Thomas Simmen

Affiliations: 
Cell Biology University of Alberta, Edmonton, Alberta, Canada 
Area:
Endoplasmic Reticulum, mitochondria, sorting, calcium
Website:
https://www.ualberta.ca/cellbiology/people/faculty/thomas-simmen
Google:
"Thomas Simmen"
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Publications

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Bassiouni W, Mahmud Z, Simmen T, et al. (2024) MMP-2 inhibition attenuates ER stress-mediated cell death during myocardial ischemia-reperfusion injury by preserving IRE1α. Journal of Molecular and Cellular Cardiology. 198: 74-88
Makio T, Chen J, Simmen T. (2024) ER stress as a sentinel mechanism for ER Ca homeostasis. Cell Calcium. 124: 102961
Makio T, Simmen T. (2024) The Discovery of Mitochondria-Endoplasmic Reticulum Contact Sites (MERCs) as Mitochondria-Associated Membranes (MAMs). Contact (Thousand Oaks (Ventura County, Calif.)). 7: 25152564241261228
Germani S, Van Ho AT, Cherubini A, et al. (2024) SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA. Cell Reports. Medicine. 101439
Bassot A, Chen J, Takahashi-Yamashiro K, et al. (2022) The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria. Cell Reports. 111899
Bassot A, Chen J, Simmen T. (2021) Post-Translational Modification of Cysteines: A Key Determinant of Endoplasmic Reticulum-Mitochondria Contacts (MERCs). Contact (Thousand Oaks (Ventura County, Calif.)). 4: 25152564211001213
Herrera-Cruz MS, Yap MC, Tahbaz N, et al. (2021) Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins. Biology Direct. 16: 22
Chen J, Bassot A, Giuliani F, et al. (2021) Amyotrophic Lateral Sclerosis (ALS): Stressed by Dysfunctional Mitochondria-Endoplasmic Reticulum Contacts (MERCs). Cells. 10
Yousuf MS, Maguire AD, Simmen T, et al. (2020) Endoplasmic reticulum-mitochondria interplay in chronic pain: The calcium connection. Molecular Pain. 16: 1744806920946889
Yousuf MS, Samtleben S, Lamothe SM, et al. (2020) Endoplasmic reticulum stress in the dorsal root ganglia regulates large-conductance potassium channels and contributes to pain in a model of multiple sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
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