Nadine S. Jahchan, Ph.D.

Affiliations: 
2010 Molecular & Cell Biology University of California, Berkeley, Berkeley, CA 
Area:
Signal transduction pathways mediated by receptors and the mechanisms controlling the activity of the receptor kinases
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"Nadine Jahchan"

Parents

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Kunxin Luo grad student 2010 UC Berkeley
 (Role of SnoN in Normal Epithelial Function and Tumorigenesis.)
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Publications

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Jahchan NS, Lim JS, Bola B, et al. (2016) Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer. Cell Reports
Weiskopf K, Jahchan NS, Schnorr PJ, et al. (2016) CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. The Journal of Clinical Investigation
Krampitz GW, George BM, Willingham SB, et al. (2016) Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proceedings of the National Academy of Sciences of the United States of America
Jahchan NS, Ouyang G, Luo K. (2013) Expression profiles of SnoN in normal and cancerous human tissues support its tumor suppressor role in human cancer. Plos One. 8: e55794
Jahchan NS, Wang D, Bissell MJ, et al. (2012) SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling. Development (Cambridge, England). 139: 3147-56
Jahchan NS, Luo K. (2010) SnoN in mammalian development, function and diseases. Current Opinion in Pharmacology. 10: 670-5
Jahchan NS, You YH, Muller WJ, et al. (2010) Transforming growth factor-beta regulator SnoN modulates mammary gland branching morphogenesis, postlactational involution, and mammary tumorigenesis. Cancer Research. 70: 4204-13
He N, Jahchan NS, Hong E, et al. (2008) A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis. Molecular Cell. 29: 588-99
Zegzouti H, Anthony RG, Jahchan N, et al. (2006) Phosphorylation and activation of PINOID by the phospholipid signaling kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1) in Arabidopsis Proceedings of the National Academy of Sciences of the United States of America. 103: 6404-6409
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