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Walter E. Mushynski, Ph.D.

Biochemistry McGill University, Montreal, QC, Canada 
Biochemistry, Neurofilaments
"Walter Mushynski"

Professor Emeritus
Department of Biochemistry

Role of phosphorylation in normal and pathological aspects of neurofilament metabolism

1970 - PhD, McGill University

Cross-listing: Neurotree - Chemistry Tree


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Jean Pierre Julien grad student McGill (Neurotree)
Michael Sacher grad student McGill
Benoit I. Giasson grad student 1991-1997 McGill (Neurotree)
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Gentil BJ, Mushynski WE, Durham HD. (2013) Heterogeneity in the properties of NEFL mutants causing Charcot-Marie-Tooth disease results in differential effects on neurofilament assembly and susceptibility to intervention by the chaperone-inducer, celastrol. The International Journal of Biochemistry & Cell Biology. 45: 1499-508
Hossain S, Fragoso G, Mushynski WE, et al. (2010) Regulation of peripheral myelination by Src-like kinases. Experimental Neurology. 226: 47-57
Haines JD, Fang J, Mushynski WE, et al. (2010) Mitogen-activated protein kinase activated protein kinase 2 (MK2) participates in p38 MAPK regulated control of oligodendrocyte differentiation. Glia. 58: 1384-93
Larocque D, Fragoso G, Huang J, et al. (2009) The QKI-6 and QKI-7 RNA binding proteins block proliferation and promote Schwann cell myelination. Plos One. 4: e5867
Haines JD, Fragoso G, Hossain S, et al. (2008) p38 Mitogen-activated protein kinase regulates myelination. Journal of Molecular Neuroscience : Mn. 35: 23-33
Fragoso G, Haines JD, Roberston J, et al. (2007) p38 mitogen-activated protein kinase is required for central nervous system myelination. Glia. 55: 1531-41
Jacomy H, Fragoso G, Almazan G, et al. (2006) Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice. Virology. 349: 335-46
Fragoso G, Martínez-Bermúdez AK, Liu HN, et al. (2004) Developmental differences in HO-induced oligodendrocyte cell death: role of glutathione, mitogen-activated protein kinases and caspase 3. Journal of Neurochemistry. 90: 392-404
Fragoso G, Robertson J, Athlan E, et al. (2003) Inhibition of p38 mitogen-activated protein kinase interferes with cell shape changes and gene expression associated with Schwann cell myelination. Experimental Neurology. 183: 34-46
Robertson J, Doroudchi MM, Nguyen MD, et al. (2003) A neurotoxic peripherin splice variant in a mouse model of ALS. The Journal of Cell Biology. 160: 939-49
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