Philip B. Wedegaertner

Affiliations: 
Biochemistry and Molecular Biology Thomas Jefferson University, Philadelphia, PA, United States 
Area:
Biochemistry, Cell Biology
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"Philip Wedegaertner"
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Publications

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Rajanala K, Wedegaertner PB. (2023) Gβγ signaling regulates microtubule-dependent control of Golgi integrity. Cellular Signalling. 106: 110630
Randolph CE, Dwyer MB, Aumiller JL, et al. (2022) Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890. The Journal of Biological Chemistry. 102538
Rajanala K, Klayman LM, Wedegaertner PB. (2021) Gβγ regulates mitotic Golgi fragmentation and G2/M cell cycle progression. Molecular Biology of the Cell. mbcE21040175
Lapadula D, Farias E, Randolph CE, et al. (2018) Effects of Oncogenic Gαq and Gα11 Inhibition by FR900359 in Uveal Melanoma. Molecular Cancer Research : McR
Xiao P, Huang X, Huang L, et al. (2017) G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. Experimental Cell Research
Irannejad R, Pessino V, Mika D, et al. (2017) Functional selectivity of GPCR-directed drug action through location bias. Nature Chemical Biology
Chua V, Lapadula D, Randolph C, et al. (2017) Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma. Molecular Cancer Research : McR
Klayman LM, Wedegaertner PB. (2016) Inducible Inhibition of Gβγ Reveals Localization-Dependent Functions at the Plasma Membrane and Golgi. The Journal of Biological Chemistry
Helms MC, Grabocka E, Martz MK, et al. (2015) Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1. Cellular Signalling. 28: 43-52
Hewavitharana T, Wedegaertner PB. (2015) PAQR3 regulates Golgi vesicle fission and transport via the Gβγ-PKD signaling pathway. Cellular Signalling. 27: 2444-51
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