| Year |
Citation |
Score |
| 2024 |
Nicolaou KC, Verdine GL. 30 anniversary of Cell Chemical Biology: A conversation with founding editors K.C. Nicolaou and Gregory Verdine. Cell Chemical Biology. 31: 3-5. PMID 38242093 DOI: 10.1016/j.chembiol.2023.12.016 |
0.436 |
|
| 2022 |
Nicolaou KC, Pan S, Shelke Y, Rigol S, Bao R, Das D, Ye Q. A unified strategy for the total syntheses of eribulin and a macrolactam analogue of halichondrin B. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208938119. PMID 35930662 DOI: 10.1073/pnas.2208938119 |
0.833 |
|
| 2022 |
Nicolaou KC, Yu R, Lu Z, Alvarez FG. Total Synthesis of Gukulenin B via Sequential Tropolone Functionalizations. Journal of the American Chemical Society. PMID 35275627 DOI: 10.1021/jacs.2c01305 |
0.774 |
|
| 2021 |
Nicolaou KC, Pan S, Shelke Y, Ye Q, Das D, Rigol S. A Highly Convergent Total Synthesis of Norhalichondrin B. Journal of the American Chemical Society. PMID 34851106 DOI: 10.1021/jacs.1c10539 |
0.844 |
|
| 2021 |
Nicolaou KC, Rigol S, Pitsinos EN, Das D, Lu Y, Rout S, Schammel AW, Holte D, Lin B, Gu C, Sarvaiya H, Trinidad J, Barbour N, Valdiosera AM, Sandoval J, et al. Uncialamycin-based antibody-drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34155147 DOI: 10.1073/pnas.2107042118 |
0.803 |
|
| 2021 |
Nicolaou KC, Pan S, Shelke Y, Das D, Ye Q, Lu Y, Sau S, Bao R, Rigol S. A Reverse Approach to the Total Synthesis of Halichondrin B. Journal of the American Chemical Society. PMID 34105959 DOI: 10.1021/jacs.1c05270 |
0.828 |
|
| 2021 |
Nicolaou KC, Pan S, Pulukuri KK, Ye Q, Rigol S, Erande RD, Vourloumis D, Nocek BP, Munneke S, Lyssikatos J, Valdiosera A, Gu C, Lin B, Sarvaiaya H, Trinidad J, et al. Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis. The Journal of Organic Chemistry. PMID 33544599 DOI: 10.1021/acs.joc.0c02755 |
0.799 |
|
| 2021 |
Nicolaou KC, Rekula SR, Kumar SM, Podilapu AR, Matuszak RP, Jung PM, Lam LT, Phillips AC, Lyssikatos J, Munneke S, Gu C, Sarvaiya H, Sandoval J, Hammond M, Aujay M, et al. Design, Synthesis, and Biological Investigation of Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural Motifs. The Journal of Organic Chemistry. PMID 33417458 DOI: 10.1021/acs.joc.0c02643 |
0.32 |
|
| 2020 |
Nicolaou KC, Chen Q, Li R, Anami Y, Tsuchikama K. Total Synthesis of the Monomeric Unit of Lomaiviticin A. Journal of the American Chemical Society. 142: 20201-20207. PMID 33186022 DOI: 10.1021/jacs.0c10660 |
0.408 |
|
| 2020 |
Nicolaou KC, Krieger J, Murhade GM, Subramanian P, Dherange BD, Vourloumis D, Munneke S, Lin B, Gu C, Sarvaiaya H, Sandoval J, Zhang Z, Aujay M, Purcell JW, Gavrilyuk J. Streamlined Symmetrical Total Synthesis of Disorazole B and Design, Synthesis, and Biological Investigation of Disorazole Analogues. Journal of the American Chemical Society. PMID 32852944 DOI: 10.1021/Jacs.0C07094 |
0.842 |
|
| 2020 |
Nicolaou KC, Li R, Chen Q, Lu Z, Pitsinos EN, Schammel A, Lin B, Gu C, Sarvaiya H, Tchelepi R, Valdiosera A, Clubb J, Barbour N, Sisodiya V, Sandoval J, et al. Synthesis and Biological Evaluation of Shishijimicin A-Type Linker-Drugs and Antibody-Drug Conjugates. Journal of the American Chemical Society. PMID 32662641 DOI: 10.1021/Jacs.0C06554 |
0.735 |
|
| 2020 |
Nicolaou KC, Rigol S. Perspectives from nearly five decades of total synthesis of natural products and their analogues for biology and medicine. Natural Product Reports. PMID 32319494 DOI: 10.1039/D0Np00003E |
0.399 |
|
| 2020 |
Nicolaou KC, Shelke YG, Dherange BD, Kempema A, Lin B, Gu C, Sandoval J, Hammond M, Aujay M, Gavrilyuk J. Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1-Difluorocyclopropane and Other Fluorine Residues. The Journal of Organic Chemistry. PMID 32065746 DOI: 10.1021/Acs.Joc.0C00123 |
0.836 |
|
| 2020 |
Nicolaou KC, Das D, Lu Y, Rout S, Pitsinos EN, Lyssikatos J, Schammel A, Sandoval J, Hammond M, Aujay M, Gavrilyuk J. Total Synthesis and Biological Evaluation of Tiancimycins A and B, Yangpumicin A, and Related Anthraquinone-Fused Enediyne Antitumor Antibiotics. Journal of the American Chemical Society. PMID 31976660 DOI: 10.1021/Jacs.9B12522 |
0.826 |
|
| 2019 |
Zhang H, Li R, Ba S, Lu Z, Pitsinos EN, Li T, Nicolaou KC. DNA Binding and Cleavage Modes of Shishijimicin A. Journal of the American Chemical Society. PMID 31050893 DOI: 10.1021/Jacs.9B01800 |
0.697 |
|
| 2019 |
Nicolaou KC, Rigol S. The Role of Organic Synthesis in the Emergence and Development of Antibody-Drug Conjugates as Targeted Cancer Therapies. Angewandte Chemie (International Ed. in English). 58: 11206-11241. PMID 31012193 DOI: 10.1002/Anie.201903498 |
0.315 |
|
| 2019 |
Nicolaou KC, Pulukuri KK, Rigol S, Peitsinis Z, Yu R, Kishigami S, Cen N, Aujay M, Sandoval J, Zepeda N, Gavrilyuk J. Correction to "Short Total Synthesis of Δ-Prostaglandin J and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic Δ-Prostaglandin J Analogues". The Journal of Organic Chemistry. PMID 30715889 DOI: 10.1021/acs.joc.9b00159 |
0.827 |
|
| 2019 |
Nicolaou KC, Vassilikogiannakis G, Mägerlein W, Kranich R. Total Synthesis of Colombiasin A. Angewandte Chemie (International Ed. in English). 40: 2482-2486. PMID 29712275 DOI: 10.1002/1521-3773(20010702)40:13<2482::AID-ANIE2482>3.0.CO;2-A |
0.349 |
|
| 2019 |
Papageorgiou VP, Assimopoulou AN, Couladouros EA, Hepworth D, Nicolaou KC. The Chemistry and Biology of Alkannin, Shikonin, and Related Naphthazarin Natural Products. Angewandte Chemie (International Ed. in English). 38: 270-301. PMID 29711637 DOI: 10.1002/(Sici)1521-3773(19990201)38:3<270::Aid-Anie270>3.0.Co;2-0 |
0.308 |
|
| 2019 |
Nicolaou KC, Hepworth D. Concise and Efficient Total Syntheses of Alkannin and Shikonin. Angewandte Chemie (International Ed. in English). 37: 839-841. PMID 29711400 DOI: 10.1002/(Sici)1521-3773(19980403)37:6<839::Aid-Anie839>3.0.Co;2-J |
0.41 |
|
| 2019 |
Nicolaou KC, Roschangar F, Vourloumis D. Chemical Biology of Epothilones. Angewandte Chemie (International Ed. in English). 37: 2014-2045. PMID 29711063 DOI: 10.1002/(Sici)1521-3773(19980817)37:15<2014::Aid-Anie2014>3.0.Co;2-2 |
0.353 |
|
| 2019 |
Nicolaou KC, Vassilikogiannakis G, Mägerlein W, Kranich R. Total Synthesis of Colombiasin A This work was financially supported by the National Institutes of Health (USA) and The Skaggs Institute for Chemical Biology, postdoctoral fellowships from Bayer AG (to R.K. and W.M.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 2482-2486. PMID 11443672 DOI: 10.1002/1521-3773(20010702)40:13<2482::Aid-Anie2482>3.0.Co;2-A |
0.383 |
|
| 2019 |
Nicolaou KC, Gray D. Total Synthesis of Hybocarpone We thank Dr. D. H. Huang, Dr. G. Siuzdak and Dr. I. Ioannou for NMR spectroscopic, mass spectrometric and computational assistance, respectively. Financial support for this work was provided by the Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Novartis, Pfizer, CaPCURE, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 761-763. PMID 11241615 DOI: 10.1002/1521-3773(20010216)40:4<761::Aid-Anie7610>3.0.Co;2-0 |
0.508 |
|
| 2018 |
Nicolaou KC, Rigol S. Total Synthesis in Search of Potent Antibody-Drug Conjugate Payloads. From the Fundamentals to the Translational. Accounts of Chemical Research. 52: 127-139. PMID 30575399 DOI: 10.1021/Acs.Accounts.8B00537 |
0.396 |
|
| 2018 |
Nicolaou KC, Pulukuri KK, Rigol S, Peitsinis Z, Yu R, Kishigami S, Cen N, Aujay M, Sandoval J, Zepeda N, Gavrilyuk J. Short Total Synthesis of Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues. The Journal of Organic Chemistry. PMID 30557504 DOI: 10.1021/Acs.Joc.8B03057 |
0.835 |
|
| 2018 |
Nicolaou KC, Buchman M, Bellavance G, Krieger J, Subramanian P, Pulukuri KK. Syntheses of Cyclopropyl Analogues of Disorazoles A and B and Their Thiazole Counterparts. The Journal of Organic Chemistry. PMID 30277774 DOI: 10.1021/Acs.Joc.8B02137 |
0.811 |
|
| 2018 |
Nicolaou KC, Li R, Lu Z, Pitsinos EN, Alemany LB, Aujay M, Lee C, Sandoval J, Gavrilyuk J. Streamlined Total Synthesis of Shishijimicin A and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues thereof and Practical Syntheses of PhthNSSMe and Related Sulfenylating Reagents. Journal of the American Chemical Society. PMID 30216054 DOI: 10.1021/Jacs.8B06955 |
0.787 |
|
| 2018 |
Nicolaou KC, Rhoades D, Kumar SM. Total Syntheses of Thailanstatins A-C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents. Journal of the American Chemical Society. PMID 29943984 DOI: 10.1021/Jacs.8B04634 |
0.449 |
|
| 2018 |
Nicolaou KC, Li R, Lu Z, Pitsinos EN, Alemany LB. Total Synthesis and Full Structural Assignment of Namenamicin. Journal of the American Chemical Society. PMID 29932325 DOI: 10.1021/Jacs.8B04592 |
0.775 |
|
| 2018 |
Nicolaou KC, Erande RD, Yin J, Vourloumis D, Aujay M, Sandoval J, Munneke S, Gavrilyuk J. Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates. Journal of the American Chemical Society. PMID 29381062 DOI: 10.1021/Jacs.7B12692 |
0.799 |
|
| 2018 |
Nicolaou KC. The Emergence and Evolution of Organic Synthesis and Why It is Important to Sustain It as an Advancing Art and Science for Its Own Sake Israel Journal of Chemistry. 58: 104-113. DOI: 10.1002/Ijch.201700121 |
0.317 |
|
| 2017 |
Nicolaou KC, Pulukuri KK, Rigol S, Buchman M, Shah AA, Cen N, McCurry MD, Beabout K, Shamoo Y. Enantioselective Total Synthesis of Antibiotic CJ-16,264, Synthesis and Biological Evaluation of Designed Analogues, and Discovery of Highly Potent and Simpler Antibacterial Agents. Journal of the American Chemical Society. PMID 29064688 DOI: 10.1021/Jacs.7B08749 |
0.836 |
|
| 2017 |
Nicolaou KC, Bellavance G, Buchman M, Pulukuri KK. Total Syntheses of Disorazoles A₁ and B₁ and Full Structural Elucidation of Disorazole B₁. Journal of the American Chemical Society. 139: 15636-15639. PMID 29064682 DOI: 10.1021/Jacs.7B09843 |
0.835 |
|
| 2017 |
Nicolaou KC, Chen P, Zhu S, Cai Q, Erande RD, Li R, Sun H, Pulukuri KK, Rigol S, Aujay M, Sandoval J, Gavrilyuk J. Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues. Journal of the American Chemical Society. PMID 29052423 DOI: 10.1021/Jacs.7B08820 |
0.831 |
|
| 2017 |
Beabout K, McCurry MD, Mehta H, Shah AA, Pulukuri KK, Rigol S, Wang Y, Nicolaou KC, Shamoo Y. Experimental evolution of diverse strains as a method for the determination of biochemical mechanisms of action for novel pyrrolizidinone antibiotics. Acs Infectious Diseases. PMID 28942642 DOI: 10.1021/Acsinfecdis.7B00135 |
0.773 |
|
| 2017 |
Nicolaou KC, Rhoades D, Wang Y, Bai R, Hamel E, Aujay M, Sandoval J, Gavrilyuk J. 12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents. Journal of the American Chemical Society. PMID 28513142 DOI: 10.1021/Jacs.7B02655 |
0.458 |
|
| 2017 |
Nicolaou KC, Liu G, Beabout K, McCurry MD, Shamoo Y. Asymmetric Alkylation of Anthrones, Enantioselective Total Synthesis of (-)- and (+)-Viridicatumtoxins B and Analogues Thereof: Absolute Configuration and Potent Antibacterial Agents. Journal of the American Chemical Society. PMID 28256128 DOI: 10.1021/Jacs.6B12654 |
0.839 |
|
| 2017 |
Nicolaou KC, Rigol S. The Evolution and Impact of Total Synthesis on Chemistry, Biology and Medicine Israel Journal of Chemistry. 57: 179-191. DOI: 10.1002/Ijch.201600087 |
0.396 |
|
| 2016 |
Nicolaou KC, Rhoades D, Lamani M, Pattanayak MR, Kumar SM. Total Synthesis of Thailanstatin A. Journal of the American Chemical Society. PMID 27266914 DOI: 10.1021/Jacs.6B04781 |
0.449 |
|
| 2016 |
Nicolaou KC, Wang Y, Lu M, Mandal D, Pattanayak MR, Yu R, Shah AA, Chen JS, Zhang H, Crawford JJ, Pasunoori L, Poudel YB, Chowdari NS, Pan C, Nazeer A, et al. Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations. Journal of the American Chemical Society. PMID 27266267 DOI: 10.1021/Jacs.6B04339 |
0.725 |
|
| 2016 |
Nicolaou KC, Pulukuri KK, Yu R, Rigol S, Heretsch P, Grove CI, Hale CR, ElMarrouni A. Total Synthesis of Δ(12) -Prostaglandin J3 : Evolution of Synthetic Strategies to a Streamlined Process. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27187634 DOI: 10.1002/Chem.201601449 |
0.838 |
|
| 2016 |
Nicolaou KC, Pulukuri KK, Rigol S, Heretsch P, Yu R, Grove CI, Hale CR, ElMarrouni A, Fetz V, Brönstrup M, Aujay M, Sandoval J, Gavrilyuk J. Synthesis and Biological Investigation of Δ(12)-Prostaglandin J3 (Δ(12)-PGJ3) Analogues and Related Compounds. Journal of the American Chemical Society. PMID 27171618 DOI: 10.1021/Jacs.6B02075 |
0.805 |
|
| 2016 |
He Y, Agarwal PK, Kiran IN, Yu R, Cao B, Zou C, Zhou X, Xu H, Xu B, Zhu L, Lan Y, Nicolaou KC. Efficient Synthesis of Dimeric Oxazoles, Piperidines and Tetrahydroisoquinolines from N-Substituted 2-Oxazolones. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27113382 DOI: 10.1002/Chem.201601471 |
0.55 |
|
| 2016 |
Nicolaou KC, Cai Q, Sun H, Qin B, Zhu S. Total Synthesis of Trioxacarcins DC-45-A1, A, D, C, and C7″-epi-C and Full Structural Assignment of Trioxacarcin C. Journal of the American Chemical Society. PMID 26910506 DOI: 10.1021/Jacs.5B12687 |
0.651 |
|
| 2016 |
Nicolaou KC, Yin J, Mandal D, Erande RD, Klahn P, Jin M, Aujay M, Sandoval J, Gavrilyuk J, Vourloumis D. Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins. Journal of the American Chemical Society. PMID 26829208 DOI: 10.1021/Jacs.5B12557 |
0.806 |
|
| 2016 |
Nicolaou KC. Catalyst: Synthetic Organic Chemistry as a Force for Good Chem. 1: 331-334. DOI: 10.1016/J.Chempr.2016.08.006 |
0.37 |
|
| 2016 |
Nicolaou KC, Pulukuri KK, Yu R, Rigol S, Heretsch P, Grove CI, Hale CRH, ElMarrouni A. ChemInform Abstract: Total Synthesis of Δ12-Prostaglandin J3: Evolution of Synthetic Strategies to a Streamlined Process. Cheminform. 47. DOI: 10.1002/chin.201645186 |
0.817 |
|
| 2016 |
He Y, Agarwal PK, Kiran INC, Yu R, Cao B, Zou C, Zhou X, Xu H, Xu B, Zhu L, Lan Y, Nicolaou KC. Frontispiece: Efficient Synthesis of Dimeric Oxazoles, Piperidines and Tetrahydroisoquinolines from N -Substituted 2-Oxazolones Chemistry: a European Journal. 22. DOI: 10.1002/Chem.201682361 |
0.535 |
|
| 2015 |
Nicolaou KC, Vourloumis D, Totokotsopoulos S, Papakyriakou A, Karsunky H, Fernando H, Gavrilyuk J, Webb D, Stepan AF. Synthesis and Biopharmaceutical Evaluation of Imatinib Analogues Featuring Unusual Structural Motifs. Chemmedchem. PMID 26585829 DOI: 10.1002/Cmdc.201500510 |
0.363 |
|
| 2015 |
Nicolaou KC, Rhoades D, Wang Y, Totokotsopoulos S, Bai R, Hamel E. Synthesis and Biological Evaluation of Novel Epothilone B Side Chain Analogues. Chemmedchem. PMID 26447977 DOI: 10.1002/Cmdc.201500401 |
0.429 |
|
| 2015 |
Nicolaou KC, Lu M, Chen P, Shah AA. Practical Synthesis of p- and o-Amino- and Methoxyphenolic Anthraquinones. Angewandte Chemie (International Ed. in English). 54: 12687-91. PMID 26332286 DOI: 10.1002/Anie.201507007 |
0.371 |
|
| 2015 |
Nicolaou KC, Lu Z, Li R, Woods JR, Sohn TI. Total Synthesis of Shishijimicin A. Journal of the American Chemical Society. PMID 26133230 DOI: 10.1021/Jacs.5B05575 |
0.788 |
|
| 2015 |
Nicolaou KC, Shah AA, Korman H, Khan T, Shi L, Worawalai W, Theodorakis EA. Total Synthesis and Structural Revision of Antibiotic CJ-16,264. Angewandte Chemie (International Ed. in English). PMID 26096055 DOI: 10.1002/Anie.201504337 |
0.839 |
|
| 2015 |
Nicolaou KC, Nilewski C, Hale CR, Ahles CF, Chiu CA, Ebner C, ElMarrouni A, Yang L, Stiles K, Nagrath D. Synthesis and biological evaluation of dimeric furanoid macroheterocycles: discovery of new anticancer agents. Journal of the American Chemical Society. 137: 4766-70. PMID 25827338 DOI: 10.1021/Jacs.5B00141 |
0.327 |
|
| 2015 |
Nicolaou KC, Cai Q, Qin B, Petersen MT, Mikkelsen RJ, Heretsch P. Total synthesis of trioxacarcin DC-45-A2. Angewandte Chemie (International Ed. in English). 54: 3074-8. PMID 25583408 DOI: 10.1002/Anie.201410369 |
0.773 |
|
| 2015 |
Nicolaou KC, Heretsch P, ElMarrouni A, Hale CRH, Pulukuri KK, Kudva AK, Narayan V, Prabhu KS. ChemInform Abstract: Total Synthesis of Δ12-Prostaglandin J3, a Highly Potent and Selective Antileukemic Agent. Cheminform. 46: no-no. DOI: 10.1002/chin.201512283 |
0.817 |
|
| 2015 |
Nicolaou KC, Lu M, Chen P, Shah AA. Practical Synthesis ofp-ando-Amino- and Methoxyphenolic Anthraquinones Angewandte Chemie. 127: 12687-12691. DOI: 10.1002/Ange.201507007 |
0.372 |
|
| 2014 |
Nicolaou KC, Heretsch P, Nakamura T, Rudo A, Murata M, Konoki K. Synthesis and biological evaluation of QRSTUVWXYZA' domains of maitotoxin. Journal of the American Chemical Society. 136: 16444-51. PMID 25374117 DOI: 10.1021/Ja509829E |
0.65 |
|
| 2014 |
Nicolaou KC, Hale CR, Nilewski C, Ioannidou HA, ElMarrouni A, Nilewski LG, Beabout K, Wang TT, Shamoo Y. Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation. Journal of the American Chemical Society. 136: 12137-60. PMID 25317739 DOI: 10.1021/Ja506472U |
0.442 |
|
| 2014 |
Nicolaou KC, Shi L, Lu M, Pattanayak MR, Shah AA, Ioannidou HA, Lamani M. Total synthesis of myceliothermophins C, D, and E. Angewandte Chemie (International Ed. in English). 53: 10970-4. PMID 25163463 DOI: 10.1002/Anie.201406815 |
0.478 |
|
| 2014 |
Nicolaou KC, Heretsch P, ElMarrouni A, Hale CR, Pulukuri KK, Kudva AK, Narayan V, Prabhu KS. Total synthesis of Δ¹²-prostaglandin J₃, a highly potent and selective antileukemic agent. Angewandte Chemie (International Ed. in English). 53: 10443-7. PMID 25098181 DOI: 10.1002/Anie.201404917 |
0.846 |
|
| 2014 |
Cheng C, Liu Y, Balasis ME, Garner TP, Li J, Simmons NL, Berndt N, Song H, Pan L, Qin Y, Nicolaou KC, Gavathiotis E, Sebti SM, Li R. Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim. Marine Drugs. 12: 4311-25. PMID 25076060 DOI: 10.3390/Md12084311 |
0.5 |
|
| 2014 |
Nicolaou KC. Organic synthesis: the art and science of replicating the molecules of living nature and creating others like them in the laboratory. Proceedings. Mathematical, Physical, and Engineering Sciences / the Royal Society. 470: 20130690. PMID 24611027 DOI: 10.1098/Rspa.2013.0690 |
0.365 |
|
| 2014 |
Cheng C, Liu Y, Balasis ME, Simmons NL, Li J, Song H, Pan L, Qin Y, Nicolaou KC, Sebti SM, Li R. Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim. Marine Drugs. 12: 1335-48. PMID 24608970 DOI: 10.3390/Md12031335 |
0.505 |
|
| 2014 |
Nicolaou KC, Hale CRH. The endeavor of total synthesis and its impact on chemistry, biology and medicine National Science Review. 1: 233-252. DOI: 10.1093/Nsr/Nwu001 |
0.458 |
|
| 2013 |
Bunnage ME, Nicolaou KC. The oxide anion accelerated retro-diels-alder reaction. Chemistry (Weinheim An Der Bergstrasse, Germany). 3: 187-92. PMID 24022946 DOI: 10.1002/Chem.19970030204 |
0.32 |
|
| 2013 |
Mishra OP, Simmons N, Tyagi S, Pietrofesa R, Shuvaev VV, Valiulin RA, Heretsch P, Nicolaou KC, Christofidou-Solomidou M. Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs). Bioorganic & Medicinal Chemistry Letters. 23: 5325-8. PMID 23978651 DOI: 10.1016/J.Bmcl.2013.07.062 |
0.623 |
|
| 2013 |
Nicolaou KC, Nilewski C, Hale CR, Ioannidou HA, ElMarrouni A, Koch LG. Total synthesis and structural revision of viridicatumtoxin B. Angewandte Chemie (International Ed. in English). 52: 8736-41. PMID 23893651 DOI: 10.1002/Anie.201304691 |
0.417 |
|
| 2013 |
Nicolaou KC, Valiulin RA. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Organic & Biomolecular Chemistry. 11: 4154-63. PMID 23685867 DOI: 10.1039/C3Ob40654G |
0.325 |
|
| 2013 |
Nicolaou KC, Yu R, Shi L, Cai Q, Lu M, Heretsch P. General synthetic approach to functionalized dihydrooxepines. Organic Letters. 15: 1994-7. PMID 23550898 DOI: 10.1021/Ol4006689 |
0.769 |
|
| 2013 |
Nicolaou KC. The emergence of the structure of the molecule and the art of its synthesis. Angewandte Chemie (International Ed. in English). 52: 131-46. PMID 23203813 DOI: 10.1002/Anie.201207081 |
0.408 |
|
| 2013 |
Nicolaou KC, Yu R, Shi L, Cai Q, Lu M, Heretsch P. ChemInform Abstract: General Synthetic Approach to Functionalized Dihydrooxepines. Cheminform. 44: no-no. DOI: 10.1002/chin.201334176 |
0.62 |
|
| 2013 |
Nicolaou KC, Nilewski C, Hale CRH, Ioannidou HA, ElMarrouni A, Koch LG. Cover Picture: Total Synthesis and Structural Revision of Viridicatumtoxin B (Angew. Chem. Int. Ed. 33/2013) Angewandte Chemie. 52: 8475-8475. DOI: 10.1002/Anie.201305680 |
0.424 |
|
| 2013 |
Anderson HL, Lloyd-Jones GC, O'Brien P, Schofield CJ, Stephan DW, Nicolaou KC, Férey G, Meerholz K. New Fellows of the Royal Society: H. L. Anderson, G. C. Lloyd-Jones, P. O'Brien, C. J. Schofield, D. W. Stephan, K. C. Nicolaou / Lavoisier Medal: G. Férey / Richard Willstätter Lectureship: K. Meerholz Angewandte Chemie - International Edition. 52: 7071-7072. DOI: 10.1002/anie.201304013 |
0.31 |
|
| 2012 |
Nicolaou KC, Lu M, Totokotsopoulos S, Heretsch P, Giguère D, Sun YP, Sarlah D, Nguyen TH, Wolf IC, Smee DF, Day CW, Bopp S, Winzeler EA. Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents. Journal of the American Chemical Society. 134: 17320-32. PMID 22978674 DOI: 10.1021/Ja308429F |
0.799 |
|
| 2012 |
Nicolaou KC, Hale CR, Nilewski C, Ioannidou HA. Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance. Chemical Society Reviews. 41: 5185-238. PMID 22743704 DOI: 10.1039/C2Cs35116A |
0.413 |
|
| 2012 |
Nicolaou KC, Hale CR, Nilewski C. A total synthesis trilogy: calicheamicin γ1(I), Taxol®, and brevetoxin A. Chemical Record (New York, N.Y.). 12: 407-41. PMID 22711588 DOI: 10.1002/Tcr.201200005 |
0.371 |
|
| 2012 |
Nicolaou KC, Valiulin RA, Pokorski JK, Chang V, Chen JS. Bio-inspired synthesis and biological evaluation of a colchicine-related compound library. Bioorganic & Medicinal Chemistry Letters. 22: 3776-80. PMID 22542017 DOI: 10.1016/J.Bmcl.2012.04.007 |
0.354 |
|
| 2012 |
Bian M, Wang Z, Xiong X, Sun Y, Matera C, Nicolaou KC, Li A. Total syntheses of anominine and tubingensin A. Journal of the American Chemical Society. 134: 8078-81. PMID 22537293 DOI: 10.1021/Ja302765M |
0.569 |
|
| 2012 |
Nicolaou KC, Hale CR, Ebner C, Nilewski C, Ahles CF, Rhoades D. Synthesis of macroheterocycles through intramolecular oxidative coupling of furanoid β-ketoesters. Angewandte Chemie (International Ed. in English). 51: 4726-30. PMID 22489095 DOI: 10.1002/Anie.201201538 |
0.423 |
|
| 2011 |
Nicolaou KC, Sun YP, Sarlah D, Zhan W, Wu TR. Bioinspired synthesis of hirsutellones A, B, and C. Organic Letters. 13: 5708-10. PMID 21913732 DOI: 10.1021/Ol202239U |
0.663 |
|
| 2011 |
Nicolaou KC, Ellery SP, Rivas F, Saye K, Rogers E, Workinger TJ, Schallenberger M, Tawatao R, Montero A, Hessell A, Romesberg F, Carson D, Burton D. Synthesis and biological evaluation of 2',4'- and 3',4'-bridged nucleoside analogues. Bioorganic & Medicinal Chemistry. 19: 5648-69. PMID 21840722 DOI: 10.1016/J.Bmc.2011.07.022 |
0.8 |
|
| 2011 |
Nicolaou KC, Kiappes JL, Tian W, Gondi VB, Becker J. Synthesis of the carboline disaccharide domain of shishijimicin A. Organic Letters. 13: 3924-7. PMID 21711032 DOI: 10.1021/Ol201444T |
0.817 |
|
| 2011 |
Nicolaou KC, Aversa RJ. Maitotoxin: An Inspiration for Synthesis. Israel Journal of Chemistry. 51: 359-377. PMID 21709816 DOI: 10.1002/Ijch.201100003 |
0.685 |
|
| 2011 |
Nicolaou KC, Totokotsopoulos S, Giguère D, Sun YP, Sarlah D. Total synthesis of epicoccin G. Journal of the American Chemical Society. 133: 8150-3. PMID 21548595 DOI: 10.1021/Ja2032635 |
0.664 |
|
| 2011 |
Nicolaou KC, Simmons NL, Ying Y, Heretsch PM, Chen JS. Enantioselective dichlorination of allylic alcohols. Journal of the American Chemical Society. 133: 8134-7. PMID 21542622 DOI: 10.1021/Ja202555M |
0.654 |
|
| 2011 |
Nicolaou KC, Adsool VA, Hale CR. An expedient synthesis of a functionalized core structure of bielschowskysin. Angewandte Chemie (International Ed. in English). 50: 5149-52. PMID 21523870 DOI: 10.1002/Anie.201101360 |
0.452 |
|
| 2011 |
Nicolaou KC, Simmons NL, Chen JS, Haste NM, Nizet V. Total synthesis and biological evaluation of marinopyrrole A and analogues. Tetrahedron Letters. 52: 2041-2043. PMID 21499535 DOI: 10.1016/J.Tetlet.2010.09.059 |
0.429 |
|
| 2011 |
Wenzel M, Patra M, Albrecht D, Chen DY, Nicolaou KC, Metzler-Nolte N, Bandow JE. Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies. Antimicrobial Agents and Chemotherapy. 55: 2590-6. PMID 21383089 DOI: 10.1128/Aac.00078-11 |
0.305 |
|
| 2011 |
Nicolaou KC, Jiang X, Lindsay-Scott PJ, Corbu A, Yamashiro S, Bacconi A, Fowler VM. Total synthesis and biological evaluation of monorhizopodin and 16-epi-monorhizopodin. Angewandte Chemie (International Ed. in English). 50: 1139-44. PMID 21268213 DOI: 10.1002/Anie.201006780 |
0.566 |
|
| 2011 |
Nicolaou KC, Sanchini S, Sarlah D, Lu G, Wu TR, Nomura DK, Cravatt BF, Cubitt B, de la Torre JC, Hessell AJ, Burton DR. Design, synthesis, and biological evaluation of a biyouyanagin compound library. Proceedings of the National Academy of Sciences of the United States of America. 108: 6715-20. PMID 21245351 DOI: 10.1073/Pnas.1015258108 |
0.669 |
|
| 2011 |
Nicolaou KC, Baker TM, Nakamura T. Synthesis of the WXYZA' domain of maitotoxin. Journal of the American Chemical Society. 133: 220-6. PMID 21166430 DOI: 10.1021/Ja109533Y |
0.444 |
|
| 2011 |
Nicolaou KC, Seo JH, Nakamura T, Aversa RJ. Synthesis of the C'D'E'F' domain of maitotoxin. Journal of the American Chemical Society. 133: 214-9. PMID 21166429 DOI: 10.1021/Ja109531D |
0.638 |
|
| 2011 |
Nicolaou KC, Aversa RJ. Cover Picture: Maitotoxin: An Inspiration for Synthesis (Isr. J. Chem. 3-4/2011) Israel Journal of Chemistry. 51: 305-305. DOI: 10.1002/Ijch.201190005 |
0.68 |
|
| 2011 |
Nicolaou KC, Simmons NL, Ying Y, Heretsch PM, Chen JS. ChemInform Abstract: Enantioselective Dichlorination of Allylic Alcohols. Cheminform. 42: no-no. DOI: 10.1002/chin.201143065 |
0.595 |
|
| 2011 |
Nicolaou KC, Seo JH, Nakamura T, Aversa RJ. ChemInform Abstract: Synthesis of the C′D′E′F′ Domain of Maitotoxin. Cheminform. 42: no-no. DOI: 10.1002/chin.201114213 |
0.59 |
|
| 2010 |
Nicolaou KC, Wang J, Tang Y, Botta L. Total synthesis of sporolide B and 9-epi-sporolide B. Journal of the American Chemical Society. 132: 11350-63. PMID 20698702 DOI: 10.1021/Ja1048994 |
0.526 |
|
| 2010 |
Nicolaou KC, Gelin CF, Seo JH, Huang Z, Umezawa T. Synthesis of the QRSTU domain of maitotoxin and its 85-epi- and 86-epi-diastereoisomers. Journal of the American Chemical Society. 132: 9900-7. PMID 20666400 DOI: 10.1021/Ja103708J |
0.419 |
|
| 2010 |
Nicolaou KC, Sun YP, Korman H, Sarlah D. Asymmetric total synthesis of cylindrocyclophanes A and F through cyclodimerization and a Ramberg-Bäcklund reaction. Angewandte Chemie (International Ed. in English). 49: 5875-8. PMID 20623817 DOI: 10.1002/Anie.201003500 |
0.805 |
|
| 2010 |
Nicolaou KC, Sanchini S, Wu TR, Sarlah D. Total synthesis and structural revision of biyouyanagin B. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 7678-82. PMID 20572192 DOI: 10.1002/Chem.201001474 |
0.673 |
|
| 2010 |
Nicolaou KC, Kang Q, Ng SY, Chen DY. Total synthesis of englerin A. Journal of the American Chemical Society. 132: 8219-22. PMID 20496885 DOI: 10.1021/Ja102927N |
0.387 |
|
| 2010 |
Nicolaou KC, Kang Q, Wu TR, Lim CS, Chen DY. Total synthesis and biological evaluation of the resveratrol-derived polyphenol natural products hopeanol and hopeahainol A. Journal of the American Chemical Society. 132: 7540-8. PMID 20462209 DOI: 10.1021/Ja102623J |
0.485 |
|
| 2010 |
Nicolaou KC, Ortiz A, Zhang H, Dagneau P, Lanver A, Jennings MP, Arseniyadis S, Faraoni R, Lizos DE. Total synthesis and structural revision of vannusals A and B: synthesis of the originally assigned structure of vannusal B. Journal of the American Chemical Society. 132: 7138-52. PMID 20443561 DOI: 10.1021/Ja100740T |
0.825 |
|
| 2010 |
Nicolaou KC, Ortiz A, Zhang H, Guella G. Total synthesis and structural revision of vannusals A and B: synthesis of the true structures of vannusals A and B. Journal of the American Chemical Society. 132: 7153-76. PMID 20443558 DOI: 10.1021/Ja100742B |
0.451 |
|
| 2010 |
Nicolaou KC, Aversa RJ, Jin J, Rivas F. Synthesis of the ABCDEFG ring system of maitotoxin. Journal of the American Chemical Society. 132: 6855-61. PMID 20415445 DOI: 10.1021/Ja102260Q |
0.847 |
|
| 2010 |
Nicolaou KC, Ding H, Richard JA, Chen DY. Total synthesis of echinopines A and B. Journal of the American Chemical Society. 132: 3815-8. PMID 20184316 DOI: 10.1021/Ja9093988 |
0.467 |
|
| 2010 |
Hayden AE, Paton RS, Becker J, Lim YH, Nicolaou KC, Houk KN. Origins of regioselectivity of Diels-Alder reactions for the synthesis of bisanthraquinone antibiotic BE-43472B. The Journal of Organic Chemistry. 75: 922-8. PMID 20027998 DOI: 10.1021/Jo902572Y |
0.779 |
|
| 2010 |
Nicolaou KC, Dong L, Deng L, Talbot AC, Chen DY. Synthesis of functionalized maoecrystal V core structures. Chemical Communications (Cambridge, England). 46: 70-2. PMID 20024296 DOI: 10.1039/B917045F |
0.392 |
|
| 2010 |
Nicolaou K, Sun Y, Korman H, Sarlah D. Synthesis of Cylindrocyclophane F Synfacts. 2010: 1098-1098. DOI: 10.1055/S-0030-1258620 |
0.779 |
|
| 2010 |
Nicolaou KC, Sarlah D, Wu TR, Zhan W. Synthesis of Hirsutellone B Synfacts. 2010: 139-139. DOI: 10.1055/S-0029-1219028 |
0.673 |
|
| 2010 |
Nicolaou KC, Dalby SM, Li S, Suzuki T, Chen DY-. Synthesis of (+)-Haplophytine Synfacts. 2010: 1-1. DOI: 10.1055/S-0029-1218392 |
0.489 |
|
| 2010 |
Nicolaou KC, Sanchini S, Wu TR, Sarlah D. ChemInform Abstract: Total Synthesis and Structural Revision of Biyouyanagin B. Cheminform. 41: no-no. DOI: 10.1002/chin.201050182 |
0.653 |
|
| 2010 |
Nicolaou KC, Ortiz A, Zhang H, Dagneau P, Lanver A, Jennings MP, Arseniyadis S, Faraoni R, Lizos DE. ChemInform Abstract: Total Synthesis and Structural Revision of Vannusals A and B: Synthesis of the Originally Assigned Structure of Vannusal B. Cheminform. 41: no-no. DOI: 10.1002/chin.201037181 |
0.823 |
|
| 2010 |
Nicolaou KC, Chen JS. ChemInform Abstract: The Art of Total Synthesis Through Cascade Reactions Cheminform. 41. DOI: 10.1002/chin.201007221 |
0.303 |
|
| 2010 |
Nicolaou KC, Li A, Ellery SP, Edmonds DJ. ChemInform Abstract: Rhodium-Catalyzed Asymmetric Enyne Cycloisomerization of Terminal Alkynes and Formal Total Synthesis of (-)-Platensimycin. Cheminform. 41: no-no. DOI: 10.1002/chin.201001031 |
0.353 |
|
| 2010 |
Nicolaou KC, Ritzen A, Namoto K, Buey RM, Diaz JF, Andreu JM, Wartmann M, Altmann K, O'Brate A, Giannakakou P. ChemInform Abstract: Chemical Synthesis and Biological Evaluation of Novel Epothilone B and trans-12,13-Cyclopropyl Epothilone B Analogues. Cheminform. 33: no-no. DOI: 10.1002/chin.200250201 |
0.745 |
|
| 2010 |
Nicolaou KC, Snyder SA, Montagnon T, Vassilikogiannakis G. ChemInform Abstract: The Diels-Alder Reaction in Total Synthesis Cheminform. 33: no-no. DOI: 10.1002/chin.200236259 |
0.665 |
|
| 2010 |
Nicolaou KC, Montagnon T, Baran PS. ChemInform Abstract: HIO3 and I2O5: Mild and Selective Alternative Reagents to IBX for the Dehydrogenation of Aldehydes and Ketones. Cheminform. 33: no-no. DOI: 10.1002/chin.200233057 |
0.601 |
|
| 2010 |
Nicolaou KC, Zhong Y, Baran PS, Jung J, Choi H, Yoon WH. ChemInform Abstract: Total Synthesis of the CP-Molecules (CP-263,114 and CP-225,917, Phomoidrides B and A). Part 3. Completion and Synthesis of Advanced Analogues. Cheminform. 33: no-no. DOI: 10.1002/chin.200232232 |
0.758 |
|
| 2010 |
Nicolaou KC, Jung J, Yoon WH, Fong KC, Choi H, He Y, Zhong Y, Baran PS. ChemInform Abstract: Total Synthesis of the CP-Molecules (CP-263,114 and CP-225,917, Phomoidrides B and A). Part 1. Racemic and Asymmetric Synthesis of Bicyclo[4.3.1] Key Building Blocks. Cheminform. 33: no-no. DOI: 10.1002/chin.200232231 |
0.757 |
|
| 2010 |
Nicolaou KC, Baran PS, Zhong Y, Sugita K. ChemInform Abstract: Iodine(V) Reagents in Organic Synthesis. Part 1. Synthesis of Polycyclic Heterocycles via Dess-Martin Periodinane Mediated Cascade Cyclization: Generality, Scope, and Mechanism of the Reaction. Cheminform. 33: no-no. DOI: 10.1002/chin.200231172 |
0.659 |
|
| 2010 |
Nicolaou KC, Huang X, Snyder SA, Rao PB, Bella M, Reddy MV. ChemInform Abstract: A Novel Regio- and Stereoselective Synthesis of Sulfamidates from 1,2-Diols Using Burgess and Related Reagents: A Facile Entry into β-Amino Alcohols. Cheminform. 33: no-no. DOI: 10.1002/chin.200231088 |
0.61 |
|
| 2010 |
Nicolaou KC, Gray DLF, Montagnon T, Harrison ST. ChemInform Abstract: Oxidation of Silyl Enol Ethers by Using IBX and IBX×N-Oxide Complexes: A Mild and Selective Reaction for the Synthesis of Enones. Cheminform. 33: no-no. DOI: 10.1002/chin.200231052 |
0.592 |
|
| 2010 |
Nicolaou KC, Montagnon T, Baran PS. ChemInform Abstract: Modulation of the Reactivity Profile of IBX by Ligand Complexation: Ambient Temperature Dehydrogenation of Aldehydes and Ketones to α,β-Unsaturated Carbonyl Compounds. Cheminform. 33: no-no. DOI: 10.1002/chin.200231051 |
0.557 |
|
| 2010 |
Nicolaou KC, Montagnon T, Baran PS, Zhong Y. ChemInform Abstract: Iodine(V) Reagents in Organic Synthesis. Part 4. o-Iodoxybenzoic Acid as a Chemospecific Tool for Single Electron Transfer-Based Oxidation Processes. Cheminform. 33: no-no. DOI: 10.1002/chin.200231050 |
0.57 |
|
| 2010 |
Nicolaou KC, Sugita K, Baran PS, Zhong Y. ChemInform Abstract: Iodine(V) Reagents in Organic Synthesis. Part 2. Access to Complex Molecular Architectures via Dess-Martin Periodinane Generated o-Imidoquinones. Cheminform. 33: no-no. DOI: 10.1002/chin.200231049 |
0.591 |
|
| 2010 |
Nicolaou KC, Baran PS, Zhong Y, Barluenga S, Hunt KW, Kranich R, Vega JA. ChemInform Abstract: Iodine(V) Reagents in Organic Synthesis. Part 3. New Routes to Heterocyclic Compounds via o-Iodoxybenzoic Acid-Mediated Cyclizations: Generality, Scope, and Mechanism. Cheminform. 33: no-no. DOI: 10.1002/chin.200231035 |
0.748 |
|
| 2010 |
Nicolaou KC, Baran PS, Zhong Y, Fong KC, Choi H. ChemInform Abstract: Total Synthesis of the CP-Molecules (CP-263,114 and CP-225,917, Phomoidrides B and A). Part 2. Model Studies for the Construction of Key Structural Elements and First-Generation Strategy. Cheminform. 33: no-no. DOI: 10.1002/chin.200230261 |
0.635 |
|
| 2010 |
Nicolaou KC, Vassilikogiannakis G, Maegerlein W, Kranich R. ChemInform Abstract: Total Synthesis of Colombiasin A (I) and Determination of Its Absolute Configuration. Cheminform. 33: no-no. DOI: 10.1002/chin.200221138 |
0.327 |
|
| 2010 |
Nicolaou KC, Huang X, Giuseppone N, Rao PB, Bella M, Reddy MV, Snyder SA. ChemInform Abstract: Construction of the Complete Aromatic Core of Diazonamide A by a Novel Hetero Pinacol Macrocyclization Cascade Reaction. Cheminform. 33: no-no. DOI: 10.1002/chin.200218158 |
0.745 |
|
| 2010 |
Nicolaou KC, Gray D, Tae J. ChemInform Abstract: Total Synthesis of Hamigerans. Part 2. Implementation of the Intramolecular Diels-Alder Trapping of Photochemically Generated Hydroxy-o-quinodimethanes; Strategy and Completion of the Synthesis. Cheminform. 33: no-no. DOI: 10.1002/chin.200204039 |
0.314 |
|
| 2010 |
Nicolaou KC, Vassilikogiannakis G, Maegerlein W, Kranich R. ChemInform Abstract: Total Synthesis of Colombiasin A. Cheminform. 32: no-no. DOI: 10.1002/chin.200140188 |
0.361 |
|
| 2010 |
Nicolaou KC, Zhong Y, Baran PS, Sugita K. ChemInform Abstract: Rapid Access to Complex Molecular Architectures via o-Azaquinones. Cheminform. 32: no-no. DOI: 10.1002/chin.200136100 |
0.539 |
|
| 2010 |
Nicolaou KC, Mitchell HJ. ChemInform Abstract: Adventures in Carbohydrate Chemistry: New Synthetic Technologies, Chemical Synthesis, Molecular Design, and Chemical Biology Cheminform. 32: no-no. DOI: 10.1002/chin.200132256 |
0.607 |
|
| 2010 |
Nicolaou KC, Pihko PM, Diedrichs N, Zou N, Bernal F. ChemInform Abstract: Synthesis of the FGHI Ring System of Azaspiracid. Cheminform. 32: no-no. DOI: 10.1002/chin.200129197 |
0.648 |
|
| 2010 |
Nicolaou KC, Baran PS, Zhong Y. ChemInform Abstract: Selective Oxidation at Carbon Adjacent to Aromatic Systems with IBX. Cheminform. 32: no-no. DOI: 10.1002/chin.200127045 |
0.541 |
|
| 2010 |
Nicolaou KC, Gray D. ChemInform Abstract: Total Synthesis of Hybocarpone (I). Cheminform. 32: no-no. DOI: 10.1002/chin.200122168 |
0.361 |
|
| 2010 |
Nicolaou KC, Jung J, Yoon WH, He Y, Zhong Y, Baran PS. ChemInform Abstract: The Absolute Configuration and Asymmetric Total Synthesis of the CP Molecules (CP-263,114 and CP-225,917, Phomoidrides B and A). Cheminform. 31: no-no. DOI: 10.1002/chin.200030239 |
0.734 |
|
| 2010 |
Nicolaou KC, Murphy F, Barluenga S, Ohshima T, Wei H, Xu J, Gray DLF, Baudoin O. ChemInform Abstract: Total Synthesis of the Novel Immunosuppressant Sanglifehrin A (I). Cheminform. 31: no-no. DOI: 10.1002/chin.200030237 |
0.772 |
|
| 2010 |
Nicolaou KC, Vassilikogiannakis G, Simonsen KB, Baran PS, Zhong Y, Vidali V, Pitsinos EN, Couladouros EA. ChemInform Abstract: Biomimetic Total Synthesis of Bisorbicillinol, Bisorbibutenolide, Trichodimerol, and Designed Analogues of the Bisorbicillinoids. Cheminform. 31: no-no. DOI: 10.1002/chin.200028237 |
0.644 |
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| 2010 |
Nicolaou KC, Li Y, Weyershausen B, Wei H. ChemInform Abstract: Synthesis of the Macrocyclic Core of Apoptolidin. Cheminform. 31: no-no. DOI: 10.1002/chin.200022206 |
0.328 |
|
| 2010 |
Nicolaou KC, Mitchell HJ, Fylaktakidou KC, Suzuki H, Rodriguez RM. ChemInform Abstract: 1,2-Seleno Migrations in Carbohydrate Chemistry: Solution and Solid-Phase Synthesis of 2-Deoxy Glycosides, Orthoesters, and Allyl Orthoesters. Cheminform. 31: no-no. DOI: 10.1002/chin.200022188 |
0.594 |
|
| 2010 |
Nicolaou KC, Snyder SA, Bigot A, Pfefferkorn JA. ChemInform Abstract: Solution and Solid-Phase Synthesis of Functionalized 3-Arylbenzofurans by a Novel Cyclofragmentation-Release Pathway. Cheminform. 31: no-no. DOI: 10.1002/chin.200021111 |
0.603 |
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| 2010 |
Nicolaou KC, Zhong Y, Baran PS. ChemInform Abstract: New Synthetic Technology for the Rapid Construction of Novel Heterocycles. Part 2. The Reaction of IBX with Anilides and Related Compounds. Cheminform. 31: no-no. DOI: 10.1002/chin.200017046 |
0.607 |
|
| 2010 |
Nicolaou KC, Zhong Y, Baran PS. ChemInform Abstract: New Synthetic Technology for the Rapid Construction of Novel Heterocycles. Part 1. The Reaction of Dess-Martin Periodinane with Anilides and Related Compounds. Cheminform. 31: no-no. DOI: 10.1002/chin.200017045 |
0.607 |
|
| 2010 |
Nicolaou KC, Simonsen KB, Vassilikogiannakis G, Baran PS, Vidali VP, Pitsinos EN, Couladouros EA. ChemInform Abstract: Biomimetic Explorations Towards the Bisorbicillinoids: Total Synthesis of Bisorbicillinol, Bisorbibutenolide, and Trichodimerol. Cheminform. 31: no-no. DOI: 10.1002/chin.200012258 |
0.676 |
|
| 2010 |
Nicolaou KC, Pfefferkorn J, Xu J, Winssinger N, Ohshima T, Kim S, Hosokawa S, Vourloumis D, van Delft F, Li T. ChemInform Abstract: Total Synthesis and Chemical Biology of the Sarcodictyins Cheminform. 31: no-no. DOI: 10.1002/chin.200011255 |
0.605 |
|
| 2010 |
Nicolaou KC, Mitchell HJ, Rodriguez RM, Fylaktakidou KC, Suzuki H. ChemInform Abstract: Total Synthesis of Everninomicin 13,384-1. Part 3. Synthesis of the DE Fragment and Completion of the Total Synthesis. Cheminform. 31: no-no. DOI: 10.1002/chin.200011239 |
0.681 |
|
| 2010 |
Nicolaou KC, Mitchell HJ, Suzuki H, Rodriguez RM, Baudoin O, Fylaktakidou KC. ChemInform Abstract: Total Synthesis of Everninomicin 13,384-1. Part 1. Synthesis of the A1B(A)C Fragment. Cheminform. 31: no-no. DOI: 10.1002/chin.200011237 |
0.765 |
|
| 2010 |
Nicolaou KC, Xu J, Murphy F, Barluenga S, Baudoin O, Wei H, Gray DLF, Ohshima T. ChemInform Abstract: Total Synthesis of Sanglifehrin A. Cheminform. 30: no-no. DOI: 10.1002/chin.199947252 |
0.77 |
|
| 2010 |
Nicolaou KC, Baran PS, Zhong Y, Choi H, Fong KC, He Y, Yoon WH. ChemInform Abstract: New Synthetic Technology for the Synthesis of Hindered α-Diazoketones via Acyl Mesylates. Cheminform. 30: no-no. DOI: 10.1002/chin.199947102 |
0.71 |
|
| 2010 |
Nicolaou KC, He Y, Fong KC, Yoon WH, Choi H, Zhong Y, Baran PS. ChemInform Abstract: Novel Strategies to Construct the γ-Hydroxy Lactone Moiety of the CP Molecules. Synthesis of the CP-225,917 Core Skeleton. Cheminform. 30: no-no. DOI: 10.1002/chin.199938215 |
0.751 |
|
| 2010 |
Nicolaou KC, Ohshima T, Murphy F, Barluenga S, Xu J, Winssinger N. ChemInform Abstract: Synthesis of the Macrocyclic Core of Sanglifehrin A. Cheminform. 30: no-no. DOI: 10.1002/chin.199934254 |
0.741 |
|
| 2010 |
Nicolaou KC, Baran PS, Zhong Y, Fong KC, He Y, Yoon WH, Choi H. ChemInform Abstract: Total Synthesis of the CP Molecules CP-225,917 and CP-263,114. Part 2. Evolution of the Final Strategy. Cheminform. 30: no-no. DOI: 10.1002/chin.199933278 |
0.735 |
|
| 2010 |
Nicolaou KC, Baran PS, Zhong Y, Choi H, Yoon WH, He Y, Fong KC. ChemInform Abstract: Total Synthesis of the CP Molecules CP-263,114 and CP-225,917. Part 1. Synthesis of Key Intermediates and Intelligence Gathering. Cheminform. 30: no-no. DOI: 10.1002/chin.199933277 |
0.759 |
|
| 2010 |
Weinstein DS, Nicolaou KC. ChemInform Abstract: Synthesis of the Namenamicin A-C Disaccharide: Towards the Total Synthesis of Namenamicin. Cheminform. 30: no-no. DOI: 10.1002/chin.199930208 |
0.699 |
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| 2010 |
Nicolaou KC, Baran PS, Jautelat R, He Y, Fong KC, Choi H, Yoon WH, Zhong Y. ChemInform Abstract: A Novel Route to the Fused Maleic Anhydride Moiety of CP Molecules. Cheminform. 30: no-no. DOI: 10.1002/chin.199923283 |
0.711 |
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| 2010 |
Nicolaou KC, Mitchell HJ, Jain NF, Winssinger N, Hughes R, Bando T. ChemInform Abstract: Total Synthesis of Vancomycin. Cheminform. 30: no-no. DOI: 10.1002/chin.199918228 |
0.753 |
|
| 2010 |
NICOLAOU KC, JAIN NF, NATARAJAN S, HUGHES R, SOLOMON ME, LI H, RAMANJULU JM, TAKAYANAGI M, KOUMBIS AE, BANDO T. ChemInform Abstract: Total Synthesis of Vancomycin Aglycon. Part 2. Synthesis of Amino Acids 1-3 and Construction of the AB-COD-DOE Ring Skeleton. Cheminform. 30: no-no. DOI: 10.1002/chin.199910254 |
0.325 |
|
| 2010 |
NICOLAOU KC, PASTOR J, BARLUENGA S, WINSSINGER N. ChemInform Abstract: Polymer-Supported Selenium Reagents for Organic Synthesis. Cheminform. 30: no-no. DOI: 10.1002/chin.199902057 |
0.68 |
|
| 2010 |
NICOLAOU KC, RODRIGUEZ RM, MITCHELL HJ, VAN DELFT FL. ChemInform Abstract: Stereocontrolled Synthesis of the Everninomicin A1B(A)C Ring Framework. Cheminform. 29: no-no. DOI: 10.1002/chin.199849288 |
0.636 |
|
| 2010 |
NICOLAOU KC, MITCHELL HJ, VAN DELFT FL, RUEBSAM F, RODRIGUEZ RM. ChemInform Abstract: Expeditious Routes to Evernitrose and Vancosamine Derivatives and Synthesis of a Model Vancomycin Aryl Glycoside. Cheminform. 29: no-no. DOI: 10.1002/chin.199849287 |
0.649 |
|
| 2010 |
NICOLAOU KC, SHI G, NAMOTO K, BERNAL F. ChemInform Abstract: Synthesis of N-Heterocycles via Lactam-Derived Ketene Aminal Phosphates. Asymmetric Synthesis of Cyclic Amino Acids. Cheminform. 29: no-no. DOI: 10.1002/chin.199848171 |
0.759 |
|
| 2010 |
NICOLAOU KC, FINLAY MRV, NINKOVIC S, SARABIA F. ChemInform Abstract: Total Synthesis of 26-Hydroxy-epothilone B and Related Analogues via a Macrolactonization Based Strategy. Cheminform. 29: no-no. DOI: 10.1002/chin.199840268 |
0.321 |
|
| 2010 |
NICOLAOU KC, KIM S, PFEFFERKORN J, XU J, OHSHIMA T, HOSOKAWA S, VOURLOUMIS D, LI T. ChemInform Abstract: Synthesis and Biological Activity of Sarcodictyins. Cheminform. 29: no-no. DOI: 10.1002/chin.199837273 |
0.302 |
|
| 2010 |
NICOLAOU KC, NINKOVIC S, FINLAY MRV, SARABIA F, LI T. ChemInform Abstract: Total Synthesis of 26-Hydroxyepothilone B and Related Analogues. Cheminform. 29: no-no. DOI: 10.1002/chin.199819248 |
0.303 |
|
| 2010 |
NICOLAOU KC, XU J, KIM S, OHSHIMA T, HOSOKAWA S, PFEFFERKORN J. ChemInform Abstract: Synthesis of the Tricyclic Core of Eleutherobin and Sarcodictyins and Total Synthesis of Sarcodictyin A. Cheminform. 29: no-no. DOI: 10.1002/chin.199811212 |
0.37 |
|
| 2010 |
NICOLAOU KC, VAN DELFT F, OHSHIMA T, VOURLOUMIS D, XU J, HOSOKAWA S, PFEFFERKORN J, KIM S, LI T. ChemInform Abstract: Total Synthesis of Eleutherobin. Cheminform. 29: no-no. DOI: 10.1002/chin.199811211 |
0.361 |
|
| 2010 |
NICOLAOU KC, SARABIA F, FINLAY MRV, NINKOVIC S, KING NP, VOURLOUMIS D, HE Y. ChemInform Abstract: Total Synthesis of Oxazole- and Cyclopropane-Containing Epothilone B Analogues by the Macrolactonization Approach. Cheminform. 29: no-no. DOI: 10.1002/chin.199810208 |
0.313 |
|
| 2010 |
NICOLAOU KC, VALLBERG H, KING NP, ROSCHANGAR F, HE Y, VOURLOUMIS D, NICOLAOU CG. ChemInform Abstract: Total Synthesis of Oxazole- and Cyclopropane-Containing Epothilone A Analogues by the Olefin Metathesis Approach. Cheminform. 29: no-no. DOI: 10.1002/chin.199810207 |
0.35 |
|
| 2010 |
NICOLAOU KC, VAN DELFT FL, CONLEY SR, MITCHELL HJ, JIN Z, RODRIGUEZ RM. ChemInform Abstract: New Synthetic Technology for the Stereocontrolled Construction of 1,1′-Disaccharides and 1,1′:1′′,2-Trisaccharides. Synthesis of the FG Ring System of Everninomicin 13,384-1. Cheminform. 29: no-no. DOI: 10.1002/chin.199801233 |
0.629 |
|
| 2010 |
NICOLAOU KC, TRUJILLO JI, CHIBALE K. ChemInform Abstract: Design, Synthesis, and Biological Evaluation of Carbohydrate-Based Mimetics of cRGDFV. Cheminform. 28: no-no. DOI: 10.1002/chin.199743239 |
0.513 |
|
| 2010 |
NICOLAOU KC, SMITH BM, PASTOR J, WATANABE Y, WEINSTEIN DS. ChemInform Abstract: Synthesis of DNA-Binding Oligosaccharides Cheminform. 28: no-no. DOI: 10.1002/chin.199739337 |
0.615 |
|
| 2010 |
NICOLAOU KC, HAERTER MW, BOULTON L, JANDELEIT B. ChemInform Abstract: Synthesis of the Bicyclic Core or CP-225,917 and CP-263,114 by an Intramolecular Diels-Alder Reaction. Cheminform. 28: no-no. DOI: 10.1002/chin.199738290 |
0.302 |
|
| 2010 |
NICOLAOU KC, WINSSINGER N, PASTOR J, NINKOVIC S, SARABLA F, HE Y, VOURLOUMIS D, YANG Z, LI T, GIANNAKAKOU P, HAMEL E. ChemInform Abstract: Synthesis of Epothilones A and B in Solid and Solution Phase. Cheminform. 28: no-no. DOI: 10.1002/chin.199737271 |
0.517 |
|
| 2010 |
NICOLAOU KC, KOIDE K, XU J, IZRAELEWICZ MH. ChemInform Abstract: Synthetic Studies on Maduropeptin Chromophore. Part 2. Synthesis of the Madurosamine Aryl Amide and the C1′-C9′ Fragments. Cheminform. 28: no-no. DOI: 10.1002/chin.199736268 |
0.365 |
|
| 2010 |
NICOLAOU KC, KOIDE K. ChemInform Abstract: Synthetic Studies on Maduropeptin Chromophore. Part 1. Construction of the Aryl Ether and Attempted Synthesis of the (7.3.0) Bicyclic System. Cheminform. 28: no-no. DOI: 10.1002/chin.199736267 |
0.371 |
|
| 2010 |
NICOLAOU KC, UENO H. ChemInform Abstract: Oligosaccharide Synthesis from Glycosyl Fluorides and Sulfides Cheminform. 28: no-no. DOI: 10.1002/chin.199732244 |
0.344 |
|
| 2010 |
YANG Z, HE Y, VOURLOUMIS D, VALLBERG H, NICOLAOU KC. ChemInform Abstract: Total Synthesis of Epothilone A: The Olefin Metathesis Approach. Cheminform. 28: no-no. DOI: 10.1002/chin.199716266 |
0.313 |
|
| 2010 |
NICOLAOU KC, GROSS JL, KERR MA. ChemInform Abstract: Synthesis of Novel Heterocycles Related to the Dynemicin A Ring Skeleton. Cheminform. 27: no-no. DOI: 10.1002/chin.199650233 |
0.591 |
|
| 2010 |
NICOLAOU KC, AJITO K, PATRON AP, KHATUYA H, RICHTER PK, BERTINATO P. ChemInform Abstract: Total Synthesis of Swinholide A. Cheminform. 27: no-no. DOI: 10.1002/chin.199630306 |
0.361 |
|
| 2010 |
NICOLAOU KC. ChemInform Abstract: The Total Synthesis of Brevetoxin B: A Twelve-Year Odyssey in Organic Synthesis Cheminform. 27: no-no. DOI: 10.1002/chin.199627329 |
0.307 |
|
| 2010 |
NICOLAOU KC, RUTJES FPJT, THEODORAKIS EA, TIEBES J, SATO M, UNTERSTELLER E. ChemInform Abstract: Total Synthesis of Brevetoxin B. Part 3. Final Strategy and Completion. Cheminform. 27: no-no. DOI: 10.1002/chin.199608273 |
0.304 |
|
| 2010 |
NICOLAOU KC, UENO H, LIU J, NANTERMET PG, YANG Z, RENAUD J, PAULVANNAN K, CHADHA R. ChemInform Abstract: Total Synthesis of Taxol. Part 4. The Final Stages and Completion of the Synthesis Cheminform. 26: no-no. DOI: 10.1002/chin.199527229 |
0.322 |
|
| 2010 |
NICOLAOU KC, YANG Z, LIU J, NANTERMET PG, CLAIBORNE CF, RENAUD J, GUY RK, SHIBAYAMA K. ChemInform Abstract: Total Synthesis of Taxol. Part 3. Formation of Taxol′s ABC Ring Skeleton Cheminform. 26: no-no. DOI: 10.1002/chin.199527228 |
0.563 |
|
| 2010 |
NICOLAOU KC, LIU J, YANG Z, UENO H, SORENSEN EJ, CLAIBORNE CF, GUY RK, HWANG C, NAKADA M, NANTERMET PG. ChemInform Abstract: Total Synthesis of Taxol. Part 2. Construction of A and C Ring Intermediates and Initial Attempts to Construct the ABC Ring System Cheminform. 26: no-no. DOI: 10.1002/chin.199527227 |
0.529 |
|
| 2010 |
CLARK DA, DE RICCARDIS F, NICOLAOU KC. ChemInform Abstract: Studies Towards the Synthesis of Esperamicinone (XVI). Cheminform. 26: no-no. DOI: 10.1002/chin.199511301 |
0.36 |
|
| 2010 |
NICOLAOU KC, COULADOUROS EA, NANTERMET PG, RENAUD J, GUY RK, WRASIDLO W. ChemInform Abstract: Synthesis of C-2 Taxol Analogues. Cheminform. 26: no-no. DOI: 10.1002/chin.199502148 |
0.547 |
|
| 2010 |
NICOLAOU KC, YANG Z, LIU JJ, UENO H, NANTERMET PG, GUY RK, CLAIBORNE CF, RENAUD J, COULADOUROS EA, PAULVANNAN K, SORENSEN EJ. ChemInform Abstract: Total synthesis of taxol. Cheminform. 25: no-no. DOI: 10.1002/chin.199426230 |
0.704 |
|
| 2010 |
NICOLAOU KC, CLAIBORNE CF, NANTERMET PG, COULADOUROS EA, SORENSEN EJ. ChemInform Abstract: Synthesis of Novel Taxoids. Cheminform. 25: no-no. DOI: 10.1002/chin.199426224 |
0.373 |
|
| 2010 |
NICOLAOU KC, NANTERMET PG, UENO H, GUY RK. ChemInform Abstract: Novel Chemistry of Taxol. Retrosynthetic and Synthetic Studies. Cheminform. 25: no-no. DOI: 10.1002/chin.199423201 |
0.53 |
|
| 2010 |
SMITH AL, PITSINOS EN, HWANG C, MIZUNO Y, SAIMOTO H, SCARLATO GR, SUZUKI T, NICOLAOU KC. ChemInform Abstract: Total Synthesis of Calicheamicin γI 1. Part 2. Development of an Enantioselective Route to (-)-Calicheamicinone. Cheminform. 24: no-no. DOI: 10.1002/chin.199351285 |
0.34 |
|
| 2010 |
GRONEBERG RD, MIYAZAKI T, STYLIANIDES NA, SCHULZE TJ, STAHL W, SCHREINER EP, SUZUKI T, IWABUCHI Y, SMITH AL, NICOLAOU KC. ChemInform Abstract: Total Synthesis of Calicheamicin γI 1. Part 1. Synthesis of the Oligosaccharide Fragment. Cheminform. 24: no-no. DOI: 10.1002/chin.199351284 |
0.374 |
|
| 2010 |
NICOLAOU KC, BERTINATO P, PISCOPIO AD, CHAKRABORTY TK, MINOWA N. ChemInform Abstract: Stereoselective Construction of the C21-C42 Fragment (I) of Rapamycin. Cheminform. 24: no-no. DOI: 10.1002/chin.199329273 |
0.603 |
|
| 2010 |
PISCOPIO AD, MINOWA N, CHAKRABORTY TK, KOIDE K, BERTINATO P, NICOLAOU KC. ChemInform Abstract: A Highly Convergent Strategy Towards Rapamycin. Stereoselective Construction of the C8-C18 Fragment (I). Cheminform. 24: no-no. DOI: 10.1002/chin.199329272 |
0.613 |
|
| 2010 |
NICOLAOU KC, HUMMEL CW, PITSINOS EN, NAKADA M, SMITH AL, SHIBAYAMA K, SAIMOTO H. ChemInform Abstract: Total Synthesis of Calicheamicin γ1I Cheminform. 24: no-no. DOI: 10.1002/chin.199313298 |
0.361 |
|
| 2010 |
NICOLAOU KC, ZUCCARELLO G, RIEMER C, ESTEVEZ VA, DAI W. ChemInform Abstract: Design, Synthesis, and Study of Simple Monocyclic Conjugated Enediynes. The 10-Membered Ring Enediyne Moiety of the Enediyne Anticancer Antibiotics. Cheminform. 24: no-no. DOI: 10.1002/chin.199301280 |
0.301 |
|
| 2010 |
SMITH AL, HWANG C, PITSINOS E, SCARLATO GR, NICOLAOU KC. ChemInform Abstract: Enantioselective Total Synthesis of (-)-Calicheamicinone. Cheminform. 23: no-no. DOI: 10.1002/chin.199232250 |
0.365 |
|
| 2010 |
NICOLAOU KC, HUMMEL CW, IWABUCHI Y. ChemInform Abstract: Total Synthesis of Sialyl Dimeric Lex. Cheminform. 23: no-no. DOI: 10.1002/chin.199232238 |
0.353 |
|
| 2010 |
NICOLAOU KC. ChemInform Abstract: Chemical Synthesis of Glycosphingolipids Cheminform. 22: no-no. DOI: 10.1002/chin.199152352 |
0.34 |
|
| 2010 |
NICOLAOU KC, CAULFIELD TJ, GRONEBERG RD. ChemInform Abstract: Synthesis of Novel Oligosaccharides Cheminform. 22: no-no. DOI: 10.1002/chin.199139312 |
0.372 |
|
| 2009 |
Jeso V, Nicolaou KC. Total Synthesis of Tovophyllin B. Tetrahedron Letters. 50: 1161-1163. PMID 20161287 DOI: 10.1016/J.Tetlet.2008.12.096 |
0.836 |
|
| 2009 |
Nicolaou KC, Harrison ST, Chen JS. Discoveries from the Abyss: The Abyssomicins and Their Total Synthesis. Synthesis. 2009: 33-42. PMID 20047014 DOI: 10.1055/S-0028-1083259 |
0.68 |
|
| 2009 |
Starosta AL, Qin H, Mikolajka A, Leung GY, Schwinghammer K, Nicolaou KC, Chen DY, Cooperman BS, Wilson DN. Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays. Chemistry & Biology. 16: 1087-96. PMID 19875082 DOI: 10.1016/J.Chembiol.2009.09.016 |
0.304 |
|
| 2009 |
Nicolaou KC, Li A, Edmonds DJ, Tria GS, Ellery SP. Total synthesis of platensimycin and related natural products. Journal of the American Chemical Society. 131: 16905-18. PMID 19874023 DOI: 10.1021/Ja9068003 |
0.619 |
|
| 2009 |
Nicolaou KC, Chen JS. The art of total synthesis through cascade reactions. Chemical Society Reviews. 38: 2993-3009. PMID 19847336 DOI: 10.1039/B903290H |
0.421 |
|
| 2009 |
Nicolaou KC, Tria GS, Edmonds DJ, Kar M. Total syntheses of (+/-)-platencin and (-)-platencin. Journal of the American Chemical Society. 131: 15909-17. PMID 19824676 DOI: 10.1021/Ja906801G |
0.351 |
|
| 2009 |
Nicolaou KC, Becker J, Lim YH, Lemire A, Neubauer T, Montero A. Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds. Journal of the American Chemical Society. 131: 14812-26. PMID 19778008 DOI: 10.1021/Ja9073694 |
0.796 |
|
| 2009 |
Nicolaou KC, Dalby SM, Li S, Suzuki T, Chen DY. Total synthesis of (+)-haplophytine. Angewandte Chemie (International Ed. in English). 48: 7616-20. PMID 19746386 DOI: 10.1002/anie.200904588 |
0.368 |
|
| 2009 |
Nicolaou KC, Peng XS, Sun YP, Polet D, Zou B, Lim CS, Chen DY. Total synthesis and biological evaluation of cortistatins A and J and analogues thereof. Journal of the American Chemical Society. 131: 10587-97. PMID 19722632 DOI: 10.1021/Ja902939T |
0.454 |
|
| 2009 |
Nicolaou KC, Ellery SP, Chen JS. Samarium diiodide mediated reactions in total synthesis. Angewandte Chemie (International Ed. in English). 48: 7140-65. PMID 19714695 DOI: 10.1002/Anie.200902151 |
0.445 |
|
| 2009 |
Nicolaou KC, Sarlah D, Wu TR, Zhan W. Total synthesis of hirsutellone B. Angewandte Chemie (International Ed. in English). 48: 6870-4. PMID 19685548 DOI: 10.1002/Anie.200903382 |
0.683 |
|
| 2009 |
Nicolaou KC, Li A, Ellery SP, Edmonds DJ. Rhodium-catalyzed asymmetric enyne cycloisomerization of terminal alkynes and formal total synthesis of (-)-platensimycin. Angewandte Chemie (International Ed. in English). 48: 6293-5. PMID 19606433 DOI: 10.1002/Anie.200901992 |
0.585 |
|
| 2009 |
Nicolaou KC, Nold AL, Li H. Synthesis of the monomeric unit of the lomaiviticin aglycon. Angewandte Chemie (International Ed. in English). 48: 5860-3. PMID 19575434 DOI: 10.1002/Anie.200902509 |
0.455 |
|
| 2009 |
Nicolaou KC, Ortiz A, Zhang H. The true structures of the vannusals, part 2: Total synthesis and revised structure of vannusal B. Angewandte Chemie (International Ed. in English). 48: 5648-52. PMID 19562817 DOI: 10.1002/Anie.200902029 |
0.376 |
|
| 2009 |
Nicolaou KC, Zhang H, Ortiz A. The true structures of the vannusals, part 1: Initial forays into suspected structures and intelligence gathering. Angewandte Chemie (International Ed. in English). 48: 5642-7. PMID 19562816 DOI: 10.1002/Anie.200902028 |
0.427 |
|
| 2009 |
Nicolaou KC, Wu TR, Kang Q, Chen DY. Total synthesis of hopeahainol A and hopeanol. Angewandte Chemie (International Ed. in English). 48: 3440-3. PMID 19280619 DOI: 10.1002/Anie.200900438 |
0.456 |
|
| 2009 |
Nicolaou KC, Krasovskiy A, Majumder U, Trépanier VE, Chen DY. New synthetic technologies for the construction of heterocycles and tryptamines. Journal of the American Chemical Society. 131: 3690-9. PMID 19243142 DOI: 10.1021/Ja808692J |
0.389 |
|
| 2009 |
Nicolaou KC, Tang Y, Wang J. Total synthesis of sporolide B. Angewandte Chemie (International Ed. in English). 48: 3449-53. PMID 19241430 DOI: 10.1002/Anie.200900264 |
0.533 |
|
| 2009 |
Nicolaou KC, Lim YH, Becker J. Total synthesis and absolute configuration of the bisanthraquinone antibiotic BE-43472B. Angewandte Chemie (International Ed. in English). 48: 3444-8. PMID 19235819 DOI: 10.1002/Anie.200900058 |
0.8 |
|
| 2009 |
Nicolaou KC, Reingruber R, Sarlah D, Bräse S. Enantioselective intramolecular Friedel-Crafts-type alpha-arylation of aldehydes. Journal of the American Chemical Society. 131: 2086-7. PMID 19173649 DOI: 10.1021/Ja809405C |
0.661 |
|
| 2009 |
Nicolaou KC. Inspirations, discoveries, and future perspectives in total synthesis. The Journal of Organic Chemistry. 74: 951-72. PMID 19152273 DOI: 10.1021/Jo802351B |
0.448 |
|
| 2009 |
Nicolaou KC, Chen JS, Edmonds DJ, Estrada AA. Recent advances in the chemistry and biology of naturally occurring antibiotics. Angewandte Chemie (International Ed. in English). 48: 660-719. PMID 19130444 DOI: 10.1002/Anie.200801695 |
0.739 |
|
| 2009 |
Nicolaou KC, Chen JS, Dalby SM. From nature to the laboratory and into the clinic. Bioorganic & Medicinal Chemistry. 17: 2290-303. PMID 19028103 DOI: 10.1016/J.Bmc.2008.10.089 |
0.336 |
|
| 2009 |
Nicolaou KC, Wu TR, Kang Q, Chen DY-. Synthesis of ()-Hopeanol Synfacts. 2009: 1194-1194. DOI: 10.1055/S-0029-1218028 |
0.489 |
|
| 2009 |
Nicolaou KC, Li A, Ellery SP, Edmonds DJ. Rhodium-Catalyzed Asymmetric Enyne Cycloisomerization Synfacts. 2009: 1128-1128. DOI: 10.1055/S-0029-1217850 |
0.55 |
|
| 2009 |
Nicolaou KC, Tang Y, Wang J. Synthesis of Sporolide B Synfacts. 2009: 939-939. DOI: 10.1055/S-0029-1217621 |
0.487 |
|
| 2009 |
Nicolaou KC, Dalby SM, Majumder U. Synthesis of Aspidophytine Synfacts. 2009: 591-591. DOI: 10.1055/S-0029-1216669 |
0.489 |
|
| 2009 |
Nicolaou KC, Reingruber R, Sarlah D, Bräse S. Intramolecular Friedel-Crafts-Type α-Arylationof Aldehydes Synfacts. 2009: 449-449. DOI: 10.1055/S-0028-1088099 |
0.647 |
|
| 2009 |
Nicolaou KC, Sun Y-, Peng X-, Polet D, Chen DY-. Synthesis of (+)-Cortistatin A Synfacts. 2009: 353-353. DOI: 10.1055/S-0028-1088085 |
0.49 |
|
| 2009 |
Nicolaou KC, Toh Q-, Chen DY-. Formal Synthesis of Platencin Synfacts. 2009: 245-245. DOI: 10.1055/S-0028-1087697 |
0.471 |
|
| 2009 |
Nicolaou KC, Reingruber R, Sarlah D, Bräse S. Enantioselective Intramolecular Friedel-Crafts-Type α-Arylation of Aldehydes (Journal of the American Chemical Society (2009) 131 (2086-2087)) Journal of the American Chemical Society. 131: 6640. DOI: 10.1021/Ja902682T |
0.661 |
|
| 2009 |
Nicolaou KC, Ellery SP, Chen JS. ChemInform Abstract: Samarium Diiodide Mediated Reactions in Total Synthesis Cheminform. 40: no-no. DOI: 10.1002/chin.200951228 |
0.306 |
|
| 2009 |
Nicolaou KC. ChemInform Abstract: Inspirations, Discoveries, and Future Perspectives in Total Synthesis Cheminform. 40. DOI: 10.1002/chin.200918248 |
0.352 |
|
| 2009 |
Nicolaou KC, Harrison ST, Chen JS. ChemInform Abstract: Discoveries from the Abyss: The Abyssomicins and Their Total Synthesis Cheminform. 40. DOI: 10.1002/chin.200913239 |
0.68 |
|
| 2009 |
Nicolaou KC, Lim YH, Becker J. Cover Picture: Total Synthesis and Absolute Configuration of the Bisanthraquinone Antibiotic BE-43472B (Angew. Chem. Int. Ed. 19/2009) Angewandte Chemie. 48: 3371-3371. DOI: 10.1002/Anie.200990095 |
0.779 |
|
| 2009 |
Nicolaou KC, Lim YH, Becker J. Titelbild: Total Synthesis and Absolute Configuration of the Bisanthraquinone Antibiotic BE‐43472B (Angew. Chem. 19/2009) Angewandte Chemie. 121: 3421-3421. DOI: 10.1002/Ange.200990097 |
0.753 |
|
| 2009 |
Nicolaou KC, Chen JS, Edmonds DJ, Estrada AA. Fortschritte in der Chemie und Biologie natürlicher Antibiotika Angewandte Chemie. 121: 670-732. DOI: 10.1002/Ange.200801695 |
0.686 |
|
| 2008 |
Nicolaou KC, Lister T, Denton RM, Gelin CF. Total synthesis of atrochamins F, H, I, and J through cascade reactions. Tetrahedron. 64: 4736-4757. PMID 19461992 DOI: 10.1016/J.Tet.2008.02.108 |
0.571 |
|
| 2008 |
Nicolaou KC, Dalby SM, Majumder U. A concise asymmetric total synthesis of aspidophytine. Journal of the American Chemical Society. 130: 14942-3. PMID 18855359 DOI: 10.1021/Ja806176W |
0.455 |
|
| 2008 |
Nicolaou KC, Zhang H, Ortiz A, Dagneau P. Total synthesis of the originally assigned structure of vannusal B. Angewandte Chemie (International Ed. in English). 47: 8605-10. PMID 18850598 DOI: 10.1002/Anie.200804228 |
0.815 |
|
| 2008 |
Nicolaou KC, Stepan AF, Lister T, Li A, Montero A, Tria GS, Turner CI, Tang Y, Wang J, Denton RM, Edmonds DJ. Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity. Journal of the American Chemical Society. 130: 13110-9. PMID 18771264 DOI: 10.1021/Ja8044376 |
0.715 |
|
| 2008 |
Nicolaou KC, Frederick MO, Aversa RJ. The continuing saga of the marine polyether biotoxins. Angewandte Chemie (International Ed. in English). 47: 7182-225. PMID 18763702 DOI: 10.1002/Anie.200801696 |
0.642 |
|
| 2008 |
Vilariño N, Nicolaou KC, Frederick MO, Cagide E, Alfonso C, Alonso E, Vieytes MR, Botana LM. Azaspiracid substituent at C1 is relevant to in vitro toxicity. Chemical Research in Toxicology. 21: 1823-31. PMID 18707138 DOI: 10.1021/Tx800165C |
0.323 |
|
| 2008 |
Nicolaou KC, Sun YP, Peng XS, Polet D, Chen DY. Total synthesis of (+)-cortistatin A. Angewandte Chemie (International Ed. in English). 47: 7310-3. PMID 18704899 DOI: 10.1002/Anie.200803550 |
0.473 |
|
| 2008 |
Nicolaou KC, Toh QY, Chen DY. An expedient asymmetric synthesis of platencin. Journal of the American Chemical Society. 130: 11292-3. PMID 18665593 DOI: 10.1021/Ja804588R |
0.486 |
|
| 2008 |
Nicolaou KC, Li A. Total syntheses and structural revision of alpha- and beta-diversonolic esters and total syntheses of diversonol and blennolide C. Angewandte Chemie (International Ed. in English). 47: 6579-82. PMID 18651685 DOI: 10.1002/Anie.200802632 |
0.582 |
|
| 2008 |
Nicolaou KC, Wu TR, Sarlah D, Shaw DM, Rowcliffe E, Burton DR. Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof. Journal of the American Chemical Society. 130: 11114-21. PMID 18646750 DOI: 10.1021/Ja802805C |
0.702 |
|
| 2008 |
Nicolaou KC, Leung GY, Dethe DH, Guduru R, Sun YP, Lim CS, Chen DY. Chemical synthesis and biological evaluation of palmerolide A analogues. Journal of the American Chemical Society. 130: 10019-23. PMID 18598030 DOI: 10.1021/Ja802803E |
0.803 |
|
| 2008 |
Nicolaou KC, Dethe DH, Chen DY. Total syntheses of amythiamicins A, B and C. Chemical Communications (Cambridge, England). 2632-4. PMID 18535690 DOI: 10.1039/B805069B |
0.767 |
|
| 2008 |
Nicolaou KC, Frederick MO, Burtoloso AC, Denton RM, Rivas F, Cole KP, Aversa RJ, Gibe R, Umezawa T, Suzuki T. Chemical Synthesis of the GHIJKLMNO Ring System of Maitotoxin. Journal of the American Chemical Society. 130: 7466-76. PMID 18481856 DOI: 10.1021/Ja801139F |
0.809 |
|
| 2008 |
Nicolaou KC, Krasovskiy A, Trépanier VE, Chen DY. An expedient strategy for the synthesis of tryptamines and other heterocycles. Angewandte Chemie (International Ed. in English). 47: 4217-20. PMID 18404758 DOI: 10.1002/Anie.200800404 |
0.458 |
|
| 2008 |
Nicolaou KC, Sun YP, Guduru R, Banerji B, Chen DY. Total synthesis of the originally proposed and revised structures of palmerolide A and isomers thereof. Journal of the American Chemical Society. 130: 3633-44. PMID 18298117 DOI: 10.1021/Ja710485N |
0.681 |
|
| 2008 |
Nicolaou KC, Tria GS, Edmonds DJ. Total synthesis of platencin. Angewandte Chemie (International Ed. in English). 47: 1780-3. PMID 18246566 DOI: 10.1002/anie.200800066 |
0.368 |
|
| 2008 |
Nicolaou KC, Wang J, Tang Y. Synthesis of the sporolide ring framework through a cascade sequence involving an intramolecular [4+2] cycloaddition reaction of an o-quinone. Angewandte Chemie (International Ed. in English). 47: 1432-5. PMID 18205155 DOI: 10.1002/Anie.200705334 |
0.472 |
|
| 2008 |
Nicolaou KC, Dethe DH, Leung GY, Zou B, Chen DY. Total synthesis of thiopeptide antibiotics GE2270A, GE2270T, and GE2270C1. Chemistry, An Asian Journal. 3: 413-29. PMID 18188863 DOI: 10.1002/Asia.200700361 |
0.816 |
|
| 2008 |
Nicolaou KC, Pappo D, Tsang KY, Gibe R, Chen DY. A chiral pool based synthesis of platensimycin. Angewandte Chemie (International Ed. in English). 47: 944-6. PMID 18176919 DOI: 10.1002/Anie.200705080 |
0.736 |
|
| 2008 |
Nicolaou KC, Chen JS, Zhang H, Montero A. Asymmetric synthesis and biological properties of uncialamycin and 26-epi-uncialamycin. Angewandte Chemie (International Ed. in English). 47: 185-9. PMID 18058881 DOI: 10.1002/Anie.200704577 |
0.437 |
|
| 2008 |
Nicolaou KC, Chen JS. Total synthesis of complex heterocyclic natural products Pure and Applied Chemistry. 80: 727-742. DOI: 10.1351/Pac200880040727 |
0.398 |
|
| 2008 |
Nicolaou KC, Tria GS, Edmonds DJ. Synthesis of (-)-Platencin Synfacts. 2008: 792-792. DOI: 10.1055/S-2008-1078530 |
0.478 |
|
| 2008 |
Nicolaou KC, Sun YP, Guduru R, Banerji B, Chen DY-. Synthesis of Palmerolide A Synfacts. 2008: 1022-1022. DOI: 10.1055/S-2008-1078187 |
0.682 |
|
| 2008 |
Nicolaou KC, Lister T, Denton RM, Gelin CF. Synthesis of Artochamins H, I, and J Synfacts. 2008: 120-120. DOI: 10.1055/S-2007-992495 |
0.336 |
|
| 2008 |
Nicolaou KC, Sun Y, Peng X, Polet D, Chen DY. ChemInform Abstract: Total Synthesis of (+)-Cortistatin A. Cheminform. 39. DOI: 10.1002/chin.200851203 |
0.362 |
|
| 2008 |
Nicolaou KC, Wu TR, Sarlah D, Shaw DM, Rowcliffe E, Burton DR. ChemInform Abstract: Total Synthesis, Revised Structure, and Biological Evaluation of Biyouyanagin A and Analogues Thereof. Cheminform. 39. DOI: 10.1002/chin.200850222 |
0.661 |
|
| 2008 |
Nicolaou KC, Lister T, Denton RM, Gelin CF. ChemInform Abstract: Total Synthesis of Artochamins F, H, I, and J Through Cascade Reactions. Cheminform. 39. DOI: 10.1002/chin.200840202 |
0.529 |
|
| 2008 |
Nicolaou KC, Sun Y, Guduru R, Banerji B, Chen DY. ChemInform Abstract: Total Synthesis of the Originally Proposed (I) and Revised Structures (II) of Palmerolide A and Isomers Thereof. Cheminform. 39. DOI: 10.1002/chin.200830213 |
0.574 |
|
| 2008 |
Nicolaou KC, Tria GS, Edmonds DJ. ChemInform Abstract: Total Synthesis of Platencin. Cheminform. 39. DOI: 10.1002/chin.200825211 |
0.361 |
|
| 2008 |
Nicolaou KC, Lister T, Denton RM, Gelin CF. ChemInform Abstract: Cascade Reactions Involving Formal [2 + 2] Thermal Cycloadditions: Total Synthesis of Artochamins F, H, I, and J. Cheminform. 39. DOI: 10.1002/chin.200805183 |
0.525 |
|
| 2008 |
Nicolaou K, Frederick M, Aversa R. Cover Picture: The Continuing Saga of the Marine Polyether Biotoxins (Angew. Chem. Int. Ed. 38/2008) Angewandte Chemie International Edition. 47: 7141-7141. DOI: 10.1002/Anie.200890185 |
0.565 |
|
| 2008 |
Nicolaou K, Frederick M, Aversa R. Titelbild: Die Entdeckung und Synthese von marinen Polyethern (Angew. Chem. 38/2008) Angewandte Chemie. 120: 7251-7251. DOI: 10.1002/Ange.200890239 |
0.634 |
|
| 2008 |
Nicolaou K, Frederick M, Aversa R. Die Entdeckung und Synthese von marinen Polyethern Angewandte Chemie. 120: 7292-7335. DOI: 10.1002/Ange.200801696 |
0.578 |
|
| 2007 |
Nicolaou KC, Estrada AA, Freestone GC, Lee SH, Alvarez-Mico X. New synthetic technology for the construction of N-hydroxyindoles and synthesis of nocathiacin I model systems. Tetrahedron. 63: 6088-6114. PMID 20606766 DOI: 10.1016/J.Tet.2007.03.072 |
0.726 |
|
| 2007 |
Nicolaou KC, Tang Y, Wang J, Stepan AF, Li A, Montero A. Total synthesis and antibacterial properties of carbaplatensimycin. Journal of the American Chemical Society. 129: 14850-1. PMID 17988130 DOI: 10.1021/Ja076126E |
0.612 |
|
| 2007 |
Nicolaou KC, Cole KP, Frederick MO, Aversa RJ, Denton RM. Chemical synthesis of the GHIJK ring system and further experimental support for the originally assigned structure of maitotoxin. Angewandte Chemie (International Ed. in English). 46: 8875-9. PMID 17943950 DOI: 10.1002/Anie.200703742 |
0.743 |
|
| 2007 |
Nicolaou KC, Lister T, Denton RM, Gelin CF. Cascade reactions involving formal [2+2] thermal cycloadditions: total synthesis of artochamins F, H, I, and J. Angewandte Chemie (International Ed. in English). 46: 7501-5. PMID 17768746 DOI: 10.1002/Anie.200702363 |
0.57 |
|
| 2007 |
Nicolaou KC, Tang Y, Wang J. Formal synthesis of (+/-)-platensimycin. Chemical Communications (Cambridge, England). 1922-3. PMID 17695230 DOI: 10.1039/B704589A |
0.535 |
|
| 2007 |
Nicolaou KC, Li H, Nold AL, Pappo D, Lenzen A. Total synthesis of kinamycins C, F, and J. Journal of the American Chemical Society. 129: 10356-7. PMID 17676854 DOI: 10.1021/Ja074297D |
0.734 |
|
| 2007 |
Nicolaou KC, Guduru R, Sun YP, Banerji B, Chen DY. Total synthesis of the originally proposed and revised structures of palmerolide A. Angewandte Chemie (International Ed. in English). 46: 5896-900. PMID 17600809 DOI: 10.1002/Anie.200702243 |
0.633 |
|
| 2007 |
Nicolaou KC, Majumder U, Roche SP, Chen DY. Construction of the "left domain" of haplophytine. Angewandte Chemie (International Ed. in English). 46: 4715-8. PMID 17559182 DOI: 10.1002/Anie.200701947 |
0.559 |
|
| 2007 |
Nicolaou KC, Sarlah D, Shaw DM. Total synthesis and revised structure of biyouyanagin A. Angewandte Chemie (International Ed. in English). 46: 4708-11. PMID 17523208 DOI: 10.1002/Anie.200701552 |
0.658 |
|
| 2007 |
Nicolaou KC, Lister T, Denton RM, Montero A, Edmonds DJ. Adamantaplatensimycin: a bioactive analogue of platensimycin. Angewandte Chemie (International Ed. in English). 46: 4712-4. PMID 17514775 DOI: 10.1002/Anie.200701548 |
0.593 |
|
| 2007 |
Nicolaou KC, Zhang H, Chen JS, Crawford JJ, Pasunoori L. Total synthesis and stereochemistry of uncialamycin. Angewandte Chemie (International Ed. in English). 46: 4704-7. PMID 17497617 DOI: 10.1002/Anie.200700917 |
0.714 |
|
| 2007 |
Nicolaou KC, Edmonds DJ, Li A, Tria GS. Asymmetric total syntheses of platensimycin. Angewandte Chemie (International Ed. in English). 46: 3942-5. PMID 17444571 DOI: 10.1002/Anie.200700586 |
0.583 |
|
| 2007 |
Nicolaou KC, Lim YH, Piper JL, Papageorgiou CD. Total syntheses of 2,2'-epi-cytoskyrin A, rugulosin, and the alleged structure of rugulin. Journal of the American Chemical Society. 129: 4001-13. PMID 17355133 DOI: 10.1021/Ja0685708 |
0.409 |
|
| 2007 |
Altmann KH, Pfeiffer B, Arseniyadis S, Pratt BA, Nicolaou KC. The chemistry and biology of epothilones--the wheel keeps turning. Chemmedchem. 2: 396-423. PMID 17340668 DOI: 10.1002/Cmdc.200600206 |
0.666 |
|
| 2007 |
Nicolaou KC, Nold AL, Milburn RR, Schindler CS, Cole KP, Yamaguchi J. Total synthesis of marinomycins A-C and of their monomeric counterparts monomarinomycin A and iso-monomarinomycin A. Journal of the American Chemical Society. 129: 1760-8. PMID 17249678 DOI: 10.1021/Ja068053P |
0.733 |
|
| 2007 |
Nicolaou KC, Harrison ST. Total synthesis of abyssomicin C, atrop-abyssomicin C, and abyssomicin D: implications for natural origins of atrop-abyssomicin C. Journal of the American Chemical Society. 129: 429-40. PMID 17212423 DOI: 10.1021/Ja067083P |
0.662 |
|
| 2007 |
Nicolaou KC, Pappo D, Tsang KY, Gibe R, Chen DY-. Formal Synthesis of (-)-Platensimycin Synfacts. 2007: 555-555. DOI: 10.1055/S-2008-1072610 |
0.482 |
|
| 2007 |
Nicolaou KC, Zhang H, Chen JS, Crawford JJ, Pasunoori L. Synthesis of Uncialamycin Synfacts. 2007: 1121-1121. DOI: 10.1055/S-2007-991197 |
0.712 |
|
| 2007 |
Nicolaou KC, Nold AL, Milburn RR, Schindler CS, Cole KP, Yamaguchi J. Synthesis of Marinomycin A Synfacts. 2007: 564-564. DOI: 10.1055/S-2007-968513 |
0.489 |
|
| 2007 |
Nicolaou KC, Li H, Nold AL, Pappo D, Lenzen A. Synthesis of Kinamycin C Synfacts. 2007: 344-344. DOI: 10.1055/S-2007-968285 |
0.718 |
|
| 2007 |
Nicolaou K, Li A, Edmonds D. Synthesis of (±)-Platensimycin Synfacts. 2007: 0244-0244. DOI: 10.1055/S-2007-968192 |
0.494 |
|
| 2007 |
Nicolaou KC, Tang Y, Wang J. Formal synthesis of (±)-platensimycin Chemical Communications. 1922-1923. DOI: 10.1039/C5QO00109A |
0.308 |
|
| 2007 |
Nicolaou KC, Lister T, Denton RM, Montero A, Edmonds DJ. Adamantaplatensimycin (II): A Bioactive Analogue of Platensimycin (I). Cheminform. 38. DOI: 10.1002/chin.200742200 |
0.437 |
|
| 2007 |
Nicolaou K, Sarlah D, Shaw D. Cover Picture: Total Synthesis and Revised Structure of Biyouyanagin A (Angew. Chem. Int. Ed. 25/2007) Angewandte Chemie International Edition. 46: 4587-4587. DOI: 10.1002/Anie.200790112 |
0.681 |
|
| 2007 |
Nicolaou K, Sarlah D, Shaw D. Titelbild: Total Synthesis and Revised Structure of Biyouyanagin A (Angew. Chem. 25/2007) Angewandte Chemie. 119: 4671-4671. DOI: 10.1002/Ange.200790112 |
0.691 |
|
| 2007 |
Frederick MO, Cole KP, Petrovic G, Loizidou E, Nicolaou KC. Structural Assignment and Total Synthesis of Azaspiracid-1 Phycotoxins: Chemistry and Biochemistry. 297-309. DOI: 10.1002/9780470277874.ch16 |
0.745 |
|
| 2007 |
Nicolaou KC, Ortiz A, Denton RM. Metathesis reactions in the synthesis of complex molecules Chimica Oggi. 25: 70-76. |
0.552 |
|
| 2006 |
Nicolaou KC, Frederick MO, Loizidou EZ, Petrovic G, Cole KP, Koftis TV, Yamada YM. Second-generation total synthesis of azaspiracids-1, -2, and -3. Chemistry, An Asian Journal. 1: 245-63. PMID 17441061 DOI: 10.1002/Asia.200600059 |
0.814 |
|
| 2006 |
Nicolaou KC, Edmonds DJ, Bulger PG. Cascade reactions in total synthesis Angewandte Chemie - International Edition. 45: 7134-7186. PMID 17075967 DOI: 10.1002/Anie.200601872 |
0.427 |
|
| 2006 |
Nicolaou KC, Zou B, Dethe DH, Li DB, Chen DY. Total synthesis of antibiotics GE2270A and GE2270T. Angewandte Chemie (International Ed. in English). 45: 7786-92. PMID 17061302 DOI: 10.1002/Anie.200602798 |
0.798 |
|
| 2006 |
Nicolaou KC, Li A, Edmonds DJ. Total synthesis of platensimycin. Angewandte Chemie (International Ed. in English). 45: 7086-90. PMID 17013803 DOI: 10.1002/Anie.200603892 |
0.623 |
|
| 2006 |
Nicolaou KC, Nold AL, Milburn RR, Schindler CS. Total synthesis of marinomycins A-C. Angewandte Chemie (International Ed. in English). 45: 6527-32. PMID 16977657 DOI: 10.1002/Anie.200601867 |
0.617 |
|
| 2006 |
Nicolaou KC, Pratt BA, Arseniyadis S, Wartmann M, O'Brate A, Giannakakou P. Molecular design and chemical synthesis of a highly potent epothilone Chemmedchem. 1: 41-44. PMID 16892332 DOI: 10.1002/Cmdc.200500056 |
0.716 |
|
| 2006 |
Hamel E, Day BW, Miller JH, Jung MK, Northcote PT, Ghosh AK, Curran DP, Cushman M, Nicolaou KC, Paterson I, Sorensen EJ. Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly. Molecular Pharmacology. 70: 1555-64. PMID 16887932 DOI: 10.1124/Mol.106.027847 |
0.607 |
|
| 2006 |
Nicolaou KC, Estrada AA, Sang HL, Freestone GC. Synthesis of highly substituted N-hydroxyindoles through 1,5-Addition of carbon nucleophiles to in situ generated unsaturated nitrones Angewandte Chemie - International Edition. 45: 5364-5368. PMID 16847981 DOI: 10.1002/Anie.200601808 |
0.737 |
|
| 2006 |
Hayden AE, Xu H, Nicolaou KC, Houk KN. Origins of selectivity in pericyclic reaction cascades for the synthesis of gambogin and lateriflorone. Organic Letters. 8: 2989-92. PMID 16805534 DOI: 10.1021/Ol060917O |
0.457 |
|
| 2006 |
Nicolaou KC, Bulger PG, Brenzovich WE. Synthesis of iso-epoxy-amphidinolide N and des-epoxy-caribenolide i structures. Revised strategy and final stages Organic and Biomolecular Chemistry. 4: 2158-2183. PMID 16729127 DOI: 10.1039/B602021F |
0.423 |
|
| 2006 |
Nicolaou KC, Brenzovich WE, Bulger PG, Francis TM. Synthesis of iso-epoxy-amphidinolide N and des-epoxy-caribenolide I structures. Initial forays. Organic & Biomolecular Chemistry. 4: 2119-57. PMID 16729126 DOI: 10.1039/B602020H |
0.403 |
|
| 2006 |
Nicolaou KC, Harrison ST. Total synthesis of abyssomicin C and atrop-abyssomicin C. Angewandte Chemie (International Ed. in English). 45: 3256-60. PMID 16634106 DOI: 10.1002/Anie.200601116 |
0.628 |
|
| 2006 |
Nicolaou KC, Lizos DE, Kim DW, Schlawe D, de Noronha RG, Longbottom DA, Rodriquez M, Bucci M, Cirino G. Total synthesis and biological evaluation of halipeptins A and D and analogues. Journal of the American Chemical Society. 128: 4460-70. PMID 16569024 DOI: 10.1021/Ja060064V |
0.436 |
|
| 2006 |
Nicolaou KC, Frederick MO, Petrovic G, Cole KP, Loizidou EZ. Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3. Angewandte Chemie (International Ed. in English). 45: 2609-15. PMID 16548033 DOI: 10.1002/Anie.200600295 |
0.772 |
|
| 2006 |
Nicolaou KC, Koftis TV, Vyskocil S, Petrovic G, Tang W, Frederick MO, Chen DY, Li Y, Ling T, Yamada YM. Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1. Journal of the American Chemical Society. 128: 2859-72. PMID 16506764 DOI: 10.1021/Ja054750Q |
0.83 |
|
| 2006 |
Nicolaou KC, Denton RM, Lenzen A, Edmonds DJ, Li A, Milburn RR, Harrison ST. Stereocontrolled synthesis of model core systems of lomaiviticins A and B. Angewandte Chemie (International Ed. in English). 45: 2076-81. PMID 16496276 DOI: 10.1002/Anie.200504466 |
0.763 |
|
| 2006 |
Nicolaou KC, Chen DY, Li Y, Uesaka N, Petrovic G, Koftis TV, Bernal F, Frederick MO, Govindasamy M, Ling T, Pihko PM, Tang W, Vyskocil S. Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product. Journal of the American Chemical Society. 128: 2258-67. PMID 16478179 DOI: 10.1021/Ja054748Z |
0.814 |
|
| 2006 |
Nicolaou KC, Pihko PM, Bernal F, Frederick MO, Qian W, Uesaka N, Diedrichs N, Hinrichs J, Koftis TV, Loizidou E, Petrovic G, Rodriquez M, Sarlah D, Zou N. Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure. Journal of the American Chemical Society. 128: 2244-57. PMID 16478178 DOI: 10.1021/Ja0547477 |
0.829 |
|
| 2006 |
Nicolaou KC, Xu H. Total synthesis of floresolide B and Delta(6,7)-Z-floresolide B. Chemical Communications (Cambridge, England). 600-2. PMID 16446822 DOI: 10.1039/B517385J |
0.457 |
|
| 2006 |
Nicolaou K, Harrison S. Synthesis of Abyssomicin C Synfacts. 2006: 1092-1092. DOI: 10.1055/S-2006-949397 |
0.66 |
|
| 2006 |
Nicolaou K, Lizos D, Kim D, Schlawe D, de Noronha R, Longbottom D, Rodriquez M, Bucci M, Cirino G. Synthesis of Halipeptins A and D Synfacts. 2006: 0980-0980. DOI: 10.1055/S-2006-949331 |
0.5 |
|
| 2006 |
Nicolaou K, Koftis T, Vyskocil S, Petrovic G, Tang W, Frederick M, Chen D, Ling T, Li Y, Yamada Y. Synthesis and Structural Elucidation of Azaspiracid-1 Synfacts. 2006: 0748-0748. DOI: 10.1055/S-2006-941937 |
0.828 |
|
| 2006 |
Nicolaou K, Lim Y, Papageorgiou C, Piper J. Synthesis of (+)-Rugulosin Synfacts. 2006: 0413-0413. DOI: 10.1055/S-2006-934400 |
0.478 |
|
| 2006 |
Nicolaou KC, Montagnon T, Vassilikogiannakis G, Mathison CJN. Synthesis of Coleophomone B Synfacts. 2006: 8-8. DOI: 10.1055/S-2005-921657 |
0.405 |
|
| 2006 |
Ito E, Frederick MO, Koftis TV, Tang W, Petrovic G, Ling T, Nicolaou KC. Structure toxicity relationships of synthetic azaspiracid-1 and analogs in mice Harmful Algae. 5: 586-591. DOI: 10.1016/J.Hal.2005.11.005 |
0.753 |
|
| 2006 |
Nicolaou K, Pratt B, Arseniyadis S, Wartmann M, O'Brate A, Giannakakou P. Cover Picture: Molecular Design and Chemical Synthesis of a Highly Potent Epothilone (ChemMedChem 1/2006) Chemmedchem. 1: 1-1. DOI: 10.1002/Cmdc.200690000 |
0.388 |
|
| 2006 |
Nicolaou KC, Frederick MO, Petrovic G, Cole KP, Loizidou EZ. Total Synthesis and Confirmation of the Revised Structures of Azaspiracid-2 (Ia) and Azaspiracid-3 (Ib). Cheminform. 37. DOI: 10.1002/chin.200633241 |
0.744 |
|
| 2006 |
Nicolaou KC, Claiborne CF, Paulvannan K, H. D. Postema M, Guy RK. The Chemical Synthesis of C-Ring Aryl Taxoids Chemistry - a European Journal. 3: 399-409. DOI: 10.1002/Chem.19970030311 |
0.584 |
|
| 2005 |
Nicolaou KC, Lim YH, Papageorgiou CD, Piper JL. Total synthesis of (+)-rugulosin and (+)-2,2'-epi-cytoskyrin A through cascade reactions. Angewandte Chemie (International Ed. in English). 44: 7917-21. PMID 16342134 DOI: 10.1002/Anie.200503678 |
0.415 |
|
| 2005 |
Nicolaou KC, Zak M, Rahimipour S, Estrada AA, Lee SH, O'Brate A, Giannakakou P, Ghadiri MR. Discovery of a biologically active thiostrepton fragment. Journal of the American Chemical Society. 127: 15042-4. PMID 16248640 DOI: 10.1021/Ja0552803 |
0.793 |
|
| 2005 |
Nicolaou KC, Mathison CJN. Synthesis of imides, N-acyl vinylogous carbamates and ureas, and nitriles by oxidation of amides and amines with dess-martin periodinane Angewandte Chemie - International Edition. 44: 5992-5997. PMID 16124020 DOI: 10.1002/Anie.200501853 |
0.346 |
|
| 2005 |
Nicolaou KC. Joys of molecules. 1. Campaigns in total synthesis Journal of Organic Chemistry. 70: 7007-7027. PMID 16122219 DOI: 10.1021/Jo050963M |
0.314 |
|
| 2005 |
Nicolaou KC, Zak M, Safina BS, Estrada AA, Lee SH, Nevalainen M. Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis Journal of the American Chemical Society. 127: 11176-11183. PMID 16076225 DOI: 10.1021/Ja052934Z |
0.832 |
|
| 2005 |
Nicolaou KC, Safina BS, Zak M, Lee SH, Nevalainen M, Bella M, Estrada AA, Funke C, Zécri FJ, Bulat S. Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks. Journal of the American Chemical Society. 127: 11159-75. PMID 16076224 DOI: 10.1021/Ja0529337 |
0.843 |
|
| 2005 |
Nicolaou KC, Schlawe D, Kim DW, Longbottom DA, de Noronha RG, Lizos DE, Manam RR, Faulkner DJ. Total synthesis of halipeptins: isolation of halipeptin D and synthesis of oxazoline halipeptin analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 6197-211. PMID 16075448 DOI: 10.1002/Chem.200500624 |
0.535 |
|
| 2005 |
Nicolaou KC, Kim DW, Schlawe D, Lizos DE, de Noronha RG, Longbottom DA. Total synthesis of halipeptins A and D and analogues. Angewandte Chemie (International Ed. in English). 44: 4925-9. PMID 16010700 DOI: 10.1002/Anie.200500702 |
0.523 |
|
| 2005 |
Nicolaou KC, Bulger PG, Sarlah D. Metathesis reactions in total synthesis. Angewandte Chemie (International Ed. in English). 44: 4490-527. PMID 16003791 DOI: 10.1002/Anie.200500369 |
0.677 |
|
| 2005 |
Nicolaou KC, Bulger PG, Sarlah D. Palladium-catalyzed cross-coupling reactions in total synthesis. Angewandte Chemie (International Ed. in English). 44: 4442-89. PMID 15991198 DOI: 10.1002/Anie.200500368 |
0.663 |
|
| 2005 |
Nicolaou KC, Montagnon T, Vassilikogiannakis G, Mathison CJN. The total synthesis of coleophomones B, C, and D Journal of the American Chemical Society. 127: 8872-8888. PMID 15954796 DOI: 10.1021/Ja0509984 |
0.433 |
|
| 2005 |
Nicolaou KC, Tang W, Dagneau P, Faraoni R. A catalytic asymmetric three-component 1,4-addition/aldol reaction: enantioselective synthesis of the spirocyclic system of vannusal A. Angewandte Chemie (International Ed. in English). 44: 3874-9. PMID 15900527 DOI: 10.1002/Anie.200500789 |
0.816 |
|
| 2005 |
Nicolaou KC, Sang HL, Estrada AA, Zak M. Construction of substituted N-hydroxyindoles: Synthesis of a nocathiacin I model system Angewandte Chemie - International Edition. 44: 3736-3740. PMID 15892095 DOI: 10.1002/Anie.200500724 |
0.806 |
|
| 2005 |
Nicolaou KC, Carenzi GEA, Jeso V. Construction of highly functionalized medium-sized rings: Synthesis of hyperforin and perforatumone model systems Angewandte Chemie - International Edition. 44: 3895-3899. PMID 15892032 DOI: 10.1002/Anie.200500776 |
0.803 |
|
| 2005 |
Nicolaou KC, Sasmal PK, Koftis TV, Converso A, Loizidou E, Kaiser F, Roecker AJ, Dellios CC, Sun XW, Petrovic G. Studies toward the synthesis of azadirachtin, part 2: construction of fully functionalized ABCD ring frameworks and unusual intramolecular reactions induced by close-proximity effects. Angewandte Chemie (International Ed. in English). 44: 3447-52. PMID 15849805 DOI: 10.1002/Anie.200500217 |
0.831 |
|
| 2005 |
Nicolaou KC, Sasmal PK, Roecker AJ, Sun XW, Mandal S, Converso A. Studies toward the synthesis of azadirachtin, part 1: total synthesis of a fully functionalized ABC ring framework and coupling with a norbornene domain. Angewandte Chemie (International Ed. in English). 44: 3443-7. PMID 15846829 DOI: 10.1002/Anie.200500216 |
0.822 |
|
| 2005 |
Tan C, de Noronha RG, Roecker AJ, Pyrzynska B, Khwaja F, Zhang Z, Zhang H, Teng Q, Nicholson AC, Giannakakou P, Zhou W, Olson JJ, Pereira MM, Nicolaou KC, Van Meir EG. Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway. Cancer Research. 65: 605-12. PMID 15695405 |
0.646 |
|
| 2005 |
Nicolaou KC, Snyder SA. Chasing molecules that were never there: misassigned natural products and the role of chemical synthesis in modern structure elucidation. Angewandte Chemie (International Ed. in English). 44: 1012-44. PMID 15688428 DOI: 10.1002/Anie.200460864 |
0.678 |
|
| 2005 |
Nicolaou KC, Estrada AA, Zak M, Lee SH, Safina BS. A mild and selective method for the hydrolysis of esters with trimethyltin hydroxide Angewandte Chemie - International Edition. 44: 1378-1382. PMID 15674985 DOI: 10.1002/Anie.200462207 |
0.77 |
|
| 2005 |
Nicolaou KC, Xu H, Wartmann M. Biomimetic total synthesis of gambogin and rate acceleration of pericyclic reactions in aqueous media. Angewandte Chemie (International Ed. in English). 44: 756-61. PMID 15657969 DOI: 10.1002/Anie.200462211 |
0.449 |
|
| 2005 |
Nicolaou K, Safina B, Zak M, Lee S, Navalainen M, Bella M, Estrada A, Funke C, Zecri F, Bulat S. Synthesis of Thiostrepton Synfacts. 2006: 0014-0014. DOI: 10.1055/S-2005-921667 |
0.834 |
|
| 2005 |
Nicolaou KC, Lee SH, Estrada AA, Zak M. Construction of Substituted N-Hydroxyindoles Synfacts. 2005: 199-199. DOI: 10.1055/S-2005-916069 |
0.772 |
|
| 2005 |
Nicolaou KC, Bulger PG, Sarlah D. Cover Picture: Palladium-Catalyzed Cross-Coupling Reactions in Total Synthesis / Metathesis Reactions in Total Synthesis (Angew. Chem. Int. Ed. 29/2005) Angewandte Chemie International Edition. 44: 4413-4413. DOI: 10.1002/Anie.200590098 |
0.679 |
|
| 2005 |
Nicolaou KC, Bulger PG, Sarlah D. Titelbild: Palladiumkatalysierte Kreuzkupplungen in der Totalsynthese / Metathesereaktionen in der Totalsynthese (Angew. Chem. 29/2005) Angewandte Chemie. 117: 4487-4487. DOI: 10.1002/Ange.200590097 |
0.574 |
|
| 2005 |
Nicolaou KC, Snyder SA. Die Jagd auf Moleküle, die nie existiert haben: Falsch zugeordnete Naturstoffstrukturen und die Rolle der chemischen Synthese in der modernen Strukturaufklärung Angewandte Chemie. 117: 2086-2086. DOI: 10.1002/Ange.200590046 |
0.612 |
|
| 2005 |
Nicolaou KC, Bulger PG, Sarlah D. Metathesereaktionen in der Totalsynthese Angewandte Chemie. 117: 4564-4601. DOI: 10.1002/Ange.200500369 |
0.594 |
|
| 2005 |
Nicolaou KC, Bulger PG, Sarlah D. Palladiumkatalysierte Kreuzkupplungen in der Totalsynthese Angewandte Chemie. 117: 4516-4563. DOI: 10.1002/Ange.200500368 |
0.595 |
|
| 2004 |
Nicolaou KC, Snyder SA, Longbottom DA, Nalbandian AZ, Huang X. New uses for the Burgess reagent in chemical synthesis: methods for the facile and stereoselective formation of sulfamidates, glycosylamines, and sulfamides. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 5581-606. PMID 15470695 DOI: 10.1002/Chem.200400503 |
0.682 |
|
| 2004 |
Nicolaou KC, Hao J, Reddy MV, Rao PB, Rassias G, Snyder SA, Huang X, Chen DY, Brenzovich WE, Giuseppone N, O'Brate A, Giannakakou P. Chemistry and biology of diazonamide A: second total synthesis and biological investigations. Journal of the American Chemical Society. 126: 12897-906. PMID 15469287 DOI: 10.1021/Ja040093A |
0.8 |
|
| 2004 |
Nicolaou KC, Chen DY, Huang X, Ling T, Bella M, Snyder SA. Chemistry and biology of diazonamide A: first total synthesis and confirmation of the true structure. Journal of the American Chemical Society. 126: 12888-96. PMID 15469286 DOI: 10.1021/Ja040092I |
0.824 |
|
| 2004 |
Nicolaou KC, Safina BS, Zak M, Estrada AA, Lee SH. Total synthesis of thiostrepton, part 1: construction of the dehydropiperidine/thiazoline-containing macrocycle. Angewandte Chemie (International Ed. in English). 43: 5087-92. PMID 15372631 DOI: 10.1002/Anie.200461340 |
0.832 |
|
| 2004 |
Nicolaou KC, Zak M, Safina BS, Lee SH, Estrada AA. Total synthesis of thiostrepton, part 2: construction of the quinaldic acid macrocycle and final stages of the synthesis. Angewandte Chemie (International Ed. in English). 43: 5092-7. PMID 15372630 DOI: 10.1002/Anie.200461341 |
0.818 |
|
| 2004 |
Nicolaou KC, Koftis TV, Vyskocil S, Petrovic G, Ling T, Yamada YM, Tang W, Frederick MO. Structural revision and total synthesis of azaspiracid-1, part 2: definition of the ABCD domain and total synthesis. Angewandte Chemie (International Ed. in English). 43: 4318-24. PMID 15368381 DOI: 10.1002/Anie.200460696 |
0.824 |
|
| 2004 |
Nicolaou KC, Vyskocil S, Koftis TV, Yamada YM, Ling T, Chen DY, Tang W, Petrovic G, Frederick MO, Li Y, Satake M. Structural revision and total synthesis of azaspiracid-1, part 1: intelligence gathering and tentative proposal. Angewandte Chemie (International Ed. in English). 43: 4312-8. PMID 15368380 DOI: 10.1002/Anie.200460695 |
0.818 |
|
| 2004 |
Nicolaou KC, Snyder SA, Giuseppone N, Huang X, Bella M, Reddy MV, Rao PB, Koumbis AE, O'Brate A, Giannakakou P. Studies toward diazonamide A: development of a hetero-pinacol macrocyclization cascade for the construction of the bis-macrocyclic framework of the originally proposed structure. Journal of the American Chemical Society. 126: 10174-82. PMID 15303893 DOI: 10.1021/Ja040091Q |
0.824 |
|
| 2004 |
Nicolaou KC, Snyder SA, Huang X, Simonsen KB, Koumbis AE, Bigot A. Studies toward diazonamide A: initial synthetic forays directed toward the originally proposed structure. Journal of the American Chemical Society. 126: 10162-73. PMID 15303892 DOI: 10.1021/Ja040090Y |
0.671 |
|
| 2004 |
Nicolaou KC, Snyder SA. The essence of total synthesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 11929-36. PMID 15302925 DOI: 10.1073/Pnas.0403799101 |
0.67 |
|
| 2004 |
Nicolaou KC, Snyder SA, Nalbandian AZ, Longbottom DA. A new method for the stereoselective synthesis of alpha- and beta-glycosylamines using the Burgess reagent. Journal of the American Chemical Society. 126: 6234-5. PMID 15149212 DOI: 10.1021/Ja049293C |
0.656 |
|
| 2004 |
Buey RM, Díaz JF, Andreu JM, O'Brate A, Giannakakou P, Nicolaou KC, Sasmal PK, Ritzén A, Namoto K. Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization, and cytotoxicity. Chemistry & Biology. 11: 225-36. PMID 15123284 DOI: 10.1016/J.Chembiol.2004.01.014 |
0.704 |
|
| 2004 |
Nicolaou KC, Sasmal PK, Xu H. Biomimetically inspired total synthesis and structure activity relationships of 1-O-methyllateriflorone. 6 pi electrocyclizations in organic synthesis. Journal of the American Chemical Society. 126: 5493-501. PMID 15113221 DOI: 10.1021/Ja040037+ |
0.528 |
|
| 2004 |
Nicolaou KC, Mathison CJ, Montagnon T. o-Iodoxybenzoic acid (IBX) as a viable reagent in the manipulation of nitrogen- and sulfur-containing substrates: scope, generality, and mechanism of IBX-mediated amine oxidations and dithiane deprotections. Journal of the American Chemical Society. 126: 5192-201. PMID 15099102 DOI: 10.1021/Ja0400382 |
0.791 |
|
| 2004 |
Nicolaou KC, Gray DL, Tae J. Total synthesis of hamigerans and analogues thereof. Photochemical generation and Diels-Alder trapping of hydroxy-o-quinodimethanes. Journal of the American Chemical Society. 126: 613-27. PMID 14719961 DOI: 10.1021/Ja030498F |
0.617 |
|
| 2004 |
Nicolaou KC, Gray DL. Total synthesis of hybocarpone and analogues thereof. A facile dimerization of naphthazarins to pentacyclic systems. Journal of the American Chemical Society. 126: 607-12. PMID 14719960 DOI: 10.1021/Ja030497N |
0.614 |
|
| 2004 |
Nicolaou KC, Mathison CJ, Montagnon T. New reactions of IBX: oxidation of nitrogen- and sulfur-containing substrates to afford useful synthetic intermediates. Angewandte Chemie (International Ed. in English). 42: 4077-82. PMID 12973775 DOI: 10.1002/Anie.200352076 |
0.788 |
|
| 2004 |
Nicolaou KC, Hao J, Reddy MV, Bheema Rao P, Rassias G, Snyder SA, Huang X, Chen DY, Brenzovich WE, Giuseppone N, Giannakakou P, O'Brate A. Chemistry and Biology of Diazonamide A: Second Total Synthesis and Biological Investigations [J. Am. Chem. Soc.2004,126, 12897−12906]. Journal of the American Chemical Society. 126: 15316-15316. DOI: 10.1021/Ja0408247 |
0.778 |
|
| 2004 |
Nicolaou KC, Chen DY, Huang X, Ling T, Bella M, Snyder SA. Chemistry and Biology of Diazonamide A: First Total Synthesis and Confirmation of the True Structure [J. Am. Chem. Soc.2004,126, 12888−12896]. Journal of the American Chemical Society. 126: 15316-15316. DOI: 10.1021/Ja040823E |
0.761 |
|
| 2004 |
Nicolaou KC, Snyder SA, Giuseppone N, Huang X, Bella M, Reddy MV, Bheema Rao P, Koumbis AE, Giannakakou P, O'Brate A. Studies toward Diazonamide A: Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure [J. Am. Chem. Soc.2004,126, 10174−10182]. Journal of the American Chemical Society. 126: 15316-15316. DOI: 10.1021/Ja040822M |
0.797 |
|
| 2004 |
Nicolaou KC, Koftis TV, Vyskocil S, Petrovic G, Ling T, Yamada YMA, Tang W, Frederick MO. Structural Revision and Total Synthesis of Azaspiracid-1. Part 2. Definition of the ABCD Domain and Total Synthesis. Cheminform. 35. DOI: 10.1002/chin.200447211 |
0.713 |
|
| 2004 |
Nicolaou KC, Snyder SA, Nalbandian AZ, Longbottom DA. A New Method for the Stereoselective Synthesis of α- and β-Glycosylamines Using the Burgess Reagent. Cheminform. 35. DOI: 10.1002/chin.200439173 |
0.602 |
|
| 2004 |
Nicolaou KC, Vyskocil S, Koftis TV, Yamada YMA, Ling T, Chen DY, Tang W, Petrovic G, Frederick MO, Li Y, Satake M. Cover Picture: Structural Revision and Total Synthesis of Azaspiracid-1, Part 1: Intelligence Gathering and Tentative Proposal (Angew. Chem. Int. Ed. 33/2004) Angewandte Chemie International Edition. 43: 4239-4239. DOI: 10.1002/Anie.200490111 |
0.805 |
|
| 2004 |
Nicolaou KC, Vyskocil S, Koftis TV, Yamada YMA, Ling T, Chen DY, Tang W, Petrovic G, Frederick MO, Li Y, Satake M. Titelbild: Structural Revision and Total Synthesis of Azaspiracid-1, Part 1: Intelligence Gathering and Tentative Proposal (Angew. Chem. 33/2004) Angewandte Chemie. 116: 4335-4335. DOI: 10.1002/Ange.200490110 |
0.807 |
|
| 2003 |
Nicolaou KC, Kim DW, Baati R, O'Brate A, Giannakakou P. Total synthesis and biological evaluation of (-)apicularen A and analogues thereof. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 6177-91. PMID 14679529 DOI: 10.1002/Chem.200305230 |
0.585 |
|
| 2003 |
Nicolaou KC, Li Y, Sugita K, Monenschein H, Guntupalli P, Mitchell HJ, Fylaktakidou KC, Vourloumis D, Giannakakou P, O'Brate A. Total synthesis of apoptolidin: completion of the synthesis and analogue synthesis and evaluation. Journal of the American Chemical Society. 125: 15443-54. PMID 14664590 DOI: 10.1021/Ja030496V |
0.754 |
|
| 2003 |
Nicolaou KC, Fylaktakidou KC, Monenschein H, Li Y, Weyershausen B, Mitchell HJ, Wei HX, Guntupalli P, Hepworth D, Sugita K. Total synthesis of apoptolidin: construction of enantiomerically pure fragments. Journal of the American Chemical Society. 125: 15433-42. PMID 14664589 DOI: 10.1021/Ja0304953 |
0.749 |
|
| 2003 |
Nicolaou KC, Sasmal PK, Xu H, Namoto K, Ritzén A. Total synthesis of 1-O-methyllateriflorone. Angewandte Chemie (International Ed. in English). 42: 4225-9. PMID 14502742 DOI: 10.1002/Anie.200351805 |
0.746 |
|
| 2003 |
Nicolaou KC, Evans RM, Roecker AJ, Hughes R, Downes M, Pfefferkorn JA. Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries. Organic & Biomolecular Chemistry. 1: 908-20. PMID 12929628 DOI: 10.1039/B300525A |
0.81 |
|
| 2003 |
Nicolaou KC, Chen DY, Li Y, Qian W, Ling T, Vyskocil S, Koftis TV, Govindasamy M, Uesaka N. Total synthesis of the proposed azaspiracid-1 structure, part 2: coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis. Angewandte Chemie (International Ed. in English). 42: 3649-53. PMID 12916037 DOI: 10.1002/Anie.200351826 |
0.668 |
|
| 2003 |
Nicolaou KC, Li Y, Uesaka N, Koftis TV, Vyskocil S, Ling T, Govindasamy M, Qian W, Bernal F, Chen DY. Total synthesis of the proposed azaspiracid-1 structure, part 1: construction of the enantiomerically pure C1-C20, C21-C27, and C28-C40 fragments. Angewandte Chemie (International Ed. in English). 42: 3643-8. PMID 12916036 DOI: 10.1002/Anie.200351825 |
0.761 |
|
| 2003 |
Nicolaou KC, Roecker AJ, Monenschein H, Guntupalli P, Follmann M. Studies towards the synthesis of azadirachtin: enantioselective entry into the azadirachtin framework through cascade reactions. Angewandte Chemie (International Ed. in English). 42: 3637-42. PMID 12916035 DOI: 10.1002/Anie.200351744 |
0.738 |
|
| 2003 |
Nicolaou KC, Sasmal PK, Rassias G, Reddy MV, Altmann KH, Wartmann M, O'Brate A, Giannakakou P. Design, synthesis, and biological properties of highly potent epothilone B analogues Angewandte Chemie - International Edition. 42: 3515-3520. PMID 12900969 DOI: 10.1002/Anie.200351819 |
0.392 |
|
| 2003 |
Nicolaou KC, Nevalainen M, Zak M, Bulat S, Bella M, Safina BS. Synthetic studies on thiostrepton: construction of thiostrepton analogues with the thiazoline-containing macrocycle. Angewandte Chemie (International Ed. in English). 42: 3418-24. PMID 12888975 DOI: 10.1002/Anie.200351745 |
0.813 |
|
| 2003 |
Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM. A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. Molecular Cell. 11: 1079-92. PMID 12718892 DOI: 10.1016/S1097-2765(03)00104-7 |
0.746 |
|
| 2003 |
Nicolaou KC, Bheema Rao P, Hao J, Reddy MV, Rassias G, Huang X, Chen DY, Snyder SA. The second total synthesis of diazonamide A. Angewandte Chemie (International Ed. in English). 42: 1753-8. PMID 12707898 DOI: 10.1002/Anie.200351112 |
0.718 |
|
| 2003 |
Nicolaou KC, Montagnon T, Snyder SA. Tandem reactions, cascade sequences, and biomimetic strategies in total synthesis. Chemical Communications (Cambridge, England). 551-64. PMID 12669826 DOI: 10.1039/B209440C |
0.695 |
|
| 2003 |
Nicolaou KC, Roecker AJ, Hughes R, van Summeren R, Pfefferkorn JA, Winssinger N. Novel strategies for the solid phase synthesis of substituted indolines and indoles. Bioorganic & Medicinal Chemistry. 11: 465-76. PMID 12517442 DOI: 10.1016/S0968-0896(02)00386-3 |
0.815 |
|
| 2003 |
Nicolaou KC, Montagnon T, Vassilikogiannakis G. Total Synthesis of Coleophomone D. Cheminform. 34. DOI: 10.1039/B208236P |
0.412 |
|
| 2003 |
Nicolaou KC. Perspectives in total synthesis: a personal account Tetrahedron. 59: 6683-6738. DOI: 10.1016/S0040-4020(03)00943-8 |
0.405 |
|
| 2003 |
Nicolaou KC, Li Y, Uesaka N, Koftis TV, Vyskocil S, Ling T, Govindasamy M, Qian W, Bernal F, Chen DY. Total Synthesis of the Proposed Azaspiracid-1 Structure (I). Part 1. Construction of the Enantiomerically Pure C1—C20, C21—C27, and C28—C40 Fragments. Cheminform. 34. DOI: 10.1002/chin.200346216 |
0.522 |
|
| 2003 |
Nicolaou KC, Kim DW, Baati R. Stereocontrolled Total Synthesis of Apicularen A (I) and Its Δ17,18 Z Isomer. Cheminform. 34. DOI: 10.1002/chin.200305219 |
0.521 |
|
| 2002 |
Nicolaou KC, Montagnon T, Baran PS. HIO3 and I2O5: mild and selective alternative reagents to IBX for the dehydrogenation of aldehydes and ketones. Angewandte Chemie (International Ed. in English). 41: 1386-9. PMID 19750773 DOI: 10.1002/1521-3773(20020415)41:8<1386::Aid-Anie1386>3.0.Co;2-V |
0.629 |
|
| 2002 |
Nicolaou KC, Snyder SA, Montagnon T, Vassilikogiannakis G. The Diels--Alder reaction in total synthesis. Angewandte Chemie (International Ed. in English). 41: 1668-98. PMID 19750686 DOI: 10.1002/1521-3773(20020517)41:10<1668::Aid-Anie1668>3.0.Co;2-Z |
0.69 |
|
| 2002 |
Nicolaou KC, Nevalainen M, Safina BS, Zak M, Bulat S. A biomimetically inspired synthesis of the dehydropiperidine domain of thiostrepton. Angewandte Chemie (International Ed. in English). 41: 1941-5. PMID 19750640 DOI: 10.1002/1521-3773(20020603)41:11<1941::Aid-Anie1941>3.0.Co;2-V |
0.796 |
|
| 2002 |
Nicolaou KC, Safina BS, Funke C, Zak M, Zécri FJ. Stereocontrolled synthesis of the quinaldic acid macrocyclic system of thiostrepton. Angewandte Chemie (International Ed. in English). 41: 1937-40. PMID 19750639 DOI: 10.1002/1521-3773(20020603)41:11<1937::Aid-Anie1937>3.0.Co;2-Y |
0.811 |
|
| 2002 |
Nicolaou KC, Roecker AJ, Follmann M, Baati R. Model studies towards azadirachtin: part 2. Construction of the crowded C8-C14 bond by transition metal chemistry. Angewandte Chemie (International Ed. in English). 41: 2107-10. PMID 19746611 DOI: 10.1002/1521-3773(20020617)41:12<2107::Aid-Anie2107>3.0.Co;2-4 |
0.656 |
|
| 2002 |
Nicolaou KC, Follmann M, Roecker AJ, Hunt KW. Model studies towards azadirachtin: part 1. Construction of the crowded C8-C14 bond by radical chemistry. Angewandte Chemie (International Ed. in English). 41: 2103-6. PMID 19746610 DOI: 10.1002/1521-3773(20020617)41:12<2103::Aid-Anie2103>3.0.Co;2-S |
0.675 |
|
| 2002 |
Nicolaou KC, Huang X, Snyder SA, Bheema Rao P, Bella M, Reddy MV. A novel regio- and stereoselective synthesis of sulfamidates from 1,2-diols using Burgess and related reagents: a facile entry into beta-amino alcohols. Angewandte Chemie (International Ed. in English). 41: 834-8. PMID 12491352 DOI: 10.1002/1521-3773(20020301)41:5<834::Aid-Anie834>3.0.Co;2-V |
0.726 |
|
| 2002 |
Nicolaou KC, Gray DL, Montagnon T, Harrison ST. Oxidation of silyl enol ethers by using IBX and IBX.N-oxide complexes: a mild and selective reaction for the synthesis of enones. Angewandte Chemie (International Ed. in English). 41: 996-1000. PMID 12491292 DOI: 10.1002/1521-3773(20020315)41:6<996::Aid-Anie996>3.0.Co;2-I |
0.697 |
|
| 2002 |
Nicolaou KC, Montagnon T, Baran PS. Modulation of the reactivity profile of IBX by ligand complexation: ambient temperature dehydrogenation of aldehydes and ketones to alpha,beta-unsaturated carbonyl compounds. Angewandte Chemie (International Ed. in English). 41: 993-6. PMID 12491291 DOI: 10.1002/1521-3773(20020315)41:6<993::Aid-Anie993>3.0.Co;2-U |
0.624 |
|
| 2002 |
Nicolaou KC, Longbottom DA, Snyder SA, Nalbanadian AZ, Huang X. A new method for the synthesis of nonsymmetrical sulfamides using burgess-type reagents. Angewandte Chemie (International Ed. in English). 41: 3866-70. PMID 12386873 DOI: 10.1002/1521-3773(20021018)41:20<3866::Aid-Anie3866>3.0.Co;2-T |
0.666 |
|
| 2002 |
Nicolaou KC, Kim DW, Baati R. Stereocontrolled total synthesis of apicularen A and its delta(17,18) Z isomer. Angewandte Chemie (International Ed. in English). 41: 3701-4; 3523. PMID 12370936 DOI: 10.1002/1521-3773(20021004)41:19<3701::Aid-Anie3701>3.0.Co;2-4 |
0.574 |
|
| 2002 |
Nicolaou KC, Bella M, Chen DY, Huang X, Ling T, Snyder SA. Total synthesis of diazonamide A. Angewandte Chemie (International Ed. in English). 41: 3495-9. PMID 12298077 DOI: 10.1002/1521-3773(20020916)41:18<3495::Aid-Anie3495>3.0.Co;2-7 |
0.83 |
|
| 2002 |
Wrasidlo W, Gaedicke G, Guy RK, Renaud J, Pitsinos E, Nicolaou KC, Reisfeld RA, Lode HN. A novel 2'-(N-methylpyridinium acetate) prodrug of paclitaxel induces superior antitumor responses in preclinical cancer models. Bioconjugate Chemistry. 13: 1093-9. PMID 12236791 DOI: 10.1021/Bc0200226 |
0.45 |
|
| 2002 |
Nicolaou KC, Vassilikogiannakis G, Montagnon T. The total synthesis of coleophomones B and C. Angewandte Chemie (International Ed. in English). 41: 3276-81. PMID 12207414 DOI: 10.1002/1521-3773(20020902)41:17<3276::Aid-Anie3276>3.0.Co;2-P |
0.441 |
|
| 2002 |
Nicolaou KC, Baran PS. The CP molecule labyrinth: a paradigm of how endeavors in total synthesis lead to discoveries and inventions in organic synthesis. Angewandte Chemie (International Ed. in English). 41: 2678-720. PMID 12203464 DOI: 10.1002/1521-3773(20020802)41:15<2678::Aid-Anie2678>3.0.Co;2-V |
0.709 |
|
| 2002 |
Nicolaou KC, Boddy CN. Atropselective macrocyclization of diaryl ether ring systems: application to the synthesis of vancomycin model systems. Journal of the American Chemical Society. 124: 10451-5. PMID 12197747 DOI: 10.1021/Ja020736R |
0.69 |
|
| 2002 |
Nicholas GM, Eckman LL, Ray S, Hughes RO, Pfefferkorn JA, Barluenga S, Nicolaou KC, Bewley CA. Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase. Bioorganic & Medicinal Chemistry Letters. 12: 2487-90. PMID 12161164 DOI: 10.1016/S0960-894X(02)00385-2 |
0.799 |
|
| 2002 |
Nicolaou KC, Montagnon T, Ulven T, Baran PS, Zhong YL, Sarabia F. Novel chemistry of alpha-tosyloxy ketones: applications to the solution- and solid-phase synthesis of privileged heterocycle and enediyne libraries. Journal of the American Chemical Society. 124: 5718-28. PMID 12010045 DOI: 10.1021/ja012146j |
0.629 |
|
| 2002 |
Nicolaou KC, Montagnon T, Baran PS, Zhong YL. Iodine(V) reagents in organic synthesis. Part 4. o-Iodoxybenzoic acid as a chemospecific tool for single electron transfer-based oxidation processes. Journal of the American Chemical Society. 124: 2245-58. PMID 11878978 DOI: 10.1021/ja012127+ |
0.601 |
|
| 2002 |
Nicolaou KC, Baran PS, Zhong YL, Barluenga S, Hunt KW, Kranich R, Vega JA. Iodine(V) reagents in organic synthesis. Part 3. New routes to heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: generality, scope, and mechanism. Journal of the American Chemical Society. 124: 2233-44. PMID 11878977 DOI: 10.1021/ja012126h |
0.764 |
|
| 2002 |
Nicolaou KC, Sugita K, Baran PS, Zhong YL. Iodine(V) reagents in organic synthesis. Part 2. Access to complex molecular architectures via Dess-Martin periodinane-generated o-imidoquinones. Journal of the American Chemical Society. 124: 2221-32. PMID 11878976 DOI: 10.1021/ja012125p |
0.641 |
|
| 2002 |
Nicolaou KC, Baran PS, Zhong YL, Sugita K. Iodine(V) reagents in organic synthesis. Part 1. Synthesis of polycyclic heterocycles via Dess-Martin periodinane-mediated cascade cyclization: generality, scope, and mechanism of the reaction. Journal of the American Chemical Society. 124: 2212-20. PMID 11878975 DOI: 10.1021/ja012124x |
0.656 |
|
| 2002 |
Nicolaou KC, Zhong YL, Baran PS, Jung J, Choi HS, Yoon WH. Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 3. Completion and synthesis of advanced analogues. Journal of the American Chemical Society. 124: 2202-11. PMID 11878974 DOI: 10.1021/ja0120126 |
0.758 |
|
| 2002 |
Nicolaou KC, Baran PS, Zhong YL, Fong KC, Choi HS. Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 2. Model studies for the construction of key structural elements and first-generation strategy. Journal of the American Chemical Society. 124: 2190-201. PMID 11878973 DOI: 10.1021/ja012011d |
0.624 |
|
| 2002 |
Nicolaou KC, Jung J, Yoon WH, Fong KC, Choi HS, He Y, Zhong YL, Baran PS. Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo[4.3.1] key building blocks. Journal of the American Chemical Society. 124: 2183-9. PMID 11878972 DOI: 10.1021/ja012010l |
0.76 |
|
| 2002 |
Schreiber SL, Nicolaou KC, Davies K. Diversity-oriented organic synthesis and proteomics. New frontiers for chemistry & biology. Chemistry & Biology. 9: 1-2. PMID 11841933 DOI: 10.1016/S1074-5521(02)00088-1 |
0.331 |
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| 2002 |
Nicolaou KC, Vassilikogiannakis G, Mägerlein W, Kranich R. Total synthesis of colombiasin A and determination of its absolute configuration. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 5359-71. PMID 11822436 DOI: 10.1002/1521-3765(20011217)7:24<5359::Aid-Chem5359>3.0.Co;2-Z |
0.453 |
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| 2002 |
Nicolaou KC, Jennings MP, Dagneau P. An expedient entry into the fused polycyclic skeleton of vannusal A Chemical Communications. 8: 2480-2481. DOI: 10.1039/B208234A |
0.818 |
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| 2002 |
Nicolaou KC, Ritzén A, Namoto K, Buey RM, Díaz JF, Andreu JM, Wartmann M, Altmann KH, O'Brate A, Giannakakou P. Chemical synthesis and biological evaluation of novel epothilone B and trans-12,13-cyclopropyl epothilone B analogues Tetrahedron. 58: 6413-6432. DOI: 10.1016/S0040-4020(02)00655-5 |
0.769 |
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| 2002 |
Nicolaou KC, Baran PS. Cover Picture: Angew. Chem. Int. Ed. 15/2002 Angewandte Chemie International Edition. 41: 2619-2619. DOI: 10.1002/1521-3773(20020802)41:15<2619::Aid-Anie2619>3.0.Co;2-0 |
0.646 |
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| 2002 |
Nicolaou KC, Nevalainen M, Safina BS, Zak M, Bulat S. A Biomimetically Inspired Synthesis of the Dehydropiperidine Domain of Thiostrepton We thank Drs. D. H. Huang and L. Pasternack, G. Suizdak, and R. Chadja for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), fellowships from The Academy of Finland (M.N.), The Skaggs Institute for Research (M.Z.), and Bayer AG (S.B.), and grants from Abbott, Amgen, Array Biopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie International Edition. 41: 1941. DOI: 10.1002/1521-3773(20020603)41:11<1941::AID-ANIE1941>3.0.CO;2-V |
0.666 |
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| 2002 |
Nicolaou KC, Safina BS, Funke C, Zak M, Zécri FJ. Stereocontrolled Synthesis of the Quinaldic Acid Macrocyclic System of Thiostrepton We thank Drs. D. H. Huang and G. Suizdak for NMR spectroscopic and mass spectrometric assistance, respectively, as well as Mike Sertic (University of California, San Diego) for experimental assistance. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), fellowships from The Skaggs Institute for Research (to M.Z. and F.Z.), and grants from Abbott, Amgen, Array Biopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie International Edition. 41: 1937. DOI: 10.1002/1521-3773(20020603)41:11<1937::AID-ANIE1937>3.0.CO;2-Y |
0.669 |
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| 2002 |
Corey EJ, Nicolaou KC, Snyder SA, Montagnon T, Vassilikogiannakis G. Cover Picture: Angew. Chem. Int. Ed. 10/2002 Angewandte Chemie International Edition. 41: 1629-1629. DOI: 10.1002/1521-3773(20020517)41:10<1629::Aid-Anie1629>3.0.Co;2-0 |
0.718 |
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| 2002 |
Nicolaou KC, Baran PS. Das Labyrinth der CP-Verbindungen: ein Musterbeispiel dafür, wie Bemühungen in der Totalsynthese zu Entdeckungen und Erfindungen in der Organischen Synthese führen Angewandte Chemie. 114: 2800-2843. DOI: 10.1002/1521-3757(20020802)114:15<2800::Aid-Ange2800>3.0.Co;2-B |
0.605 |
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| 2002 |
Nicolaou KC, Baran PS. Titelbild: Angew. Chem. 15/2002 Angewandte Chemie. 114: 2739-2739. DOI: 10.1002/1521-3757(20020802)114:15<2739::Aid-Ange2739>3.0.Co;2-V |
0.567 |
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| 2002 |
Nicolaou KC, Snyder SA, Montagnon T, Vassilikogiannakis GE. Die Diels-Alder-Reaktion in der Totalsynthese Angewandte Chemie. 114: 1742-1773. DOI: 10.1002/1521-3757(20020517)114:10<1742::Aid-Ange1742>3.0.Co;2-Y |
0.605 |
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| 2002 |
Corey EJ, Nicolaou KC, Snyder SA, Montagnon T, Vassilikogiannakis GE. Titelbild: Angew. Chem. 10/2002 Angewandte Chemie. 114: 1703-1703. DOI: 10.1002/1521-3757(20020517)114:10<1703::Aid-Ange1703>3.0.Co;2-# |
0.684 |
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| 2001 |
Nicolaou KC, Qian W, Bernal F, Uesaka N, Pihko PM, Hinrichs J. Synthesis of the ABCD Ring System of Azaspiracid. Angewandte Chemie (International Ed. in English). 40: 4068-4071. PMID 29712267 DOI: 10.1002/1521-3773(20011105)40:21<4068::AID-ANIE4068>3.0.CO;2-Y |
0.735 |
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| 2001 |
Nicolaou KC, Zhong YL, Baran PS, Sugita K. Rapid Access to Complex Molecular Architectures via o-Azaquinones. Angewandte Chemie (International Ed. in English). 40: 2145-2149. PMID 29712189 DOI: 10.1002/1521-3773(20010601)40:11<2145::Aid-Anie2145>3.0.Co;2-M |
0.606 |
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| 2001 |
Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and Completion of the Synthesis. Angewandte Chemie (International Ed. in English). 40: 3854-3857. PMID 29712136 DOI: 10.1002/1521-3773(20011015)40:20<3854::Aid-Anie3854>3.0.Co;2-D |
0.752 |
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| 2001 |
Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei HX, Weyershausen B. Total Synthesis of Apoptolidin: Part 1. Retrosynthetic Analysis and Construction of Building Blocks. Angewandte Chemie (International Ed. in English). 40: 3849-3854. PMID 29712121 DOI: 10.1002/1521-3773(20011015)40:20<3849::Aid-Anie3849>3.0.Co;2-M |
0.737 |
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| 2001 |
Nicolaou KC, Li J. "Biomimetic" Cascade Reactions in Organic Synthesis: Construction of 4-Oxatricyclo[4.3.1.0]decan-2-one Systems and Total Synthesis of 1-O-Methylforbesione via Tandem Claisen Rearrangement/Diels-Alder Reactions. Angewandte Chemie (International Ed. in English). 40: 4264-4268. PMID 29712093 DOI: 10.1002/1521-3773(20011119)40:22<4264::Aid-Anie4264>3.0.Co;2-1 |
0.601 |
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| 2001 |
Nicolaou KC, Baran PS, Kranich R, Zhong YL, Sugita K, Zou N. Mechanistic Studies of Periodinane-Mediated Reactions of Anilides and Related Systems. Angewandte Chemie (International Ed. in English). 40: 202-206. PMID 29711956 DOI: 10.1002/1521-3773(20010105)40:1<202::Aid-Anie202>3.0.Co;2-3 |
0.597 |
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| 2001 |
Nicolaou KC, Sugita K, Baran PS, Zhong YL. New Synthetic Technology for the Construction of N-Containing Quinones and Derivatives Thereof: Total Synthesis of Epoxyquinomycin B. Angewandte Chemie (International Ed. in English). 40: 207-210. PMID 29711950 DOI: 10.1002/1521-3773(20010105)40:1<207::Aid-Anie207>3.0.Co;2-K |
0.662 |
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| 2001 |
Nicolaou KC, Qian W, Bernal F, Uesaka N, Pihko PM, Hinrichs J. Synthesis of the ABCD Ring System of Azaspiracid We thank Drs. D. H. Huang and G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), The Skaggs Institute for Chemical Biology, a predoctoral fellowship from Bristol-Myers Squibb (to F.B.), postdoctoral fellowships from The Skaggs Institute for Research (to W.Q.), the Academy of Finland, the Ella and Georg Ehrnrooth Foundation and the Tauno Tönning Foundation (all to P.M.P.), and Bayer AG (to J.H.), as well as grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 4068-4071. PMID 12404495 DOI: 10.1002/1521-3773(20011105)40:21<4068::AID-ANIE4068>3.0.CO;2-Y |
0.702 |
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| 2001 |
Nicolaou KC, Huang X, Giuseppone N, Bheema Rao P, Bella M, Reddy MV, Snyder SA. Construction of the Complete Aromatic Core of Diazonamide A by a Novel Hetero Pinacol Macrocyclization Cascade Reaction We thank Drs. D. H. Huang and G. Suizdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), American Biosciences, a predoctoral fellowship from the National Science Foundation (S.A.S.), a postdoctoral fellowship from the Association pour la Recherche sur le Cancer (N.G.), and grants from Abbott, Amgen, Array Biopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 4705-4709. PMID 12404390 DOI: 10.1002/1521-3773(20011217)40:24<4705::Aid-Anie4705>3.0.Co;2-D |
0.778 |
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| 2001 |
Nicolaou KC, Ritzén A, Namoto K. Recent developments in the chemistry, biology and medicine of the epothilones. Chemical Communications (Cambridge, England). 1523-35. PMID 12240368 DOI: 10.1039/B104949F |
0.754 |
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| 2001 |
Nicolaou KC, Roecker AJ, Barluenga S, Pfefferkorn JA, Cao GQ. Discovery of novel antibacterial agents active against methicillin-resistant Staphylococcus aureus from combinatorial benzopyran libraries. Chembiochem : a European Journal of Chemical Biology. 2: 460-5. PMID 11828478 DOI: 10.1002/1439-7633(20010601)2:6<460::Aid-Cbic460>3.0.Co;2-2 |
0.779 |
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| 2001 |
Nicolaou KC, Namoto K, Li J, Ritzén A, Ulven T, Shoji M, Zaharevitz D, Gussio R, Sackett DL, Ward RD, Hensler A, Fojo T, Giannakakou P. Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones. Chembiochem : a European Journal of Chemical Biology. 2: 69-75. PMID 11828429 DOI: 10.1002/1439-7633(20010105)2:1<69::Aid-Cbic69>3.0.Co;2-8 |
0.814 |
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| 2001 |
Nicolaou KC, Pfefferkorn JA. Solid phase synthesis of complex natural products and libraries thereof. Biopolymers. 60: 171-93. PMID 11774224 DOI: 10.1002/1097-0282(2001)60:3<171::Aid-Bip10030>3.0.Co;2-M |
0.653 |
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| 2001 |
Newman RA, Yang J, Raymond M, Finlay V, Cabral F, Vourloumis D, Stephens LC, Troncoso P, Wu X, Logothetis CJ, Nicolaou KC, Navone NM. Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts. Cancer Chemotherapy and Pharmacology. 48: 319-26. PMID 11710633 DOI: 10.1007/S002800100323 |
0.318 |
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| 2001 |
Nicolaou KC, Hughes R, Pfefferkorn JA, Barluenga S. Optimization and mechanistic studies of psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA). Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 4296-310. PMID 11686610 DOI: 10.1002/1521-3765(20011001)7:19<4296::Aid-Chem4296>3.0.Co;2-2 |
0.817 |
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| 2001 |
Nicolaou KC, Hughes R, Pfefferkorn JA, Barluenga S, Roecker AJ. Combinatorial synthesis through disulfide exchange: discovery of potent psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA). Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 4280-95. PMID 11686609 DOI: 10.1002/1521-3765(20011001)7:19<4280::Aid-Chem4280>3.0.Co;2-3 |
0.809 |
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| 2001 |
Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and Completion of the Synthesis We thank Dr. C. Khosla and Dr. Y. Hayakawa for generous gifts of apoptolidin, and Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), the Skaggs Institute for Chemical Biology, American Biosciences, a predoctoral fellowship from Boehringer Ingelheim (to Y.L.), a postdoctoral fellowship the George Hewitt Foundation (to K.C.F.), and grants from Abbott Laboratories, ArrayBiopharma, Bayer, Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 3854-3857. PMID 11668554 DOI: 10.1002/1521-3773(20011015)40:20<3854::AID-ANIE3854>3.0.CO;2-D |
0.675 |
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| 2001 |
Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei HX, Weyershausen B. Total Synthesis of Apoptolidin: Part 1. Retrosynthetic Analysis and Construction of Building Blocks We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), the Skaggs Institute for Chemical Biology, American Biosciences, a pre-doctoral fellowship from Boehringer Ingelheim (Y.L.), a postdoctoral fellowship the George Hewitt Foundation (K.C.F.), and grants from Abbott Laboratories, ArrayBiopharma, Bayer, Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 3849-3854. PMID 11668553 DOI: 10.1002/1521-3773(20011015)40:20<3849::AID-ANIE3849>3.0.CO;2-M |
0.651 |
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| 2001 |
Nicolaou KC, Gray D, Tae J. Total Synthesis of Hamigerans: Part 2. Implementation of the Intramolecular Diels-Alder Trapping of Photochemically Generated Hydroxy-o-quinodimethanes; Strategy and Completion of the Synthesis This work was financially supported by the National Institutes of Health (USA) and The Skaggs Institute for Chemical Biology, and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 3679-3683. PMID 11592220 DOI: 10.1002/1521-3773(20011001)40:19<3679::Aid-Anie3679>3.0.Co;2-T |
0.571 |
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| 2001 |
Nicolaou KC, Gray D, Tae J. Total Synthesis of Hamigerans: Part 1. Development of Synthetic Technology for the Construction of Benzannulated Polycyclic Systems by the Intramolecular Trapping of Photogenerated Hydroxy-o-quinodimethanes and Synthesis of Key Building Blocks This work was financially supported by the National Institutes of Health (USA) and The Skaggs Institute for Chemical Biology, and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 3675-3678. PMID 11592219 DOI: 10.1002/1521-3773(20011001)40:19<3675::Aid-Anie3675>3.0.Co;2-G |
0.573 |
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| 2001 |
Nicolaou KC, Hughes R, Cho SY, Winssinger N, Labischinski H, Endermann R. Synthesis and biological evaluation of vancomycin dimers with potent activity against vancomycin-resistant bacteria: target-accelerated combinatorial synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 3824-43. PMID 11575783 DOI: 10.1002/1521-3765(20010903)7:17<3824::Aid-Chem3824>3.0.Co;2-1 |
0.722 |
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| 2001 |
Nicolaou KC, Cho SY, Hughes R, Winssinger N, Smethurst C, Labischinski H, Endermann R. Solid- and solution-phase synthesis of vancomycin and vancomycin analogues with activity against vancomycin-resistant bacteria. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 3798-823. PMID 11575782 DOI: 10.1002/1521-3765(20010903)7:17<3798::Aid-Chem3798>3.0.Co;2-6 |
0.686 |
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| 2001 |
Nicolaou KC, Namoto K, Ritzén A, Ulven T, Shoji M, Li J, D'Amico G, Liotta D, French CT, Wartmann M, Altmann KH, Giannakakou P. Chemical synthesis and biological evaluation of cis- and trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues. Journal of the American Chemical Society. 123: 9313-23. PMID 11562214 DOI: 10.1021/Ja011338B |
0.801 |
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| 2001 |
Nicolaou KC, Baran PS, Zhong YL. Selective oxidation at carbon adjacent to aromatic systems with IBX. Journal of the American Chemical Society. 123: 3183-5. PMID 11457049 DOI: 10.1021/Ja004218X |
0.575 |
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| 2001 |
Nicolaou KC, Zhong YL, Baran PS, Sugita K. Rapid Access to Complex Molecular Architectures via o-Azaquinones We thank Dr. D. H. Huang, G. Siuzdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. This work was supported financially by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (P.S.B), and grants from ArrayBiopharma, Pfizer, Glaxo, Merck, Schering Plough, Hoffmann-La Roche, Boehringer Ingelheim, DuPont, and Abbott Laboratories. Angewandte Chemie (International Ed. in English). 40: 2145-2149. PMID 11433472 DOI: 10.1002/1521-3773(20010601)40:11<2145::AID-ANIE2145>3.0.CO;2-M |
0.552 |
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| 2001 |
Nicolaou KC, Mitchell HJ. Adventures in Carbohydrate Chemistry: New Synthetic Technologies, Chemical Synthesis, Molecular Design, and Chemical Biology A list of abbreviations can be found at the end of this article. Telemachos Charalambous was an inspiring teacher at the Pancyprian Gymnasium, Nicosia, Cyprus. Angewandte Chemie (International Ed. in English). 40: 1576-1624. PMID 11353467 DOI: 10.1002/1521-3773(20010504)40:9<1576::Aid-Anie15760>3.0.Co;2-G |
0.661 |
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| 2001 |
Nicolaou KC, Pihko PM, Diedrichs N, Zou N, Bernal F. Synthesis of the FGHI Ring System of Azaspiracid We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from Bristol-Myers Squibb (F.B.), postdoctoral fellowships from the Academy of Finland, the Ella and Georg Ehrnrooth Foundation, and the Tauno Tönning Foundation (all to P.M.P.), ArrayBiopharma (N.Z.), and Bayer AG (N.D.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 1573. PMID 11353466 DOI: 10.1002/1521-3773(20010504)40:9<1573::AID-ANIE15733>3.0.CO;2-D |
0.707 |
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| 2001 |
Nicolaou KC, Sugita K, Baran PS, Zhong YL. New Synthetic Technology for the Construction of N-Containing Quinones and Derivatives Thereof: Total Synthesis of Epoxyquinomycin B We thank Dr. D. H. Huang, Dr. G. Siuzdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (P.B.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 1573. PMID 11353465 DOI: 10.1002/1521-3773(20010504)40:9<1573::AID-ANIE15732>3.0.CO;2-G |
0.593 |
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| 2001 |
Nicolaou KC, Boddy CN. Behind enemy lines. Scientific American. 284: 54-61. PMID 11341163 DOI: 10.1038/Scientificamerican0501-54 |
0.557 |
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| 2001 |
Nicolaou KC, Pihko PM, Diedrichs N, Zou N, Bernal F. Synthesis of the FGHI Ring System of Azaspiracid We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from Bristol-Myers Squibb (F.B.), postdoctoral fellowships from the Academy of Finland, the Ella and Georg Ehrnrooth Foundation, and the Tauno Tönning Foundation (all to P.M.P.), ArrayBiopharma (N.Z.), and Bayer AG (N.D.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 1262-1265. PMID 11301444 DOI: 10.1002/1521-3773(20010401)40:7<1262::Aid-Anie1262>3.0.Co;2-9 |
0.747 |
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| 2001 |
Nicolaou KC, Boddy CN, Siegel JS. Does CIP Nomenclature Adequately Handle Molecules with Multiple Stereoelements? A Case Study of Vancomycin and Cognates We would like to thank Professor Dieter Hellwinkel for pointing out to us the stereochemical discrepancies in our review6 and elsewhere in the literature, and Kurt Mislow for stimulating and useful discussions. Angewandte Chemie (International Ed. in English). 40: 701-704. PMID 11241596 DOI: 10.1002/1521-3773(20010216)40:4<701::Aid-Anie7010>3.3.Co;2-F |
0.584 |
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| 2001 |
Nicolaou KC, Sugita K, Baran PS, Zhong YL. New Synthetic Technology for the Construction of N-Containing Quinones and Derivatives Thereof: Total Synthesis of Epoxyquinomycin B We thank Dr. D. H. Huang, Dr. G. Siuzdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (P.B.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 207-210. PMID 11169714 DOI: 10.1002/1521-3773(20010105)40:1<207::AID-ANIE207>3.0.CO;2-K |
0.593 |
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| 2001 |
Nicolaou KC, Baran PS, Kranich R, Zhong YL, Sugita K, Zou N. Mechanistic Studies of Periodinane-Mediated Reactions of Anilides and Related Systems Professors M. G. Finn, A. Eschenmoser, and M. E. Newcomb are gratefully acknowledged for valuable discussions and suggestions. We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. We would also like to thank Dr. G. Vasilikogiannakis for helpful discussions and an anonymous referee for critical suggestions. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (P.B.), postdoctoral fellowships from ArrayBiopharma (N.Z.) and Bayer AG (R.K.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 40: 202-206. PMID 11169713 DOI: 10.1002/1521-3773(20010105)40:1<202::AID-ANIE202>3.0.CO;2-3 |
0.552 |
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| 2001 |
Nicolaou KC, Safina BS, Winssinger NC. A New Photolabile Linker for the Photoactivation of Carboxyl Groups Synlett. 2001: 900-903. DOI: 10.1055/S-2001-14661 |
0.359 |
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| 2001 |
Pihko AJ, Nicolaou KC, Koskinen AMP. An expedient synthesis of D-callipeltose Tetrahedron Asymmetry. 12: 937-942. DOI: 10.1016/S0957-4166(01)00146-X |
0.34 |
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| 2001 |
Nicolaou KC, Sugita K, Baran PS, Zhong Y. ChemInform Abstract: New Synthetic Technology for the Construction of N-Containing Quinones and Derivatives Thereof: Total Synthesis of Epoxyquinomycin B. Cheminform. 32: no-no. DOI: 10.1002/chin.200115055 |
0.633 |
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| 2001 |
Nicolaou KC, Gray D, Tae J. Total synthesis of hamigerans: Part 2. Implementation of the intramolecular Diels - Alder trapping of photochemically generated hydroxy-o-quinodimethanes; strategy and completion of the synthesis Angewandte Chemie - International Edition. 40: 3679-3683. DOI: 10.1002/1521-3773(20011001)40:19<3679::AID-ANIE3679>3.0.CO;2-T |
0.551 |
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| 2001 |
Nicolaou KC, Gray D, Tae J. Total synthesis of hamigerans: Part 1. Development of synthetic technology for the construction of benzannulated polycyclic systems by the intramolecular trapping of photogenerated hydroxy-o-quinodimethanes and synthesis of key building blocks Angewandte Chemie - International Edition. 40: 3675-3678. DOI: 10.1002/1521-3773(20011001)40:19<3675::AID-ANIE3675>3.0.CO;2-G |
0.541 |
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| 2001 |
Nicolaou KC, Vega JA, Vassilikogiannakis G. cis-3,4-Dichlorocyclobutene as a Versatile Synthon in Organic Synthesis. Rapid Entry into Complex Polycyclic Systems with Remarkably Stereospecific Reactions Angewandte Chemie. 113: 4573-4577. DOI: 10.1002/1521-3757(20011203)113:23<4573::Aid-Ange4573>3.0.Co;2-C |
0.337 |
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| 2001 |
Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K. Totalsynthese von Apoptolidin - Teil 2: Verknüpfung der Schlüsselintermediate und Abschluss der Synthese Angewandte Chemie. 113: 3972-3976. DOI: 10.1002/1521-3757(20011015)113:20<3972::Aid-Ange3972>3.0.Co;2-Z |
0.694 |
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| 2001 |
Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Wei H, Weyershausen B. Totalsynthese von Apoptolidin - Teil 1: Retrosynthese und Aufbau von Schlüsselintermediaten Angewandte Chemie. 113: 3968-3972. DOI: 10.1002/1521-3757(20011015)113:20<3968::Aid-Ange3968>3.0.Co;2-1 |
0.633 |
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| 2001 |
Nicolaou KC, Gray D, Tae J. Totalsynthese der Hamigerane - Teil 2: Anwendung der intramolekularen Diels-Alder-Reaktion zum Abfangen photochemisch erzeugter Hydroxy-o-chinodimethane sowie Strategie und Abschluss der Synthese Angewandte Chemie. 113: 3791-3795. DOI: 10.1002/1521-3757(20011001)113:19<3791::Aid-Ange3791>3.0.Co;2-J |
0.511 |
|
| 2001 |
Nicolaou KC, Gray D, Tae J. Totalsynthese der Hamigerane - Teil 1: Entwicklung einer Synthesemethode für den Aufbau benzanellierter polycyclischer Systeme durch intramolekulares Abfangen von photochemisch erzeugten Hydroxy-o-chinodimethanen und Synthese von Schlüsselintermediaten Angewandte Chemie. 113: 3787-3790. DOI: 10.1002/1521-3757(20011001)113:19<3787::Aid-Ange3787>3.0.Co;2-M |
0.486 |
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| 2001 |
Nicolaou KC, Mitchell HJ. Abenteuer in der Kohlenhydratchemie: Synthesestrategien, Synthesemethoden, Moleküldesign und biologische Chemie Angewandte Chemie. 113: 1624-1672. DOI: 10.1002/1521-3757(20010504)113:9<1624::Aid-Ange16240>3.0.Co;2-N |
0.569 |
|
| 2000 |
Nicolaou KC, Hughes R, Cho SY, Winssinger N, Smethurst C, Labischinski H, Endermann R. Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria. Angewandte Chemie (International Ed. in English). 39: 3823-3828. PMID 29711708 DOI: 10.1002/1521-3773(20001103)39:21<3823::Aid-Anie3823>3.0.Co;2-3 |
0.674 |
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| 2000 |
Nicolaou KC, Pfefferkorn JA, Schuler F, Roecker AJ, Cao GQ, Casida JE. Combinatorial synthesis of novel and potent inhibitors of NADH:ubiquinone oxidoreductase Chemistry and Biology. 7: 979-992. PMID 11137820 DOI: 10.1016/S1074-5521(00)00047-8 |
0.774 |
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| 2000 |
Nicolaou KC, Snyder SA, Simonsen KB, Koumbis AE. Model Studies towards Diazonamide A: Synthesis of the Heterocyclic Core We thank Dr. D. H. Huang, Dr. G. Suizdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. We also thank Professor R. H. Grubbs for a generous gift of catalyst 30. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (S.A.S.), postdoctoral fellowships from the Alfred Benzons Foundation and the Danish Natural Science Research Council (K.B.S.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, GlaxoWellcome, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 39: 3473-3478. PMID 11091394 DOI: 10.1002/1521-3773(20001002)39:19<3473::AID-ANIE3473>3.0.CO;2-E |
0.588 |
|
| 2000 |
Nicolaou KC, Fylaktakidou KC, Mitchell HJ, van Delft FL, Rodríguez RM, Conley SR, Jin Z. Total synthesis of everninomicin 13,384-1--Part 4: explorations of methodology; stereocontrolled synthesis of 1,1'-disaccharides, 1,2-seleno migrations in carbohydrates, and solution- and solid-phase synthesis of 2-deoxy glycosides and orthoesters. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 3166-85. PMID 11002995 DOI: 10.1002/1521-3765(20000901)6:17<3166::Aid-Chem3166>3.0.Co;2-Z |
0.709 |
|
| 2000 |
Nicolaou KC, Mitchell HJ, Rodríguez RM, Fylaktakidou KC, Suzuki H, Conley SR. Total synthesis of everninomicin 13,384-1--Part 3: synthesis of the DE fragment and completion of the total synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 3149-65. PMID 11002994 DOI: 10.1002/1521-3765(20000901)6:17<3149::Aid-Chem3149>3.0.Co;2-L |
0.686 |
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| 2000 |
Nicolaou KC, Mitchell HJ, Fylaktakidou KC, Rodríguez RM, Suzuki H. Total synthesis of everninomicin 13,384-1--Part 2: synthesis of the FGHA2 fragment. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 3116-48. PMID 11002993 DOI: 10.1002/1521-3765(20000901)6:17<3116::Aid-Chem3116>3.0.Co;2-8 |
0.698 |
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| 2000 |
Nicolaou KC, Rodríguez RM, Mitchell HJ, Suzuki H, Fylaktakidou KC, Baudoin O, van Delft FL. Total synthesis of everninomicin 13,384-1--Part 1: retrosynthetic analysis and synthesis of the A1B(A)C fragment. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 3095-115. PMID 11002992 DOI: 10.1002/1521-3765(20000901)6:17<3095::Aid-Chem3095>3.0.Co;2-4 |
0.772 |
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| 2000 |
Nicolaou KC, Hepworth D, King NP, Finlay MR, Scarpelli R, Pereira MM, Bollbuck B, Bigot A, Werschkun B, Winssinger N. Total synthesis of 16-desmethylepothilone B, epothilone B10, epothilone F, and related side chain modified epothilone B analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 2783-800. PMID 10985727 DOI: 10.1002/1521-3765(20000804)6:15<2783::Aid-Chem2783>3.0.Co;2-B |
0.595 |
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| 2000 |
Nicolaou KC, Koumbis AE, Snyder SA, Simonsen KB. Novel Reactions Initiated by Titanocene Methylidenes: Deoxygenation of Sulfoxides, N-Oxides, and Selenoxides We thank Drs. D. H. Huang and G. Suizdak for NMR spectroscopic and mass spectroscopic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), fellowships from the National Science Foundation (S.A.S.) and the Alfred Benzons Foundation (K.B.S.), and grants from Abbott, Amgen, Boehringer-Ingelheim, GlaxoWellcome, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 39: 2529-2533. PMID 10941126 DOI: 10.1002/1521-3773(20000717)39:14<2529::Aid-Anie2529>3.0.Co;2-E |
0.62 |
|
| 2000 |
Nicolaou KC, Baran PS, Zhong YL, Vega JA. Novel IBX-Mediated Processes for the Synthesis of Amino Sugars and Libraries Thereof We thank Dr. D. H. Huang, Dr. G. Siuzdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively, and Prof. H. M. R. Hoffmann and Prof. A. Eschenmoser for helpful discussions. We also thank Dr. Maria-Rosa Rodriguez and Mr. Keith Wilcoxen of these laboratories for early intermediates leading to 9-12. This work was financially supported by the National Institutes of Health (USA), The Skaggs Institute for Chemical Biology, fellowships from the Ministerio de Educacion y Cultura, Spain (J.A.V.) and the National Science Foundation (P.S.B), and grants from Array Biopharma, Pfizer, GlaxoWellcome, Merck, Schering Plough, Hoffmann-LaRoche, Boehringer Ingelheim, DuPont, and Abbott Laboratories. Angewandte Chemie (International Ed. in English). 39: 2525-2529. PMID 10941125 DOI: 10.1002/1521-3773(20000717)39:14<2525::AID-ANIE2525>3.0.CO;2-1 |
0.576 |
|
| 2000 |
Nicolaou KC, Jung JK, Yoon WH, He Y, Zhong YL, Baran PS. The Absolute Configuration and Asymmetric Total Synthesis of the CP Molecules (CP-263,114 and CP-225,917, Phomoidrides B and A) We thank Drs. D. H. Huang, G. Siuzdak, and R. Chadha for assistance with NMR spectroscopy, mass spectrometry, and X-ray crystallography, respectively. This work was financially supported by the National Institutes of Health (USA), The Skaggs Institute for Chemical Biology, doctoral fellowships from the National Science Foundation (P.S.B.) and Boehringer Ingelheim (Y.H.), and grants from Array Biopharma, Boehringer Ingelheim, Schering Plough, Pfizer, Glaxo, Merck, Hoffmann-La Roche, DuPont, and Abbott Laboratories. Angewandte Chemie (International Ed. in English). 39: 1829-1832. PMID 10934377 DOI: 10.1002/(Sici)1521-3773(20000515)39:10<1829::Aid-Anie1829>3.0.Co;2-6 |
0.746 |
|
| 2000 |
Nicolaou KC, Vassilikogiannakis G, Kranich R, Baran PS, Zhong YL, Natarajan S. New Synthetic Technology for the Mild and Selective One-Carbon Homologation of Hindered Aldehydes in the Presence of Ketones. Organic Letters. 2: 1895-1898. PMID 10891185 DOI: 10.1021/Ol000102U |
0.665 |
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| 2000 |
Nicolaou KC, Snyder SA, Bigot A, Pfefferkorn JA. Solution and Solid-Phase Synthesis of Functionalized 3-Arylbenzofurans by a Novel Cyclofragmentation - Release Pathway Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), doctoral fellowships from the National Science Foundation (S.A.S.) and the Department of Defense (J.A.P.), and grants from Abbott, Amgen, Boehringer - Ingelheim, Glaxo, Hoffmann - La Roche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie (International Ed. in English). 39: 1093-1096. PMID 10760931 DOI: 10.1002/(Sici)1521-3773(20000317)39:6<1093::Aid-Anie1093>3.0.Co;2-S |
0.74 |
|
| 2000 |
Nicolaou KC, Mitchell HJ, Fylaktakidou KC, Suzuki H, Rodríguez RM. 1,2-Seleno Migrations in Carbohydrate Chemistry: Solution and Solid-Phase Synthesis of 2-Deoxy Glycosides, Orthoesters, and Allyl Orthoesters We thank Drs. D. H. Huang and G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. We gratefully thank Nicolas Winssinger for helpful discussions and preparation of the selenium bromide resin. This work was financially supported by the Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), postdoctoral fellowships from M.E.C., Spain (R.M.R., Fullbright), the Japan Society for the Promotion of Science (H.S.), the George Hewitt Foundation (K.C.F.), and grants from Schering Plough, Pfizer, Glaxo, Merck, Hoffmann - La Roche, DuPont, Abbott Laboratories, and Boehringer - Ingelheim. Angewandte Chemie (International Ed. in English). 39: 1089-1093. PMID 10760930 DOI: 10.1002/(Sici)1521-3773(20000317)39:6<1089::Aid-Anie1089>3.0.Co;2-V |
0.604 |
|
| 2000 |
Nicolaou KC, Winssinger N, Hughes R, Smethurst C, Cho SY. New Selenium-Based Safety-Catch Linkers: Solid-Phase Semisynthesis of Vancomycin We thank Drs. D. H. Huang and G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), The Skaggs Institute for Chemical Biology, a fellowship from the George Hewitt Foundation (N. W.), and grants from Schering Plough, Pfizer, Glaxo, Merck, Hoffmann-La Roche, DuPont, and Abbott Laboratories. Angewandte Chemie (International Ed. in English). 39: 1084-1088. PMID 10760929 DOI: 10.1002/(Sici)1521-3773(20000317)39:6<1084::Aid-Anie1084>3.0.Co;2-O |
0.686 |
|
| 2000 |
Nicolaou KC, Cao GQ, Pfefferkorn JA. Selenium-Based Solid-Phase Synthesis of Benzopyrans II: Applications to Combinatorial Synthesis of Medicinally Relevant Small Organic Molecules. Angewandte Chemie (International Ed. in English). 39: 739-743. PMID 10760853 DOI: 10.1002/(Sici)1521-3773(20000218)39:4<739::Aid-Anie739>3.0.Co;2-Z |
0.668 |
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| 2000 |
Nicolaou KC, Pfefferkorn JA, Cao GQ. Selenium-Based Solid-Phase Synthesis of Benzopyrans I: Applications to Combinatorial Synthesis of Natural Products. Angewandte Chemie (International Ed. in English). 39: 734-739. PMID 10760852 DOI: 10.1002/(Sici)1521-3757(20000218)112:4<750::Aid-Ange750>3.0.Co;2-J |
0.686 |
|
| 2000 |
Nicolaou KC, Zhong YL, Baran PS. New Synthetic Technology for the Rapid Construction of Novel Heterocycles-Part 2. The Reaction of IBX with Anilides and Related Compounds. Angewandte Chemie (International Ed. in English). 39: 625-628. PMID 10671279 DOI: 10.1002/(Sici)1521-3773(20000204)39:3<625::Aid-Anie625>3.0.Co;2-# |
0.673 |
|
| 2000 |
Nicolaou KC, Zhong YL, Baran PS. New Synthetic Technology for the Rapid Construction of Novel Heterocycles-Part 1: The Reaction of Dess - Martin Periodinane with Anilides and Related Compounds. Angewandte Chemie (International Ed. in English). 39: 622-625. PMID 10671278 DOI: 10.1002/(Sici)1521-3773(20000204)39:3<622::Aid-Anie622>3.0.Co;2-B |
0.673 |
|
| 2000 |
Nicolaou KC, Vourloumis D, Winssinger N, Baran PS. The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century. Angewandte Chemie (International Ed. in English). 39: 44-122. PMID 10649349 DOI: 10.1002/(Sici)1521-3773(20000103)39:1<44::Aid-Anie44>3.0.Co;2-L |
0.748 |
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| 2000 |
Xiao XY, Li R, Zhuang H, Ewing B, Karunaratne K, Lillig J, Brown R, Nicolaou KC. Solid-phase combinatorial synthesis using MicroKan reactors, Rf tagging, and directed sorting. Biotechnology and Bioengineering. 71: 44-50. PMID 10629535 DOI: 10.1002/(Sici)1097-0290(200024)71:1<44::Aid-Bit7>3.0.Co;2-J |
0.414 |
|
| 2000 |
Nicolaou KC, Li Y, Weyershausen B, Wei H. Synthesis of the macrocyclic core of apoptolidin Chemical Communications. 307-308. DOI: 10.1039/B000424N |
0.596 |
|
| 2000 |
Nicolaou KC, Roecker AJ, Pfefferkorn JA, Cao GQ. A novel strategy for the solid-phase synthesis of substituted indolines [12] Journal of the American Chemical Society. 122: 2966-2967. DOI: 10.1021/Ja994373F |
0.801 |
|
| 2000 |
Nicolaou KC, Murphy F, Barluenga S, Ohshima T, Wei H, Xu J, Gray DLF, Baudoin O. Total Synthesis of the Novel Immunosuppressant Sanglifehrin A Journal of the American Chemical Society. 122: 3830-3838. DOI: 10.1021/Ja994285V |
0.795 |
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