Michael M. Lederman - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Pathology, Cell Biology, Immunology

355 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Harper J, Betts MR, Lichterfeld M, Müller-Trutwin M, Margolis D, Bar KJ, Li JZ, McCune JM, Lewin SR, Kulpa D, Ávila-Ríos S, Diallo DD, Lederman MM, Paiardini M. Erratum to: Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner? Pathogens & Immunity. 8: 179-222. PMID 38505662 DOI: 10.20411/pai.v8i2.696  0.373
2024 Harper J, Betts MR, Lichterfeld M, Müller-Trutwin M, Margolis D, Bar KJ, Li JZ, McCune JM, Lewin SR, Kulpa D, Diallo DD, Lederman MM, Paiardini M. Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner? Pathogens & Immunity. 8: 115-157. PMID 38455668 DOI: 10.20411/pai.v8i2.665  0.467
2024 Shivakoti R, Giganti MJ, Lederman MM, Ketchum R, Brummel S, Moisi D, Dadabhai S, Moodley D, Violari A, Chinula L, Owor M, Gupta A, Currier JS, Taha TE, Fowler MG. Systemic inflammation in pregnant women with HIV: relationship with HIV treatment regimen and preterm delivery. Aids (London, England). PMID 38411599 DOI: 10.1097/QAD.0000000000003877  0.346
2023 Winchester NE, Panigrahi S, Haria A, Chakraborty A, Su X, Chen B, Morris SR, Clagett BM, Juchnowski SM, Yadavalli R, Villinger F, Paiardini M, Harth K, Kashyap VS, Calabrese LH, ... ... Lederman MM, et al. Cytomegalovirus Infection Facilitates the Costimulation of CD57+CD28- CD8 T Cells in HIV Infection and Atherosclerosis via the CD2-LFA-3 Axis. Journal of Immunology (Baltimore, Md. : 1950). PMID 38047900 DOI: 10.4049/jimmunol.2300267  0.364
2023 Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Crain CR, Traunbauer AK, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, ... ... Lederman MM, et al. Viral and host mediators of non-suppressible HIV-1 viremia. Nature Medicine. PMID 37957382 DOI: 10.1038/s41591-023-02611-1  0.479
2023 Freeman ML, Hossain MB, Burrowes SAB, Jeudy J, Bui R, Moisi D, Mitchell SE, Khambaty M, Weiss RG, Lederman MM, Bagchi S. Association of Soluble Markers of Inflammation With Peri-coronary Artery Inflammation in People With and Without HIV Infection and Without Cardiovascular Disease. Open Forum Infectious Diseases. 10: ofad328. PMID 37636516 DOI: 10.1093/ofid/ofad328  0.35
2023 Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, Jilg N, Kaseke C, ... ... Lederman MM, et al. Viral and Host Mediators of Non-Suppressible HIV-1 Viremia. Medrxiv : the Preprint Server For Health Sciences. PMID 37034605 DOI: 10.1101/2023.03.30.23287124  0.467
2023 Funderburg NT, Shive CL, Chen Z, Tatsuoka C, Bowman ER, Longenecker CT, McComsey GA, Clagett BM, Dorazio D, Freeman ML, Sieg SF, Moisi D, Anthony DD, Jacobson JM, Stein SL, ... ... Lederman MM, et al. IL-6 blockade with tocilizumab diminishes indices of inflammation that are linked to mortality in treated HIV infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 37011013 DOI: 10.1093/cid/ciad199  0.318
2023 Hastie E, Moser C, Sun X, Lennox J, Hsue PY, Bosch RJ, Deeks S, Meneses MV, Lederman MM, Hunt P, Henrich TJ, Marconi VC, Gianella S. Effect of Immune-Modulatory Interventions on Asymptomatic Cytomegalovirus Shedding during Suppressive Antiretroviral Therapy. The Journal of Infectious Diseases. PMID 36881933 DOI: 10.1093/infdis/jiad060  0.398
2023 Etemad B, Sun X, Li Y, Melberg M, Moisi D, Gottlieb R, Ahmed H, Aga E, Bosch RJ, Acosta EP, Yuki Y, Martin MP, Carrington M, Gandhi RT, Jacobson JM, ... ... Lederman MM, et al. HIV post-treatment controllers have distinct immunological and virological features. Proceedings of the National Academy of Sciences of the United States of America. 120: e2218960120. PMID 36877848 DOI: 10.1073/pnas.2218960120  0.472
2023 Poveda E, Fitzgerald W, Reglero C, Pérez-González A, Mariño A, Álvarez H, Valcarce N, Llibre JM, Guillén SM, Fernández MAM, Ruiz-Mateos E, Margolis L, Lederman MM, Freeman ML. IL-18 and IL-3 in Extracellular Vesicles: Biomarkers for Durable Elite Control of HIV-1. The Journal of Infectious Diseases. PMID 36790818 DOI: 10.1093/infdis/jiad042  0.323
2022 Lian X, Seiger KW, Parsons EM, Gao C, Sun W, Gladkov GT, Roseto IC, Einkauf KB, Osborn MR, Chevalier JM, Jiang C, Blackmer J, Carrington M, Rosenberg ES, Lederman MM, et al. Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy. Cell Host & Microbe. PMID 36596305 DOI: 10.1016/j.chom.2022.12.002  0.363
2022 Pino M, Pagliuzza A, Pampena MB, Deleage C, Viox EG, Nguyen K, Shim I, Zhang A, Harper JL, Samer S, King CT, Cervasi B, Gill KP, Ehnert S, Jean SM, ... ... Lederman MM, et al. Limited impact of fingolimod treatment during the initial weeks of ART in SIV-infected rhesus macaques. Nature Communications. 13: 5055. PMID 36030289 DOI: 10.1038/s41467-022-32698-y  0.355
2022 Freeman ML, Clagett BM, Moisi D, Yeh E, Morris CD, Ryu A, Rodriguez B, Stein JH, Deeks SG, Currier JS, Hsue PY, Anthony DD, Calabrese LH, Ribaudo HJ, Lederman MM. Methotrexate Inhibits T Cell Proliferation but Not Inflammatory Cytokine Expression to Modulate Immunity in People Living With HIV. Frontiers in Immunology. 13: 924718. PMID 35967371 DOI: 10.3389/fimmu.2022.924718  0.33
2022 Araújo-Pereira M, Barreto-Duarte B, Arriaga MB, Musselwhite LW, Vinhaes CL, Belaunzaran-Zamudio PF, Rupert A, Montaner LJ, Lederman MM, Sereti I, Madero JGS, Andrade BB. Relationship Between Anemia and Systemic Inflammation in People Living With HIV and Tuberculosis: A Sub-Analysis of the CADIRIS Clinical Trial. Frontiers in Immunology. 13: 916216. PMID 35812431 DOI: 10.3389/fimmu.2022.916216  0.371
2022 Premeaux TA, Moser CB, McKhann A, Hoenigl M, Yeung ST, Pang APS, Corley MJ, Lederman MM, Landay AL, Gianella S, Ndhlovu LC. Monitoring Circulating Immune Checkpoint Proteins as Predictors of Non-AIDS Morbid Events in People With HIV Initiating Antiretroviral Therapy. Open Forum Infectious Diseases. 9: ofab570. PMID 35146038 DOI: 10.1093/ofid/ofab570  0.436
2021 Premeaux TA, Moser CB, McKhann A, Hoenigl M, Laws EI, Aquino DL, Lederman MM, Landay AL, Gianella S, Ndhlovu LC. Plasma galectin-9 as a predictor of adverse non-AIDS events in persons with chronic HIV during suppressive antiretroviral therapy. Aids (London, England). 35: 2489-2495. PMID 34366381 DOI: 10.1097/QAD.0000000000003048  0.393
2021 Nganou-Makamdop K, Talla A, Sharma AA, Darko S, Ransier A, Laboune F, Chipman JG, Beilman GJ, Hoskuldsson T, Fourati S, Schmidt TE, Arumugam S, Lima NS, Moon D, Callisto S, ... ... Lederman MM, et al. Translocated microbiome composition determines immunological outcome in treated HIV infection. Cell. PMID 34237254 DOI: 10.1016/j.cell.2021.05.023  0.416
2021 Hurwitz SJ, Tao S, Gavegnano C, Jiang Y, Tressler R, Tsibris A, Del Rio C, Overton ET, Lederman MM, Kantor A, Moser C, Kohler JJ, Lennox J, Marconi VC, Flexner C, et al. Pharmacokinetics of Ruxolitinib in HIV Suppressed Individuals on Antiretroviral Agents Therapy from the ACTG A5336 Study. Journal of Clinical Pharmacology. PMID 34169526 DOI: 10.1002/jcph.1930  0.305
2021 Schnittman SR, Byakwaga H, Boum Y, Kabakyenga J, Matthews LT, Burdo TH, Huang Y, Tracy RP, Haberer JE, Kembabazi A, Kaida A, Moisi D, Lederman MM, Bangsberg DR, Martin JN, et al. Changes in Immune Activation During Pregnancy and the Postpartum Period in Treated HIV Infection. Open Forum Infectious Diseases. 8: ofab245. PMID 34159218 DOI: 10.1093/ofid/ofab245  0.376
2021 Shive CL, Freeman ML, Younes SA, Kowal CM, Canaday DH, Rodriguez B, Lederman MM, Anthony DD. Markers of T Cell Exhaustion and Senescence and Their Relationship to Plasma TGF-β Levels in Treated HIV+ Immune Non-responders. Frontiers in Immunology. 12: 638010. PMID 33868264 DOI: 10.3389/fimmu.2021.638010  0.413
2021 Marconi VC, Moser C, Gavegnano C, Deeks SG, Lederman MM, Overton ET, Tsibris A, Hunt PW, Kantor A, Sekaly RP, Tressler R, Flexner C, Hurwitz SJ, Moisi D, Clagett B, et al. Randomized Trial of Ruxolitinib in Antiretroviral-Treated Adults with HIV. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 33693561 DOI: 10.1093/cid/ciab212  0.411
2020 Bowman ER, Cameron CM, Richardson B, Kulkarni M, Gabriel J, Cichon MJ, Riedl KM, Mustafa Y, Cartwright M, Snyder B, Raman SV, Zidar DA, Koletar SL, Playford MP, Mehta NN, ... ... Lederman MM, et al. Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms. Plos Pathogens. 16: e1008869. PMID 33002093 DOI: 10.1371/journal.ppat.1008869  0.362
2020 Panigrahi S, Chen B, Fang M, Potashnikova D, Komissarov AA, Lebedeva A, Michaelson GM, Wyrick JM, Morris SR, Sieg SF, Paiardini M, Villinger FJ, Harth K, Kashyap VS, Cameron MJ, ... ... Lederman MM, et al. CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis. Plos Pathogens. 16: e1008885. PMID 32976527 DOI: 10.1371/journal.ppat.1008885  0.405
2020 Poveda E, Tabernilla A, Fitzgerald W, Salgado-Barreira Á, Grandal M, Pérez A, Mariño A, Álvarez H, Valcarce N, González-García J, Bernardino JI, Gutierrez F, Fujioka H, Crespo M, Ruiz-Mateos E, ... ... Lederman MM, et al. Massive release of CD9+ microvesicles in HIV infection, regardless of virologic control. The Journal of Infectious Diseases. PMID 32603406 DOI: 10.1093/Infdis/Jiaa375  0.544
2020 Ruiz-Mateos E, Poveda E, Lederman MM. Antiretroviral Treatment for HIV Elite Controllers? Pathogens & Immunity. 5: 121-133. PMID 32582872 DOI: 10.20411/pai.v5i1.364  0.504
2020 Grossman Z, Singh NJ, Simonetti FR, Lederman MM, Douek DC, Deeks SG. 'Rinse and Replace': Boosting T Cell Turnover To Reduce HIV-1 Reservoirs. Trends in Immunology. PMID 32414695 DOI: 10.1016/J.It.2020.04.003  0.529
2020 Morris SR, Chen B, Mudd JC, Panigrahi S, Shive CL, Sieg SF, Cameron CM, Zidar DA, Funderburg NT, Younes SA, Rodriguez B, Gianella S, Lederman MM, Freeman ML. "Inflammescent" CX3CR1+CD57+ CD8 T cells are generated and expanded by IL-15. Jci Insight. PMID 32369455 DOI: 10.1172/Jci.Insight.132963  0.447
2020 Gianella S, Moser C, Vitomirov A, McKhann A, Layman L, Scott B, Caballero G, Lada S, Bosch RJ, Hoenigl M, Lurain N, Landay A, Lederman MM, Hunt PW, Smith D. Presence of asymptomatic cytomegalovirus and Epstein--Barr virus DNA in blood of persons with HIV starting antiretroviral therapy is associated with non-AIDS clinical events. Aids (London, England). 34: 849-857. PMID 32271250 DOI: 10.1097/QAD.0000000000002484  0.405
2020 Chen B, Morris SR, Panigrahi S, Michaelson GM, Wyrick JM, Komissarov AA, Potashnikova D, Lebedeva A, Younes SA, Harth K, Kashyap VS, Vasilieva E, Margolis L, Zidar DA, Sieg SF, ... ... Lederman MM, et al. Cytomegalovirus Coinfection Is Associated with Increased Vascular-Homing CD57 CD4 T Cells in HIV Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 32229536 DOI: 10.4049/Jimmunol.1900734  0.499
2020 Gianella S, Moser C, Vitomirov A, McKhann A, Layman L, Scott B, Caballero G, Lada S, Bosch RJ, Hoenigl M, Lurain N, Landay A, Lederman MM, Hunt PW, Smith D. Presence of asymptomatic CMV and EBV DNA in blood of persons with HIV starting antiretroviral therapy are associated with non-AIDS clinical events. Aids (London, England). PMID 32004204 DOI: 10.1097/Qad.0000000000002484  0.504
2019 Pino M, Paganini S, Deleage C, Padhan K, Harper JL, King CT, Micci L, Cervasi B, Mudd JC, Gill KP, Jean SM, Easley K, Silvestri G, Estes JD, Petrovas C, ... Lederman MM, et al. Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence. Plos Pathogens. 15: e1008081. PMID 31626660 DOI: 10.1371/Journal.Ppat.1008081  0.515
2019 Jeon D, Chang EG, McGing M, Hartman-Filson M, Sommers M, Lewis E, Balmes JR, Moisi D, Lederman MM, Madsen KA, Woodruff PG, Hunt PW, Huang L. Pneumoproteins are associated with pulmonary function in HIV-infected persons. Plos One. 14: e0223263. PMID 31574118 DOI: 10.1371/Journal.Pone.0223263  0.514
2019 Wang RJ, Moore J, Moisi D, Chang EG, Byanyima P, Kaswabuli S, Musisi E, Sanyu I, Sessolo A, Lalitha R, Worodria W, Davis JL, Crothers K, Lin J, Lederman MM, et al. HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. Plos One. 14: e0216680. PMID 31091258 DOI: 10.1371/Journal.Pone.0216680  0.548
2019 Bowman ER, Kulkarni M, Gabriel J, Cichon MJ, Riedl K, Belury MA, Lake JE, Richardson B, Cameron C, Cameron M, Koletar SL, Lederman MM, Sieg SF, Funderburg NT. Altered Lipidome Composition Is Related to Markers of Monocyte and Immune Activation in Antiretroviral Therapy Treated Human Immunodeficiency Virus (HIV) Infection and in Uninfected Persons. Frontiers in Immunology. 10: 785. PMID 31040846 DOI: 10.3389/Fimmu.2019.00785  0.557
2019 Dorazio D, Kitch DW, Utay NS, Macatangay BJ, Landay A, Brown T, Bosch RJ, Pelger AL, Baum JE, Asaad R, Rodriguez B, Lederman MM. Stability of plasma indices of inflammation/coagulation and homeostasis after fatty and non-fatty meals in treated people with HIV. Journal of Virus Eradication. 5: 28-32. PMID 30800423  0.309
2019 Freeman ML, Panigrahi S, Chen B, Juchnowski S, Sieg SF, Lederman MM, Funderburg NT, Zidar DA. CD8+ T Cell-Derived Tumor Necrosis Factor Can Induce Tissue Factor Expression on Monocytes. The Journal of Infectious Diseases. PMID 30698729 DOI: 10.1093/Infdis/Jiz051  0.455
2019 Dorazio D, Kitch DW, Utay NS, Macatangay BJ, Landay A, Brown T, Bosch RJ, Pelger AL, Baum JE, Asaad R, Rodriguez B, Lederman MM. Stability of plasma indices of inflammation/coagulation and homeostasis after fatty and non-fatty meals in treated people with HIV. Journal of Virus Eradication. 5: 28-32. DOI: 10.1016/S2055-6640(20)30274-0  0.405
2018 Hoenigl M, Moser C, Funderburg N, Bosch R, Kantor A, Zhang Y, Eugen-Olsen J, Finkelman M, Reiser J, Landay A, Moisi D, Lederman MM, Gianella S. Soluble Urokinase Plasminogen Activator Receptor (suPAR) is predictive of Non-AIDS Events during Antiretroviral Therapy-mediated Viral Suppression. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30418519 DOI: 10.1093/Cid/Ciy966  0.458
2018 Webel AR, Willig AL, Liu W, Sattar A, Boswell S, Crane HM, Hunt P, Kitahata M, Matthews WC, Saag MS, Lederman MM, Rodriguez B. Physical Activity Intensity is Associated with Symptom Distress in the CNICS Cohort. Aids and Behavior. PMID 30368620 DOI: 10.1007/S10461-018-2319-7  0.362
2018 Younes SA, Talla A, Pereira Ribeiro S, Saidakova EV, Korolevskaya LB, Shmagel KV, Shive CL, Freeman ML, Panigrahi S, Zweig S, Balderas R, Margolis L, Douek DC, Anthony DD, Pandiyan P, ... ... Lederman MM, et al. Cycling CD4+ T cells in HIV-infected immune nonresponders have mitochondrial dysfunction. The Journal of Clinical Investigation. PMID 30320604 DOI: 10.1172/Jci120245  0.513
2018 Hsue PY, Ribaudo HJ, Deeks SG, Bell T, Ridker PM, Fichtenbaum C, Daar ES, Havlir D, Yeh E, Tawakol A, Lederman M, Currier JS, Stein JH. Safety and Impact of Low-Dose Methotrexate on Endothelial Function and Inflammation in Individuals with Treated Human Immunodeficiency Virus: AIDS Clinical Trials Group Study A5314. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30219823 DOI: 10.1093/Cid/Ciy781  0.469
2018 Sharaf R, Lee GQ, Sun X, Etemad B, Aboukhater LM, Hu Z, Brumme ZL, Aga E, Bosch RJ, Wen Y, Namazi G, Gao C, Acosta EP, Gandhi RT, Jacobson JM, ... ... Lederman MM, et al. HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. The Journal of Clinical Investigation. PMID 30024859 DOI: 10.1172/Jci120549  0.525
2018 Kityo C, Makamdop KN, Rothenberger M, Chipman JG, Hoskuldsson T, Beilman GJ, Grzywacz B, Mugyenyi P, Ssali F, Akondy RS, Anderson J, Schmidt TE, Reimann T, Callisto SP, Schoephoerster J, ... ... Lederman MM, et al. Lymphoid tissue fibrosis is associated with impaired vaccine responses. The Journal of Clinical Investigation. PMID 29781814 DOI: 10.1172/Jci97377  0.462
2018 Utay NS, Kitch DW, Yeh E, Fichtenbaum CJ, Lederman MM, Estes JD, Deleage C, Magyar C, Nelson SD, Klingman KL, Bastow B, Luque AE, McComsey GA, Douek DC, Currier JS, et al. Telmisartan Does Not Improve Lymph Node or Adipose Tissue Fibrosis More Than Continued ART Alone. The Journal of Infectious Diseases. PMID 29401318 DOI: 10.1093/Infdis/Jiy064  0.334
2017 Angelidou K, Hunt PW, Landay AL, Wilson CC, Rodriguez B, Deeks SG, Bosch RJ, Lederman MM. Changes in inflammation but not in T cell activation precede non-AIDS-defining events in a case-control study of patients on long-term antiretroviral therapy. The Journal of Infectious Diseases. PMID 29309629 DOI: 10.1093/Infdis/Jix666  0.368
2017 Shmagel KV, Korolevskaya LB, Saidakova EV, Shmagel NG, Chereshnev VA, Margolis L, Anthony D, Lederman M. HCV coinfection of the HIV-infected patients with discordant CD4+ T-cell response to antiretroviral therapy leads to intense systemic inflammation. Doklady Biological Sciences : Proceedings of the Academy of Sciences of the Ussr, Biological Sciences Sections. 477: 244-247. PMID 29299802 DOI: 10.1134/S0012496617060047  0.485
2017 Shive CL, Judge CJ, Clagett B, Kalayjian RC, Osborn M, Sherman KE, Fichtenbaum C, Gandhi RT, Kang M, Popkin DL, Sieg SF, Lederman MM, Rodriguez B, Anthony DD. Pre-vaccine plasma levels of soluble inflammatory indices negatively predict responses to HAV, HBV, and tetanus vaccines in HCV and HIV infection. Vaccine. PMID 29254840 DOI: 10.1016/J.Vaccine.2017.12.018  0.384
2017 Wang C, Edilova MI, Wagar LE, Mujib S, Singer M, Bernard NF, Croughs T, Lederman MM, Sereti I, Fischl MA, Kremmer E, Ostrowski M, Routy JP, Watts TH. Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy. Journal of Immunology (Baltimore, Md. : 1950). PMID 29222166 DOI: 10.4049/Jimmunol.1601254  0.538
2017 Lederman MM, Pike E. Ten Years HIV Free: An Interview with "The Berlin Patient," Timothy Ray Brown. Pathogens & Immunity. 2: 422-430. PMID 29202113 DOI: 10.20411/pai.v2i3.226  0.359
2017 Belury MA, Bowman E, Gabriel J, Snyder B, Kulkarni M, Palettas M, Mo X, Lake JE, Zidar D, Sieg SF, Rodriguez B, Playford MP, Andrade A, Kuritzkes DR, Mehta NN, ... Lederman MM, et al. Prospective Analysis of Lipid Composition Changes with Antiretroviral Therapy and Immune Activation in Persons Living with HIV. Pathogens & Immunity. 2: 376-403. PMID 29098203 DOI: 10.20411/pai.v2i3.218  0.437
2017 Freeman ML, Morris SR, Lederman MM. CD161 Expression on Mucosa-Associated Invariant T Cells is Reduced in HIV-Infected Subjects Undergoing Antiretroviral Therapy Who Do Not Recover CD4(+) T Cells. Pathogens & Immunity. 2: 335-351. PMID 28868514 DOI: 10.20411/pai.v2i3.136  0.469
2017 Belaunzarán-Zamudio PF, Azzoni L, Canaday DH, Caro-Vega YN, Clagget B, Rassool MS, Rodriguez B, Sanne I, Sereti I, Sierra-Madero JG, Lederman MM. Immunologic Effects of Maraviroc in HIV-Infected Patients with Severe CD4 Lymphopenia Starting Antiretroviral Therapy: A Sub-Study of the CADIRIS Trial. Pathogens & Immunity. 2: 151-177. PMID 28736763 DOI: 10.20411/pai.v2i2.181  0.477
2017 Judge CJ, Kostadinova L, Sherman KE, Butt AA, Falck-Ytter Y, Funderburg NT, Landay AL, Lederman MM, Sieg SF, Sandberg JK, Anthony DD. CD56(bright) NK IL-7Rα expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections. Journal of Leukocyte Biology. PMID 28400540 DOI: 10.1189/Jlb.5A1116-456R  0.474
2017 Nixon DE, Bosch RJ, Chan ES, Funderburg NT, Hodder S, Lake JE, Lederman MM, Klingman KL, Aberg JA. Effects of atorvastatin on biomarkers of immune activation, inflammation, and lipids in virologically suppressed, human immunodeficiency virus-1-infected individuals with low-density lipoprotein cholesterol <130 mg/dL (AIDS Clinical Trials Group Study A5275). Journal of Clinical Lipidology. 11: 61-69. PMID 28391912 DOI: 10.1016/J.Jacl.2016.09.017  0.456
2017 Weber J, Gibson RM, Sácká L, Strunin D, Hodek J, Weberová J, Pávová M, Alouani DJ, Asaad R, Rodriguez B, Lederman MM, Quiñones-Mateu ME. Impaired human immunodeficiency virus type 1 replicative fitness in atypical viremic non-progressor individuals. Aids Research and Therapy. 14: 15. PMID 28331526 DOI: 10.1186/S12981-017-0144-0  0.583
2017 Lee S, Byakwaga H, Boum Y, Burdo TH, Williams KC, Lederman MM, Huang Y, Tracy RP, Cao H, Haberer JE, Kembabazi A, Bangsberg DR, Martin JN, Hunt PW. Immunologic Pathways that Predict Mortality in HIV-Infected Ugandans Initiating ART. The Journal of Infectious Diseases. PMID 28329310 DOI: 10.1093/Infdis/Jix113  0.494
2017 Manion M, Andrade BB, DerSimonian R, Gu W, Rupert A, Musselwhite LW, Sierra-Madero JG, Belaunzaran-Zamudio PF, Sanne I, Lederman MM, Sereti I. Country of residence is associated with distinct inflammatory biomarker signatures in HIV-infected patients. Journal of Virus Eradication. 3: 24-33. PMID 28275455  0.424
2017 Manion M, Andrade BB, DerSimonian R, Gu W, Rupert A, Musselwhite LW, Sierra-Madero JG, Belaunzaran-Zamudio PF, Sanne I, Lederman MM, Sereti I. Country of residence is associated with distinct inflammatory biomarker signatures in HIV-infected patients. Journal of Virus Eradication. 3: 24-33. DOI: 10.1016/S2055-6640(20)30303-4  0.537
2016 Kulkarni M, Bowman E, Gabriel J, Amburgy T, Mayne E, Zidar DA, Maierhofer C, Turner AN, Bazan JA, Koletar SL, Lederman MM, Sieg SF, Funderburg NT. Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection. Open Forum Infectious Diseases. 3: ofw224. PMID 28066794 DOI: 10.1093/Ofid/Ofw224  0.442
2016 Al-Kindi SG, Kim CH, Morris SR, Freeman ML, Funderburg NT, Rodriguez B, McComsey GA, Dalton JE, Simon DI, Lederman MM, Longenecker CT, Zidar DA. Elevated Red Cell Distribution Width (RDW) Identifies Elevated Cardiovascular Disease Risk in Patients with HIV infection. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27828877 DOI: 10.1097/Qai.0000000000001231  0.478
2016 Funderburg NT, Xu D, Playford MP, Joshi AA, Andrade A, Kuritzkes DR, Lederman MM, Mehta NN. Treatment of HIV infection with a raltegravir-based regimen increases LDL levels, but improves HDL cholesterol efflux capacity. Antiviral Therapy. PMID 27740536 DOI: 10.3851/Imp3091  0.469
2016 Mudd JC, Panigrahi S, Kyi B, Moon SH, Manion MM, Younes SA, Sieg SF, Funderburg NT, Zidar DA, Lederman MM, Freeman ML. Inflammatory function of CX3CR1+ CD8 T cells in treated HIV infection is modulated by platelet interactions. The Journal of Infectious Diseases. PMID 27703039 DOI: 10.1093/Infdis/Jiw463  0.566
2016 Lederman MM, Cannon PM, Currier JS, June CH, Kiem HP, Kuritzkes DR, Lewin SR, Margolis DM, McCune JM, Mellors JW, Schacker TW, Sekaly RP, Tebas P, Walker BD, Douek DC. A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"? Pathogens & Immunity. 1: 154-164. PMID 27668293 DOI: 10.20411/pai.v1i1.133  0.424
2016 Freeman ML, Shive CL, Nguyen TP, Younes SA, Panigrahi S, Lederman MM. Cytokines and T-Cell Homeostasis in HIV Infection. The Journal of Infectious Diseases. 214: S51-7. PMID 27625431 DOI: 10.1093/Infdis/Jiw287  0.533
2016 Younes SA, Freeman ML, Mudd JC, Shive CL, Reynaldi A, Panigrahi S, Estes JD, Deleage C, Lucero C, Anderson J, Schacker TW, Davenport MP, McCune JM, Hunt PW, Lee SA, ... ... Lederman MM, et al. IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection. The Journal of Clinical Investigation. PMID 27322062 DOI: 10.1172/Jci85996  0.568
2016 Judge CJ, Sandberg JK, Funderburg NT, Sherman KE, Butt AA, Kang M, Landay AL, Lederman MM, Anthony DD. CD14brightCD16- monocytes and sCD14 level negatively associate with CD4-memory T-cell frequency and predict HCV-decline on therapy. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27258231 DOI: 10.1097/Qai.0000000000001104  0.401
2016 Nguyen TP, Shukla S, Asaad R, Freeman ML, Lederman MM, Harding CV, Sieg SF. Responsiveness to IL-7 but not to IFN-α is diminished in CD4 T cells from treated HIV infected patients who experience poor CD4 T cell recovery. Aids (London, England). PMID 27191978 DOI: 10.1097/Qad.0000000000001161  0.523
2016 Shmagel KV, Saidakova EV, Shmagel NG, Korolevskaya LB, Chereshnev VA, Robinson J, Grivel JC, Douek DC, Margolis L, Anthony DD, Lederman MM. Systemic inflammation and liver damage in HIV/hepatitis C virus coinfection. Hiv Medicine. PMID 27187749 DOI: 10.1111/Hiv.12357  0.428
2016 Musselwhite LW, Andrade BB, Ellenberg SS, Tierney A, Belaunzaran-Zamudio PF, Rupert A, Lederman MM, Sanne I, Sierra Madero JG, Sereti I. Vitamin D, d-dimer, Interferon γ, and sCD14 Levels are Independently Associated with Immune Reconstitution Inflammatory Syndrome: A Prospective, International Study. Ebiomedicine. 4: 115-23. PMID 26981576 DOI: 10.1016/J.Ebiom.2016.01.016  0.312
2016 Jacobson J, Bosinger S, Kang M, Belaunzaran-Zamudio P, Matining RM, Wilson C, Flexner CW, Clagett B, Plants J, Read S, Purdue L, Myers L, Boone L, Tebas P, Kumar P, ... ... Lederman MM, et al. The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1. Aids Research and Human Retroviruses. PMID 26935044 DOI: 10.1089/Aid.2015.0336  0.548
2016 Coiras M, Bermejo M, Descours B, Mateos E, García-Pérez J, López-Huertas MR, Lederman MM, Benkirane M, Alcamí J. IL-7 Induces SAMHD1 Phosphorylation in CD4+ T Lymphocytes, Improving Early Steps of HIV-1 Life Cycle. Cell Reports. 14: 2100-7. PMID 26923586 DOI: 10.1016/J.Celrep.2016.02.022  0.446
2016 Thiébaut R, Jarne A, Routy JP, Sereti I, Fischl M, Ive P, Speck RF, D'Offizi G, Casari S, Commenges D, Foulkes S, Natarajan V, Croughs T, Delfraissy JF, Tambussi G, ... ... Lederman MM, et al. Repeated Cycles of Recombinant Human Interleukin 7 in HIV-Infected Patients With Low CD4 T-Cell Reconstitution on Antiretroviral Therapy: Results of 2 Phase II Multicenter Studies. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 62: 1178-85. PMID 26908786 DOI: 10.1093/Cid/Ciw065  0.524
2016 Veazey RS, Pilch-Cooper HA, Hope TJ, Alter G, Carias AM, Sips M, Wang X, Rodriguez B, Sieg SF, Reich A, Wilkinson P, Cameron MJ, Lederman MM. Prevention of SHIV transmission by topical IFN-β treatment. Mucosal Immunology. PMID 26838048 DOI: 10.1038/Mi.2015.146  0.525
2016 Freeman ML, Lederman MM, Gianella S. Partners in Crime: The Role of CMV in Immune Dysregulation and Clinical Outcome During HIV Infection. Current Hiv/Aids Reports. 13: 10-9. PMID 26810437 DOI: 10.1007/S11904-016-0297-9  0.544
2015 Panigrahi S, Freeman ML, Funderburg NT, Mudd JC, Younes SA, Sieg SF, Zidar DA, Paiardini M, Villinger F, Calabrese LH, Ransohoff RM, Jain MK, Lederman MM. SIV/SHIV Infection Triggers Vascular Inflammation, Diminished Expression of Krüppel-like factor 2 (KLF2) and Endothelial Dysfunction. The Journal of Infectious Diseases. PMID 26671887 DOI: 10.1093/Infdis/Jiv749  0.429
2015 Zidar DA, Mudd JC, Juchnowski S, Lopes JP, Sparks S, Park SS, Ishikawa M, Osborne R, Washam JB, Chan C, Funderburg NT, Owoyele A, Alaiti MA, Mayuga M, Orringer C, ... ... Lederman MM, et al. Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26663396 DOI: 10.1161/Atvbaha.115.306112  0.337
2015 Shive CL, Clagett B, McCausland MR, Mudd JC, Funderburg NT, Freeman ML, Younes S, Ferrari BM, Rodriguez B, McComsey GA, Calabrese LH, Sieg SF, Lederman MM. Inflammation perturbs the IL-7 axis, promoting senescence and exhaustion that broadly characterize immune failure in treated HIV infection. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26627102 DOI: 10.1097/Qai.0000000000000913  0.448
2015 Li JZ, Etemad B, Ahmed H, Aga E, Bosch RJ, Mellors JW, Kuritzkes DR, Lederman MM, Para M, Gandhi RT. The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption. Aids (London, England). PMID 26588174 DOI: 10.1097/Qad.0000000000000953  0.466
2015 Kearney MF, Wiegand A, Shao W, Coffin JM, Mellors JW, Lederman M, Gandhi RT, Keele BF, Li JZ. Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses that are Transcriptionally Active Before Stopping Antiretroviral Therapy. Journal of Virology. PMID 26581989 DOI: 10.1128/Jvi.02139-15  0.475
2015 McCausland MR, Juchnowski SM, Zidar DA, Kuritzkes DR, Andrade A, Sieg SF, Lederman MM, Funderburg NT. Altered Monocyte Phenotype in HIV-1 Infection Tends to Normalize with Integrase-Inhibitor-Based Antiretroviral Therapy. Plos One. 10: e0139474. PMID 26430882 DOI: 10.1371/Journal.Pone.0139474  0.512
2015 Freeman ML, Mudd JC, Shive CL, Younes SA, Panigrahi S, Sieg SF, Lee SA, Hunt PW, Calabrese LH, Gianella S, Rodriguez B, Lederman MM. CD8 T cell expansion and inflammation linked to CMV co-infection in ART-treated HIV infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 26400999 DOI: 10.1093/Cid/Civ840  0.587
2015 Shive CL, Jiang W, Anthony DD, Lederman MM. Soluble CD14 is a nonspecific marker of monocyte activation. Aids (London, England). 29: 1263-5. PMID 26035325 DOI: 10.1097/Qad.0000000000000735  0.39
2015 Nguyen TP, Bazdar DA, Mudd JC, Lederman MM, Harding CV, Hardy GA, Sieg SF. Interferon-α inhibits CD4 T cell responses to interleukin-7 and interleukin-2 and selectively interferes with Akt signaling. Journal of Leukocyte Biology. 97: 1139-46. PMID 25784743 DOI: 10.1189/Jlb.4A0714-345Rr  0.345
2015 Vanpouille C, Lisco A, Grivel JC, Bassit LC, Kauffman RC, Sanchez J, Schinazi RF, Lederman MM, Rodriguez B, Margolis L. Valacyclovir Decreases Plasma HIV-1 RNA in HSV-2 Seronegative Individuals: A Randomized Placebo-Controlled Crossover Trial. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 60: 1708-14. PMID 25740794 DOI: 10.1093/Cid/Civ172  0.558
2015 Zidar DA, Juchnowski S, Ferrari B, Clagett B, Pilch-Cooper HA, Rose S, Rodriguez B, McComsey GA, Sieg SF, Mehta NN, Lederman MM, Funderburg NT. Oxidized LDL Levels Are Increased in HIV Infection and May Drive Monocyte Activation. Journal of Acquired Immune Deficiency Syndromes (1999). 69: 154-60. PMID 25647528 DOI: 10.1097/Qai.0000000000000566  0.564
2015 Shinha T, Mi D, Liu Z, Orschell CM, Lederman MM, Gupta SK. Relationships between renal parameters and serum and urine markers of inflammation in those with and without HIV infection. Aids Research and Human Retroviruses. 31: 375-83. PMID 25646974 DOI: 10.1089/Aid.2014.0234  0.52
2015 Hileman CO, Kinley B, Scharen-Guivel V, Melbourne K, Szwarcberg J, Robinson J, Lederman MM, Mccomsey GA. Differential Reduction in Monocyte Activation and Vascular Inflammation With Integrase Inhibitor-Based Initial Antiretroviral Therapy Among HIV-Infected Individuals. The Journal of Infectious Diseases. 212: 345-54. PMID 25583168 DOI: 10.1093/Infdis/Jiv004  0.551
2015 Lederman MM. A surprising role for TLR7. Nature Immunology. 16: 8-9. PMID 25521672 DOI: 10.1038/Ni.3051  0.421
2015 Funderburg NT, Jiang Y, Debanne SM, Labbato D, Juchnowski S, Ferrari B, Clagett B, Robinson J, Lederman MM, McComsey GA. Rosuvastatin reduces vascular inflammation and T-cell and monocyte activation in HIV-infected subjects on antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 68: 396-404. PMID 25514794 DOI: 10.1097/Qai.0000000000000478  0.559
2014 Sierra-Madero JG, Ellenberg SS, Rassool MS, Tierney A, Belaunzarán-Zamudio PF, López-Martínez A, Piñeirúa-Menéndez A, Montaner LJ, Azzoni L, Benítez CR, Sereti I, Andrade-Villanueva J, Mosqueda-Gómez JL, Rodriguez B, Sanne I, ... Lederman MM, et al. Effect of the CCR5 antagonist maraviroc on the occurrence of immune reconstitution inflammatory syndrome in HIV (CADIRIS): a double-blind, randomised, placebo-controlled trial. The Lancet. Hiv. 1: e60-7. PMID 26423989 DOI: 10.1016/S2352-3018(14)70027-X  0.452
2014 Sierra-Madero JG, Ellenberg S, Rassool MS, Tierney A, Belaunzarán-Zamudio PF, López-Martínez A, Piñeirúa-Menéndez A, Montaner LJ, Azzoni L, Benítez CR, Sereti I, Andrade-Villanueva J, Mosqueda-Gómez JL, Rodriguez B, Sanne I, ... Lederman MM, et al. A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Chemokine Receptor 5 (CCR5) Antagonist to Decrease the Occurrence of Immune Reconstitution Inflammatory Syndrome in HIV-Infection: The CADIRIS Study. The Lancet. Hiv. 1: e60-e67. PMID 26366430 DOI: 10.1016/S2352-3018(14)70027-X  0.401
2014 Li JZ, Heisey A, Ahmed H, Wang H, Zheng L, Carrington M, Wrin T, Schooley RT, Lederman MM, Kuritzkes DR. Relationship of HIV reservoir characteristics with immune status and viral rebound kinetics in an HIV therapeutic vaccine study. Aids (London, England). 28: 2649-57. PMID 25254301 DOI: 10.1097/Qad.0000000000000478  0.505
2014 Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, ... Lederman MM, et al. Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals. Plos Pathogens. 10: e1004345. PMID 25167059 DOI: 10.1371/Journal.Ppat.1004345  0.538
2014 Shmagel KV, Saidakova EV, Korolevskaya LB, Shmagel NG, Chereshnev VA, Anthony DD, Lederman MM. Influence of hepatitis C virus coinfection on CD4⁺ T cells of HIV-infected patients receiving HAART. Aids (London, England). 28: 2381-8. PMID 25111083 DOI: 10.1097/Qad.0000000000000418  0.502
2014 Zhang L, Luo Z, Sieg SF, Funderburg NT, Yu X, Fu P, Wu H, Jiao Y, Gao Y, Greenspan NS, Harding CV, Kilby JM, Li Z, Lederman MM, Jiang W. Plasmacytoid dendritic cells mediate synergistic effects of HIV and lipopolysaccharide on CD27+ IgD- memory B cell apoptosis. Journal of Virology. 88: 11430-41. PMID 25056888 DOI: 10.1128/Jvi.00682-14  0.538
2014 Mudd JC, Lederman MM. CD8 T cell persistence in treated HIV infection. Current Opinion in Hiv and Aids. 9: 500-5. PMID 25010897 DOI: 10.1097/Coh.0000000000000086  0.565
2014 Sandler NG, Zhang X, Bosch RJ, Funderburg NT, Choi AI, Robinson JK, Fine DM, Coombs RW, Jacobson JM, Landay AL, Douek DC, Tressler R, Read SW, Wilson CC, Deeks SG, ... Lederman MM, et al. Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection. The Journal of Infectious Diseases. 210: 1549-54. PMID 24864123 DOI: 10.1093/Infdis/Jiu305  0.479
2014 Thiébaut R, Drylewicz J, Prague M, Lacabaratz C, Beq S, Jarne A, Croughs T, Sekaly RP, Lederman MM, Sereti I, Commenges D, Lévy Y. Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection. Plos Computational Biology. 10: e1003630. PMID 24853554 DOI: 10.1371/Journal.Pcbi.1003630  0.529
2014 Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, et al. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. Plos Pathogens. 10: e1004078. PMID 24831517 DOI: 10.1371/Journal.Ppat.1004078  0.452
2014 Tenorio AR, Zheng Y, Bosch RJ, Krishnan S, Rodriguez B, Hunt PW, Plants J, Seth A, Wilson CC, Deeks SG, Lederman MM, Landay AL. Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment. The Journal of Infectious Diseases. 210: 1248-59. PMID 24795473 DOI: 10.1093/Infdis/Jiu254  0.508
2014 Funderburg NT, Lederman MM. Coagulation and morbidity in treated HIV infection. Thrombosis Research. 133: S21-4. PMID 24759134 DOI: 10.1016/J.Thromres.2014.03.012  0.542
2014 Hunt PW, Sinclair E, Rodriguez B, Shive C, Clagett B, Funderburg N, Robinson J, Huang Y, Epling L, Martin JN, Deeks SG, Meinert CL, Van Natta ML, Jabs DA, Lederman MM. Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection. The Journal of Infectious Diseases. 210: 1228-38. PMID 24755434 DOI: 10.1093/Infdis/Jiu238  0.534
2014 Longenecker CT, Jiang Y, Orringer CE, Gilkeson RC, Debanne S, Funderburg NT, Lederman MM, Storer N, Labbato DE, McComsey GA. Soluble CD14 is independently associated with coronary calcification and extent of subclinical vascular disease in treated HIV infection. Aids (London, England). 28: 969-77. PMID 24691204 DOI: 10.1097/Qad.0000000000000158  0.482
2014 Mukherjee PK, Chandra J, Retuerto M, Sikaroodi M, Brown RE, Jurevic R, Salata RA, Lederman MM, Gillevet PM, Ghannoum MA. Oral mycobiome analysis of HIV-infected patients: identification of Pichia as an antagonist of opportunistic fungi. Plos Pathogens. 10: e1003996. PMID 24626467 DOI: 10.1371/Journal.Ppat.1003996  0.486
2014 Olvera-García G, Espinosa E, Sieg SF, Lederman MM. Cytomegalovirus-specific responses of CD38⁺ memory T cells are skewed towards IFN-γ and dissociated from CD154 in HIV-1 infection. Aids (London, England). 28: 311-6. PMID 24594993 DOI: 10.1097/Qad.0000000000000162  0.533
2014 Shive CL, Mudd JC, Funderburg NT, Sieg SF, Kyi B, Bazdar DA, Mangioni D, Gori A, Jacobson JM, Brooks AD, Hardacre J, Ammori J, Estes JD, Schacker TW, Rodriguez B, ... Lederman MM, et al. Inflammatory cytokines drive CD4+ T-cell cycling and impaired responsiveness to interleukin 7: implications for immune failure in HIV disease. The Journal of Infectious Diseases. 210: 619-29. PMID 24585897 DOI: 10.1093/Infdis/Jiu125  0.558
2014 Lee SA, Sinclair E, Jain V, Huang Y, Epling L, Van Natta M, Meinert CL, Martin JN, McCune JM, Deeks SG, Lederman MM, Hecht FM, Hunt PW. Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection. The Journal of Infectious Diseases. 210: 374-82. PMID 24585893 DOI: 10.1093/Infdis/Jiu109  0.54
2014 Jiang W, Younes SA, Funderburg NT, Mudd JC, Espinosa E, Davenport MP, Babineau DC, Sieg SF, Lederman MM. Cycling memory CD4+ T cells in HIV disease have a diverse T cell receptor repertoire and a phenotype consistent with bystander activation. Journal of Virology. 88: 5369-80. PMID 24522925 DOI: 10.1128/Jvi.00017-14  0.513
2014 Sereti I, Estes JD, Thompson WL, Morcock DR, Fischl MA, Croughs T, Beq S, Lafaye de Micheaux S, Yao MD, Ober A, Wilson EM, Natarajan V, Imamichi H, Boulassel MR, Lederman MM, et al. Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration. Plos Pathogens. 10: e1003890. PMID 24497828 DOI: 10.1371/Journal.Ppat.1003890  0.53
2014 Funderburg NT, Jiang Y, Debanne SM, Storer N, Labbato D, Clagett B, Robinson J, Lederman MM, McComsey GA. Rosuvastatin treatment reduces markers of monocyte activation in HIV-infected subjects on antiretroviral therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: 588-95. PMID 24253250 DOI: 10.1093/Cid/Cit748  0.587
2014 Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM. Discordance between peripheral and colonic markers of inflammation during suppressive ART. Journal of Acquired Immune Deficiency Syndromes (1999). 65: 133-41. PMID 24121758 DOI: 10.1097/01.Qai.0000437172.08127.0B  0.499
2014 Shinha T, Mi D, Liu Z, Orschell C, Lederman M, Gupta S. 1612Intrarenal and Systemic Inflammation and HIV-related Renal Disease Open Forum Infectious Diseases. 1: S430-S430. DOI: 10.1093/Ofid/Ofu052.1158  0.413
2013 Funderburg NT, Andrade A, Chan ES, Rosenkranz SL, Lu D, Clagett B, Pilch-Cooper HA, Rodriguez B, Feinberg J, Daar E, Mellors J, Kuritzkes D, Jacobson JM, Lederman MM. Dynamics of immune reconstitution and activation markers in HIV+ treatment-naïve patients treated with raltegravir, tenofovir disoproxil fumarate and emtricitabine. Plos One. 8: e83514. PMID 24367599 DOI: 10.1371/Journal.Pone.0083514  0.542
2013 Hunt PW, Lederman MM, Deeks SG. Response: Maraviroc intensification and microbial translocation. Blood. 122: 2283-4. PMID 24072849 DOI: 10.1182/Blood-2013-08-516930  0.471
2013 Kalayjian RC, Spritzler J, Matining RM, Fiscus SA, Gross BH, Francis IR, Pollard RB, Lederman MM, Landay A. Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction. Aids (London, England). 27: 1563-71. PMID 24047762 DOI: 10.1097/Qad.0B013E32835Fabc2  0.564
2013 Longenecker CT, Jiang Y, Yun CH, Debanne S, Funderburg NT, Lederman MM, Storer N, Labbato DE, Bezerra HG, McComsey GA. Perivascular fat, inflammation, and cardiovascular risk in HIV-infected patients on antiretroviral therapy. International Journal of Cardiology. 168: 4039-45. PMID 23886531 DOI: 10.1016/J.Ijcard.2013.06.059  0.533
2013 Lederman MM, Funderburg NT, Sekaly RP, Klatt NR, Hunt PW. Residual immune dysregulation syndrome in treated HIV infection. Advances in Immunology. 119: 51-83. PMID 23886064 DOI: 10.1016/B978-0-12-407707-2.00002-3  0.581
2013 Wang NX, Sieg SF, Lederman MM, Offord RE, Hartley O, von Recum HA. Using glycosaminoglycan/chemokine interactions for the long-term delivery of 5P12-RANTES in HIV prevention. Molecular Pharmaceutics. 10: 3564-73. PMID 23859720 DOI: 10.1021/Mp3007242  0.307
2013 Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM. Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism. Science Translational Medicine. 5: 193ra91. PMID 23843452 DOI: 10.1126/Scitranslmed.3006438  0.552
2013 Andrade A, Rosenkranz SL, Cillo AR, Lu D, Daar ES, Jacobson JM, Lederman M, Acosta EP, Campbell T, Feinberg J, Flexner C, Mellors JW, Kuritzkes DR. Three distinct phases of HIV-1 RNA decay in treatment-naive patients receiving raltegravir-based antiretroviral therapy: ACTG A5248. The Journal of Infectious Diseases. 208: 884-91. PMID 23801609 DOI: 10.1093/Infdis/Jit272  0.424
2013 Funderburg NT, Stubblefield Park SR, Sung HC, Hardy G, Clagett B, Ignatz-Hoover J, Harding CV, Fu P, Katz JA, Lederman MM, Levine AD. Circulating CD4(+) and CD8(+) T cells are activated in inflammatory bowel disease and are associated with plasma markers of inflammation. Immunology. 140: 87-97. PMID 23600521 DOI: 10.1111/Imm.12114  0.391
2013 Taiwo B, Matining RM, Zheng L, Lederman MM, Rinaldo CR, Kim PS, Berzins BI, Kuritzkes DR, Jennings A, Eron JJ, Wilson CC. Associations of T cell activation and inflammatory biomarkers with virological response to darunavir/ritonavir plus raltegravir therapy. The Journal of Antimicrobial Chemotherapy. 68: 1857-61. PMID 23599363 DOI: 10.1093/Jac/Dkt120  0.461
2013 Vandergeeten C, Fromentin R, DaFonseca S, Lawani MB, Sereti I, Lederman MM, Ramgopal M, Routy JP, Sékaly RP, Chomont N. Interleukin-7 promotes HIV persistence during antiretroviral therapy. Blood. 121: 4321-9. PMID 23589672 DOI: 10.1182/Blood-2012-11-465625  0.582
2013 Hunt PW, Shulman NS, Hayes TL, Dahl V, Somsouk M, Funderburg NT, McLaughlin B, Landay AL, Adeyemi O, Gilman LE, Clagett B, Rodriguez B, Martin JN, Schacker TW, Shacklett BL, ... ... Lederman MM, et al. The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial. Blood. 121: 4635-46. PMID 23589670 DOI: 10.1182/Blood-2012-06-436345  0.552
2013 Schlatzer DM, Sugalski JM, Chen Y, Barnholtz-Sloan J, Davitkov P, Hazlett FE, Funderburg N, Rodriguez B, Lederman MM, Sieg SF, Chance MR, Anthony DD. Plasma proteome analysis reveals overlapping, yet distinct mechanisms of immune activation in chronic HCV and HIV infections. Journal of Acquired Immune Deficiency Syndromes (1999). 63: 563-71. PMID 23507661 DOI: 10.1097/Qai.0B013E3182909847  0.468
2013 Kalinowska M, Bazdar DA, Lederman MM, Funderburg N, Sieg SF. Decreased IL-7 responsiveness is related to oxidative stress in HIV disease. Plos One. 8: e58764. PMID 23505558 DOI: 10.1371/Journal.Pone.0058764  0.483
2013 Cubas RA, Mudd JC, Savoye AL, Perreau M, van Grevenynghe J, Metcalf T, Connick E, Meditz A, Freeman GJ, Abesada-Terk G, Jacobson JM, Brooks AD, Crotty S, Estes JD, Pantaleo G, ... Lederman MM, et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nature Medicine. 19: 494-9. PMID 23475201 DOI: 10.1038/Nm.3109  0.514
2013 Hardy GA, Sieg S, Rodriguez B, Anthony D, Asaad R, Jiang W, Mudd J, Schacker T, Funderburg NT, Pilch-Cooper HA, Debernardo R, Rabin RL, Lederman MM, Harding CV. Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers. Plos One. 8: e56527. PMID 23437155 DOI: 10.1371/Journal.Pone.0056527  0.551
2013 Mudd JC, Murphy P, Manion M, Debernardo R, Hardacre J, Ammori J, Hardy GA, Harding CV, Mahabaleshwar GH, Jain MK, Jacobson JM, Brooks AD, Lewis S, Schacker TW, Anderson J, ... ... Lederman MM, et al. Impaired T-cell responses to sphingosine-1-phosphate in HIV-1 infected lymph nodes. Blood. 121: 2914-22. PMID 23422746 DOI: 10.1182/Blood-2012-07-445783  0.54
2013 Longenecker CT, Funderburg NT, Jiang Y, Debanne S, Storer N, Labbato DE, Lederman MM, Mccomsey GA. Markers of inflammation and CD8 T-cell activation, but not monocyte activation, are associated with subclinical carotid artery disease in HIV-infected individuals Hiv Medicine. 14: 385-390. PMID 23332012 DOI: 10.1111/Hiv.12013  0.526
2013 Phillips E, Bartlett JA, Sanne I, Lederman MM, Hinkle J, Rousseau F, Dunn D, Pavlos R, James I, Mallal SA, Haas DW. Associations between HLA-DRB1*0102, HLA-B*5801, and hepatotoxicity during initiation of nevirapine-containing regimens in South Africa. Journal of Acquired Immune Deficiency Syndromes (1999). 62: e55-7. PMID 23328091 DOI: 10.1097/Qai.0B013E31827Ca50F  0.35
2013 Liang F, Bond E, Sandgren KJ, Smed-Sörensen A, Rangaka MX, Lange C, Koup RA, McComsey GA, Lederman MM, Wilkinson RJ, Andersson J, Loré K. Dendritic cell recruitment in response to skin antigen tests in HIV-1-infected individuals correlates with the level of T-cell infiltration. Aids (London, England). 27: 1071-80. PMID 23324660 DOI: 10.1097/Qad.0B013E32835Ecaca  0.501
2013 Klatt NR, Canary LA, Sun X, Vinton CL, Funderburg NT, Morcock DR, Quiñones M, Deming CB, Perkins M, Hazuda DJ, Miller MD, Lederman MM, Segre JA, Lifson JD, Haddad EK, et al. Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques. The Journal of Clinical Investigation. 123: 903-7. PMID 23321668 DOI: 10.1172/Jci66227  0.546
2012 Wang R, Bosch RJ, Benson CA, Lederman MM. Drug-resistant virus has reduced ability to induce immune activation. Journal of Acquired Immune Deficiency Syndromes (1999). 61: e60-3. PMID 23138731 DOI: 10.1097/Qai.0B013E31827171D7  0.52
2012 Funderburg NT, Zidar DA, Shive C, Lioi A, Mudd J, Musselwhite LW, Simon DI, Costa MA, Rodriguez B, Sieg SF, Lederman MM. Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome. Blood. 120: 4599-608. PMID 23065151 DOI: 10.1182/Blood-2012-05-433946  0.575
2012 Grant PM, Komarow L, Lederman MM, Pahwa S, Zolopa AR, Andersen J, Asmuth DM, Devaraj S, Pollard RB, Richterman A, Kanthikeel S, Sereti I. Elevated interleukin 8 and T-helper 1 and T-helper 17 cytokine levels prior to antiretroviral therapy in participants who developed immune reconstitution inflammatory syndrome during ACTG A5164. The Journal of Infectious Diseases. 206: 1715-23. PMID 23002445 DOI: 10.1093/Infdis/Jis604  0.482
2012 Lackner AA, Lederman MM, Rodriguez B. HIV pathogenesis: the host. Cold Spring Harbor Perspectives in Medicine. 2: a007005. PMID 22951442 DOI: 10.1101/Cshperspect.A007005  0.565
2012 Cimbro R, Vassena L, Arthos J, Cicala C, Kehrl JH, Park C, Sereti I, Lederman MM, Fauci AS, Lusso P. IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa. Blood. 120: 2610-9. PMID 22896005 DOI: 10.1182/Blood-2012-06-434779  0.323
2012 Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, Chun TW, Churchill M, Di Mascio M, Katlama C, Lafeuillade A, Landay A, Lederman M, Lewin SR, et al. Towards an HIV cure: a global scientific strategy. Nature Reviews. Immunology. 12: 607-14. PMID 22814509 DOI: 10.1038/Nri3262  0.506
2012 Anthony DD, Conry SJ, Medvik K, Sandhya Rani MR, Falck-Ytter Y, Blanton RE, Lederman MM, Rodriguez B, Landay AL, Sandberg JK. Baseline levels of soluble CD14 and CD16+56- natural killer cells are negatively associated with response to interferon/ribavirin therapy during HCV-HIV-1 coinfection. The Journal of Infectious Diseases. 206: 969-73. PMID 22782948 DOI: 10.1093/Infdis/Jis434  0.498
2012 Jiang W, Ghosh SK, Flyckt R, Kalinowska M, Starks D, Jurevic R, Weinberg A, Lederman MM, Rodriguez B. Bacterial colonization and beta defensins in the female genital tract in HIV infection. Current Hiv Research. 10: 504-12. PMID 22716110 DOI: 10.2174/157016212802429848  0.488
2012 Shive CL, Biancotto A, Funderburg NT, Pilch-Cooper HA, Valdez H, Margolis L, Sieg SF, McComsey GA, Rodriguez B, Lederman MM. HIV-1 is not a major driver of increased plasma IL-6 levels in chronic HIV-1 disease. Journal of Acquired Immune Deficiency Syndromes (1999). 61: 145-52. PMID 22659649 DOI: 10.1097/Qai.0B013E31825Ddbbf  0.492
2012 Lévy Y, Sereti I, Tambussi G, Routy JP, Lelièvre JD, Delfraissy JF, Molina JM, Fischl M, Goujard C, Rodriguez B, Rouzioux C, Avettand-Fenoël V, Croughs T, Beq S, Morre M, ... ... Lederman MM, et al. Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 55: 291-300. PMID 22550117 DOI: 10.1093/Cid/Cis383  0.58
2012 Li JZ, Brumme CJ, Lederman MM, Brumme ZL, Wang H, Spritzler J, Carrington M, Medvik K, Walker BD, Schooley RT, Kuritzkes DR. Characteristics and outcomes of initial virologic suppressors during analytic treatment interruption in a therapeutic HIV-1 gag vaccine trial. Plos One. 7: e34134. PMID 22479542 DOI: 10.1371/Journal.Pone.0034134  0.48
2012 Aghafar MZ, Witt C, Kamarulzaman A, Ismail R, Lederman MM, Rodriguez B, Senitzer D, Lee S, Price P. Genetic variations in loci relevant to natural killer cell function are affected by ethnicity but are generally not correlated with susceptibility to HIV-1. Tissue Antigens. 79: 367-71. PMID 22296096 DOI: 10.1111/J.1399-0039.2012.01843.X  0.47
2012 Manion M, Rodriguez B, Medvik K, Hardy G, Harding CV, Schooley RT, Pollard R, Asmuth D, Murphy R, Barker E, Brady KE, Landay A, Funderburg N, Sieg SF, Lederman MM. Interferon-alpha administration enhances CD8+ T cell activation in HIV infection. Plos One. 7: e30306. PMID 22291932 DOI: 10.1371/Journal.Pone.0030306  0.543
2012 Mayne E, Funderburg NT, Sieg SF, Asaad R, Kalinowska M, Rodriguez B, Schmaier AH, Stevens W, Lederman MM. Increased platelet and microparticle activation in HIV infection: upregulation of P-selectin and tissue factor expression. Journal of Acquired Immune Deficiency Syndromes (1999). 59: 340-6. PMID 22156911 DOI: 10.1097/Qai.0B013E3182439355  0.534
2012 Affandi JS, Aghafar ZK, Rodriguez B, Lederman MM, Burrows S, Senitzer D, Price P. Can immune-related genotypes illuminate the immunopathogenesis of cytomegalovirus disease in human immunodeficiency virus-infected patients? Human Immunology. 73: 168-74. PMID 22154842 DOI: 10.1016/J.Humimm.2011.11.005  0.469
2012 Gandhi RT, Coombs RW, Chan ES, Bosch RJ, Zheng L, Margolis DM, Read S, Kallungal B, Chang M, Goecker EA, Wiegand A, Kearney M, Jacobson JM, D'Aquila R, Lederman MM, et al. No effect of raltegravir intensification on viral replication markers in the blood of HIV-1-infected patients receiving antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 59: 229-35. PMID 22083073 DOI: 10.1097/Qai.0B013E31823Fd1F2  0.536
2011 Lederman MM, Calabrese L, Funderburg NT, Clagett B, Medvik K, Bonilla H, Gripshover B, Salata RA, Taege A, Lisgaris M, McComsey GA, Kirchner E, Baum J, Shive C, Asaad R, et al. Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells. The Journal of Infectious Diseases. 204: 1217-26. PMID 21917895 DOI: 10.1093/Infdis/Jir507  0.521
2011 Yonkers NL, Rodriguez B, Asaad R, Lederman MM, Anthony DD. Systemic immune activation in HIV infection is associated with decreased MDC responsiveness to TLR ligand and inability to activate naive CD4 T-cells. Plos One. 6: e23884. PMID 21912648 DOI: 10.1371/Journal.Pone.0023884  0.523
2011 Butler SL, Valdez H, Westby M, Perros M, June CH, Jacobson JM, Levy Y, Cooper DA, Douek D, Lederman MM, Tebas P. Disease-modifying therapeutic concepts for HIV in the era of highly active antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 58: 297-303. PMID 21792065 DOI: 10.1097/Qai.0B013E31822Ccfcc  0.517
2011 Mehlotra RK, Cheruvu VK, Blood Zikursh MJ, Benish RL, Lederman MM, Salata RA, Gripshover B, McComsey GA, Lisgaris MV, Fulton S, Subauste CS, Jurevic RJ, Guillemette C, Zimmerman PA, Rodriguez B. Chemokine (C-C motif) receptor 5 -2459 genotype in patients receiving highly active antiretroviral therapy: race-specific influence on virologic success. The Journal of Infectious Diseases. 204: 291-8. PMID 21673041 DOI: 10.1093/Infdis/Jir262  0.353
2011 Rodriguez B, Bazdar DA, Funderburg N, Asaad R, Luciano AA, Yadavalli G, Kalayjian RC, Lederman MM, Sieg SF. Frequencies of FoxP3+ naive T cells are related to both viral load and naive T cell proliferation responses in HIV disease. Journal of Leukocyte Biology. 90: 621-8. PMID 21653240 DOI: 10.1189/Jlb.1210661  0.558
2011 Vernon LT, Babineau DC, Demko CA, Lederman MM, Wang X, Toossi Z, Weinberg A, Rodriguez B. A prospective cohort study of periodontal disease measures and cardiovascular disease markers in HIV-infected adults. Aids Research and Human Retroviruses. 27: 1157-66. PMID 21443451 DOI: 10.1089/Aid.2010.0320  0.475
2011 Li JZ, Brumme ZL, Brumme CJ, Wang H, Spritzler J, Robertson MN, Lederman MM, Carrington M, Walker BD, Schooley RT, Kuritzkes DR. Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial. The Journal of Infectious Diseases. 203: 976-83. PMID 21402549 DOI: 10.1093/Infdis/Jiq143  0.543
2011 Anthony DD, Umbleja T, Aberg JA, Kang M, Medvik K, Lederman MM, Peters MG, Koziel MJ, Overton ET. Lower peripheral blood CD14+ monocyte frequency and higher CD34+ progenitor cell frequency are associated with HBV vaccine induced response in HIV infected individuals Vaccine. 29: 3558-3563. PMID 21397720 DOI: 10.1016/J.Vaccine.2011.02.092  0.416
2011 Jiang W, Lederman MM, Harding CV, Sieg SF. Presentation of soluble antigens to CD8+ T cells by CpG oligodeoxynucleotide-primed human naive B cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 2080-6. PMID 21239717 DOI: 10.4049/Jimmunol.1001869  0.384
2011 Crane HM, Grunfeld C, Willig JH, Mugavero MJ, Van Rompaey S, Moore R, Rodriguez B, Feldman BJ, Lederman MM, Saag MS, Kitahata MM. Impact of NRTIs on lipid levels among a large HIV-infected cohort initiating antiretroviral therapy in clinical care. Aids (London, England). 25: 185-95. PMID 21150555 DOI: 10.1097/Qad.0B013E328341F925  0.407
2011 Imamichi H, Degray G, Asmuth DM, Fischl MA, Landay AL, Lederman MM, Sereti I. HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy. Aids (London, England). 25: 159-64. PMID 21124203 DOI: 10.1097/Qad.0B013E328340A270  0.568
2011 Pilch-Cooper HA, Sieg SF, Hope TJ, Koons A, Escola JM, Offord R, Veazey RS, Mosier DE, Clagett B, Medvik K, Jadlowsky JK, Chance MR, Kiselar JG, Hoxie JA, Collman RG, ... ... Lederman MM, et al. Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5. Blood. 118: 1015-9. PMID 21068438 DOI: 10.1182/Blood-2010-05-282509  0.437
2011 Pilch-Cooper HA, Sieg SF, Hope TJ, Mercanti V, Offord R, Veazey RS, Mosier DE, Clagett B, Jadlowsky JK, Chance MR, Collman RG, Riddick NE, Hartley O, Lederman MM. Response: Absence of CCR5 intracellular pools in most CD4 and CD8 T cells Blood. 118: 1179. DOI: 10.1182/Blood-2011-05-350231  0.374
2010 Funderburg N, Kalinowska M, Eason J, Goodrich J, Heera J, Mayer H, Rajicic N, Valdez H, Lederman MM. Effects of maraviroc and efavirenz on markers of immune activation and inflammation and associations with CD4+ cell rises in HIV-infected patients. Plos One. 5: e13188. PMID 20949133 DOI: 10.1371/Journal.Pone.0013188  0.534
2010 Espinosa E, Ormsby CE, Reyes-Terán G, Asaad R, Sieg SF, Lederman MM. Dissociation of CD154 and cytokine expression patterns in CD38+ CD4+ memory T cells in chronic HIV-1 infection. Journal of Acquired Immune Deficiency Syndromes (1999). 55: 439-45. PMID 20926955 DOI: 10.1097/Qai.0B013E3181Ef991D  0.487
2010 Lederman MM, Alter G, Daskalakis DC, Rodriguez B, Sieg SF, Hardy G, Cho M, Anthony D, Harding C, Weinberg A, Silverman RH, Douek DC, Margolis L, Goldstein DB, Carrington M, et al. Determinants of protection among HIV‐exposed seronegative persons: an overview. The Journal of Infectious Diseases. 202: S333-8. PMID 20887220 DOI: 10.1086/655967  0.501
2010 Gandhi RT, Zheng L, Bosch RJ, Chan ES, Margolis DM, Read S, Kallungal B, Palmer S, Medvik K, Lederman MM, Alatrakchi N, Jacobson JM, Wiegand A, Kearney M, Coffin JM, et al. The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. Plos Medicine. 7. PMID 20711481 DOI: 10.1371/Journal.Pmed.1000321  0.521
2010 Lederman MM. Haemophilia, human immunodeficiency virus and human immunodeficiency virus pathogenesis. Thrombosis and Haemostasis. 104: 911-4. PMID 20694275 DOI: 10.1160/TH10-02-0096  0.48
2010 Schooley RT, Spritzler J, Wang H, Lederman MM, Havlir D, Kuritzkes DR, Pollard R, Battaglia C, Robertson M, Mehrotra D, Casimiro D, Cox K, Schock B. AIDS clinical trials group 5197: a placebo-controlled trial of immunization of HIV-1-infected persons with a replication-deficient adenovirus type 5 vaccine expressing the HIV-1 core protein. The Journal of Infectious Diseases. 202: 705-16. PMID 20662716 DOI: 10.1086/655468  0.522
2010 Macatangay BJ, Zheng L, Rinaldo CR, Landay AL, Pollard RB, Pahwa S, Lederman MM, Bucy RP. Comparison of immunologic assays for detecting immune responses in HIV immunotherapeutic studies: AIDS Clinical Trials Group Trial A5181. Clinical and Vaccine Immunology : Cvi. 17: 1452-9. PMID 20631337 DOI: 10.1128/Cvi.00498-09  0.503
2010 Grant PM, Komarow L, Andersen J, Sereti I, Pahwa S, Lederman MM, Eron J, Sanne I, Powderly W, Hogg E, Suckow C, Zolopa A. Risk factor analyses for immune reconstitution inflammatory syndrome in a randomized study of early vs. deferred ART during an opportunistic infection. Plos One. 5: e11416. PMID 20617176 DOI: 10.1371/Journal.Pone.0011416  0.535
2010 Cummins NW, Jiang W, McGinty J, Bren GD, Bosch RJ, Landay A, Deeks SG, Martin JN, Douek D, Lederman MM, Brenchley J, Badley AD. Intracellular Casp8p41 content is inversely associated with CD4 T cell count. The Journal of Infectious Diseases. 202: 386-91. PMID 20565257 DOI: 10.1086/653705  0.47
2010 Crawford KW, Spritzler J, Kalayjian RC, Parsons T, Landay A, Pollard R, Stocker V, Lederman MM, Flexner C. Age-related changes in plasma concentrations of the HIV protease inhibitor lopinavir. Aids Research and Human Retroviruses. 26: 635-43. PMID 20560793 DOI: 10.1089/Aid.2009.0154  0.434
2010 Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, Shin LY, Kovacs CM, Rodriguez B, Sieg SF, Teixeira-Johnson L, Gudonis D, Goepfert PA, Lederman MM, Frank I, Makedonas G, et al. Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. Plos Pathogens. 6: e1000917. PMID 20523897 DOI: 10.1371/Journal.Ppat.1000917  0.587
2010 Kalayjian RC, Machekano RN, Rizk N, Robbins GK, Gandhi RT, Rodriguez BA, Pollard RB, Lederman MM, Landay A. Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy. The Journal of Infectious Diseases. 201: 1796-805. PMID 20446847 DOI: 10.1086/652750  0.504
2010 Nedellec R, Coetzer M, Lederman MM, Offord RE, Hartley O, Mosier DE. "Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1 SF162 or simian-human immunodeficiency virus SHIV SF162-p3 do not confer resistance. Journal of Virology. 84: 5842-5. PMID 20335248 DOI: 10.1128/Jvi.01907-09  0.402
2010 Funderburg NT, Mayne E, Sieg SF, Asaad R, Jiang W, Kalinowska M, Luciano AA, Stevens W, Rodriguez B, Brenchley JM, Douek DC, Lederman MM. Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation. Blood. 115: 161-7. PMID 19828697 DOI: 10.1182/Blood-2009-03-210179  0.565
2010 Vernon LT, Demko CA, Whalen CC, Lederman MM, Toossi Z, Wu M, Han YW, Weinberg A. Erratum: Characterizing traditionally defined periodontal disease in HIV+ adults (Community Dentistry and Oral Epidemiology (2009) 37 (427-437)) Community Dentistry and Oral Epidemiology. 38. DOI: 10.1111/J.1600-0528.2009.00524.X  0.419
2009 Hulgan T, Donahue JP, Smeaton L, Pu M, Wang H, Lederman MM, Smith K, Valdez H, Pilcher C, Haas DW. Oral cyclosporin A inhibits CD4 T cell P-glycoprotein activity in HIV-infected adults initiating treatment with nucleoside reverse transcriptase inhibitors. European Journal of Clinical Pharmacology. 65: 1081-8. PMID 19779705 DOI: 10.1007/S00228-009-0725-5  0.48
2009 Conry SJ, Milkovich KA, Yonkers NL, Rodriguez B, Bernstein HB, Asaad R, Heinzel FP, Tary-Lehmann M, Lederman MM, Anthony DD. Impaired Plasmacytoid Dendritic Cell (PDC)-NK Cell Activity in Viremic Human Immunodeficiency Virus Infection Attributable to Impairments in both PDC and NK Cell Function Journal of Virology. 83: 11175-11187. PMID 19692459 DOI: 10.1128/Jvi.00753-09  0.458
2009 Vernon LT, Demko CA, Whalen CC, Lederman MM, Toossi Z, Wu M, Han YW, Weinberg A. Characterizing traditionally defined periodontal disease in HIV+ adults. Community Dentistry and Oral Epidemiology. 37: 427-37. PMID 19624697 DOI: 10.1111/J.1600-0528.2009.00485.X  0.456
2009 Mwanda WO, Orem J, Fu P, Banura C, Kakembo J, Onyango CA, Ness A, Reynolds S, Johnson JL, Subbiah V, Bako J, Wabinga H, Abdallah FK, Meyerson HJ, Whalen CC, ... Lederman MM, et al. Dose-modified oral chemotherapy in the treatment of AIDS-related non-Hodgkin's lymphoma in East Africa. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 3480-8. PMID 19470940 DOI: 10.1200/Jco.2008.18.7641  0.412
2009 Sereti I, Dunham RM, Spritzler J, Aga E, Proschan MA, Medvik K, Battaglia CA, Landay AL, Pahwa S, Fischl MA, Asmuth DM, Tenorio AR, Altman JD, Fox L, Moir S, ... ... Lederman MM, et al. IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection. Blood. 113: 6304-14. PMID 19380868 DOI: 10.1182/Blood-2008-10-186601  0.501
2009 Lederman MM, Este J. Targeting a host element as a strategy to block HIV replication: is it nice to fool with Mother Nature? Current Opinion in Hiv and Aids. 4: 79-81. PMID 19339944 DOI: 10.1097/COH.0b013e3283207b07  0.321
2009 Veazey RS, Ling B, Green LC, Ribka EP, Lifson JD, Piatak M, Lederman MM, Mosier D, Offord R, Hartley O. Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge. The Journal of Infectious Diseases. 199: 1525-7. PMID 19331577 DOI: 10.1086/598685  0.37
2009 Hardy GA, Sieg SF, Rodriguez B, Jiang W, Asaad R, Lederman MM, Harding CV. Desensitization to type I interferon in HIV-1 infection correlates with markers of immune activation and disease progression. Blood. 113: 5497-505. PMID 19299650 DOI: 10.1182/Blood-2008-11-190231  0.556
2009 Jiang W, Lederman MM, Hunt P, Sieg SF, Haley K, Rodriguez B, Landay A, Martin J, Sinclair E, Asher AI, Deeks SG, Douek DC, Brenchley JM. Plasma Levels of Bacterial DNA Correlate with Immune Activation and the Magnitude of Immune Restoration in Persons with Antiretroviral-Treated HIV Infection The Journal of Infectious Diseases. 199: 1177-1185. PMID 19265479 DOI: 10.1086/597476  0.583
2009 Tenorio AR, Spritzler J, Martinson J, Gichinga CN, Pollard RB, Lederman MM, Kalayjian RC, Landay AL. The effect of aging on T-regulatory cell frequency in HIV infection. Clinical Immunology. 130: 298-303. PMID 19008157 DOI: 10.1016/J.Clim.2008.10.001  0.537
2009 Hersperger AR, Pereyra F, Demers K, Sheth P, Shin LY, Rodriguez B, Sieg SF, Teixeira-Johnson L, Goepfert PA, Lederman MM, Kaul R, Makedonas G, Walker BD, Betts MR. S03-06 OA. Rapid perforin upregulation by CD8 T cells in elite controllers as a correlate of immune-mediated control of HIV replication Retrovirology. 6: O45. DOI: 10.1186/1742-4690-6-S3-O45  0.532
2008 Lederman MM, Jump R, Pilch-Cooper HA, Root M, Sieg SF. Topical application of entry inhibitors as "virustats" to prevent sexual transmission of HIV infection. Retrovirology. 5: 116-116. PMID 19094217 DOI: 10.1186/1742-4690-5-116  0.536
2008 Zapata W, Rodriguez B, Weber J, Estrada H, Quiñones-Mateu ME, Zimermman PA, Lederman MM, Rugeles MT. Increased levels of human beta-defensins mRNA in sexually HIV-1 exposed but uninfected individuals. Current Hiv Research. 6: 531-8. PMID 18991618 DOI: 10.2174/157016208786501463  0.486
2008 Cerini F, Landay A, Gichinga C, Lederman MM, Flyckt R, Starks D, Offord RE, Le Gal F, Hartley O. Chemokine analogues show suitable stability for development as microbicides. Journal of Acquired Immune Deficiency Syndromes (1999). 49: 472-6. PMID 18989226 DOI: 10.1097/Qai.0B013E31818C953F  0.415
2008 Lederman MM, Sereni D, Simonneau G, Voelkel NF. Pulmonary arterial hypertension and its association with HIV infection: an overview. Aids (London, England). 22: S1-6. PMID 18845916 DOI: 10.1097/01.Aids.0000327509.30385.3B  0.548
2008 Moonka D, Milkovich KA, Rodriguez B, Abouljoud M, Lederman MM, Anthony DD. Hepatitis C Virus-Specific T-Cell Gamma Interferon and Proliferative Responses Are More Common in Perihepatic Lymph Nodes than in Peripheral Blood or Liver Journal of Virology. 82: 11742-11748. PMID 18715927 DOI: 10.1128/Jvi.01130-08  0.341
2008 Grant RM, Hamer D, Hope T, Johnston R, Lange J, Lederman MM, Lieberman J, Miller CJ, Moore JP, Mosier DE, Richman DD, Schooley RT, Springer MS, Veazey RS, Wainberg MA. Whither or wither microbicides? Science (New York, N.Y.). 321: 532-4. PMID 18653884 DOI: 10.1126/Science.1160355  0.337
2008 Lederman MM, Margolis L. The lymph node in HIV pathogenesis. Seminars in Immunology. 20: 187-195. PMID 18620868 DOI: 10.1016/J.Smim.2008.06.001  0.478
2008 Jiang W, Lederman MM, Mohner RJ, Rodriguez B, Nedrich TM, Harding CV, Sieg SF. Impaired naive and memory B-cell responsiveness to TLR9 stimulation in human immunodeficiency virus infection. Journal of Virology. 82: 7837-45. PMID 18524824 DOI: 10.1128/Jvi.00660-08  0.52
2008 Funderburg N, Luciano AA, Jiang W, Rodriguez B, Sieg SF, Lederman MM. Toll-Like Receptor Ligands Induce Human T Cell Activation and Death, a Model for HIV Pathogenesis Plos One. 3. PMID 18382686 DOI: 10.1371/Journal.Pone.0001915  0.468
2008 Sieg SF, Bazdar DA, Lederman MM. S-phase entry leads to cell death in circulating T cells from HIV-infected persons. Journal of Leukocyte Biology. 83: 1382-1387. PMID 18372341 DOI: 10.1189/Jlb.0907643  0.454
2008 Lalezari J, Yadavalli GK, Para M, Richmond G, Dejesus E, Brown SJ, Cai W, Chen C, Zhong J, Novello LA, Lederman MM, Subramanian GM. Safety, pharmacokinetics, and antiviral activity of HGS004, a novel fully human IgG4 monoclonal antibody against CCR5, in HIV-1-infected patients. The Journal of Infectious Diseases. 197: 721-7. PMID 18266604 DOI: 10.1086/527327  0.459
2008 Kitahata MM, Rodriguez B, Haubrich R, Boswell S, Mathews WC, Lederman MM, Lober WB, Van Rompaey SE, Crane HM, Moore RD, Bertram M, Kahn JO, Saag MS. Cohort profile: the Centers for AIDS Research Network of Integrated Clinical Systems. International Journal of Epidemiology. 37: 948-55. PMID 18263650 DOI: 10.1093/Ije/Dym231  0.501
2007 Lederman MM, Penn-Nicholson A, Stone SF, Sieg SF, Rodriguez B. Monitoring clinical trials of therapeutic vaccines in HIV infection: role of treatment interruption. Current Opinion in Hiv and Aids. 2: 56-61. PMID 19372866 DOI: 10.1097/Coh.0B013E3280119264  0.434
2007 Lederman MM, Sieg SF. CCR5 and its ligands: a new axis of evil? Nature Immunology. 8: 1283-1285. PMID 18026077 DOI: 10.1038/Ni1207-1283  0.46
2007 Funderburg N, Lederman MM, Feng Z, Drage MG, Jadlowsky J, Harding CV, Weinberg A, Sieg SF. Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2. Proceedings of the National Academy of Sciences of the United States of America. 104: 18631-5. PMID 18006661 DOI: 10.1073/Pnas.0702130104  0.329
2007 Silvestri G, Paiardini M, Pandrea I, Lederman MM, Sodora DL. Understanding the benign nature of SIV infection in natural hosts. The Journal of Clinical Investigation. 117: 3148-54. PMID 17975656 DOI: 10.1172/Jci33034  0.55
2007 Luciano AA, Lederman MM, Valentin-Torres A, Bazdar DA, Sieg SF. Impaired Induction of CD27 and CD28 Predicts Naive CD4 T Cell Proliferation Defects in HIV Disease Journal of Immunology. 179: 3543-3549. PMID 17785788 DOI: 10.4049/Jimmunol.179.6.3543  0.513
2007 Lederman MM, Miller V, Weller I, Deeks SG. A new approach for 'deep salvage' trials in advanced HIV infection. Aids (London, England). 21: 1503-6. PMID 17630543 DOI: 10.1097/Qad.0B013E3281338384  0.452
2007 Jiang W, Lederman MM, Harding CV, Rodriguez B, Mohner RJ, Sieg SF. TLR9 stimulation drives naïve B cells to proliferate and to attain enhanced antigen presenting function. European Journal of Immunology. 37: 2205-13. PMID 17621369 DOI: 10.1002/Eji.200636984  0.338
2007 Rodriguez B, Valdez H, Mijch A, Watson K, Lederman MM, McComsey GA, Loupa CV, Woolley I. Statins Blunt HAART-Induced CD4 T-Cell Gains but Have No Long-Term Effect on Virologic Response to HAART. Journal of the International Association of Physicians in Aids Care (Jiapac). 6: 198-202. PMID 17579125 DOI: 10.1177/1545109707300684  0.563
2007 Mitsuyasu R, Gelman R, Cherng DW, Landay A, Fahey J, Reichman R, Erice A, Bucy RP, Kilby JM, Lederman MM, Hamilton CD, Lertora J, White BL, Tebas P, Duliege AM, et al. The virologic, immunologic, and clinical effects of interleukin 2 with potent antiretroviral therapy in patients with moderately advanced human immunodeficiency virus infection: a randomized controlled clinical trial--AIDS Clinical Trials Group 328. Archives of Internal Medicine. 167: 597-605. PMID 17389292 DOI: 10.1001/Archinte.167.6.597  0.438
2007 Yonkers NL, Rodriguez B, Milkovich KA, Asaad R, Lederman MM, Heeger PS, Anthony DD. TLR ligand-dependent activation of naive CD4 T cells by plasmacytoid dendritic cells is impaired in hepatitis C virus infection. Journal of Immunology (Baltimore, Md. : 1950). 178: 4436-44. PMID 17372001 DOI: 10.4049/Jimmunol.178.7.4436  0.407
2007 Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1 Blood. 109: 4272-4279. PMID 17289812 DOI: 10.1182/Blood-2006-11-055764  0.559
2007 Bosch RJ, Wang R, Vaida F, Lederman MM, Albrecht MA. Changes in the slope of the CD4 cell count increase after initiation of potent antiretroviral treatment. Journal of Acquired Immune Deficiency Syndromes (1999). 43: 433-5. PMID 17183628  0.379
2007 Dion ML, Bordi R, Zeidan J, Asaad R, Boulassel MR, Routy JP, Lederman MM, Sekaly RP, Cheynier R. Slow disease progression and robust therapy-mediated CD4+ T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection. Blood. 109: 2912-20. PMID 17164338 DOI: 10.1182/Blood-2006-09-047308  0.468
2007 Rodriguez B, Lederman MM, Sethi AK, Cheruvu VK, Bosch RJ, Martin J, Deeks S. Presenting Plasma HIV RNA Level and Rate of CD4 T-Cell Decline—Reply Jama. 297: 805-807. DOI: 10.1001/Jama.297.8.806  0.492
2006 Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, ... ... Lederman MM, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nature Medicine. 12: 1365-71. PMID 17115046 DOI: 10.1038/Nm1511  0.532
2006 Lederman MM, Smeaton L, Smith KY, Rodriguez B, Pu M, Wang H, Sevin A, Tebas P, Sieg SF, Medvik K, Margolis DM, Pollard R, Ertl HC, Valdez H. Cyclosporin A provides no sustained immunologic benefit to persons with chronic HIV-1 infection starting suppressive antiretroviral therapy: results of a randomized, controlled trial of the AIDS Clinical Trials Group A5138. The Journal of Infectious Diseases. 194: 1677-85. PMID 17109339 DOI: 10.1086/509261  0.535
2006 Benson CA, Vaida F, Havlir DV, Downey GF, Lederman MM, Gulick RM, Glesby MJ, Wantman M, Bixby CJ, Rinehart AR, Snyder S, Wang R, Patel S, Mellors JW. A randomized trial of treatment interruption before optimized antiretroviral therapy for persons with drug-resistant HIV: 48-week virologic results of ACTG A5086. The Journal of Infectious Diseases. 194: 1309-18. PMID 17041858 DOI: 10.1086/508289  0.443
2006 Rodríguez B, Sethi AK, Cheruvu VK, Mackay W, Bosch RJ, Kitahata M, Boswell SL, Mathews WC, Bangsberg DR, Martin J, Whalen CC, Sieg S, Yadavalli S, Deeks SG, Lederman MM. Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection. Jama. 296: 1498-506. PMID 17003398 DOI: 10.1001/Jama.296.12.1498  0.557
2006 Lederman MM, Penn-Nicholson A, Cho M, Mosier D. Biology of CCR5 and Its Role in HIV Infection and Treatment Jama. 296: 815-826. PMID 16905787 DOI: 10.1001/Jama.296.7.815  0.508
2006 Yonkers NL, Rodriguez B, Post AB, Asaad R, Jones L, Lederman MM, Lehmann PV, Anthony DD. HIV coinfection impairs CD28-mediated costimulation of hepatitis C virus-specific CD8 cells. The Journal of Infectious Diseases. 194: 391-400. PMID 16826489 DOI: 10.1086/505582  0.551
2006 Feng Z, Dubyak GR, Lederman MM, Weinberg A. Cutting edge: human beta defensin 3--a novel antagonist of the HIV-1 coreceptor CXCR4. Journal of Immunology (Baltimore, Md. : 1950). 177: 782-6. PMID 16818731 DOI: 10.4049/Jimmunol.177.2.782  0.433
2006 Rodriguez B, Lederman MM, Jiang W, Bazdar DA, Gàrate K, Harding CV, Sieg SF. Interferon-alpha differentially rescues CD4 and CD8 T cells from apoptosis in HIV infection. Aids (London, England). 20: 1379-89. PMID 16791012 DOI: 10.1097/01.Aids.0000233571.51899.Ab  0.502
2006 Lederman MM, Offord RE, Hartley O. Microbicides and other topical strategies to prevent vaginal transmission of HIV. Nature Reviews. Immunology. 6: 371-82. PMID 16639430 DOI: 10.1038/Nri1848  0.508
2006 Loupa CV, Rodriguez B, McComsey G, Gripshover B, Salata RA, Valdez H, Lisgaris MV, Fulton SA, Lederman MM. Gender differences in human immunodeficiency virus (HIV) RNA and CD4 cell counts among new entrants to HIV care. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 12: 389-91. PMID 16524417 DOI: 10.1111/J.1469-0691.2006.01368.X  0.512
2006 Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, Abraham J, Lederman MM, Benito JM, Goepfert PA, Connors M, Roederer M, Koup RA. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood. 107: 4781-9. PMID 16467198 DOI: 10.1182/Blood-2005-12-4818  0.573
2006 Kuekrek H, Schlingmann T, Valdez H, Boehm BO, Pollard RB, Mitsuyasu R, Goebel FD, Lederman MM, Lehmann PV, Tary-Lehmann M. Differential effect of interleukin-2 treatment on primary and secondary immunizations in HIV infected individuals. Aids (London, England). 19: 1967-74. PMID 16260902 DOI: 10.1097/01.Aids.0000189859.59559.9B  0.567
2005 Kalayjian RC, Spritzler J, Pu M, Landay A, Pollard RB, Stocker V, Harthi LA, Gross BH, Francis IR, Fiscus SA, Tebas P, Bosch RJ, Valcour V, Lederman MM. Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease. The Journal of Infectious Diseases. 192: 1577-87. PMID 16206072 DOI: 10.1086/466527  0.433
2005 Goedert JJ, Siegel J, Miller K, Lederman MM, Thompson A, Browning B, Gamerman S, McRedmond K, Withycombe J, Gruppo R, Stack G, Lusher J, Percy L, Nugent D, McDaniel M, et al. Prevalence of conditions associated with human immunodeficiency and hepatits virus infections among persons with haemophilia, 2001-2003 Haemophilia. 11: 516-528. PMID 16128897 DOI: 10.1111/J.1365-2516.2005.01138.X  0.498
2005 Loupa CV, Lederman MM, Valdez H, Salata RA, McComsey GA, Gripshover B, Fulton S, Lisgaris MV, Kucia M, Asaad R, Cline J, Rodríguez B. New entrants to HIV care are presenting only at marginally earlier stages of disease but may increasingly represent groups perceived at lower risk. Journal of the International Association of Physicians in Aids Care (Chicago, Ill. : 2002). 4: 47-51. PMID 16103026 DOI: 10.1177/1545109705278112  0.456
2005 Sieg SF, Rodriguez B, Asaad R, Jiang W, Bazdar DA, Lederman MM. Peripheral S-Phase T Cells in HIV Disease Have a Central Memory Phenotype and Rarely Have Evidence of Recent T Cell Receptor Engagement The Journal of Infectious Diseases. 192: 62-70. PMID 15942895 DOI: 10.1086/430620  0.564
2005 Baird HA, Marozsan AJ, Lederman MM, Landay A, Mildvan D, Kuritzkes DR, Kessler HA, Arts EJ. Monitoring processed, mature Human Immunodeficiency Virus type 1 particles immediately following treatment with a protease inhibitor-containing treatment regimen. Aids Research and Therapy. 2: 2. PMID 15826302 DOI: 10.1186/1742-6405-2-2  0.403
2005 Jiang W, Lederman MM, Salkowitz JR, Rodriguez B, Harding CV, Sieg SF. Impaired monocyte maturation in response to CpG oligodeoxynucleotide is related to viral RNA levels in human immunodeficiency virus disease and is at least partially mediated by deficiencies in alpha/beta interferon responsiveness and production. Journal of Virology. 79: 4109-19. PMID 15767412 DOI: 10.1128/Jvi.79.7.4109-4119.2005  0.525
2005 Sanne I, Mommeja-Marin H, Hinkle J, Bartlett JA, Lederman MM, Maartens G, Wakeford C, Shaw A, Quinn J, Gish RG, Rousseau F. Severe hepatotoxicity associated with nevirapine use in HIV-infected subjects. The Journal of Infectious Diseases. 191: 825-9. PMID 15717255 DOI: 10.1086/428093  0.475
2004 Mwanda O, Whalen C, Scot C, Lederman M, Orem J, Banura C. Anatomical site predilections of non-Hodgkin's lymphoma in Human Immunodeficiency Virus infection: A report on 54 cases East African Medical Journal. 81: 90-96. PMID 15622607 DOI: 10.4314/Eamj.V81I8.9212  0.337
2004 Martin MP, Lederman MM, Hutcheson HB, Goedert JJ, Nelson GW, van Kooyk Y, Detels R, Buchbinder S, Hoots K, Vlahov D, O'Brien SJ, Carrington M. Association of DC-SIGN promoter polymorphism with increased risk for parenteral, but not mucosal, acquisition of human immunodeficiency virus type 1 infection. Journal of Virology. 78: 14053-6. PMID 15564514 DOI: 10.1128/Jvi.78.24.14053-14056.2004  0.458
2004 Lederman MM, Veazey RS, Offord RE, Mosier DE, Dufour J, Mefford M, Piatak M, Lifson JD, Salkowitz JR, Rodriguez B, Blauvelt A, Hartley O. Prevention of Vaginal SHIV Transmission in Rhesus Macaques Through Inhibition of CCR5 Science. 306: 485-487. PMID 15486300 DOI: 10.1126/Science.1099288  0.469
2004 Hendrix CW, Collier AC, Lederman MM, Schols D, Pollard RB, Brown S, Jackson JB, Coombs RW, Glesby MJ, Flexner CW, Bridger GJ, Badel K, MacFarland RT, Henson GW, Calandra G, et al. Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection. Journal of Acquired Immune Deficiency Syndromes (1999). 37: 1253-62. PMID 15385732 DOI: 10.1097/01.Qai.0000137371.80695.Ef  0.489
2004 Smith K, Aga E, Bosch RJ, Valdez H, Connick E, Landay A, Kuritzkes D, Gross BH, Francis IR, McCune JM, Kessler H, Lederman M. Long-term changes in circulating CD4 T lymphocytes in virologically suppressed patients after 6 years of highly active antiretroviral therapy. Aids (London, England). 18: 1953-6. PMID 15353982 DOI: 10.1097/00002030-200409240-00012  0.47
2004 Ince MN, Harnisch B, Xu Z, Lee SK, Lange C, Moretta L, Lederman M, Lieberman J. Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function. Immunology. 112: 531-42. PMID 15270723 DOI: 10.1046/J.1365-2567.2004.01907.X  0.541
2004 Vogler MA, Teppler H, Gelman R, Valentine F, Lederman MM, Pomerantz RJ, Pollard RB, Cherng DW, Gonzalez CJ, Squires KE, Frank I, Mildvan D, Mahon LF, Schock B. Daily low-dose subcutaneous interleukin-2 added to single- or dual-nucleoside therapy in HIV infection does not protect against CD4+ T-cell decline or improve other indices of immune function: results of a randomized controlled clinical trial (ACTG 248). Journal of Acquired Immune Deficiency Syndromes (1999). 36: 576-87. PMID 15097300 DOI: 10.1097/00126334-200405010-00005  0.558
2004 Chakraborty B, Kiser P, Rangel HR, Weber J, Mirza M, Marotta ML, Asaad R, Rodriguez B, Valdez H, Lederman MM, Quiñones-Mateu ME. Can HIV-1 superinfection compromise antiretroviral therapy? Aids (London, England). 18: 132-4. PMID 15090842 DOI: 10.1097/00002030-200401020-00019  0.495
2004 Lange CG, Xu Z, Patterson BK, Medvik K, Harnisch B, Asaad R, Valdez H, Lee SJ, Landay A, Lieberman J, Lederman MM. Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function. Aids. 18: 605-613. PMID 15090765 DOI: 10.1097/00002030-200403050-00004  0.576
2004 Anthony DD, Yonkers NL, Post AB, Asaad R, Heinzel FP, Lederman MM, Lehmann PV, Valdez H. Selective impairments in dendritic cell-associated function distinguish hepatitis C virus and HIV infection. Journal of Immunology. 172: 4907-4916. PMID 15067070 DOI: 10.4049/Jimmunol.172.8.4907  0.464
2004 Salkowitz JR, Sieg SF, Harding CV, Lederman MM. In vitro human memory CD8 T cell expansion in response to cytomegalovirus requires CD4+ T cell help. The Journal of Infectious Diseases. 189: 971-83. PMID 14999599 DOI: 10.1086/382032  0.395
2004 Burton DR, Desrosiers RC, Doms RW, Feinberg MB, Gallo RC, Hahn B, Hoxie JA, Hunter E, Korber B, Landay A, Lederman MM, Lieberman J, McCune JM, Moore JP, Nathanson N, et al. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science (New York, N.Y.). 303: 316. PMID 14726576 DOI: 10.1126/Science.1094620  0.328
2003 Jacobson JM, Lederman MM, Spritzler J, Valdez H, Tebas P, Skowron G, Wang R, Jackson JB, Fox L, Landay A, Gilbert MJ, O'Neil D, Bancroft L, Al-Harthi L, Jacobson MA, et al. Granulocyte-macrophage colony-stimulating factor induces modest increases in plasma human immunodeficiency virus (HIV) type 1 RNA levels and CD4+ lymphocyte counts in patients with uncontrolled HIV infection. The Journal of Infectious Diseases. 188: 1804-14. PMID 14673758 DOI: 10.1086/379899  0.557
2003 Sieg SF, Bazdar DA, Lederman MM. Impaired TCR-mediated induction of Ki67 by naive CD4+ T cells is only occasionally corrected by exogenous IL-2 in HIV-1 infection. Journal of Immunology. 171: 5208-5214. PMID 14607921 DOI: 10.4049/Jimmunol.171.10.5208  0.54
2003 Haas DW, Wu H, Li H, Bosch RJ, Lederman MM, Kuritzkes D, Landay A, Connick E, Benson C, Wilkinson GR, Kessler H, Kim RB. MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study. Journal of Acquired Immune Deficiency Syndromes (1999). 34: 295-8. PMID 14600574 DOI: 10.1097/00126334-200311010-00006  0.485
2003 Quiñones-Mateu ME, Lederman MM, Feng Z, Chakraborty B, Weber J, Rangel HR, Marotta ML, Mirza M, Jiang B, Kiser P, Medvik K, Sieg SF, Weinberg A. Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication. Aids (London, England). 17: F39-48. PMID 14571200 DOI: 10.1097/00002030-200311070-00001  0.541
2003 Lange CG, Lederman MM, Medvik K, Asaad R, Wild M, Kalayjian R, Valdez H. Nadir CD4+ T-cell count and numbers of CD28+ CD4+ T-cells predict functional responses to immunizations in chronic HIV-1 infection. Aids (London, England). 17: 2015-23. PMID 14502004 DOI: 10.1097/00002030-200309260-00002  0.54
2003 Salkowitz JR, Bruse SE, Meyerson H, Valdez H, Mosier DE, Harding CV, Zimmerman PA, Lederman MM. CCR5 promoter polymorphism determines macrophage CCR5 density and magnitude of HIV-1 propagation in vitro. Clinical Immunology (Orlando, Fla.). 108: 234-40. PMID 14499246 DOI: 10.1016/S1521-6616(03)00147-5  0.45
2003 Rodriguez B, Valdez H, Freimuth W, Butler T, Asaad R, Lederman MM. Plasma levels of B-lymphocyte stimulator increase with HIV disease progression. Aids (London, England). 17: 1983-5. PMID 12960832 DOI: 10.1097/00002030-200309050-00018  0.555
2003 Hunt PW, Deeks SG, Rodriguez B, Valdez H, Shade SB, Abrams DI, Kitahata MM, Krone M, Neilands TB, Brand RJ, Lederman MM, Martin JN. Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy. Aids (London, England). 17: 1907-15. PMID 12960823 DOI: 10.1097/00002030-200309050-00009  0.585
2003 Wu H, Mellors J, Ruan P, McMahon D, Kelleher D, Lederman MM. Viral dynamics and their relations to baseline factors and longer term virologic responses in treatment-naive HIV-1-infected patients receiving abacavir in combination with HIV-1 protease inhibitors. Journal of Acquired Immune Deficiency Syndromes (1999). 33: 557-63. PMID 12902798 DOI: 10.1097/00126334-200308150-00002  0.513
2003 Weber J, Rangel HR, Chakraborty B, Marotta ML, Valdez H, Fransen K, Florence E, Connick E, Smith KY, Colebunders RL, Landay A, Kuritzkes DR, Lederman MM, Vanham G, Quiñones-Mateu ME. Role of Baseline pol Genotype in HIV-1 Fitness Evolution. Journal of Acquired Immune Deficiency Syndromes (1999). 33: 448-60. PMID 12869833 DOI: 10.1097/00126334-200308010-00005  0.484
2003 Diaz M, Douek DC, Valdez H, Hill BJ, Peterson D, Sanne I, Piliero PJ, Koup RA, Green SB, Schnittman S, Lederman MM. T cells containing T cell receptor excision circles are inversely related to HIV replication and are selectively and rapidly released into circulation with antiretroviral treatment. Aids (London, England). 17: 1145-9. PMID 12819515 DOI: 10.1097/00002030-200305230-00005  0.438
2003 Kawamura T, Gulden FO, Sugaya M, McNamara DT, Borris DL, Lederman MM, Orenstein JM, Zimmerman PA, Blauvelt A. R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms. Proceedings of the National Academy of Sciences of the United States of America. 100: 8401-6. PMID 12815099 DOI: 10.1073/Pnas.1432450100  0.549
2003 Kalayjian RC, Landay A, Pollard RB, Taub DD, Gross BH, Francis IR, Sevin A, Pu M, Spritzler J, Chernoff M, Namkung A, Fox L, Martinez A, Waterman K, Fiscus SA, ... ... Lederman MM, et al. Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes. The Journal of Infectious Diseases. 187: 1924-33. PMID 12792869 DOI: 10.1086/375372  0.544
2003 Wallis RS, Kalayjian R, Jacobson JM, Fox L, Purdue L, Shikuma CM, Arakaki R, Snyder S, Coombs RW, Bosch RJ, Spritzler J, Chernoff M, Aga E, Myers L, Schock B, ... Lederman MM, et al. A study of the immunology, virology, and safety of prednisone in HIV-1-infected subjects with CD4 cell counts of 200 to 700 mm(-3). Journal of Acquired Immune Deficiency Syndromes (1999). 32: 281-6. PMID 12626887 DOI: 10.1097/00126334-200303010-00006  0.511
2003 Valdez H, Mitsuyasu R, Landay A, Sevin AD, Chan ES, Spritzler J, Kalams SA, Pollard RB, Fahey J, Fox L, Namkung A, Estep S, Moss R, Sahner D, Lederman MM. Interleukin-2 Increases CD4+ lymphocyte numbers but does not enhance responses to immunization: results of A5046s. The Journal of Infectious Diseases. 187: 320-5. PMID 12552459 DOI: 10.1086/346056  0.499
2003 Rodriguez B, Woolley I, Lederman MM, Zdunek D, Hess G, Valdez H. Effect of GB Virus C Coinfection on Response to Antiretroviral Treatment in Human Immunodeficiency Virus–Infected Patients The Journal of Infectious Diseases. 187: 504-507. PMID 12552436 DOI: 10.1086/368206  0.501
2003 Lange CG, Lederman MM. Immune reconstitution with antiretroviral therapies in chronic HIV-1 infection Journal of Antimicrobial Chemotherapy. 51: 1-4. PMID 12493779 DOI: 10.1093/Jac/Dkg071  0.52
2003 Zhang D, Shankar P, Xu Z, Harnisch B, Chen G, Lange C, Lee SJ, Valdez H, Lederman MM, Lieberman J. Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic. Blood. 101: 226-35. PMID 12393740 DOI: 10.1182/Blood-2002-03-0791  0.594
2002 Southwell H, Valdez H, Lederman MM, Gripshover B. Use of alternative therapies among HIV-infected patients at an urban tertiary care center. Journal of Acquired Immune Deficiency Syndromes. 31: 119-120. PMID 12352160 DOI: 10.1097/00126334-200209010-00017  0.472
2002 Valdez H, Connick E, Smith KY, Lederman MM, Bosch RJ, Kim RS, St Clair M, Kuritzkes DR, Kessler H, Fox L, Blanchard-Vargas M, Landay A. Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease. Aids (London, England). 16: 1859-66. PMID 12351945 DOI: 10.1097/00002030-200209270-00002  0.548
2002 Goedert JJ, Eyster ME, Lederman MM, Mandalaki T, De Moerloose P, White GC, Angiolillo AL, Luban NL, Sherman KE, Manco-Johnson M, Preiss L, Leissinger C, Kessler CM, Cohen AR, DiMichele D, et al. End-stage liver disease in persons with hemophilia and transfusion-associated infections. Blood. 100: 1584-9. PMID 12176875  0.366
2002 Sha BE, Valdez H, Gelman RS, Landay AL, Agosti J, Mitsuyasu R, Pollard RB, Mildvan D, Namkung A, Ogata-Arakaki DM, Fox L, Estep S, Erice A, Kilgo P, Walker RE, ... ... Lederman MM, et al. Effect of etanercept (Enbrel) on interleukin 6, tumor necrosis factor alpha, and markers of immune activation in HIV-infected subjects receiving interleukin 2. Aids Research and Human Retroviruses. 18: 661-5. PMID 12079562 DOI: 10.1089/088922202760019365  0.351
2002 Lange CG, Lederman MM, Madero JS, Medvik K, Asaad R, Pacheko C, Carranza C, Valdez H. Impact of suppression of viral replication by highly active antiretroviral therapy on immune function and phenotype in chronic HIV-1 infection. Journal of Acquired Immune Deficiency Syndromes (1999). 30: 33-40. PMID 12048361 DOI: 10.1097/00042560-200205010-00005  0.556
2002 Otieno MW, Banura C, Katongole-Mbidde E, Johnson JL, Ghannoum M, Dowlati A, Renne R, Arts E, Whalen C, Lederman MM, Remick SC. Therapeutic challenges of AIDS-related non-Hodgkin's lymphoma in the United States and East Africa. Journal of the National Cancer Institute. 94: 718-32. PMID 12011222 DOI: 10.1093/Jnci/94.10.718  0.527
2002 Valdez H, Carlson NL, Post AB, Asaad R, Heeger PS, Lederman MM, Lehmann PV, Anthony DD. HIV long-term non-progressors maintain brisk CD8 T cell responses to other viral antigens. Aids (London, England). 16: 1113-8. PMID 12004269 DOI: 10.1097/00002030-200205240-00004  0.454
2002 Sieg SF, Mitchem JB, Bazdar DA, Lederman MM. Close Link between CD4+ and CD8+ T Cell Proliferation Defects in Patients with Human Immunodeficiency Virus Disease and Relationship to Extended Periods of CD4+ Lymphopenia The Journal of Infectious Diseases. 185: 1401-1408. PMID 11992274 DOI: 10.1086/340509  0.53
2002 Calabrese LH, Lederman MM, Spritzler J, Coombs RW, Fox L, Schock B, Yen-Lieberman B, Johnson R, Mildvan D, Parekh N. Placebo-controlled trial of cyclosporin-A in HIV-1 disease: implications for solid organ transplantation. Journal of Acquired Immune Deficiency Syndromes (1999). 29: 356-62. PMID 11917239 DOI: 10.1097/00126334-200204010-00005  0.566
2002 McComsey GA, Tan DJ, Lederman MM, Wilson E, Wong LJ. Analysis of the mitochondrial DNA genome in the peripheral blood leukocytes of HIV-infected patients with or without lipoatrophy. Aids. 16: 513-518. PMID 11872993 DOI: 10.1097/00002030-200203080-00001  0.464
2002 Lange CG, Valdez H, Medvik K, Asaad R, Lederman MM. CD4+ T-lymphocyte nadir and the effect of highly active antiretroviral therapy on phenotypic and functional immune restoration in HIV-1 infection. Clinical Immunology. 102: 154-161. PMID 11846457 DOI: 10.1006/Clim.2001.5164  0.543
2002 Lange CG, Gripshover BM, Valdez H, Lederman MM. Manifestation eines Hyper-IgE-Syndroms bei fortgeschrittener HIV-1-Infektion Medizinische Klinik. 97: 34-39. PMID 11831060 DOI: 10.1007/S00063-002-1122-3  0.524
2002 Wu H, Connick E, Kuritzkes DR, Landay A, Spritzler J, Zhang B, Spear GT, Kessler H, Lederman MM. Multiple CD4+ cell kinetic patterns and their relationships with baseline factors and virological responses in HIV type 1 patients receiving highly active antiretroviral therapy. Aids Research and Human Retroviruses. 17: 1231-40. PMID 11559422 DOI: 10.1089/088922201750461285  0.432
2002 Goedert JJ, Eyster ME, Lederman MM, Mandalaki T, Moerloose Pd, White GC, Angiolillo AL, Luban NLC, Sherman KE, Manco-Johnson M, Preiss L, Leissinger C, Kessler CM, Cohen AR, DiMichele D, et al. End-stage liver disease in persons with hemophilia and transfusion-associated infections. Blood. 100: 1584-1589. DOI: 10.1182/Blood.V100.5.1584.H81702001584_1584_1589  0.47
2001 Beinker NK, Mayers DL, Lange CG, Valdez H, Sitkins J, Lemonnier L, Chowdhry TK, Lederman MM. Genotypic drug resistance and cause of death in HIV-infected persons who died in 1999. Journal of Acquired Immune Deficiency Syndromes (1999). 28: 250-3. PMID 11694831 DOI: 10.1097/00042560-200111010-00007  0.5
2001 Teixeira L, Valdez H, McCune JM, Koup RA, Badley AD, Hellerstein MK, Napolitano LA, Douek DC, Mbisa G, Deeks S, Harris JM, Barbour JD, Gross BH, Francis IR, Halvorsen R, ... ... Lederman MM, et al. Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. Aids (London, England). 15: 1749-56. PMID 11579235 DOI: 10.1097/00002030-200109280-00002  0.585
2001 Sieg SF, Bazdar DA, Harding CV, Lederman MM. Differential expression of interleukin-2 and gamma interferon in human immunodeficiency virus disease. Journal of Virology. 75: 9983-5. PMID 11559831 DOI: 10.1128/Jvi.75.20.9983-9985.2001  0.497
2001 Sieg SF, Harding CV, Lederman MM. HIV-1 infection impairs cell cycle progression of CD4(+) T cells without affecting early activation responses. The Journal of Clinical Investigation. 108: 757-64. PMID 11544282 DOI: 10.1172/Jci12685  0.544
2001 Kruskall MS, Lee TH, Assmann SF, Laycock M, Kalish LA, Lederman MM, Busch MP. Survival of transfused donor white blood cells in HIV-infected recipients. Blood. 98: 272-279. PMID 11435293 DOI: 10.1182/Blood.V98.2.272  0.464
2001 Lederman MM. Immune restoration and CD4+ T-cell function with antiretroviral therapies. Aids. 15. PMID 11424971 DOI: 10.1097/00002030-200102002-00003  0.512
2001 Fry TJ, Connick E, Falloon J, Lederman MM, Liewehr DJ, Spritzler J, Steinberg SM, Wood LV, Yarchoan R, Zuckerman J, Landay A, Mackall CL. A potential role for interleukin-7 in T-cell homeostasis Blood. 97: 2983-2990. PMID 11342421 DOI: 10.1182/Blood.V97.10.2983  0.38
2001 Valdez H, Chowdhry TK, Asaad R, Woolley IJ, Davis T, Davidson R, Beinker N, Gripshover BM, Salata RA, McComsey G, Weissman SB, Lederman MM. Changing spectrum of mortality due to human immunodeficiency virus: analysis of 260 deaths during 1995--1999. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 32: 1487-93. PMID 11317251 DOI: 10.1086/320164  0.537
2001 Valdez H, Metcalf JA, Gripshover BM, Jacobson JM, Mitsuyasu R, Lederman MM. Effect of IL-2 therapy on plasma hepatitis C virus-RNA levels in HIV/hepatitis C virus co-infected patients [4] Aids. 15: 661-662. PMID 11317011 DOI: 10.1097/00002030-200103300-00023  0.423
2001 McComsey GA, Whalen CC, Mawhorter SD, Asaad R, Valdez H, Patki AH, Klaumunzner J, Gopalakrishna KV, Calabrese LH, Lederman MM. Placebo-controlled trial of prednisone in advanced HIV-1 infection Aids. 15: 321-327. PMID 11273211 DOI: 10.1097/00002030-200102160-00004  0.587
2001 Collier AC, Kalish LA, Busch MP, Gernsheimer T, Assmann SF, Lane TA, Asmuth DM, Lederman MM, Murphy EL, Kumar P, Kelley M, Flanigan TP, McMahon DK, Sacks HS, Kennedy MS, et al. Leukocyte-reduced red blood cell transfusions in patients with anemia and human immunodeficiency virus infection. The viral activation transfusion study: A randomized controlled trial Journal of the American Medical Association. 285: 1592-1601. PMID 11268267 DOI: 10.1001/Jama.285.12.1592  0.543
2001 Sollitto S, Mehlman M, Youngner S, Lederman MM. Should physicians withhold highly active antiretroviral therapies from HIV-AIDS patients who are thought to be poorly adherent to treatment? Aids. 15: 153-159. PMID 11216922 DOI: 10.1097/00002030-200101260-00003  0.479
2001 Salkowitz JR, Purvis SF, Meyerson H, Zimmerman P, O'Brien TR, Aledort L, Eyster ME, Hilgartner M, Kessler C, Konkle BA, White GC, Goedert JJ, Lederman MM. Characterization of high-risk HIV-1 seronegative hemophiliacs. Clinical Immunology (Orlando, Fla.). 98: 200-11. PMID 11161976 DOI: 10.1006/Clim.2000.4969  0.537
2001 Havlir DV, Torriani FJ, Schrier RD, Huang JY, Lederman MM, Chervenak KA, Boom WH. Serum Interleukin-6 (IL-6), IL-10, Tumor Necrosis Factor (TNF) Alpha, Soluble Type II TNF Receptor, and Transforming Growth Factor Beta Levels in Human Immunodeficiency Virus Type 1-Infected Individuals with Mycobacterium avium Complex Disease Journal of Clinical Microbiology. 39: 298-303. PMID 11136787 DOI: 10.1128/Jcm.39.1.298-303.2001  0.391
2001 Lederman M, Mosier D, Arts E, Letvin N, Flexner C, Blauvelt A, Cairns S, Bridges S, Sarver N, Offord R. Rationale for testing chemokine inhibitors (Virustats) for prevention of HIV-1 transmission. Aids. 15: S57-S58. DOI: 10.1097/00002030-200102001-00081  0.466
2000 Lederman MM, McKinnis R, Kelleher D, Cutrell A, Mellors J, Neisler M, Cooney E, Haas DW, Haubrich R, Stanford J, Horton J, Landay A, Spreen W. Cellular restoration in HIV infected persons treated with abacavir and a protease inhibitor: age inversely predicts naive CD4 cell count increase. Aids (London, England). 14: 2635-42. PMID 11125881 DOI: 10.1097/00002030-200012010-00002  0.551
2000 Picchio GR, Valdez H, Sabbe R, Landay AL, Kuritzkes DR, Lederman MM, Mosier DE. Altered viral fitness of HIV-1 following failure of protease inhibitor-based therapy. Journal of Acquired Immune Deficiency Syndromes. 25: 289-295. PMID 11114828 DOI: 10.1097/00042560-200012010-00001  0.522
2000 Patki AH, Zielske SP, Sieg SF, Lederman MM. Preferential S phase entry and apoptosis of CD4+ T lymphocytes of HIV-1-infected patients after in vitro cultivation Clinical Immunology. 97: 241-247. PMID 11112363 DOI: 10.1006/Clim.2000.4940  0.53
2000 Valdez H, Anthony D, Farukhi F, Patki A, Salkowitz J, Heeger P, Peterson DL, Post AB, Asaad R, Lederman MM. Immune responses to hepatitis C and non-hepatitis C antigens in hepatitis C virus infected and HIV-1 coinfected patients. Aids (London, England). 14: 2239-46. PMID 11089611 DOI: 10.1097/00002030-200010200-00004  0.436
2000 Lederman MM, Valdez H. Immune restoration with antiretroviral therapies: implications for clinical management. Jama. 284: 223-228. PMID 10889597 DOI: 10.1001/Jama.284.2.223  0.549
2000 Lederman MM, Kalish LA, Asmuth D, Fiebig E, Mileno M, Busch MP. 'Modeling' relationships among HIV-1 replication, immune activation and CD4+ T-cell losses using adjusted correlative analyses Aids. 14: 951-958. PMID 10853976 DOI: 10.1097/00002030-200005260-00006  0.557
2000 MacArthur RD, Lederman MM, Benson CA, Chernoff MC, MacGregor RR, Spritzler J, Mahon LF, Yen-Lieberman B, Purvis S. Effects of Mycobacterium avium complex-infection treatment on cytokine expression in human immunodeficiency virus-infected persons: results of AIDS clinical trials group protocol 853. The Journal of Infectious Diseases. 181: 1486-90. PMID 10762582 DOI: 10.1086/315370  0.46
2000 Benson CA, Williams PL, Cohn DL, Becker S, Hojczyk P, Nevin T, Korvick JA, Heifets L, Child CC, Lederman MM, Reichman RC, Powderly WG, Notario GF, Wynne BA, Hafner R. Clarithromycin or rifabutin alone or in combination for primary prophylaxis of Mycobacterium avium complex disease in patients with AIDS: A randomized, double-blind, placebo-controlled trial. The AIDS Clinical Trials Group 196/Terry Beirn Community Programs for Clinical Research on AIDS 009 Protocol Team. The Journal of Infectious Diseases. 181: 1289-97. PMID 10762562 DOI: 10.1086/315380  0.318
2000 Valdez H, Smith KY, Landay A, Connick E, Kuritzkes DR, Kessler H, Fox L, Spritzler J, Roe J, Lederman MB, Lederman HM, Evans TG, Heath-Chiozzi M, Lederman MM. Response to immunization with recall and neoantigens after prolonged administration of an HIV-1 protease inhibitor-containing regimen Aids. 14: 11-21. PMID 10714563 DOI: 10.1097/00002030-200001070-00002  0.459
2000 Kuritzkes DR, Sevin A, Young B, Bakhtiari M, Wu H, St Clair M, Connick E, Landay A, Spritzler J, Kessler H, Lederman MM. Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine-lamivudine-ritonavir: genotypic analysis of human immunodeficiency virus type 1 isolates from AIDS clinical trials group protocol 315.ACTG Protocol 315 Team. The Journal of Infectious Diseases. 181: 491-7. PMID 10669331 DOI: 10.1086/315244  0.44
2000 Connick E, Lederman MM, Kotzin BL, Spritzler J, Kuritzkes DR, St Clair M, Sevin AD, Fox L, Chiozzi MH, Leonard JM, Rousseau F, D'Arc Roe J, Martinez A, Kessler H, Landay A. Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic response. The Journal of Infectious Diseases. 181: 358-63. PMID 10608789 DOI: 10.1086/315171  0.544
2000 Smith KY, Valdez H, Landay A, Spritzler J, Kessler HA, Connick E, Kuritzkes D, Gross B, Francis I, McCune JM, Lederman MM. Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy Journal of Infectious Diseases. 181: 141-147. PMID 10608760 DOI: 10.1086/315169  0.57
1999 Woolley I, Valdez H, Walker C, Davidson R, Zdunek D, Hess G, Lederman MM. GBV-C/HGV infection in HIV-infected patients. Clinical Microbiology and Infection. 5: 236-237. PMID 11856260 DOI: 10.1111/J.1469-0691.1999.Tb00134.X  0.492
1999 Patki AH, Purvis SF, Meyerson HJ, Lederman MM. Lymphocyte proliferation assays may underestimate antigen responsiveness in human immunodeficiency virus infection. Clinical Immunology. 93: 245-249. PMID 10600335 DOI: 10.1006/Clim.1999.4802  0.487
1999 Chien JW, Valdez H, McComsey G, McClernon D, St Clair M, Lederman MM. Presence of mutation conferring resistance to lamivudine in plasma and cerebrospinal fluid of HIV-1-infected patients. Journal of Acquired Immune Deficiency Syndromes (1999). 21: 277-80. PMID 10428105 DOI: 10.1097/00126334-199908010-00004  0.457
1999 Patki AH, Purvis SF, Valdez H, Spritzler J, Connick E, Kuritzkes DR, Kessler H, Fox L, St Clair M, Landay A, Lederman MM. HIV infection perturbs DNA content of lymphoid cells: partial correction after 'suppression' of virus replication. Aids (London, England). 13: 1177-85. PMID 10416520 DOI: 10.1097/00002030-199907090-00005  0.521
1999 Kaushal S, Landay AL, Lederman MM, Connick E, Spritzler J, Kuritzkes DR, Kessler H, Levine BL, St Louis DC, June CH. Increases in T cell telomere length in HIV infection after antiretroviral combination therapy for HIV-1 infection implicate distinct population dynamics in CD4+ and CD8+ T cells. Clinical Immunology (Orlando, Fla.). 92: 14-24. PMID 10413649 DOI: 10.1006/Clim.1999.4726  0.507
1999 Shapiro HM, Lederman M, Connick E, Kessler H, Kuritzkes DR, Landay AL. Small differences in CD4+ T-cell production may go unnoticed. Aids (London, England). 13: 290-1. PMID 10202843 DOI: 10.1097/00002030-199902040-00025  0.358
1999 Aziz N, Nishanian P, Taylor JM, Mitsuyasu RT, Jacobson JM, Dezube BJ, Lederman MM, Detels R, Fahey JL. Stability of plasma levels of cytokines and soluble activation markers in patients with human immunodeficiency virus infection. The Journal of Infectious Diseases. 179: 843-8. PMID 10068579 DOI: 10.1086/314673  0.497
1999 Wu H, Kuritzkes DR, McClernon DR, Kessler H, Connick E, Landay A, Spear G, Heath-Chiozzi M, Rousseau F, Fox L, Spritzler J, Leonard JM, Lederman MM. Characterization of viral dynamics in human immunodeficiency virus type 1-infected patients treated with combination antiretroviral therapy: relationships to host factors, cellular restoration, and virologic end points. The Journal of Infectious Diseases. 179: 799-807. PMID 10068574 DOI: 10.1086/314670  0.491
1999 Valdez H, Purvis S, Asaad R, Valerio I, Sha BE, Landay AL, Lederman MM. Levels of Proinflammatory Cytokines in Plasma after Pneumoccoccal Immunization in Human Immunodeficiency Virus Type 1-Infected Patients Clinical and Vaccine Immunology. 6: 427-428. DOI: 10.1128/Cdli.6.3.427-428.1999  0.431
1998 Quiñones-Mateu ME, Mas A, Lera TLd, Soriano V, Alcamı́ J, Lederman MM, Domingo E. LTR and tat variability of HIV-1 isolates from patients with divergent rates of disease progression Virus Research. 57: 11-20. PMID 9833881 DOI: 10.1016/S0168-1702(98)00082-3  0.46
1998 Powderly WG, Landay A, Lederman MM. Recovery of the immune system with antiretroviral therapy: the end of opportunism? Jama. 280: 72-77. PMID 9660367 DOI: 10.1001/Jama.280.1.72  0.557
1998 Lederman MM, Connick E, Landay A, Kuritzkes DR, Spritzler J, St Clair M, Kotzin BL, Fox L, Chiozzi MH, Leonard JM, Rousseau F, Wade M, Roe JD, Martinez A, Kessler H. Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315. The Journal of Infectious Diseases. 178: 70-9. PMID 9652425 DOI: 10.1086/515591  0.557
1998 Badley AD, Dockrell DH, Algeciras A, Ziesmer S, Landay A, Lederman MM, Connick E, Kessler H, Kuritzkes D, Lynch DH, Roche P, Yagita H, Paya CV. In vivo analysis of Fas/FasL interactions in HIV-infected patients. The Journal of Clinical Investigation. 102: 79-87. PMID 9649560 DOI: 10.1172/Jci2691  0.547
1998 Haas DW, Lederman MM, Clough LA, Wallis RS, Chernoff D, Crampton SL. Proinflammatory cytokine and human immunodeficiency virus RNA levels during early Mycobacterium avium complex bacteremia in advanced AIDS. The Journal of Infectious Diseases. 177: 1746-9. PMID 9607863 DOI: 10.1086/517437  0.366
1998 Barditch-Crovo P, Noe D, Skowron G, Lederman M, Kalayjian RC, Borum P, Buier R, Rowe WB, Goldberg D, Lietman P. A phase I/II evaluation of oral L-2-oxothiazolidine-4-carboxylic acid in asymptomatic patients infected with human immunodeficiency virus. Journal of Clinical Pharmacology. 38: 357-63. PMID 9590463 DOI: 10.1002/J.1552-4604.1998.Tb04435.X  0.391
1998 Valdez H, Al-Harthi L, Landay A, Lederman MM. Rationale for immune-based therapies for HIV-1 infection. The Journal of Laboratory and Clinical Medicine. 131: 197-206. PMID 9523842 DOI: 10.1016/S0022-2143(98)90090-7  0.524
1998 Lederman MM, Valdez H. Cytotoxic T-Cell Activity and Progression of HIV Disease Jama. 279: 242-242. PMID 9438750 DOI: 10.1001/Jama.279.3.242  0.561
1998 Wallis RS, Lederman HM, Spritzler J, Devers JL, Georges D, Weinberg A, Stehn S, Lederman MM, Bucy RP, Craiu A, Dinarello C, Fahey J, Fletcher M, Mizrachi Y, Reuben JM, et al. Measurement of induced cytokines in AIDS clinical trials using whole blood: A preliminary report Clinical and Vaccine Immunology. 5: 556-560. DOI: 10.1128/Cdli.5.4.556-560.1998  0.31
1997 Goedert JJ, Erdman DD, Konkle BA, Török TJ, Lederman MM, Kleinert D, Mandalaki T, Kessler CM, Anderson LJ, Luban NLC. Parvovirus B19 quiescence during the course of human immunodeficiency virus infection in persons with hemophilia American Journal of Hematology. 56: 248-251. PMID 9395187 DOI: 10.1002/(Sici)1096-8652(199712)56:4<248::Aid-Ajh9>3.0.Co;2-X  0.473
1997 Dezube BJ, Lederman MM, Chapman B, Georges DL, Dogon AL, Mudido P, Reis-Lishing J, Cheng SL, Silberman SL, Crumpacker CS. The Effect of Tenidap on Cytokines, Acute-Phase Proteins, and Virus Load in Human Immunodeficiency Virus (HIV)-Infected Patients: Correlation between Plasma HIV-1 RNA and Proinflammatory Cytokine Levels The Journal of Infectious Diseases. 176: 807-810. PMID 9291340 DOI: 10.1086/517308  0.523
1997 Chervenak KA, Lederman MM, Boom WH. Bacterial Antigen Activation of Vδ1 and Vδ2 γδ T Cells of Persons Infected with Human Immunodeficiency Virus Type 1 The Journal of Infectious Diseases. 175: 429-433. PMID 9203665 DOI: 10.1093/Infdis/175.2.429  0.569
1997 Patki AH, Georges DL, Lederman MM. CD4+-T-cell counts, spontaneous apoptosis, and Fas expression in peripheral blood mononuclear cells obtained from human immunodeficiency virus type 1-infected subjects. Clinical and Vaccine Immunology. 4: 736-741. DOI: 10.1128/Cdli.4.6.736-741.1997  0.495
1996 Hammer SM, Katzenstein DA, Hughes MD, Gundacker H, Schooley RT, Haubrich RH, Henry WK, Lederman MM, Phair JP, Niu M, Hirsch MS, Merigan TC. A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. AIDS Clinical Trials Group Study 175 Study Team. The New England Journal of Medicine. 335: 1081-90. PMID 8813038 DOI: 10.1056/Nejm199610103351501  0.516
1996 Patki AH, Quiñones-Mateu ME, Dorazio D, Yen-Lieberman B, Boom WH, Thomas EK, Lederman MM. Activation of antigen-induced lymphocyte proliferation by interleukin-15 without the mitogenic effect of interleukin-2 that may induce human immunodeficiency virus-1 expression. The Journal of Clinical Investigation. 98: 616-21. PMID 8698851 DOI: 10.1172/Jci118831  0.505
1996 Patki AH, Lederman MM. HIV-1 Tat Protein and Its Inhibitor Ro 24-7429 Inhibit Lymphocyte Proliferation and Induce Apoptosis in Peripheral Blood Mononuclear Cells from Healthy Donors Cellular Immunology. 169: 40-46. PMID 8612292 DOI: 10.1006/Cimm.1996.0088  0.51
1995 Dezube BJ, Lederman MM. Pentoxifylline for the treatment of HIV infection and its complications. Journal of Cardiovascular Pharmacology. 25. PMID 8699854 DOI: 10.1097/00005344-199500252-00029  0.53
1995 Lederman MM. Host-directed and immune-based therapies for human immunodeficiency virus infection. Annals of Internal Medicine. 122: 218-222. PMID 7810941 DOI: 10.7326/0003-4819-122-3-199502010-00010  0.447
1995 Lederman MM, Jackson JB, Kroner BL, White GC, Eyster ME, Aledort LM, Hilgartner MW, Kessler CM, Cohen AR, Kiger KP. Human immunodeficiency virus (HIV) type 1 infection status and in vitro susceptibility to HIV infection among high-risk HIV-1-seronegative hemophiliacs. The Journal of Infectious Diseases. 172: 228-31. PMID 7797917 DOI: 10.1093/Infdis/172.1.228  0.546
1995 Dezube BJ, Lederman MM, Spritzler JG, Chapman B, Korvick JA, Flexner C, Dando S, Mattiacci MR, Ahlers CM, Zhang L, Novick WJ, Kasdan P, Fahey JL, Pardee AB, Crumpacker CS. High-dose pentoxifylline in patients with AIDS: Inhibition of tumor necrosis factor production Journal of Infectious Diseases. 171: 1628-1632. PMID 7769305 DOI: 10.1093/Infdis/171.6.1628  0.423
1995 Haubrich RH, Flexner C, Lederman MM, Hirsch M, Pettinelli CP, Ginsberg R, Lietman P, Hamzeh FM, Spector SA, Richman DD, Hammer S, Cooley T, Gulick R, Sullivan M, Spina C, et al. A randomized trial of the activity and safety of ro 24-7429 (tat antagonist) versus nucleoside for human immunodeficiency virus infection Journal of Infectious Diseases. 172: 1246-1252. PMID 7594660 DOI: 10.1093/Infdis/172.5.1246  0.48
1995 Lederman MM, Georges D, Dando S, Schmelzer R, Averill L, Goldberg D. L-2-oxothiazolidine-4-carboxylic acid (procysteine) inhibits expression of the human immunodeficiency virus and expression of the interleukin-2 receptor alpha chain. Journal of Acquired Immune Deficiency Syndromes. 8: 107-115. DOI: 10.1097/00042560-199502000-00001  0.467
1994 Lederman MM, Kroner B, Kiger K, Goedert JJ. Pneumonia and pneumococcal immunization in human immunodeficiency virus-seropositive hemophiliacs. Blood. 83: 2005-2005. DOI: 10.1182/Blood.V83.7.2005A.Bloodjournal8372005A  0.335
1992 Lederman MM, Sprague L, Wallis RS, Ellner JJ. Duration of fever during treatment of infective endocarditis. Medicine. 71: 52-7. PMID 1549059 DOI: 10.1097/00005792-199201000-00005  0.323
1992 Purvis SF, Georges DL, Williams TM, Lederman MM. Suppression of interleukin-2 and interleukin-2 receptor expression in Jurkat cells stably expressing the human immunodeficiency virus Tat protein. Cellular Immunology. 144: 32-42. PMID 1394441 DOI: 10.1016/0008-8749(92)90223-C  0.398
1992 Rabkin CS, Hilgartner MW, Hedberg KW, Aledort LM, Hatzakis A, Eichinger S, Eyster ME, White GC, Kessler CM, Lederman MM, Moerloose Pd, Bray GL, Cohen AR, Andes WA, Manco-Johnson M, et al. Incidence of lymphomas and other cancers in HIV-infected and HIV-uninfected patients with hemophilia. Jama. 267: 1090-1094. DOI: 10.1001/Jama.1992.03480080060027  0.531
1991 Lederman MM, Mehlman MJ. Physicians Infected With HIV Jama. 265: 2337-2338. DOI: 10.1001/Jama.1991.03460180043022  0.524
1990 Aucott JN, Fayen J, Grossnicklas H, Morrissey A, Lederman MM, Salata RA. Invasive infection with Saccharomyces cerevisiae: report of three cases and review. Reviews of Infectious Diseases. 12: 406-11. PMID 2193348 DOI: 10.1093/Clinids/12.3.406  0.322
1989 Wiest PM, Flanigan T, Salata RA, Shlaes DM, Katzman M, Lederman MM. Serious infectious complications of corticosteroid therapy for COPD Chest. 95: 1180-1184. PMID 2721249 DOI: 10.1378/Chest.95.6.1180  0.302
1989 Lederman MM, Purvis SF, Walter EI, Carey JT, Medof ME. Heightened complement sensitivity of acquired immunodeficiency syndrome lymphocytes related to diminished expression of decay-accelerating factor Proceedings of the National Academy of Sciences of the United States of America. 86: 4205-4209. PMID 2471198 DOI: 10.1073/Pnas.86.11.4205  0.397
1987 Katzman M, Carey JT, Elmets CA, Jacobs GH, Lederman MM. Molluscum contagiosum and the acquired immunodeficiency syndrome: Clinical and immunological details of two cases British Journal of Dermatology. 116: 131-138. PMID 3814509 DOI: 10.1111/J.1365-2133.1987.Tb05801.X  0.361
1987 Carey JT, Lederman MM. Treatment of AIDS With Transfer Factor Jama: the Journal of the American Medical Association. 258: 3515-3516. PMID 3682152 DOI: 10.1001/Jama.1987.03400240047018  0.371
1987 Wiest PM, Wiese K, Jacobs MR, Morrissey AB, Abelson TI, Witt W, Lederman MM. Alternaria infection in a patient with acquired immunodeficiency syndrome: case report and review of invasive alternaria infections. Reviews of Infectious Diseases. 9: 799-803. PMID 3326127 DOI: 10.1093/Clinids/9.4.799  0.358
1987 Lederman MM, Carey JT, Schacter B, Aucott J, Ellner JJ. Lymphocytes of persons with the acquired immunodeficiency syndrome and related conditions express reactivity with the monoclonal antibody 4D12 reflective of in vivo lymphocyte activation Human Immunology. 20: 279-291. PMID 3125134 DOI: 10.1016/0198-8859(87)90019-X  0.323
1987 Salata RA, Lederman MM, Shlaes DM, Jacobs MR, Eckstein E, Tweardy D, Toossi Z, Chmielewski R, Marino J, King CH. Diagnosis of nosocomial pneumonia in intubated, intensive care unit patients. The American Review of Respiratory Disease. 135: 426-432. PMID 3101559 DOI: 10.1164/Arrd.1987.135.2.426  0.31
1987 Carey JT, Lederman MM, Toossi Z, Edmonds K, Hodder S, Calabrese LH, Proffitt MR, Johnson CE, Ellner JJ. Augmentation of Skin Test Reactivity and Lymphocyte Blastogenesis in Patients With AIDS Treated With Transfer Factor Jama: the Journal of the American Medical Association. 257: 651-655. DOI: 10.1001/Jama.1987.03390050077022  0.315
1986 Wieland M, Lederman MM, Kline-King C, Keys TF, Lerner PI, Bass SN, Chemilewski R, Banks VD, Ellner JJ. Left-sided endocarditis due to Pseudomonas aeruginosa. A report of 10 cases and review of the literature. Medicine. 65: 180-189. PMID 3084905 DOI: 10.1097/00005792-198605000-00006  0.307
1986 Katzman M, Lederman MM. Defective postbinding lysis underlies the impaired natural killer activity in factor VIII-treated, human T lymphotropic virus type III seropositive hemophiliacs. The Journal of Clinical Investigation. 77: 1057-62. PMID 3007575 DOI: 10.1172/Jci112404  0.316
1986 Berk GI, Lederman MM, Liebman ML, Ellner JJ. Staphylococcal protein A primed leukocytes enhance the autologous mixed lymphocyte reaction American Journal of the Medical Sciences. 291: 255-263. PMID 2939717 DOI: 10.1097/00000441-198604000-00007  0.323
1985 Katzman M, Elmets CA, Lederman MM. Molluscum contagiosum and the acquired immunodeficiency syndrome. Annals of Internal Medicine. 102: 413-4. PMID 3970488 DOI: 10.7326/0003-4819-102-3-413_3  0.333
1983 Lederman MM, Ratnoff OD, Scillian JJ, Jones PK, Schacter B. Impaired cell-mediated immunity in patients with classic hemophilia New England Journal of Medicine. 308: 79-83. PMID 6216408 DOI: 10.1056/Nejm198301133080205  0.351
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