W Todd Lowther

Biochemistry and Molecular Biology Wake Forest University, Winston-Salem, NC, United States 
"W Lowther"
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Loberg MA, Hurtig JE, Graff AH, et al. (2019) Aromatic Residues at the Dimer-Dimer Interface in the Peroxiredoxin Tsa1 Facilitate Decamer Formation and Biological Function. Chemical Research in Toxicology
Forshaw TE, Holmila R, Nelson KJ, et al. (2019) Peroxiredoxins in Cancer and Response to Radiation Therapies. Antioxidants (Basel, Switzerland). 8
Chen X, Wu H, Park CM, et al. (2017) Discovery of Heteroaromatic Sulfones As A New Class of Biologically Compatible Thiol-Selective Reagents. Acs Chemical Biology
Hill TK, Davis AL, Wheeler FB, et al. (2016) Development of a Self-Assembled Nanoparticle Formulation of Orlistat, Nano-ORL, with Increased Cytotoxicity against Human Tumor Cell Lines. Molecular Pharmaceutics
Ritchie MK, Johnson LC, Clodfelter JE, et al. (2015) Crystal Structure and Substrate Specificity of Human Thioesterase 2: Insights into the Molecular Basis for the Modulation of Fatty Acid Synthase. The Journal of Biological Chemistry
Poynton RA, Peskin AV, Haynes AC, et al. (2015) Kinetic Analysis of Structural Influences on the Susceptibility of Peroxiredoxins 2 and 3 to Hyperoxidation. The Biochemical Journal
Cunniff B, Newick K, Nelson KJ, et al. (2015) Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma. Plos One. 10: e0127310
Summitt CB, Johnson LC, Jönsson TJ, et al. (2015) Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria. The Biochemical Journal. 466: 273-81
Haynes AC, Qian J, Reisz JA, et al. (2013) Molecular basis for the resistance of human mitochondrial 2-Cys peroxiredoxin 3 to hyperoxidation. The Journal of Biological Chemistry. 288: 29714-23
Chen H, Gu Z, Zhang H, et al. (2013) Expression and purification of integral membrane fatty acid desaturases. Plos One. 8: e58139
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