| Year |
Citation |
Score |
| 2021 |
Chen K, Guo L, Wu C. How signaling pathways link extracellular mechano-environment to proline biosynthesis: A hypothesis: PINCH-1 and kindlin-2 sense mechanical signals from extracellular matrix and link them to proline biosynthesis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2100116. PMID 34218442 DOI: 10.1002/bies.202100116 |
0.302 |
|
| 2020 |
Wang M, Liu J, Tu Y, Zhao Z, Qu J, Chen K, Chen Y, Sun Y, Zhao H, Deng Y, Wu C. RSU-1 interaction with prohibitin-2 links cell-extracellular matrix detachment to downregulation of ERK signaling. The Journal of Biological Chemistry. 296: 100109. PMID 33853759 DOI: 10.1074/jbc.RA120.014413 |
0.39 |
|
| 2020 |
Liu J, Liu Z, Chen K, Chen W, Fang X, Li M, Zhou X, Ding N, Lei H, Guo C, Qian T, Wang Y, Liu L, Chen Y, Zhao H, ... ... Wu C, et al. Kindlin-2 promotes rear focal adhesion disassembly and directional persistence in cell migration. Journal of Cell Science. PMID 33277381 DOI: 10.1242/jcs.244616 |
0.305 |
|
| 2020 |
Wang M, Liu J, Tu Y, Zhao Z, Qu J, Chen K, Chen Y, Sun Y, Zhao H, Deng Y, Wu C. RSU-1 interaction with prohibitin-2 links cell-extracellular matrix detachment to down-regulation of extracellular signal-regulated kinase signalling. The Journal of Biological Chemistry. PMID 33229436 DOI: 10.1074/jbc.RA120.014413 |
0.397 |
|
| 2020 |
Zhu K, Lai Y, Cao H, Bai X, Liu C, Yan Q, Ma L, Chen D, Kanaporis G, Wang J, Li L, Cheng T, Wang Y, Wu C, Xiao G. Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice. Nature Communications. 11: 484. PMID 31980627 DOI: 10.1038/S41467-019-14186-Y |
0.321 |
|
| 2020 |
Cao H, Yan Q, Wang D, Lai Y, Zhou B, Zhang Q, Jin W, Lin S, Lei Y, Ma L, Guo Y, Wang Y, Wang Y, Bai X, Liu C, ... ... Wu C, et al. Focal adhesion protein Kindlin-2 regulates bone homeostasis in mice. Bone Research. 8: 2. PMID 31934494 DOI: 10.1038/S41413-019-0073-8 |
0.313 |
|
| 2019 |
Qian T, Liu C, Ding Y, Guo C, Cai R, Wang X, Wang R, Zhang K, Zhou L, Deng Y, Wu C, Sun Y. PINCH-1 interacts with myoferlin to promote breast cancer progression and metastasis. Oncogene. PMID 31801973 DOI: 10.1038/S41388-019-1135-5 |
0.326 |
|
| 2019 |
Wang Y, Yan Q, Zhao Y, Liu X, Lin S, Zhang P, Ma L, Lai Y, Bai X, Liu C, Wu C, Feng JQ, Chen D, Cao H, Xiao G. Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice. Jci Insight. 4. PMID 31723057 DOI: 10.1172/Jci.Insight.131692 |
0.325 |
|
| 2019 |
Guo L, Wang R, Zhang K, Yuan J, Wang J, Wang X, Ma J, Wu C. A PINCH-1-Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation. The Journal of Cell Biology. PMID 31578224 DOI: 10.1083/Jcb.201902022 |
0.379 |
|
| 2019 |
Guo L, Wang X, Yuan J, Zhu M, Fu X, Xu RH, Wu C, Wu Y. TSA restores hair follicle-inductive capacity of skin-derived precursors. Scientific Reports. 9: 2867. PMID 30814580 DOI: 10.1038/S41598-019-39394-W |
0.339 |
|
| 2019 |
Sun Y, Ding Y, Guo C, Liu C, Ma P, Ma S, Wang Z, Liu J, Qian T, Ma L, Deng Y, Wu C. α-Parvin promotes breast cancer progression and metastasis through interaction with G3BP2 and regulation of TWIST1 signaling. Oncogene. PMID 30804457 DOI: 10.1038/S41388-019-0762-1 |
0.333 |
|
| 2019 |
Guo L, Cui C, Zhang K, Wang J, Wang Y, Lu Y, Chen K, Yuan J, Xiao G, Tang B, Sun Y, Wu C. Kindlin-2 links mechano-environment to proline synthesis and tumor growth. Nature Communications. 10: 845. PMID 30783087 DOI: 10.1038/S41467-019-08772-3 |
0.345 |
|
| 2018 |
Guo L, Cai T, Chen K, Wang R, Wang J, Cui C, Yuan J, Zhang K, Liu Z, Deng Y, Xiao G, Wu C. Kindlin-2 regulates mesenchymal stem cell differentiation through control of YAP1/TAZ. The Journal of Cell Biology. PMID 29496737 DOI: 10.1083/Jcb.201612177 |
0.4 |
|
| 2017 |
Duan B, Ye D, Zhu S, Jia W, Lu C, Wang G, Guo X, Yu Y, Wu C, Kang J. HDAC10 promotes angiogenesis in endothelial cells through the PTPN22/ERK axis. Oncotarget. 8: 61338-61349. PMID 28977867 DOI: 10.18632/Oncotarget.18130 |
0.401 |
|
| 2017 |
Sun Y, Guo C, Ma P, Lai Y, Yang F, Cai J, Cheng Z, Zhang K, Liu Z, Tian Y, Sheng Y, Tian R, Deng Y, Xiao G, Wu C. Kindlin-2 Association with Rho GDP-Dissociation Inhibitor α Suppresses Rac1 Activation and Podocyte Injury. Journal of the American Society of Nephrology : Jasn. PMID 28775002 DOI: 10.1681/Asn.2016091021 |
0.414 |
|
| 2017 |
Li H, Deng Y, Sun K, Yang H, Liu J, Wang M, Zhang Z, Lin J, Wu C, Wei Z, Yu C. Structural basis of kindlin-mediated integrin recognition and activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739949 DOI: 10.1073/Pnas.1703064114 |
0.431 |
|
| 2016 |
Ou Y, Zhao Z, Zhang W, Wu Q, Wu C, Liu X, Fu M, Ji N, Wang D, Qiu J, Zhang L, Yu C, Song Y, Zhan Q. Kindlin-2 interacts with β-catenin and YB-1 to enhance EGFR transcription during glioma progression. Oncotarget. PMID 27713156 DOI: 10.18632/Oncotarget.12439 |
0.423 |
|
| 2016 |
Huang T, Liu R, Fu X, Yao D, Yang M, Liu Q, Lu WW, Wu C, Guan M. Aging reduces an ERRalpha-directed mitochondrial glutaminase expression suppressing glutamine anaplerosis and osteogenic differentiation of mesenchymal stem cells. Stem Cells (Dayton, Ohio). PMID 27501743 DOI: 10.1002/Stem.2470 |
0.323 |
|
| 2016 |
Wu C, You J, Fu J, Wang X, Zhang Y. PI3K/Akt mediates integrin signaling to control RNA polymerase I transcription. Molecular and Cellular Biology. PMID 26976639 DOI: 10.1128/Mcb.00004-16 |
0.313 |
|
| 2016 |
Kim SY, Hong SH, Basse PH, Wu C, Bartlett DL, Kwon YT, Lee YJ. Cancer Stem Cells Protect Non-Stem Cells from Anoikis: Bystander Effects. Journal of Cellular Biochemistry. PMID 26918647 DOI: 10.1002/Jcb.25527 |
0.385 |
|
| 2015 |
Cui XB, Li S, Li TT, Peng H, Jin TT, Zhang SM, Liu CX, Yang L, Shen YY, Li SG, Li N, Li Y, Hu JM, Jiang JF, Suo J, ... ... Wu CY, et al. Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma. Oncotarget. PMID 26657507 DOI: 10.18632/Oncotarget.6499 |
0.313 |
|
| 2015 |
Cui XB, Shen YY, Jin TT, Li S, Li TT, Zhang SM, Peng H, Liu CX, Li SG, Yang L, Li N, Hu JM, Jiang JF, Li M, Liang WH, ... ... Wu CY, et al. SLC39A6: a potential target for diagnosis and therapy of esophageal carcinoma. Journal of Translational Medicine. 13: 321. PMID 26444413 DOI: 10.1186/S12967-015-0681-Z |
0.374 |
|
| 2015 |
Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, et al. Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis. Nature Communications. 6: 7531. PMID 26151572 DOI: 10.1038/Ncomms8531 |
0.448 |
|
| 2015 |
Liu Z, Zhan Y, Tu Y, Chen K, Wu C. PDZ and LIM domain protein 1(PDLIM1)/CLP36 promotes breast cancer cell migration, invasion and metastasis through interaction with α-actinin Oncogene. 34: 1300-1311. PMID 24662836 DOI: 10.1038/Onc.2014.64 |
0.369 |
|
| 2014 |
Qian J, Yao B, Wu C. Fluorescence resonance energy transfer detection methods: Sensitized emission and acceptor bleaching. Experimental and Therapeutic Medicine. 8: 1375-1380. PMID 25289026 DOI: 10.3892/Etm.2014.1928 |
0.3 |
|
| 2014 |
Qu H, Tu Y, Guan JL, Xiao G, Wu C. Kindlin-2 tyrosine phosphorylation and interaction with Src serve as a regulatable switch in the integrin outside-in signaling circuit. The Journal of Biological Chemistry. 289: 31001-13. PMID 25237194 DOI: 10.1074/Jbc.M114.580811 |
0.479 |
|
| 2014 |
Ou YW, Zhao ZT, Wu CY, Xu BN, Song YM, Zhan QM. Mig-2 attenuates cisplatin-induced apoptosis of human glioma cells in vitro through AKT/JNK and AKT/p38 signaling pathways. Acta Pharmacologica Sinica. 35: 1199-206. PMID 25152024 DOI: 10.1038/Aps.2014.60 |
0.429 |
|
| 2013 |
Donthamsetty S, Bhave VS, Mars WM, Bowen WC, Orr A, Haynes MM, Wu C, Michalopoulos GK. Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis. Plos One. 8: e74625. PMID 24058607 DOI: 10.1371/Journal.Pone.0074625 |
0.345 |
|
| 2013 |
Teräväinen TP, Myllymäki SM, Friedrichs J, Strohmeyer N, Moyano JV, Wu C, Matlin KS, Muller DJ, Manninen A. αV-integrins are required for mechanotransduction in MDCK epithelial cells. Plos One. 8: e71485. PMID 23977051 DOI: 10.1371/Journal.Pone.0071485 |
0.491 |
|
| 2013 |
Song C, Zhu S, Wu C, Kang J. Histone deacetylase (HDAC) 10 suppresses cervical cancer metastasis through inhibition of matrix metalloproteinase (MMP) 2 and 9 expression. The Journal of Biological Chemistry. 288: 28021-33. PMID 23897811 DOI: 10.1074/Jbc.M113.498758 |
0.353 |
|
| 2013 |
Gkretsi V, Papanikolaou V, Zacharia LC, Athanassiou E, Wu C, Tsezou A. Mitogen-inducible Gene-2 (MIG2) and migfilin expression is reduced in samples of human breast cancer. Anticancer Research. 33: 1977-81. PMID 23645746 |
0.364 |
|
| 2013 |
Gkretsi V, Papanikolaou V, Dubos S, Papathanasiou I, Giotopoulou N, Valiakou V, Wu C, Malizos KN, Tsezou A. Migfilin's elimination from osteoarthritic chondrocytes further promotes the osteoarthritic phenotype via β-catenin upregulation. Biochemical and Biophysical Research Communications. 430: 494-9. PMID 23237804 DOI: 10.1016/J.Bbrc.2012.12.008 |
0.398 |
|
| 2013 |
Davidson B, Holth A, Nguyen MT, Tropé CG, Wu C. Migfilin, α-parvin and β-parvin are differentially expressed in ovarian serous carcinoma effusions, primary tumors and solid metastases. Gynecologic Oncology. 128: 364-70. PMID 23099104 DOI: 10.1016/J.Ygyno.2012.10.015 |
0.308 |
|
| 2012 |
Fan J, Ou YW, Wu CY, Yu CJ, Song YM, Zhan QM. Migfilin sensitizes cisplatin-induced apoptosis in human glioma cells in vitro. Acta Pharmacologica Sinica. 33: 1301-10. PMID 22983390 DOI: 10.1038/Aps.2012.123 |
0.434 |
|
| 2012 |
Ou Y, Ma L, Dong L, Ma L, Zhao Z, Ma L, Zhou W, Fan J, Wu C, Yu C, Zhan Q, Song Y. Migfilin protein promotes migration and invasion in human glioma through epidermal growth factor receptor-mediated phospholipase C-γ and STAT3 protein signaling pathways. The Journal of Biological Chemistry. 287: 32394-405. PMID 22843679 DOI: 10.1074/Jbc.M112.393900 |
0.398 |
|
| 2012 |
Qin J, Wu C. ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling. Current Opinion in Cell Biology. 24: 607-13. PMID 22763012 DOI: 10.1016/J.Ceb.2012.06.003 |
0.489 |
|
| 2012 |
Xiao G, Cheng H, Cao H, Chen K, Tu Y, Yu S, Jiao H, Yang S, Im HJ, Chen D, Chen J, Wu C. Critical role of filamin-binding LIM protein 1 (FBLP-1)/migfilin in regulation of bone remodeling. The Journal of Biological Chemistry. 287: 21450-60. PMID 22556421 DOI: 10.1074/Jbc.M111.331249 |
0.386 |
|
| 2012 |
He H, Ding F, Li Y, Luo A, Chen H, Wu C, Liu Z. Migfilin regulates esophageal cancer cell motility through promoting GSK-3β-mediated degradation of β-catenin. Molecular Cancer Research : McR. 10: 273-81. PMID 22246236 DOI: 10.1158/1541-7786.Mcr-11-0419 |
0.358 |
|
| 2011 |
Bavagnoli L, Dundon WG, Garbelli A, Zecchin B, Milani A, Parakkal G, Baldanti F, Paolucci S, Volmer R, Tu Y, Wu C, Capua I, Maga G. The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection. Plos One. 6: e27789. PMID 22110760 DOI: 10.1371/Journal.Pone.0027789 |
0.368 |
|
| 2011 |
Donthamsetty S, Mars WM, Orr A, Wu C, Michalopoulos GK. Protection against Fas-induced fulminant hepatic failure in liver specific integrin linked kinase knockout mice. Comparative Hepatology. 10: 11. PMID 22104495 DOI: 10.1186/1476-5926-10-11 |
0.325 |
|
| 2011 |
Liu J, Fukuda K, Xu Z, Ma YQ, Hirbawi J, Mao X, Wu C, Plow EF, Qin J. Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. The Journal of Biological Chemistry. 286: 43334-42. PMID 22030399 DOI: 10.1074/Jbc.M111.295352 |
0.365 |
|
| 2011 |
Wang D, Li Y, Wu C, Liu Y. PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression. Plos One. 6: e17048. PMID 21390327 DOI: 10.1371/Journal.Pone.0017048 |
0.441 |
|
| 2011 |
Qu H, Tu Y, Shi X, Larjava H, Saleem MA, Shattil SJ, Fukuda K, Qin J, Kretzler M, Wu C. Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins. Journal of Cell Science. 124: 879-91. PMID 21325030 DOI: 10.1242/Jcs.076976 |
0.444 |
|
| 2011 |
Donthamsetty S, Bhave VS, Kliment CS, Bowen WC, Mars WM, Bell AW, Stewart RE, Orr A, Wu C, Michalopoulos GK. Excessive hepatomegaly of mice with hepatocyte-targeted elimination of integrin linked kinase following treatment with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene. Hepatology (Baltimore, Md.). 53: 587-95. PMID 21274879 DOI: 10.1002/Hep.24040 |
0.306 |
|
| 2011 |
Yuan Y, Dong HP, Nymoen DA, Nesland JM, Wu C, Davidson B. PINCH-2 expression in cancers involving serosal effusions using quantitative PCR. Cytopathology. 22: 22-29. PMID 20500520 DOI: 10.1111/J.1365-2303.2010.00757.X |
0.321 |
|
| 2010 |
Bledzka K, Bialkowska K, Nie H, Qin J, Byzova T, Wu C, Plow EF, Ma YQ. Tyrosine phosphorylation of integrin beta3 regulates kindlin-2 binding and integrin activation. The Journal of Biological Chemistry. 285: 30370-4. PMID 20702409 DOI: 10.1074/Jbc.C110.134247 |
0.366 |
|
| 2010 |
Perera PM, Wypasek E, Madhavan S, Rath-Deschner B, Liu J, Nam J, Rath B, Huang Y, Deschner J, Piesco N, Wu C, Agarwal S. Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes. Arthritis Research & Therapy. 12: R106. PMID 20509944 DOI: 10.1186/Ar3039 |
0.383 |
|
| 2010 |
Kang YS, Li Y, Dai C, Kiss LP, Wu C, Liu Y. Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria. Kidney International. 78: 363-73. PMID 20505657 DOI: 10.1038/Ki.2010.137 |
0.433 |
|
| 2010 |
Han YC, Yu YP, Nelson J, Wu C, Wang H, Michalopoulos GK, Luo JH. Interaction of integrin-linked kinase and miniature chromosome maintenance 7-mediating integrin {alpha}7 induced cell growth suppression. Cancer Research. 70: 4375-84. PMID 20460506 DOI: 10.1158/0008-5472.Can-09-4403 |
0.442 |
|
| 2010 |
Shao H, Wu C, Wells A. Phosphorylation of alpha-actinin 4 upon epidermal growth factor exposure regulates its interaction with actin. The Journal of Biological Chemistry. 285: 2591-600. PMID 19920151 DOI: 10.1074/Jbc.M109.035790 |
0.427 |
|
| 2009 |
Fukuda K, Gupta S, Chen K, Wu C, Qin J. The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions. Molecular Cell. 36: 819-30. PMID 20005845 DOI: 10.1016/J.Molcel.2009.11.028 |
0.441 |
|
| 2009 |
Zhao J, Zhang Y, Ithychanda SS, Tu Y, Chen K, Qin J, Wu C. Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling. The Journal of Biological Chemistry. 284: 34308-20. PMID 19833732 DOI: 10.1074/Jbc.M109.045021 |
0.495 |
|
| 2009 |
Petricca G, Leppilampi M, Jiang G, Owen GR, Wiebe C, Tu Y, Koivisto L, Häkkinen L, Wu C, Larjava H. Localization and potential function of kindlin-1 in periodontal tissues. European Journal of Oral Sciences. 117: 518-27. PMID 19758247 DOI: 10.1111/J.1600-0722.2009.00651.X |
0.447 |
|
| 2009 |
Liang X, Sun Y, Ye M, Scimia MC, Cheng H, Martin J, Wang G, Rearden A, Wu C, Peterson KL, Powell HC, Evans SM, Chen J. Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality. Circulation. 120: 568-76. PMID 19652092 DOI: 10.1161/Circulationaha.109.864686 |
0.369 |
|
| 2009 |
Yue W, Sun Q, Landreneau R, Wu C, Siegfried JM, Yu J, Zhang L. Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression. Cancer Research. 69: 6339-46. PMID 19584278 DOI: 10.1158/0008-5472.Can-09-0398 |
0.35 |
|
| 2009 |
Apte U, Gkretsi V, Bowen WC, Mars WM, Luo JH, Donthamsetty S, Orr A, Monga SP, Wu C, Michalopoulos GK. Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase. Hepatology (Baltimore, Md.). 50: 844-51. PMID 19575460 DOI: 10.1002/Hep.23059 |
0.314 |
|
| 2009 |
Zhang Y, Tu Y, Zhao J, Chen K, Wu C. Reversion-induced LIM interaction with Src reveals a novel Src inactivation cycle. The Journal of Cell Biology. 184: 785-92. PMID 19307596 DOI: 10.1083/Jcb.200810155 |
0.347 |
|
| 2009 |
Akhtar N, Marlow R, Lambert E, Schatzmann F, Lowe ET, Cheung J, Katz E, Li W, Wu C, Dedhar S, Naylor MJ, Streuli CH. Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation. Development (Cambridge, England). 136: 1019-27. PMID 19211680 DOI: 10.1242/Dev.028423 |
0.5 |
|
| 2009 |
Yang Y, Wang X, Hawkins CA, Chen K, Vaynberg J, Mao X, Tu Y, Zuo X, Wang J, Wang YX, Wu C, Tjandra N, Qin J. Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase. The Journal of Biological Chemistry. 284: 5836-44. PMID 19117955 DOI: 10.1074/Jbc.M805319200 |
0.477 |
|
| 2009 |
Ithychanda SS, Das M, Ma YQ, Ding K, Wang X, Gupta S, Wu C, Plow EF, Qin J. Migfilin, a molecular switch in regulation of integrin activation. The Journal of Biological Chemistry. 284: 4713-22. PMID 19074766 DOI: 10.1074/Jbc.M807719200 |
0.418 |
|
| 2008 |
Larjava H, Plow EF, Wu C. Kindlins: essential regulators of integrin signalling and cell-matrix adhesion. Embo Reports. 9: 1203-8. PMID 18997731 DOI: 10.1038/Embor.2008.202 |
0.503 |
|
| 2008 |
Gkretsi V, Apte U, Mars WM, Bowen WC, Luo JH, Yang Y, Yu YP, Orr A, St-Arnaud R, Dedhar S, Kaestner KH, Wu C, Michalopoulos GK. Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly. Hepatology (Baltimore, Md.). 48: 1932-41. PMID 18846549 DOI: 10.1002/Hep.22537 |
0.425 |
|
| 2008 |
Papachristou DJ, Gkretsi V, Rao UN, Papachristou GI, Papaefthymiou OA, Basdra EK, Wu C, Papavassiliou AG. Expression of integrin-linked kinase and its binding partners in chondrosarcoma: association with prognostic significance. European Journal of Cancer (Oxford, England : 1990). 44: 2518-25. PMID 18722108 DOI: 10.1016/J.Ejca.2008.07.021 |
0.436 |
|
| 2008 |
Wang X, Fukuda K, Byeon IJ, Velyvis A, Wu C, Gronenborn A, Qin J. The structure of α-Parvin CH2-paxillin LD1 complex reveals a novel modular recognition for focal adhesion assembly Journal of Biological Chemistry. 283: 21113-21119. PMID 18508764 DOI: 10.1074/Jbc.M801270200 |
0.324 |
|
| 2008 |
Shi X, Wu C. A suppressive role of mitogen inducible gene-2 in mesenchymal cancer cell invasion. Molecular Cancer Research : McR. 6: 715-24. PMID 18505917 DOI: 10.1158/1541-7786.Mcr-07-2026 |
0.42 |
|
| 2008 |
Shi X, Qu H, Kretzler M, Wu C. Roles of PINCH-2 in regulation of glomerular cell shape change and fibronectin matrix deposition. American Journal of Physiology. Renal Physiology. 295: F253-63. PMID 18480182 DOI: 10.1152/Ajprenal.00070.2008 |
0.467 |
|
| 2008 |
Ma YQ, Qin J, Wu C, Plow EF. Kindlin-2 (Mig-2): a co-activator of beta3 integrins. The Journal of Cell Biology. 181: 439-46. PMID 18458155 DOI: 10.1083/Jcb.200710196 |
0.367 |
|
| 2008 |
Helmick L, Antúnez de Mayolo A, Zhang Y, Cheng CM, Watkins SC, Wu C, LeDuc PR. Spatiotemporal response of living cell structures in Dictyostelium discoideum with semiconductor quantum dots. Nano Letters. 8: 1303-8. PMID 18386936 DOI: 10.1021/Nl073144L |
0.352 |
|
| 2008 |
Chen K, Tu Y, Zhang Y, Blair HC, Zhang L, Wu C. PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells. The Journal of Biological Chemistry. 283: 2508-17. PMID 18063582 DOI: 10.1074/Jbc.M707307200 |
0.381 |
|
| 2007 |
Wu C. Focal adhesion: a focal point in current cell biology and molecular medicine Cell Adhesion &Amp; Migration. 1: 13-18. PMID 19262093 DOI: 10.4161/cam.1.1.4081 |
0.432 |
|
| 2007 |
Hu K, Wu C, Mars WM, Liu Y. Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling. The Journal of Clinical Investigation. 117: 3821-32. PMID 18037995 DOI: 10.1172/Jci32301 |
0.386 |
|
| 2007 |
Kim SM, Kim N, Lee S, Kim do K, Lee YM, Ahn SH, Song JH, Choi BK, Wu C, Jung KY. TGF-beta1-induced PINCH-1-ILK-alpha-parvin complex formation regulates mesangial cell proliferation and hypertrophy. Experimental & Molecular Medicine. 39: 514-23. PMID 17934340 DOI: 10.1038/Emm.2007.57 |
0.363 |
|
| 2007 |
Zhang W, Wu Y, Wu C, Gunst SJ. Integrin-linked kinase regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle. The Journal of Biological Chemistry. 282: 34568-80. PMID 17897939 DOI: 10.1074/Jbc.M704966200 |
0.403 |
|
| 2007 |
Papachristou DJ, Gkretsi V, Tu Y, Shi X, Chen K, Larjava H, Rao UNM, Wu C. Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcoma Histopathology. 51: 499-508. PMID 17711449 DOI: 10.1111/J.1365-2559.2007.02791.X |
0.317 |
|
| 2007 |
Li Y, Dai C, Wu C, Liu Y. PINCH-1 promotes tubular epithelial-to-mesenchymal transition by interacting with integrin-linked kinase. Journal of the American Society of Nephrology : Jasn. 18: 2534-43. PMID 17656471 DOI: 10.1681/Asn.2007030315 |
0.466 |
|
| 2007 |
Ren B, Yu YP, Tseng GC, Wu C, Chen K, Rao UN, Nelson J, Michalopoulos GK, Luo JH. Analysis of integrin alpha7 mutations in prostate cancer, liver cancer, glioblastoma multiforme, and leiomyosarcoma. Journal of the National Cancer Institute. 99: 868-80. PMID 17551147 DOI: 10.1093/Jnci/Djk199 |
0.366 |
|
| 2007 |
Shi X, Ma YQ, Tu Y, Chen K, Wu S, Fukuda K, Qin J, Plow EF, Wu C. The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility. The Journal of Biological Chemistry. 282: 20455-66. PMID 17513299 DOI: 10.1074/Jbc.M611680200 |
0.497 |
|
| 2007 |
Wang Y, Chang J, Chen KD, Li S, Li JY, Wu C, Chien S. Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress. Proceedings of the National Academy of Sciences of the United States of America. 104: 8875-9. PMID 17496149 DOI: 10.1073/Pnas.0703088104 |
0.336 |
|
| 2007 |
Gkretsi V, Mars WM, Bowen WC, Barua L, Yang Y, Guo L, St-Arnaud R, Dedhar S, Wu C, Michalopoulos GK. Loss of integrin linked kinase from mouse hepatocytes in vitro and in vivo results in apoptosis and hepatitis. Hepatology (Baltimore, Md.). 45: 1025-34. PMID 17385211 DOI: 10.1002/Hep.21540 |
0.466 |
|
| 2007 |
Gkretsi V, Bowen WC, Yang Y, Wu C, Michalopoulos GK. Integrin-linked kinase is involved in matrix-induced hepatocyte differentiation. Biochemical and Biophysical Research Communications. 353: 638-43. PMID 17194454 DOI: 10.1016/J.Bbrc.2006.12.091 |
0.435 |
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| 2007 |
Jung KY, Chen K, Kretzler M, Wu C. TGF-beta1 regulates the PINCH-1-integrin-linked kinase-alpha-parvin complex in glomerular cells. Journal of the American Society of Nephrology : Jasn. 18: 66-73. PMID 17167118 DOI: 10.1681/Asn.2006050421 |
0.425 |
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| 2006 |
Chen X, Li Z, Feng Z, Wang J, Ouyang C, Liu W, Fu B, Cai G, Wu C, Wei R, Wu D, Hong Q. Integrin-linked kinase induces both senescence-associated alterations and extracellular fibronectin assembly in aging cardiac fibroblasts. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 61: 1232-45. PMID 17234816 DOI: 10.1093/Gerona/61.12.1232 |
0.465 |
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| 2006 |
Gozgit JM, Pentecost BT, Marconi SA, Otis CN, Wu C, Arcaro KF. Use of an aggressive MCF-7 cell line variant, TMX2-28, to study cell invasion in breast cancer. Molecular Cancer Research : McR. 4: 905-13. PMID 17189381 DOI: 10.1158/1541-7786.Mcr-06-0147 |
0.357 |
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| 2006 |
Belvindrah R, Nalbant P, Ding S, Wu C, Bokoch GM, Müller U. Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development. Molecular and Cellular Neurosciences. 33: 109-25. PMID 16914328 DOI: 10.1016/J.Mcn.2006.06.013 |
0.404 |
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| 2006 |
Dai C, Stolz DB, Bastacky SI, St-Arnaud R, Wu C, Dedhar S, Liu Y. Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling. Journal of the American Society of Nephrology : Jasn. 17: 2164-75. PMID 16837631 DOI: 10.1681/Asn.2006010033 |
0.385 |
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| 2006 |
Zhang Y, Tu Y, Gkretsi V, Wu C. Migfilin interacts with vasodilator-stimulated phosphoprotein (VASP) and regulates VASP localization to cell-matrix adhesions and migration. The Journal of Biological Chemistry. 281: 12397-407. PMID 16531412 DOI: 10.1074/Jbc.M512107200 |
0.489 |
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| 2005 |
Yaroslavskiy BB, Zhang Y, Kalla SE, García Palacios V, Sharrow AC, Li Y, Zaidi M, Wu C, Blair HC. NO-dependent osteoclast motility: reliance on cGMP-dependent protein kinase I and VASP. Journal of Cell Science. 118: 5479-87. PMID 16291726 DOI: 10.1242/Jcs.02655 |
0.421 |
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| 2005 |
Chen H, Huang XN, Yan W, Chen K, Guo L, Tummalapali L, Dedhar S, St-Arnaud R, Wu C, Sepulveda JL. Role of the integrin-linked kinase/PINCH1/alpha-parvin complex in cardiac myocyte hypertrophy. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 1342-56. PMID 16170337 DOI: 10.1038/Labinvest.3700345 |
0.391 |
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| 2005 |
Sepulveda JL, Gkretsi V, Wu C. Assembly and signaling of adhesion complexes. Current Topics in Developmental Biology. 68: 183-225. PMID 16125000 DOI: 10.1016/S0070-2153(05)68007-6 |
0.479 |
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| 2005 |
Wu C. PINCH, N(i)ck and the ILK: network wiring at cell-matrix adhesions. Trends in Cell Biology. 15: 460-6. PMID 16084094 DOI: 10.1016/J.Tcb.2005.07.002 |
0.405 |
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| 2005 |
Xu Z, Fukuda T, Li Y, Zha X, Qin J, Wu C. Molecular dissection of PINCH-1 reveals a mechanism of coupling and uncoupling of cell shape modulation and survival. The Journal of Biological Chemistry. 280: 27631-7. PMID 15941716 DOI: 10.1074/Jbc.M504189200 |
0.445 |
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| 2005 |
Yang Y, Guo L, Blattner SM, Mundel P, Kretzler M, Wu C. Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival. Journal of the American Society of Nephrology : Jasn. 16: 1966-76. PMID 15872073 DOI: 10.1681/Asn.2004121112 |
0.423 |
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| 2005 |
Qian Y, Zhong X, Flynn DC, Zheng JZ, Qiao M, Wu C, Dedhar S, Shi X, Jiang BH. ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling. Oncogene. 24: 3154-65. PMID 15735674 DOI: 10.1038/Sj.Onc.1208525 |
0.473 |
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| 2005 |
Vaynberg J, Fukuda T, Chen K, Vinogradova O, Velyvis A, Tu Y, Ng L, Wu C, Qin J. Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility. Molecular Cell. 17: 513-23. PMID 15721255 DOI: 10.1016/J.Molcel.2004.12.031 |
0.346 |
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| 2005 |
Wu C. Migfilin and its binding partners: from cell biology to human diseases. Journal of Cell Science. 118: 659-64. PMID 15701922 DOI: 10.1242/Jcs.01639 |
0.486 |
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| 2005 |
Gkretsi V, Zhang Y, Tu Y, Chen K, Stolz DB, Yang Y, Watkins SC, Wu C. Physical and functional association of migfilin with cell-cell adhesions. Journal of Cell Science. 118: 697-710. PMID 15671069 DOI: 10.1242/Jcs.01638 |
0.421 |
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| 2005 |
Kucik DF, Wu C. Cell-adhesion assays. Methods in Molecular Biology (Clifton, N.J.). 294: 43-54. PMID 15576904 DOI: 10.1385/1-59259-860-9:043 |
0.416 |
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| 2004 |
Li Z, Chen X, Xie Y, Shi S, Feng Z, Fu B, Zhang X, Cai G, Wu C, Wu D, Gu Y. Expression and significance of integrin-linked kinase in cultured cells, normal tissue, and diseased tissue of aging rat kidneys. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 59: 984-96. PMID 15528771 DOI: 10.1093/Gerona/59.10.B984 |
0.385 |
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| 2004 |
Zhang Y, Chen K, Tu Y, Wu C. Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival. The Journal of Biological Chemistry. 279: 41695-705. PMID 15284246 DOI: 10.1074/Jbc.M401563200 |
0.377 |
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| 2004 |
Wu C. The PINCH-ILK-parvin complexes: assembly, functions and regulation. Biochimica Et Biophysica Acta. 1692: 55-62. PMID 15246679 DOI: 10.1016/J.Bbamcr.2004.01.006 |
0.458 |
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| 2003 |
Fukuda T, Chen K, Shi X, Wu C. PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival. The Journal of Biological Chemistry. 278: 51324-33. PMID 14551191 DOI: 10.1074/Jbc.M309122200 |
0.425 |
|
| 2003 |
Attwell S, Mills J, Troussard A, Wu C, Dedhar S. Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN. Molecular Biology of the Cell. 14: 4813-25. PMID 12960424 DOI: 10.1091/Mbc.E03-05-0308 |
0.464 |
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| 2003 |
Li J, Rao H, Burkin D, Kaufman SJ, Wu C. The muscle integrin binding protein (MIBP) interacts with α7β1 integrin and regulates cell adhesion and laminin matrix deposition Developmental Biology. 261: 209-219. PMID 12941630 DOI: 10.1016/S0012-1606(03)00304-X |
0.407 |
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| 2003 |
Li Y, Yang J, Dai C, Wu C, Liu Y. Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis. The Journal of Clinical Investigation. 112: 503-16. PMID 12925691 DOI: 10.1172/Jci17913 |
0.39 |
|
| 2003 |
Velyvis A, Vaynberg J, Yang Y, Vinogradova O, Zhang Y, Wu C, Qin J. Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling. Nature Structural Biology. 10: 558-64. PMID 12794636 DOI: 10.1038/Nsb938 |
0.433 |
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| 2003 |
Tu Y, Wu S, Shi X, Chen K, Wu C. Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation. Cell. 113: 37-47. PMID 12679033 DOI: 10.1016/S0092-8674(03)00163-6 |
0.465 |
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| 2003 |
Fukuda T, Guo L, Shi X, Wu C. CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt. The Journal of Cell Biology. 160: 1001-8. PMID 12654898 DOI: 10.1083/Jcb.200212113 |
0.383 |
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| 2002 |
Zhang Y, Chen K, Tu Y, Velyvis A, Yang Y, Qin J, Wu C. Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites. Journal of Cell Science. 115: 4777-86. PMID 12432066 DOI: 10.1242/Jcs.00166 |
0.425 |
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| 2002 |
Zhang Y, Chen K, Guo L, Wu C. Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration. The Journal of Biological Chemistry. 277: 38328-38. PMID 12167643 DOI: 10.1074/Jbc.M205576200 |
0.502 |
|
| 2002 |
Kassis J, Maeda A, Teramoto N, Takada K, Wu C, Klein G, Wells A. EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness. International Journal of Cancer. 99: 644-51. PMID 12115496 DOI: 10.1002/Ijc.10382 |
0.384 |
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| 2002 |
Guo L, Wu C. Regulation of fibronectin matrix deposition and cell proliferation by the PINCH-ILK-CH-ILKBP complex. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1298-300. PMID 12060675 DOI: 10.1096/Fj.02-0089Fje |
0.407 |
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| 2002 |
Goicoechea SM, Tu Y, Hua Y, Chen K, Shen TL, Guan JL, Wu C. Nck-2 interacts with focal adhesion kinase and modulates cell motility. The International Journal of Biochemistry & Cell Biology. 34: 791-805. PMID 11950595 DOI: 10.1016/S1357-2725(02)00002-X |
0.459 |
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| 2002 |
Zhang Y, Guo L, Chen K, Wu C. A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration. The Journal of Biological Chemistry. 277: 318-26. PMID 11694512 DOI: 10.1074/Jbc.M108257200 |
0.491 |
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| 2001 |
Wu C, Dedhar S. Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes. The Journal of Cell Biology. 155: 505-10. PMID 11696562 DOI: 10.1083/Jcb.200108077 |
0.504 |
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| 2001 |
Guo L, Sanders PW, Woods A, Wu C. The distribution and regulation of integrin-linked kinase in normal and diabetic kidneys American Journal of Pathology. 159: 1735-1742. PMID 11696434 DOI: 10.1016/S0002-9440(10)63020-9 |
0.396 |
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| 2001 |
Tu Y, Huang Y, Zhang Y, Hua Y, Wu C. A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading. Journal of Cell Biology. 153: 585-598. PMID 11331308 DOI: 10.1083/Jcb.153.3.585 |
0.327 |
|
| 2001 |
Tu Y, Kucik DF, Wu C. Identification and kinetic analysis of the interaction between Nck-2 and DOCK180. Febs Letters. 491: 193-9. PMID 11240126 DOI: 10.1016/S0014-5793(01)02195-0 |
0.347 |
|
| 2001 |
Tu Y, Liang L, Frank SJ, Wu C. Src homology 3 domain-dependent interaction of Nck-2 with insulin receptor substrate-1 Biochemical Journal. 354: 315-322. PMID 11171109 DOI: 10.1042/0264-6021:3540315 |
0.346 |
|
| 2001 |
Velyvis A, Yang Y, Wu C, Qin J. Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain. Journal of Biological Chemistry. 276: 4932-4939. PMID 11078733 DOI: 10.1074/Jbc.M007632200 |
0.402 |
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| 2000 |
Huang Y, Li J, Zhang Y, Wu C. The roles of integrin-linked kinase in the regulation of myogenic differentiation. Journal of Cell Biology. 150: 861-872. PMID 10953009 DOI: 10.1083/Jcb.150.4.861 |
0.422 |
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| 2000 |
Wu C. How inside meets outside: Guidebook to the Extracellular Matrix, Anchor, and Adhesion Proteins (2nd edn) edited by Thomas Kreis and Ronald Vale Trends in Cell Biology. 10: 402. DOI: 10.1016/S0962-8924(00)01746-3 |
0.46 |
|
| 1999 |
Tu Y, Wu C. Cloning, expression and characterization of a novel human Ras-related protein that is regulated by glucocorticoid hormone. Biochimica Et Biophysica Acta. 1489: 452-456. PMID 10673050 DOI: 10.1016/S0167-4781(99)00197-9 |
0.375 |
|
| 1999 |
Li J, Mayne R, Wu C. A Novel Muscle-Specific β1 Integrin Binding Protein (Mibp) That Modulates Myogenic Differentiation Journal of Cell Biology. 147: 1391-1398. PMID 10613898 DOI: 10.1083/Jcb.147.7.1391 |
0.4 |
|
| 1999 |
Huang Y, Wu C. Integrin-linked kinase and associated proteins (review). International Journal of Molecular Medicine. 3: 563-72. PMID 10341284 DOI: 10.3892/Ijmm.3.6.563 |
0.457 |
|
| 1999 |
Tu Y, Li F, Goicoechea S, Wu C. The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells. Molecular and Cellular Biology. 19: 2425-2434. PMID 10022929 DOI: 10.1128/Mcb.19.3.2425 |
0.478 |
|
| 1999 |
Tu Y, Li F, Wu C. Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways. Molecular Biology of the Cell. 9: 3367-82. PMID 9843575 DOI: 10.1091/Mbc.9.12.3367 |
0.4 |
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| 1998 |
Xie W, Li F, Kudlow JE, Wu C. Expression of the integrin-linked kinase (ILK) in mouse skin: loss of expression in suprabasal layers of the epidermis and up-regulation by erbB-2. The American Journal of Pathology. 153: 367-72. PMID 9708797 DOI: 10.1016/S0002-9440(10)65580-0 |
0.431 |
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| 1998 |
Wu C, Keightley SY, Leung-Hagesteijn C, Radeva G, Coppolino M, Goicoechea S, McDonald JA, Dedhar S. Integrin-linked protein kinase regulates fibronectin matrix assembly, E- cadherin expression, and tumorigenicity Journal of Biological Chemistry. 273: 528-536. PMID 9417112 DOI: 10.1074/Jbc.273.1.528 |
0.493 |
|
| 1997 |
Li F, Liu J, Mayne R, Wu C. Identification And Characterization Of A Mouse Protein Kinase That Is Highly Homologous To Human Integrin-Linked Kinase Biochimica Et Biophysica Acta. 1358: 215-220. PMID 9366252 DOI: 10.1016/S0167-4889(97)00089-X |
0.345 |
|
| 1997 |
Wu C, McDonald J, Dedhar S. Overexpression of integrin linked kinase (ILK) induces oncogenic transformation and fibronectin matrix assembly in epithelial cells Matrix Biology. 16: 69. DOI: 10.1016/S0945-053X(97)90080-9 |
0.325 |
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| 1996 |
Wu C, Hughes PE, Ginsberg MH, Mcdonald JA. Identification of a new biological function for the integrin αvβ3: Initiation of fibronectin matrix assembly Cell Communication and Adhesion. 4: 149-158. PMID 8969861 DOI: 10.3109/15419069609014219 |
0.4 |
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| 1996 |
Hughes PE, Diaz-Gonzalez F, Leong L, Wu C, McDonald JA, Shattil SJ, Ginsberg MH. Breaking the integrin hinge. A defined structural constraint regulates integrin signaling. The Journal of Biological Chemistry. 271: 6571-4. PMID 8636068 DOI: 10.1074/Jbc.271.12.6571 |
0.398 |
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| 1996 |
Wu C, 文雄 深. Integrin Mediated Fibronectin Matrix Assembly Trends in Glycoscience and Glycotechnology. 8: 315-325. DOI: 10.4052/Tigg.8.315 |
0.349 |
|
| 1995 |
Wu C, Keivenst VM, O'Toole TE, McDonald JA, Ginsberg MH. Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix Cell. 83: 715-724. PMID 8521488 DOI: 10.1016/0092-8674(95)90184-1 |
0.416 |
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| 1994 |
Hsieh JC, Wu C, Chung AE. The binding of fibronectin to entactin is mediated through the 29 kDa amino terminal fragment of fibronectin and the G2 domain of entactin. Biochemical and Biophysical Research Communications. 199: 1509-17. PMID 8147897 DOI: 10.1006/Bbrc.1994.1402 |
0.32 |
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| 1993 |
Chung AE, Dong LJ, Wu C, Durkin ME. Biological functions of entactin. Kidney International. 43: 13-9. PMID 8433553 DOI: 10.1038/Ki.1993.4 |
0.431 |
|
| 1992 |
Mosher DF, Sottile J, Wu C, McDonald JA. Assembly of extracellular matrix Current Opinion in Cell Biology. 4: 810-818. PMID 1419058 DOI: 10.1016/0960-9822(92)90138-Z |
0.335 |
|
| 1991 |
Wu C, Reing J, Chung AE. Entactin forms a complex with fibronectin and co-localizes in the extracellular matrix of the embryonal carcinoma-derived 4CQ cell line. Biochemical and Biophysical Research Communications. 178: 1219-25. PMID 1872841 DOI: 10.1016/0006-291X(91)91023-6 |
0.368 |
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