Lewis A. Chodosh - Publications

Affiliations: 
Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering, Radiology, Oncology

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tsao LC, Crosby EJ, Trotter TN, Agarwal P, Hwang BJ, Acharya C, Shuptrine CW, Wang T, Wei J, Yang X, Lei G, Liu CX, Rabiola CA, Chodosh LA, Muller WJ, et al. CD47 blockade augmentation of Trastuzumab antitumor efficacy dependent upon antibody-dependent-cellular-phagocytosis. Jci Insight. PMID 31689243 DOI: 10.1172/jci.insight.131882  0.32
2019 Ecker BL, Lee JY, Sterner CJ, Solomon AC, Pant DK, Shen F, Peraza J, Vaught L, Mahendra S, Belka GK, Pan TC, Schmitz KH, Chodosh LA. Impact of obesity on breast cancer recurrence and minimal residual disease. Breast Cancer Research : Bcr. 21: 41. PMID 30867005 DOI: 10.1186/s13058-018-1087-7  0.76
2018 Gattelli A, García Solá ME, Roloff TC, Cardiff RD, Kordon EC, Chodosh LA, Hynes NE. Chronic expression of wild-type Ret receptor in the mammary gland induces luminal tumors that are sensitive to Ret inhibition. Oncogene. PMID 29695833 DOI: 10.1038/s41388-018-0235-y  0.64
2017 Sreekumar A, Toneff MJ, Toh E, Roarty K, Creighton CJ, Belka GK, Lee DK, Xu J, Chodosh LA, Richards JS, Rosen JM. WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis. Developmental Cell. PMID 29103953 DOI: 10.1016/j.devcel.2017.10.007  0.76
2017 Maxwell KN, Soucier-Ernst D, Tahirovic E, Troxel AB, Clark C, Feldman M, Colameco C, Kakrecha B, Langer M, Lieberman D, Morrissette JJD, Paul MR, Pan TC, Yee S, Shih N, ... ... Chodosh LA, et al. Erratum to: Comparative clinical utility of tumor genomic testing and cell-free DNA in metastatic breast cancer. Breast Cancer Research and Treatment. PMID 28653249 DOI: 10.1007/s10549-017-4339-9  0.6
2017 Maxwell KN, Soucier-Ernst D, Tahirovic E, Troxel AB, Clark C, Feldman M, Colameco C, Kakrecha B, Langer M, Lieberman D, Morrissette JJD, Paul MR, Pan TC, Yee S, Shih N, ... ... Chodosh LA, et al. Comparative clinical utility of tumor genomic testing and cell-free DNA in metastatic breast cancer. Breast Cancer Research and Treatment. PMID 28500398 DOI: 10.1007/s10549-017-4257-x  0.6
2016 Yee SS, Lieberman DB, Blanchard T, Rader J, Zhao J, Troxel AB, DeSloover D, Fox AJ, Daber RD, Kakrecha B, Sukhadia S, Belka GK, DeMichele AM, Chodosh LA, Morrissette JJ, et al. A novel approach for next-generation sequencing of circulating tumor cells. Molecular Genetics & Genomic Medicine. 4: 395-406. PMID 27468416 DOI: 10.1002/mgg3.210  0.76
2016 Turpin J, Ling C, Crosby EJ, Hartman ZC, Simond AM, Chodosh LA, Rennhack JP, Andrechek ER, Ozcelik J, Hallett M, Mills GB, Cardiff RD, Gray JW, Griffith OL, Muller WJ. The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment. Oncogene. PMID 27157621 DOI: 10.1038/onc.2016.129  0.64
2015 Abravanel DL, Belka GK, Pan TC, Pant DK, Collins MA, Sterner CJ, Chodosh LA. Notch promotes recurrence of dormant tumor cells following HER2/neu-targeted therapy. The Journal of Clinical Investigation. 125: 2484-96. PMID 25961456 DOI: 10.1172/JCI74883  1
2014 Yeh ES, Vernon-Grey A, Martin H, Chodosh LA. Tetracycline-regulated mouse models of cancer. Cold Spring Harbor Protocols. 2014: pdb.top069823. PMID 25275112 DOI: 10.1101/pdb.top069823  1
2014 Alvarez JV, Belka GK, Pan TC, Chen CC, Blankemeyer E, Alavi A, Karp JS, Chodosh LA. Oncogene pathway activation in mammary tumors dictates FDG-PET uptake. Cancer Research. 74: 7583-98. PMID 25239452 DOI: 10.1158/0008-5472.CAN-14-1235  1
2014 Payne AW, Pant DK, Pan TC, Chodosh LA. Ceramide kinase promotes tumor cell survival and mammary tumor recurrence. Cancer Research. 74: 6352-63. PMID 25164007 DOI: 10.1158/0008-5472.CAN-14-1292  1
2014 Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, ... ... Chodosh LA, et al. Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metabolism. 20: 306-19. PMID 24998913 DOI: 10.1016/j.cmet.2014.06.004  1
2014 Feng Y, Pan TC, Pant DK, Chakrabarti KR, Alvarez JV, Ruth JR, Chodosh LA. SPSB1 promotes breast cancer recurrence by potentiating c-MET signaling. Cancer Discovery. 4: 790-803. PMID 24786206 DOI: 10.1158/2159-8290.CD-13-0548  1
2014 Searleman AC, Iliuk AB, Collier TS, Chodosh LA, Tao WA, Bose R. Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer. Electrophoresis. 35: 3463-9. PMID 24723360 DOI: 10.1002/elps.201400022  1
2013 Alvarez JV, Pan Tc, Ruth J, Feng Y, Zhou A, Pant D, Grimley JS, Wandless TJ, DeMichele A, Chodosh LA. Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy Cancer Cell. 24: 30-44. PMID 23770012 DOI: 10.1016/j.ccr.2013.05.007  1
2013 Bean GR, Ganesan YT, Dong Y, Takeda S, Liu H, Chan PM, Huang Y, Chodosh LA, Zambetti GP, Hsieh JJ, Cheng EH. PUMA and BIM are required for oncogene inactivation-induced apoptosis. Science Signaling. 6: ra20. PMID 23532334 DOI: 10.1126/scisignal.2003483  1
2013 Yeh ES, Belka GK, Vernon AE, Chen CC, Jung JJ, Chodosh LA. Hunk negatively regulates c-myc to promote Akt-mediated cell survival and mammary tumorigenesis induced by loss of Pten. Proceedings of the National Academy of Sciences of the United States of America. 110: 6103-8. PMID 23520049 DOI: 10.1073/pnas.1217415110  1
2013 Patterson RE, Colditz GA, Hu FB, Schmitz KH, Ahima RS, Brownson RC, Carson KR, Chavarro JE, Chodosh LA, Gehlert S, Gill J, Glanz K, Haire-Joshu D, Herbst KL, Hoehner CM, et al. The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design. Cancer Causes & Control : Ccc. 24: 695-704. PMID 23378138 DOI: 10.1007/s10552-013-0150-z  1
2013 Thiel AT, Feng Z, Pant DK, Chodosh LA, Hua X. The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia. Haematologica. 98: 918-27. PMID 23349306 DOI: 10.3324/haematol.2012.074195  1
2013 Magnitsky S, Belka GK, Sterner C, Pickup S, Chodosh LA, Glickson JD. Lactate detection in inducible and orthotopic Her2/neu mammary gland tumours in mouse models. Nmr in Biomedicine. 26: 35-42. PMID 22767445 DOI: 10.1002/nbm.2816  1
2012 Chen CC, Stairs DB, Boxer RB, Belka GK, Horseman ND, Alvarez JV, Chodosh LA. Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. Genes & Development. 26: 2154-68. PMID 23028142 DOI: 10.1101/gad.197343.112  1
2012 Chitnis NS, Pytel D, Bobrovnikova-Marjon E, Pant D, Zheng H, Maas NL, Frederick B, Kushner JA, Chodosh LA, Koumenis C, Fuchs SY, Diehl JA. miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. Molecular Cell. 48: 353-64. PMID 23022383 DOI: 10.1016/j.molcel.2012.08.025  1
2012 Qu W, Oya S, Lieberman BP, Ploessl K, Wang L, Wise DR, Divgi CR, Chodosh LA, Chodosh LP, Thompson CB, Kung HF. Preparation and characterization of L-[5-11C]-glutamine for metabolic imaging of tumors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 98-105. PMID 22173839 DOI: 10.2967/jnumed.111.093831  1
2012 Alvarez JV, Yeh ES, Feng Y, Chodosh LA. Oncogene addiction: Mouse models and clinical relevance for molecularly targeted therapies Genetically Engineered Mice For Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing. 527-547. DOI: 10.1007/978-0-387-69805-2_25  0.64
2011 Lieberman BP, Ploessl K, Wang L, Qu W, Zha Z, Wise DR, Chodosh LA, Belka G, Thompson CB, Kung HF. PET imaging of glutaminolysis in tumors by 18F-(2S,4R)4-fluoroglutamine. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 1947-55. PMID 22095958 DOI: 10.2967/jnumed.111.093815  1
2011 Chodosh LA. Breast cancer: current state and future promise. Breast Cancer Research : Bcr. 13: 113. PMID 22071145 DOI: 10.1186/bcr3045  1
2011 Zhang XY, Pfeiffer HK, Mellert HS, Stanek TJ, Sussman RT, Kumari A, Yu D, Rigoutsos I, Thomas-Tikhonenko A, Seidel HE, Chodosh LA, Packham G, Baserga R, McMahon SB. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC. Molecular and Cellular Biology. 31: 5037-45. PMID 21986497 DOI: 10.1128/MCB.06297-11  1
2011 Markosyan N, Chen EP, Ndong VN, Yao Y, Sterner CJ, Chodosh LA, Lawson JA, Fitzgerald GA, Smyth EM. Deletion of cyclooxygenase 2 in mouse mammary epithelial cells delays breast cancer onset through augmentation of type 1 immune responses in tumors. Carcinogenesis. 32: 1441-9. PMID 21771729 DOI: 10.1093/carcin/bgr134  1
2011 Yori JL, Seachrist DD, Johnson E, Lozada KL, Abdul-Karim FW, Chodosh LA, Schiemann WP, Keri RA. Krüppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer. Neoplasia (New York, N.Y.). 13: 601-10. PMID 21750654 DOI: 10.1593/neo.11260  1
2011 Whiteaker JR, Lin C, Kennedy J, Hou L, Trute M, Sokal I, Yan P, Schoenherr RM, Zhao L, Voytovich UJ, Kelly-Spratt KS, Krasnoselsky A, Gafken PR, Hogan JM, Jones LA, ... ... Chodosh LA, et al. A targeted proteomics-based pipeline for verification of biomarkers in plasma. Nature Biotechnology. 29: 625-34. PMID 21685906 DOI: 10.1038/nbt.1900  1
2011 Pitteri SJ, Kelly-Spratt KS, Gurley KE, Kennedy J, Buson TB, Chin A, Wang H, Zhang Q, Wong CH, Chodosh LA, Nelson PS, Hanash SM, Kemp CJ. Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression. Cancer Research. 71: 5090-100. PMID 21653680 DOI: 10.1158/0008-5472.CAN-11-0568  1
2011 Schoenherr RM, Kelly-Spratt KS, Lin C, Whiteaker JR, Liu T, Holzman T, Coleman I, Feng LC, Lorentzen TD, Krasnoselsky AL, Wang P, Liu Y, Gurley KE, Amon LM, Schepmoes AA, ... ... Chodosh LA, et al. Proteome and transcriptome profiles of a Her2/Neu-driven mouse model of breast cancer. Proteomics. Clinical Applications. 5: 179-88. PMID 21448875 DOI: 10.1002/prca.201000037  1
2011 Brown RL, Reinke LM, Damerow MS, Perez D, Chodosh LA, Yang J, Cheng C. CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. The Journal of Clinical Investigation. 121: 1064-74. PMID 21393860 DOI: 10.1172/JCI44540  1
2011 Yeh ES, Yang TW, Jung JJ, Gardner HP, Cardiff RD, Chodosh LA. Hunk is required for HER2/neu-induced mammary tumorigenesis. The Journal of Clinical Investigation. 121: 866-79. PMID 21393859 DOI: 10.1172/JCI42928  1
2011 Connelly L, Barham W, Onishko HM, Sherrill T, Chodosh LA, Blackwell TS, Yull FE. Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden Oncogene. 30: 1402-1412. PMID 21076466 DOI: 10.1038/onc.2010.521  1
2010 McHenry PR, Sears JC, Herrick MP, Chang P, Heckman-Stoddard BM, Rybarczyk M, Chodosh LA, Gunther EJ, Hilsenbeck SG, Rosen JM, Vargo-Gogola T. P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis. Breast Cancer Research : Bcr. 12: R73. PMID 20860838 DOI: 10.1186/bcr2643  1
2010 Chen CC, Boxer RB, Stairs DB, Portocarrero CP, Horton RH, Alvarez JV, Birnbaum MJ, Chodosh LA. Akt is required for Stat5 activation and mammary differentiation. Breast Cancer Research : Bcr. 12: R72. PMID 20849614 DOI: 10.1186/bcr2640  1
2010 Mazumdar J, Hickey MM, Pant DK, Durham AC, Sweet-Cordero A, Vachani A, Jacks T, Chodosh LA, Kissil JL, Simon MC, Keith B. HIF-2alpha deletion promotes Kras-driven lung tumor development. Proceedings of the National Academy of Sciences of the United States of America. 107: 14182-7. PMID 20660313 DOI: 10.1073/pnas.1001296107  1
2010 Zeng X, Shaikh FY, Harrison MK, Adon AM, Trimboli AJ, Carroll KA, Sharma N, Timmers C, Chodosh LA, Leone G, Saavedra HI. The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2 Oncogene. 29: 5103-5112. PMID 20581865 DOI: 10.1038/onc.2010.253  1
2010 Connelly L, Barham W, Pigg R, Saint-Jean L, Sherrill T, Cheng DS, Chodosh LA, Blackwell TS, Yull FE. Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection. Journal of Cellular Physiology. 222: 73-81. PMID 19746431 DOI: 10.1002/jcp.21922  1
2009 Castilho RM, Squarize CH, Chodosh LA, Williams BO, Gutkind JS. mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging. Cell Stem Cell. 5: 279-89. PMID 19733540 DOI: 10.1016/j.stem.2009.06.017  1
2009 McCoy EL, Iwanaga R, Jedlicka P, Abbey NS, Chodosh LA, Heichman KA, Welm AL, Ford HL. Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition. The Journal of Clinical Investigation. 119: 2663-77. PMID 19726883 DOI: 10.1172/JCI37691  1
2009 Wertheim GB, Yang TW, Pan TC, Ramne A, Liu Z, Gardner HP, Dugan KD, Kristel P, Kreike B, van de Vijver MJ, Cardiff RD, Reynolds C, Chodosh LA. The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis. Proceedings of the National Academy of Sciences of the United States of America. 106: 15855-60. PMID 19717424 DOI: 10.1073/pnas.0906993106  1
2009 Muraoka-Cook RS, Sandahl MA, Strunk KE, Miraglia LC, Husted C, Hunter DM, Elenius K, Chodosh LA, Earp HS. ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo. Molecular and Cellular Biology. 29: 4935-48. PMID 19596786 DOI: 10.1128/MCB.01705-08  1
2009 Fiore F, Estebe B, Gibier P, Orsoni JC, Courbard JR, Chodosh LA, Birnbaum D, Delapeyrière O. Abnormal mammary gland development in MMTV-CBLC transgenic mouse. In Vivo (Athens, Greece). 23: 225-8. PMID 19414407  1
2008 Shen Q, Uray IP, Li Y, Zhang Y, Hill J, Xu XC, Young MR, Gunther EJ, Hilsenbeck SG, Colburn NH, Chodosh LA, Brown PH. Targeting the activator protein 1 transcription factor for the prevention of estrogen receptor-negative mammary tumors. Cancer Prevention Research (Philadelphia, Pa.). 1: 45-55. PMID 19138935 DOI: 10.1158/1940-6207.CAPR-08-0034  1
2008 Liu Z, Wang M, Alvarez JV, Bonney ME, Chen CC, D'Cruz C, Pan TC, Tadesse MG, Chodosh LA. Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo. Genome Biology. 9: R180. PMID 19094238 DOI: 10.1186/gb-2008-9-12-r180  1
2008 Oakes SR, Naylor MJ, Asselin-Labat ML, Blazek KD, Gardiner-Garden M, Hilton HN, Kazlauskas M, Pritchard MA, Chodosh LA, Pfeffer PL, Lindeman GJ, Visvader JE, Ormandy CJ. The Ets transcription factor Elf5 specifies mammary alveolar cell fate. Genes & Development. 22: 581-6. PMID 18316476 DOI: 10.1101/gad.1614608  1
2008 Debies MT, Gestl SA, Mathers JL, Mikse OR, Leonard TL, Moody SE, Chodosh LA, Cardiff RD, Gunther EJ. Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss. The Journal of Clinical Investigation. 118: 51-63. PMID 18060046 DOI: 10.1172/JCI33320  1
2007 Whiteaker JR, Zhang H, Zhao L, Wang P, Kelly-Spratt KS, Ivey RG, Piening BD, Feng LC, Kasarda E, Gurley KE, Eng JK, Chodosh LA, Kemp CJ, McIntosh MW, Paulovich AG. Integrated pipeline for mass spectrometry-based discovery and confirmation of biomarkers demonstrated in a mouse model of breast cancer. Journal of Proteome Research. 6: 3962-75. PMID 17711321 DOI: 10.1021/pr070202v  1
2007 Vernon AE, Bakewell SJ, Chodosh LA. Deciphering the molecular basis of breast cancer metastasis with mouse models. Reviews in Endocrine & Metabolic Disorders. 8: 199-213. PMID 17657606 DOI: 10.1007/s11154-007-9041-5  1
2007 Cowling VH, D'Cruz CM, Chodosh LA, Cole MD. c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1. Molecular and Cellular Biology. 27: 5135-46. PMID 17485441 DOI: 10.1128/MCB.02282-06  1
2007 Sarkisian CJ, Keister BA, Stairs DB, Boxer RB, Moody SE, Chodosh LA. Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. Nature Cell Biology. 9: 493-505. PMID 17450133 DOI: 10.1038/ncb1567  1
2007 Jones RA, Campbell CI, Gunther EJ, Chodosh LA, Petrik JJ, Khokha R, Moorehead RA. Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation. Oncogene. 26: 1636-44. PMID 16953219 DOI: 10.1038/sj.onc.1209955  1
2006 Boxer RB, Stairs DB, Dugan KD, Notarfrancesco KL, Portocarrero CP, Keister BA, Belka GK, Cho H, Rathmell JC, Thompson CB, Birnbaum MJ, Chodosh LA. Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation. Cell Metabolism. 4: 475-90. PMID 17141631 DOI: 10.1016/j.cmet.2006.10.011  1
2006 Sutherland KD, Vaillant F, Alexander WS, Wintermantel TM, Forrest NC, Holroyd SL, McManus EJ, Schutz G, Watson CJ, Chodosh LA, Lindeman GJ, Visvader JE. c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3. The Embo Journal. 25: 5805-15. PMID 17139252 DOI: 10.1038/sj.emboj.7601455  1
2006 Alvarez JV, Perez D, Chodosh LA. mILC-ing the mouse mammary gland: A model for invasive lobular carcinoma. Cancer Cell. 10: 347-9. PMID 17097555 DOI: 10.1016/j.ccr.2006.10.016  1
2006 Chodosh LA, Cardiff RD. In vivo imaging of the mammary gland: the shape of things to come. Journal of Mammary Gland Biology and Neoplasia. 11: 101-2. PMID 17089204 DOI: 10.1007/s10911-006-9016-2  1
2006 Jang JW, Boxer RB, Chodosh LA. Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis. Molecular and Cellular Biology. 26: 8109-21. PMID 16908535 DOI: 10.1128/MCB.00404-06  1
2006 Wang M, Master SR, Chodosh LA. Computational expression deconvolution in a complex mammalian organ. Bmc Bioinformatics. 7: 328. PMID 16817968 DOI: 10.1186/1471-2105-7-328  1
2006 Hayworth CR, Moody SE, Chodosh LA, Krieg P, Rimer M, Thompson WJ. Induction of neuregulin signaling in mouse schwann cells in vivo mimics responses to denervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6873-84. PMID 16793894 DOI: 10.1523/JNEUROSCI.1086-06.2006  1
2006 Blakely CM, Stoddard AJ, Belka GK, Dugan KD, Notarfrancesco KL, Moody SE, D'Cruz CM, Chodosh LA. Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy. Cancer Research. 66: 6421-31. PMID 16778221 DOI: 10.1158/0008-5472.CAN-05-4235  1
2006 Shen Q, Zhang Y, Uray IP, Hill JL, Kim HT, Lu C, Young MR, Gunther EJ, Hilsenbeck SG, Chodosh LA, Colburn NH, Brown PH. The AP-1 transcription factor regulates postnatal mammary gland development. Developmental Biology. 295: 589-603. PMID 16678816 DOI: 10.1016/j.ydbio.2006.03.042  1
2006 Hu CJ, Iyer S, Sataur A, Covello KL, Chodosh LA, Simon MC. Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Molecular and Cellular Biology. 26: 3514-26. PMID 16611993 DOI: 10.1128/MCB.26.9.3514-3526.2006  1
2006 Wang X, Bo J, Bridges T, Dugan KD, Pan TC, Chodosh LA, Montell DJ. Analysis of cell migration using whole-genome expression profiling of migratory cells in the Drosophila ovary. Developmental Cell. 10: 483-95. PMID 16580993 DOI: 10.1016/j.devcel.2006.02.003  1
2006 Vargo-Gogola T, Heckman BM, Gunther EJ, Chodosh LA, Rosen JM. P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland. Molecular Endocrinology (Baltimore, Md.). 20: 1391-405. PMID 16469769 DOI: 10.1210/me.2005-0426  1
2006 Ponomareva ON, Ma H, Vock VM, Ellerton EL, Moody SE, Dakour R, Chodosh LA, Rimer M. Defective neuromuscular synaptogenesis in mice expressing constitutively active ErbB2 in skeletal muscle fibers. Molecular and Cellular Neurosciences. 31: 334-45. PMID 16278083 DOI: 10.1016/j.mcn.2005.10.004  1
2005 Stairs DB, Notarfrancesco KL, Chodosh LA. The serine/threonine kinase, Krct, affects endbud morphogenesis during murine mammary gland development. Transgenic Research. 14: 919-40. PMID 16315096 DOI: 10.1007/s11248-005-1806-6  1
2005 Moody SE, Perez D, Pan TC, Sarkisian CJ, Portocarrero CP, Sterner CJ, Notorfrancesco KL, Cardiff RD, Chodosh LA. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell. 8: 197-209. PMID 16169465 DOI: 10.1016/j.ccr.2005.07.009  1
2005 Huber LJ, Chodosh LA. Dynamics of DNA repair suggested by the subcellular localization of Brca1 and Brca2 proteins. Journal of Cellular Biochemistry. 96: 47-55. PMID 16052489 DOI: 10.1002/jcb.20517  1
2005 Frech MS, Halama ED, Tilli MT, Singh B, Gunther EJ, Chodosh LA, Flaws JA, Furth PA. Deregulated estrogen receptor alpha expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ. Cancer Research. 65: 681-5. PMID 15705859  1
2005 Master SR, Stoddard AJ, Bailey LC, Pan TC, Dugan KD, Chodosh LA. Genomic analysis of early murine mammary gland development using novel probe-level algorithms. Genome Biology. 6: R20. PMID 15693949 DOI: 10.1186/gb-2005-6-2-r20  1
2005 Blakely CM, Sintasath L, D'Cruz CM, Hahn KT, Dugan KD, Belka GK, Chodosh LA. Developmental stage determines the effects of MYC in the mammary epithelium. Development (Cambridge, England). 132: 1147-60. PMID 15689376 DOI: 10.1242/dev.01655  1
2004 Master SR, Chodosh LA. Large-scale transcriptional profiling of murine mammary development. Breast Disease. 19: 47-57. PMID 15687697  1
2004 Boxer RB, Jang JW, Sintasath L, Chodosh LA. Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation. Cancer Cell. 6: 577-86. PMID 15607962 DOI: 10.1016/j.ccr.2004.10.013  1
2004 Muraoka-Cook RS, Kurokawa H, Koh Y, Forbes JT, Roebuck LR, Barcellos-Hoff MH, Moody SE, Chodosh LA, Arteaga CL. Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors. Cancer Research. 64: 9002-11. PMID 15604265 DOI: 10.1158/0008-5472.CAN-04-2111  1
2004 Sgagias MK, Wagner KU, Hamik B, Stoeger S, Spieker R, Huber LJ, Chodosh LA, Cowan KH. Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS. Cell Cycle (Georgetown, Tex.). 3: 1451-6. PMID 15492509  1
2004 Kim SS, Cao L, Li C, Xu X, Huber LJ, Chodosh LA, Deng CX. Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1. Molecular and Cellular Biology. 24: 9498-507. PMID 15485917 DOI: 10.1128/MCB.24.21.9498-9507.2004  1
2004 Welch JJ, Watts JA, Vakoc CR, Yao Y, Wang H, Hardison RC, Blobel GA, Chodosh LA, Weiss MJ. Global regulation of erythroid gene expression by transcription factor GATA-1. Blood. 104: 3136-47. PMID 15297311 DOI: 10.1182/blood-2004-04-1603  1
2004 Wang JW, Gamsby JJ, Highfill SL, Mora LB, Bloom GC, Yeatman TJ, Pan TC, Ramne AL, Chodosh LA, Cress WD, Chen J, Kerr WG. Deregulated expression of LRBA facilitates cancer cell growth. Oncogene. 23: 4089-97. PMID 15064745 DOI: 10.1038/sj.onc.1207567  1
2004 Master SR, Chodosh LA. Evolving views of involution. Breast Cancer Research : Bcr. 6: 89-92. PMID 14979913 DOI: 10.1186/bcr765  1
2004 Xu H, Lee SJ, Suzuki E, Dugan KD, Stoddard A, Li HS, Chodosh LA, Montell C. A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. The Embo Journal. 23: 811-22. PMID 14963491 DOI: 10.1038/sj.emboj.7600112  1
2003 Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Molecular and Cellular Biology. 23: 9361-74. PMID 14645546 DOI: 10.1128/MCB.23.24.9361-9374.2003  1
2003 Sax JK, Stoddard A, Murphy ME, Chodosh L, El-Deiry WS. Microarray expression profiling of p53-dependent transcriptional changes in an immortalized mouse embryo fibroblast cell line. Cancer Biology & Therapy. 2: 416-30. PMID 14508116 DOI: 10.4161/cbt.2.4.477  1
2003 Fox CJ, Hammerman PS, Cinalli RM, Master SR, Chodosh LA, Thompson CB. The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. Genes & Development. 17: 1841-54. PMID 12869584 DOI: 10.1101/gad.1105003  1
2003 Rylski M, Welch JJ, Chen YY, Letting DL, Diehl JA, Chodosh LA, Blobel GA, Weiss MJ. GATA-1-mediated proliferation arrest during erythroid maturation. Molecular and Cellular Biology. 23: 5031-42. PMID 12832487 DOI: 10.1128/MCB.23.14.5031-5042.2003  1
2003 Chaudhry MA, Chodosh LA, McKenna WG, Muschel RJ. Gene expression profile of human cells irradiated in G1 and G2 phases of cell cycle. Cancer Letters. 195: 221-33. PMID 12767531 DOI: 10.1016/S0304-3835(03)00154-X  1
2003 Gunther EJ, Moody SE, Belka GK, Hahn KT, Innocent N, Dugan KD, Cardiff RD, Chodosh LA. Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. Genes & Development. 17: 488-501. PMID 12600942 DOI: 10.1101/gad.1051603  1
2003 Zhang Z, Liu Q, Luo Q, Zhang M, Blessington D, Zhou L, Chodosh LA, Zheng G, Chance B. 3D imaging of the metabolic state of c-MYC-induced mammary tumor with the cryo-imager Proceedings of Spie - the International Society For Optical Engineering. 4955: 647-655. DOI: 10.1117/12.503163  1
2002 Moody SE, Sarkisian CJ, Hahn KT, Gunther EJ, Pickup S, Dugan KD, Innocent N, Cardiff RD, Schnall MD, Chodosh LA. Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis. Cancer Cell. 2: 451-61. PMID 12498714 DOI: 10.1016/S1535-6108(02)00212-X  1
2002 Carmody RJ, Hilliard B, Maguschak K, Chodosh LA, Chen YH. Genomic scale profiling of autoimmune inflammation in the central nervous system: the nervous response to inflammation. Journal of Neuroimmunology. 133: 95-107. PMID 12446012 DOI: 10.1016/S0165-5728(02)00366-1  1
2002 D'Cruz CM, Moody SE, Master SR, Hartman JL, Keiper EA, Imielinski MB, Cox JD, Wang JY, Ha SI, Keister BA, Chodosh LA. Persistent parity-induced changes in growth factors, TGF-beta3, and differentiation in the rodent mammary gland. Molecular Endocrinology (Baltimore, Md.). 16: 2034-51. PMID 12198241 DOI: 10.1210/me.2002-0073  1
2002 Li C, Fox CJ, Master SR, Bindokas VP, Chodosh LA, Thompson CB. Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors. Proceedings of the National Academy of Sciences of the United States of America. 99: 9830-5. PMID 12118121 DOI: 10.1073/pnas.152571899  1
2002 Chodosh LA. The reciprocal dance between cancer and development. The New England Journal of Medicine. 347: 134-6. PMID 12110743 DOI: 10.1056/NEJMcibr020712  1
2002 Mullen AC, Hutchins AS, High FA, Lee HW, Sykes KJ, Chodosh LA, Reiner SL. Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nature Immunology. 3: 652-8. PMID 12055627 DOI: 10.1038/ni807  1
2002 Master SR, Hartman JL, D'Cruz CM, Moody SE, Keiper EA, Ha SI, Cox JD, Belka GK, Chodosh LA. Functional microarray analysis of mammary organogenesis reveals a developmental role in adaptive thermogenesis. Molecular Endocrinology (Baltimore, Md.). 16: 1185-203. PMID 12040007 DOI: 10.1210/mend.16.6.0865  1
2002 Chaudhry MA, Chodosh LA, McKenna WG, Muschel RJ. Gene expression profiling of HeLa cells in G1 or G2 phases. Oncogene. 21: 1934-42. PMID 11896627 DOI: 10.1038/sj.onc.1205264  1
2002 Gunther EJ, Belka GK, Wertheim GB, Wang J, Hartman JL, Boxer RB, Chodosh LA. A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 283-92. PMID 11874978 DOI: 10.1096/fj.01-0551com  1
2002 Wysolmerski JJ, Chodosh LA. Endocrine influences on mammary development and breast cancer risk Journal of Mammary Gland Biology and Neoplasia. 7: 1-2. DOI: 10.1023/A:1015742821350  1
2001 Buratowski S, Chodosh LA. Mobility shift DNA-binding assay using gel electrophoresis. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit6.8. PMID 21959763 DOI: 10.1002/0471141755.ph0608s13  1
2001 Chodosh LA, Buratowski S. Purification of DNA-binding proteins using biotin/streptavidin affinity systems. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 9.7. PMID 18429216 DOI: 10.1002/0471140864.ps0907s12  1
2001 Chodosh LA. Purification of DNA-binding proteins using biotin/streptavidin affinity systems Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. PMID 18265089  1
2001 Chodosh LA. UV crosslinking of proteins to nucleic acids Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. PMID 18265088  1
2001 Buratowski S, Chodosh LA. Mobility shift DNA-binding assay using gel electrophoresis. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 12.2. PMID 18265085 DOI: 10.1002/0471142727.mb1202s36  1
2001 Unger MA, Rishi M, Clemmer VB, Hartman JL, Keiper EA, Greshock JD, Chodosh LA, Liebman MN, Weber BL. Characterization of adjacent breast tumors using oligonucleotide microarrays Breast Cancer Research. 3: 336-341. PMID 11597324 DOI: 10.1186/bcr317  1
2001 Sarkisian CJ, Master SR, Huber LJ, Ha SI, Chodosh LA. Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals. The Journal of Biological Chemistry. 276: 37640-8. PMID 11477095 DOI: 10.1074/jbc.M106281200  1
2001 Huber LJ, Yang TW, Sarkisian CJ, Master SR, Deng CX, Chodosh LA. Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci. Molecular and Cellular Biology. 21: 4005-15. PMID 11359908 DOI: 10.1128/MCB.21.12.4005-4015.2001  1
2001 D'Cruz CM, Gunther EJ, Boxer RB, Hartman JL, Sintasath L, Moody SE, Cox JD, Ha SI, Belka GK, Golant A, Cardiff RD, Chodosh LA. c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nature Medicine. 7: 235-9. PMID 11175856 DOI: 10.1038/84691  1
2000 Gardner HP, Ha SI, Reynolds C, Chodosh LA. The caM kinase, Pnck, is spatially and temporally regulated during murine mammary gland development and may identify an epithelial cell subtype involved in breast cancer. Cancer Research. 60: 5571-7. PMID 11034105  1
2000 Gardner HP, Belka GK, Wertheim GB, Hartman JL, Ha SI, Gimotty PA, Marquis ST, Chodosh LA. Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland. Development (Cambridge, England). 127: 4493-509. PMID 11003847  1
2000 Chodosh LA, Gardner HP, Rajan JV, Stairs DB, Marquis ST, Leder PA. Protein kinase expression during murine mammary development. Developmental Biology. 219: 259-76. PMID 10694421 DOI: 10.1006/dbio.2000.9614  1
2000 Gardner HP, Rajan JV, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Marquis ST, Chodosh LA. Cloning, characterization, and chromosomal localization of Pnck, a Ca(2+)/calmodulin-dependent protein kinase. Genomics. 63: 279-88. PMID 10673339 DOI: 10.1006/geno.1999.6091  1
2000 Gardner HP, Wertheim GB, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Marquis ST, Chodosh LA. Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase. Genomics. 63: 46-59. PMID 10662544 DOI: 10.1006/geno.1999.6078  1
1999 Chodosh LA, D'Cruz CM, Gardner HP, Ha SI, Marquis ST, Rajan JV, Stairs DB, Wang JY, Wang M. Mammary gland development, reproductive history, and breast cancer risk. Cancer Research. 59: 1765-1771s; discussi. PMID 10197594  1
1998 Chodosh LA. Expression of BRCA1 and BRCA2 in Normal and Neoplastic Cells Journal of Mammary Gland Biology and Neoplasia. 3: 389-402. PMID 10819533  1
1998 Stairs DB, Perry Gardner H, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Chodosh LA. Cloning and characterization of Krct, a member of a novel subfamily of serine/threonine kinases. Human Molecular Genetics. 7: 2157-66. PMID 9817935  1
1998 Jensen DE, Proctor M, Marquis ST, Gardner HP, Ha SI, Chodosh LA, Ishov AM, Tommerup N, Vissing H, Sekido Y, Minna J, Borodovsky A, Schultz DC, Wilkinson KD, Maul GG, et al. BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. Oncogene. 16: 1097-112. PMID 9528852  1
1997 Radice GL, Ferreira-Cornwell MC, Robinson SD, Rayburn H, Chodosh LA, Takeichi M, Hynes RO. Precocious mammary gland development in P-cadherin-deficient mice. The Journal of Cell Biology. 139: 1025-32. PMID 9362520 DOI: 10.1083/jcb.139.4.1025  1
1997 Rajan JV, Marquis ST, Gardner HP, Chodosh LA. Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues. Developmental Biology. 184: 385-401. PMID 9133444 DOI: 10.1006/dbio.1997.8526  1
1997 Deckard-Janatpour K, Muller WJ, Chodosh LA, Gardner HP, Marquis ST, Coffey R, Cardiff RD. Differential expression of the neu transgene in murine mammary tissues International Journal of Oncology. 11: 235-241.  1
1996 Rajan JV, Wang M, Marquis ST, Chodosh LA. Brca2 is coordinately regulated with Brcal during proliferation and differentiation in mammary epithelial cells Proceedings of the National Academy of Sciences of the United States of America. 93: 13078-13083. PMID 8917547  1
1995 Marquis ST, Rajan JV, Wynshaw-Boris A, Xu J, Yin GY, Abel KJ, Weber BL, Chodosh LA. The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues Nature Genetics. 11: 17-26. PMID 7550308 DOI: 10.1038/ng0995-17  1
1993 Chodosh LA, Daniels GH. Addison’s disease Endocrinologist. 3: 166-181.  1
1989 Chodosh LA, Fire A, Samuels M, Sharp PA. 5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole inhibits transcription elongation by RNA polymerase II in vitro Journal of Biological Chemistry. 264: 2250-2257. PMID 2914905  1
1989 Chodosh LA, Buratowski S, Sharp PA. A yeast protein possesses the DNA-binding properties of the adenovirus major late transcription factor. Molecular and Cellular Biology. 9: 820-2. PMID 2651905  1
1988 Chodosh LA, Baldwin AS, Carthew RW, Sharp PA. Human CCAAT-binding proteins have heterologous subunits. Cell. 53: 11-24. PMID 3349524 DOI: 10.1016/0092-8674(88)90483-7  1
1988 Chodosh LA, Olesen J, Hahn S, Baldwin AS, Guarente L, Sharp PA. A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable. Cell. 53: 25-35. PMID 3280141 DOI: 10.1016/0092-8674(88)90484-9  1
1988 Morgan JG, Courtois G, Fourel G, Chodosh LA, Campbell L, Evans E, Crabtree GR. Sp1, a CAAT-binding factor, and the adenovirus major late promoter transcription factor interact with functional regions of the gamma-fibrinogen promoter Molecular and Cellular Biology. 8: 2628-2637. PMID 3043186  1
1987 Chodosh LA, Carthew RW, Morgan JG, Crabtree GR, Sharp PA. The adenovirus major late transcription factor activates the rat gamma-fibrinogen promoter. Science (New York, N.Y.). 238: 684-8. PMID 3672119  1
1987 Carthew RW, Chodosh LA, Sharp PA. The major late transcription factor binds to and activates the mouse metallothionein I promoter. Genes & Development. 1: 973-80. PMID 3428603  1
1986 Chodosh LA, Carthew RW, Sharp PA. A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Molecular and Cellular Biology. 6: 4723-33. PMID 3796614  1
1985 Carthew RW, Chodosh LA, Sharp PA. An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell. 43: 439-48. PMID 4075400 DOI: 10.1016/0092-8674(85)90174-6  1
1982 Smith BL, Anisowicz A, Chodosh LA, Sager R. DNA transfer of focus- and tumor-forming ability into nontumorigenic CHEF cells Proceedings of the National Academy of Sciences of the United States of America. 79: 1964-1968. PMID 6952247  1
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