Andrew D. Slack, Ph.D.

2001 McGill University, Montreal, QC, Canada 
Pharmacology, Oncology, Molecular Biology
"Andrew Slack"


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Moshe Szyf grad student 2001 McGill
 (Roles of the DNA methylation machinery in cellular transformation and tumorigenesis.)
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Hastings PJ, Hersh MN, Thornton PC, et al. (2010) Competition of Escherichia coli DNA polymerases I, II and III with DNA Pol IV in stressed cells. Plos One. 5: e10862
Slack AD, Chen Z, Ludwig AD, et al. (2007) MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cells. Cancer Research. 67: 2448-55
Slack A, Thornton PC, Magner DB, et al. (2006) On the mechanism of gene amplification induced under stress in Escherichia coli Plos Genetics. 2
Guo Y, Pakneshan P, Gladu J, et al. (2002) Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion. The Journal of Biological Chemistry. 277: 41571-9
Slack A, Bovenzi V, Bigey P, et al. (2002) Antisense MBD2 gene therapy inhibits tumorigenesis Journal of Gene Medicine. 4: 381-389
Slack A, Pinard M, Araujo FD, et al. (2001) A novel regulatory element in the dnmt1 gene that responds to co-activation by Rb and c-Jun Gene. 268: 87-96
Araujo FD, Croteau S, Slack AD, et al. (2001) The DNMT1 target recognition domain resides in the N terminus. The Journal of Biological Chemistry. 276: 6930-6
Szyf M, Slack AD. (2000) Mechanisms of epigenetic silencing of the c21 gene in Y1 adrenocortical tumor cells. Endocrine Research. 26: 921-30
Szyf M, Knox DJ, Milutinovic S, et al. (2000) How does DNA methyltransferase cause oncogenic transformation? Annals of the New York Academy of Sciences. 910: 156-74; discussion 1
Knox JD, Araujo FD, Bigey P, et al. (2000) Inhibition of DNA methyltransferase inhibits DNA replication. The Journal of Biological Chemistry. 275: 17986-90
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