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Hakon Hakonarson, M.D., PhD - Publications

Children’s Hospital of Philadelphia / University of Pennsylvania, Philadelphia, PA, United States 

186 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Li YR, Glessner JT, Coe BP, Li J, Mohebnasab M, Chang X, Connolly J, Kao C, Wei Z, Bradfield J, Kim C, Hou C, Khan M, Mentch F, Qiu H, ... ... Hakonarson H, et al. Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations. Nature Communications. 11: 255. PMID 31937769 DOI: 10.1038/s41467-019-13624-1  0.44
2017 Chang X, Zhao Y, Hou C, Glessner J, McDaniel L, Diamond MA, Thomas K, Li J, Wei Z, Liu Y, Guo Y, Mentch FD, Qiu H, Kim C, Evans P, ... ... Hakonarson H, et al. Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk. Nature Communications. 8: 569. PMID 28924153 DOI: 10.1038/s41467-017-00408-8  0.44
2016 Li D, Bhoj E, McCormick E, Wang F, Snyder J, Wang T, Zhao Y, Kim C, Chiavacci R, Tian L, Falk MJ, Hakonarson H. Early Infantile Epileptic Encephalopathy in an STXBP1 Patient with Lactic Acidemia and Normal Mitochondrial Respiratory Chain Function. Case Reports in Genetics. 2016: 4140780. PMID 27069701 DOI: 10.1155/2016/4140780  0.44
2016 Cofer ZC, Cui S, EauClaire SF, Kim C, Tobias JW, Hakonarson H, Loomes KM, Matthews RP. Methylation Microarray Studies Highlight PDGFA Expression as a Factor in Biliary Atresia. Plos One. 11: e0151521. PMID 27010479 DOI: 10.1371/journal.pone.0151521  0.44
2016 Desai A, Connolly JJ, March M, Hou C, Chiavacci R, Kim C, Lyon G, Hadley D, Hakonarson H. Systematic data-querying of large pediatric biorepository identifies novel Ehlers-Danlos Syndrome variant. Bmc Musculoskeletal Disorders. 17: 80. PMID 26879370 DOI: 10.1186/s12891-016-0936-8  1
2016 Guo Y, Wei Z, Keating BJ, Hakonarson H. Machine learning derived risk prediction of anorexia nervosa. Bmc Medical Genomics. 9: 4. PMID 26792494 DOI: 10.1186/s12920-016-0165-x  1
2016 Wenger TL, Kao C, McDonald-McGinn DM, Zackai EH, Bailey A, Schultz RT, Morrow BE, Emanuel BS, Hakonarson H. The Role of mGluR Copy Number Variation in Genetic and Environmental Forms of Syndromic Autism Spectrum Disorder. Scientific Reports. 6: 19372. PMID 26781481 DOI: 10.1038/srep19372  1
2015 Chang X, Glessner J, Tin A, Li J, Guo Y, Wei Z, Liu Y, Mentch FD, Hou C, Zhao Y, Wang T, Qiu H, Kim C, Sleiman PM, Hakonarson H. Genome-wide association study reveals two loci for serum magnesium concentrations in European-American children. Scientific Reports. 5: 18792. PMID 26685716 DOI: 10.1038/srep18792  1
2015 De R, Verma SS, Drenos F, Holzinger ER, Holmes MV, Hall MA, Crosslin DR, Carrell DS, Hakonarson H, Jarvik G, Larson E, Pacheco JA, Rasmussen-Torvik LJ, Moore CB, Asselbergs FW, et al. Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR). Biodata Mining. 8: 41. PMID 26674805 DOI: 10.1186/s13040-015-0074-0  1
2015 Li YR, Zhao SD, Li J, Bradfield JP, Mohebnasab M, Steel L, Kobie J, Abrams DJ, Mentch FD, Glessner JT, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, ... ... Hakonarson H, et al. Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nature Communications. 6: 8442. PMID 26450413 DOI: 10.1038/ncomms9442  1
2015 Li J, Fung I, Glessner JT, Pandey R, Wei Z, Bakay M, Mentch FD, Pellegrino R, Wang T, Kim C, Hou C, Wang F, Chiavacci RM, Thomas KA, Spergel JM, ... Hakonarson H, et al. Copy Number Variations in CTNNA3 and RBFOX1 Associate with Pediatric Food Allergy. Journal of Immunology (Baltimore, Md. : 1950). PMID 26188062 DOI: 10.4049/jimmunol.1402310  0.44
2015 Bhoj EJ, Li D, Harr MH, Tian L, Wang T, Zhao Y, Qiu H, Kim C, Hoffman JD, Hakonarson H, Zackai EH. Expanding the SPECC1L mutation phenotypic spectrum to include Teebi hypertelorism syndrome. American Journal of Medical Genetics. Part A. PMID 26111080 DOI: 10.1002/ajmg.a.37217  1
2015 Satterthwaite TD, Vandekar SN, Wolf DH, Bassett DS, Ruparel K, Shehzad Z, Craddock RC, Shinohara RT, Moore TM, Gennatas ED, Jackson C, Roalf DR, Milham MP, Calkins ME, Hakonarson H, et al. Connectome-wide network analysis of youth with Psychosis-Spectrum symptoms. Molecular Psychiatry. PMID 26033240 DOI: 10.1038/mp.2015.66  1
2015 Lill CM, Rengmark A, Pihlstrøm L, Fogh I, Shatunov A, Sleiman PM, Wang LS, Liu T, Lassen CF, Meissner E, Alexopoulos P, Calvo A, Chio A, Dizdar N, Faltraco F, ... ... Hakonarson H, et al. The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25936935 DOI: 10.1016/j.jalz.2014.12.009  1
2015 Rodriguez S, Gaunt TR, Guo Y, Zheng J, Barnes MR, Tang W, Danish F, Johnson A, Castillo BA, Li YR, Hakonarson H, Buxbaum SG, Palmer T, Tsai MY, Lange LA, et al. Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array. European Journal of Human Genetics : Ejhg. PMID 25920552 DOI: 10.1038/ejhg.2015.63  1
2015 Brehm JM, Ramratnam SK, Tse SM, Croteau-Chonka DC, Pino-Yanes M, Rosas-Salazar C, Litonjua AA, Raby BA, Boutaoui N, Han YY, Chen W, Forno E, Marsland AL, Nugent NR, Eng C, ... ... Hakonarson H, et al. Stress and Bronchodilator Response in Children with Asthma. American Journal of Respiratory and Critical Care Medicine. 192: 47-56. PMID 25918834 DOI: 10.1164/rccm.201501-0037OC  1
2015 Li J, Jørgensen SF, Maggadottir SM, Bakay M, Warnatz K, Glessner J, Pandey R, Salzer U, Schmidt RE, Perez E, Resnick E, Goldacker S, Buchta M, Witte T, Padyukov L, ... ... Hakonarson H, et al. Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells. Nature Communications. 6: 6804. PMID 25891430 DOI: 10.1038/ncomms7804  1
2015 Chang X, Li J, Guo Y, Wei Z, Mentch FD, Hou C, Zhao Y, Qiu H, Kim C, Sleiman PM, Hakonarson H. Genome-wide association study of serum minerals levels in children of different ethnic background. Plos One. 10: e0123499. PMID 25886283 DOI: 10.1371/journal.pone.0123499  0.44
2015 Calkins ME, Merikangas KR, Moore TM, Burstein M, Behr MA, Satterthwaite TD, Ruparel K, Wolf DH, Roalf DR, Mentch FD, Qiu H, Chiavacci R, Connolly JJ, Sleiman PM, Gur RC, ... Hakonarson H, et al. The Philadelphia Neurodevelopmental Cohort: constructing a deep phenotyping collaborative. Journal of Child Psychology and Psychiatry, and Allied Disciplines. PMID 25858255 DOI: 10.1111/jcpp.12416  1
2015 Wolf DH, Satterthwaite TD, Calkins ME, Ruparel K, Elliott MA, Hopson RD, Jackson CT, Prabhakaran K, Bilker WB, Hakonarson H, Gur RC, Gur RE. Functional neuroimaging abnormalities in youth with psychosis spectrum symptoms. Jama Psychiatry. 72: 456-65. PMID 25785510 DOI: 10.1001/jamapsychiatry.2014.3169  1
2015 Nead KT, Li A, Wehner MR, Neupane B, Gustafsson S, Butterworth A, Engert JC, Davis AD, Hegele RA, Miller R, den Hoed M, Khaw KT, Kilpeläinen TO, Wareham N, Edwards TL, ... ... Hakonarson H, et al. Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals. Human Molecular Genetics. 24: 3582-94. PMID 25784503 DOI: 10.1093/hmg/ddv097  1
2015 Merikangas KR, Calkins ME, Burstein M, He JP, Chiavacci R, Lateef T, Ruparel K, Gur RC, Lehner T, Hakonarson H, Gur RE. Comorbidity of physical and mental disorders in the neurodevelopmental genomics cohort study. Pediatrics. 135: e927-38. PMID 25755242 DOI: 10.1542/peds.2014-1444  1
2015 Maggadottir SM, Li J, Glessner JT, Li YR, Wei Z, Chang X, Mentch FD, Thomas KA, Kim CE, Zhao Y, Hou C, Wang F, Jørgensen SF, Perez EE, Sullivan KE, ... ... Hakonarson H, et al. Rare variants at 16p11.2 are associated with common variable immunodeficiency. The Journal of Allergy and Clinical Immunology. 135: 1569-77. PMID 25678086 DOI: 10.1016/j.jaci.2014.12.1939  1
2015 Gil-Rodríguez MC, Deardorff MA, Ansari M, Tan CA, Parenti I, Baquero-Montoya C, Ousager LB, Puisac B, Hernández-Marcos M, Teresa-Rodrigo ME, Marcos-Alcalde I, Wesselink JJ, Lusa-Bernal S, Bijlsma EK, Braunholz D, ... ... Hakonarson H, et al. De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes. Human Mutation. 36: 454-62. PMID 25655089 DOI: 10.1002/humu.22761  1
2015 Roy SM, Chesi A, Mentch F, Xiao R, Chiavacci R, Mitchell JA, Kelly A, Hakonarson H, Grant SF, Zemel BS, McCormack SE. Body mass index (BMI) trajectories in infancy differ by population ancestry and may presage disparities in early childhood obesity. The Journal of Clinical Endocrinology and Metabolism. 100: 1551-60. PMID 25636051 DOI: 10.1210/jc.2014-4028  1
2015 Guo Y, Menezes MJ, Menezes MP, Liang J, Li D, Riley LG, Clarke NF, Andrews PI, Tian L, Webster R, Wang F, Liu X, Shen Y, Thorburn DR, Keating BJ, ... ... Hakonarson H, et al. Delayed diagnosis of congenital myasthenia due to associated mitochondrial enzyme defect. Neuromuscular Disorders : Nmd. 25: 257-61. PMID 25557462 DOI: 10.1016/j.nmd.2014.11.017  1
2015 Menezes MJ, Guo Y, Zhang J, Riley LG, Cooper ST, Thorburn DR, Li J, Dong D, Li Z, Glessner J, Davis RL, Sue CM, Alexander SI, Arbuckle S, Kirwan P, ... ... Hakonarson H, et al. Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia. Human Molecular Genetics. 24: 2297-307. PMID 25556185 DOI: 10.1093/hmg/ddu747  1
2015 Falk MJ, Shen L, Gonzalez M, Leipzig J, Lott MT, Stassen AP, Diroma MA, Navarro-Gomez D, Yeske P, Bai R, Boles RG, Brilhante V, Ralph D, DaRe JT, Shelton R, et al. Mitochondrial Disease Sequence Data Resource (MSeqDR): a global grass-roots consortium to facilitate deposition, curation, annotation, and integrated analysis of genomic data for the mitochondrial disease clinical and research communities. Molecular Genetics and Metabolism. 114: 388-96. PMID 25542617 DOI: 10.1016/j.ymgme.2014.11.016  1
2015 St Pourcain B, Haworth CM, Davis OS, Wang K, Timpson NJ, Evans DM, Kemp JP, Ronald A, Price T, Meaburn E, Ring SM, Golding J, Hakonarson H, Plomin R, Davey Smith G. Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence. Human Genetics. 134: 539-51. PMID 25515860 DOI: 10.1007/s00439-014-1514-5  1
2015 Sgariglia F, Pedrini E, Bradfield JP, Bhatti TR, D'Adamo P, Dormans JP, Gunawardena AT, Hakonarson H, Hecht JT, Sangiorgi L, Pacifici M, Enomoto-Iwamoto M, Grant SF. The type 2 diabetes associated rs7903146 T allele within TCF7L2 is significantly under-represented in Hereditary Multiple Exostoses: insights into pathogenesis. Bone. 72: 123-7. PMID 25498973 DOI: 10.1016/j.bone.2014.11.024  1
2015 Ellis JA, Scurrah KJ, Li YR, Ponsonby AL, Chavez RA, Pezic A, Dwyer T, Akikusa JD, Allen RC, Becker ML, Thompson SD, Lie BA, Flatø B, Førre O, Punaro M, ... ... Hakonarson H, et al. Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis. The Journal of Steroid Biochemistry and Molecular Biology. 145: 113-20. PMID 25460303 DOI: 10.1016/j.jsbmb.2014.10.012  1
2015 Moore TM, Reise SP, Gur RE, Hakonarson H, Gur RC. Psychometric properties of the Penn Computerized Neurocognitive Battery. Neuropsychology. 29: 235-46. PMID 25180981 DOI: 10.1037/neu0000093  1
2015 Mitchell LE, Agopian AJ, Bhalla A, Glessner JT, Kim CE, Swartz MD, Hakonarson H, Goldmuntz E. Genome-wide association study of maternal and inherited effects on left-sided cardiac malformations. Human Molecular Genetics. 24: 265-73. PMID 25138779 DOI: 10.1093/hmg/ddu420  1
2015 Robinson EB, Kirby A, Ruparel K, Yang J, McGrath L, Anttila V, Neale BM, Merikangas K, Lehner T, Sleiman PM, Daly MJ, Gur R, Gur R, Hakonarson H. The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort. Molecular Psychiatry. 20: 454-8. PMID 25023143 DOI: 10.1038/mp.2014.65  1
2015 Erus G, Battapady H, Satterthwaite TD, Hakonarson H, Gur RE, Davatzikos C, Gur RC. Imaging patterns of brain development and their relationship to cognition. Cerebral Cortex (New York, N.Y. : 1991). 25: 1676-84. PMID 24421175 DOI: 10.1093/cercor/bht425  1
2015 Freitag D, Butterworth AS, Willeit P, Howson JMM, Burgess S, Kaptoge S, Young R, Ho WK, Wood AM, Sweeting M, Spackman S, Staley JR, Ramond A, Harshfield E, Nielsen SF, ... ... Hakonarson H, et al. Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis The Lancet Diabetes and Endocrinology. 3: 243-253. DOI: 10.1016/S2213-8587(15)00034-0  1
2014 Banerjee A, Wang HY, Borgmann-Winter KE, MacDonald ML, Kaprielian H, Stucky A, Kvasic J, Egbujo C, Ray R, Talbot K, Hemby SE, Siegel SJ, Arnold SE, Sleiman P, Chang X, ... Hakonarson H, et al. Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia. Molecular Psychiatry. PMID 25330739 DOI: 10.1038/mp.2014.115  1
2014 Calkins ME, Moore TM, Merikangas KR, Burstein M, Satterthwaite TD, Bilker WB, Ruparel K, Chiavacci R, Wolf DH, Mentch F, Qiu H, Connolly JJ, Sleiman PA, Hakonarson H, Gur RC, et al. The psychosis spectrum in a young U.S. community sample: findings from the Philadelphia Neurodevelopmental Cohort. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 13: 296-305. PMID 25273303 DOI: 10.1002/wps.20152  1
2014 Glessner JT, Bick AG, Ito K, Homsy JG, Rodriguez-Murillo L, Fromer M, Mazaika E, Vardarajan B, Italia M, Leipzig J, DePalma SR, Golhar R, Sanders SJ, Yamrom B, Ronemus M, ... ... Hakonarson H, et al. Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data. Circulation Research. 115: 884-96. PMID 25205790 DOI: 10.1161/CIRCRESAHA.115.304458  1
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Hakonarson H, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/jamaneurol.2014.1491  1
2014 Picard M, Zhang J, Hancock S, Derbeneva O, Golhar R, Golik P, O'Hearn S, Levy S, Potluri P, Lvova M, Davila A, Lin CS, Perin JC, Rappaport EF, Hakonarson H, et al. Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming. Proceedings of the National Academy of Sciences of the United States of America. 111: E4033-42. PMID 25192935 DOI: 10.1073/pnas.1414028111  1
2014 Soleimanpour SA, Gupta A, Bakay M, Ferrari AM, Groff DN, Fadista J, Spruce LA, Kushner JA, Groop L, Seeholzer SH, Kaufman BA, Hakonarson H, Stoffers DA. The diabetes susceptibility gene Clec16a regulates mitophagy. Cell. 157: 1577-90. PMID 24949970 DOI: 10.1016/j.cell.2014.05.016  1
2014 Hadley D, Wu ZL, Kao C, Kini A, Mohamed-Hadley A, Thomas K, Vazquez L, Qiu H, Mentch F, Pellegrino R, Kim C, Connolly J, Glessner J, Hakonarson H. The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism. Nature Communications. 5: 4074. PMID 24927284 DOI: 10.1038/ncomms5074  1
2014 Satterthwaite TD, Shinohara RT, Wolf DH, Hopson RD, Elliott MA, Vandekar SN, Ruparel K, Calkins ME, Roalf DR, Gennatas ED, Jackson C, Erus G, Prabhakaran K, Davatzikos C, Detre JA, ... Hakonarson H, et al. Impact of puberty on the evolution of cerebral perfusion during adolescence. Proceedings of the National Academy of Sciences of the United States of America. 111: 8643-8. PMID 24912164 DOI: 10.1073/pnas.1400178111  1
2014 Cook-Sather SD, Li J, Goebel TK, Sussman EM, Rehman MA, Hakonarson H. TAOK3, a novel genome-wide association study locus associated with morphine requirement and postoperative pain in a retrospective pediatric day surgery population. Pain. 155: 1773-83. PMID 24909733 DOI: 10.1016/j.pain.2014.05.032  1
2014 Karayannis T, Au E, Patel JC, Kruglikov I, Markx S, Delorme R, Héron D, Salomon D, Glessner J, Restituito S, Gordon A, Rodriguez-Murillo L, Roy NC, Gogos JA, Rudy B, ... ... Hakonarson H, et al. Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Nature. 511: 236-40. PMID 24870235 DOI: 10.1038/nature13248  1
2014 Yilmaz Z, Kaplan AS, Tiwari AK, Levitan RD, Piran S, Bergen AW, Kaye WH, Hakonarson H, Wang K, Berrettini WH, Brandt HA, Bulik CM, Crawford S, Crow S, Fichter MM, et al. The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa. Journal of Psychiatric Research. 55: 77-86. PMID 24831852 DOI: 10.1016/j.jpsychires.2014.04.005  1
2014 Kim DS, Kim JH, Burt AA, Crosslin DR, Burnham N, McDonald-McGinn DM, Zackai EH, Nicolson SC, Spray TL, Stanaway IB, Nickerson DA, Russell MW, Hakonarson H, Gaynor JW, Jarvik GP. Patient genotypes impact survival after surgery for isolated congenital heart disease. The Annals of Thoracic Surgery. 98: 104-10; discussion 1. PMID 24811984 DOI: 10.1016/j.athoracsur.2014.03.017  1
2014 Agopian AJ, Mitchell LE, Glessner J, Bhalla AD, Sewda A, Hakonarson H, Goldmuntz E. Genome-wide association study of maternal and inherited loci for conotruncal heart defects. Plos One. 9: e96057. PMID 24800985 DOI: 10.1371/journal.pone.0096057  1
2014 Roalf DR, Gur RE, Ruparel K, Calkins ME, Satterthwaite TD, Bilker WB, Hakonarson H, Harris LJ, Gur RC. Within-individual variability in neurocognitive performance: age- and sex-related differences in children and youths from ages 8 to 21. Neuropsychology. 28: 506-18. PMID 24773417 DOI: 10.1037/neu0000067  1
2014 Ingalhalikar M, Smith A, Parker D, Satterthwaite TD, Elliott MA, Ruparel K, Hakonarson H, Gur RE, Gur RC, Verma R. Reply to Joel and Tarrasch: On misreading and shooting the messenger. Proceedings of the National Academy of Sciences of the United States of America. 111: E638. PMID 24672815 DOI: 10.1073/pnas.1323601111  1
2014 Li M, Jia C, Kazmierkiewicz KL, Bowman AS, Tian L, Liu Y, Gupta NA, Gudiseva HV, Yee SS, Kim M, Dentchev T, Kimble JA, Parker JS, Messinger JD, Hakonarson H, et al. Comprehensive analysis of gene expression in human retina and supporting tissues. Human Molecular Genetics. 23: 4001-14. PMID 24634144 DOI: 10.1093/hmg/ddu114  1
2014 Satterthwaite TD, Vandekar S, Wolf DH, Ruparel K, Roalf DR, Jackson C, Elliott MA, Bilker WB, Calkins ME, Prabhakaran K, Davatzikos C, Hakonarson H, Gur RE, Gur RC. Sex differences in the effect of puberty on hippocampal morphology. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 341-50.e1. PMID 24565361 DOI: 10.1016/j.jaac.2013.12.002  1
2014 Gur RC, Calkins ME, Satterthwaite TD, Ruparel K, Bilker WB, Moore TM, Savitt AP, Hakonarson H, Gur RE. Neurocognitive growth charting in psychosis spectrum youths. Jama Psychiatry. 71: 366-74. PMID 24499990 DOI: 10.1001/jamapsychiatry.2013.4190  1
2014 Wang X, Liu W, Sun CL, Armenian SH, Hakonarson H, Hageman L, Ding Y, Landier W, Blanco JG, Chen L, Quiñones A, Ferguson D, Winick N, Ginsberg JP, Keller F, et al. Hyaluronan synthase 3 variant and anthracycline-related cardiomyopathy: a report from the children's oncology group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 647-53. PMID 24470002 DOI: 10.1200/JCO.2013.50.3557  1
2014 Matsunami N, Hensel CH, Baird L, Stevens J, Otterud B, Leppert T, Varvil T, Hadley D, Glessner JT, Pellegrino R, Kim C, Thomas K, Wang F, Otieno FG, Ho K, ... ... Hakonarson H, et al. Identification of rare DNA sequence variants in high-risk autism families and their prevalence in a large case/control population. Molecular Autism. 5: 5. PMID 24467814 DOI: 10.1186/2040-2392-5-5  0.44
2014 Holmes MV, Lange LA, Palmer T, Lanktree MB, North KE, Almoguera B, Buxbaum S, Chandrupatla HR, Elbers CC, Guo Y, Hoogeveen RC, Li J, Li YR, Swerdlow DI, Cushman M, ... ... Hakonarson H, et al. Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis. American Journal of Human Genetics. 94: 198-208. PMID 24462370 DOI: 10.1016/j.ajhg.2013.12.014  1
2014 Kaiser FJ, Ansari M, Braunholz D, Concepción Gil-Rodríguez M, Decroos C, Wilde JJ, Fincher CT, Kaur M, Bando M, Amor DJ, Atwal PS, Bahlo M, Bowman CM, Bradley JJ, Brunner HG, ... ... Hakonarson H, et al. Loss-of-function HDAC8 mutations cause a phenotypic spectrum of Cornelia de Lange syndrome-like features, ocular hypertelorism, large fontanelle and X-linked inheritance. Human Molecular Genetics. 23: 2888-900. PMID 24403048 DOI: 10.1093/hmg/ddu002  1
2014 Yoneyama S, Guo Y, Lanktree MB, Barnes MR, Elbers CC, Karczewski KJ, Padmanabhan S, Bauer F, Baumert J, Beitelshees A, Berenson GS, Boer JM, Burke G, Cade B, Chen W, ... ... Hakonarson H, et al. Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Human Molecular Genetics. 23: 2498-510. PMID 24345515 DOI: 10.1093/hmg/ddt626  1
2014 van der Valk RJ, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA, Genuneit J, Kerhof M, Kreiner-Møller E, Cáceres A, Gref A, Liang LL, Taal HR, Bouzigon E, Demenais F, ... ... Hakonarson H, et al. Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. The Journal of Allergy and Clinical Immunology. 134: 46-55. PMID 24315451 DOI: 10.1016/j.jaci.2013.08.053  1
2014 Ingalhalikar M, Smith A, Parker D, Satterthwaite TD, Elliott MA, Ruparel K, Hakonarson H, Gur RE, Gur RC, Verma R. Sex differences in the structural connectome of the human brain. Proceedings of the National Academy of Sciences of the United States of America. 111: 823-8. PMID 24297904 DOI: 10.1073/pnas.1316909110  1
2014 Bønnelykke K, Sleiman P, Nielsen K, Kreiner-Møller E, Mercader JM, Belgrave D, den Dekker HT, Husby A, Sevelsted A, Faura-Tellez G, Mortensen LJ, Paternoster L, Flaaten R, Mølgaard A, Smart DE, ... ... Hakonarson H, et al. A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nature Genetics. 46: 51-5. PMID 24241537 DOI: 10.1038/ng.2830  1
2014 Babushok DV, Xie HM, Roth JJ, Perdigones N, Olson TS, Cockroft JD, Gai X, Perin JC, Li Y, Paessler ME, Hakonarson H, Podsakoff GM, Mason PJ, Biegel JA, Bessler M. Single nucleotide polymorphism array analysis of bone marrow failure patients reveals characteristic patterns of genetic changes. British Journal of Haematology. 164: 73-82. PMID 24116929 DOI: 10.1111/bjh.12603  1
2014 Tsai EA, Grochowski CM, Loomes KM, Bessho K, Hakonarson H, Bezerra JA, Russo PA, Haber BA, Spinner NB, Devoto M. Replication of a GWAS signal in a Caucasian population implicates ADD3 in susceptibility to biliary atresia. Human Genetics. 133: 235-43. PMID 24104524 DOI: 10.1007/s00439-013-1368-2  1
2014 Li Q, Brodsky JL, Conlin LK, Pawel B, Glatz AC, Gafni RI, Schurgers L, Uitto J, Hakonarson H, Deardorff MA, Levine MA. Mutations in the ABCC6 gene as a cause of generalized arterial calcification of infancy: genotypic overlap with pseudoxanthoma elasticum. The Journal of Investigative Dermatology. 134: 658-65. PMID 24008425 DOI: 10.1038/jid.2013.370  1
2014 Satterthwaite TD, Elliott MA, Ruparel K, Loughead J, Prabhakaran K, Calkins ME, Hopson R, Jackson C, Keefe J, Riley M, Mentch FD, Sleiman P, Verma R, Davatzikos C, Hakonarson H, et al. Neuroimaging of the Philadelphia neurodevelopmental cohort. Neuroimage. 86: 544-53. PMID 23921101 DOI: 10.1016/j.neuroimage.2013.07.064  1
2014 Ahn K, Gotay N, Andersen TM, Anvari AA, Gochman P, Lee Y, Sanders S, Guha S, Darvasi A, Glessner JT, Hakonarson H, Lencz T, State MW, Shugart YY, Rapoport JL. High rate of disease-related copy number variations in childhood onset schizophrenia. Molecular Psychiatry. 19: 568-72. PMID 23689535 DOI: 10.1038/mp.2013.59  1
2014 Ramanan VK, Risacher SL, Nho K, Kim S, Swaminathan S, Shen L, Foroud TM, Hakonarson H, Huentelman MJ, Aisen PS, Petersen RC, Green RC, Jack CR, Koeppe RA, Jagust WJ, et al. APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. Molecular Psychiatry. 19: 351-7. PMID 23419831 DOI: 10.1038/mp.2013.19  1
2013 Siracusa MC, Saenz SA, Wojno ED, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM, Hakonarson H, Cianferoni A, Wang ML, Spergel JM, Comeau MR, et al. Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation. Immunity. 39: 1158-70. PMID 24332033 DOI: 10.1016/j.immuni.2013.09.016  1
2013 Sleiman P, Wang D, Glessner J, Hadley D, Gur RE, Cohen N, Li Q, Hakonarson H. GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus. Scientific Reports. 3: 3075. PMID 24166486 DOI: 10.1038/srep03075  0.44
2013 Satterthwaite TD, Wolf DH, Erus G, Ruparel K, Elliott MA, Gennatas ED, Hopson R, Jackson C, Prabhakaran K, Bilker WB, Calkins ME, Loughead J, Smith A, Roalf DR, Hakonarson H, et al. Functional maturation of the executive system during adolescence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16249-61. PMID 24107956 DOI: 10.1523/JNEUROSCI.2345-13.2013  1
2013 Sajan SA, Fernandez L, Nieh SE, Rider E, Bukshpun P, Wakahiro M, Christian SL, Rivière JB, Sullivan CT, Sudi J, Herriges MJ, Paciorkowski AR, Barkovich AJ, Glessner JT, Millen KJ, ... Hakonarson H, et al. Both rare and de novo copy number variants are prevalent in agenesis of the corpus callosum but not in cerebellar hypoplasia or polymicrogyria. Plos Genetics. 9: e1003823. PMID 24098143 DOI: 10.1371/journal.pgen.1003823  1
2013 Chatsuriyawong S, Gozal D, Kheirandish-Gozal L, Bhattacharjee R, Khalyfa AA, Wang Y, Hakonarson H, Keating B, Sukhumsirichart W, Khalyfa A. Genetic variance in nitric oxide synthase and endothelin genes among children with and without endothelial dysfunction. Journal of Translational Medicine. 11: 227. PMID 24063765 DOI: 10.1186/1479-5876-11-227  1
2013 Ong BA, Li J, McDonough JM, Wei Z, Kim C, Chiavacci R, Mentch F, Caboot JB, Spergel J, Allen JL, Sleiman PM, Hakonarson H. Gene network analysis in a pediatric cohort identifies novel lung function genes. Plos One. 8: e72899. PMID 24023788 DOI: 10.1371/journal.pone.0072899  0.44
2013 Kasperaviciute D, Catarino CB, Matarin M, Leu C, Novy J, Tostevin A, Leal B, Hessel EV, Hallmann K, Hildebrand MS, Dahl HH, Ryten M, Trabzuni D, Ramasamy A, Alhusaini S, ... ... Hakonarson H, et al. Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A. Brain : a Journal of Neurology. 136: 3140-50. PMID 24014518 DOI: 10.1093/brain/awt233  1
2013 Best LG, Saxena R, Anderson CM, Barnes MR, Hakonarson H, Falcon G, Martin C, Castillo BA, Karumanchi A, Keplin K, Pearson N, Lamb F, Bercier S, Keating BJ. Two variants of the C-reactive protein gene are associated with risk of pre-eclampsia in an American Indian population. Plos One. 8: e71231. PMID 23940726 DOI: 10.1371/journal.pone.0071231  1
2013 Tsai EA, Berman MA, Conlin LK, Rehm HL, Francey LJ, Deardorff MA, Holst J, Kaur M, Gallant E, Clark DM, Glessner JT, Jensen ST, Grant SF, Gruber PJ, Hakonarson H, et al. PECONPI: a novel software for uncovering pathogenic copy number variations in non-syndromic sensorineural hearing loss and other genetically heterogeneous disorders. American Journal of Medical Genetics. Part A. 161: 2134-47. PMID 23897863 DOI: 10.1002/ajmg.a.36038  1
2013 Wang K, Kim C, Bradfield J, Guo Y, Toskala E, Otieno FG, Hou C, Thomas K, Cardinale C, Lyon GJ, Golhar R, Hakonarson H. Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement. Genome Medicine. 5: 67. PMID 23889995 DOI: 10.1186/gm471  1
2013 Al Daama SA, Housawi YH, Dridi W, Sager M, Otieno FG, Hou C, Vasquez L, Kim C, Tian L, Sleiman P, Hakonarson H. A missense mutation in ANKRD26 segregates with thrombocytopenia Blood. 122: 461-462. PMID 23869080 DOI: 10.1182/blood-2013-03-489344  0.44
2013 Pinney SE, Ganapathy K, Bradfield J, Stokes D, Sasson A, Mackiewicz K, Boodhansingh K, Hughes N, Becker S, Givler S, Macmullen C, Monos D, Ganguly A, Hakonarson H, Stanley CA. Dominant form of congenital hyperinsulinism maps to HK1 region on 10q. Hormone Research in PæDiatrics. 80: 18-27. PMID 23859901 DOI: 10.1159/000351943  1
2013 Gur RE, Kaltman D, Melhem ER, Ruparel K, Prabhakaran K, Riley M, Yodh E, Hakonarson H, Satterthwaite T, Gur RC. Incidental findings in youths volunteering for brain MRI research. Ajnr. American Journal of Neuroradiology. 34: 2021-5. PMID 23811972 DOI: 10.3174/ajnr.A3525  1
2013 Satterthwaite TD, Wolf DH, Ruparel K, Erus G, Elliott MA, Eickhoff SB, Gennatas ED, Jackson C, Prabhakaran K, Smith A, Hakonarson H, Verma R, Davatzikos C, Gur RE, Gur RC. Heterogeneous impact of motion on fundamental patterns of developmental changes in functional connectivity during youth. Neuroimage. 83: 45-57. PMID 23792981 DOI: 10.1016/j.neuroimage.2013.06.045  1
2013 Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisholm RL, Chute CG, Connolly JJ, ... ... Hakonarson H, et al. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 761-71. PMID 23743551 DOI: 10.1038/gim.2013.72  1
2013 Martignetti JA, Tian L, Li D, Ramirez MC, Camacho-Vanegas O, Camacho SC, Guo Y, Zand DJ, Bernstein AM, Masur SK, Kim CE, Otieno FG, Hou C, Abdel-Magid N, Tweddale B, ... ... Hakonarson H, et al. Mutations in PDGFRB cause autosomal-dominant infantile myofibromatosis. American Journal of Human Genetics. 92: 1001-7. PMID 23731542 DOI: 10.1016/j.ajhg.2013.04.024  1
2013 Wei Z, Wang W, Bradfield J, Li J, Cardinale C, Frackelton E, Kim C, Mentch F, Van Steen K, Visscher PM, Baldassano RN, Hakonarson H. Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease American Journal of Human Genetics. 92: 1008-1012. PMID 23731541 DOI: 10.1016/j.ajhg.2013.05.002  0.44
2013 Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, Romano-Adesman A, Bjornson RD, Breitbart RE, Brown KK, Carriero NJ, Cheung YH, Deanfield J, DePalma S, Fakhro KA, ... ... Hakonarson H, et al. De novo mutations in histone-modifying genes in congenital heart disease. Nature. 498: 220-3. PMID 23665959 DOI: 10.1038/nature12141  1
2013 Zhang W, Hui KY, Gusev A, Warner N, Ng SM, Ferguson J, Choi M, Burberry A, Abraham C, Mayer L, Desnick RJ, Cardinale CJ, Hakonarson H, Waterman M, Chowers Y, et al. Extended haplotype association study in Crohn's disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-κB pathway gene, HEATR3. Genes and Immunity. 14: 310-6. PMID 23615072 DOI: 10.1038/gene.2013.19  1
2013 Hamshere ML, Langley K, Martin J, Agha SS, Stergiakouli E, Anney RJ, Buitelaar J, Faraone SV, Lesch KP, Neale BM, Franke B, Sonuga-Barke E, Asherson P, Merwood A, Kuntsi J, ... ... Hakonarson H, et al. High loading of polygenic risk for ADHD in children with comorbid aggression. The American Journal of Psychiatry. 170: 909-16. PMID 23599091 DOI: 10.1176/appi.ajp.2013.12081129  1
2013 Shi L, Zhang X, Golhar R, Otieno FG, He M, Hou C, Kim C, Keating B, Lyon GJ, Wang K, Hakonarson H. Whole-genome sequencing in an autism multiplex family. Molecular Autism. 4: 8. PMID 23597238 DOI: 10.1186/2040-2392-4-8  1
2013 O'Rawe J, Jiang T, Sun G, Wu Y, Wang W, Hu J, Bodily P, Tian L, Hakonarson H, Johnson WE, Wei Z, Wang K, Lyon GJ. Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing. Genome Medicine. 5: 28. PMID 23537139 DOI: 10.1186/gm432  1
2013 Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Byrne EM, Taal HR, Huikari V, Bradfield JP, Kerkhof M, Groen-Blokhuis MM, Kreiner-Møller E, Marinelli M, Holst C, Leinonen JT, ... ... Hakonarson H, et al. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics. 22: 2735-47. PMID 23449627 DOI: 10.1093/hmg/ddt104  1
2013 Chen Z, Tang H, Qayyum R, Schick UM, Nalls MA, Handsaker R, Li J, Lu Y, Yanek LR, Keating B, Meng Y, van Rooij FJ, Okada Y, Kubo M, Rasmussen-Torvik L, ... ... Hakonarson H, et al. Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. Human Molecular Genetics. 22: 2529-38. PMID 23446634 DOI: 10.1093/hmg/ddt087  1
2013 Glessner JT, Smith AV, Panossian S, Kim CE, Takahashi N, Thomas KA, Wang F, Seidler K, Harris TB, Launer LJ, Keating B, Connolly J, Sleiman PM, Buxbaum JD, Grant SF, ... ... Hakonarson H, et al. Copy number variations in alternative splicing gene networks impact lifespan. Plos One. 8: e53846. PMID 23382853 DOI: 10.1371/journal.pone.0053846  1
2013 Matsunami N, Hadley D, Hensel CH, Christensen GB, Kim C, Frackelton E, Thomas K, da Silva RP, Stevens J, Baird L, Otterud B, Ho K, Varvil T, Leppert T, Lambert CG, ... ... Hakonarson H, et al. Identification of rare recurrent copy number variants in high-risk autism families and their prevalence in a large ASD population. Plos One. 8: e52239. PMID 23341896 DOI: 10.1371/journal.pone.0052239  0.44
2013 Cui S, Leyva-Vega M, Tsai EA, EauClaire SF, Glessner JT, Hakonarson H, Devoto M, Haber BA, Spinner NB, Matthews RP. Evidence from human and zebrafish that GPC1 is a biliary atresia susceptibility gene. Gastroenterology. 144: 1107-1115.e3. PMID 23336978 DOI: 10.1053/j.gastro.2013.01.022  1
2013 Li J, Glessner JT, Zhang H, Hou C, Wei Z, Bradfield JP, Mentch FD, Guo Y, Kim C, Xia Q, Chiavacci RM, Thomas KA, Qiu H, Grant SF, Furth SL, ... Hakonarson H, et al. GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Human Molecular Genetics. 22: 1457-64. PMID 23263863 DOI: 10.1093/hmg/dds534  0.44
2013 Guo Y, Lanktree MB, Taylor KC, Hakonarson H, Lange LA, Keating BJ, Fairfax BP, Elbers CC, Barnard J, Farrall M, Padmanabhan S, Baumert J, Castillo BA, Gaunt TR, Gong Y, et al. Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals Human Molecular Genetics. 22: 184-201. PMID 23001569 DOI: 10.1093/hmg/dds396  1
2012 Lasky-Su J, Himes BE, Raby BA, Klanderman BJ, Sylvia JS, Lange C, Melen E, Martinez FD, Israel E, Gauderman J, Gilliland F, Sleiman P, Hakonarson H, Celedón JC, Soto-Quiros M, et al. HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 42: 1724-33. PMID 23181788 DOI: 10.1111/cea.12000  1
2012 Williams AL, Patterson N, Glessner J, Hakonarson H, Reich D. Phasing of many thousands of genotyped samples. American Journal of Human Genetics. 91: 238-51. PMID 22883141 DOI: 10.1016/j.ajhg.2012.06.013  1
2012 Deardorff MA, Wilde JJ, Albrecht M, Dickinson E, Tennstedt S, Braunholz D, Mönnich M, Yan Y, Xu W, Gil-Rodríguez MC, Clark D, Hakonarson H, Halbach S, Michelis LD, Rampuria A, et al. RAD21 mutations cause a human cohesinopathy. American Journal of Human Genetics. 90: 1014-27. PMID 22633399 DOI: 10.1016/j.ajhg.2012.04.019  1
2012 Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Mojsilovic-Petrovic J, Panossian S, Kim CE, Frackelton EC, Solski JA, Williams KL, Clay-Falcone D, ... ... Hakonarson H, et al. Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Human Molecular Genetics. 21: 2899-911. PMID 22454397 DOI: 10.1093/hmg/dds116  1
2012 Kenny EE, Pe'er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant SR, Bressman S, Burns ER, ... ... Hakonarson H, et al. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. Plos Genetics. 8: e1002559. PMID 22412388 DOI: 10.1371/journal.pgen.1002559  1
2012 Bosse KR, Diskin SJ, Cole KA, Wood AC, Schnepp RW, Norris G, Nguyen le B, Jagannathan J, Laquaglia M, Winter C, Diamond M, Hou C, Attiyeh EF, Mosse YP, Pineros V, ... ... Hakonarson H, et al. Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity. Cancer Research. 72: 2068-78. PMID 22350409 DOI: 10.1158/0008-5472.CAN-11-3703  1
2012 Gur RC, Richard J, Calkins ME, Chiavacci R, Hansen JA, Bilker WB, Loughead J, Connolly JJ, Qiu H, Mentch FD, Abou-Sleiman PM, Hakonarson H, Gur RE. Age group and sex differences in performance on a computerized neurocognitive battery in children age 8-21. Neuropsychology. 26: 251-65. PMID 22251308 DOI: 10.1037/a0026712  1
2012 Casey JP, Magalhaes T, Conroy JM, Regan R, Shah N, Anney R, Shields DC, Abrahams BS, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, ... ... Hakonarson H, et al. A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Human Genetics. 131: 565-79. PMID 21996756 DOI: 10.1007/s00439-011-1094-6  1
2012 Huff CD, Witherspoon DJ, Zhang Y, Gatenbee C, Denson LA, Kugathasan S, Hakonarson H, Whiting A, Davis CT, Wu W, Xing J, Watkins WS, Bamshad MJ, Bradfield JP, Bulayeva K, et al. Crohn's disease and genetic hitchhiking at IBD5. Molecular Biology and Evolution. 29: 101-11. PMID 21816865 DOI: 10.1093/molbev/msr151  1
2011 Chung RH, Ma D, Wang K, Hedges DJ, Jaworski JM, Gilbert JR, Cuccaro ML, Wright HH, Abramson RK, Konidari I, Whitehead PL, Schellenberg GD, Hakonarson H, Haines JL, Pericak-Vance MA, et al. An X chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males. Molecular Autism. 2: 18. PMID 22050706 DOI: 10.1186/2040-2392-2-18  1
2011 Goldmuntz E, Paluru P, Glessner J, Hakonarson H, Biegel JA, White PS, Gai X, Shaikh TH. Microdeletions and microduplications in patients with congenital heart disease and multiple congenital anomalies. Congenital Heart Disease. 6: 592-602. PMID 22010865 DOI: 10.1111/j.1747-0803.2011.00582.x  1
2011 Ashokkumar C, Ningappa M, Ranganathan S, Higgs BW, Sun Q, Schmitt L, Snyder S, Dobberstein J, Branca M, Jaffe R, Zeevi A, Squires R, Alissa F, Shneider B, Soltys K, ... ... Hakonarson H, et al. Increased expression of peripheral blood leukocyte genes implicate CD14+ tissue macrophages in cellular intestine allograft rejection. The American Journal of Pathology. 179: 1929-38. PMID 21854741 DOI: 10.1016/j.ajpath.2011.06.040  1
2011 Wei Z, Wang W, Hu P, Lyon GJ, Hakonarson H. SNVer: a statistical tool for variant calling in analysis of pooled or individual next-generation sequencing data. Nucleic Acids Research. 39: e132. PMID 21813454 DOI: 10.1093/nar/gkr599  1
2011 Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, Palmer CD, Chen GK, Wang K, Buxbaum SG, Akylbekova EL, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, ... ... Hakonarson H, et al. The landscape of recombination in African Americans. Nature. 476: 170-5. PMID 21775986 DOI: 10.1038/nature10336  1
2011 Rope AF, Wang K, Evjenth R, Xing J, Johnston JJ, Swensen JJ, Johnson WE, Moore B, Huff CD, Bird LM, Carey JC, Opitz JM, Stevens CA, Jiang T, Schank C, ... ... Hakonarson H, et al. Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency. American Journal of Human Genetics. 89: 28-43. PMID 21700266 DOI: 10.1016/j.ajhg.2011.05.017  1
2011 Höglinger GU, Melhem NM, Dickson DW, Sleiman PM, Wang LS, Klei L, Rademakers R, de Silva R, Litvan I, Riley DE, van Swieten JC, Heutink P, Wszolek ZK, Uitti RJ, Vandrovcova J, ... ... Hakonarson H, et al. Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nature Genetics. 43: 699-705. PMID 21685912 DOI: 10.1038/ng.859  1
2011 Kanetsky PA, Mitra N, Vardhanabhuti S, Vaughn DJ, Li M, Ciosek SL, Letrero R, D'Andrea K, Vaddi M, Doody DR, Weaver J, Chen C, Starr JR, HÃ¥konarson H, Rader DJ, et al. A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. Human Molecular Genetics. 20: 3109-17. PMID 21551455 DOI: 10.1093/hmg/ddr207  1
2011 Nguyen le B, Diskin SJ, Capasso M, Wang K, Diamond MA, Glessner J, Kim C, Attiyeh EF, Mosse YP, Cole K, Iolascon A, Devoto M, Hakonarson H, Li HK, Maris JM. Phenotype restricted genome-wide association study using a gene-centric approach identifies three low-risk neuroblastoma susceptibility Loci. Plos Genetics. 7: e1002026. PMID 21436895 DOI: 10.1371/journal.pgen.1002026  0.44
2011 Levinson DF, Duan J, Oh S, Wang K, Sanders AR, Shi J, Zhang N, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, ... ... Hakonarson H, et al. Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. The American Journal of Psychiatry. 168: 302-16. PMID 21285140 DOI: 10.1176/appi.ajp.2010.10060876  1
2011 Elia J, Gai X, Hakonarson H, White PS. Structural variations in attention-deficit hyperactivity disorder. Lancet. 377: 377-8; author reply . PMID 21277432 DOI: 10.1016/S0140-6736(11)60120-7  1
2011 Sharma S, Gao X, Londono D, Devroy SE, Mauldin KN, Frankel JT, Brandon JM, Zhang D, Li QZ, Dobbs MB, Gurnett CA, Grant SF, Hakonarson H, Dormans JP, Herring JA, et al. Genome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes. Human Molecular Genetics. 20: 1456-66. PMID 21216876 DOI: 10.1093/hmg/ddq571  1
2011 Wang K, Diskin SJ, Zhang H, Attiyeh EF, Winter C, Hou C, Schnepp RW, Diamond M, Bosse K, Mayes PA, Glessner J, Kim C, Frackelton E, Garris M, Wang Q, ... ... Hakonarson H, et al. Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Nature. 469: 216-20. PMID 21124317 DOI: 10.1038/nature09609  0.44
2011 Ningappa M, Higgs BW, Weeks DE, Ashokkumar C, Duerr RH, Sun Q, Soltys KA, Bond GJ, Abu-Elmagd K, Mazariegos GV, Alissa F, Rivera M, Rudolph J, Squires R, Hakonarson H, et al. NOD2 gene polymorphism rs2066844 associates with need for combined liver-intestine transplantation in children with short-gut syndrome. The American Journal of Gastroenterology. 106: 157-65. PMID 20959815 DOI: 10.1038/ajg.2010.322  1
2010 Glessner JT, Bradfield JP, Wang K, Takahashi N, Zhang H, Sleiman PM, Mentch FD, Kim CE, Hou C, Thomas KA, Garris ML, Deliard S, Frackelton EC, Otieno FG, Zhao J, ... ... Hakonarson H, et al. A genome-wide study reveals copy number variants exclusive to childhood obesity cases. American Journal of Human Genetics. 87: 661-6. PMID 20950786 DOI: 10.1016/j.ajhg.2010.09.014  1
2010 Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF, Erdmann J, Willenborg C, Vaidya D, Xie C, Patterson CC, Morgan TM, Burnett MS, Li M, Hlatky MA, ... ... Hakonarson H, et al. Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. Journal of the American College of Cardiology. 56: 1552-63. PMID 20933357 DOI: 10.1016/j.jacc.2010.06.022  1
2010 Waterworth DM, Ricketts SL, Song K, Chen L, Zhao JH, Ripatti S, Aulchenko YS, Zhang W, Yuan X, Lim N, Luan J, Ashford S, Wheeler E, Young EH, Hadley D, ... ... Hakonarson HH, et al. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2264-76. PMID 20864672 DOI: 10.1161/ATVBAHA.109.201020  1
2010 Neale BM, Medland SE, Ripke S, Asherson P, Franke B, Lesch KP, Faraone SV, Nguyen TT, Schäfer H, Holmans P, Daly M, Steinhausen HC, Freitag C, Reif A, Renner TJ, ... ... Hakonarson H, et al. Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 49: 884-97. PMID 20732625 DOI: 10.1016/j.jaac.2010.06.008  1
2010 Takeda T, Stotesbery K, Power T, Ambrosini PJ, Berrettini W, Hakonarson H, Elia J. Parental ADHD status and its association with proband ADHD subtype and severity. The Journal of Pediatrics. 157: 995-1000.e1. PMID 20630538 DOI: 10.1016/j.jpeds.2010.05.053  1
2010 Wong SH, Gochhait S, Malhotra D, Pettersson FH, Teo YY, Khor CC, Rautanen A, Chapman SJ, Mills TC, Srivastava A, Rudko A, Freidin MB, Puzyrev VP, Ali S, Aggarwal S, ... ... Hakonarson H, et al. Leprosy and the adaptation of human toll-like receptor 1. Plos Pathogens. 6: e1000979. PMID 20617178 DOI: 10.1371/journal.ppat.1000979  1
2010 Lantieri F, Glessner JT, Hakonarson H, Elia J, Devoto M. Analysis of GWAS top hits in ADHD suggests association to two polymorphisms located in genes expressed in the cerebellum. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1127-33. PMID 20607790 DOI: 10.1002/ajmg.b.31110  1
2010 Stevens KN, Hakonarson H, Kim CE, Doevendans PA, Koeleman BP, Mital S, Raue J, Glessner JT, Coles JG, Moreno V, Granger A, Gruber SB, Gruber PJ. Common variation in ISL1 confers genetic susceptibility for human congenital heart disease. Plos One. 5: e10855. PMID 20520780 DOI: 10.1371/journal.pone.0010855  1
2010 Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, Berrettini W, Knouff CW, Yuan X, Waeber G, Vollenweider P, Preisig M, Wareham NJ, Zhao JH, Loos RJ, ... ... Hakonarson HH, et al. Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nature Genetics. 42: 436-40. PMID 20418889 DOI: 10.1038/ng.572  1
2010 Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ, Warrington NM, Widen E, Hottenga JJ, Kaakinen M, Lange LA, Bradfield JP, Kerkhof M, Marsh JA, Mägi R, ... ... Hakonarson H, et al. Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics. 42: 430-5. PMID 20372150 DOI: 10.1038/ng.567  1
2010 Leyva-Vega M, Gerfen J, Thiel BD, Jurkiewicz D, Rand EB, Pawlowska J, Kaminska D, Russo P, Gai X, Krantz ID, Kamath BM, Hakonarson H, Haber BA, Spinner NB. Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3. American Journal of Medical Genetics. Part A. 152: 886-95. PMID 20358598 DOI: 10.1002/ajmg.a.33332  1
2010 Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, Annese V, Dubinsky M, Rotter JI, Russell RK, Bradfield JP, Sleiman PM, Glessner JT, Walters T, Hou C, ... ... Hakonarson H, et al. Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Human Molecular Genetics. 19: 2059-67. PMID 20176734 DOI: 10.1093/hmg/ddq078  1
2010 Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, ... ... Hakonarson H, et al. Variants of DENND1B associated with asthma in children. The New England Journal of Medicine. 362: 36-44. PMID 20032318 DOI: 10.1056/NEJMoa0901867  1
2010 Dubinsky MC, Mei L, Friedman M, Dhere T, Haritunians T, Hakonarson H, Kim C, Glessner J, Targan SR, McGovern DP, Taylor KD, Rotter JI. Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 16: 1357-66. PMID 20014019 DOI: 10.1002/ibd.21174  1
2010 Fairfax BP, Vannberg FO, Radhakrishnan J, Hakonarson H, Keating BJ, Hill AV, Knight JC. An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6. Human Molecular Genetics. 19: 720-30. PMID 19942621 DOI: 10.1093/hmg/ddp530  1
2010 Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, ... ... Hakonarson H, et al. A genome-wide association study on African-ancestry populations for asthma. The Journal of Allergy and Clinical Immunology. 125: 336-346.e4. PMID 19910028 DOI: 10.1016/j.jaci.2009.08.031  1
2010 Elia J, Gai X, Xie HM, Perin JC, Geiger E, Glessner JT, D'arcy M, deBerardinis R, Frackelton E, Kim C, Lantieri F, Muganga BM, Wang L, Takeda T, Rappaport EF, ... ... Hakonarson H, et al. Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes. Molecular Psychiatry. 15: 637-46. PMID 19546859 DOI: 10.1038/mp.2009.57  1
2009 Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y, ... ... Hakonarson HH, et al. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nature Genetics. 41: 1182-90. PMID 19820697 DOI: 10.1038/ng.467  1
2009 Wei Z, Wang K, Qu HQ, Zhang H, Bradfield J, Kim C, Frackleton E, Hou C, Glessner JT, Chiavacci R, Stanley C, Monos D, Grant SF, Polychronakos C, Hakonarson H. From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes. Plos Genetics. 5: e1000678. PMID 19816555 DOI: 10.1371/journal.pgen.1000678  0.44
2009 Scherr R, Essers J, Hakonarson H, Kugathasan S. Genetic determinants of pediatric inflammatory bowel disease: is age of onset genetically determined? Digestive Diseases (Basel, Switzerland). 27: 236-9. PMID 19786746 DOI: 10.1159/000228555  1
2009 Flory JH, Sleiman PM, Christie JD, Annaiah K, Bradfield J, Kim CE, Glessner J, Imielinski M, Li H, Frackelton EC, Cuiping H, Otieno G, Thomas K, Smith R, Glaberson W, ... ... Hakonarson H, et al. 17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry. The Journal of Allergy and Clinical Immunology. 124: 605-7. PMID 19660801 DOI: 10.1016/j.jaci.2009.05.047  1
2009 Shaikh TH, Gai X, Perin JC, Glessner JT, Xie H, Murphy K, O'Hara R, Casalunovo T, Conlin LK, D'Arcy M, Frackelton EC, Geiger EA, Haldeman-Englert C, Imielinski M, Kim CE, ... ... Hakonarson H, et al. High-resolution mapping and analysis of copy number variations in the human genome: a data resource for clinical and research applications. Genome Research. 19: 1682-90. PMID 19592680 DOI: 10.1101/gr.083501.108  1
2009 Bucan M, Abrahams BS, Wang K, Glessner JT, Herman EI, Sonnenblick LI, Alvarez Retuerto AI, Imielinski M, Hadley D, Bradfield JP, Kim C, Gidaya NB, Lindquist I, Hutman T, Sigman M, ... ... Hakonarson H, et al. Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes. Plos Genetics. 5: e1000536. PMID 19557195 DOI: 10.1371/journal.pgen.1000536  1
2009 Diskin SJ, Hou C, Glessner JT, Attiyeh EF, Laudenslager M, Bosse K, Cole K, Mossé YP, Wood A, Lynch JE, Pecor K, Diamond M, Winter C, Wang K, Kim C, ... ... Hakonarson H, et al. Copy number variation at 1q21.1 associated with neuroblastoma. Nature. 459: 987-91. PMID 19536264 DOI: 10.1038/nature08035  1
2009 Elia J, Takeda T, Deberardinis R, Burke J, Accardo J, Ambrosini PJ, Blum NJ, Brown LW, Lantieri F, Berrettini W, Devoto M, Hakonarson H. Nocturnal enuresis: a suggestive endophenotype marker for a subgroup of inattentive attention-deficit/hyperactivity disorder. The Journal of Pediatrics. 155: 239-44.e5. PMID 19446845 DOI: 10.1016/j.jpeds.2009.02.031  1
2009 Himes BE, Hunninghake GM, Baurley JW, Rafaels NM, Sleiman P, Strachan DP, Wilk JB, Willis-Owen SA, Klanderman B, Lasky-Su J, Lazarus R, Murphy AJ, Soto-Quiros ME, Avila L, Beaty T, ... ... Hakonarson H, et al. Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. American Journal of Human Genetics. 84: 581-93. PMID 19426955 DOI: 10.1016/j.ajhg.2009.04.006  1
2009 Capasso M, Devoto M, Hou C, Asgharzadeh S, Glessner JT, Attiyeh EF, Mosse YP, Kim C, Diskin SJ, Cole KA, Bosse K, Diamond M, Laudenslager M, Winter C, Bradfield JP, ... ... Hakonarson H, et al. Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nature Genetics. 41: 718-23. PMID 19412175 DOI: 10.1038/ng.374  0.44
2009 Glessner JT, Wang K, Cai G, Korvatska O, Kim CE, Wood S, Zhang H, Estes A, Brune CW, Bradfield JP, Imielinski M, Frackelton EC, Reichert J, Crawford EL, Munson J, ... ... Hakonarson H, et al. Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature. 459: 569-73. PMID 19404257 DOI: 10.1038/nature07953  1
2009 Jackson EM, Sievert AJ, Gai X, Hakonarson H, Judkins AR, Tooke L, Perin JC, Xie H, Shaikh TH, Biegel JA. Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1923-30. PMID 19276269 DOI: 10.1158/1078-0432.CCR-08-2091  1
2009 Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, Russell RK, Sleiman PM, Imielinski M, Glessner J, Hou C, Wilson DC, Walters T, Kim C, Frackelton EC, Lionetti P, ... ... Hakonarson H, et al. Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. American Journal of Human Genetics. 84: 399-405. PMID 19249008 DOI: 10.1016/j.ajhg.2009.01.026  1
2009 Attiyeh EF, Diskin SJ, Attiyeh MA, Mossé YP, Hou C, Jackson EM, Kim C, Glessner J, Hakonarson H, Biegel JA, Maris JM. Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy. Genome Research. 19: 276-83. PMID 19141597 DOI: 10.1101/gr.075671.107  0.44
2009 Haldeman-Englert CR, Gai X, Perin JC, Ciano M, Halbach SS, Geiger EA, McDonald-McGinn DM, Hakonarson H, Zackai EH, Shaikh TH. A 3.1-Mb microdeletion of 3p21.31 associated with cortical blindness, cleft lip, CNS abnormalities, and developmental delay. European Journal of Medical Genetics. 52: 265-8. PMID 19100872 DOI: 10.1016/j.ejmg.2008.11.005  1
2009 Kamath BM, Thiel BD, Gai X, Conlin LK, Munoz PS, Glessner J, Clark D, Warthen DM, Shaikh TH, Mihci E, Piccoli DA, Grant SF, Hakonarson H, Krantz ID, Spinner NB. SNP array mapping of chromosome 20p deletions: genotypes, phenotypes, and copy number variation. Human Mutation. 30: 371-8. PMID 19058200 DOI: 10.1002/humu.20863  1
2009 Sievert AJ, Jackson EM, Gai X, Hakonarson H, Judkins AR, Resnick AC, Sutton LN, Storm PB, Shaikh TH, Biegel JA. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathology (Zurich, Switzerland). 19: 449-58. PMID 19016743 DOI: 10.1111/j.1750-3639.2008.00225.x  1
2008 Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, ... ... Hakonarson H, et al. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. Plos One. 3: e3583. PMID 18974833 DOI: 10.1371/journal.pone.0003583  1
2008 Sleiman PM, Annaiah K, Imielinski M, Bradfield JP, Kim CE, Frackelton EC, Glessner JT, Eckert AW, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson W, Garris M, Gunnlaugsson S, ... ... Hakonarson H, et al. ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry. The Journal of Allergy and Clinical Immunology. 122: 1225-7. PMID 18760456 DOI: 10.1016/j.jaci.2008.06.041  1
2008 Mossé YP, Laudenslager M, Longo L, Cole KA, Wood A, Attiyeh EF, Laquaglia MJ, Sennett R, Lynch JE, Perri P, Laureys G, Speleman F, Kim C, Hou C, Hakonarson H, et al. Identification of ALK as a major familial neuroblastoma predisposition gene. Nature. 455: 930-5. PMID 18724359 DOI: 10.1038/nature07261  0.44
2008 Maris JM, Mosse YP, Bradfield JP, Hou C, Monni S, Scott RH, Asgharzadeh S, Attiyeh EF, Diskin SJ, Laudenslager M, Winter C, Cole KA, Glessner JT, Kim C, Frackelton EC, ... ... Hakonarson H, et al. Chromosome 6p22 locus associated with clinically aggressive neuroblastoma. The New England Journal of Medicine. 358: 2585-93. PMID 18463370 DOI: 10.1056/NEJMoa0708698  0.44
2007 Jackson EM, Shaikh TH, Zhang F, Wainwright LM, Storm PB, Hakonarson H, Zackai EH, Biegel JA. Atypical teratoid/rhabdoid tumor in a patient with Beckwith-Wiedemann syndrome. American Journal of Medical Genetics. Part A. 143: 1767-70. PMID 17603804 DOI: 10.1002/ajmg.a.31843  1
2006 Helgadottir A, Manolescu A, Helgason A, Thorleifsson G, Thorsteinsdottir U, Gudbjartsson DF, Gretarsdottir S, Magnusson KP, Gudmundsson G, Hicks A, Jonsson T, Grant SF, Sainz J, O'Brien SJ, Sveinbjornsdottir S, ... ... Hakonarson H, et al. A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nature Genetics. 38: 68-74. PMID 16282974 DOI: 10.1038/ng1692  1
2005 Hakonarson H, Bjornsdottir US, Halapi E, Bradfield J, Zink F, Mouy M, Helgadottir H, Gudmundsdottir AS, Andrason H, Adalsteinsdottir AE, Kristjansson K, Birkisson I, Arnason T, Andresdottir M, Gislason D, et al. Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients. Proceedings of the National Academy of Sciences of the United States of America. 102: 14789-94. PMID 16203992 DOI: 10.1073/pnas.0409904102  1
2005 Thakkinstian A, McEvoy M, Minelli C, Gibson P, Hancox B, Duffy D, Thompson J, Hall I, Kaufman J, Leung TF, Helms PJ, Hakonarson H, Halpi E, Navon R, Attia J. Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE review. American Journal of Epidemiology. 162: 201-11. PMID 15987731 DOI: 10.1093/aje/kwi184  1
2004 Pack AI, Gislason T, Hakonarson H. Linkage to apnea-hypopnea index across the life-span: is this a viable strategy? American Journal of Respiratory and Critical Care Medicine. 170: 1260; author reply 1. PMID 15563643 DOI: 10.1164/ajrccm.170.11.951  1
2004 Whelan R, Kim C, Chen M, Leiter J, Grunstein MM, Hakonarson H. Role and regulation of interleukin-1 molecules in pro-asthmatic sensitised airway smooth muscle. The European Respiratory Journal. 24: 559-67. PMID 15459133 DOI: 10.1183/09031936.04.00133803  1
2004 Helgadottir A, Manolescu A, Thorleifsson G, Gretarsdottir S, Jonsdottir H, Thorsteinsdottir U, Samani NJ, Gudmundsson G, Grant SF, Thorgeirsson G, Sveinbjornsdottir S, Valdimarsson EM, Matthiasson SE, Johannsson H, Gudmundsdottir O, ... ... Hakonarson H, et al. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nature Genetics. 36: 233-9. PMID 14770184 DOI: 10.1038/ng1311  1
2003 Hakonarson H, Grunstein MM. Autocrine regulation of airway smooth muscle responsiveness. Respiratory Physiology & Neurobiology. 137: 263-76. PMID 14516731 DOI: 10.1016/S1569-9048(03)00152-6  1
2002 Hakonarson H, Whelan R, Leiter J, Kim C, Chen M, Campbell D, Grunstein MM. T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. The Journal of Allergy and Clinical Immunology. 110: 624-33. PMID 12373272 DOI: 10.1067/mai.2002.128529  1
2002 Grunstein MM, Hakonarson H, Leiter J, Chen M, Whelan R, Grunstein JS, Chuang S. IL-13-dependent autocrine signaling mediates altered responsiveness of IgE-sensitized airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L520-8. PMID 11839548 DOI: 10.1152/ajplung.00343.2001  1
2001 Grunstein MM, Hakonarson H, Whelan R, Yu Z, Grunstein JS, Chuang S. Rhinovirus elicits proasthmatic changes in airway responsiveness independently of viral infection. The Journal of Allergy and Clinical Immunology. 108: 997-1004. PMID 11742279 DOI: 10.1067/mai.2001.120276  1
2001 Hakonarson H, Halapi E, Whelan R, Gulcher J, Stefansson K, Grunstein MM. Association between IL-1beta/TNF-alpha-induced glucocorticoid-sensitive changes in multiple gene expression and altered responsiveness in airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 25: 761-71. PMID 11726403 DOI: 10.1165/ajrcmb.25.6.4628  1
2001 Grunstein MM, Hakonarson H, Leiter J, Chen M, Whelan R, Grunstein JS, Chuang S. Autocrine signaling by IL-10 mediates altered responsiveness of atopic sensitized airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L1130-7. PMID 11597904  1
2001 Grunstein MM, Hakonarson H, Hodinka RL, Maskeri N, Kim C, Chuang S. Mechanism of cooperative effects of rhinovirus and atopic sensitization on airway responsiveness. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L229-38. PMID 11159001  1
2001 Hakonarson H, Kim C, Whelan R, Campbell D, Grunstein MM. Bi-directional activation between human airway smooth muscle cells and T lymphocytes: role in induction of altered airway responsiveness. Journal of Immunology (Baltimore, Md. : 1950). 166: 293-303. PMID 11123305  1
2000 Grunstein MM, Hakonarson H, Maskeri N, Kim C, Chuang S. Intrinsic ICAM-1/LFA-1 activation mediates altered responsiveness of atopic asthmatic airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L1154-63. PMID 10835320  1
2000 Grunstein MM, Hakonarson H, Maskeri N, Chuang S. Autocrine cytokine signaling mediates effects of rhinovirus on airway responsiveness. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L1146-53. PMID 10835319  1
1999 Hakonarson H, Maskeri N, Carter C, Chuang S, Grunstein MM. Autocrine interaction between IL-5 and IL-1beta mediates altered responsiveness of atopic asthmatic sensitized airway smooth muscle. The Journal of Clinical Investigation. 104: 657-67. PMID 10487780 DOI: 10.1172/JCI7137  1
1999 Hakonarson H, Carter C, Kim C, Grunstein MM. Altered expression and action of the low-affinity IgE receptor FcepsilonRII (CD23) in asthmatic airway smooth muscle. The Journal of Allergy and Clinical Immunology. 104: 575-84. PMID 10482830 DOI: 10.1016/S0091-6749(99)70326-X  1
1999 Hakonarson H, Carter C, Maskeri N, Hodinka R, Grunstein MM. Rhinovirus-mediated changes in airway smooth muscle responsiveness: induced autocrine role of interleukin-1beta. The American Journal of Physiology. 277: L13-21. PMID 10409226  1
1999 Hakonarson H, Maskeri N, Carter C, Grunstein MM. Regulation of TH1- and TH2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle. The Journal of Clinical Investigation. 103: 1077-87. PMID 10194481 DOI: 10.1172/JCI5809  1
1999 Rajah R, Nachajon RV, Collins MH, Hakonarson H, Grunstein MM, Cohen P. Elevated levels of the IGF-binding protein protease MMP-1 in asthmatic airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 20: 199-208. PMID 9922210 DOI: 10.1165/ajrcmb.20.2.3148  1
1998 Hakonarson H, Grunstein MM. Regulation of second messengers associated with airway smooth muscle contraction and relaxation. American Journal of Respiratory and Critical Care Medicine. 158: S115-22. PMID 9817734 DOI: 10.1164/ajrccm.158.supplement_2.13tac700  1
1998 Hakonarson H, Maskeri N, Carter C, Hodinka RL, Campbell D, Grunstein MM. Mechanism of rhinovirus-induced changes in airway smooth muscle responsiveness. The Journal of Clinical Investigation. 102: 1732-41. PMID 9802887 DOI: 10.1172/JCI4141  1
1998 Hakonarson H, Grunstein MM. Autologously up-regulated Fc receptor expression and action in airway smooth muscle mediates its altered responsiveness in the atopic asthmatic sensitized state. Proceedings of the National Academy of Sciences of the United States of America. 95: 5257-62. PMID 9560263 DOI: 10.1073/pnas.95.9.5257  1
1997 Hakonarson H, Herrick DJ, Serrano PG, Grunstein MM. Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitized airway smooth muscle. The Journal of Clinical Investigation. 99: 117-24. PMID 9011565 DOI: 10.1172/JCI119122  1
1996 Hakonarson H, Herrick DJ, Serrano PG, Grunstein MM. Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle. The Journal of Clinical Investigation. 97: 2593-600. PMID 8647953 DOI: 10.1172/JCI118708  1
1995 Hakonarson H, Herrick DJ, Grunstein MM. Mechanism of impaired beta-adrenoceptor responsiveness in atopic sensitized airway smooth muscle. The American Journal of Physiology. 269: L645-52. PMID 7491984  1
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