Trevor W. Siggers, Ph.D.
Institution:
Columbia University, New York, NYArea:
computational biophysics and bioinformaticsGoogle:
"Trevor Siggers"Mean distance: 8.77 | S | N | B | C | P |
Parents
Sign in to add mentor| Barry H. Honig | grad student | 2006 | Columbia | |
| (Aligning and modeling protein -DNA interfaces: Towards an understanding of protein-DNA binding specificity.) | ||||
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Publications
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| Carrasco Pro S, Hook H, Bray D, et al. (2023) Widespread perturbation of ETS factor binding sites in cancer. Nature Communications. 14: 913 |
| Bray D, Hook H, Zhao R, et al. (2022) CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants. Cell Genomics. 2 |
| Hook H, Zhao RW, Bray D, et al. (2022) High-Throughput Analysis of the Cell and DNA Site-Specific Binding of Native NF-κB Dimers Using Nuclear Extract Protein-Binding Microarrays (NextPBMs). Methods in Molecular Biology (Clifton, N.J.). 2366: 43-66 |
| Williams LM, Sridhar S, Samaroo J, et al. (2021) Comparison of NF-κB from the protists Capsaspora owczarzaki and Acanthoeca spectabilis reveals extensive evolutionary diversification of this transcription factor. Communications Biology. 4: 1404 |
| Williams LM, Inge MM, Mansfield KM, et al. (2019) Transcription factor NF-κB in a basal metazoan, the sponge, has conserved and unique sequences, activities, and regulation. Developmental and Comparative Immunology. 103559 |
| Bruno L, Ramlall V, Studer RA, et al. (2019) Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system. Nature Immunology |
| Penvose A, Keenan JL, Bray D, et al. (2019) Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity. Nature Communications. 10: 2514 |
| Mohaghegh N, Bray D, Keenan J, et al. (2019) NextPBM: a platform to study cell-specific transcription factor binding and cooperativity. Nucleic Acids Research. 47: e31 |
| Andrilenas KK, Ramlall V, Kurland J, et al. (2018) DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: implications for dimer-specific gene regulation. Nucleic Acids Research |
| Mansfield KM, Carter NM, Nguyen L, et al. (2017) Transcription factor NF-κB is modulated by symbiotic status in a sea anemone model of cnidarian bleaching. Scientific Reports. 7: 16025 |