Herbert Y. Gaisano

Affiliations: 
Medical Science University of Toronto, Toronto, ON, Canada 
Area:
Physiology Biology, Cell Biology
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"Herbert Gaisano"
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Publications

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Xie L, Kang F, Qin T, et al. (2025) Septin5 deletion enhances β-cell exocytosis by releasing microtubule-tethered insulin granules onto plasma membrane. Nature Communications. 16: 2725
Piro A, Luo Y, Zhang Z, et al. (2024) Beta cell specific ZnT8 gene deficiency and resulting loss in zinc content significantly improve insulin secretion. Molecular and Cellular Endocrinology. 112376
Kang F, Xie L, Qin T, et al. (2022) Plasma membrane flipping of Syntaxin-2 regulates its inhibitory action on insulin granule exocytosis. Nature Communications. 13: 6512
Takahashi T, Miao Y, Kang F, et al. (2020) Susceptibility Factors And Cellular Mechanisms Underlying Alcoholic Pancreatitis. Alcoholism, Clinical and Experimental Research
Liang T, Qin T, Kang F, et al. (2020) SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes. Jci Insight. 5
Wen J, Cai X, Zhang J, et al. (2020) Relation of adipose tissue insulin resistance to prediabetes. Endocrine
Thurmond DC, Gaisano HY. (2019) Recent insights into beta-cell exocytosis in type 2 diabetes. Journal of Molecular Biology
Cornick S, Kumar M, Moreau F, et al. (2019) VAMP8-mediated MUC2 mucin exocytosis from colonic goblet cells maintains innate intestinal homeostasis. Nature Communications. 10: 4306
Luck H, Khan S, Kim JH, et al. (2019) Gut-associated IgA immune cells regulate obesity-related insulin resistance. Nature Communications. 10: 3650
Piplani H, Marek-Iannucci S, Sin J, et al. (2019) Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis. Biochimica Et Biophysica Acta. Molecular Basis of Disease
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