Justin A. Spanier, Ph.D.

Affiliations: 
2011 University of Wisconsin, Madison, Madison, WI 
Area:
Immunology
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"Justin Spanier"

Parents

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Colleen E. Hayes grad student 2011 UW Madison
 (Mechanisms of vitamin D-mediated suppression of experimental autoimmune encephalomyelitis.)
Brian T. Fife post-doc 2012-2017 UMN (Microtree)
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Publications

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Mitchell JS, Spanier JA, Dwyer AJ, et al. (2024) CD4 T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes. Immunity
Wardell CM, Fung VCW, Chen E, et al. (2024) CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation. Biorxiv : the Preprint Server For Biology
Spanier JA, Fung V, Wardell CM, et al. (2023) Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes in mice. The Journal of Clinical Investigation
Spanier JA, Fung V, Wardell CM, et al. (2023) Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes. Biorxiv : the Preprint Server For Biology
Choi JW, Withers SS, Chang H, et al. (2020) Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function. Plos One. 15: e0235518
Spanier JA, Nashold FE, Nelson CD, et al. (2019) Vitamin D-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D synthesis and correlates with increased CD4 T cell CTLA-4 expression. Journal of Neuroimmunology. 338: 577105
Martinov T, Swanson LA, Breed ER, et al. (2019) Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes. Journal of Immunology (Baltimore, Md. : 1950)
Spanier JA, Tse HM, Horwitz MS, et al. (2019) Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes. Frontiers in Endocrinology. 10: 315
Owen DL, Mahmud SA, Sjaastad LE, et al. (2019) Thymic regulatory T cells arise via two distinct developmental programs. Nature Immunology
Moore JR, Hubler SL, Nelson CD, et al. (2018) 1,25-Dihydroxyvitamin D increases the methionine cycle, CD4 T cell DNA methylation and HeliosFoxp3 T regulatory cells to reverse autoimmune neurodegenerative disease. Journal of Neuroimmunology. 324: 100-114
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