça RM, Moreira PI. Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status. Journal of Bioenergetics and Biomembranes. 46: 347-55. PMID 24831520 DOI: 10.1007/s10863-014-9551-2 |
0.404 |
|
| 2014 |
Santos RX, Correia SC, Alves MG, Oliveira PF, Cardoso S, Carvalho C, Duarte AI, Santos MS, Moreira PI. Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats. Biochimica Et Biophysica Acta. 1842: 1154-66. PMID 24747740 DOI: 10.1016/J.Bbadis.2014.04.011 |
0.778 |
|
| 2014 |
Rato L, Duarte AI, Tomás GD, Santos MS, Moreira PI, Socorro S, Cavaco JE, Alves MG, Oliveira PF. Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress. Biochimica Et Biophysica Acta. 1837: 335-44. PMID 24361842 DOI: 10.1016/j.bbabio.2013.12.008 |
0.423 |
|
| 2014 |
Carvalho C, Katz PS, Dutta S, Katakam PV, Moreira PI, Busija DW. Increased susceptibility to amyloid-β toxicity in rat brain microvascular endothelial cells under hyperglycemic conditions. Journal of Alzheimer's Disease : Jad. 38: 75-83. PMID 23948922 DOI: 10.3233/JAD-130464 |
0.402 |
|
| 2014 |
Correia SC, Santos MS, Moreira PI. S2.P5Adaptive reprogramming of brain mitochondrial biology during preconditioning prevents the sporadic Alzheimer's disease-like phenotype Biochimica Et Biophysica Acta. 1837. DOI: 10.1016/J.Bbabio.2014.05.293 |
0.742 |
|
| 2014 |
Rato L, Duarte AI, Tomás GD, Santos MS, Moreira PI, Socorro S, Cavaco JE, Alves MG, Oliveira PF. Pre-diabetes disrupts testicular PGC1-α/SIRT3 axis prompting oxidative stress Biochimica Et Biophysica Acta. 1837. DOI: 10.1016/J.Bbabio.2014.05.243 |
0.301 |
|
| 2014 |
Moreira PI. Mitochondria take center stage in Alzheimer's disease Biochimica Et Biophysica Acta. 1837. DOI: 10.1016/J.Bbabio.2014.05.134 |
0.462 |
|
| 2014 |
Castellani RJ, Zhu X, Perry G, Moreira PI. Alzheimer's Disease: An Overview Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.04491-3 |
0.668 |
|
| 2014 |
Castellani RJ, Moreira PI, Zhu X, Perry G. Alzheimer's Disease: Pathology and Pathogenesis Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00160-4 |
0.679 |
|
| 2014 |
Santos RX, Moreira PI. Mtor is a potential therapeutic target for alzheimer's disease Advances in Cognitive and Behavioral Sciences. 183-207. |
0.696 |
|
| 2013 |
Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? Journal of Neurochemistry. 127: 4-6. PMID 24074055 DOI: 10.1111/Jnc.12406 |
0.742 |
|
| 2013 |
Mondragón-RodrÃguez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease. Oxidative Medicine and Cellular Longevity. 2013: 940603. PMID 23936615 DOI: 10.1155/2013/940603 |
0.623 |
|
| 2013 |
González-Burgos E, Duarte AI, Carretero ME, Moreira PI, Gómez-Serranillos MP. Mitochondrial-targeted protective properties of isolated diterpenoids from sideritis spp. in response to the deleterious changes induced by H2O2. Journal of Natural Products. 76: 933-8. PMID 23675610 DOI: 10.1021/np400118d |
0.449 |
|
| 2013 |
Moreira PI. High-sugar diets, type 2 diabetes and Alzheimer's disease. Current Opinion in Clinical Nutrition and Metabolic Care. 16: 440-5. PMID 23657152 DOI: 10.1097/MCO.0b013e328361c7d1 |
0.437 |
|
| 2013 |
Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radical Research. 47: 507-10. PMID 23566300 DOI: 10.3109/10715762.2013.794265 |
0.769 |
|
| 2013 |
Correia SC, Carvalho C, Cardoso S, Santos RX, Plácido AI, Candeias E, Duarte AI, Moreira PI. Defective HIF signaling pathway and brain response to hypoxia in neurodegenerative diseases: not an "iffy" question! Current Pharmaceutical Design. 19: 6809-22. PMID 23530518 DOI: 10.2174/1381612811319380013 |
0.8 |
|
| 2013 |
Cardoso S, Santos MS, Moreno A, Moreira PI. UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats. Journal of Bioenergetics and Biomembranes. 45: 397-407. PMID 23504111 DOI: 10.1007/s10863-013-9503-2 |
0.358 |
|
| 2013 |
Carvalho C, Machado N, Mota PC, Correia SC, Cardoso S, Santos RX, Santos MS, Oliveira CR, Moreira PI. Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies. Journal of Alzheimer's Disease : Jad. 35: 623-35. PMID 23478310 DOI: 10.3233/Jad-130005 |
0.786 |
|
| 2013 |
Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Plácido A, Santos MS, Oliveira CR, Moreira PI. Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration. Biochimica Et Biophysica Acta. 1832: 527-41. PMID 23314196 DOI: 10.1016/J.Bbadis.2013.01.008 |
0.801 |
|
| 2013 |
Moreno AJ, Moreira PI, Custódio JB, Santos MS. Mechanism of inhibition of mitochondrial ATP synthase by 17β-estradiol. Journal of Bioenergetics and Biomembranes. 45: 261-70. PMID 23274738 DOI: 10.1007/s10863-012-9497-1 |
0.307 |
|
| 2013 |
Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxidants & Redox Signaling. 18: 2444-57. PMID 23216311 DOI: 10.1089/Ars.2012.5039 |
0.838 |
|
| 2013 |
Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Current Alzheimer Research. 10: 406-19. PMID 23061885 DOI: 10.2174/1567205011310040006 |
0.822 |
|
| 2013 |
Cardoso S, Santos RX, Correia SC, Carvalho C, Santos MS, Baldeiras I, Oliveira CR, Moreira PI. Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance. Neurobiology of Disease. 49: 1-12. PMID 22940631 DOI: 10.1016/J.Nbd.2012.08.008 |
0.798 |
|
| 2013 |
Cardoso S, Correia SC, Santos RX, Carvalho C, Candeias E, Duarte AI, Plácido AI, Santos MS, Moreira PI. Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins. Current Molecular Medicine. 13: 586-601. PMID 22934852 DOI: 10.2174/1566524011313040010 |
0.822 |
|
| 2013 |
Carvalho C, Santos RX, Cardoso S, Correia SC, Moreira PI. Chronic hypoxia, type 2 diabetes and Alzheimer's disease: A dangerous triad Hypoxia: Causes, Types and Management. 21-34. |
0.775 |
|
| 2012 |
Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Plácido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. Iubmb Life. 64: 951-7. PMID 23129399 DOI: 10.1002/Iub.1098 |
0.81 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Moreira PI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.561 |
|
| 2012 |
Marques-Aleixo I, Oliveira PJ, Moreira PI, Magalhães J, Ascensão A. Physical exercise as a possible strategy for brain protection: evidence from mitochondrial-mediated mechanisms. Progress in Neurobiology. 99: 149-62. PMID 22940590 DOI: 10.1016/j.pneurobio.2012.08.002 |
0.441 |
|
| 2012 |
Alves MG, Oliveira PF, Socorro S, Moreira PI. Impact of diabetes in blood-testis and blood-brain barriers: resemblances and differences. Current Diabetes Reviews. 8: 401-12. PMID 22934551 DOI: 10.2174/157339912803529896 |
0.307 |
|
| 2012 |
Correia SC, Santos RX, Cardoso S, Carvalho C, Candeias E, Duarte AI, Plácido AI, Santos MS, Moreira PI. Alzheimer disease as a vascular disorder: where do mitochondria fit? Experimental Gerontology. 47: 878-86. PMID 22824543 DOI: 10.1016/J.Exger.2012.07.006 |
0.831 |
|
| 2012 |
Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Williams S. Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target? International Journal of Alzheimer's Disease. 2012: 276803. PMID 22779025 DOI: 10.1155/2012/276803 |
0.796 |
|
| 2012 |
Nunomura A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotoxicity Research. 22: 231-48. PMID 22669748 DOI: 10.1007/s12640-012-9331-x |
0.778 |
|
| 2012 |
Duarte AI, Moreira PI, Oliveira CR. Insulin in central nervous system: more than just a peripheral hormone. Journal of Aging Research. 2012: 384017. PMID 22500228 DOI: 10.1155/2012/384017 |
0.378 |
|
| 2012 |
Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors (Oxford, England). 38: 133-8. PMID 22447715 DOI: 10.1002/biof.1010 |
0.683 |
|
| 2012 |
Carvalho C, Cardoso S, Correia SC, Santos RX, Santos MS, Baldeiras I, Oliveira CR, Moreira PI. Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities. Diabetes. 61: 1234-42. PMID 22427376 DOI: 10.2337/Db11-1186 |
0.823 |
|
| 2012 |
Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases. Advances in Experimental Medicine and Biology. 724: 205-21. PMID 22411245 DOI: 10.1007/978-1-4614-0653-2_16 |
0.843 |
|
| 2012 |
Correia SC, Santos RX, Carvalho C, Cardoso S, Candeias E, Santos MS, Oliveira CR, Moreira PI. Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation. Brain Research. 1441: 64-78. PMID 22290178 DOI: 10.1016/J.Brainres.2011.12.063 |
0.81 |
|
| 2012 |
Moreira PI. Alzheimer's disease and diabetes: an integrative view of the role of mitochondria, oxidative stress, and insulin. Journal of Alzheimer's Disease : Jad. 30: S199-215. PMID 22269163 DOI: 10.3233/JAD-2011-111127 |
0.461 |
|
| 2012 |
Santos RX, Correia SC, Zhu X, Lee HG, Petersen RB, Nunomura A, Smith MA, Perry G, Moreira PI. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease. Free Radical Research. 46: 565-76. PMID 22149654 DOI: 10.3109/10715762.2011.648188 |
0.833 |
|
| 2012 |
Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radical Biology & Medicine. 52: 699-704. PMID 22137893 DOI: 10.1016/J.Freeradbiomed.2011.11.004 |
0.823 |
|
| 2012 |
Correia SC, Santos RX, Cardoso SM, Santos MS, Oliveira CR, Moreira PI. Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α. Neurobiology of Disease. 45: 206-18. PMID 21854848 DOI: 10.1016/J.Nbd.2011.08.005 |
0.794 |
|
| 2012 |
Perry EA, Castellani R, Moreira P, GeorgePerry. A New Age in Metabolism Metabolomics. 2. DOI: 10.4172/2153-0769.1000E118 |
0.497 |
|
| 2011 |
Liu Q, Xie F, Alvarado-Diaz A, Smith MA, Moreira PI, Zhu X, Perry G. Neurofilamentopathy in neurodegenerative diseases. The Open Neurology Journal. 5: 58-62. PMID 21915226 DOI: 10.2174/1874205X01105010058 |
0.719 |
|
| 2011 |
Correia SC, Cardoso S, Santos RX, Carvalho C, Santos MS, Perry G, Smith MA, Moreira PI. New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection. Current Pharmaceutical Design. 17: 3381-9. PMID 21902670 DOI: 10.2174/138161211798072490 |
0.819 |
|
| 2011 |
Moreira PI, Oliveira CR. Mitochondria as potential targets in antidiabetic therapy. Handbook of Experimental Pharmacology. 331-56. PMID 21484578 DOI: 10.1007/978-3-642-17214-4_14 |
0.383 |
|
| 2011 |
Santos RX, Correia SC, Cardoso S, Carvalho C, Santos MS, Moreira PI. Effects of rapamycin and TOR on aging and memory: implications for Alzheimer's disease. Journal of Neurochemistry. 117: 927-36. PMID 21447003 DOI: 10.1111/J.1471-4159.2011.07262.X |
0.779 |
|
| 2011 |
Santos RX, Correia SC, Carvalho C, Cardoso S, Santos MS, Moreira PI. Mitophagy in neurodegeneration: an opportunity for therapy? Current Drug Targets. 12: 790-9. PMID 21269269 DOI: 10.2174/138945011795528813 |
0.829 |
|
| 2011 |
Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Research Reviews. 10: 264-73. PMID 21262392 DOI: 10.1016/J.Arr.2011.01.001 |
0.808 |
|
| 2011 |
Moreira PI, Custódio JB, Nunes E, Oliveira PJ, Moreno A, Seiça R, Oliveira CR, Santos MS. Mitochondria from distinct tissues are differently affected by 17β-estradiol and tamoxifen. The Journal of Steroid Biochemistry and Molecular Biology. 123: 8-16. PMID 20932907 DOI: 10.1016/j.jsbmb.2010.09.004 |
0.326 |
|
| 2011 |
Cardoso S, Carvalho C, Santos R, Correia S, Santos MS, Seiça R, Oliveira CR, Moreira PI. Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters. Synapse (New York, N.Y.). 65: 457-66. PMID 20853444 DOI: 10.1002/Syn.20863 |
0.745 |
|
| 2011 |
Cardoso S, Santos RX, Carvalho C, Correia S, Santos MS, Moreira PI. Mitochondrial Uncoupling Proteins and Oxidative Stress: Implications for Diabetes and Neurodegeneration Free Radicals and Antioxidants. 1: 4-14. DOI: 10.5530/Ax.2011.2.3 |
0.82 |
|
| 2011 |
Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Zhu X, Smith MA, Perry G. Association of mitochondrial signaling in Alzheimer's disease and hypoxia Molecular Aspects of Neurodegeneration and Neuroprotection. 50-61. DOI: 10.2174/978160805092511101010050 |
0.825 |
|
| 2011 |
Correia S, Casadesus G, LaManna J, Perry G, Zhu X, Smith M, Moreira P. P3-290: Neuroprotective effects of hypoxic preconditioning on streptozotocin-induced animal model of sporadic Alzheimer's disease Alzheimer's & Dementia. 7: S609-S609. DOI: 10.1016/J.Jalz.2011.05.1732 |
0.766 |
|
| 2011 |
Correia S, Perry G, Zhu X, Smith M, Moreira P. P3-146: Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease Alzheimer's & Dementia. 7: S562-S562. DOI: 10.1016/J.Jalz.2011.05.1586 |
0.786 |
|
| 2011 |
Collins GH, Mondragón-Rodríguez S, Nunomura A, Zhu X, Moreira PI, Smith MA. Oxidative Stress and Balance in Neurodegenerative Diseases Neurodegeneration: the Molecular Pathology of Dementia and Movement Disorders: Second Edition. 10-12. DOI: 10.1002/9781444341256.ch3 |
0.825 |
|
| 2011 |
Carvalho C, Correia SC, Santos RX, Cardoso S, Santos MS, Moreira PI. Diabetes, mitochondria and brain endothelium dysfunction: A dangerous triad for neurodegeneration? Mitochondria: Structure, Functions and Dysfunctions. 553-577. |
0.759 |
|
| 2011 |
Cardoso S, Carvalho C, Correia S, Santos RX, Santos MS, Moreira PI. Mitochondrial uncoupling proteins - therapeutic targets in neurodegeneration? Neurodegeneration: Theory, Disorders and Treatments. 107-124. |
0.769 |
|
| 2010 |
Carvalho C, Santos MS, Baldeiras I, Oliveira CR, Seiça R, Moreira PI. Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes. Current Neurovascular Research. 7: 288-300. PMID 20854250 DOI: 10.2174/156720210793180765 |
0.361 |
|
| 2010 |
Correia SC, Carvalho C, Cardoso S, Santos RX, Santos MS, Oliveira CR, Perry G, Zhu X, Smith MA, Moreira PI. Mitochondrial preconditioning: a potential neuroprotective strategy. Frontiers in Aging Neuroscience. 2. PMID 20838473 DOI: 10.3389/Fnagi.2010.00138 |
0.834 |
|
| 2010 |
Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. International Journal of Clinical and Experimental Pathology. 3: 570-81. PMID 20661404 |
0.849 |
|
| 2010 |
Cardoso S, Santos MS, Seiça R, Moreira PI. Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. Biochimica Et Biophysica Acta. 1802: 942-51. PMID 20620209 DOI: 10.1016/j.bbadis.2010.07.001 |
0.348 |
|
| 2010 |
Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy in Alzheimer's disease. Expert Review of Neurotherapeutics. 10: 1209-18. PMID 20586699 DOI: 10.1586/Ern.10.84 |
0.852 |
|
| 2010 |
Santos RX, Cardoso S, Correia S, Carvalho C, Santos MS, Moreira PI. Targeting autophagy in the brain: a promising approach? Central Nervous System Agents in Medicinal Chemistry. 10: 158-68. PMID 20518730 DOI: 10.2174/187152410791196350 |
0.81 |
|
| 2010 |
Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missing link between preconditioning and neuroprotection. Journal of Alzheimer's Disease : Jad. 20: S475-85. PMID 20463394 DOI: 10.3233/Jad-2010-100669 |
0.817 |
|
| 2010 |
Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 20: S401-12. PMID 20463393 DOI: 10.3233/Jad-2010-100666 |
0.849 |
|
| 2010 |
Correia SC, Santos RX, Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI. Effects of estrogen in the brain: is it a neuroprotective agent in Alzheimer's disease? Current Aging Science. 3: 113-26. PMID 20167003 DOI: 10.2174/1874609811003020113 |
0.801 |
|
| 2010 |
Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods in Molecular Biology (Clifton, N.J.). 610: 419-34. PMID 20013193 DOI: 10.1007/978-1-60327-029-8_25 |
0.743 |
|
| 2010 |
Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochimica Et Biophysica Acta. 1802: 2-10. PMID 19853658 DOI: 10.1016/j.bbadis.2009.10.006 |
0.729 |
|
| 2010 |
Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA. Mitochondria: a therapeutic target in neurodegeneration. Biochimica Et Biophysica Acta. 1802: 212-20. PMID 19853657 DOI: 10.1016/J.Bbadis.2009.10.007 |
0.816 |
|
| 2010 |
Correia SC, Moreira PI. Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration? Journal of Neurochemistry. 112: 1-12. PMID 19845827 DOI: 10.1111/J.1471-4159.2009.06443.X |
0.699 |
|
| 2010 |
Cardoso SM, Pereira CF, Moreira PI, Arduino DM, Esteves AR, Oliveira CR. Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease. Experimental Neurology. 223: 294-8. PMID 19559703 DOI: 10.1016/J.Expneurol.2009.06.008 |
0.542 |
|
| 2010 |
Moreira PI. Mitochondrial dysfunction and oxidative stress in Alzheimer's disease European Neurological Review. 5: 17-21. DOI: 10.17925/Enr.2010.05.01.17 |
0.46 |
|
| 2010 |
Castellani R, Moreira P, Aliev G, Shenk J, Siedlak S, Harris P, Sayre L, Szweda L, Zhu X, Smith M, Perry G, Szweda P. Hydroxynonenal-Generated Crosslinking Fluorophore and Mitochondria-derived Lipoic Acid Accumulation in Alzheimer Disease Reveal a Dichotomy of Protein Turnover Microscopy and Microanalysis. 16: 1014-1015. DOI: 10.1017/S1431927610059350 |
0.82 |
|
| 2010 |
Shenk JC, Smith MA, Castellani RJ, Moreira P, Aliev G, Siedlak SL, Harris PL, Sayre L, Szweda PA, Szweda LI, Perry G. P1-196: Lipid peroxidation markers are associated with granulovacuolar degeneration but not lipofuscin formation Alzheimer's & Dementia. 6: S230-S230. DOI: 10.1016/J.Jalz.2010.05.746 |
0.764 |
|
| 2010 |
Correia SC, Santos RX, Santos MS, Moreira PI. Mitochondrial reactive oxygen species preconditioning protects brain cells against hyperglycemia Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1901 |
0.781 |
|
| 2010 |
Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI. Mitochondrial dysfunction and oxidative status impairment: A comparative study between male and female 3xTg-AD mice Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1306 |
0.395 |
|
| 2010 |
Carvalho C, Santos MS, Oliveira C, Moreira P. Insulin resistance induced by sucrose intake exacerbates brain mitochondrial dysfunction in a mouse model of Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1303 |
0.467 |
|
| 2009 |
Cardoso S, Santos R, Correia S, Carvalho C, Zhu X, Lee HG, Casadesus G, Smith MA, Perry G, Moreira PI. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets. Pharmaceuticals (Basel, Switzerland). 2: 250-286. PMID 27713238 DOI: 10.3390/Ph2030250 |
0.804 |
|
| 2009 |
Perry G, Moreira PI, Siedlak SL, Nunomura A, Zhu X, Smith MA. Natural oxidant balance in Parkinson disease. Archives of Neurology. 66: 1445. PMID 20008647 DOI: 10.1001/Archneurol.2009.261 |
0.754 |
|
| 2009 |
Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. Journal of Bioenergetics and Biomembranes. 41: 433-40. PMID 19830532 DOI: 10.1007/S10863-009-9247-1 |
0.848 |
|
| 2009 |
Moreira PI, Cardoso SM, Pereira CM, Santos MS, Oliveira CR. Mitochondria as a therapeutic target in Alzheimer's disease and diabetes. Cns & Neurological Disorders Drug Targets. 8: 492-511. PMID 19702564 DOI: 10.2174/187152709789824651 |
0.472 |
|
| 2009 |
Carvalho C, Santos RX, Cardoso S, Correia S, Oliveira PJ, Santos MS, Moreira PI. Doxorubicin: the good, the bad and the ugly effect. Current Medicinal Chemistry. 16: 3267-85. PMID 19548866 DOI: 10.2174/092986709788803312 |
0.745 |
|
| 2009 |
Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. Journal of Alzheimer's Disease : Jad. 18: 483-507. PMID 19542630 DOI: 10.3233/Jad-2009-1155 |
0.792 |
|
| 2009 |
Moreira PI, Duarte AI, Santos MS, Rego AC, Oliveira CR. An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 16: 741-61. PMID 19387110 DOI: 10.3233/JAD-2009-0972 |
0.528 |
|
| 2009 |
Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathologica. 118: 151-66. PMID 19271225 DOI: 10.1007/s00401-009-0508-1 |
0.777 |
|
| 2009 |
Perry G, Zhu X, Moreira PI, Smith MA. Altered redox balance in disease: can we change the new equilibria? Annals of Neurology. 65: 121-3. PMID 19259960 DOI: 10.1002/ana.21608 |
0.627 |
|
| 2009 |
Santos RX, Cardoso S, Silva S, Correia S, Carvalho C, Crisóstomo J, Rodrigues L, Amaral C, Louro T, Matafome P, Santos MS, Proença T, Duarte AI, Seiça R, Moreira PI. Food deprivation promotes oxidative imbalance in rat brain. Journal of Food Science. 74: H8-H14. PMID 19200099 DOI: 10.1111/J.1750-3841.2008.00982.X |
0.762 |
|
| 2009 |
Friedlich AL, Smith MA, Zhu X, Takeda A, Nunomura A, Moreira PI, Perry G. Oxidative Stress in Parkinson`s Disease The Open Pathology Journal. 3: 38-42. DOI: 10.2174/1874375700903010038 |
0.825 |
|
| 2009 |
Moreira PI, Santos MS, Seiça R, Oliveira CR. Diabetes is a risk factor for Alzheimer disease: The role of mitochondria Journal of the Neurological Sciences. 283: 271. DOI: 10.1016/J.Jns.2009.02.123 |
0.404 |
|
| 2009 |
Shenk JC, Castellani RJ, Moreira P, Aliev G, Siedlak SL, Harris PL, Sayre L, Szweda PA, Smith MA, Perry G. P2-186: Hydroxynonenal generated crosslinking fluorophores accumulate in Alzheimer's disease Alzheimer's & Dementia. 5: P315-P315. DOI: 10.1016/J.Jalz.2009.04.498 |
0.823 |
|
| 2009 |
Nunomura A, Takeda A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Neurofibrillary tangle formation as a protective response to oxidative stress in Alzheimer's disease Current Hypotheses and Research Milestones in Alzheimer's Disease. 103-113. DOI: 10.1007/978-0-387-87995-6_9 |
0.767 |
|
| 2009 |
Marlatt MW, Moreira PI, Lee Hg, Casadesus G, Castellani RJ, Takeda A, Nunomura A, Zhu X, Perry G, Smith MA. Therapeutic opportunities in Alzheimer disease: Current concepts Frontiers in Medicinal Chemistry. 4: 767-788. |
0.786 |
|
| 2008 |
Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. International Journal of Molecular Sciences. 9: 789-806. PMID 19325784 DOI: 10.3390/Ijms9050789 |
0.791 |
|
| 2008 |
Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X. Oxidative stress signaling in Alzheimer's disease. Current Alzheimer Research. 5: 525-32. PMID 19075578 DOI: 10.2174/156720508786898451 |
0.806 |
|
| 2008 |
Wang X, Su B, Siedlak SL, Moreira PI, Fujioka H, Wang Y, Casadesus G, Zhu X. Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proceedings of the National Academy of Sciences of the United States of America. 105: 19318-23. PMID 19050078 DOI: 10.1073/Pnas.0804871105 |
0.723 |
|
| 2008 |
Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Reviews in Medicinal Chemistry. 8: 1395-406. PMID 18991755 DOI: 10.2174/138955708786369582 |
0.831 |
|
| 2008 |
Correia S, Carvalho C, Santos MS, Seiça R, Oliveira CR, Moreira PI. Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview. Mini Reviews in Medicinal Chemistry. 8: 1343-54. PMID 18991752 DOI: 10.2174/138955708786369546 |
0.613 |
|
| 2008 |
Perry G, Castellani RJ, Moreira PI, Lee HG, Zhu X, Smith MA. Pathology's new role: defining disease process and protective responses. International Journal of Clinical and Experimental Pathology. 1: 1-4. PMID 18784818 |
0.705 |
|
| 2008 |
Cardoso S, Santos RX, Carvalho C, Correia S, Pereira GC, Pereira SS, Oliveira PJ, Santos MS, Proença T, Moreira PI. Doxorubicin increases the susceptibility of brain mitochondria to Ca(2+)-induced permeability transition and oxidative damage. Free Radical Biology & Medicine. 45: 1395-402. PMID 18775776 DOI: 10.1016/J.Freeradbiomed.2008.08.008 |
0.796 |
|
| 2008 |
Correia S, Carvalho C, Santos MS, Proença T, Nunes E, Duarte AI, Monteiro P, Seiça R, Oliveira CR, Moreira PI. Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes. Medicinal Chemistry (ShäRiqah (United Arab Emirates)). 4: 358-64. PMID 18673148 DOI: 10.2174/157340608784872299 |
0.658 |
|
| 2008 |
Resende R, Moreira PI, Proença T, Deshpande A, Busciglio J, Pereira C, Oliveira CR. Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease. Free Radical Biology & Medicine. 44: 2051-7. PMID 18423383 DOI: 10.1016/J.Freeradbiomed.2008.03.012 |
0.504 |
|
| 2008 |
Moreira PI, Santos MS, Oliveira CR, Shenk JC, Nunomura A, Smith MA, Zhu X, Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. Cns & Neurological Disorders Drug Targets. 7: 3-10. PMID 18289026 DOI: 10.2174/187152708783885156 |
0.855 |
|
| 2008 |
Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radical Biology & Medicine. 44: 1493-505. PMID 18258207 DOI: 10.1016/J.Freeradbiomed.2008.01.002 |
0.838 |
|
| 2008 |
Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, ... ... Moreira PI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003 DOI: 10.4161/Auto.5338 |
0.636 |
|
| 2008 |
Carvalho C, Correia S, Santos MS, Seiça R, Oliveira CR, Moreira PI. Metformin promotes isolated rat liver mitochondria impairment. Molecular and Cellular Biochemistry. 308: 75-83. PMID 17909944 DOI: 10.1007/S11010-007-9614-3 |
0.678 |
|
| 2008 |
Moreira PI, Santos MS, Siedlak SL, Harris P, Smith MA, Aliev G, Perry G, Oliveira CR. P4-185: Mitochondrial dysfunction in Alzheimer's disease Alzheimer's & Dementia. 4: T725-T725. DOI: 10.1016/J.Jalz.2008.05.2252 |
0.759 |
|
| 2008 |
Resende R, Moreira PI, Deshpande A, Busciglio J, Pereira C, Oliveira CR. P4-183: Increased oxidative stress is an early pathological feature in 3xTg-AD mice Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.2250 |
0.383 |
|
| 2007 |
Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. Cns & Neurological Disorders Drug Targets. 6: 411-23. PMID 18220780 DOI: 10.2174/187152707783399201 |
0.817 |
|
| 2007 |
Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Current Medicinal Chemistry. 14: 2968-75. PMID 18220733 DOI: 10.2174/092986707782794078 |
0.736 |
|
| 2007 |
Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. Journal of Alzheimer's Disease : Jad. 12: 195-206. PMID 17917164 DOI: 10.3233/Jad-2007-12210 |
0.673 |
|
| 2007 |
Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy. 3: 614-5. PMID 17786024 DOI: 10.4161/Auto.4872 |
0.864 |
|
| 2007 |
Moreira PI, Santos MS, Oliveira CR. Alzheimer's disease: a lesson from mitochondrial dysfunction. Antioxidants & Redox Signaling. 9: 1621-30. PMID 17678440 DOI: 10.1089/ars.2007.1703 |
0.554 |
|
| 2007 |
Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 66: 525-32. PMID 17549012 DOI: 10.1016/J.Jns.2009.02.162 |
0.848 |
|
| 2007 |
Castellani RJ, Moreira PI, Liu G, Dobson J, Perry G, Smith MA, Zhu X. Iron: the Redox-active center of oxidative stress in Alzheimer disease. Neurochemical Research. 32: 1640-5. PMID 17508283 DOI: 10.1007/S11064-007-9360-7 |
0.761 |
|
| 2007 |
Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Review of Neurotherapeutics. 7: 473-85. PMID 17492899 DOI: 10.1586/14737175.7.5.473 |
0.727 |
|
| 2007 |
Moreira PI, Custódio JB, Nunes E, Moreno A, Seiça R, Oliveira CR, Santos MS. Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats. Toxicology and Applied Pharmacology. 221: 102-10. PMID 17397887 DOI: 10.1016/j.taap.2007.02.006 |
0.38 |
|
| 2007 |
Casadesus G, Moreira PI, Nunomura A, Siedlak SL, Bligh-Glover W, Balraj E, Petot G, Smith MA, Perry G. Indices of metabolic dysfunction and oxidative stress. Neurochemical Research. 32: 717-22. PMID 17342408 DOI: 10.1007/S11064-007-9296-Y |
0.827 |
|
| 2007 |
Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. Journal of the Neurological Sciences. 257: 240-6. PMID 17337008 DOI: 10.1016/J.Jns.2007.01.039 |
0.847 |
|
| 2007 |
Moreira PI, Santos MS, Seiça R, Oliveira CR. Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes. Journal of the Neurological Sciences. 257: 206-14. PMID 17316694 DOI: 10.1016/j.jns.2007.01.017 |
0.534 |
|
| 2007 |
Liu Q, Xie F, Rolston R, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Reviews in Medicinal Chemistry. 7: 171-80. PMID 17305591 DOI: 10.2174/138955707779802552 |
0.802 |
|
| 2007 |
Perry G, Moreira PI, Siedlak SL, Santos MS, Oliveira CR, Fujioka H, Tabaton M, Nunomura A, Aliev G, Szweda LI, Smith MA. Mitochondrial autophagocytosis in Alzheimer disease Journal of Neuropathology and Experimental Neurology. 66: 434. DOI: 10.1097/01.Jnen.0000268871.37441.1B |
0.848 |
|
| 2007 |
Perry G, Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA. Lipoic acid and N-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients Journal of Neuropathology and Experimental Neurology. 66: 434. DOI: 10.1097/01.Jnen.0000268870.37441.52 |
0.693 |
|
| 2007 |
Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Erratum: Autophagocytosis of mitochondria is prominent in Alzheimer disease (Journal of Neuropathology and Experimental Neurology (2007) 66, (525-532)) Journal of Neuropathology and Experimental Neurology. 66. DOI: 10.1097/01.Jnen.0000263876.99435.Cb |
0.825 |
|
| 2007 |
Moreira PI, Nunomura A, Honda K, Aliev G, Casadesus G, Zhu X, Smith MA, Perry G. The key role of oxidative stress in alzheimer's disease Oxidative Stress and Neurodegenerative Disorders. 267-281. DOI: 10.1016/B978-044452809-4/50153-8 |
0.837 |
|
| 2007 |
Moreira PI, Smith MA, Zhu X, Nunomura A, Perry G. The potential application of antioxidant agents in Alzheimer disease therapeutics Pharmacological Mechanisms in Alzheimer's Therapeutics. 194-211. DOI: 10.1007/978-0-387-71522-3_12 |
0.736 |
|
| 2006 |
Franco S, Blasco MA, Siedlak SL, Harris PL, Moreira PI, Perry G, Smith MA. Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 164-8. PMID 19595878 DOI: 10.1016/J.Jalz.2006.03.001 |
0.67 |
|
| 2006 |
Moreira PI, Rolo AP, Sena C, Seiça R, Oliveira CR, Santos MS. Insulin attenuates diabetes-related mitochondrial alterations: a comparative study. Medicinal Chemistry (ShäRiqah (United Arab Emirates)). 2: 299-308. PMID 16948477 DOI: 10.2174/157340606776930754 |
0.393 |
|
| 2006 |
Zhu X, Perry G, Moreira PI, Aliev G, Cash AD, Hirai K, Smith MA. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. Journal of Alzheimer's Disease : Jad. 9: 147-53. PMID 16873962 DOI: 10.3233/JAD-2006-9207 |
0.837 |
|
| 2006 |
Moreira PI, Cardoso SM, Santos MS, Oliveira CR. The key role of mitochondria in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 9: 101-10. PMID 16873957 |
0.432 |
|
| 2006 |
Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 631-41. PMID 16825950 DOI: 10.1097/01.jnen.0000228136.58062.bf |
0.821 |
|
| 2006 |
Moreira PI, Zhu X, Nunomura A, Smith MA, Perry G. Therapeutic options in Alzheimer's disease. Expert Review of Neurotherapeutics. 6: 897-910. PMID 16784412 DOI: 10.1586/14737175.6.6.897 |
0.763 |
|
| 2006 |
Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Science of Aging Knowledge Environment : Sage Ke. 2006: pe10. PMID 16672726 DOI: 10.1126/sageke.2006.8.pe10 |
0.825 |
|
| 2006 |
Moreira PI, Zhu X, Liu Q, Honda K, Siedlak SL, Harris PL, Smith MA, Perry G. Compensatory responses induced by oxidative stress in Alzheimer disease. Biological Research. 39: 7-13. PMID 16629160 DOI: 10.4067/S0716-97602006000100002 |
0.827 |
|
| 2006 |
Zhu X, Lee HG, Moreira PI, Smith MA, Perry G. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice". Free Radical Biology & Medicine. 40: 737-9. PMID 16520226 DOI: 10.1016/j.freeradbiomed.2005.12.028 |
0.626 |
|
| 2006 |
Moreira PI, Zhu X, Lee HG, Honda K, Smith MA, Perry G. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease. Mechanisms of Ageing and Development. 127: 501-6. PMID 16516950 DOI: 10.1016/j.mad.2006.01.024 |
0.799 |
|
| 2006 |
Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 66: S97-101. PMID 16432155 DOI: 10.1212/01.wnl.0000192307.15103.83 |
0.835 |
|
| 2006 |
Moreira PI, Custódio J, Moreno A, Oliveira CR, Santos MS. Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure. The Journal of Biological Chemistry. 281: 10143-52. PMID 16410252 DOI: 10.1074/jbc.M510249200 |
0.319 |
|
| 2006 |
Moreira PI, Oliveira C. Foreword: Mitochondria in Alzheimer disease Journal of Alzheimer's Disease. 9: 99. DOI: 10.3233/Jad-2006-9201 |
0.531 |
|
| 2006 |
Moreira PI, Zhu X, Lee H, Nunomura A, Smith MA, Perry G. Therapeutic potential of oxidative stress reduction in Alzheimer's disease Future Neurology. 1: 1-4. DOI: 10.2217/14796708.1.1.1 |
0.699 |
|
| 2006 |
Smith MA, Moreira PI, Castellani RJ, Perry G. Symposium Brain Pathology. 14: 425-425. DOI: 10.1111/j.1750-3639.2004.tb00086.x |
0.492 |
|
| 2006 |
Moreira PI, Siedlak SL, Santos MS, Oliveira CR, Fujioka H, Tabaton M, Nunomura A, Aliev G, Szweda LI, Zhu X, Smith MA, Perry G. O4-02-08: Mitochondrial autophagocytosis in Alzheimer disease Alzheimer's & Dementia. 2: S79-S79. DOI: 10.1016/J.Jalz.2006.05.307 |
0.829 |
|
| 2006 |
Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. P3-375: Lipoic acid and N
-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients Alzheimer's & Dementia. 2: S486-S486. DOI: 10.1016/J.Jalz.2006.05.1645 |
0.688 |
|
| 2005 |
Moreira PI, Honda K, Liu Q, Santos MS, Oliveira CR, Aliev G, Nunomura A, Zhu X, Smith MA, Perry G. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Current Alzheimer Research. 2: 403-8. PMID 16248845 DOI: 10.2174/156720505774330537 |
0.844 |
|
| 2005 |
Sayre LM, Moreira PI, Smith MA, Perry G. Metal ions and oxidative protein modification in neurological disease. Annali Dell'Istituto Superiore Di Sanitã . 41: 143-64. PMID 16244388 |
0.667 |
|
| 2005 |
Moreira PI, Oliveira CR, Santos MS, Nunomura A, Honda K, Zhu X, Smith MA, Perry G. A second look into the oxidant mechanisms in Alzheimer's disease. Current Neurovascular Research. 2: 179-84. PMID 16181112 DOI: 10.2174/1567202053586758 |
0.844 |
|
| 2005 |
Moreira PI, Santos MS, Sena C, Nunes E, Seiça R, Oliveira CR. CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats. Experimental Neurology. 196: 112-9. PMID 16126199 DOI: 10.1016/j.expneurol.2005.07.012 |
0.436 |
|
| 2005 |
Cardoso SM, Moreira PI, Agostinho P, Pereira C, Oliveira CR. Neurodegenerative pathways in Parkinson's disease: therapeutic strategies. Current Drug Targets. Cns and Neurological Disorders. 4: 405-19. PMID 16101557 DOI: 10.2174/1568007054546072 |
0.379 |
|
| 2005 |
Pereira C, Agostinho P, Moreira PI, Cardoso SM, Oliveira CR. Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies. Current Drug Targets. Cns and Neurological Disorders. 4: 383-403. PMID 16101556 DOI: 10.2174/1568007054546117 |
0.451 |
|
| 2005 |
Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, et al. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathologica. 110: 232-8. PMID 16096758 DOI: 10.1007/S00401-005-1034-4 |
0.839 |
|
| 2005 |
Zhu X, Moreira PI, Smith MA, Perry G. Alzheimer's disease: an intracellular movement disorder? Trends in Molecular Medicine. 11: 391-3. PMID 16087404 DOI: 10.1016/j.molmed.2005.07.002 |
0.617 |
|
| 2005 |
Moreira PI, Smith MA, Zhu X, Nunomura A, Castellani RJ, Perry G. Oxidative stress and neurodegeneration. Annals of the New York Academy of Sciences. 1043: 545-52. PMID 16037277 DOI: 10.1196/annals.1333.062 |
0.817 |
|
| 2005 |
Marlatt MW, Webber KM, Moreira PI, Lee HG, Casadesus G, Honda K, Zhu X, Perry G, Smith MA. Therapeutic opportunities in Alzheimer disease: one for all or all for one? Current Medicinal Chemistry. 12: 1137-47. PMID 15892629 DOI: 10.2174/0929867053764644 |
0.827 |
|
| 2005 |
Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends in Molecular Medicine. 11: 164-9. PMID 15823754 DOI: 10.1016/J.Molmed.2005.02.008 |
0.801 |
|
| 2005 |
Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, et al. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. The Journal of Biological Chemistry. 280: 20978-86. PMID 15767256 DOI: 10.1074/Jbc.M500526200 |
0.797 |
|
| 2005 |
Moreira PI, Santos MS, Sena C, Seiça R, Oliveira CR. Insulin protects against amyloid beta-peptide toxicity in brain mitochondria of diabetic rats. Neurobiology of Disease. 18: 628-37. PMID 15755688 DOI: 10.1016/j.nbd.2004.10.017 |
0.405 |
|
| 2005 |
Moreira PI, Smith MA, Zhu X, Honda K, Lee HG, Aliev G, Perry G. Oxidative damage and Alzheimer's disease: are antioxidant therapies useful? Drug News & Perspectives. 18: 13-9. PMID 15753972 DOI: 10.1358/Dnp.2005.18.1.877164 |
0.824 |
|
| 2005 |
Liu Q, Smith MA, Avilá J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, et al. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radical Biology & Medicine. 38: 746-54. PMID 15721985 DOI: 10.1016/J.Freeradbiomed.2004.11.005 |
0.814 |
|
| 2005 |
Moreira PI, Custódio JB, Oliveira CR, Santos MS. Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen. Neuropharmacology. 48: 435-47. PMID 15721176 DOI: 10.1016/j.neuropharm.2004.10.012 |
0.458 |
|
| 2005 |
Smith MA, Nunomura A, Lee HG, Zhu X, Moreira PI, Avila J, Perry G. Chronological primacy of oxidative stress in Alzheimer disease. Neurobiology of Aging. 26: 579-80. PMID 15708430 DOI: 10.1016/j.neurobiolaging.2004.09.021 |
0.772 |
|
| 2005 |
Webber KM, Smith MA, Lee HG, Harris PL, Moreira P, Perry G, Zhu X. Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease. Journal of Neuroscience Research. 79: 554-60. PMID 15635602 DOI: 10.1002/jnr.20380 |
0.651 |
|
| 2005 |
Moreira PI, Siedlak SL, Aliev G, Zhu X, Cash AD, Smith MA, Perry G. Oxidative stress mechanisms and potential therapeutics in Alzheimer disease. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 921-32. PMID 15583960 DOI: 10.1007/S00702-004-0242-8 |
0.825 |
|
| 2005 |
Baykal A, arigul FS, Suleymanla G, Moreira PI, Perry G, Smith MA, Aliciguzel Y. Ciprofloxacin Does Not Exert Nephrotoxicity in Rats American Journal of Infectious Diseases. 1: 145-148. DOI: 10.3844/Ajidsp.2005.145.148 |
0.541 |
|
| 2005 |
Honda K, Moreira PI, Liu Q, Siedlak SL, Zhu X, Smith MA, Perry G. Redox active iron at the center of oxidative stress in Alzheimer disease Letters in Drug Design and Discovery. 2: 479-482. DOI: 10.2174/1570180054771545 |
0.791 |
|
| 2005 |
Moreira P, Honda K, Liu Q, Aliev G, Oliveira C, Santos M, Zhu X, Smith M, Perry G. Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved Current Medicinal Chemistry-Central Nervous System Agents. 5: 51-62. DOI: 10.2174/1568015053202714 |
0.823 |
|
| 2004 |
Moreira PI, Smith MA, Zhu X, Santos MS, Oliveira CR, Perry G. Therapeutic potential of oxidant mechanisms in Alzheimer's disease. Expert Review of Neurotherapeutics. 4: 995-1004. PMID 15853526 DOI: 10.1586/14737175.4.6.995 |
0.735 |
|
| 2004 |
Liu Q, Xie F, Siedlak SL, Nunomura A, Honda K, Moreira PI, Zhua X, Smith MA, Perry G. Neurofilament proteins in neurodegenerative diseases. Cellular and Molecular Life Sciences : Cmls. 61: 3057-75. PMID 15583867 DOI: 10.1007/S00018-004-4268-8 |
0.823 |
|
| 2004 |
Lee HG, Moreira PI, Zhu X, Smith MA, Perry G. Staying connected: synapses in Alzheimer disease. The American Journal of Pathology. 165: 1461-4. PMID 15509517 DOI: 10.1016/S0002-9440(10)63404-9 |
0.613 |
|
| 2004 |
Moreira PI, Liu Q, Honda K, Smith MA, Santos MS, Oliveira CR. Is intraneuronal amyloid beta-peptide accumulation the trigger of Alzheimer's disease pathophysiology? Journal of Alzheimer's Disease : Jad. 6: 433-4; discussion 44. PMID 15495345 DOI: 10.3233/Jad-2004-6411 |
0.789 |
|
| 2004 |
Moreira PI, Custódio JB, Oliveira CR, Santos MS. Hydroxytamoxifen protects against oxidative stress in brain mitochondria. Biochemical Pharmacology. 68: 195-204. PMID 15183131 DOI: 10.1016/j.bcp.2004.03.019 |
0.443 |
|
| 2004 |
Moreira PI, Santos MS, Moreno AM, Proença T, Seiça R, Oliveira CR. Effect of streptozotocin-induced diabetes on rat brain mitochondria. Journal of Neuroendocrinology. 16: 32-8. PMID 14962073 DOI: 10.1111/j.1365-2826.2004.01107.x |
0.403 |
|
| 2003 |
Pereira C, Agostinho P, Moreira PI, Duarte AI, Santos MS, Oliveira CR. [Neuroprotection strategies: effect of vinpocetine in vitro oxidative stress models]. Acta Mã©Dica Portuguesa. 16: 401-6. PMID 15631851 DOI: 10.20344/Amp.1220 |
0.485 |
|
| 2003 |
Moreira PI, Santos MS, Moreno AM, Seiça R, Oliveira CR. Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure. Diabetes. 52: 1449-56. PMID 12765956 DOI: 10.2337/diabetes.52.6.1449 |
0.361 |
|
| 2002 |
Moreira PI, Santos MS, Moreno A, Rego AC, Oliveira C. Effect of amyloid beta-peptide on permeability transition pore: a comparative study. Journal of Neuroscience Research. 69: 257-67. PMID 12111807 DOI: 10.1002/jnr.10282 |
0.31 |
|
| 2001 |
Moreira PI, Santos MS, Moreno A, Oliveira C. Amyloid beta-peptide promotes permeability transition pore in brain mitochondria. Bioscience Reports. 21: 789-800. PMID 12166828 DOI: 10.1023/A:1015536808304 |
0.347 |
|
| 2000 |
Moreira P, Pereira C, Santos MS, Oliveira C. Effect of zinc ions on the cytotoxicity induced by the amyloid beta-peptide. Antioxidants & Redox Signaling. 2: 317-325. PMID 11229535 DOI: 10.1089/Ars.2000.2.2-317 |
0.386 |
|
| 2000 |
Santos MS, Duarte AI, Moreira PI, Oliveira CR. Synaptosomal response to oxidative stress: effect of vinpocetine. Free Radical Research. 32: 57-66. PMID 10625217 DOI: 10.1080/10715760000300061 |
0.376 |
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