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Timothy A. Whitehead, Ph.D. - Publications

Affiliations: 
2008 University of California, Berkeley, Berkeley, CA, United States 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Whitehead TA, Banta S, Bentley WE, Betenbaugh MJ, Chan C, Clark DS, Hoesli CA, Jewett MC, Junker B, Koffas M, Kshirsagar R, Lewis A, Li CT, Maranas C, Terry Papoutsakis E, et al. The Importance and Future of Biochemical Engineering. Biotechnology and Bioengineering. PMID 32343367 DOI: 10.1002/Bit.27364  0.466
2019 Faber MS, Van Leuven J, Ederer M, Sapozhnikov Y, Wilson ZL, Wichman HA, Whitehead TA, Miller CR. Saturation mutagenesis genome engineering of infective ΦX174 bacteriophage via unamplified oligo pools and golden gate assembly. Acs Synthetic Biology. PMID 31825605 DOI: 10.1021/Acssynbio.9B00411  0.318
2019 Faber MS, Wrenbeck EE, Azouz LR, Steiner PJ, Whitehead TA. Impact of in vivo protein folding probability on local fitness landscapes. Molecular Biology and Evolution. PMID 31400199 DOI: 10.1093/Molbev/Msz184  0.308
2019 Faber MS, Whitehead TA. Data-driven engineering of protein therapeutics. Current Opinion in Biotechnology. 60: 104-110. PMID 30822697 DOI: 10.1016/J.Copbio.2019.01.015  0.379
2019 Wrenbeck EE, Bedewitz MA, Klesmith JR, Noshin S, Barry CS, Whitehead TA. An Automated Data-Driven Pipeline for Improving Heterologous Enzyme Expression. Acs Synthetic Biology. PMID 30721031 DOI: 10.1021/Acssynbio.8B00486  0.356
2018 Medina-Cucurella AV, Zhu Y, Bowen SJ, Bergeron LM, Whitehead TA. Pro region engineering of nerve growth factor by deep mutational scanning enables a yeast platform for conformational epitope mapping of anti-NGF monoclonal antibodies. Biotechnology and Bioengineering. PMID 29663315 DOI: 10.1002/Bit.26706  0.736
2018 Medina-Cucurella AV, Zhu Y, Bowen SJ, Bergeron LM, Whitehead TA. Pro region engineering of nerve growth factor by deep mutational scanning enables a yeast platform for conformational epitope mapping of anti-NGF monoclonal antibodies. Biotechnology and Bioengineering. PMID 29644656 DOI: 10.1002/bit.26606  0.729
2018 Medina-Cucurella AV, Whitehead TA. Characterizing Protein-Protein Interactions Using Deep Sequencing Coupled to Yeast Surface Display. Methods in Molecular Biology (Clifton, N.J.). 1764: 101-121. PMID 29605911 DOI: 10.1007/978-1-4939-7759-8_7  0.398
2017 Wrenbeck EE, Azouz LR, Whitehead TA. Single-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encoded. Nature Communications. 8: 15695. PMID 28585537 DOI: 10.1038/Ncomms15695  0.31
2017 Klesmith JR, Bacik JP, Wrenbeck EE, Michalczyk R, Whitehead TA. Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning. Proceedings of the National Academy of Sciences of the United States of America. PMID 28196882 DOI: 10.1073/Pnas.1614437114  0.365
2017 Whitehead TA, Bandi CK, Berger M, Park J, Chundawat SPS. Negatively Supercharging Cellulases Render Them Lignin-Resistant Acs Sustainable Chemistry & Engineering. 5: 6247-6252. DOI: 10.1021/Acssuschemeng.7B01202  0.332
2016 Wrenbeck EE, Faber MS, Whitehead TA. Deep sequencing methods for protein engineering and design. Current Opinion in Structural Biology. 45: 36-44. PMID 27886568 DOI: 10.1016/J.Sbi.2016.11.001  0.393
2016 Haarmeyer CN, Smith MD, Chundawat S, Sammond D, Whitehead TA. Insights into cellulase-lignin non-specific binding revealed by computational redesign of the surface of green fluorescent protein. Biotechnology and Bioengineering. PMID 27748522 DOI: 10.1002/Bit.26201  0.385
2015 Klesmith JR, Bacik JP, Michalczyk R, Whitehead TA. Comprehensive Sequence-Flux Mapping of a Levoglucosan Utilization Pathway in E. coli. Acs Synthetic Biology. 4: 1235-43. PMID 26369947 DOI: 10.1021/Acssynbio.5B00131  0.31
2015 Stapleton JA, Whitehead TA, Nanda V. Computational redesign of the lipid-facing surface of the outer membrane protein OmpA. Proceedings of the National Academy of Sciences of the United States of America. 112: 9632-7. PMID 26199411 DOI: 10.1073/Pnas.1501836112  0.316
2014 Bienick MS, Young KW, Klesmith JR, Detwiler EE, Tomek KJ, Whitehead TA. The interrelationship between promoter strength, gene expression, and growth rate. Plos One. 9: e109105. PMID 25286161 DOI: 10.1371/Journal.Pone.0109105  0.329
2011 Fleishman SJ, Whitehead TA, Strauch EM, Corn JE, Qin S, Zhou HX, Mitchell JC, Demerdash ON, Takeda-Shitaka M, Terashi G, Moal IH, Li X, Bates PA, Zacharias M, Park H, et al. Community-wide assessment of protein-interface modeling suggests improvements to design methodology. Journal of Molecular Biology. 414: 289-302. PMID 22001016 DOI: 10.1016/J.Jmb.2011.09.031  0.326
2011 Fleishman SJ, Corn JE, Strauch EM, Whitehead TA, Karanicolas J, Baker D. Hotspot-centric de novo design of protein binders. Journal of Molecular Biology. 413: 1047-62. PMID 21945116 DOI: 10.1016/J.Jmb.2011.09.001  0.334
2011 Fleishman SJ, Whitehead TA, Ekiert DC, Dreyfus C, Corn JE, Strauch EM, Wilson IA, Baker D. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science (New York, N.Y.). 332: 816-21. PMID 21566186 DOI: 10.1126/Science.1202617  0.312
2009 Whitehead TA, Bergeron LM, Clark DS. Tying up the loose ends: circular permutation decreases the proteolytic susceptibility of recombinant proteins. Protein Engineering, Design & Selection : Peds. 22: 607-13. PMID 19622546 DOI: 10.1093/Protein/Gzp034  0.76
2009 Slocik JM, Kim SN, Whitehead TA, Clark DS, Naik RR. Biotemplated metal nanowires using hyperthermophilic protein filaments. Small (Weinheim An Der Bergstrasse, Germany). 5: 2038-42. PMID 19517487 DOI: 10.1002/Smll.200900499  0.492
2009 Bruns N, Pustelny K, Bergeron LM, Whitehead TA, Clark DS. Mechanical nanosensor based on FRET within a thermosome: damage-reporting polymeric materials. Angewandte Chemie (International Ed. in English). 48: 5666-9. PMID 19402088 DOI: 10.1002/Anie.200900554  0.739
2009 Whitehead TA, Je E, Clark DS. Rational shape engineering of the filamentous protein gamma prefoldin through incremental gene truncation. Biopolymers. 91: 496-503. PMID 19189379 DOI: 10.1002/Bip.21157  0.562
2009 Bergeron LM, Gomez L, Whitehead TA, Clark DS. Self-renaturing enzymes: design of an enzyme-chaperone chimera as a new approach to enzyme stabilization. Biotechnology and Bioengineering. 102: 1316-22. PMID 19170240 DOI: 10.1002/Bit.22254  0.727
2009 Bruns N, Pustelny K, Bergeron L, Whitehead T, Clark D. Inside Cover: Mechanical Nanosensor Based on FRET within a Thermosome: Damage-Reporting Polymeric Materials (Angew. Chem. Int. Ed. 31/2009) Angewandte Chemie International Edition. 48: 5556-5556. DOI: 10.1002/Anie.200990160  0.746
2009 Bruns N, Pustelny K, Bergeron L, Whitehead T, Clark D. Innentitelbild: Mechanical Nanosensor Based on FRET within a Thermosome: Damage-Reporting Polymeric Materials (Angew. Chem. 31/2009) Angewandte Chemie. 121: 5664-5664. DOI: 10.1002/Ange.200990162  0.713
2008 Whitehead TA, Meadows AL, Clark DS. Controlling the self-assembly of a filamentous hyperthermophilic chaperone by an engineered capping protein. Small (Weinheim An Der Bergstrasse, Germany). 4: 956-60. PMID 18576281 DOI: 10.1002/Smll.200700848  0.527
2007 Whitehead TA, Boonyaratanakornkit BB, Höllrigl V, Clark DS. A filamentous molecular chaperone of the prefoldin family from the deep-sea hyperthermophile Methanocaldococcus jannaschii. Protein Science : a Publication of the Protein Society. 16: 626-34. PMID 17384227 DOI: 10.1110/Ps.062599907  0.734
2005 Boonyaratanakornkit BB, Simpson AJ, Whitehead TA, Fraser CM, El-Sayed NM, Clark DS. Transcriptional profiling of the hyperthermophilic methanarchaeon Methanococcus jannaschii in response to lethal heat and non-lethal cold shock. Environmental Microbiology. 7: 789-97. PMID 15892698 DOI: 10.1111/J.1462-2920.2005.00751.X  0.714
2005 Whitehead T, Boonyaratanakornkit BB, Clark DS. Discovery of a filamentous chaperone from a hyperthermophile: Molecular function and potential applications Aiche Annual Meeting, Conference Proceedings. 8392.  0.726
2004 Laksanalamai P, Whitehead TA, Robb FT. Minimal protein-folding systems in hyperthermophilic archaea. Nature Reviews. Microbiology. 2: 315-24. PMID 15031730 DOI: 10.1038/Nrmicro866  0.332
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